Toshihiko Yada

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Maejima Yuko; Sedbazar Udval; Suyama Shigetomo; Kohno Daisuke; Onaka Tatsushi; Takano Eisuke; Yoshida Natsu; Koike Masato; Uchiyama Yasuo; Fujiwara Ken; Yashiro Takashi; Horvath Tamas L; Dietrich Marcelo O; Tanaka Shigeyasu; Dezaki Katsuya; Oh-I Shinsuke; Hashimoto Koushi; Shimizu Hiroyuki; Nakata Masanori; Mori Masatomo; Yada Toshihiko
Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway.
Yoshida Masashi; Dezaki Katsuya; Yamato Shiho; Aoki Atsushi; Sugawara Hitoshi; Toyoshima Hideo; Ishikawa San-e; Kawakami Masanobu; Nakata Masanori; Yada Toshihiko; Kakei Masafumi
Regulation of voltage-gated K+ channels by glucose metabolism in pancreatic beta-cells.
Suyama Shigetomo; Takano Eisuke; Iwasaki Yusaku; Nakata Masanori; Yada Toshihiko
[Roles and functional interplay of the gut, brain stem, hypothalamus and limbic system in regulation of feeding]

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2009: Maejima Yuko; Sedbazar Udval; Suyama Shigetomo; Kohno Daisuke; Onaka Tatsushi; Takano Eisuke; Yoshida Natsu; Koike Masato; Uchiyama Yasuo; Fujiwara Ken; Yashiro Takashi; Horvath Tamas L; Dietrich Marcelo O; Tanaka Shigeyasu; Dezaki Katsuya; Oh-I Shinsuke; Hashimoto Koushi; Shimizu Hiroyuki; Nakata Masanori; Mori Masatomo; Yada Toshihiko
Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway.
Cell metabolism 2009;10(5):355-65.
2009: Yoshida Masashi; Dezaki Katsuya; Yamato Shiho; Aoki Atsushi; Sugawara Hitoshi; Toyoshima Hideo; Ishikawa San-e; Kawakami Masanobu; Nakata Masanori; Yada Toshihiko; Kakei Masafumi
Regulation of voltage-gated K+ channels by glucose metabolism in pancreatic beta-cells.
FEBS letters 2009;583(13):2225-30.
2009: Suyama Shigetomo; Takano Eisuke; Iwasaki Yusaku; Nakata Masanori; Yada Toshihiko
[Roles and functional interplay of the gut, brain stem, hypothalamus and limbic system in regulation of feeding]
Nippon rinsho. Japanese journal of clinical medicine 2009;67(2):277-86.
2008: Kohno Daisuke; Suyama Shigetomo; Yada Toshihiko
Leptin transiently antagonizes ghrelin and long-lastingly orexin in regulation of Ca2+ signaling in neuropeptide Y neurons of the arcuate nucleus.
World journal of gastroenterology : WJG 2008;14(41):6347-54.
2008: Koizumi Masaru; Yada Toshihiko
Sub-chronic stimulation of glucocorticoid receptor impairs and mineralocorticoid receptor protects cytosolic Ca2+ responses to glucose in pancreatic beta-cells.
The Journal of endocrinology 2008;197(2):221-9.
2008: Dezaki Katsuya; Sone Hedeyuki; Yada Toshihiko
Ghrelin is a physiological regulator of insulin release in pancreatic islets and glucose homeostasis.
Pharmacology & therapeutics 2008;118(2):239-49.
2008: Kohno Daisuke; Nakata Masanori; Maejima Yuko; Shimizu Hiroyuki; Sedbazar Udval; Yoshida Natsu; Dezaki Katsuya; Onaka Tatsushi; Mori Masatomo; Yada Toshihiko
Nesfatin-1 neurons in paraventricular and supraoptic nuclei of the rat hypothalamus coexpress oxytocin and vasopressin and are activated by refeeding.
Endocrinology 2008;149(3):1295-301.
