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Li Jing Xu
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22
Martin, James
13
Gordon, Robert
11
Brideau, Christine
10
Charleson, Stella
10
Riendeau, Denis
9
Prasit, Peppi
9
Chan, Chi Chung
8
Guay, Jocelyne
8
Powell, William
8
Renzi, Paolo
8
Wang, Zhaoyin
7
Ethier, Diane
7
Cromlish, Wanda
7
visco, Denise
6
Leblanc, Yves
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All Publications
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2009: Mamane Yaël; Chung Chan Chi; Lavallee Genevieve; Morin Nicolas; Xu Li-Jing; Huang JingQi; Gordon Robert; Thomas Winston; Lamb John; Schadt Eric E; Kennedy Brian P; Mancini Joseph A
The C3a anaphylatoxin receptor is a key mediator of insulin resistance and functions by modulating adipose tissue macrophage infiltration and activation.
Diabetes 2009;58(9):2006-17.
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2008: Pulichino Anne-Marie; Wang I-Ming; Caron Alexandre; Mortimer James; Auger Anick; Boie Yves; Elias Jack A; Kartono Aileen; Xu Lijing; Menetski Joseph; Sayegh Camil E
Identification of transforming growth factor beta1-driven genetic programs of acute lung fibrosis.
American journal of respiratory cell and molecular biology 2008;39(3):324-36.
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2004: Dufresne Claude; Roy Patrick; Wang Zhaoyin; Asante-Appiah Ernest; Cromlish Wanda; Boie Yves; Forghani Farnaz; Desmarais Sylvie; Wang Qingping; Skorey Kathryn; Waddleton Deena; Ramachandran Chidambaram; Kennedy Brian P; Xu Lijing; Gordon Robert; Chan Chi Chung; Leblanc Yves
The development of potent non-peptidic PTP-1B inhibitors.
Bioorganic & medicinal chemistry letters 2004;14(4):1039-42.
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2003: Black W Cameron; Brideau Christine; Chan Chi Chung; Charleson Stella; Cromlish Wanda; Gordon Robert; Grimm Erich L; Hughes Gregory; Leger Serge; Li Chun Sing; Riendeau Denis; Thérien Michel; Wang Zhaoyin; Xu Li Jing; Prasit Petpiboon
3,4-Diaryl-5-hydroxyfuranones: highly selective inhibitors of cyclooxygenase-2 with aqueous solubility.
Bioorganic & medicinal chemistry letters 2003;13(6):1195-8.
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2003: Nag Sammy S; Xu Li Jing; Hamid Qutayba; Renzi Paolo M
The effects of IL-5 on airway physiology and inflammation in rats.
The Journal of allergy and clinical immunology 2003;111(3):558-66.
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2002: Leblanc Yves; Roy Patrick; Wang Zhaoyin; Li Chun Sing; Chauret Nathalie; Nicoll-Griffith Deborah A; Silva José M; Aubin Yves; Yergey James A; Chan Chi Chung; Riendeau Denis; Brideau Christine; Gordon Robert; Xu Lijing; Webb Janine; Visco Denise M; Prasit Petpiboon
Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile.
Bioorganic & medicinal chemistry letters 2002;12(22):3317-20.
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2001: Bateman K P; Castonguay G; Xu L; Rowland S; Nicoll-Griffith D A; Kelly N; Chan C C
Reduction of animal usage by serial bleeding of mice for pharmacokinetic studies: application of robotic sample preparation and fast liquid chromatography-mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications 2001;754(1):245-51.
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2001: Riendeau D; Percival M D; Brideau C; Charleson S; Dubé D; Ethier D; Falgueyret J P; Friesen R W; Gordon R; Greig G; Guay J; Mancini J; Ouellet M; Wong E; Xu L; Boyce S; Visco D; Girard Y; Prasit P; Zamboni R; Rodger I W; Gresser M; Ford-Hutchinson A W; Young R N; Chan C C
Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.
The Journal of pharmacology and experimental therapeutics 2001;296(2):558-66.
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2000: Xu L; Olivenstein R; Martin J G; Powell W S
Inhaled budesonide inhibits OVA-induced airway narrowing, inflammation, and cys-LT synthesis in BN rats.
Journal of applied physiology (Bethesda, Md. : 1985) 2000;89(5):1852-8.
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1999: Lau C K; Brideau C; Chan C C; Charleson S; Cromlish W A; Ethier D; Gauthier J Y; Gordon R; Guay J; Kargman S; Li C S; Prasit P; Riendeau D; Thérien M; Visco D M; Xu L
Synthesis and biological evaluation of 3-heteroaryloxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors.
