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Marie-Christine Brezak

Research Profile

Chemicals & Drugs

Living Beings

Physiology

Anatomy

Procedures

Xenograft Model Antitumor Assays

Concepts & Ideas

Mitosis

Disorders

Pancreatic Neoplasms

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Co-author Network

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Publications

TOP 3
Marie-Christine Brezak; Annie Valette; Muriel Quaranta; Marie-Odile Contour-Galcera; Denis Jullien; Olivier Lavergne; Céline Frongia; Dennis Bigg; Philip G Kasprzyk; Grégoire Pierre Prevost; BERNARD DUCOMMUN
IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells.
Martine Cazales; Rose Boutros; Marie-Christine Brezak; Sophie Chaumeron; Grégoire Prevost; BERNARD DUCOMMUN
Pharmacologic inhibition of CDC25 phosphatases impairs interphase microtubule dynamics and mitotic spindle assembly.
Grégoire Prévost; Marie O Lonchampt; Susan Holbeck; Samir Attoub; Daniel W Zaharevitz; Mike Alley; John Wright; Marie-Christine Brezak; Hélène Coulomb; Ann Savola; Marion Huchet; Sophie Chaumeron; Quang-Dé Nguyen; Patricia Forgez; Erik Bruyneel; Marc Bracke; Eric Ferrandis; Pierre Roubert; Danièle Demarquay; Christian Gespach; Philip G Kasprzyk
Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric Galpha/Gbetagamma protein complex.

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All Publications

2009: Marie-Christine Brezak; Annie Valette; Muriel Quaranta; Marie-Odile Contour-Galcera; Denis Jullien; Olivier Lavergne; Céline Frongia; Dennis Bigg; Philip G Kasprzyk; Grégoire Pierre Prevost; BERNARD DUCOMMUN
IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells.
International journal of cancer. Journal international du cancer 2009;124(6):1449-56.
2007: Martine Cazales; Rose Boutros; Marie-Christine Brezak; Sophie Chaumeron; Grégoire Prevost; BERNARD DUCOMMUN
Pharmacologic inhibition of CDC25 phosphatases impairs interphase microtubule dynamics and mitotic spindle assembly.
Molecular cancer therapeutics 2007;6(1):318-25.
2006: Grégoire Prévost; Marie O Lonchampt; Susan Holbeck; Samir Attoub; Daniel W Zaharevitz; Mike Alley; John Wright; Marie-Christine Brezak; Hélène Coulomb; Ann Savola; Marion Huchet; Sophie Chaumeron; Quang-Dé Nguyen; Patricia Forgez; Erik Bruyneel; Marc Bracke; Eric Ferrandis; Pierre Roubert; Danièle Demarquay; Christian Gespach; Philip G Kasprzyk
Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric Galpha/Gbetagamma protein complex.
Cancer research 2006;66(18):9227-34.
2006: Béatrix Bugler; Muriel Quaranta; Bernadette ARESSY; Marie-Christine Brezak; Grégoire Prevost; BERNARD DUCOMMUN
Genotoxic-activated G2-M checkpoint exit is dependent on CDC25B phosphatase expression.
Molecular cancer therapeutics 2006;5(6):1446-51.
2005: Marie-Christine Brezak; Muriel Quaranta; Marie-Odile Contour-Galcera; Olivier Lavergne; Odile Mondesert; Pierrïck Auvray; Philip G Kasprzyk; Grégoire Prevost; BERNARD DUCOMMUN
Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of CDC25 phosphatases.
Molecular cancer therapeutics 2005;4(9):1378-87.
2004: Marie-Odile Contour-Galcéra; Olivier Lavergne; Marie-Christine Brezak; BERNARD DUCOMMUN; Grégoire Prévost
Synthesis of small molecule CDC25 phosphatases inhibitors.
Bioorganic & medicinal chemistry letters 2004;14(23):5809-12.
2004: Marie-Christine Brezak; Muriel Quaranta; Odile Mondésert; Marie-Odile Galcera; Olivier Lavergne; Frédéric Alby; Martine Cazales; Véronique Baldin; Christophe Thurieau; Jeremiah J Harnett; Christophe Lanco; Philip G Kasprzyk; Grégoire Prevost; BERNARD DUCOMMUN
A novel synthetic inhibitor of CDC25 phosphatases: BN82002.
Cancer research 2004;64(9):3320-5.
2004: Odile Mondesert; Matthieu Lemaire; Marie-Christine Brezak; Marie Odile Galera-Contour; Grégoire Prevost; BERNARD DUCOMMUN; Béatrix Bugler
A fission yeast strain expressing human CDC25A phosphatase: a tool for selectivity studies of pharmacological inhibitors of CDC25.
Current genetics 2004;45(5):283-8.
2003: Jean Michel Vicat; Hector Ardila-Osorio; Abdelmajid Khabir; Marie-Christine Brezak; Isabelle Viossat; Philip G Kasprzyk; Rachid Jlidi; Paule Opolon; Tadamasa Ooka; Grégoire Prevost; Dolly P Huang; Pierre Busson
Apoptosis and TRAF-1 cleavage in Epstein-Barr virus-positive nasopharyngeal carcinoma cells treated with doxorubicin combined with a farnesyl-transferase inhibitor.
Biochemical pharmacology 2003;65(3):423-33.
2003: Grégoire Prevost; Marie-Christine Brezak; Françoise Goubin; Odile Mondesert; Marie-Odile Galcera; Muriel Quaranta; Frédéric Alby; Olivier Lavergne; BERNARD DUCOMMUN
Inhibitors of the CDC25 phosphatases.
Progress in cell cycle research 2003;5():225-34.
2001: Grégoire Prevost; Anne Pradines; Marie-Christine Brezak; Marie O Lonchampt; Isabelle Viossat; Isabelle Ader; Christine Toulas; Philip G Kasprzyk; T Gordon; Gilles FAVRE; B Morgan
Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228.
International journal of cancer. Journal international du cancer 2001;91(5):718-22.
1999: Grégoire Prevost; Anne Pradines; Isabelle Viossat; Marie-Christine Brezak; K Miquel; Marie O Lonchampt; Philip G Kasprzyk; Gilles FAVRE; Bernadette Pignol; C Le Breton; J Dong; B Morgan
Inhibition of human tumor cell growth in vitro and in vivo by a specific inhibitor of human farnesyltransferase: BIM-46068.
International journal of cancer. Journal international du cancer 1999;83(2):283-7.

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