2008: Yada Toshihiko; Dezaki Katsuya; Sone Hideyuki; Koizumi Masaru; Damdindorj Boldbaatar; Nakata Masanori; Kakei Masafumi
Ghrelin regulates insulin release and glycemia: physiological role and therapeutic potential.
Current diabetes reviews 2008;4(1):18-23.
2008: Kohno Daisuke; Sone Hideyuki; Minokoshi Yasuhiko; Yada Toshihiko
Ghrelin raises [Ca2+]i via AMPK in hypothalamic arcuate nucleus NPY neurons.
Biochemical and biophysical research communications 2008;366(2):388-92.
2008: Nakata Masanori; Yada Toshihiko
Cannabinoids inhibit insulin secretion and cytosolic Ca2+ oscillation in islet beta-cells via CB1 receptors.
Regulatory peptides 2008;145(1-3):49-53.
2008: Dezaki Katsuya; Kageyama Haruaki; Seki Mayumi; Shioda Seiji; Yada Toshihiko
Neuropeptide W in the rat pancreas: potentiation of glucose-induced insulin release and Ca2+ influx through L-type Ca2+ channels in beta-cells and localization in islets.
Regulatory peptides 2008;145(1-3):153-8.
2007: Iwasaki Hiroaki; Yada Toshihiko
Protein arginine methylation regulates insulin signaling in L6 skeletal muscle cells.
Biochemical and biophysical research communications 2007;364(4):1015-21.
2007: Dezaki Katsuya; Kakei Masafumi; Yada Toshihiko
Ghrelin uses Galphai2 and activates voltage-dependent K+ channels to attenuate glucose-induced Ca2+ signaling and insulin release in islet beta-cells: novel signal transduction of ghrelin.
Diabetes 2007;56(9):2319-27.
2007: Kohno Daisuke; Nakata Masanori; Maekawa Fumihiko; Fujiwara Ken; Maejima Yuko; Kuramochi Motoki; Shimazaki Takuya; Okano Hideyuki; Onaka Tatsushi; Yada Toshihiko
Leptin suppresses ghrelin-induced activation of neuropeptide Y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway.
Endocrinology 2007;148(5):2251-63.
2007: Fujiwara Ken; Maekawa Fumihiko; Dezaki Katsuya; Nakata Masanori; Yashiro Takashi; Yada Toshihiko
Oleic acid glucose-independently stimulates glucagon secretion by increasing cytoplasmic Ca2+ via endoplasmic reticulum Ca2+ release and Ca2+ influx in the rat islet alpha-cells.
Endocrinology 2007;148(5):2496-504.
2007: Fujiwara Ken; Maekawa Fumihiko; Kikuchi Motoshi; Takigami Shu; Yada Toshihiko; Yashiro Takashi
Expression of retinaldehyde dehydrogenase (RALDH)2 and RALDH3 but not RALDH1 in the developing anterior pituitary glands of rats.
Cell and tissue research 2007;328(1):129-35.
2007: Nakata Masanori; Okada Takashi; Ozawa Keiya; Yada Toshihiko
Resistin induces insulin resistance in pancreatic islets to impair glucose-induced insulin release.
Biochemical and biophysical research communications 2007;353(4):1046-51.
2007: Nakata Masanori; Yada Toshihiko
PACAP in the glucose and energy homeostasis: physiological role and therapeutic potential.
Current pharmaceutical design 2007;13(11):1105-12.
2006: Kohno Daisuke; Toriya Masako; Yada Toshihiko; Kurita Hideharu; Kuramochi Motoki
[Hypothalamic nuclei sense metabolic signals and regulate feeding]
Nippon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 9():91-7.
2006: Dezaki Katsuya; Sone Hideyuki; Koizumi Masaru; Nakata Masanori; Kakei Masafumi; Nagai Hideo; Hosoda Hiroshi; Kangawa Kenji; Yada Toshihiko
Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance.
Diabetes 2006;55(12):3486-93.
