Hideo Yagita

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Yamato I; Sho M; Nomi T; Akahori T; Shimada K; Hotta K; Kanehiro H; Konishi N; Yagita H; Nakajima Y
Clinical importance of B7-H3 expression in human pancreatic cancer.
Knoop Kathryn A; Kumar Nachiket; Butler Betsy R; Sakthivel Senthilkumar K; Taylor Rebekah T; Nochi Tomonori; Akiba Hisaya; Yagita Hideo; Kiyono Hiroshi; Williams Ifor R
RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium.
Wafula Paul Ojiambo; Teles Ana; Schumacher Anne; Pohl Kerstin; Yagita Hideo; Volk Hans-Dieter; Zenclussen Ana Claudia
PD-1 but not CTLA-4 blockage abrogates the protective effect of regulatory T cells in a pregnancy murine model.

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All Publications

2009: Yamato I; Sho M; Nomi T; Akahori T; Shimada K; Hotta K; Kanehiro H; Konishi N; Yagita H; Nakajima Y
Clinical importance of B7-H3 expression in human pancreatic cancer.
British journal of cancer 2009;101(10):1709-16.
2009: Knoop Kathryn A; Kumar Nachiket; Butler Betsy R; Sakthivel Senthilkumar K; Taylor Rebekah T; Nochi Tomonori; Akiba Hisaya; Yagita Hideo; Kiyono Hiroshi; Williams Ifor R
RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(9):5738-47.
2009: Wafula Paul Ojiambo; Teles Ana; Schumacher Anne; Pohl Kerstin; Yagita Hideo; Volk Hans-Dieter; Zenclussen Ana Claudia
PD-1 but not CTLA-4 blockage abrogates the protective effect of regulatory T cells in a pregnancy murine model.
American journal of reproductive immunology (New York, N.Y. : 1989) 2009;62(5):283-92.
2009: Kametani Yoshie; Suzuki Daisuke; Kohu Kazuyoshi; Satake Masanobu; Suemizu Hiroshi; Sasaki Erika; Ito Toshio; Tamaoki Norikazu; Mizushima Tomoko; Ozawa Manabu; Tani Kenzaburo; Kito Mitsuaki; Arai Hideo; Koyanagi Akemi; Yagita Hideo; Habu Sonoko
Development of monoclonal antibodies for analyzing immune and hematopoietic systems of common marmoset.
Experimental hematology 2009;37(11):1318-29.
2009: Okudaira Keisuke; Hokari Ryota; Tsuzuki Yoshikazu; Okada Yoshikiyo; Komoto Shunsuke; Watanabe Chikako; Kurihara Chie; Kawaguchi Atsushi; Nagao Shigeaki; Azuma Miyuki; Yagita Hideo; Miura Soichiro
Blockade of B7-H1 or B7-DC induces an anti-tumor effect in a mouse pancreatic cancer model.
International journal of oncology 2009;35(4):741-9.
2009: Allam Atef; Conze Dietrich B; Giardino Torchia Maria Letizia; Munitic Ivana; Yagita Hideo; Sowell Ryan T; Marzo Amanda L; Ashwell Jonathan D
The CD8+ memory T-cell state of readiness is actively maintained and reversible.
Blood 2009;114(10):2121-30.
2009: Nguyen Quang-Tam; Ju Seong-A; Park Sang-Min; Lee Sang-Chul; Yagita Hideo; Lee In Hee; Kim Byung-Sam
Blockade of CD137 signaling counteracts polymicrobial sepsis induced by cecal ligation and puncture.
Infection and immunity 2009;77(9):3932-8.
2009: Shanker Anil; Brooks Alan D; Jacobsen Kristen M; Wine John W; Wiltrout Robert H; Yagita Hideo; Sayers Thomas J
Antigen presented by tumors in vivo determines the nature of CD8+ T-cell cytotoxicity.
Cancer research 2009;69(16):6615-23.
2009: Poonia Bhawna; Salvato Maria S; Yagita Hideo; Maeda Toshihiro; Okumura Ko; Pauza C David
Treatment with anti-FasL antibody preserves memory lymphocytes and virus-specific cellular immunity in macaques challenged with simian immunodeficiency virus.
Blood 2009;114(6):1196-204.
2009: Molinero Luciana Lorena; Wang Ying; Zhou Ping; Yagita Hideo; Alegre Maria-Luisa
Fas mediates cardiac allograft acceptance in mice with impaired T-cell-intrinsic NF-kappaB signaling.
Transplant international : official journal of the European Society for Organ Transplantation 2009;22(8):845-52.
2009: Tchorsh-Yutsis Dalit; Hecht Gil; Aronovich Anna; Shezen Elias; Klionsky Yael; Rosen Chava; Bitcover Rivka; Eventov-Friedman Smadar; Katchman Helena; Cohen Sivan; Tal Orna; Milstein Oren; Yagita Hideo; Blazar Bruce R; Reisner Yair
Pig embryonic pancreatic tissue as a source for transplantation in diabetes: transient treatment with anti-LFA1, anti-CD48, and FTY720 enables long-term graft maintenance in mice with only mild ongoing immunosuppression.
Diabetes 2009;58(7):1585-94.
2009: Yuan Xueli; Ansari M Javeed; D'Addio Francesca; Paez-Cortez Jesus; Schmitt Isabella; Donnarumma Michela; Boenisch Olaf; Zhao Xiaozhi; Popoola Joyce; Clarkson Michael R; Yagita Hideo; Akiba Hisaya; Freeman Gordon J; Iacomini John; Turka Laurence A; Glimcher Laurie H; Sayegh Mohamed H
Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(26):10734-9.
2009: Lee Suk-young; Kumano Keiki; Nakazaki Kumi; Sanada Masashi; Matsumoto Akihiko; Yamamoto Go; Nannya Yasuhito; Suzuki Ritsuro; Ota Satoshi; Ota Yasunori; Izutsu Koji; Sakata-Yanagimoto Mamiko; Hangaishi Akira; Yagita Hideo; Fukayama Masashi; Seto Masao; Kurokawa Mineo; Ogawa Seishi; Chiba Shigeru
Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma.
Cancer science 2009;100(5):920-6.
2009: Haraguchi Kyoko; Suzuki Takahiro; Koyama Noriko; Kumano Keiki; Nakahara Fumio; Matsumoto Akihiko; Yokoyama Yasuhisa; Sakata-Yanagimoto Mamiko; Masuda Shigeo; Takahashi Tsuyoshi; Kamijo Aki; Takahashi Koki; Takanashi Minoko; Okuyama Yoshiki; Yasutomo Koji; Sakano Seiji; Yagita Hideo; Kurokawa Mineo; Ogawa Seishi; Chiba Shigeru
Notch activation induces the generation of functional NK cells from human cord blood CD34-positive cells devoid of IL-15.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6168-78.
2009: Totsuka Teruji; Kanai Takanori; Nemoto Yasuhiro; Tomita Takayuki; Okamoto Ryuichi; Tsuchiya Kiichiro; Nakamura Tetsuya; Sakamoto Naoya; Akiba Hisaya; Okumura Ko; Yagita Hideo; Watanabe Mamoru
RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T cells in chronic colitis.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6079-87.
2009: Yamada Jun; Hamuro Junji; Fukushima Atsuki; Ohteki Toshiaki; Terai Kazuto; Iwakura Yoichiro; Yagita Hideo; Kinoshita Shigeru
MHC-matched corneal allograft rejection in an IFN-gamma/IL-17-independent manner in C57BL/6 mice.
Investigative ophthalmology & visual science 2009;50(5):2139-46.
2009: Usui Yoshihiko; Takeuchi Masaru; Hattori Takaaki; Okunuki Yoko; Nagasawa Kazumi; Kezuka Takeshi; Okumura Ko; Yagita Hideo; Akiba Hisaya; Goto Hiroshi
Suppression of experimental autoimmune uveoretinitis by regulatory dendritic cells in mice.
Archives of ophthalmology 2009;127(4):514-9.
2009: Fuse Shinichiro; Tsai Ching-Yi; Molloy Michael J; Allie S Rameeza; Zhang Weijun; Yagita Hideo; Usherwood Edward J
Recall responses by helpless memory CD8+ T cells are restricted by the up-regulation of PD-1.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(7):4244-54.
2009: Nakayama Masafumi; Akiba Hisaya; Takeda Kazuyoshi; Kojima Yuko; Hashiguchi Masaaki; Azuma Miyuki; Yagita Hideo; Okumura Ko
Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation.
Blood 2009;113(16):3821-30.
2009: Yamanda Shinsuke; Ebihara Satoru; Asada Masanori; Okazaki Tatsuma; Niu Kaijun; Ebihara Takae; Koyanagi Akemi; Yamaguchi Noriko; Yagita Hideo; Arai Hiroyuki
Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockade.
Blood 2009;113(15):3631-9.
2009: Onizawa Michio; Nagaishi Takashi; Kanai Takanori; Nagano Ken-ichi; Oshima Shigeru; Nemoto Yasuhiro; Yoshioka Atsushi; Totsuka Teruji; Okamoto Ryuichi; Nakamura Tetsuya; Sakamoto Naoya; Tsuchiya Kiichiro; Aoki Kazuhiro; Ohya Keiichi; Yagita Hideo; Watanabe Mamoru
Signaling pathway via TNF-alpha/NF-kappaB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis.
American journal of physiology. Gastrointestinal and liver physiology 2009;296(4):G850-9.
2009: Kijima Mika; Iwata Akiko; Maekawa Yoichi; Uehara Hisanori; Izumi Keisuke; Kitamura Akiko; Yagita Hideo; Chiba Shigeru; Shiota Hiroshi; Yasutomo Koji
Jagged1 suppresses collagen-induced arthritis by indirectly providing a negative signal in CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3566-72.
2009: Parekh Vrajesh V; Lalani Saif; Kim Sungjune; Halder Ramesh; Azuma Miyuki; Yagita Hideo; Kumar Vipin; Wu Lan; Kaer Luc Van
PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(5):2816-26.
2009: Cheuk Adam T C; Wells James W; Chan Lucas; Westwood Nigel B; Berger Stuart A; Yagita Hideo; Okumura Ko; Farzaneh Farzin; Mufti Ghulam J; Guinn Barbara-Ann
Anti-tumor immunity in a model of acute myeloid leukemia.
Leukemia & lymphoma 2009;50(3):447-54.
2009: Sekine Chiyoko; Moriyama Yuko; Koyanagi Akemi; Koyama Noriko; Ogata Hideko; Okumura Ko; Yagita Hideo
Differential regulation of splenic CD8- dendritic cells and marginal zone B cells by Notch ligands.
International immunology 2009;21(3):295-301.
2009: Persson Catrine M; Lambert Henrik; Vutova Polya P; Dellacasa-Lindberg Isabel; Nederby Joanna; Yagita Hideo; Ljunggren Hans-Gustaf; Grandien Alf; Barragan Antonio; Chambers Benedict J
Transmission of Toxoplasma gondii from infected dendritic cells to natural killer cells.
Infection and immunity 2009;77(3):970-6.
2009: Tamayo Esther; Postigo Jorge; Del Giudice Giuseppe; Rappuoli Rino; Benito Adalberto; Yagita Hideo; Merino Ramón; Merino Jesús
Involvement of the intrinsic and extrinsic cell-death pathways in the induction of apoptosis of mature lymphocytes by the Escherichia coli heat-labile enterotoxin.
European journal of immunology 2009;39(2):439-46.
2009: Nakano Nobuhiro; Nishiyama Chiharu; Yagita Hideo; Koyanagi Akemi; Akiba Hisaya; Chiba Shigeru; Ogawa Hideoki; Okumura Ko
Notch signaling confers antigen-presenting cell functions on mast cells.
The Journal of allergy and clinical immunology 2009;123(1):74-81.e1.
2009: Kawamura Toshihiko; Takeda Kazuyoshi; Kaneda Hiroshi; Matsumoto Hiroaki; Hayakawa Yoshihiro; Raulet David H; Ikarashi Yoshinori; Kronenberg Mitchell; Yagita Hideo; Kinoshita Katsuyuki; Abo Toru; Okumura Ko; Smyth Mark J
NKG2A inhibits invariant NKT cell activation in hepatic injury.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(1):250-8.
2009: Yadav Deepak; Hill Natasha; Yagita Hideo; Azuma Miyuki; Sarvetnick Nora
Altered availability of PD-1/PD ligands is associated with the failure to control autoimmunity in NOD mice.
Cellular immunology 2009;258(2):161-71.
2009: Sumi Tamaki; Ishida Waka; Mittler Robert S; Yagita Hideo; Taguchi Osamu; Fukushima Atsuki
Regulatory T cells participate in 4-1BB-mediated suppression of experimental allergic conjunctivitis.
International archives of allergy and immunology 2009;148(4):305-10.
2008: Chang Woo-Sung; Kim Ji-Yeon; Kim Yeon-Jeong; Kim Yun-Sun; Lee Jung-Mi; Azuma Miyuki; Yagita Hideo; Kang Chang-Yuil
Cutting edge: Programmed death-1/programmed death ligand 1 interaction regulates the induction and maintenance of invariant NKT cell anergy.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(10):6707-10.
2008: Roux Stephan; Apetoh Lionel; Chalmin Fanny; Ladoire Sylvain; Mignot Grégoire; Puig Pierre-Emmanuel; Lauvau Gregoire; Zitvogel Laurence; Martin François; Chauffert Bruno; Yagita Hideo; Solary Eric; Ghiringhelli François
CD4+CD25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer.
The Journal of clinical investigation 2008;118(11):3751-61.
2008: Nemoto Yasuhiro; Kanai Takanori; Tohda Shuji; Totsuka Teruji; Okamoto Ryuichi; Tsuchiya Kiichiro; Nakamura Tetsuya; Sakamoto Naoya; Fukuda Tetsuya; Miura Osamu; Yagita Hideo; Watanabe Mamoru
Negative feedback regulation of colitogenic CD4+ T cells by increased granulopoiesis.
Inflammatory bowel diseases 2008;14(11):1491-503.
2008: Stagg John; Sharkey Janelle; Pommey Sandra; Young Richard; Takeda Kazuyoshi; Yagita Hideo; Johnstone Ricky W; Smyth Mark J
Antibodies targeted to TRAIL receptor-2 and ErbB-2 synergize in vivo and induce an antitumor immune response.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(42):16254-9.
2008: Maekawa Yoichi; Minato Yoshiaki; Ishifune Chieko; Kurihara Takeshi; Kitamura Akiko; Kojima Hidefumi; Yagita Hideo; Sakata-Yanagimoto Mamiko; Saito Toshiki; Taniuchi Ichiro; Chiba Shigeru; Sone Saburo; Yasutomo Koji
Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.
Nature immunology 2008;9(10):1140-7.
2008: Atarashi Koji; Nishimura Junichi; Shima Tatsuichiro; Umesaki Yoshinori; Yamamoto Masahiro; Onoue Masaharu; Yagita Hideo; Ishii Naoto; Evans Richard; Honda Kenya; Takeda Kiyoshi
ATP drives lamina propria T(H)17 cell differentiation.
Nature 2008;455(7214):808-12.
2008: Ito Akiko; Shimura Hideki; Nitahara Ayano; Tomiyama Katsuhiro; Ito Masaaki; Kanekura Takuro; Okumura Ko; Yagita Hideo; Kawai Kazuhiro
NK cells contribute to the skin graft rejection promoted by CD4+ T cells activated through the indirect allorecognition pathway.
International immunology 2008;20(10):1343-9.
2008: Saeki Kumiko; Yogiashi Yoshiko; Nakahara Masako; Nakamura Naoko; Matsuyama Satoko; Koyanagi Akemi; Yagita Hideo; Koyanagi Makoto; Kondo Yasushi; Yuo Akira
Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells.
Journal of cellular physiology 2008;217(1):261-80.
2008: Nagashima Osamu; Harada Norihiro; Usui Yoshihiko; Yamazaki Tomohide; Yagita Hideo; Okumura Ko; Takahashi Kazuhisa; Akiba Hisaya
B7-H3 contributes to the development of pathogenic Th2 cells in a murine model of asthma.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):4062-71.
2008: Sawada Taisuke; Nishiyama Chiharu; Kishi Takuma; Sasazuki Tomonari; Komazawa-Sakon Sachiko; Xue Xin; Piao Jiang-Hu; Ogata Hideko; Nakayama Jun-ichi; Taki Tomohiko; Hayashi Yasuhide; Watanabe Mamoru; Yagita Hideo; Okumura Ko; Nakano Hiroyasu
Fusion of OTT to BSAC results in aberrant up-regulation of transcriptional activity.
The Journal of biological chemistry 2008;283(39):26820-8.
2008: Delisle Jean-Sébastien; Gaboury Louis; Bélanger Marie-Pier; Tassé Eliane; Yagita Hideo; Perreault Claude
Graft-versus-host disease causes failure of donor hematopoiesis and lymphopoiesis in interferon-gamma receptor-deficient hosts.
Blood 2008;112(5):2111-9.
2008: Frew Ailsa J; Lindemann Ralph K; Martin Ben P; Clarke Christopher J P; Sharkey Janelle; Anthony Desiree A; Banks Kellie-Marie; Haynes Nicole M; Gangatirkar Pradnya; Stanley Kym; Bolden Jessica E; Takeda Kazuyoshi; Yagita Hideo; Secrist J Paul; Smyth Mark J; Johnstone Ricky W
Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(32):11317-22.
2008: Takeda Kazuyoshi; Kojima Yuko; Ikejima Kenichi; Harada Kenichi; Yamashina Shunhei; Okumura Kyoko; Aoyama Tomonori; Frese Steffen; Ikeda Hiroko; Haynes Nicole M; Cretney Erika; Yagita Hideo; Sueyoshi Noriyoshi; Sato Nobuhiro; Nakanuma Yasuni; Smyth Mark J; Okumura Ko
Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10895-900.
2008: Tseng Chih Wen; Monie Archana; Trimble Cornelia; Alvarez Ronald D; Huh Warner K; Buchsbaum Donald J; Straughn J Michael; Wang Mei-Cheng; Yagita Hideo; Hung Chien-Fu; Wu T-C
Combination of treatment with death receptor 5-specific antibody with therapeutic HPV DNA vaccination generates enhanced therapeutic anti-tumor effects.
Vaccine 2008;26(34):4314-9.
2008: Nakajima Akihito; Kurihara Hidetake; Yagita Hideo; Okumura Ko; Nakano Hiroyasu
Mitochondrial Extrusion through the cytoplasmic vacuoles during cell death.
The Journal of biological chemistry 2008;283(35):24128-35.
2008: Elyaman Wassim; Kivisäkk Pia; Reddy Jay; Chitnis Tanuja; Raddassi Khadir; Imitola Jaime; Bradshaw Elizabeth; Kuchroo Vijay K; Yagita Hideo; Sayegh Mohamed H; Khoury Samia J
Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis.
The American journal of pathology 2008;173(2):411-22.