Bioorganic & medicinal chemistry letters 1999;9(22):3187-92.
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1999: Li C S; Black W C; Brideau C; Chan C C; Charleson S; Cromlish W A; Claveau D; Gauthier J Y; Gordon R; Greig G; Grimm E; Guay J; Lau C K; Riendeau D; Thérien M; Visco D M; Wong E; Xu L; Prasit P
A new structural variation on the methanesulfonylphenyl class of selective cyclooxygenase-2 inhibitors.
Bioorganic & medicinal chemistry letters 1999;9(22):3181-6.
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1999: Leblanc Y; Roy P; Boyce S; Brideau C; Chan C C; Charleson S; Gordon R; Grimm E; Guay J; Léger S; Li C S; Riendeau D; Visco D; Wang Z; Webb J; Xu L J; Prasit P
SAR in the alkoxy lactone series: the discovery of DFP, a potent and orally active COX-2 inhibitor.
Bioorganic & medicinal chemistry letters 1999;9(15):2207-12.
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1999: Chan C C; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Ford-Hutchinson A W; Forrest M J; Gauthier J Y; Gordon R; Gresser M; Guay J; Kargman S; Kennedy B; Leblanc Y; Leger S; Mancini J; O'Neill G P; Ouellet M; Patrick D; Percival M D; Perrier H; Prasit P; Rodger I
Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.
The Journal of pharmacology and experimental therapeutics 1999;290(2):551-60.
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1999: Prasit P; Wang Z; Brideau C; Chan C C; Charleson S; Cromlish W; Ethier D; Evans J F; Ford-Hutchinson A W; Gauthier J Y; Gordon R; Guay J; Gresser M; Kargman S; Kennedy B; Leblanc Y; Léger S; Mancini J; O'Neill G P; Ouellet M; Percival M D; Perrier H; Riendeau D; Rodger I; Zamboni R
The discovery of rofecoxib, [MK 966, Vioxx, 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2-inhibitor.
Bioorganic & medicinal chemistry letters 1999;9(13):1773-8.
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1999: Renzi P M; Xu L; Yang X X; Powell W S; Martin J G
IL-2 enhances allergic airway responses in rats by increased inflammation but not through increased synthesis of cysteinyl leukotrienes.
The Journal of allergy and clinical immunology 1999;104(1):145-52.
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1999: Du T; Martin J G; Xu L J; Powell W S; Renzi P M
IL-3 does not affect the allergic airway responses and leukotriene production after allergen challenge in rats.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;13(5):970-5.
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1999: Black W C; Brideau C; Chan C C; Charleson S; Chauret N; Claveau D; Ethier D; Gordon R; Greig G; Guay J; Hughes G; Jolicoeur P; Leblanc Y; Nicoll-Griffith D; Ouimet N; Riendeau D; Visco D; Wang Z; Xu L; Prasit P
2,3-Diarylcyclopentenones as orally active, highly selective cyclooxygenase-2 inhibitors.
Journal of medicinal chemistry 1999;42(7):1274-81.
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1999: Yang X X; Powell W S; Xu L J; Martin J G
Strain dependence of the airway response to dry-gas hyperpnea challenge in the rat.
Journal of applied physiology (Bethesda, Md. : 1985) 1999;86(1):152-8.
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1999: Yang X X; Ho G; Xu L J; Powell W S; Martin J G
The beta(2)-agonist salbutamol inhibits bronchoconstriction and leukotriene D(4) synthesis after dry gas hyperpnea in the guinea-pig.
Pulmonary pharmacology & therapeutics 1999;12(5):325-9.
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1998: Friesen R W; Brideau C; Chan C C; Charleson S; Deschênes D; Dubé D; Ethier D; Fortin R; Gauthier J Y; Girard Y; Gordon R; Greig G M; Riendeau D; Savoie C; Wang Z; Wong E; Visco D; Xu L J; Young R N
2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: selective and orally active cyclooxygenase-2 inhibitors.
Bioorganic & medicinal chemistry letters 1998;8(19):2777-82.
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1997: Olivenstein R; Du T; Xu L J; Martin J G
Microvascular leakage in the airway wall and lumen during allergen induced early and late responses in rats.
Pulmonary pharmacology & therapeutics 1997;10(4):223-30.
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1997: Riendeau D; Percival M D; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Falgueyret J P; Ford-Hutchinson A W; Gordon R; Greig G; Gresser M; Guay J; Kargman S; Léger S; Mancini J A; O'Neill G; Ouellet M; Rodger I W; Thérien M; Wang Z; Webb J K; Wong E; Chan C C
Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
British journal of pharmacology 1997;121(1):105-17.