2006: Oomura Y; Hori N; Shiraishi T; Fukunaga K; Takeda H; Tsuji M; Matsumiya T; Ishibashi M; Aou S; Li X L; Kohno D; Uramura K; Sougawa H; Yada T; Wayner M J; Sasaki K
Leptin facilitates learning and memory performance and enhances hippocampal CA1 long-term potentiation and CaMK II phosphorylation in rats.
Peptides 2006;27(11):2738-49.
2006: Maekawa F; Fujiwara K; Kohno D; Kuramochi M; Kurita H; Yada T
Young adult-specific hyperphagia in diabetic Goto-kakizaki rats is associated with leptin resistance and elevation of neuropeptide Y mRNA in the arcuate nucleus.
Journal of neuroendocrinology 2006;18(10):748-56.
2006: Nakata M; Nagasaka S; Kusaka I; Matsuoka H; Ishibashi S; Yada T
Effects of statins on the adipocyte maturation and expression of glucose transporter 4 (SLC2A4): implications in glycaemic control.
Diabetologia 2006;49(8):1881-92.
2006: Kuramochi Motoki; Onaka Tatsushi; Kohno Daisuke; Kato Satoshi; Yada Toshihiko
Galanin-like peptide stimulates food intake via activation of neuropeptide Y neurons in the hypothalamic dorsomedial nucleus of the rat.
Endocrinology 2006;147(4):1744-52.
2006: Maekawa Fumihiko; Fujiwara Ken; Tsukahara Shinji; Yada Toshihiko
Pituitary adenylate cyclase-activating polypeptide neurons of the ventromedial hypothalamus project to the midbrain central gray.
Neuroreport 2006;17(2):221-4.
2005: Nakata Masanori; Maruyama Ikuro; Yada Toshihiko
Leptin potentiates ADP-induced [Ca(2+)](i) increase via JAK2 and tyrosine kinases in a megakaryoblast cell line.
Diabetes research and clinical practice 2005;70(3):209-16.
2005: Muroya Shinji; Funahashi Hisayuki; Uramura Kazuhide; Shioda Seiji; Yada Toshihiko
Gamma aminobutyric acid regulates glucosensitive neuropeptide Y neurons in arcuate nucleus via A/B receptors.
Neuroreport 2005;16(9):897-901.
2005: Kuramochi Motoki; Kohno Daisuke; Onaka Tatsushi; Kato Satoshi; Yada Toshihiko
Galanin-like peptide and ghrelin increase cytosolic Ca2+ in neurons containing growth hormone-releasing hormone in the arcuate nucleus.
Regulatory peptides 2005;126(1-2):85-9.
2005: Onaka Tatsushi; Kuramochi Motoki; Saito Jun; Ueta Yoichi; Yada Toshihiko
Galanin-like peptide stimulates vasopressin, oxytocin and adrenocorticotropic hormone release in rats.
Neuroreport 2005;16(3):243-7.
2004: Dezaki Katsuya; Hosoda Hiroshi; Kakei Masafumi; Hashiguchi Suzuko; Watanabe Masatomo; Kangawa Kenji; Yada Toshihiko
Endogenous ghrelin in pancreatic islets restricts insulin release by attenuating Ca2+ signaling in beta-cells: implication in the glycemic control in rodents.
Diabetes 2004;53(12):3142-51.
2004: Yamada Hiroyuki; Watanabe Masahiro; Yada Toshihiko
Cytosolic Ca2+ responses to sub-picomolar and nanomolar PACAP in pancreatic beta-cells are mediated by VPAC2 and PAC1 receptors.
Regulatory peptides 2004;123(1-3):147-53.
2004: Kakei Masafumi; Dezaki Katsuya; Yada Toshihiko
[Methods for preparation and functional analysis of islet beta-cells]
Nippon yakurigaku zasshi. Folia pharmacologica Japonica 2004;124(5):345-52.
2004: Nakata Masanori; Kohno Daisuke; Shintani Norihito; Nemoto Yuriko; Hashimoto Hitoshi; Baba Akemichi; Yada Toshihiko
PACAP deficient mice display reduced carbohydrate intake and PACAP activates NPY-containing neurons in the rat hypothalamic arcuate nucleus.