2008: Sumi Tamaki; Ishida Waka; Ojima Ayako; Kajisako Minako; Sakanishi Tamami; Yagita Hideo; Fukushima Atsuki
CD27 and CD70 do not play a critical role in the development of experimental allergic conjunctivitis in mice.
Immunology letters 2008;119(1-2):91-6.
2008: Nakajima Hiroo; Mizuta Naruhiko; Fujiwara Ikuya; Sakaguchi Koichi; Ogata Hiromitsu; Magae Junji; Yagita Hideo; Koji Takehiko
Blockade of the Fas/Fas ligand interaction suppresses hepatocyte apoptosis in ischemia-reperfusion rat liver.
Apoptosis : an international journal on programmed cell death 2008;13(8):1013-21.
2008: Mikhailov Andrey; Sokolovskaya Alice; Yegutkin Gennady G; Amdahl Hanne; West Anne; Yagita Hideo; Lahesmaa Riitta; Thompson Linda F; Jalkanen Sirpa; Blokhin Dmitry; Eriksson John E
CD73 participates in cellular multiresistance program and protects against TRAIL-induced apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(1):464-75.
2008: Kohu Kazuyoshi; Yamabe Eiji; Matsuzawa Ayako; Onda Daisuke; Suemizu Hiroshi; Sasaki Erika; Tanioka Yoshikuni; Yagita Hideo; Suzuki Daisuke; Kametani Yoshie; Takai Toshiyuki; Toyoda Atsushi; Habu Sonoko; Satake Masanobu
Comparison of 30 immunity-related genes from the common marmoset with orthologues from human and mouse.
The Tohoku journal of experimental medicine 2008;215(2):167-80.
2008: Kanada Shunsuke; Nakano Nobuhiro; Potaczek Daniel P; Maeda Keiko; Shimokawa Naomi; Niwa Yusuke; Fukai Tatsuo; Sanak Marek; Szczeklik Andrew; Yagita Hideo; Okumura Ko; Ogawa Hideoki; Nishiyama Chiharu
Two different transcription factors discriminate the -315C>T polymorphism of the Fc epsilon RI alpha gene: binding of Sp1 to -315C and of a high mobility group-related molecule to -315T.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):8204-10.
2008: Moriyama Yuko; Sekine Chiyoko; Koyanagi Akemi; Koyama Noriko; Ogata Hideko; Chiba Shigeru; Hirose Sachiko; Okumura Ko; Yagita Hideo
Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice.
International immunology 2008;20(6):763-73.
2008: Kijima Mika; Yamaguchi Takeshi; Ishifune Chieko; Maekawa Yoichi; Koyanagi Akemi; Yagita Hideo; Chiba Shigeru; Kishihara Kenji; Shimada Mitsuo; Yasutomo Koji
Dendritic cell-mediated NK cell activation is controlled by Jagged2-Notch interaction.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(19):7010-5.
2008: Shanker Anil; Brooks Alan David; Tristan Carlos Alberto; Wine John William; Elliott Peter John; Yagita Hideo; Takeda Kazuyoshi; Smyth Mark John; Murphy William Joseph; Sayers Thomas Joseph
Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody.
Journal of the National Cancer Institute 2008;100(9):649-62.
2008: Smyth Mark J; Teng Michele W L; Sharkey Janelle; Westwood Jennifer A; Haynes Nicole M; Yagita Hideo; Takeda Kazuyoshi; Sivakumar Pallavur V; Kershaw Michael H
Interleukin 21 enhances antibody-mediated tumor rejection.
Cancer research 2008;68(8):3019-25.
2008: Edgtton Kristy L; Kausman Joshua Y; Li Ming; O'Sullivan Kim; Lo Cecilia; Hutchinson Paul; Yagita Hideo; Holdsworth Stephen R; Kitching A Richard
Intrarenal antigens activate CD4+ cells via co-stimulatory signals from dendritic cells.
Journal of the American Society of Nephrology : JASN 2008;19(3):515-26.
2008: Couzinet Arnaud; Tamura Kaoru; Chen Hui-Min; Nishimura Keishiro; Wang Zhichao; Morishita Yasuyuki; Takeda Kazuyoshi; Yagita Hideo; Yanai Hideyuki; Taniguchi Tadatsugu; Tamura Tomohiko
A cell-type-specific requirement for IFN regulatory factor 5 (IRF5) in Fas-induced apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2556-61.
2008: Yang Jun; Popoola Joyce; Khandwala Shakila; Vadivel Nidyanandh; Vanguri Vijay; Yuan Xueli; Dada Shirine; Guleria Indira; Tian Chaorui; Ansari M Javeed; Shin Tahiro; Yagita Hideo; Azuma Miyuki; Sayegh Mohamed H; Chandraker Anil
Critical role of donor tissue expression of programmed death ligand-1 in regulating cardiac allograft rejection and vasculopathy.
Circulation 2008;117(5):660-9.
2008: Ueno Takuya; Habicht Antje; Clarkson Michael R; Albin Monica J; Yamaura Kazuhiro; Boenisch Olaf; Popoola Joyce; Wang Ying; Yagita Hideo; Akiba Hisaya; Ansari M Javeed; Yang Jaeseok; Turka Laurence A; Rothstein David M; Padera Robert F; Najafian Nader; Sayegh Mohamed H
The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model.
The Journal of clinical investigation 2008;118(2):742-51.
2008: Matsumoto Koichiro; Fukuyama Satoru; Eguchi-Tsuda Miyuki; Nakano Takako; Matsumoto Takafumi; Matsumura Mikiko; Moriwaki Atsushi; Kan-o Keiko; Wada Yoshihiro; Yagita Hideo; Shin Tahiro; Pardoll Drew M; Patcharee Rirprajak; Azuma Miyuki; Nakanishi Yoichi; Inoue Hiromasa
B7-DC induced by IL-13 works as a feedback regulator in the effector phase of allergic asthma.
Biochemical and biophysical research communications 2008;365(1):170-5.
2008: Ito Y; Kanai T; Totsuka T; Okamoto R; Tsuchiya K; Nemoto Y; Yoshioka A; Tomita T; Nagaishi T; Sakamoto N; Sakanishi T; Okumura K; Yagita H; Watanabe M
Blockade of NKG2D signaling prevents the development of murine CD4+ T cell-mediated colitis.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(1):G199-207.
2008: Nakajima A; Kojima Y; Nakayama M; Yagita H; Okumura K; Nakano H
Downregulation of c-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells.
Oncogene 2008;27(1):76-84.
2008: Mohamood Abdiaziz S; Bargatze Dylan; Xiao Zuoxiang; Jie Chunfa; Yagita Hideo; Ruben Dawn; Watson Julie; Chakravarti Shukti; Schneck Jonathan P; Hamad Abdel Rahim A
Fas-mediated apoptosis regulates the composition of peripheral alphabeta T cell repertoire by constitutively purging out double negative T cells.
PloS one 2008;3(10):e3465.
2008: Fukushima Atsuki; Sumi Tamaki; Fukuda Ken; Kumagai Naoki; Nishida Teruo; Okumura Ko; Akiba Hisaya; Yagita Hideo; Ueno Hisayuki
Roles of galectin-9 in the development of experimental allergic conjunctivitis in mice.
International archives of allergy and immunology 2008;146(1):36-43.
2007: Persson Emma K; Agnarson Abela Mpobela; Lambert Henrik; Hitziger Niclas; Yagita Hideo; Chambers Benedict J; Barragan Antonio; Grandien Alf
Death receptor ligation or exposure to perforin trigger rapid egress of the intracellular parasite Toxoplasma gondii.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(12):8357-65.
2007: Hattori Takaaki; Usui Yoshihiko; Okunuki Yoko; Sonoda Yasushi; Usui Masahiko; Takada Eiko; Mizuguchi Junichiro; Yagita Hideo; Okumura Ko; Akiba Hisaya; Takeuchi Masaru
Blockade of the OX40 ligand prolongs corneal allograft survival.
European journal of immunology 2007;37(12):3597-604.
2007: Schumacher Anne; Wafula Paul O; Bertoja Annarosa Zambon; Sollwedel André; Thuere Catharina; Wollenberg Ivonne; Yagita Hideo; Volk Hans-Dieter; Zenclussen Ana Claudia
Mechanisms of action of regulatory T cells specific for paternal antigens during pregnancy.
Obstetrics and gynecology 2007;110(5):1137-45.
2007: Elyaman Wassim; Bradshaw Elizabeth M; Wang Yue; Oukka Mohamed; Kivisäkk Pia; Chiba Shigeru; Yagita Hideo; Khoury Samia J
JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):5990-8.
2007: Weckmann Markus; Collison Adam; Simpson Jodie L; Kopp Matthias V; Wark Peter A B; Smyth Mark J; Yagita Hideo; Matthaei Klaus I; Hansbro Nicole; Whitehead Bruce; Gibson Peter G; Foster Paul S; Mattes Joerg
Critical link between TRAIL and CCL20 for the activation of TH2 cells and the expression of allergic airway disease.
Nature medicine 2007;13(11):1308-15.
2007: Habicht Antje; Dada Shirine; Jurewicz Mollie; Fife Brian T; Yagita Hideo; Azuma Miyuki; Sayegh Mohamed H; Guleria Indira
A link between PDL1 and T regulatory cells in fetomaternal tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5211-9.
2007: Tanaka Katsunori; Albin Monica J; Yuan Xueli; Yamaura Kazuhiro; Habicht Antje; Murayama Takaya; Grimm Martin; Waaga Ana Maria; Ueno Takuya; Padera Robert F; Yagita Hideo; Azuma Miyuki; Shin Tahiro; Blazar Bruce R; Rothstein David M; Sayegh Mohamed H; Najafian Nader
PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5204-10.
2007: Fukushima Atsuki; Sumi Tamaki; Fukuda Ken; Kumagai Naoki; Nishida Teruo; Yamazaki Tomohide; Akiba Hisaya; Okumura Ko; Yagita Hideo; Ueno Hisayuki
B7-H3 regulates the development of experimental allergic conjunctivitis in mice.
Immunology letters 2007;113(1):52-7.
2007: Guleria Indira; Gubbels Bupp Melanie; Dada Shirine; Fife Brian; Tang Qizhi; Ansari Mohammed Javeed; Trikudanathan Subbulaxmi; Vadivel Nidyanandh; Fiorina Paolo; Yagita Hideo; Azuma Miyuki; Atkinson Mark; Bluestone Jeffrey A; Sayegh Mohamed H
Mechanisms of PDL1-mediated regulation of autoimmune diabetes.
Clinical immunology (Orlando, Fla.) 2007;125(1):16-25.
2007: Sharma Madhav D; Baban Babak; Chandler Phillip; Hou De-Yan; Singh Nagendra; Yagita Hideo; Azuma Miyuki; Blazar Bruce R; Mellor Andrew L; Munn David H
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase.
The Journal of clinical investigation 2007;117(9):2570-82.
2007: Teng Michele W L; Westwood Jennifer A; Darcy Phillip K; Sharkey Janelle; Tsuji Moriya; Franck Richard W; Porcelli Steven A; Besra Gurdyal S; Takeda Kazuyoshi; Yagita Hideo; Kershaw Michael H; Smyth Mark J
Combined natural killer T-cell based immunotherapy eradicates established tumors in mice.
Cancer research 2007;67(15):7495-504.
2007: Habicht A; Najafian N; Yagita H; Sayegh M H; Clarkson M R
New insights in CD28-independent allograft rejection.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(8):1917-26.
2007: Voskoboinik Ilia; Sutton Vivien R; Ciccone Annette; House Colin M; Chia Jenny; Darcy Phillip K; Yagita Hideo; Trapani Joseph A
Perforin activity and immune homeostasis: the common A91V polymorphism in perforin results in both presynaptic and postsynaptic defects in function.
Blood 2007;110(4):1184-90.
2007: Izawa Atsushi; Yamaura Kazuhiro; Albin Monica J; Jurewicz Mollie; Tanaka Katsunori; Clarkson Michael R; Ueno Takuya; Habicht Antje; Freeman Gordon J; Yagita Hideo; Abdi Reza; Pearson Todd; Greiner Dale L; Sayegh Mohamed H; Najafian Nader
A novel alloantigen-specific CD8+PD1+ regulatory T cell induced by ICOS-B7h blockade in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):786-96.
2007: Xiao Sheng; Najafian Nader; Reddy Jay; Albin Monica; Zhu Chen; Jensen Eric; Imitola Jaime; Korn Thomas; Anderson Ana C; Zhang Zheng; Gutierrez Cristina; Moll Thomas; Sobel Raymond A; Umetsu Dale T; Yagita Hideo; Akiba Hisaya; Strom Terry; Sayegh Mohamed H; DeKruyff Rosemarie H; Khoury Samia J; Kuchroo Vijay K
Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function.
The Journal of experimental medicine 2007;204(7):1691-702.
2007: Mohamood Abdiaziz S; Guler Mehmet L; Xiao Zuoxiang; Zheng Dongfeng; Hess Allan; Wang Yi; Yagita Hideo; Schneck Jonathan P; Hamad Abdel Rahim A
Protection from autoimmune diabetes and T-cell lymphoproliferation induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically.
The American journal of pathology 2007;171(1):97-106.
2007: Marzo Amanda L; Yagita Hideo; Lefrançois Leo
Cutting edge: migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(1):36-40.
2007: Seko Yoshinori; Yagita Hideo; Okumura Ko; Azuma Miyuki; Nagai Ryozo
Roles of programmed death-1 (PD-1)/PD-1 ligands pathway in the development of murine acute myocarditis caused by coxsackievirus B3.
Cardiovascular research 2007;75(1):158-67.
2007: Kim Juyang; Kim Hye J; Park Keunhee; Kim Jiyoung; Choi Hye-Jeong; Yagita Hideo; Nam Seok H; Cho Hong R; Kwon Byungsuk
Costimulatory molecule-targeted immunotherapy of cutaneous graft-versus-host disease.
Blood 2007;110(2):776-82.
2007: Fukushima Atsuki; Sumi Tamaki; Fukuda Ken; Kumagai Naoki; Nishida Teruo; Okumura Ko; Akiba Hisaya; Yagita Hideo; Ueno Hisayuki
T-cell Ig and mucin domain-containing protein (Tim)-2 regulates murine allergic conjunctivitis during the effector phase.
Immunology letters 2007;110(2):133-8.
2007: Takeda K; Stagg J; Yagita H; Okumura K; Smyth M J
Targeting death-inducing receptors in cancer therapy.
Oncogene 2007;26(25):3745-57.
2007: Soares Helena; Waechter HaeNa; Glaichenhaus Nicholas; Mougneau Evelyne; Yagita Hideo; Mizenina Olga; Dudziak Diana; Nussenzweig Michel C; Steinman Ralph M
A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo.
The Journal of experimental medicine 2007;204(5):1095-106.
2007: Fuse Shinichiro; Bellfy Sarah; Yagita Hideo; Usherwood Edward J
CD8+ T cell dysfunction and increase in murine gammaherpesvirus latent viral burden in the absence of 4-1BB ligand.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(8):5227-36.
2007: Nomi Takeo; Sho Masayuki; Akahori Takahiro; Hamada Kaoru; Kubo Atsushi; Kanehiro Hiromichi; Nakamura Shinji; Enomoto Koji; Yagita Hideo; Azuma Miyuki; Nakajima Yoshiyuki
Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(7):2151-7.
2007: Guillermo Landi V Costilla; Silva Elisabeth M; Ribeiro-Gomes Flávia L; De Meis Juliana; Pereira Wânia F; Yagita Hideo; DosReis George A; Lopes Marcela F
The Fas death pathway controls coordinated expansions of type 1 CD8 and type 2 CD4 T cells in Trypanosoma cruzi infection.
Journal of leukocyte biology 2007;81(4):942-51.
2007: Schildknecht Anita; Miescher Iris; Yagita Hideo; van den Broek Maries
Priming of CD8+ T cell responses by pathogens typically depends on CD70-mediated interactions with dendritic cells.
European journal of immunology 2007;37(3):716-28.
2007: Lepisto Andrew J; Xu Min; Yagita Hideo; Weinberg Andrew D; Hendricks Robert L
Expression and function of the OX40/OX40L costimulatory pair during herpes stromal keratitis.
Journal of leukocyte biology 2007;81(3):766-74.
2007: Piao Jiang-Hu; Yoshida Hisahiro; Yeh Wen-Chen; Doi Takahiro; Xue Xin; Yagita Hideo; Okumura Ko; Nakano Hiroyasu
TNF receptor-associated factor 2-dependent canonical pathway is crucial for the development of Peyer's patches.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2272-7.
2007: Sanchez Phillip J; McWilliams Jennifer A; Haluszczak Catherine; Yagita Hideo; Kedl Ross M
Combined TLR/CD40 stimulation mediates potent cellular immunity by regulating dendritic cell expression of CD70 in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1564-72.
2007: Fukushima Atsuki; Sumi Tamaki; Fukuda Ken; Kumagai Naoki; Nishida Teruo; Akiba Hisaya; Okumura Ko; Yagita Hideo; Ueno Hisayuki
Antibodies to T-cell Ig and mucin domain-containing proteins (Tim)-1 and -3 suppress the induction and progression of murine allergic conjunctivitis.
Biochemical and biophysical research communications 2007;353(1):211-6.
2007: Laouar Amale; Manocha Monika; Wan Meimei; Yagita Hideo; van Lier Rene A W; Manjunath N
Cutting Edge: Distinct NK receptor profiles are imprinted on CD8 T cells in the mucosa and periphery during the same antigen challenge: role of tissue-specific factors.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(2):652-6.
2007: Sumi Tamaki; Fukushima Atsuki; Fukuda Ken; Kumagai Naoki; Nishida Teruo; Yagita Hideo; Ueno Hisayuki
Differential contributions of B7-1 and B7-2 to the development of murine experimental allergic conjunctivitis.
Immunology letters 2007;108(1):62-7.
2007: van Wanrooij Eva J A; van Puijvelde Gijs H M; de Vos Paula; Yagita Hideo; van Berkel Theo J C; Kuiper Johan
Interruption of the Tnfrsf4/Tnfsf4 (OX40/OX40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(1):204-10.
2007: Salvato Maria S; Yin C Cameron; Yagita Hideo; Maeda Toshihiro; Okumura Ko; Tikhonov Ilia; Pauza C David
Attenuated disease in SIV-infected macaques treated with a monoclonal antibody against FasL.
Clinical & developmental immunology 2007;2007():93462.
2006: Martin-Orozco Natalia; Wang Yi-Hong; Yagita Hideo; Dong Chen
Cutting Edge: Programmed death (PD) ligand-1/PD-1 interaction is required for CD8+ T cell tolerance to tissue antigens.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(12):8291-5.
2006: Girgenrath Mahasweta; Weng Shawn; Kostek Christine A; Browning Beth; Wang Monica; Brown Sharron A N; Winkles Jeffrey A; Michaelson Jennifer S; Allaire Norm; Schneider Pascal; Scott Martin L; Hsu Yen-ming; Yagita Hideo; Flavell Richard A; Miller Jeffrey Boone; Burkly Linda C; Zheng Timothy S
TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration.
