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Ming-Hua Xu

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TOP 3
Yue-Na Yu; Ming-Hua Xu
Enantioselective synthesis of chiral 3-aryl-1-indanones through rhodium-catalyzed asymmetric intramolecular 1,4-addition.
Diao Chen; Ming-Hua Xu
Zn-mediated asymmetric allylation of N-tert-butanesulfinyl ketimines: an efficient and practical access to chiral quaternary 3-aminooxindoles.
Jiahui Wu; Ming-Hua Xu; Kaixian Chen; Hualiang Jiang; Yi Li; Dongxiang Liu
Identification of benzofuran-3-yl(phenyl)methanones as novel SIRT1 inhibitors: binding mode, inhibitory mechanism and biological action.

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All Publications

2013: Yue-Na Yu; Ming-Hua Xu
Enantioselective synthesis of chiral 3-aryl-1-indanones through rhodium-catalyzed asymmetric intramolecular 1,4-addition.
The Journal of organic chemistry 2013;78(6):2736-41.
2013: Diao Chen; Ming-Hua Xu
Zn-mediated asymmetric allylation of N-tert-butanesulfinyl ketimines: an efficient and practical access to chiral quaternary 3-aminooxindoles.
Chemical communications (Cambridge, England) 2013;49(13):1327-9.
2013: Jiahui Wu; Ming-Hua Xu; Kaixian Chen; Hualiang Jiang; Yi Li; Dongxiang Liu
Identification of benzofuran-3-yl(phenyl)methanones as novel SIRT1 inhibitors: binding mode, inhibitory mechanism and biological action.
European journal of medicinal chemistry 2013;60():441-50.
2013: Hui Wang; Tao Jiang; Ming-Hua Xu
Simple branched sulfur-olefins as chiral ligands for Rh-catalyzed asymmetric arylation of cyclic ketimines: highly enantioselective construction of tetrasubstituted carbon stereocenters.
Journal of the American Chemical Society 2013;135(3):971-4.
2013: Ting-Shun Zhu; Jian-Ping Chen; Ming-Hua Xu
Rhodium-catalyzed enantioselective addition to unsymmetrical α-diketones: tandem one-pot synthesis of optically active 3-tetrasubstituted isochroman derivatives.
Chemistry (Weinheim an der Bergstrasse, Germany) 2013;19(3):865-9.
2012: Hui Wang; Ting-Shun Zhu; Ming-Hua Xu
Rhodium-catalyzed enantioselective 1,2-addition of arylboronic acids to heteroaryl α-ketoesters for synthesis of heteroaromatic α-hydroxy esters.
Organic & biomolecular chemistry 2012;10(46):9158-64.
2012: Ting-Shun Zhu; Ming-Hua Xu
Efficient synthesis of optically active α-quaternary amino acids by highly diastereoselective [2,3]-rearrangement of allylic ammonium ylides.
Chemical communications (Cambridge, England) 2012;48(58):7274-6.
2012: Yi Li; Ming-Hua Xu
Lewis acid promoted highly diastereoselective Petasis Borono-Mannich reaction: efficient synthesis of optically active β,γ-unsaturated α-amino acids.
Organic letters 2012;14(8):2062-5.
2012: Shen-Shuang Jin; Hui Wang; Ting-Shun Zhu; Ming-Hua Xu
Design of N-cinnamyl sulfinamides as new sulfur-containing olefin ligands for asymmetric catalysis: achieving structural simplicity with a categorical linear framework.
Organic & biomolecular chemistry 2012;10(9):1764-8.
2011: Yi Li; Du-Ming Ji; Ming-Hua Xu
Highly diastereoselective Friedel-Crafts reaction of arenes with N-tert-butanesulfinylimino ester towards the efficient synthesis of α-arylglycines.
Organic & biomolecular chemistry 2011;9(24):8452-8.
2011: Shen-Shuang Jin; Hui Wang; Ming-Hua Xu
Design of N-sulfinyl homoallylic amines as novel sulfinamide-olefin hybrid ligands for asymmetric catalysis: application in Rh-catalyzed enantioselective 1,4-additions.
Chemical communications (Cambridge, England) 2011;47(25):7230-2.
2011: Wei-Yi Qi; Ting-Shun Zhu; Ming-Hua Xu
Design of chiral sulfoxide-olefins as a new class of sulfur-based olefin ligands for asymmetric catalysis.
Organic letters 2011;13(13):3410-3.
2010: Hong-Yu Yang; Ming-Hua Xu
Rhodium/diene-catalyzed asymmetric arylation of N-sulfonyl indolylimines: a new access to highly optically active α-aryl 3-indolyl-methanamines.
Chemical communications (Cambridge, England) 2010;46(48):9223-5.
2010: Shu-Sheng Zhang; Zhi-Qian Wang; Ming-Hua Xu; Guo-Qiang Lin
Chiral diene as the ligand for the synthesis of axially chiral compounds via palladium-catalyzed Suzuki-Miyaura coupling reaction.
Organic letters 2010;12(23):5546-9.
2010: Min Liu; An Shen; Xing-Wen Sun; Fei Deng; Ming-Hua Xu; Guo-Qiang Lin
Dramatic lithium chloride effect on the reaction stereocontrol in Zn-mediated asymmetric cinnamylation: highly practical synthesis of β-aryl homoallylic amines.
Chemical communications (Cambridge, England) 2010;46(44):8460-2.
2010: An Shen; Min Liu; Zhen-Shan Jia; Ming-Hua Xu; Guo-Qiang Lin
One-pot synthesis of chiral α-methylene-γ-lactams with excellent diastereoselectivities and enantioselectivities.