Neuroscience letters 2004;370(2-3):252-6.
2004: Dezaki Katsuya; Yada Toshihiko
[Ghrelin in the regulation of glucose and lipid metabolism]
Nippon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 9():388-91.
2004: Nakata Masanori; Yada Toshihiko
[Physiological and therapeutic roles of PACAP in glucose metabolism and diabetes]
Nippon yakurigaku zasshi. Folia pharmacologica Japonica 2004;123(4):267-73.
2004: Muroya Shinji; Funahashi Hisayuki; Yamanaka Akihiro; Kohno Daisuke; Uramura Kazuhide; Nambu Tadahiro; Shibahara Megumi; Kuramochi Motoki; Takigawa Morikuni; Yanagisawa Masashi; Sakurai Takeshi; Shioda Seiji; Yada Toshihiko
Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose-responsive neurons to regulate Ca 2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus.
The European journal of neuroscience 2004;19(6):1524-34.
2003: Nakata Masanori; Yada Toshihiko
Endocrinology: nitric oxide-mediated insulin secretion in response to citrulline in islet beta-cells.
Pancreas 2003;27(3):209-13.
2003: Sasa Masashi; Nishi Akinori; Kobayashi Kazuto; Sano Hiromi; Momiyama Toshihiko; Uramura Kazuhide; Yada Toshihiko; Mori Norio; Suzuki Katsuaki; Minabe Yoshio
[Regulation of psychomotor functions by dopamine: integration of various approaches]
Nippon yakurigaku zasshi. Folia pharmacologica Japonica 2003;122(3):215-25.
2003: Kohno Daisuke; Gao Hong-Zhi; Muroya Shinji; Kikuyama Sakae; Yada Toshihiko
Ghrelin directly interacts with neuropeptide-Y-containing neurons in the rat arcuate nucleus: Ca2+ signaling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin.
Diabetes 2003;52(4):948-56.
2002: Kakei Masafumi; Yada Toshihiko; Nakagawa Atsushi; Nakabayashi Hajime
Glucagon-like peptide-1 evokes action potentials and increases cytosolic Ca2+ in rat nodose ganglion neurons.
Autonomic neuroscience : basic & clinical 2002;102(1-2):39-44.
2002: Kakei Masafumi; Nakazaki Mitsuhiro; Yaekura Kazuro; Yanagida Kazuhiro; Yada Toshihiko
[Impairment of islet beta-cell metabolism and insulin secretion]
Nippon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 7():504-10.
2002: Kakei Masafumi; Koriyama Nobuyuki; Nakata Masanori; Dezaki Katsuya; Yada Tosihiko
[Ion channel mechanisms in insulin secretion]
Nippon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 7():180-9.
2002: Zhu Lingling; Onaka Tatsushi; Sakurai Takeshi; Yada Toshihiko
Activation of orexin neurones after noxious but not conditioned fear stimuli in rats.
Neuroreport 2002;13(10):1351-3.
2002: Nakazaki Mitsuhiro; Kakei Masafumi; Ishihara Hisamitsu; Koriyama Nobuyuki; Hashiguchi Hiroshi; Aso Katsumi; Fukudome Michiyo; Oka Yoshitomo; Yada Toshihiko; Tei Chuwa
Association of upregulated activity of K(ATP) channels with impaired insulin secretion in UCP1-expressing insulinoma cells.
The Journal of physiology 2002;540(Pt 3):781-9.
2002: Yanagida Kazuhiro; Yaekura Kazuro; Arima Terukatsu; Yada Toshihiko
Glucose-insensitivity induced by Ca(2+) toxicity in islet beta-cells and its prevention by PACAP.
Peptides 2002;23(1):135-42.