The EMBO journal 2006;25(24):5826-39.
2006: Inukai T; Zhang X; Goto M; Hirose K; Uno K; Akahane K; Nemoto A; Goi K; Sato H; Takahashi K; Honna H; Kagami K; Nakamoto K; Yagita H; Okumura K; Koyama-Okazaki T; Nakazawa S; Sugita K
Resistance of infant leukemia with MLL rearrangement to tumor necrosis factor-related apoptosis-inducing ligand: a possible mechanism for poor sensitivity to antitumor immunity.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(12):2119-29.
2006: Fukushima A; Sumi T; Fukuda K; Kumagai N; Nishida T; Yagita H; Ueno H
Interleukin 10 and transforming growth factor beta contribute to the development of experimentally induced allergic conjunctivitis in mice during the effector phase.
The British journal of ophthalmology 2006;90(12):1535-41.
2006: Fife Brian T; Guleria Indira; Gubbels Bupp Melanie; Eagar Todd N; Tang Qizhi; Bour-Jordan Helene; Yagita Hideo; Azuma Miyuki; Sayegh Mohamed H; Bluestone Jeffrey A
Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.
The Journal of experimental medicine 2006;203(12):2737-47.
2006: Nakajima Akihito; Komazawa-Sakon Sachiko; Takekawa Mutsuhiro; Sasazuki Tomonari; Yeh Wen-Chen; Yagita Hideo; Okumura Ko; Nakano Hiroyasu
An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway.
The EMBO journal 2006;25(23):5549-59.
2006: Nakashima Hiroyuki; Inui Takuo; Habu Yoshiko; Kinoshita Manabu; Nagao Shigeaki; Kawaguchi Atsushi; Miura Soichiro; Shinomiya Nariyoshi; Yagita Hideo; Seki Shuhji
Activation of mouse natural killer T cells accelerates liver regeneration after partial hepatectomy.
Gastroenterology 2006;131(5):1573-83.
2006: Kamata Koichi; Kamijo Seiji; Nakajima Atsuo; Koyanagi Akemi; Kurosawa Hisashi; Yagita Hideo; Okumura Ko
Involvement of TNF-like weak inducer of apoptosis in the pathogenesis of collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):6433-9.
2006: Hori Junko; Wang Mingcong; Miyashita Megumi; Tanemoto Keiko; Takahashi Hiroshi; Takemori Toshitada; Okumura Ko; Yagita Hideo; Azuma Miyuki
B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):5928-35.
2006: Usui Yoshihiko; Akiba Hisaya; Takeuchi Masaru; Kezuka Takeshi; Takeuchi Aya; Hattori Takaaki; Okunuki Yoko; Yamazaki Tomohide; Yagita Hideo; Usui Masahiko; Okumura Ko
The role of the ICOS/B7RP-1 T cell costimulatory pathway in murine experimental autoimmune uveoretinitis.
European journal of immunology 2006;36(11):3071-81.
2006: Oikawa Tsunekazu; Kamimura Yosuke; Akiba Hisaya; Yagita Hideo; Okumura Ko; Takahashi Hiroki; Zeniya Mikio; Tajiri Hisao; Azuma Miyuki
Preferential involvement of Tim-3 in the regulation of hepatic CD8+ T cells in murine acute graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4281-7.
2006: Baran Katherine; Ciccone Annette; Peters Christoph; Yagita Hideo; Bird Phillip I; Villadangos Jose A; Trapani Joseph A
Cytotoxic T lymphocytes from cathepsin B-deficient mice survive normally in vitro and in vivo after encountering and killing target cells.
The Journal of biological chemistry 2006;281(41):30485-91.
2006: Matter Matthias; Odermatt Bernhard; Yagita Hideo; Nuoffer Jean-Marc; Ochsenbein Adrian F
Elimination of chronic viral infection by blocking CD27 signaling.
The Journal of experimental medicine 2006;203(9):2145-55.
2006: Kamijo Seiji; Nakajima Atsuo; Ikeda Kaori; Aoki Kazuhiro; Ohya Keiichi; Akiba Hisaya; Yagita Hideo; Okumura Ko
Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody.
Biochemical and biophysical research communications 2006;347(1):124-32.
2006: Fukushima A; Yamaguchi T; Azuma M; Yagita H; Ueno H
Involvement of programmed death-ligand 2 (PD-L2) in the development of experimental allergic conjunctivitis in mice.
The British journal of ophthalmology 2006;90(8):1040-5.
2006: Kanai Takanori; Uraushihara Koji; Totsuka Teruji; Nemoto Yasuhiro; Fujii Rei; Kawamura Takahiro; Makita Shin; Sawada Daisuke; Yagita Hideo; Okumura Ko; Watanabe Mamoru
Ameliorating effect of saporin-conjugated anti-CD11b monoclonal antibody in a murine T-cell-mediated chronic colitis.
Journal of gastroenterology and hepatology 2006;21(7):1136-42.
2006: Uno Tomoyasu; Takeda Kazuyoshi; Kojima Yuko; Yoshizawa Hirohisa; Akiba Hisaya; Mittler Robert S; Gejyo Fumitake; Okumura Ko; Yagita Hideo; Smyth Mark J
Eradication of established tumors in mice by a combination antibody-based therapy.
Nature medicine 2006;12(6):693-8.
2006: Smyth Mark J; Hayakawa Yoshihiro; Cretney Erika; Zerafa Nadeen; Sivakumar Pallavur; Yagita Hideo; Takeda Kazuyoshi
IL-21 enhances tumor-specific CTL induction by anti-DR5 antibody therapy.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(10):6347-55.
2006: Beaudette-Zlatanova B C; Whalen B; Zipris D; Yagita H; Rozing J; Groen H; Benjamin C D; Hunig T; Drexhage H A; Ansari M J; Leif J; Mordes J P; Greiner D L; Sayegh M H; Rossini A A
Costimulation and autoimmune diabetes in BB rats.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2006;6(5 Pt 1):894-902.
2006: Lee Kyung-Mi; Forman John P; McNerney Megan E; Stepp Susan; Kuppireddi Sumalatha; Guzior Dustin; Latchman Yvette E; Sayegh Mohamed H; Yagita Hideo; Park Chul-Kyu; Oh Seog Bae; Wülfing Christoph; Schatzle John; Mathew Porunelloor A; Sharpe Arlene H; Kumar Vinay
Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions.
Blood 2006;107(8):3181-8.
2006: Zhu Bing; Guleria Indira; Khosroshahi Arezou; Chitnis Tanuja; Imitola Jaime; Azuma Miyuki; Yagita Hideo; Sayegh Mohamed H; Khoury Samia J
Differential role of programmed death-ligand 1 [corrected] and programmed death-ligand 2 [corrected] in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3480-9.
2006: MacPhee Iain A M; Yagita Hideo; Oliveira David B G
Blockade of OX40-ligand after initial triggering of the T helper 2 response inhibits mercuric chloride-induced autoimmunity.
Immunology 2006;117(3):402-8.
2006: Abadía-Molina Ana C; Ji Honbing; Faubion William A; Julien Aimée; Latchman Yvette; Yagita Hideo; Sharpe Arlene; Bhan Atul K; Terhorst Cox
CD48 controls T-cell and antigen-presenting cell functions in experimental colitis.
Gastroenterology 2006;130(2):424-34.
2006: Chinen Takatoshi; Kobayashi Takashi; Ogata Hisanobu; Takaesu Giichi; Takaki Hiromi; Hashimoto Masayuki; Yagita Hideo; Nawata Hajime; Yoshimura Akihiko
Suppressor of cytokine signaling-1 regulates inflammatory bowel disease in which both IFNgamma and IL-4 are involved.
Gastroenterology 2006;130(2):373-88.
2006: Taieb Julien; Chaput Nathalie; Ménard Cédric; Apetoh Lionel; Ullrich Evelyn; Bonmort Mathieu; Péquignot Marie; Casares Noelia; Terme Magali; Flament Caroline; Opolon Paule; Lecluse Yann; Métivier Didier; Tomasello Elena; Vivier Eric; Ghiringhelli François; Martin François; Klatzmann David; Poynard Thierry; Tursz Thomas; Raposo Graça; Yagita Hideo; Ryffel Bernard; Kroemer Guido; Zitvogel Laurence
A novel dendritic cell subset involved in tumor immunosurveillance.
Nature medicine 2006;12(2):214-9.
2006: Fukushima Atsuki; Yamaguchi Tomoko; Ishida Waka; Fukata Kazuyo; Yagita Hideo; Ueno Hisayuki
Roles of OX40 in the development of murine experimental allergic conjunctivitis: exacerbation and attenuation by stimulation and blocking of OX40.
Investigative ophthalmology & visual science 2006;47(2):657-63.
2006: Vu Minh Diem; Clarkson Michael R; Yagita Hideo; Turka Laurence A; Sayegh Mohamed H; Li Xian Chang
Critical, but conditional, role of OX40 in memory T cell-mediated rejection.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1394-401.
2006: Cretney Erika; Shanker Anil; Yagita Hideo; Smyth Mark J; Sayers Thomas J
TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer.
Immunology and cell biology 2006;84(1):87-98.
2006: Ding Hanlu; Wu Xiongfei; Wu Jun; Yagita Hideo; He Yani; Zhang Jianguo; Ren Jiangwen; Gao Wenda
Delivering PD-1 inhibitory signal concomitant with blocking ICOS co-stimulation suppresses lupus-like syndrome in autoimmune BXSB mice.
Clinical immunology (Orlando, Fla.) 2006;118(2-3):258-67.
2006: Seo Su-Kil; Seo Hyoun-Mi; Jeong Hye-Young; Choi Il-Whan; Park Yeong-Min; Yagita Hideo; Chen Lipieng; Choi In-Hak
Co-inhibitory role of T-cell-associated B7-H1 and B7-DC in the T-cell immune response.
Immunology letters 2006;102(2):222-8.
2006: Tafuku Senji; Matsuda Takehiro; Kawakami Hirochika; Tomita Mariko; Yagita Hideo; Mori Naoki
Potential mechanism of resistance to TRAIL-induced apoptosis in Burkitt's lymphoma.
European journal of haematology 2006;76(1):64-74.
2006: Cheuk Adam T C; Chan Lucas; Czepulkowski Barbara; Berger Stuart A; Yagita Hideo; Okumura Ko; Farzaneh Farzin; Mufti Ghulam J; Guinn Barbara-ann
Development of a whole cell vaccine for acute myeloid leukaemia.
Cancer immunology, immunotherapy : CII 2006;55(1):68-75.
2006: Ando Takashi; Ichikawa Jiro; Wako Masanori; Hatsushika Kyosuke; Watanabe Yoshiyuki; Sakuma Michitomo; Tasaka Kachio; Ogawa Hideoki; Hamada Yoshiki; Yagita Hideo; Nakao Atsuhito
TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells.
Arthritis research & therapy 2006;8(5):R146.
2005: Baumann Petra; Cremers Natascha; Kroese Frans; Orend Gertraud; Chiquet-Ehrismann Ruth; Uede Toshi; Yagita Hideo; Sleeman Jonathan P
CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis.
Cancer research 2005;65(23):10783-93.
2005: Fukushima Atsuki; Yamaguchi Tomoko; Ishida Waka; Fukata Kazuyo; Yagita Hideo; Ueno Hisayuki
The interaction between ICOS and B7RP-1 is not required for the development of experimental murine allergic conjunctivitis.
Biochemical and biophysical research communications 2005;338(4):1726-31.
2005: Ruiz-Perez Begonia; Chung Doo R; Sharpe Arlene H; Yagita Hideo; Kalka-Moll Wiltrud M; Sayegh Mohamed H; Kasper Dennis L; Tzianabos Arthur O
Modulation of surgical fibrosis by microbial zwitterionic polysaccharides.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(46):16753-8.
2005: Miyahira Yasushi; Takashima Yasuhiro; Kobayashi Seiki; Matsumoto Yasunobu; Takeuchi Tsutomu; Ohyanagi-Hara Mutsuko; Yoshida Ayako; Ohwada Akihiko; Akiba Hisaya; Yagita Hideo; Okumura Ko; Ogawa Hideoki
Immune responses against a single CD8+-T-cell epitope induced by virus vector vaccination can successfully control Trypanosoma cruzi infection.
Infection and immunity 2005;73(11):7356-65.
2005: Matter Matthias; Mumprecht Sabine; Pinschewer Daniel D; Pavelic Viktor; Yagita Hideo; Krautwald Stefan; Borst Jannie; Ochsenbein Adrian F
Virus-induced polyclonal B cell activation improves protective CTL memory via retained CD27 expression on memory CTL.
European journal of immunology 2005;35(11):3229-39.
2005: Herbeuval Jean-Philippe; Grivel Jean-Charles; Boasso Adriano; Hardy Andrew W; Chougnet Claire; Dolan Matthew J; Yagita Hideo; Lifson Jeffrey D; Shearer Gene M
CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis.
Blood 2005;106(10):3524-31.
2005: Fukushima Atsuki; Yamaguchi Tomoko; Ishida Waka; Fukata Kazuyo; Mittler Robert S; Yagita Hideo; Ueno Hisayuki
Engagement of 4-1BB inhibits the development of experimental allergic conjunctivitis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(8):4897-903.
2005: Cretney Erika; McQualter Jonathan L; Kayagaki Nobuhiko; Yagita Hideo; Bernard Claude C A; Grewal Iqbal S; Ashkenazi Avi; Smyth Mark J
TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L suppresses experimental autoimmune encephalomyelitis in mice.
Immunology and cell biology 2005;83(5):511-9.
2005: Xue Xin; Piao Jiang-Hu; Nakajima Akihito; Sakon-Komazawa Sachiko; Kojima Yuko; Mori Kazutoshi; Yagita Hideo; Okumura Ko; Harding Heather; Nakano Hiroyasu
Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha.
The Journal of biological chemistry 2005;280(40):33917-25.
2005: Akiba Hisaya; Takeda Kazuyoshi; Kojima Yuko; Usui Yoshihiko; Harada Norihiro; Yamazaki Tomohide; Ma Juan; Tezuka Katsunari; Yagita Hideo; Okumura Ko
The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2340-8.
2005: Zimmerman Zachary; Shatry Alwi; Deyev Vadim; Podack Eckhard; Mammolenti Michele; Blazar Bruce R; Yagita Hideo; Levy Robert B
Effector cells derived from host CD8 memory T cells mediate rapid resistance against minor histocompatibility antigen-mismatched allogeneic marrow grafts without participation of perforin, Fas ligand, and the simultaneous inhibition of 3 tumor necrosis factor family effector pathways.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(8):576-86.
2005: Yamazaki Tomohide; Akiba Hisaya; Koyanagi Akemi; Azuma Miyuki; Yagita Hideo; Okumura Ko
Blockade of B7-H1 on macrophages suppresses CD4+ T cell proliferation by augmenting IFN-gamma-induced nitric oxide production.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1586-92.
2005: Kawamura Hiroki; Yagita Hideo; Nisizawa Tetsuro; Izumi Nakako; Miyaji Chikako; Vance Russell E; Raulet David H; Okumura Ko; Abo Toru
Amelioration of acute graft-versus-host disease by NKG2A engagement on donor T cells.
European journal of immunology 2005;35(8):2358-66.
2005: Guleria Indira; Khosroshahi Arezou; Ansari Mohammed Javeed; Habicht Antje; Azuma Miyuki; Yagita Hideo; Noelle Randolph J; Coyle Anthony; Mellor Andrew L; Khoury Samia J; Sayegh Mohamed H
A critical role for the programmed death ligand 1 in fetomaternal tolerance.
The Journal of experimental medicine 2005;202(2):231-7.
2005: Hara Keiichi; Okamoto Mayumi; Aki Toshihiko; Yagita Hideo; Tanaka Hirotoshi; Mizukami Yoichi; Nakamura Hiroshi; Tomoda Akio; Hamasaki Naotaka; Kang Dongchon
Synergistic enhancement of TRAIL- and tumor necrosis factor alpha-induced cell death by a phenoxazine derivative.
Molecular cancer therapeutics 2005;4(7):1121-7.
2005: Bashuda Hisashi; Kimikawa Masaaki; Seino Kenichiro; Kato Yojiro; Ono Fumiko; Shimizu Akira; Yagita Hideo; Teraoka Satoshi; Okumura Ko
Renal allograft rejection is prevented by adoptive transfer of anergic T cells in nonhuman primates.
The Journal of clinical investigation 2005;115(7):1896-902.
2005: Ota Tsuyoshi; Takeda Kazuyoshi; Akiba Hisaya; Hayakawa Yoshihiro; Ogasawara Kouetsu; Ikarashi Yoshinori; Miyake Sachiko; Wakasugi Hiro; Yamamura Takashi; Kronenberg Mitchell; Raulet David H; Kinoshita Katsuyuki; Yagita Hideo; Smyth Mark J; Okumura Ko
IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2.
Blood 2005;106(1):184-92.
2005: Smyth Mark J; Wallace Morgan E; Nutt Stephen L; Yagita Hideo; Godfrey Dale I; Hayakawa Yoshihiro
Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer.
The Journal of experimental medicine 2005;201(12):1973-85.
2005: Tani-ichi Shizue; Maruyama Koji; Kondo Nami; Nagafuku Masakazu; Kabayama Kazuya; Inokuchi Jin-ichi; Shimada Yukiko; Ohno-Iwashita Yoshiko; Yagita Hideo; Kawano Sunao; Kosugi Atsushi
Structure and function of lipid rafts in human activated T cells.
International immunology 2005;17(6):749-58.
2005: Ito Toshiro; Ueno Takuya; Clarkson Michael R; Yuan Xueli; Jurewicz Mollie M; Yagita Hideo; Azuma Miyuki; Sharpe Arlene H; Auchincloss Hugh; Sayegh Mohamed H; Najafian Nader
Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):6648-56.
2005: Totsuka Teruji; Kanai Takanori; Makita Shin; Fujii Rei; Nemoto Yasuhiro; Oshima Shigeru; Okamoto Ryuichi; Koyanagi Akemi; Akiba Hisaya; Okumura Ko; Yagita Hideo; Watanabe Mamoru
Regulation of murine chronic colitis by CD4+CD25- programmed death-1+ T cells.
European journal of immunology 2005;35(6):1773-85.
2005: Tanaka Toshitaka; Ebata Tomohiko; Tajima Atsushi; Kinoshita Katsuyuki; Okumura Ko; Yagita Hideo
Beta2-microglobulin required for cell surface expression of blastocyst MHC.
Biochemical and biophysical research communications 2005;332(1):311-7.
2005: Kaduka Yuki; Takeda Kazuyoshi; Nakayama Masafumi; Kinoshita Katsuyuki; Yagita Hideo; Okumura Ko
TWEAK mediates anti-tumor effect of tumor-infiltrating macrophage.
Biochemical and biophysical research communications 2005;331(2):384-90.