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1996: Laberge S; Wu L; Olivenstein R; Xu L J; Renzi P M; Martin J G
Depletion of CD8+ T cells enhances pulmonary inflammation but not airway responsiveness after antigen challenge in rats.
The Journal of allergy and clinical immunology 1996;98(3):617-27.
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1996: Jia Y; Xu L; Turner D J; Martin J G
Endogenous nitric oxide contributes to strain-related differences in airway responsiveness in rats.
Journal of applied physiology (Bethesda, Md. : 1985) 1996;80(2):404-10.
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1995: Yu W; Xu L; Martin J G; Powell W S
Cellular infiltration and eicosanoid synthesis in brown Norway rat lungs after allergen challenge.
American journal of respiratory cell and molecular biology 1995;13(4):477-86.
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1995: Watanabe A; Mishima H; Renzi P M; Xu L J; Hamid Q; Martin J G
Transfer of allergic airway responses with antigen-primed CD4+ but not CD8+ T cells in brown Norway rats.
The Journal of clinical investigation 1995;96(3):1303-10.
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1995: Jia Y; Xu L; Heisler S; Martin J G
Airways of a hyperresponsive rat strain show decreased relaxant responses to sodium nitroprusside.
The American journal of physiology 1995;269(1 Pt 1):L85-91.
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1995: Watanabe A; Rossi P; Renzi P M; Xu L J; Guttmann R D; Martin J G
Adoptive transfer of allergic airway responses with sensitized lymphocytes in BN rats.
American journal of respiratory and critical care medicine 1995;152(1):64-70.
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1995: Powell W S; Xu L J; Martin J G
Effects of dexamethasone on leukotriene synthesis and airway responses to antigen and leukotriene D4 in rats.
American journal of respiratory and critical care medicine 1995;151(4):1143-50.
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1995: Waserman S; Xu L J; Olivenstein R; Renzi P M; Martin J G
Association between late allergic bronchoconstriction in the rat and allergen-stimulated lymphocyte proliferation in vitro.
American journal of respiratory and critical care medicine 1995;151(2 Pt 1):470-4.
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1993: Rossi P; Xu L; Wang N S; Martin J G
Allergen-induced airway responses in rats pretreated with Sephadex.
Agents and actions 1993;40(3-4):141-9.
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1993: Wang C G; Du T; Xu L J; Martin J G
Role of leukotriene D4 in allergen-induced increases in airway smooth muscle in the rat.
The American review of respiratory disease 1993;148(2):413-7.
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1993: Dandurand R J; Xu L J; Martin J G; Eidelman D H
Airway-parenchymal interdependence and bronchial responsiveness in two highly inbred rat strains.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(2):538-44.
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1993: Martin J G; Xu L J; Toh M Y; Olivenstein R; Powell W S
Leukotrienes in bile during the early and the late airway responses after allergen challenge of sensitized rats.
The American review of respiratory disease 1993;147(1):104-10.
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1993: Xu L J; Dandurand R J; Lei M; Eidelman D H
Airway hyperresponsiveness in cigarette smoke-exposed rats.
Lung 1993;171(2):95-107.
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1992: Xu L J; Sapienza S; Du T; Waserman S; Martin J G
Comparison of upper and lower airway responses of two sensitized rat strains to inhaled antigen.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;73(4):1608-13.
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1992: Du T; Xu L J; Lei M; Wang N S; Eidelman D H; Ghezzo H; Martin J G
Morphometric changes during the early airway response to allergen challenge in the rat.
The American review of respiratory disease 1992;146(4):1037-41.
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1992: Waserman S; Olivenstein R; Renzi P; Xu L J; Martin J G
The relationship between late asthmatic responses and antigen-specific immunoglobulin.
The Journal of allergy and clinical immunology 1992;90(4 Pt 1):661-9.
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1990: Mortola J P; Xu L J; Lauzon A M
Body growth, lung and heart weight, and DNA content in newborn rats exposed to different levels of chronic hypoxia.
Canadian journal of physiology and pharmacology 1990;68(12):1590-4.
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1990: Xu L J; Eidelman D H; Bates J H; Martin J G
Late response of the upper airway of the rat to inhaled antigen.
Journal of applied physiology (Bethesda, Md. : 1985) 1990;69(4):1360-5.
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1989: Xu L J; Mortola J P
Effects of hypoxia or hyperoxia on the lung of the chick embryo.
Canadian journal of physiology and pharmacology 1989;67(5):515-9.
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1988: Xu L; Mortola J P
Development of the chick embryo: effects of egg mass.
Respiration physiology 1988;74(2):177-85.
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