2002: Date Yukari; Nakazato Masamitsu; Hashiguchi Suzuko; Dezaki Katsuya; Mondal Muhtashan S; Hosoda Hiroshi; Kojima Masayasu; Kangawa Kenji; Arima Terukatsu; Matsuo Hisayuki; Yada Toshihiko; Matsukura Shigeru
Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion.
Diabetes 2002;51(1):124-9.
2001: Muroya S; Uramura K; Sakurai T; Takigawa M; Yada T
Lowering glucose concentrations increases cytosolic Ca2+ in orexin neurons of the rat lateral hypothalamus.
Neuroscience letters 2001;309(3):165-8.
2001: Uramura K; Funahashi H; Muroya S; Shioda S; Takigawa M; Yada T
Orexin-a activates phospholipase C- and protein kinase C-mediated Ca2+ signaling in dopamine neurons of the ventral tegmental area.
Neuroreport 2001;12(9):1885-9.
2001: Koriyama N; Kakei M; Nakazaki M; Yaekura K; Hashiguchi H; Aso K; Fukudome M; Yada T; Ito S; Tei C
Free radical-mediated tolbutamide desensitization of K+ATP channels in rat pancreatic beta-cells.
Endocrine journal 2001;48(3):337-44.
2001: Hashiguchi S; Yada T; Arima T
A new hypoglycemic agent, JTT-608, evokes protein kinase A-mediated Ca(2+) signaling in rat islet beta-cells: strict regulation by glucose, link to insulin release, and cooperation with glucagon-like peptide-1(7-36)amide and pituitary adenylate cyclase-activating polypeptide.
The Journal of pharmacology and experimental therapeutics 2001;296(1):22-30.
2000: Koriyama N; Kakei M; Nakazaki M; Yaekura K; Ichinari K; Gong Q; Morimitsu S; Yada T; Tei C
PIP2 and ATP cooperatively prevent cytosolic Ca2+-induced modification of ATP-sensitive K+ channels in rat pancreatic beta-cells.
Diabetes 2000;49(11):1830-9.
2000: Uramura K; Yada T; Muroya S; Takigawa M
Ca2+ oscillations in response to methamphetamine in dopamine neurons of the ventral tegmental area in rats subchronically treated with this drug.
Annals of the New York Academy of Sciences 2000;914():316-22.
2000: Nakazaki M; Kakei M; Yaekura K; Koriyama N; Morimitsu S; Ichinari K; Yada T; Tei C
Diverse effects of hydrogen peroxide on cytosolic Ca2+ homeostasis in rat pancreatic beta-cells.
Cell structure and function 2000;25(3):187-93.
2000: Uramura K; Yada T; Muroya S; Shioda S; Shiratani T; Takigawa M
Methamphetamine induces cytosolic Ca2+ oscillations in the VTA dopamine neurons.
Neuroreport 2000;11(5):1057-61.
2000: Arahira S; Kusao M; Shioda S; Yada T
PACAP activates pancreatic alpha-cells in a glucose independent manner.
Annals of the New York Academy of Sciences 2000;921():438-42.
2000: Yada T; Sakurada M; Filipsson K; Kikuchi M; Ahrén B
Intraperitoneal PACAP administration decreases blood glucose in GK rats, and in normal and high fat diet mice.
Annals of the New York Academy of Sciences 2000;921():259-63.
1999: Nakata M; Uto N; Maruyama I; Yada T
Nitric oxide induces apoptosis via Ca2+-dependent processes in the pancreatic beta-cell line MIN6.
Cell structure and function 1999;24(6):451-5.
1999: Muroya S; Yada T; Shioda S; Takigawa M
Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y.
Neuroscience letters 1999;264(1-3):113-6.
1999: Yada T; Nakata M; Shiraishi T; Kakei M
Inhibition by simvastatin, but not pravastatin, of glucose-induced cytosolic Ca2+ signalling and insulin secretion due to blockade of L-type Ca2+ channels in rat islet beta-cells.
British journal of pharmacology 1999;126(5):1205-13.
1999: Nakata M; Yada T; Soejima N; Maruyama I
Leptin promotes aggregation of human platelets via the long form of its receptor.