2005: Aramaki O; Inoue F; Takayama T; Shimazu M; Kitajima M; Ikeda Y; Okumura K; Yagita H; Shirasugi N; Niimi M
Various costimulatory pathways are essential for induction of regulatory cells by intratracheal delivery of alloantigen.
Transplantation proceedings 2005;37(4):1934-6.
2005: Kashizuka Hisanori; Sho Masayuki; Nomi Takeo; Ikeda Naoya; Kuzumoto Yukiyasu; Akashi Satoru; Tsurui Yoshikazu; Mizuno Takashi; Kanehiro Hiromichi; Yagita Hideo; Nakajima Yoshiyuki; Sayegh Mohamed H
Role of the ICOS-B7h costimulatory pathway in the pathophysiology of chronic allograft rejection.
Transplantation 2005;79(9):1045-50.
2005: Tsukahara Rintaro; Takeuchi Masaru; Akiba Hisaya; Kezuka Takeshi; Takeda Kazuyoshi; Usui Yoshihiko; Usui Masahiko; Yagita Hideo; Okumura Ko
Critical contribution of CD80 and CD86 to induction of anterior chamber-associated immune deviation.
International immunology 2005;17(5):523-30.
2005: Ohigashi Yuichiro; Sho Masayuki; Yamada Yukishige; Tsurui Yoshikazu; Hamada Kaoru; Ikeda Naoya; Mizuno Takashi; Yoriki Ryo; Kashizuka Hisanori; Yane Katsunari; Tsushima Fumihiko; Otsuki Noriko; Yagita Hideo; Azuma Miyuki; Nakajima Yoshiyuki
Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(8):2947-53.
2005: Shao Ruping; Lee Dung-Fang; Wen Yong; Ding Yi; Xia Weiya; Ping Bo; Yagita Hideo; Spohn Bill; Hung Mien-Chie
E1A sensitizes cancer cells to TRAIL-induced apoptosis through enhancement of caspase activation.
Molecular cancer research : MCR 2005;3(4):219-26.
2005: Matsuda Takehiro; Almasan Alex; Tomita Mariko; Tamaki Kazumi; Saito Mika; Tadano Masayuki; Yagita Hideo; Ohta Takao; Mori Naoki
Dengue virus-induced apoptosis in hepatic cells is partly mediated by Apo2 ligand/tumour necrosis factor-related apoptosis-inducing ligand.
The Journal of general virology 2005;86(Pt 4):1055-65.
2005: Sato Katsuaki; Nakaoka Takashi; Yamashita Naohide; Yagita Hideo; Kawasaki Hiroshi; Morimoto Chikao; Baba Masanori; Matsuyama Takami
TRAIL-transduced dendritic cells protect mice from acute graft-versus-host disease and leukemia relapse.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):4025-33.
2005: Aramaki Osamu; Inoue Fumihiko; Takayama Tadatoshi; Shimazu Motohide; Kitajima Masaki; Ikeda Yoshifumi; Okumura Ko; Yagita Hideo; Shirasugi Nozomu; Niimi Masanori
Interleukin-10 but not transforming growth factor-beta is essential for generation and suppressor function of regulatory cells induced by intratracheal delivery of alloantigen.
Transplantation 2005;79(5):568-76.
2005: Sandner Sigrid E; Clarkson Michael R; Salama Alan D; Sanchez-Fueyo Alberto; Domenig Christoph; Habicht Antje; Najafian Nader; Yagita Hideo; Azuma Miyuki; Turka Laurence A; Sayegh Mohamed H
Role of the programmed death-1 pathway in regulation of alloimmune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3408-15.
2005: Takeda Kazuyoshi; Cretney Erika; Hayakawa Yoshihiro; Ota Tsuyoshi; Akiba Hisaya; Ogasawara Kouetsu; Yagita Hideo; Kinoshita Katsuyuki; Okumura Ko; Smyth Mark J
TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver.
Blood 2005;105(5):2082-9.
2005: Yamada Akira; Salama Alan D; Sho Masayuki; Najafian Nader; Ito Toshiro; Forman John P; Kewalramani Reshma; Sandner Sigrid; Harada Hiroshi; Clarkson Michael R; Mandelbrot Didier A; Sharpe Arlene H; Oshima Hideo; Yagita Hideo; Chalasani Geetha; Lakkis Fadi G; Auchincloss Hugh; Sayegh Mohamed H
CD70 signaling is critical for CD28-independent CD8+ T cell-mediated alloimmune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1357-64.
2005: Matsuda Takehiro; Almasan Alex; Tomita Mariko; Uchihara Jun-nosuke; Masuda Masato; Ohshiro Kazuiku; Takasu Nobuyuki; Yagita Hideo; Ohta Takao; Mori Naoki
Resistance to Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis and constitutive expression of Apo2L/TRAIL in human T-cell leukemia virus type 1-infected T-cell lines.
Journal of virology 2005;79(3):1367-78.
2005: Kaneda Hiroshi; Takeda Kazuyoshi; Ota Tsuyoshi; Kaduka Yuki; Akiba Hisaya; Ikarashi Yoshinori; Wakasugi Hiro; Kronenberg Mitchell; Kinoshita Katsuyuki; Yagita Hideo; Okumura Ko
ICOS costimulates invariant NKT cell activation.
Biochemical and biophysical research communications 2005;327(1):201-7.
2005: Smyth Mark J; Cretney Erika; Kelly Janice M; Westwood Jennifer A; Street Shayna E A; Yagita Hideo; Takeda Kazuyoshi; van Dommelen Serani L H; Degli-Esposti Mariapia A; Hayakawa Yoshihiro
Activation of NK cell cytotoxicity.
Molecular immunology 2005;42(4):501-10.
2005: Sandner Sigrid E; Clarkson Michael R; Salama Alan D; Sanchez-Fueyo Alberto; Yagita Hideo; Turka Laurence A; Sayegh Mohamed H
Mechanisms of tolerance induced by donor-specific transfusion and ICOS-B7h blockade in a model of CD4+ T-cell-mediated allograft rejection.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(1):31-9.
2005: Bullock Timothy N J; Yagita Hideo
Induction of CD70 on dendritic cells through CD40 or TLR stimulation contributes to the development of CD8+ T cell responses in the absence of CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(2):710-7.
2004: Lundin Katrin U; Screpanti Valentina; Omholt Hilde; Hofgaard Peter O; Yagita Hideo; Grandien Alf; Bogen Bjarne
CD4+ T cells kill Id+ B-lymphoma cells: FasLigand-Fas interaction is dominant in vitro but is redundant in vivo.
Cancer immunology, immunotherapy : CII 2004;53(12):1135-45.
2004: Yamamoto Tameyoshi; Nagano Hiroaki; Sakon Masato; Wada Hisashi; Eguchi Hidetoshi; Kondo Motoi; Damdinsuren Bazarragchaa; Ota Hideo; Nakamura Masato; Wada Hiroshi; Marubashi Shigeru; Miyamoto Atsushi; Dono Keizo; Umeshita Koji; Nakamori Shoji; Yagita Hideo; Monden Morito
Partial contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/TRAIL receptor pathway to antitumor effects of interferon-alpha/5-fluorouracil against Hepatocellular Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(23):7884-95.
2004: Nishiyama Chiharu; Akizawa Yushiro; Nishiyama Makoto; Tokura Tomoko; Kawada Hiroshi; Mitsuishi Kouichi; Hasegawa Masanari; Ito Tomonobu; Nakano Nobuhiro; Okamoto Atsushi; Takagi Atsushi; Yagita Hideo; Okumura Ko; Ogawa Hideoki
Polymorphisms in the Fc epsilon RI beta promoter region affecting transcription activity: a possible promoter-dependent mechanism for association between Fc epsilon RI beta and atopy.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6458-64.
2004: Flórido Manuela; Borges Margarida; Yagita Hideo; Appelberg Rui
Contribution of CD30/CD153 but not of CD27/CD70, CD134/OX40L, or CD137/4-1BBL to the optimal induction of protective immunity to Mycobacterium avium.
Journal of leukocyte biology 2004;76(5):1039-46.
2004: Ozaki Akemi; Fukushima Atsuki; Ishida Waka; Zinchuk Olga; Fukata Kazuyo; Hayashi Yoshihiro; Enzan Hideaki; Takata Masaru; Yagita Hideo; Ueno Hisayuki
Analysis of Ag-presenting cells in the conjunctiva during the development of experimental immune-mediated blepharoconjunctivitis.
Current eye research 2004;29(4-5):277-86.
2004: Kasuga Chinatsu; Ebata Tomohiko; Kayagaki Nobuhiko; Yagita Hideo; Hishii Makoto; Arai Hajime; Sato Kiyoshi; Okumura Ko
Sensitization of human glioblastomas to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by NF-kappaB inhibitors.
Cancer science 2004;95(10):840-4.
2004: Yagita Hideo; Takeda Kazuyoshi; Hayakawa Yoshihiro; Smyth Mark J; Okumura Ko
TRAIL and its receptors as targets for cancer therapy.
Cancer science 2004;95(10):777-83.
2004: Diao Hongyan; Kon Shigeyuki; Iwabuchi Kazuya; Kimura Chiemi; Morimoto Junko; Ito Daisuke; Segawa Tatsuya; Maeda Masahiro; Hamuro Junji; Nakayama Toshinori; Taniguchi Masaru; Yagita Hideo; Van Kaer Luc; Onóe Kazunori; Denhardt David; Rittling Susan; Uede Toshimitsu
Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases.
Immunity 2004;21(4):539-50.
2004: Luo Jun-Li; Maeda Shin; Hsu Li-Chung; Yagita Hideo; Karin Michael
Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression.
Cancer cell 2004;6(3):297-305.
2004: Izawa Kiyoko; Tani Kenzaburo; Nakazaki Yukoh; Hibino Hitoshi; Sugiyama Hajime; Kawasaki Akemi; Sasaki Erika; Nishioka Chieko; Ishii Hajime; Soda Yasushi; Yagita Hideo; Tanioka Yoshikuni; Tojo Arinobu; Asano Shigetaka
Hematopoietic activity of common marmoset CD34 cells isolated by a novel monoclonal antibody MA24.
Experimental hematology 2004;32(9):843-51.
2004: Blazar Bruce R; Levy Robert B; Mak Tak W; Panoskaltsis-Mortari Angela; Muta Hiromi; Jones Monica; Roskos Melinda; Serody Jonathan S; Yagita Hideo; Podack Eckhard R; Taylor Patricia A
CD30/CD30 ligand (CD153) interaction regulates CD4+ T cell-mediated graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):2933-41.
2004: Cho H R; Kwon B; Yagita H; La S; Lee E A; Kim J-E; Akiba H; Kim J; Suh J-H; Vinay D S; Ju S-A; Kim B-S; Mittler R S; Okumura K; Kwon B S
Blockade of 4-1BB (CD137)/4-1BB ligand interactions increases allograft survival.
Transplant international : official journal of the European Society for Organ Transplantation 2004;17(7):351-61.
2004: Sasazuki Tomonari; Okazaki Tatsuma; Tada Kurisu; Sakon-Komazawa Sachiko; Katano Mitsuo; Tanaka Masao; Yagita Hideo; Okumura Ko; Tominaga Naoko; Hayashizaki Yoshihide; Okazaki Yasushi; Nakano Hiroyasu
Genome wide analysis of TNF-inducible genes reveals that antioxidant enzymes are induced by TNF and responsible for elimination of ROS.
Molecular immunology 2004;41(5):547-51.
2004: Suzui Masatoshi; Kawai Takeshi; Kimura Hiroko; Takeda Kazuyoshi; Yagita Hideo; Okumura Ko; Shek Pang N; Shephard Roy J
Natural killer cell lytic activity and CD56(dim) and CD56(bright) cell distributions during and after intensive training.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;96(6):2167-73.
2004: Hao Zhenyue; Hampel Brigitte; Yagita Hideo; Rajewsky Klaus
T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
The Journal of experimental medicine 2004;199(10):1355-65.
2004: Jin Long; Nakao Atsuhito; Nakayama Masafumi; Yamaguchi Noriko; Kojima Yuko; Nakano Nobuhiro; Tsuboi Ryoji; Okumura Ko; Yagita Hideo; Ogawa Hideoki
Induction of RANTES by TWEAK/Fn14 interaction in human keratinocytes.
The Journal of investigative dermatology 2004;122(5):1175-9.
2004: Xu Hongri; Okamoto Atsushi; Ichikawa Jiro; Ando Takashi; Tasaka Kachio; Masuyama Keisuke; Ogawa Hideoki; Yagita Hideo; Okumura Ko; Nakao Atsuhito
TWEAK/Fn14 interaction stimulates human bronchial epithelial cells to produce IL-8 and GM-CSF.
Biochemical and biophysical research communications 2004;318(2):422-7.
2004: Holsti Matthew A; Chitnis Tanuja; Panzo Ronald J; Bronson Roderick T; Yagita Hideo; Sayegh Mohamed H; Tzianabos Arthur O
Regulation of postsurgical fibrosis by the programmed death-1 inhibitory pathway.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(9):5774-81.
2004: Hasegawa Akihiro; Cheng Xin; Kajino Kiichi; Berezov Alan; Murata Kaoru; Nakayama Toshinori; Yagita Hideo; Murali Ramachandran; Greene Mark I
Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(17):6599-604.
2004: Kohyama Masako; Sugahara Daisuke; Sugiyama Shigeru; Yagita Hideo; Okumura Ko; Hozumi Nobumichi
Inducible costimulator-dependent IL-10 production by regulatory T cells specific for self-antigen.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(12):4192-7.
2004: Street Shayna E A; Hayakawa Yoshihiro; Zhan Yifan; Lew Andrew M; MacGregor Duncan; Jamieson Amanda M; Diefenbach Andreas; Yagita Hideo; Godfrey Dale I; Smyth Mark J
Innate immune surveillance of spontaneous B cell lymphomas by natural killer cells and gammadelta T cells.
The Journal of experimental medicine 2004;199(6):879-84.
2004: Lichtner Miriam; Marañón Concepción; Vidalain Pierre-Olivier; Azocar Olga; Hanau Daniel; Lebon Pierre; Burgard Marianne; Rouzioux Christine; Vullo Vincenzo; Yagita Hideo; Rabourdin-Combe Chantal; Servet Christine; Hosmalin Anne
HIV type 1-infected dendritic cells induce apoptotic death in infected and uninfected primary CD4 T lymphocytes.
AIDS research and human retroviruses 2004;20(2):175-82.
2004: Takeda Kazuyoshi; Yamaguchi Noriko; Akiba Hisaya; Kojima Yuko; Hayakawa Yoshihiro; Tanner Jane E; Sayers Thomas J; Seki Naoko; Okumura Ko; Yagita Hideo; Smyth Mark J
Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.
The Journal of experimental medicine 2004;199(4):437-48.
2004: Matsumoto Koichiro; Inoue Hiromasa; Nakano Takako; Tsuda Miyuki; Yoshiura Yuki; Fukuyama Satoru; Tsushima Fumihiko; Hoshino Tomoaki; Aizawa Hisamichi; Akiba Hisaya; Pardoll Drew; Hara Nobuyuki; Yagita Hideo; Azuma Miyuki; Nakanishi Yoichi
B7-DC regulates asthmatic response by an IFN-gamma-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2530-41.
2004: Demirci Gülçin; Amanullah Farhana; Kewalaramani Reshma; Yagita Hideo; Strom Terry B; Sayegh Mohamed H; Li Xian Chang
Critical role of OX40 in CD28 and CD154-independent rejection.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1691-8.
2004: Seko Yoshinori; Sugishita Kazuyuki; Sato Osamu; Takagi Atsuhiko; Tada Yusuke; Matsuo Hiroshi; Yagita Hideo; Okumura Ko; Nagai Ryozo
Expression of costimulatory molecules (4-1BBL and Fas) and major histocompatibility class I chain-related A (MICA) in aortic tissue with Takayasu's arteritis.
Journal of vascular research 2004;41(1):84-90.
2004: Aramaki Osamu; Shirasugi Nozomu; Takayama Tadatoshi; Shimazu Motohide; Kitajima Masaki; Ikeda Yoshifumi; Azuma Miyuki; Okumura Ko; Yagita Hideo; Niimi Masanori
Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen.
Transplantation 2004;77(1):6-12.
2004: Hayakawa Yoshihiro; Screpanti Valentina; Yagita Hideo; Grandien Alf; Ljunggren Hans-Gustaf; Smyth Mark J; Chambers Benedict J
NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):123-9.
2003: Miyahira Yasushi; Akiba Hisaya; Katae Masaharu; Kubota Kaori; Kobayashi Seiki; Takeuchi Tsutomu; García-Sastre Adolfo; Fukuchi Yoshinosuke; Okumura Ko; Yagita Hideo; Aoki Takashi
Cutting edge: a potent adjuvant effect of ligand to receptor activator of NF-kappa B gene for inducing antigen-specific CD8+ T cell response by DNA and viral vector vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6344-8.
2003: Ito Taisuke; Seo Naohiro; Yagita Hideo; Tsujimura Kunio; Takigawa Masahiro; Tokura Yoshiki
Alterations of immune functions in barrier disrupted skin by UVB irradiation.
Journal of dermatological science 2003;33(3):151-9.
2003: Matsui Yuichi; Saiura Akio; Sugawara Yasuhiko; Sata Masataka; Naruse Katsutoshi; Yagita Hideo; Kohro Takahide; Mataki Chikage; Izumi Akashi; Yamaguchi Takuhiro; Minami Takashi; Sakihama Toshiko; Ihara Sigeo; Aburatani Hiroyuki; Hamakubo Takao; Kodama Tatsuhiko; Makuuchi Masatoshi
Identification of gene expression profile in tolerizing murine cardiac allograft by costimulatory blockade.
Physiological genomics 2003;15(3):199-208.
2003: Miyahira Yasushi; Akiba Hisaya; Ogawa Shu-Hei; Ishi Tomohiro; Watanabe Shiho; Kobayashi Seiki; Takeuchi Tsutomu; Aoki Takashi; Tezuka Katsunari; Abe Ryo; Okumura Ko; Yagita Hideo; Watanabe Naohiro
Involvement of ICOS-B7RP-1 costimulatory pathway in the regulation of immune responses to Leishmania major and Nippostrongylus brasiliensis infections.
Immunology letters 2003;89(2-3):193-9.
2003: Kanai Takanori; Totsuka Teruji; Uraushihara Koji; Makita Shin; Nakamura Tetsuya; Koganei Kazutaka; Fukushima Tsuneo; Akiba Hisaya; Yagita Hideo; Okumura Ko; Machida Utako; Iwai Hideyuki; Azuma Miyuki; Chen Lieping; Watanabe Mamoru
Blockade of B7-H1 suppresses the development of chronic intestinal inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(8):4156-63.
2003: Tsushima Fumihiko; Iwai Hideyuki; Otsuki Noriko; Abe Masaaki; Hirose Sachiko; Yamazaki Tomohide; Akiba Hisaya; Yagita Hideo; Takahashi Yuzo; Omura Ken; Okumura Ko; Azuma Miyuki
Preferential contribution of B7-H1 to programmed death-1-mediated regulation of hapten-specific allergic inflammatory responses.