Organic letters 2010;12(22):5154-7.
2010: Zhi-Qian Wang; Chen-Guo Feng; Shu-Sheng Zhang; Ming-Hua Xu; Guo-Qiang Lin
Rhodium-catalyzed asymmetric conjugate addition of organoboronic acids to nitroalkenes using chiral bicyclo[3.3.0] diene ligands.
Angewandte Chemie (International ed. in English) 2010;49(33):5780-3.
2010: Lei Chen; Yi Li; Ming-Hua Xu
One-pot synthesis of furocoumarins via sequential Pd/Cu-catalyzed alkynylation and intramolecular hydroalkoxylation.
Organic & biomolecular chemistry 2010;8(13):3073-7.
2010: Wen-Wen Chen; Qian Zhao; Ming-Hua Xu; Guo-Qiang Lin
Nickel-catalyzed asymmetric Ullmann coupling for the synthesis of axially chiral tetra-ortho-substituted biaryl dials.
Organic letters 2010;12(5):1072-5.
2009: Bo Zhang; Ming-Hua Xu; Guo-Qiang Lin
Catalytic enantioselective synthesis of chiral phthalides by efficient reductive cyclization of 2-acylarylcarboxylates under aqueous transfer hydrogenation conditions.
Organic letters 2009;11(20):4712-5.
2009: Min Liu; Xing-Wen Sun; Ming-Hua Xu; Guo-Qiang Lin
Highly efficient asymmetric synthesis of vinylic amino alcohols by Zn-promoted benzoyloxyallylation of chiral N-tert-butanesulfinyl imines: facile and rapid access to (-)-cytoxazone.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(39):10217-24.
2008: Chen-Guo Feng; Zhi-Qian Wang; Ping Tian; Ming-Hua Xu; Guo-Qiang Lin
Easily accessible C2-symmetric chiral bicyclo[3.3.0] dienes as ligands for rhodium-catalyzed asymmetric 1,4-addition.
Chemistry, an Asian journal 2008;3(8-9):1511-6.
2008: Chen Zhu; Yun Shi; Ming-Hua Xu; Guo-Qiang Lin
An efficient and versatile approach for optical resolution of C2-symmetric axially chiral biaryl dials. Synthesis of enantiopure biaryl-derived cyclic trans-1,2-diols.
Organic letters 2008;10(6):1243-6.
2008: Xing-Wen Sun; Min Liu; Ming-Hua Xu; Guo-Qiang Lin
Remarkable salt effect on In-mediated allylation of N-tert-butanesulfinyl imines in aqueous media: highly practical asymmetric synthesis of chiral homoallylic amines and isoindolinones.
Organic letters 2008;10(6):1259-62.
2007: Zhi-Qian Wang; Chen-Guo Feng; Ming-Hua Xu; Guo-Qiang Lin
Design of C2-symmetric tetrahydropentalenes as new chiral diene ligands for highly enantioselective Rh-catalyzed arylation of N-tosylarylimines with arylboronic acids.
Journal of the American Chemical Society 2007;129(17):5336-7.
2006: Xing-Wen Sun; Ming-Hua Xu; Guo-Qiang Lin
Room-temperature highly diastereoselective Zn-mediated allylation of chiral N-tert-butanesulfinyl imines: remarkable reaction condition controlled stereoselectivity reversal.
Organic letters 2006;8(21):4979-82.
2006: Ling-Lin Huang; Ming-Hua Xu; Guo-Qiang Lin
Catalytic enantioselective synthesis of chiral phthalides by SmI2-mediated reductive cyclization of 2-acylarylcarboxylates.
Journal of the American Chemical Society 2006;128(17):5624-5.
2005: Yu-Wu Zhong; Yi-Zhou Dong; Kai Fang; Kenji Izumi; Ming-Hua Xu; Guo-Qiang Lin
A highly efficient and direct approach for synthesis of enantiopure beta-amino alcohols by reductive cross-coupling of chiral N-tert-butanesulfinyl imines with aldehydes.
Journal of the American Chemical Society 2005;127(34):11956-7.
2005: Ling-Lin Huang; Ming-Hua Xu; Guo-Qiang Lin
A new entry to asymmetric synthesis of optically active alpha,gamma-substituted gamma-butyrolactones, using a carbohydrate derived amide as both a chiral auxiliary and a proton source.
The Journal of organic chemistry 2005;70(2):529-32.
2004: Yu-Wu Zhong; Kenji Izumi; Ming-Hua Xu; Guo-Qiang Lin
Highly diastereoselective and enantioselective synthesis of enantiopure C2-Symmetrical vicinal diamines by reductive homocoupling of chiral N-tert-butanesulfinyl imines.
Organic letters 2004;6(25):4747-50.
2004: Yu-Wu Zhong; Ming-Hua Xu; Guo-Qiang Lin
Samarium diiodide-induced asymmetric synthesis of optically pure unsymmetrical vicinal diamines by reductive cross-coupling of nitrones with N-tert-butanesulfinyl imines.
Organic letters 2004;6(22):3953-6.
2001: Zhi-Yong Liao; Yue-Hua Tang; Ming-Hua Xu; You-Min Feng; Shang-Quan Zhu
B9-serine residue is crucial for insulin actions in glucose metabolism.
Acta pharmacologica Sinica 2001;22(10):939-43.
2001: Ming-Hua Xu; W Wang; L J Xia; Guo-Qiang Lin
Development of a new reaction system for the synthesis of highly optically active alpha,gamma-substituted gamma-butyrolactones.
The Journal of organic chemistry 2001;66(11):3953-62.
2000: Ming-Hua Xu; W Wang; Guo-Qiang Lin
A highly efficient asymmetric synthesis of optically active alpha, gamma-substituted gamma-butyrolactones using a chiral auxiliary derived from isosorbide.
Organic letters 2000;2(15):2229-32.