Diabetes 1999;48(2):426-9.
1999: Nakata M; Shioda S; Oka Y; Maruyama I; Yada T
Insulinotropin PACAP potentiates insulin-stimulated glucose uptake in 3T3 L1 cells.
Peptides 1999;20(8):943-8.
1998: Yada T; Sakurada M; Nakata M; Shioda S; Yaekura K; Kikuchi M
Autocrine action of PACAP in islets augments glucose-induced insulin secretion.
Annals of the New York Academy of Sciences 1998;865():451-7.
1998: Yaekura K; Yanagida K; Yada T
PACAP and GLP-1 protect islet beta-cells against Ca2+ toxicity induced by high K+.
Annals of the New York Academy of Sciences 1998;865():445-50.
1998: Nakazaki M; Ishihara H; Kakei M; Inukai K; Asano T; Miyazaki J I; Tanaka H; Kikuchi M; Yada T; Oka Y
Repetitive mitochondrial Ca2+ signals synchronize with cytosolic Ca2+ oscillations in the pancreatic beta-cell line, MIN6.
Diabetologia 1998;41(3):279-86.
1998: Yaekura K; Yada T
[Ca2+]i-reducing action of cAMP in rat pancreatic beta-cells: involvement of thapsigargin-sensitive stores.
The American journal of physiology 1998;274(2 Pt 1):C513-21.
1997: Yada T; Sakurada M; Ishihara H; Nakata M; Shioda S; Yaekura K; Hamakawa N; Yanagida K; Kikuchi M; Oka Y
Pituitary adenylate cyclase-activating polypeptide (PACAP) is an islet substance serving as an intra-islet amplifier of glucose-induced insulin secretion in rats.
The Journal of physiology 1997;505 ( Pt 2)():319-28.
1997: Yada T; Nakata M
[Molecular mechanisms for impaired insulin secretion in NIDDM]
Nippon rinsho. Japanese journal of clinical medicine 1997;55 Suppl():320-7.
1997: Nakata M; Yada T; Nakagawa S; Kobayashi K; Maruyama I
Citrulline-argininosuccinate-arginine cycle coupled to Ca2+-signaling in rat pancreatic beta-cells.
Biochemical and biophysical research communications 1997;235(3):619-24.
1997: Fujitani S; Okazaki K; Yada T
The ability of a new hypoglycaemic agent, A-4166, compared to sulphonylureas, to increase cytosolic Ca2+ in pancreatic beta-cells under metabolic inhibition.
British journal of pharmacology 1997;120(7):1191-8.
1997: Yaekura K; Nakata M; Tanaka H; Yada T
Cyclic AMP, a mediator of GLP-1, acts in concert with glucose and tolbutamide to increase cytosolic Ca2+ in pancreatic B-cells.
Advances in experimental medicine and biology 1997;426():211-6.
1997: Yada T; Sakurada M; Nakata M; Yaekura K; Kikuchi M
PACAP as low as 10(-13) M raises cytosolic Ca2+ activity in pancreatic B-cells by augmenting Ca2+ influx through L-type Ca2+ channels to trigger insulin release.
Advances in experimental medicine and biology 1997;426():165-71.
1997: Yada T
Extracellular messages for pancreatic B-cells.
Advances in experimental medicine and biology 1997;426():103-12.
1997: Yada T; Nakata M; Yaekura K
Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates insulin secretion in islets and potentiates glucose-transport in adipocytes.
The Japanese journal of physiology 1997;47 Suppl 1():S27.
1997: Kakei M; Nakazaki M; Koriyama N; Yaekura K; Ichinari K; Morimitsu S; Tanaka H; Yada T
Free-radical mediated cellular regulation in pancreatic beta-cells.
The Japanese journal of physiology 1997;47 Suppl 1():S7-8.
1996: Yada T; Sakurada M; Nakata M; Ihida K; Yaekura K; Shioda S; Kikuchi M
Current status of PACAP as a regulator of insulin secretion in pancreatic islets.