European journal of immunology 2003;33(10):2773-82.
2003: Dan N; Kanai T; Totsuka T; Iiyama R; Yamazaki M; Sawada T; Miyata T; Yagita H; Okumura K; Watanabe M
Ameliorating effect of anti-Fas ligand MAb on wasting disease in murine model of chronic colitis.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(4):G754-60.
2003: Aramaki Osamu; Shirasugi Nozomu; Akiyama Yoshinobu; Shibutani Shintaro; Takayama Tadatoshi; Shimazu Motohide; Kitajima Masaki; Ikeda Yoshifumi; Okumura Ko; Yagita Hideo; Niimi Masanori
CD27/CD70, CD134/CD134 ligand, and CD30/CD153 pathways are independently essential for generation of regulatory cells after intratracheal delivery of alloantigen.
Transplantation 2003;76(5):772-6.
2003: Iwai Hideyuki; Abe Masaaki; Hirose Sachiko; Tsushima Fumihiko; Tezuka Katsunari; Akiba Hisaya; Yagita Hideo; Okumura Ko; Kohsaka Hitoshi; Miyasaka Nobuyuki; Azuma Miyuki
Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):2848-54.
2003: Tsuji Hideki; Kawaguchi Satoshi; Wada Takuro; Nagoya Satoshi; Inobe Manabu; Yagita Hideo; Okumura Ko; Yamashita Toshihiko; Uede Toshimitsu
Concurrent induction of T-cell activation and apoptosis of osteosarcoma cells by adenovirus-mediated B7-1/Fas chimeric gene transfer.
Cancer gene therapy 2003;10(9):717-25.
2003: Chakrabarty S; Nagata M; Yasuda H; Wen L; Nakayama M; Chowdhury S A; Yamada K; Jin Z; Kotani R; Moriyama H; Shimozato O; Yagita H; Yokono K
Critical roles of CD30/CD30L interactions in murine autoimmune diabetes.
Clinical and experimental immunology 2003;133(3):318-25.
2003: Saitoh Tatsuya; Nakayama Masafumi; Nakano Hiroyasu; Yagita Hideo; Yamamoto Naoki; Yamaoka Shoji
TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.
The Journal of biological chemistry 2003;278(38):36005-12.
2003: Tajima Atsushi; Tanaka Toshitaka; Ebata Tomohiko; Takeda Kazuyoshi; Kawasaki Akemi; Kelly Janice M; Darcy Phillip K; Vance Russell E; Raulet David H; Kinoshita Katsuyuki; Okumura Ko; Smyth Mark J; Yagita Hideo
Blastocyst MHC, a putative murine homologue of HLA-G, protects TAP-deficient tumor cells from natural killer cell-mediated rejection in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):1715-21.
2003: Youngnak Pornpan; Kozono Yuko; Kozono Haruo; Iwai Hideyuki; Otsuki Noriko; Jin Hisayo; Omura Ken; Yagita Hideo; Pardoll Drew M; Chen Lieping; Azuma Miyuki
Differential binding properties of B7-H1 and B7-DC to programmed death-1.
Biochemical and biophysical research communications 2003;307(3):672-7.
2003: Sakon Sachiko; Xue Xin; Takekawa Mutsuhiro; Sasazuki Tomonari; Okazaki Tatsuma; Kojima Yuko; Piao Jian-Hu; Yagita Hideo; Okumura Ko; Doi Takahiro; Nakano Hiroyasu
NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death.
The EMBO journal 2003;22(15):3898-909.
2003: Blazar Bruce R; Carreno Beatriz M; Panoskaltsis-Mortari Angela; Carter Laura; Iwai Yoshiko; Yagita Hideo; Nishimura Hiroyuki; Taylor Patricia A
Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-gamma-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1272-7.
2003: Kirii Yasuyuki; Inoue Tomomi; Yoshino Kohichiro; Kayagaki Nobuhiko; Yagita Hideo; Okumura Ko; Shibata Hiroaki; Yoshikawa Yasuhiro; Terao Keiji
Molecular cloning, functional characterization, and enzyme-linked immunosorbent assay of cynomolgus monkey Fas ligand.
Journal of immunological methods 2003;278(1-2):201-9.
2003: Harada Hiroshi; Salama Alan D; Sho Masayuki; Izawa Atsushi; Sandner Sigrid E; Ito Toshiro; Akiba Hisaya; Yagita Hideo; Sharpe Arlene H; Freeman Gordon J; Sayegh Mohamed H
The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity.
The Journal of clinical investigation 2003;112(2):234-43.
2003: Salek-Ardakani Shahram; Song Jianxun; Halteman Beth S; Jember Amha Gebre-Hiwot; Akiba Hisaya; Yagita Hideo; Croft Michael
OX40 (CD134) controls memory T helper 2 cells that drive lung inflammation.
The Journal of experimental medicine 2003;198(2):315-24.
2003: Iiyama R; Kanai T; Uraushihara K; Totsuka T; Nakamura T; Miyata T; Yagita H; Kushi A; Suzuki K; Tezuka K; Watanabe M
The role of inducible co-stimulator (ICOS)/B7-related protein-1 (B7RP-1) interaction in the functional development of Peyer's patches.
Immunology letters 2003;88(1):63-70.
2003: Salama Alan D; Chitnis Tanuja; Imitola Jaime; Ansari Mohammed Javeed I; Akiba Hisaya; Tushima Fumihiko; Azuma Miyuki; Yagita Hideo; Sayegh Mohamed H; Khoury Samia J
Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis.
The Journal of experimental medicine 2003;198(1):71-8.
2003: Ansari Mohammed Javeed I; Salama Alan D; Chitnis Tanuja; Smith R Neal; Yagita Hideo; Akiba Hisaya; Yamazaki Tomohide; Azuma Miyuki; Iwai Hideyuki; Khoury Samia J; Auchincloss Hugh; Sayegh Mohamed H
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.
The Journal of experimental medicine 2003;198(1):63-9.
2003: Shin Tahiro; Kennedy Gene; Gorski Kevin; Tsuchiya Haruo; Koseki Haruhiko; Azuma Miyuki; Yagita Hideo; Chen Lieping; Powell Jonathan; Pardoll Drew; Housseau Franck
Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor.
The Journal of experimental medicine 2003;198(1):31-8.
2003: Nakayama Masafumi; Harada Norihiro; Okumura Ko; Yagita Hideo
Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies.
Biochemical and biophysical research communications 2003;306(4):819-25.
2003: Yoshizawa Izumi; Mizuochi Toshiaki; Ogata Akio; Murakami Masahiro; Yagita Hideo; Takahashi Yoshimasa; Mizuochi Tsuguo; Takemori Toshitada; Tsunetsugu-Yokota Yasuko;
Studies on the generation and maintenance of mucosal cytotoxic T lymphocytes against human immunodeficiency virus type 1 Gag in mice.
AIDS research and human retroviruses 2003;19(6):469-79.
2003: Miyahira Yasushi; Katae Masaharu; Kobayashi Seiki; Takeuchi Tsutomu; Fukuchi Yoshinosuke; Abe Ryo; Okumura Ko; Yagita Hideo; Aoki Takashi
Critical contribution of CD28-CD80/CD86 costimulatory pathway to protection from Trypanosoma cruzi infection.
Infection and immunity 2003;71(6):3131-7.
2003: Shirasugi Nozomu; Akiyama Yoshinobu; Aramaki Osamu; Shibutani Sintaro; Matsumoto Kenji; Bashuda Hisashi; Yagita Hideo; Okumura Ko; Ikeda Yoshifumi; Niimi Masanori
Role of the CTLA4 pathway in hyporesponsiveness induced by intratracheal delivery of alloantigen.
Transplantation 2003;75(10):1636-9.
2003: Lee Kyung-Mi; Bhawan Sadhna; Majima Takashi; Wei Hairong; Nishimura Michael I; Yagita Hideo; Kumar Vinay
Cutting edge: the NK cell receptor 2B4 augments antigen-specific T cell cytotoxicity through CD48 ligation on neighboring T cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(10):4881-5.
2003: Blazar Bruce R; Sharpe Arlene H; Chen Andy I; Panoskaltsis-Mortari Angela; Lees Christopher; Akiba Hisaya; Yagita Hideo; Killeen Nigel; Taylor Patricia A
Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients.
Blood 2003;101(9):3741-8.
2003: Uno Kanako; Inukai Takeshi; Kayagaki Nobuhiko; Goi Kumiko; Sato Hiroki; Nemoto Atsushi; Takahashi Kazuya; Kagami Keiko; Yamaguchi Noriko; Yagita Hideo; Okumura Ko; Koyama-Okazaki Toshiko; Suzuki Toshio; Sugita Kanji; Nakazawa Shinpei
TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome-positive leukemia cells.
Blood 2003;101(9):3658-67.
2003: Hoshino Akihiko; Tanaka Yoshitaka; Akiba Hisaya; Asakura Yumiko; Mita Yasuo; Sakurai Takanobu; Takaoka Akiko; Nakaike Shiro; Ishii Naoto; Sugamura Kazuo; Yagita Hideo; Okumura Ko
Critical role for OX40 ligand in the development of pathogenic Th2 cells in a murine model of asthma.
European journal of immunology 2003;33(4):861-9.
2003: Totsuka T; Kanai T; Uraushihara K; Iiyama R; Yamazaki M; Akiba H; Yagita H; Okumura K; Watanabe M
Therapeutic effect of anti-OX40L and anti-TNF-alpha MAbs in a murine model of chronic colitis.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(4):G595-603.
2003: Yuan Xueli; Salama Alan D; Dong Victor; Schmitt Isabela; Najafian Nader; Chandraker Anil; Akiba Hisaya; Yagita Hideo; Sayegh Mohamed H
The role of the CD134-CD134 ligand costimulatory pathway in alloimmune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):2949-55.
2003: Miura Yoshiharu; Misawa Naoko; Kawano Yuji; Okada Hiroshi; Inagaki Yoshio; Yamamoto Naoki; Ito Mamoru; Yagita Hideo; Okumura Ko; Mizusawa Hidehiro; Koyanagi Yoshio
Tumor necrosis factor-related apoptosis-inducing ligand induces neuronal death in a murine model of HIV central nervous system infection.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2777-82.
2003: Miyahira Yasushi; Katae Masaharu; Takeda Kazuyoshi; Yagita Hideo; Okumura Ko; Kobayashi Seiki; Takeuchi Tsutomu; Kamiyama Tsuneo; Fukuchi Yoshinosuke; Aoki Takashi
Activation of natural killer T cells by alpha-galactosylceramide impairs DNA vaccine-induced protective immunity against Trypanosoma cruzi.
Infection and immunity 2003;71(3):1234-41.
2003: Totsuka Teruji; Kanai Takanori; Iiyama Ryoichi; Uraushihara Koji; Yamazaki Motomi; Okamoto Ryuichi; Hibi Toshifumi; Tezuka Katsunari; Azuma Miyuki; Akiba Hisaya; Yagita Hideo; Okumura Ko; Watanabe Mamoru
Ameliorating effect of anti-inducible costimulator monoclonal antibody in a murine model of chronic colitis.
Gastroenterology 2003;124(2):410-21.
2003: Okazaki Tatsuma; Sakon Sachiko; Sasazuki Tomonari; Sakurai Hiroaki; Doi Takahiro; Yagita Hideo; Okumura Ko; Nakano Hiroyasu
Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses.
Biochemical and biophysical research communications 2003;300(4):807-12.
2003: Smyth Mark J; Takeda Kazuyoshi; Hayakawa Yoshihiro; Peschon Jacques J; van den Brink Marcel R M; Yagita Hideo
Nature's TRAIL--on a path to cancer immunotherapy.
Immunity 2003;18(1):1-6.
2003: Seki Naoko; Hayakawa Yoshihiro; Brooks Alan D; Wine John; Wiltrout Robert H; Yagita Hideo; Tanner Jane E; Smyth Mark J; Sayers Thomas J
Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer.
Cancer research 2003;63(1):207-13.
2003: Nakayama Masafumi; Ishidoh Kazumi; Kojima Yuko; Harada Norihiro; Kominami Eiki; Okumura Ko; Yagita Hideo
Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(1):341-8.
2002: Moro Monica; Filippi Christophe; Gallard Alexandra; Malherbe Laurent; Foucras Gilles; Akiba Hisaya; Yagita Hideo; Guéry Jean-Charles; Glaichenhaus Nicolas
Blockade of CD86 in BALB/c mice infected with Leishmania major does not prevent the expansion of low avidity T cells.
European journal of immunology 2002;32(12):3566-75.
2002: Harada Norihiro; Nakayama Masafumi; Nakano Hiroyasu; Fukuchi Yoshinosuke; Yagita Hideo; Okumura Ko
Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells.
Biochemical and biophysical research communications 2002;299(3):488-93.
2002: Schmaltz Cornelius; Alpdogan Onder; Kappel Barry J; Muriglan Stephanie J; Rotolo Jimmy A; Ongchin Jennifer; Willis Lucy M; Greenberg Andrew S; Eng Jeffrey M; Crawford James M; Murphy George F; Yagita Hideo; Walczak Henning; Peschon Jacques J; van den Brink Marcel R M
T cells require TRAIL for optimal graft-versus-tumor activity.
Nature medicine 2002;8(12):1433-7.
2002: Yamazaki Tomohide; Akiba Hisaya; Iwai Hideyuki; Matsuda Hironori; Aoki Mami; Tanno Yuka; Shin Tahiro; Tsuchiya Haruo; Pardoll Drew M; Okumura Ko; Azuma Miyuki; Yagita Hideo
Expression of programmed death 1 ligands by murine T cells and APC.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5538-45.
2002: Ursini-Siegel Josie; Zhang Wenli; Altmeyer Anne; Hatada Eunice N; Do Richard K G; Yagita Hideo; Chen-Kiang Selina
TRAIL/Apo-2 ligand induces primary plasma cell apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5505-13.
2002: Smyth Mark J; Hayakawa Yoshihiro; Takeda Kazuyoshi; Yagita Hideo
New aspects of natural-killer-cell surveillance and therapy of cancer.
Nature reviews. Cancer 2002;2(11):850-61.
2002: Kayagaki Nobuhiko; Yamaguchi Noriko; Abe Masaaki; Hirose Sachiko; Shirai Toshikazu; Okumura Ko; Yagita Hideo
Suppression of antibody production by TNF-related apoptosis-inducing ligand (TRAIL).
Cellular immunology 2002;219(2):82-91.
2002: Bouchet Delphine; Tesson Laurent; Ménoret Séverine; Charreau Beatrice; Mathieu Patrick; Yagita Hideo; Duisit Ghislaine; Anegon Ignacio
Differential sensitivity of endothelial cells of various species to apoptosis induced by gene transfer of Fas ligand: role of FLIP levels.
Molecular medicine (Cambridge, Mass.) 2002;8(10):612-23.
2002: Iwai Hideyuki; Kozono Yuko; Hirose Sachiko; Akiba Hisaya; Yagita Hideo; Okumura Ko; Kohsaka Hitoshi; Miyasaka Nobuyuki; Azuma Miyuki
Amelioration of collagen-induced arthritis by blockade of inducible costimulator-B7 homologous protein costimulation.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4332-9.
2002: Schmitt Michael; Taniguchi Masanori; Yoshida Toshimichi; Miyahara Yoshihiro; Gu Xiaogang; Mukai Katanori; Yagita Hideo; Dohner Hartmut; Shiku Hiroshi
Rapid lethality of hosts by interleukin-12 following H-2 compatible allogeneic bone marrow transplantation: Reminiscence of gut-associated acute graft-versus-host reaction.
International journal of oncology 2002;21(4):795-801.
2002: Iwai Yoshiko; Okazaki Taku; Nishimura Hiroyuki; Kawasaki Akemi; Yagita Hideo; Honjo Tasuku
Microanatomical localization of PD-1 in human tonsils.
Immunology letters 2002;83(3):215-20.
2002: Akiyama Yoshinobu; Shirasugi Nozomu; Uchida Norio; Matsumoto Kenji; Kitajima Masaki; Bashuda Hisashi; Yagita Hideo; Okumura Ko; Aramaki Osamu; Niimi Masanori
B7/CTLA4 pathway is essential for generating regulatory cells after intratracheal delivery of alloantigen in mice.
Transplantation 2002;74(5):732-8.
2002: Katae Masaharu; Miyahira Yasushi; Takeda Kazuyoshi; Matsuda Hironori; Yagita Hideo; Okumura Ko; Takeuchi Tsutomu; Kamiyama Tsuneo; Ohwada Akihiko; Fukuchi Yoshinosuke; Aoki Takashi
Coadministration of an interleukin-12 gene and a Trypanosoma cruzi gene improves vaccine efficacy.
Infection and immunity 2002;70(9):4833-40.
2002: Hayakawa Yoshihiro; Takeda Kazuyoshi; Yagita Hideo; Smyth Mark J; Van Kaer Luc; Okumura Ko; Saiki Ikuo
IFN-gamma-mediated inhibition of tumor angiogenesis by natural killer T-cell ligand, alpha-galactosylceramide.
Blood 2002;100(5):1728-33.
2002: Kojima Yuko; Kawasaki-Koyanagi Akemi; Sueyoshi Noriyoshi; Kanai Atsushi; Yagita Hideo; Okumura Ko
Localization of Fas ligand in cytoplasmic granules of CD8+ cytotoxic T lymphocytes and natural killer cells: participation of Fas ligand in granule exocytosis model of cytotoxicity.
Biochemical and biophysical research communications 2002;296(2):328-36.
2002: Sasazuki Tomonari; Sawada Taisuke; Sakon Sachiko; Kitamura Toshio; Kishi Takuma; Okazaki Tatsuma; Katano Mitsuo; Tanaka Masao; Watanabe Mamoru; Yagita Hideo; Okumura Ko; Nakano Hiroyasu
Identification of a novel transcriptional activator, BSAC, by a functional cloning to inhibit tumor necrosis factor-induced cell death.
The Journal of biological chemistry 2002;277(32):28853-60.
2002: Tian Lina; Guo Weihong; Yuan Zhengwei; Lui Vincent C H; Chan Jacqueline K Y; Yagita Hideo; Akiba Hisaya; Dallman Margaret; Tam Paul K H
Association of the CD134/CD134L costimulatory pathway with acute rejection of small bowel allograft.
Transplantation 2002;74(1):133-8.
2002: Kim Ja-Young; Kim Yun-Hee; Chang Inik; Kim Sunshin; Pak Youngmi Kim; Oh Byung-Ha; Yagita Hideo; Jung Yong Keun; Oh Young Joon; Lee Myung-Shik
Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis.
Oncogene 2002;21(20):3139-48.
2002: Seko Yoshinori; Ishiyama Shigeru; Nishikawa Toshiro; Kasajima Takeshi; Hiroe Michiaki; Suzuki Shin; Ishiwata Sugao; Kawai Sachio; Tanaka Yuetsu; Azuma Miyuki; Kobata Tetsuji; Yagita Hideo; Okumura Ko; Nagai Ryozo
Expression of tumor necrosis factor ligand superfamily costimulatory molecules CD27L, CD30L, OX40L and 4-1BBL in the heart of patients with acute myocarditis and dilated cardiomyopathy.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2002;11(3):166-70.
2002: Nakayama Maki; Nagata Masao; Yasuda Hisafumi; Arisawa Kenji; Kotani Reiko; Yamada Katsumi; Chowdhury Shahead Ali; Chakrabarty Sagarika; Jin Zhen Zi; Yagita Hideo; Yokono Koichi; Kasuga Masato
Fas/Fas ligand interactions play an essential role in the initiation of murine autoimmune diabetes.
Diabetes 2002;51(5):1391-7.
2002: Kelly Janice M; Takeda Kazuyoshi; Darcy Phillip K; Yagita Hideo; Smyth Mark J
A role for IFN-gamma in primary and secondary immunity generated by NK cell-sensitive tumor-expressing CD80 in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4472-9.
2002: Seko Yoshinori; Kayagaki Nobuhiko; Seino Ken-ichiro; Yagita Hideo; Okumura Ko; Nagai Ryozo
Role of Fas/FasL pathway in the activation of infiltrating cells in murine acute myocarditis caused by Coxsackievirus B3.
Journal of the American College of Cardiology 2002;39(8):1399-403.
2002: Zuñiga Elina; Motran Claudia C; Montes Carolina L; Yagita Hideo; Gruppi Adriana
Trypanosoma cruzi infection selectively renders parasite-specific IgG+ B lymphocytes susceptible to Fas/Fas ligand-mediated fratricide.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):3965-73.
2002: Smyth Mark J; Crowe Nadine Y; Hayakawa Yoshihiro; Takeda Kazuyoshi; Yagita Hideo; Godfrey Dale I
NKT cells - conductors of tumor immunity?
Current opinion in immunology 2002;14(2):165-71.
2002: Sugita Junichi; Ohtani Haruo; Mizoi Takayuki; Saito Kazuya; Shiiba Kenichi; Sasaki Iwao; Matsuno Seiki; Yagita Hideo; Miyazawa Masaaki; Nagura Hiroshi
Close association between Fas ligand (FasL; CD95L)-positive tumor-associated macrophages and apoptotic cancer cells along invasive margin of colorectal carcinoma: a proposal on tumor-host interactions.
Japanese journal of cancer research : Gann 2002;93(3):320-8.
2002: Yamada Masato; Yagita Hideo; Inoue Hideko; Takanashi Tsuyoshi; Matsuda Hironori; Munechika Eiko; Kanamaru Yutaka; Shirato Isao; Tomino Yasuhiko; Matushima Kouji; Okumura Ko; Hashimoto Hiroshi
Selective accumulation of CCR4+ T lymphocytes into renal tissue of patients with lupus nephritis.
Arthritis and rheumatism 2002;46(3):735-40.
2002: Futagawa Toshiro; Akiba Hisaya; Kodama Tomohiro; Takeda Kazuyoshi; Hosoda Yasuyuki; Yagita Hideo; Okumura Ko
Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells.
International immunology 2002;14(3):275-86.
2002: Watanabe Tomohiro; Yoshida Masaru; Shirai Yasuhiko; Yamori Masashi; Yagita Hideo; Itoh Toshiyuki; Chiba Tsutomu; Kita Toru; Wakatsuki Yoshio
Administration of an antigen at a high dose generates regulatory CD4+ T cells expressing CD95 ligand and secreting IL-4 in the liver.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(5):2188-99.
2002: Kim Sunshin; Ki Ja Young; Lee Tae H; Suk Kyungho; Cha Hoon-Suk; Koh Eun-Mi; Yagita Hideo; Lee Myung-Shik
Soluble Fas ligand-susceptible "memory" cells in mice but not in human: potential role of soluble Fas ligand in deletion of auto-reactive cells.
Autoimmunity 2002;35(1):15-20.
2002: Smyth Mark J; Crowe Nadine Y; Pellicci Daniel G; Kyparissoudis Konstantinos; Kelly Janice M; Takeda Kazuyoshi; Yagita Hideo; Godfrey Dale I
Sequential production of interferon-gamma by NK1.1(+) T cells and natural killer cells is essential for the antimetastatic effect of alpha-galactosylceramide.
Blood 2002;99(4):1259-66.
2002: Cretney Erika; Takeda Kazuyoshi; Yagita Hideo; Glaccum Moira; Peschon Jacques J; Smyth Mark J
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1356-61.
2002: Kagaya Fumie; Hori Junko; Kamiya Kazutaka; Kaji Yuichi; Oshika Tetsuro; Amano Shiro; Yamagami Satoru; Tsuru Tadahiko; Tanaka Sumiyoshi; Matsuda Hironori; Yagita Hideo; Okumura Ko
Inhibition of murine corneal allograft rejection by treatment with antibodies to CD80 and CD86.
Experimental eye research 2002;74(1):131-9.
2002: Takeda Kazuyoshi; Smyth Mark J; Cretney Erika; Hayakawa Yoshihiro; Kayagaki Nobuhiko; Yagita Hideo; Okumura Ko
Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development.
The Journal of experimental medicine 2002;195(2):161-9.
2002: Nakayama Masafumi; Ishidoh Kazumi; Kayagaki Nobuhiko; Kojima Yuko; Yamaguchi Noriko; Nakano Hiroyasu; Kominami Eiki; Okumura Ko; Yagita Hideo
Multiple pathways of TWEAK-induced cell death.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):734-43.
2002: Kelly Janice M; Darcy Phillip K; Markby Jessica L; Godfrey Dale I; Takeda Kazuyoshi; Yagita Hideo; Smyth Mark J
Induction of tumor-specific T cell memory by NK cell-mediated tumor rejection.
Nature immunology 2002;3(1):83-90.
2001: Takeda K; Smyth M J; Cretney E; Hayakawa Y; Yamaguchi N; Yagita H; Okumura K
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth.
Cellular immunology 2001;214(2):194-200.
2001: Seko Y; Takahashi N; Oshima H; Shimozato O; Akiba H; Takeda K; Kobata T; Yagita H; Okumura K; Azuma M; Nagai R
Expression of tumour necrosis factor (TNF) ligand superfamily co-stimulatory molecules CD30L, CD27L, OX40L, and 4-1BBL in murine hearts with acute myocarditis caused by Coxsackievirus B3.
The Journal of pathology 2001;195(5):593-603.
2001: Sato K; Hida S; Takayanagi H; Yokochi T; Kayagaki N; Takeda K; Yagita H; Okumura K; Tanaka N; Taniguchi T; Ogasawara K
Antiviral response by natural killer cells through TRAIL gene induction by IFN-alpha/beta.
European journal of immunology 2001;31(11):3138-46.
2001: Tada K; Okazaki T; Sakon S; Kobarai T; Kurosawa K; Yamaoka S; Hashimoto H; Mak T W; Yagita H; Okumura K; Yeh W C; Nakano H
Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death.
The Journal of biological chemistry 2001;276(39):36530-4.
2001: Khanolkar A; Yagita H; Cannon M J
Preferential utilization of the perforin/granzyme pathway for lysis of Epstein-Barr virus-transformed lymphoblastoid cells by virus-specific CD4+ T cells.
Virology 2001;287(1):79-88.
2001: Okazaki T; Nakao A; Nakano H; Takahashi F; Takahashi K; Shimozato O; Takeda K; Yagita H; Okumura K
Impairment of bleomycin-induced lung fibrosis in CD28-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):1977-81.
2001: Borges V M; Falcão H; Leite-Júnior J H; Alvim L; Teixeira G P; Russo M; Nóbrega A F; Lopes M F; Rocco P M; Davidson W F; Linden R; Yagita H; Zin W A; DosReis G A
Fas ligand triggers pulmonary silicosis.
The Journal of experimental medicine 2001;194(2):155-64.
2001: Hayakawa Y; Takeda K; Yagita H; Kakuta S; Iwakura Y; Van Kaer L; Saiki I; Okumura K
Critical contribution of IFN-gamma and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of alpha-galactosylceramide.
European journal of immunology 2001;31(6):1720-7.
2001: Hayakawa Y; Takeda K; Yagita H; Van Kaer L; Saiki I; Okumura K
Differential regulation of Th1 and Th2 functions of NKT cells by CD28 and CD40 costimulatory pathways.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):6012-8.
2001: Fujimoto H; Tanaka Y; Liu Z J; Yagita H; Okumura K; Kosugi A; Morinobu A; Umehara H; Yamamura H; Minami Y
Down-regulation of alpha6 integrin, an anti-oncogene product, by functional cooperation of H-Ras and c-Myc.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(4):337-43.
2001: Miura Y; Misawa N; Maeda N; Inagaki Y; Tanaka Y; Ito M; Kayagaki N; Yamamoto N; Yagita H; Mizusawa H; Koyanagi Y
Critical contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to apoptosis of human CD4+ T cells in HIV-1-infected hu-PBL-NOD-SCID mice.
The Journal of experimental medicine 2001;193(5):651-60.
2001: Chitnis T; Najafian N; Abdallah K A; Dong V; Yagita H; Sayegh M H; Khoury S J
CD28-independent induction of experimental autoimmune encephalomyelitis.
The Journal of clinical investigation 2001;107(5):575-83.
2001: Shirasugi N; Ikeda Y; Akiyama Y; Matsumoto K; Hamano K; Esato K; Bashuda H; Yagita H; Okumura K; Takami H; Kodaira S; Niimi M
Induction of hyporesponsiveness to fully allogeneic cardiac grafts by intratracheal delivery of alloantigen.
Transplantation 2001;71(4):561-4.
2001: Nohara C; Akiba H; Nakajima A; Inoue A; Koh C S; Ohshima H; Yagita H; Mizuno Y; Okumura K
Amelioration of experimental autoimmune encephalomyelitis with anti-OX40 ligand monoclonal antibody: a critical role for OX40 ligand in migration, but not development, of pathogenic T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):2108-15.
2001: Takeda K; Hayakawa Y; Smyth M J; Kayagaki N; Yamaguchi N; Kakuta S; Iwakura Y; Yagita H; Okumura K
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells.
Nature medicine 2001;7(1):94-100.
2000: Fujihira K; Nagata M; Moriyama H; Yasuda H; Arisawa K; Nakayama M; Maeda S; Kasuga M; Okumura K; Yagita H; Yokono K
Suppression and acceleration of autoimmune diabetes by neutralization of endogenous interleukin-12 in NOD mice.
Diabetes 2000;49(12):1998-2006.
2000: Shirasugi N; Matsumoto S; Hamano K; Esato K; Matsumoto K; Bashuda H; Yagita H; Okumura K; Ikeda Y; Takami H; Kodaira S; Niimi M
Survival of fully allogeneic cardiac allografts induced by delivery of alloantigen via respiratory mucosa is abrogated by blockade of the B7 pathway.
Transplantation proceedings 2000;32(7):2034.
2000: Nakayama M; Kayagaki N; Yamaguchi N; Okumura K; Yagita H
Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicity.
The Journal of experimental medicine 2000;192(9):1373-80.
2000: Yoshioka T; Nakajima A; Akiba H; Ishiwata T; Asano G; Yoshino S; Yagita H; Okumura K
Contribution of OX40/OX40 ligand interaction to the pathogenesis of rheumatoid arthritis.
European journal of immunology 2000;30(10):2815-23.
2000: Trinité B; Voisine C; Yagita H; Josien R
A subset of cytolytic dendritic cells in rat.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(8):4202-8.
2000: Nagao F; Suzui M; Takeda K; Yagita H; Okumura K
Mobilization of NK cells by exercise: downmodulation of adhesion molecules on NK cells by catecholamines.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(4):R1251-6.
2000: Nakajima A; Oshima H; Nohara C; Morimoto S; Yoshino S; Kobata T; Yagita H; Okumura K
Involvement of CD70-CD27 interactions in the induction of experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 2000;109(2):188-96.
2000: Seko Y; Takahashi N; Tada Y; Yagita H; Okumura K; Nagai R
Restricted usage of T-cell receptor Vgamma-Vdelta genes and expression of costimulatory molecules in Takayasu's arteritis.
International journal of cardiology 2000;75 Suppl 1():S77-83; discussion S85-7.
2000: Hattori K; Hirano T; Oshimi K; Yagita H; Okumura K
A metalloproteinase inhibitor prevents acute graft-versus-host disease while preserving the graft-versus-leukaemia effect of allogeneic bone marrow transplantation.
Leukemia & lymphoma 2000;38(5-6):553-61.
2000: Saitoh A; Kawanabe T; Weidong H; Kayagaki N; Kawamura T; Yagita H; Okumura K; Shimada S
Selective upregulation of fibroblast Fas ligand expression, and prolongation of Fas/Fas ligand-mediated skin allograft survival, by retinoic acid: the skin as a retinoide-inducible immune privilege site.
The Journal of investigative dermatology 2000;115(2):154-61.
2000: Sayers T J; Brooks A D; Seki N; Smyth M J; Yagita H; Blazar B R; Malyguine A M
T cell lysis of murine renal cancer: multiple signaling pathways for cell death via Fas.
Journal of leukocyte biology 2000;68(1):81-6.
2000: Takeda K; Hayakawa Y; Atsuta M; Hong S; Van Kaer L; Kobayashi K; Ito M; Yagita H; Okumura K
Relative contribution of NK and NKT cells to the anti-metastatic activities of IL-12.
International immunology 2000;12(6):909-14.
2000: Luo Z; Gotoh M; Grochowiecki T; Tanaka T; Kimura F; Kawashima H; Yagita H; Okumura K; Miyasaka M
Anergic T cells generated in vitro suppress rejection response to islet allografts.
Transplantation 2000;69(10):2144-8.
2000: Takeda K; Hayakawa Y; Van Kaer L; Matsuda H; Yagita H; Okumura K
Critical contribution of liver natural killer T cells to a murine model of hepatitis.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5498-503.
2000: Grochowiecki T; Gotoh M; Dono K; Takeda Y; Sakon M; Yagita H; Okumura K; Miyasaka M; Monden M
Induction of unresponsiveness to islet xenograft by MMC treatment of graft and blockage of LFA-1/ICAM-1 pathway.
Transplantation 2000;69(8):1567-71.
2000: Iwao M; Fukada S; Harada T; Tsujikawa K; Yagita H; Hiramine C; Miyagoe Y; Takeda S; Yamamoto H
Interaction of merosin (laminin 2) with very late activation antigen-6 is necessary for the survival of CD4+ CD8+ immature thymocytes.
Immunology 2000;99(4):481-8.
2000: Satake Y; Akiba H; Takeda K; Atsuta M; Yagita H; Okumura K
Characterization of rat OX40 ligand by monoclonal antibody.
Biochemical and biophysical research communications 2000;270(3):1041-8.
2000: Tsukada N; Akiba H; Kobata T; Aizawa Y; Yagita H; Okumura K
Blockade of CD134 (OX40)-CD134L interaction ameliorates lethal acute graft-versus-host disease in a murine model of allogeneic bone marrow transplantation.
Blood 2000;95(7):2434-9.
2000: Shinohara H; Yagita H; Ikawa Y; Oyaizu N
Fas drives cell cycle progression in glioma cells via extracellular signal-regulated kinase activation.
Cancer research 2000;60(6):1766-72.
2000: Kim S; Kim K A; Hwang D Y; Lee T H; Kayagaki N; Yagita H; Lee M S
Inhibition of autoimmune diabetes by Fas ligand: the paradox is solved.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(6):2931-6.
2000: Nakajima A; Hirai H; Kayagaki N; Yoshino S; Hirose S; Yagita H; Okumura K
Treatment of lupus in NZB/W F1 mice with monoclonal antibody against Fas ligand.
Journal of autoimmunity 2000;14(2):151-7.
2000: Kawamura T; Azuma M; Kayagaki N; Shimada S; Yagita H; Okumura K
Fas/Fas ligand-mediated apoptosis of murine Langerhans cells.
Journal of dermatological science 2000;22(2):96-101.
2000: Takeda K; Oshima H; Hayakawa Y; Akiba H; Atsuta M; Kobata T; Kobayashi K; Ito M; Yagita H; Okumura K
CD27-mediated activation of murine NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(4):1741-5.
2000: Akiba H; Miyahira Y; Atsuta M; Takeda K; Nohara C; Futagawa T; Matsuda H; Aoki T; Yagita H; Okumura K
Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis.
The Journal of experimental medicine 2000;191(2):375-80.
1999: Shirakata Y; Ishii K; Yagita H; Okumura K; Taniguchi M; Takemori T
Distinct subcellular localization and substrate specificity of extracellular signal-regulated kinase in B cells upon stimulation with IgM and CD40.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6589-97.
1999: Inoue A; Koh C S; Yamazaki M; Yagita H
Effect of anti-B7-1 and anti-B7-2 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(11):6180-6.
1999: Liu Z J; Tanaka Y; Fujimoto H; Mine S; Morinobu A; Yagita H; Okumura K; Oishi I; Udagawa J; Yamamura H; Minami Y
A novel role for H-Ras in the regulation of very late antigen-4 integrin and VCAM-1 via c-Myc-dependent and -independent mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(9):4901-8.
1999: Morita H; Takeda K; Yagita H; Okumura K
Immunosuppressive effect of leukotriene B(4) receptor antagonist in vitro.
Biochemical and biophysical research communications 1999;264(2):321-6.
1999: Kawamura T; Azuma M; Kayagaki N; Shimada S; Yagita H; Okumura K
Fas/Fas ligand-mediated elimination of antigen-bearing Langerhans cells in draining lymph nodes.
The British journal of dermatology 1999;141(2):201-5.
1999: Nakano H; Sakon S; Koseki H; Takemori T; Tada K; Matsumoto M; Munechika E; Sakai T; Shirasawa T; Akiba H; Kobata T; Santee S M; Ware C F; Rennert P D; Taniguchi M; Yagita H; Okumura K
Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9803-8.
1999: Seko Y; Takahashi N; Oshima H; Shimozato O; Akiba H; Kobata T; Yagita H; Okumura K; Azuma M; Yazaki Y
Expression of tumour necrosis factor (TNF) receptor/ligand superfamily co-stimulatory molecules CD40, CD30L, CD27L, and OX40L in murine hearts with chronic ongoing myocarditis caused by coxsackie virus B3.
The Journal of pathology 1999;188(4):423-30.
1999: Kayagaki N; Yamaguchi N; Nakayama M; Takeda K; Akiba H; Tsutsui H; Okamura H; Nakanishi K; Okumura K; Yagita H
Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(4):1906-13.
1999: Hattori K; Hirano T; Ushiyama C; Miyajima H; Yamakawa N; Ikeda S; Yoshino K; Tateno M; Oshimi K; Kayagaki N; Yagita H; Okumura K
A metalloproteinase inhibitor prevents acute graft-versus-host disease in mice after bone marrow transplantation.
Bone marrow transplantation 1999;23(12):1283-9.