Annals of the New York Academy of Sciences 1996;805():329-40; discussion 341-2.
1996: Yaekura K; Kakei M; Yada T
cAMP-signaling pathway acts in selective synergism with glucose or tolbutamide to increase cytosolic Ca2+ in rat pancreatic beta-cells.
Diabetes 1996;45(3):295-301.
1995: Yada T; Hamakawa N; Yaekura K
Two distinct modes of Ca2+ signalling by ACh in rat pancreatic beta-cells: concentration, glucose dependence and Ca2+ origin.
The Journal of physiology 1995;488 ( Pt 1)():13-24.
1995: Hamakawa N; Yada T
Interplay of glucose-stimulated Ca2+ sequestration and acetylcholine-induced Ca2+ release at the endoplasmic reticulum in rat pancreatic beta-cells.
Cell calcium 1995;17(1):21-31.
1995: Aizawa T; Yada T; Asanuma N; Sato Y; Ishihara F; Hamakawa N; Yaekura K; Hashizume K
Effects of thapsigargin, an intracellular CA2+ pump inhibitor, on insulin release by rat pancreatic B-cell.
Life sciences 1995;57(14):1375-81.
1994: Nakahara K; Yada T; Kuriyama M; Osame M
Cytosolic Ca2+ increase and cell damage in L6 rat myoblasts by HMG-CoA reductase inhibitors.
Biochemical and biophysical research communications 1994;202(3):1579-85.
1994: Fujitani S; Yada T
A novel D-phenylalanine-derivative hypoglycemic agent A-4166 increases cytosolic free Ca2+ in rat pancreatic beta-cells by stimulating Ca2+ influx.
Endocrinology 1994;134(3):1395-400.
1994: Yada T; Sakurada M; Ihida K; Nakata M; Murata F; Arimura A; Kikuchi M
Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells.
The Journal of biological chemistry 1994;269(2):1290-3.
1993: Yada T; Itoh K; Nakata M
Glucagon-like peptide-1-(7-36)amide and a rise in cyclic adenosine 3',5'-monophosphate increase cytosolic free Ca2+ in rat pancreatic beta-cells by enhancing Ca2+ channel activity.
Endocrinology 1993;133(4):1685-92.
1993: Yada T; Vigh S; Arimura A
Pituitary adenylate cyclase activating polypeptide (PACAP) increases cytosolic-free calcium concentration in folliculo-stellate cells and somatotropes of rat pituitary.
Peptides 1993;14(2):235-9.
1993: Yada T; Itoh K; Kakei M; Tanaka H
Glucose metabolism by rat pancreatic beta-cells produces dual change in cytosolic Ca2+.
The Japanese journal of physiology 1993;43 Suppl 1():S115-8.
1992: Yada T; Kakei M; Tanaka H
Single pancreatic beta-cells from normal rats exhibit an initial decrease and subsequent increase in cytosolic free Ca2+ in response to glucose.
Cell calcium 1992;13(1):69-76.
1991: Nakamura H; Yada T; Saheki T; Noda T; Nakagawa S
L-argininosuccinate modulates L-glutamate response in acutely isolated cerebellar neurons of immature rat.
Brain research 1991;539(2):312-5.
1990: Sorimachi M; Yada T
[Secretory mechanism of biologically active substances]
Nippon seirigaku zasshi. Journal of the Physiological Society of Japan 1990;52(5):165-77.
1989: Sorimachi M; Yamagami K; Yada T; Nishimura S
Spontaneous and secretagogue-induced changes in cytosolic free Ca concentration measured by microfluorimetry with fura-2 on single bovine adrenal chromaffin cells.
The Japanese journal of physiology 1989;39(5):687-701.
1988: Sorimachi M; Nishimura S; Yamagami K; Yada T
Fluoroaluminates stimulate histamine secretion in the digitonin-permeabilized rat mast cells.
The Japanese journal of physiology 1988;38(2):227-32.

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