1999: Akiba H; Oshima H; Takeda K; Atsuta M; Nakano H; Nakajima A; Nohara C; Yagita H; Okumura K
CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7058-66.
1999: Seko Y; Takahashi N; Yagita H; Okumura K; Azuma M; Yazaki Y
Effects of in vivo administration of anti-B7-1/B7-2 monoclonal antibodies on the survival of mice with chronic ongoing myocarditis caused by Coxsackievirus B3.
The Journal of pathology 1999;188(1):107-12.
1999: Kayagaki N; Yamaguchi N; Nakayama M; Eto H; Okumura K; Yagita H
Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs.
The Journal of experimental medicine 1999;189(9):1451-60.
1999: Suzuki N; Nakajima A; Yoshino S; Matsushima K; Yagita H; Okumura K
Selective accumulation of CCR5+ T lymphocytes into inflamed joints of rheumatoid arthritis.
International immunology 1999;11(4):553-9.
1999: Hattori K; Hirano T; Miyajima H; Yamakawa N; Ikeda S; Yoshino K; Tateno M; Oshimi K; Kayagaki N; Yagita H; Okumura K
A metalloproteinase inhibitor prevents acute graft-versus-host disease while preserving the graft-versus-leukaemia effect of allogeneic bone marrow transplantation.
British journal of haematology 1999;105(1):303-12.
1999: Kodama T; Takeda K; Shimozato O; Hayakawa Y; Atsuta M; Kobayashi K; Ito M; Yagita H; Okumura K
Perforin-dependent NK cell cytotoxicity is sufficient for anti-metastatic effect of IL-12.
European journal of immunology 1999;29(4):1390-6.
1999: Tsukada N; Kobata T; Aizawa Y; Yagita H; Okumura K
Graft-versus-leukemia effect and graft-versus-host disease can be differentiated by cytotoxic mechanisms in a murine model of allogeneic bone marrow transplantation.
Blood 1999;93(8):2738-47.
1999: Takada T; Kato K; Yagita H; Hamada H; Okumura K
Effects of immunization with tumor cells double transfected with interleukin-2 (IL-2) and interleukin-12 (IL-12) genes on artificial metastasis of colon26 cells in BALB/c mice.
Clinical & experimental metastasis 1999;17(2):125-30.
1999: Shimozato O; Takeda K; Yagita H; Okumura K
Expression of CD30 ligand (CD153) on murine activated T cells.
Biochemical and biophysical research communications 1999;256(3):519-26.
1999: Kayagaki N; Yamaguchi N; Nakayama M; Kawasaki A; Akiba H; Okumura K; Yagita H
Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(5):2639-47.
1999: Grochowiecki T; Gotoh M; Dono K; Takeda Y; Ohzato H; Okuyama M; Shimizu J; Kimura F; He L; Nagano H; Nakamori S; Umeshita K; Sakon M; Yagita H; Okumura K; Miyasaka; Monden M
Pretreatment of islets with mitomycin C and blockage of costimulatory signal induces unresponsiveness to islet xenografts.
Transplantation proceedings 1999;31(1-2):925.
1999: Kawahara T; Yagita H; Okumura K; Futagawa S
T cell-mediated effector mechanisms in the rejection of allogeneically transplanted hepatocytes.
Transplantation proceedings 1999;31(1-2):830-1.
1999: Luo Z; Gotoh M; Grochowiecki T; Tanaka T; Kimura F; Kawashima H; Yagita H; Okumura K; Miyasaka M
Anergic cells generated in vitro suppress rejection response to islet allografts.
Transplantation proceedings 1999;31(1-2):623.
1999: Kim Y H; Kim S; Kim K A; Yagita H; Kayagaki N; Kim K W; Lee M S
Apoptosis of pancreatic beta-cells detected in accelerated diabetes of NOD mice: no role of Fas-Fas ligand interaction in autoimmune diabetes.
European journal of immunology 1999;29(2):455-65.
1999: Takahashi N; Seko Y; Azuma M; Yagita H; Okumura K; Yazaki Y
Evidence of cell-mediated cardiac myocyte injury involved in the heart failure of a patient with progressive systemic sclerosis.
Japanese circulation journal 1999;63(1):68-72.
1998: Liu Z J; Tanaka Y; Mine S; Morinobu A; Yagita H; Okumura K; Taniguchi T; Yamamura H; Minami Y
Functional cooperation of cyclin C and c-Myc in mediating homotypic cell adhesion via very late antigen-4 activation and vascular cell adhesion molecule-1 induction.
Blood 1998;92(12):4700-11.
1998: Seino K; Iwabuchi K; Kayagaki N; Miyata R; Nagaoka I; Matsuzawa A; Fukao K; Yagita H; Okumura K
Chemotactic activity of soluble Fas ligand against phagocytes.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4484-8.
1998: Akiba H; Atsuta M; Yagita H; Okumura K
Identification of rat OX40 ligand by molecular cloning.
Biochemical and biophysical research communications 1998;251(1):131-6.
1998: Kawahara T; Yagita H; Kasai S; Sawa M; Kato K; Okumura K; Futagawa S; Mito M
Allogeneic hepatocyte transplantation: contribution of Fas-Fas ligand interaction to allogeneic hepatocyte rejection.
Journal of gastroenterology and hepatology 1998;13 Suppl():S119-23.
1998: Hibino S; Kato K; Kudoh S; Yagita H; Okumura K
Tenascin suppresses CD3-mediated T cell activation.
Biochemical and biophysical research communications 1998;250(1):119-24.
1998: Seko Y; Takahashi N; Azuma M; Yagita H; Okumura K; Yazaki Y
Expression of costimulatory molecule CD40 in murine heart with acute myocarditis and reduction of inflammation by treatment with anti-CD40L/B7-1 monoclonal antibodies.
Circulation research 1998;83(4):463-9.
1998: Nakajima A; Kodama T; Morimoto S; Azuma M; Takeda K; Oshima H; Yoshino S; Yagita H; Okumura K
Antitumor effect of CD40 ligand: elicitation of local and systemic antitumor responses by IL-12 and B7.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1901-7.
1998: Park C S; Yashiro Y; Tai X G; Toyo-oka K; Hamaoka T; Yagita H; Okumura K; Neben S; Fujiwara H
Differential involvement of a Fas-CPP32-like protease pathway in apoptosis of TCR/CD9-costimulated, naive T cells and TCR-restimulated, activated T cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(12):5790-6.
1998: Sekine C; Yagita H; Miyasaka N; Okumura K
Expression and function of CD40 in rheumatoid arthritis synovium.
The Journal of rheumatology 1998;25(6):1048-53.
1998: Hattori K; Hirano T; Miyajima H; Yamakawa N; Tateno M; Oshimi K; Kayagaki N; Yagita H; Okumura K
Differential effects of anti-Fas ligand and anti-tumor necrosis factor alpha antibodies on acute graft-versus-host disease pathologies.
Blood 1998;91(11):4051-5.
1998: Akiba H; Nakano H; Nishinaka S; Shindo M; Kobata T; Atsuta M; Morimoto C; Ware C F; Malinin N L; Wallach D; Yagita H; Okumura K
CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase.
The Journal of biological chemistry 1998;273(21):13353-8.
1998: Ohtsuka Y; Udaka K; Yamashiro Y; Yagita H; Okumura K
Dystrophin acts as a transplantation rejection antigen in dystrophin-deficient mice: implication for gene therapy.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4635-40.
1998: Oshima H; Nakano H; Nohara C; Kobata T; Nakajima A; Jenkins N A; Gilbert D J; Copeland N G; Muto T; Yagita H; Okumura K
Characterization of murine CD70 by molecular cloning and mAb.
International immunology 1998;10(4):517-26.
1998: Ohta Y; Gotoh M; Ohzato H; Fukuzaki T; Nishihara M; Dono K; Umeshita K; Sakon M; Yagita H; Okumura K; Tanaka T; Kawashima H; Miyasaka M; Monden M
Direct antigen presentation through binding of donor intercellular adhesion molecule-1 to recipient lymphocyte function-associated antigen-1 molecules in xenograft rejection.
Transplantation 1998;65(8):1094-100.
1998: Takeda Y; Gotoh M; Dono K; Nishihara M; Grochowiecki T; Kimura F; Yoshida T; Ohta Y; Ota H; Ohzato H; Umeshita K; Takeda T; Matsuura N; Sakon M; Kayagaki N; Yagita H; Okumura K; Miyasaka M; Monden M
Protection of islet allografts transplanted together with Fas ligand expressing testicular allografts.
Diabetologia 1998;41(3):315-21.
1998: Seko Y; Takahashi N; Azuma M; Yagita H; Okumura K; Yazaki Y
Effects of in vivo administration of anti-B7-1/B7-2 monoclonal antibodies on murine acute myocarditis caused by coxsackievirus B3.
Circulation research 1998;82(5):613-8.
1998: Nakano H; Shindo M; Sakon S; Nishinaka S; Mihara M; Yagita H; Okumura K
Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3537-42.
1998: Shindo M; Nakano H; Kuroyanagi H; Shirasawa T; Mihara M; Gilbert D J; Jenkins N A; Copeland N G; Yagita H; Okumura K
cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2.
Biochemical and biophysical research communications 1998;244(1):285-92.
1998: Seko Y; Takahashi N; Ishiyama S; Nishikawa T; Kasajima T; Hiroe M; Suzuki S; Ishiwata S; Kawai S; Azuma M; Yagita H; Okumura K; Yazaki Y
Expression of costimulatory molecules B7-1, B7-2, and CD40 in the heart of patients with acute myocarditis and dilated cardiomyopathy.
Circulation 1998;97(7):637-9.
1998: Kawamura T; Takeda K; Mendiratta S K; Kawamura H; Van Kaer L; Yagita H; Abo T; Okumura K
Critical role of NK1+ T cells in IL-12-induced immune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):16-9.
1998: Shindo M; Nakano H; Sakon S; Yagita H; Mihara M; Okumura K
Assignment of IkappaB kinase beta (IKBKB) to human chromosome band 8p12-->p11 by in situ hybridization.
Cytogenetics and cell genetics 1998;82(1-2):32-3.
1997: Tsunetsugu-Yokota Y; Yasuda S; Sugimoto A; Yagi T; Azuma M; Yagita H; Akagawa K; Takemori T
Efficient virus transmission from dendritic cells to CD4+ T cells in response to antigen depends on close contact through adhesion molecules.
Virology 1997;239(2):259-68.
1997: Seko Y; Sato O; Takagi A; Tada Y; Matsuo H; Yagita H; Okumura K; Yazaki Y
Perforin-secreting killer cell infiltration in the aortic tissue of patients with atherosclerotic aortic aneurysm.
Japanese circulation journal 1997;61(12):965-70.
1997: Nishihara M; Gotoh M; Ohzato H; Ohta Y; Luo Z; Dono K; Umeshita K; Sakon M; Monden M; Yagita H; Okumura K; Miyasaka M
Awareness of donor alloantigens in antiadhesion therapy induces antigen-specific unresponsiveness to islet allografts.
Transplantation 1997;64(7):965-70.
1997: Seino K; Kayagaki N; Tsukada N; Fukao K; Yagita H; Okumura K
Transplantation of CD95 ligand-expressing grafts: influence of transplantation site and difficulty in protecting allo- and xenografts.
Transplantation 1997;64(7):1050-4.
1997: Kawahara T; Kasai S; Yagita H; Sawa M; Kato K; Azuma M; Nakajima A; Okumura K; Futagawa S; Mito M
Critical role of Fas/Fas ligand interaction in CD28-independent pathway of allogeneic murine hepatocyte rejection.
Hepatology (Baltimore, Md.) 1997;26(4):944-8.
1997: Seino K; Kayagaki N; Takeda K; Fukao K; Okumura K; Yagita H
Contribution of Fas ligand to T cell-mediated hepatic injury in mice.
Gastroenterology 1997;113(4):1315-22.
1997: Seko Y; Takahashi N; Yagita H; Okumura K; Yazaki Y
Expression of cytokine mRNAs in murine hearts with acute myocarditis caused by coxsackievirus b3.
The Journal of pathology 1997;183(1):105-8.
1997: Oyaizu N; Kayagaki N; Yagita H; Pahwa S; Ikawa Y
Requirement of cell-cell contact in the induction of Jurkat T cell apoptosis: the membrane-anchored but not soluble form of FasL can trigger anti-CD3-induced apoptosis in Jurkat T cells.
Biochemical and biophysical research communications 1997;238(2):670-5.
1997: Hirano N; Takahashi T; Takahashi T; Azuma M; Okumura K; Yazaki Y; Yagita H; Hirai H
Protective and therapeutic immunity against leukemia induced by irradiated B7-1 (CD80)-transduced leukemic cells.
Human gene therapy 1997;8(11):1375-84.
1997: Maeda K; Sato T; Azuma M; Yagita H; Okumura K
Characterization of rat CD80 and CD86 by molecular cloning and mAb.
International immunology 1997;9(7):993-1000.
1997: Hattori K; Hirano T; Ushiyama C; Miyajima H; Yamakawa N; Ebata T; Wada Y; Ikeda S; Yoshino K; Tateno M; Oshimi K; Kayagaki N; Yagita H; Okumura K
A metalloproteinase inhibitor prevents lethal acute graft-versus-host disease in mice.
Blood 1997;90(2):542-8.
1997: Enomoto A; Kato K; Yagita H; Okumura K
Adoptive transfer of cytotoxic T lymphocytes induced by CD86-transfected tumor cells suppresses multi-organ metastases of C1300 neuroblastoma in mice.
Cancer immunology, immunotherapy : CII 1997;44(4):204-10.
1997: Kawahara T; Kasai S; Yagita H; Kato K; Sawa M; Nakajima A; Azuma M; Okumura K; Futagawa S; Mito M
Involvement of Fas and Fas ligand interaction in allogeneic hepatocyte rejection in the spleen.
Transplantation proceedings 1997;29(4):2187-8.
1997: Nozawa K; Kayagaki N; Tokano Y; Yagita H; Okumura K; Hasimoto H
Soluble Fas (APO-1, CD95) and soluble Fas ligand in rheumatic diseases.
Arthritis and rheumatism 1997;40(6):1126-9.
1997: Nakajima A; Watanabe N; Yoshino S; Yagita H; Okumura K; Azuma M
Requirement of CD28-CD86 co-stimulation in the interaction between antigen-primed T helper type 2 and B cells.
International immunology 1997;9(5):637-44.
1997: Nakano H; Shindo M; Yamada K; Yoshida M C; Santee S M; Ware C F; Jenkins N A; Gilbert D J; Yagita H; Copeland N C; Okumura K
Human TNF receptor-associated factor 5 (TRAF5): cDNA cloning, expression and assignment of the TRAF5 gene to chromosome 1q32.
Genomics 1997;42(1):26-32.
1997: Hirano N; Takahashi T; Takahashi T; Azuma M; Yazaki Y; Yagita H; Hirai H
Protective and therapeutic immunity against leukemia induced by irradiated B7-1 (CD80)-transduced leukemic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11 Suppl 3():577-81.
1997: Kato K; Okumura K; Yagita H
Immunoregulation by B7 and IL-12 gene transfer.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11 Suppl 3():572-6.
1997: Kayagaki N; Yamaguchi N; Nagao F; Matsuo S; Maeda H; Okumura K; Yagita H
Polymorphism of murine Fas ligand that affects the biological activity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3914-9.
1997: Sagara H; Matsuda H; Wada N; Yagita H; Fukuda T; Okumura K; Makino S; Ra C
A monoclonal antibody against very late activation antigen-4 inhibits eosinophil accumulation and late asthmatic response in a guinea pig model of asthma.
International archives of allergy and immunology 1997;112(3):287-94.
1997: Ohta Y; Gotoh M; Ohzato H; Nishihara M; Dono K; Umeshita K; Sakon M; Monden M; Yagita H; Okumura K; Kawashima H; Miyasaka M
Both donor and recipient adhesion molecules play a crucial role in inducing rejection of rat xenogeneic islets in mice.
Transplantation proceedings 1997;29(1-2):953.
1997: Seino K; Kayagaki N; Fukao K; Okumura K; Yagita H
Rejection of Fas ligand-expressing grafts.
Transplantation proceedings 1997;29(1-2):1092-3.
1997: Seino K; Kayagaki N; Okumura K; Yagita H
Antitumor effect of locally produced CD95 ligand.
Nature medicine 1997;3(2):165-70.
1997: Nakajima A; Hirose S; Yagita H; Okumura K
Roles of IL-4 and IL-12 in the development of lupus in NZB/W F1 mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(3):1466-72.
1997: Nakano H; Tamura T; Yoshimoto T; Yagita H; Miyasaka M; Butcher E C; Nariuchi H; Kakiuchi T; Matsuzawa A
Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes.
European journal of immunology 1997;27(1):215-21.
1997: Bashuda H; Seino K; Ra C; Yagita H; Okumura K
Lack of cognate help by CD4+ T cells and anergy of CD8+ T cells are the principal mechanisms for anti-leukocyte function-associated antigen-1/intercellular adhesion molecule-1-induced cardiac allograft tolerance.
Transplantation 1997;63(1):113-8.
1997: Takenaka H; Maruo S; Yamamoto N; Wysocka M; Ono S; Kobayashi M; Yagita H; Okumura K; Hamaoka T; Trinchieri G; Fujiwara H
Regulation of T cell-dependent and -independent IL-12 production by the three Th2-type cytokines IL-10, IL-6, and IL-4.
Journal of leukocyte biology 1997;61(1):80-7.
1997: Aizawa S; Nakano H; Ishida T; Horie R; Nagai M; Ito K; Yagita H; Okumura K; Inoue J; Watanabe T
Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation.
The Journal of biological chemistry 1997;272(4):2042-5.
1997: Maruo S; Oh-hora M; Ahn H J; Ono S; Wysocka M; Kaneko Y; Yagita H; Okumura K; Kikutani H; Kishimoto T; Kobayashi M; Hamaoka T; Trinchieri G; Fujiwara H
B cells regulate CD40 ligand-induced IL-12 production in antigen-presenting cells (APC) during T cell/APC interactions.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(1):120-6.
1996: Seko Y; Yagita H; Okumura K; Yazaki Y
Expression of vascular cell adhesion molecule-1 in murine hearts with acute myocarditis caused by coxsackievirus B3.
The Journal of pathology 1996;180(4):450-4.
1996: Saito K; Yagita H; Hashimoto H; Okumura K; Azuma M
Effect of CD80 and CD86 blockade and anti-interleukin-12 treatment on mouse acute graft-versus-host disease.
European journal of immunology 1996;26(12):3098-106.
1996: Kaneko Y; Hirose S; Abe M; Yagita H; Okumura K; Shirai T
CD40-mediated stimulation of B1 and B2 cells: implication in autoantibody production in murine lupus.
European journal of immunology 1996;26(12):3061-5.
1996: Seko Y; Enokawa Y; Tamatani T; Kannagi R; Yagita H; Okumura K; Yazaki Y
Expression of sialyl Lewis(X) in rat heart with ischaemia/reperfusion and reduction of myocardial reperfusion injury by a monoclonal antibody against sialyl Lewis(X)
The Journal of pathology 1996;180(3):305-10.
1996: Seko Y; Enokawa Y; Tamatani T; Kannagi R; Yagita H; Okumura K; Yazaki Y
Induction of sialyl Lewis(X) on the surface of cultured rat vascular endothelial cells and cardiac myocytes by hypoxia/reoxygenation in vitro.
The Journal of pathology 1996;180(3):300-4.
1996: Kaneko H; Saito K; Hashimoto H; Yagita H; Okumura K; Azuma M
Preferential elimination of CD28+ T cells in systemic lupus erythematosus (SLE) and the relation with activation-induced apoptosis.
Clinical and experimental immunology 1996;106(2):218-29.
1996: Sekine C; Yagita H; Kobata T; Hasunuma T; Nishioka K; Okumura K
Fas-mediated stimulation induces IL-8 secretion by rheumatoid arthritis synoviocytes independently of CPP32-mediated apoptosis.
Biochemical and biophysical research communications 1996;228(1):14-20.
1996: Yamataka A; Kato Y; Fujiwara T; Yagita H; Okumura K; Sunagawa M; Nozawa M; Miyano T
Impact of antibodies to leukocyte function-associated antigen-1 and intercellular adhesion molecule-1 on fetal bowel allo- and xenotransplantation in mice.
Transplantation proceedings 1996;28(5):2494-5.
1996: Moriyama H; Yokono K; Amano K; Nagata M; Hasegawa Y; Okamoto N; Tsukamoto K; Miki M; Yoneda R; Yagi N; Tominaga Y; Kikutani H; Hioki K; Okumura K; Yagita H; Kasuga M
Induction of tolerance in murine autoimmune diabetes by transient blockade of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 pathway.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(8):3737-43.
1996: Seko Y; Azuma M; Yagita H; Okumura K; Yazaki Y
Perforin-positive leukemic cell infiltration in the aortic tissue of a patient with T-cell prolymphocytic leukemia.
International angiology : a journal of the International Union of Angiology 1996;15(3):245-8.
1996: Seino K; Kayagaki N; Bashuda H; Okumura K; Yagita H
Contribution of Fas ligand to cardiac allograft rejection.
International immunology 1996;8(9):1347-54.
1996: Tokano Y; Miyake S; Kayagaki N; Nozawa K; Morimoto S; Azuma M; Yagita H; Takasaki Y; Okumura K; Hashimoto H
Soluble Fas molecule in the serum of patients with systemic lupus erythematosus.
Journal of clinical immunology 1996;16(5):261-5.
1996: Kato K; Shimozato O; Hoshi K; Wakimoto H; Hamada H; Yagita H; Okumura K
Local production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9085-9.
1996: Kashiwada M; Kaneko Y; Yagita H; Okumura K; Takemori T
Activation of mitogen-activated protein kinases via CD40 is distinct from that stimulated by surface IgM on B cells.
European journal of immunology 1996;26(7):1451-8.
1996: Bashuda H; Takazawa K; Tamatani T; Miyasaka M; Yagita H; Okumura K
Induction of persistent allograft tolerance in the rat by combined treatment with anti-leukocyte function-associated antigen-1 and anti-intercellular adhesion molecule-1 monoclonal antibodies, donor-specific transfusion, and FK506.
Transplantation 1996;62(1):117-22.
1996: Nuriya S; Yagita H; Okumura K; Azuma M
The differential role of CD86 and CD80 co-stimulatory molecules in the induction and the effector phases of contact hypersensitivity.
International immunology 1996;8(6):917-26.
1996: Nakano H; Oshima H; Chung W; Williams-Abbott L; Ware C F; Yagita H; Okumura K
TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor.
The Journal of biological chemistry 1996;271(25):14661-4.
1996: Takazawa K; Hosoda Y; Bashuda H; Seino K; Yagita H; Tamatani T; Miyasaka M; Okumura K
Synergistic effects of mycophenolate mofetil (MMF, RS-61443) and anti-LFA-1/ICAM-1 monoclonal antibodies on the prolongation of heart allograft survival in rats.
Transplantation proceedings 1996;28(3):1980-1.
1996: Higashiyama A; Watanabe H; Okumura K; Yagita H
Involvement of tumor necrosis factor alpha and very late activation antigen 4/vascular cell adhesion molecule 1 interaction in surgical-stress-enhanced experimental metastasis.
Cancer immunology, immunotherapy : CII 1996;42(4):231-6.
1996: Seko Y; Sato O; Takagi A; Tada Y; Matsuo H; Yagita H; Okumura K; Yazaki Y
Restricted usage of T-cell receptor Valpha-Vbeta genes in infiltrating cells in aortic tissue of patients with Takayasu's arteritis.
Circulation 1996;93(10):1788-90.
1996: Gotoh M; Ohzato H; Fukuzaki T; Ohta Y; Nishihara M; Hasuike Y; Umeshita K; Sakon M; Yagita H; Okumura K; Miyasaka M; Monden M
Role of adhesion molecules in islet allo- and xenograft rejection.
Transplantation proceedings 1996;28(2):617.
1996: Bashuda H; Seino K; Kano M; Sato K; Azuma M; Yagita H; Okumura K
Specific acceptance of cardiac allografts after treatment with antibodies to CD80 and CD86 in mice.
Transplantation proceedings 1996;28(2):1039-41.
1996: Seko Y; Enokawa Y; Nakao T; Yagita H; Okumura K; Yazaki Y
Reduction of rat myocardial ischaemia/reperfusion injury by a synthetic selectin oligopeptide.
The Journal of pathology 1996;178(3):335-42.
1996: Seko Y; Yoshifumi E; Yagita H; Okumura K; Yazaki Y
Restricted usage of T-cell receptor V alpha genes in infiltrating cells in murine hearts with acute myocarditis caused by coxsackie virus B3.
The Journal of pathology 1996;178(3):330-4.
1996: Yonezawa I; Kato K; Yagita H; Yamauchi Y; Okumura K
VLA-5-mediated interaction with fibronectin induces cytokine production by human chondrocytes.
Biochemical and biophysical research communications 1996;219(1):261-5.
1996: Kato Y; Yamataka A; Yagita H; Okumura K; Fujiwara T; Miyano T
Specific acceptance of fetal bowel allograft in mice after combined treatment with anti-intercellular adhesion molecule-1 and leukocyte function-associated antigen-1 antibodies.
Annals of surgery 1996;223(1):94-100.
1995: Hishii M; Nitta T; Ishida H; Ebato M; Kurosu A; Yagita H; Sato K; Okumura K
Human glioma-derived interleukin-10 inhibits antitumor immune responses in vitro.
Neurosurgery 1995;37(6):1160-6; discussion 1166-7.
1995: Kayagaki N; Kawasaki A; Ebata T; Ohmoto H; Ikeda S; Inoue S; Yoshino K; Okumura K; Yagita H
Metalloproteinase-mediated release of human Fas ligand.
The Journal of experimental medicine 1995;182(6):1777-83.
1995: Nakajima A; Azuma M; Kodera S; Nuriya S; Terashi A; Abe M; Hirose S; Shirai T; Yagita H; Okumura K
Preferential dependence of autoantibody production in murine lupus on CD86 costimulatory molecule.
European journal of immunology 1995;25(11):3060-9.
1995: Seko Y; Azuma M; Yagita H; Okumura K; Hirai H; Nagai R; Yazaki Y
Perforin-positive leukemic cell infiltration in the heart of a patient with T-cell prolymphocytic leukemia.
Internal medicine (Tokyo, Japan) 1995;34(8):782-4.
1995: Seko Y; Ishiyama S; Nishikawa T; Kasajima T; Hiroe M; Kagawa N; Osada K; Suzuki S; Yagita H; Okumura K
Restricted usage of T cell receptor V alpha-V beta genes in infiltrating cells in the hearts of patients with acute myocarditis and dilated cardiomyopathy.
The Journal of clinical investigation 1995;96(2):1035-41.
1995: Seino K; Azuma M; Bashuda H; Fukao K; Yagita H; Okumura K
CD86 (B70/B7-2) on endothelial cells co-stimulates allogeneic CD4+ T cells.
International immunology 1995;7(8):1331-7.
1995: Tanaka T; Ohtsuka Y; Yagita H; Shiratori Y; Omata M; Okumura K
Involvement of alpha 1 and alpha 4 integrins in gut mucosal injury of graft-versus-host disease.
International immunology 1995;7(8):1183-9.
1995: Kato Y; Yamataka A; Yagita H; Bashuda H; Okumura K; Miyano T
Prevention of fetal bowel allograft rejection by combined treatment with anti-ICAM-1 and anti-LFA-1 antibodies.
Journal of pediatric surgery 1995;30(7):1093-7.
1995: Takazawa K; Hosoda Y; Bashuda H; Yagita H; Okumura K; Kaneko Y
CAM--a novel immunosuppressive agent.
Transplantation 1995;59(12):1723-7.
1995: Noto K; Kato K; Okumura K; Yagita H
Identification and functional characterization of mouse CD29 with a mAb.
International immunology 1995;7(5):835-42.
1995: Nishihara M; Gotoh M; Fukuzaki T; Ohta Y; Monden M; Yagita H; Okumura K; Miyasaka M; Mori T
Potent immunosuppressive effect of anti-LFA-1 monoclonal antibody on islet allograft rejection.
Transplantation proceedings 1995;27(1):372.
1995: Ohta Y; Gotoh M; Fukuzaki T; Nishihara M; Yagita H; Okumura K; Miyasaka M; Monden M
Participation of donor adhesion molecules in islet xenograft rejection.
Transplantation proceedings 1995;27(1):256-7.
1995: Yasuda M; Hasunuma Y; Adachi H; Sekine C; Sakanishi T; Hashimoto H; Ra C; Yagita H; Okumura K
Expression and function of fibronectin binding integrins on rat mast cells.
International immunology 1995;7(2):251-8.
1995: Iwanuma Y; Kato K; Yagita H; Okumura K
Induction of tumor-specific cytotoxic T lymphocytes and natural killer cells by tumor cells transfected with the interleukin-2 gene.
Cancer immunology, immunotherapy : CII 1995;40(1):17-23.
1995: Ra C; Yasuda M; Sagara H; Yagita H; Okumura K
The role of adhesion molecules in triggering effector phase of immune responses.
Allergy proceedings : the official journal of regional and state allergy societies 1995;16(1):39-41.
1994: Ebato M; Nitta T; Yagita H; Sato K; Okumura K
Shared amino acid sequences in the ND beta N and N alpha regions of the T cell receptors of tumor-infiltrating lymphocytes within malignant glioma.
European journal of immunology 1994;24(12):2987-92.
1994: Ra C; Yasuda M; Yagita H; Okumura K
Fibronectin receptor integrins are involved in mast cell activation.
The Journal of allergy and clinical immunology 1994;94(3 Pt 2):625-8.
1994: Miyake S; Sakurai T; Okumura K; Yagita H
Identification of collagen and laminin receptor integrins on murine T lymphocytes.
European journal of immunology 1994;24(9):2000-5.
1994: Hasegawa Y; Yokono K; Taki T; Amano K; Tominaga Y; Yoneda R; Yagi N; Maeda S; Yagita H; Okumura K
Prevention of autoimmune insulin-dependent diabetes in non-obese diabetic mice by anti-LFA-1 and anti-ICAM-1 mAb.
International immunology 1994;6(6):831-8.
1994: Fukuzaki T; Gotoh M; Monden M; Ohta Y; Dono K; Kanai T; Yagita H; Okumura K; Miyasaka M; Mori T
Role of adhesion molecules in islet xenograft rejection.
Transplantation proceedings 1994;26(3):1113.
1994: Okahara H; Yagita H; Miyake K; Okumura K
Involvement of very late activation antigen 4 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) in tumor necrosis factor alpha enhancement of experimental metastasis.
Cancer research 1994;54(12):3233-6.
1994: Seko Y; Yagita H; Okumura K; Yazaki Y
T-cell receptor V beta gene expression in infiltrating cells in murine hearts with acute myocarditis caused by coxsackievirus B3.
Circulation 1994;89(5):2170-5.
1994: Hanabuchi S; Koyanagi M; Kawasaki A; Shinohara N; Matsuzawa A; Nishimura Y; Kobayashi Y; Yonehara S; Yagita H; Okumura K
Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):4930-4.
1994: Tsunetsugu-Yokota Y; Mizuochi T; Hashimoto H; Szikaradkiewicz A; Yagita H; Yano A; Takemori T
Analysis of function of a human antigen-presenting cell by xenogeneic interaction with mouse T cells.
Immunology letters 1994;40(1):73-7.
1994: Seko Y; Minota S; Kawasaki A; Shinkai Y; Maeda K; Yagita H; Okumura K; Sato O; Takagi A; Tada Y
Perforin-secreting killer cell infiltration and expression of a 65-kD heat-shock protein in aortic tissue of patients with Takayasu's arteritis.
The Journal of clinical investigation 1994;93(2):750-8.
1994: Gotoh M; Fukuzaki T; Monden M; Dono K; Kanai T; Yagita H; Okumura K; Mori T
A potential immunosuppressive effect of anti-lymphocyte function-associated antigen-1 monoclonal antibody on islet transplantation.
Transplantation 1994;57(1):123-6.
1993: Ebato M; Nitta T; Yagita H; Sato K; Okumura K
Skewed distribution of TCR V alpha 7-bearing T cells within tumor-infiltrating lymphocytes of HLA-A24(9)-positive patients with malignant glioma.
Immunology letters 1993;39(1):53-64.
1993: Uemura N; Ozawa K; Takahashi K; Tojo A; Tani K; Harigaya K; Suzu S; Motoyoshi K; Matsuda H; Yagita H
Binding of membrane-anchored macrophage colony-stimulating factor (M-CSF) to its receptor mediates specific adhesion between stromal cells and M-CSF receptor-bearing hematopoietic cells.
Blood 1993;82(9):2634-40.
1993: Yamataka T; Kobayashi H; Yagita H; Okumura K; Tamatani T; Miyasaka M
The effect of anti-ICAM-1 monoclonal antibody treatment on the transplantation of the small bowel in rats.
Journal of pediatric surgery 1993;28(11):1451-7.
1993: Azuma M; Ito D; Yagita H; Okumura K; Phillips J H; Lanier L L; Somoza C
B70 antigen is a second ligand for CTLA-4 and CD28.
Nature 1993;366(6450):76-9.
1993: Kobayashi H; Miyano T; Yamataka A; Yamataka T; Yagita H; Eto H; Ligo Y; Tansyo S; Kojima Y; Tamatani T
Prolongation of rat cardiac allograft survival by a monoclonal antibody: anti-rat intercellular adhesion molecule-1.
Cardiovascular surgery (London, England) 1993;1(5):577-82.
1993: Yamazaki T; Seko Y; Tamatani T; Miyasaka M; Yagita H; Okumura K; Nagai R; Yazaki Y
Expression of intercellular adhesion molecule-1 in rat heart with ischemia/reperfusion and limitation of infarct size by treatment with antibodies against cell adhesion molecules.
The American journal of pathology 1993;143(2):410-8.
1993: Kato K; Tamura N; Okumura K; Yagita H
Identification of the T cell surface signal-transducing glycoprotein sgp-60 as CD48, a counter-receptor for mouse CD2.
European journal of immunology 1993;23(6):1412-5.
1993: Seko Y; Shinkai Y; Kawasaki A; Yagita H; Okumura K; Yazaki Y
Evidence of perforin-mediated cardiac myocyte injury in acute murine myocarditis caused by Coxsackie virus B3.
The Journal of pathology 1993;170(1):53-8.
1993: Seko Y; Matsuda H; Kato K; Hashimoto Y; Yagita H; Okumura K; Yazaki Y
Expression of intercellular adhesion molecule-1 in murine hearts with acute myocarditis caused by coxsackievirus B3.
The Journal of clinical investigation 1993;91(4):1327-36.
1993: Miyake S; Yagita H; Maruyama T; Hashimoto H; Miyasaka N; Okumura K
Beta 1 integrin-mediated interaction with extracellular matrix proteins regulates cytokine gene expression in synovial fluid cells of rheumatoid arthritis patients.
The Journal of experimental medicine 1993;177(3):863-8.
1993: Gotoh M; Fukuzaki T; Dono K; Wada H; Kanai T; Monden M; Yagita H; Okumura K; Mori T
Induction of unresponsiveness to islet allograft by anti-LFA-1 monoclonal antibody treatment.
Transplantation proceedings 1993;25(1 Pt 2):973-4.
1992: Takeuchi Y; Tanaka T; Hamamura K; Sugimoto T; Miyasaka M; Yagita H; Okumura K
Expression and role of interleukin-2 receptor beta chain on CD4-CD8- T cell receptor alpha beta+ cells [corrected]
European journal of immunology 1992;22(11):2929-35.
1992: Kato K; Koyanagi M; Okada H; Takanashi T; Wong Y W; Williams A F; Okumura K; Yagita H
CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.
The Journal of experimental medicine 1992;176(5):1241-9.
1992: Minamizuka T; Eto H; Nakata M; Yagita H; Okumura K
Effect of immunization with anti-idiotypic antibody to melanoma antigen on lung metastasis in mice.
Nippon geka hokan. Archiv für japanische Chirurgie 1992;61(6):413-22.
1992: Seko Y; Yamazaki T; Shinkai Y; Yagita H; Okumura K; Naito S; Imataka K; Fujii J; Yazaki Y
Cellular and molecular bases for the immunopathology of the myocardial cell damage involved in acute viral myocarditis with special reference to dilated cardiomyopathy.
Japanese circulation journal 1992;56(10):1062-72.
1992: Nakata M; Kawasaki A; Azuma M; Tsuji K; Matsuda H; Shinkai Y; Yagita H; Okumura K
Expression of perforin and cytolytic potential of human peripheral blood lymphocyte subpopulations.
International immunology 1992;4(9):1049-54.
1992: Nitta T; Yagita H; Sato K; Okumura K
Expression of Fc gamma receptors on astroglial cell lines and their role in the central nervous system.
Neurosurgery 1992;31(1):83-7; discussion 87-8.
1992: Takahashi K; Nakata M; Tanaka T; Adachi H; Nakauchi H; Yagita H; Okumura K
CD4 and CD8 regulate interleukin 2 responses of T cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(12):5557-61.
1992: Kawasaki A; Shinkai Y; Yagita H; Okumura K
Expression of perforin in murine natural killer cells and cytotoxic T lymphocytes in vivo.
European journal of immunology 1992;22(5):1215-9.
1992: Ota Y; Kobata T; Seki M; Yagita H; Shimada S; Huang Y Y; Takagaki Y; Okumura K
Extrathymic origin of V gamma 1/V delta 6 T cells in the skin.
European journal of immunology 1992;22(2):595-8.
1992: Yagita H; Nakata M; Kawasaki A; Shinkai Y; Okumura K
Role of perforin in lymphocyte-mediated cytolysis.
Advances in immunology 1992;51():215-42.
1991: Seko Y; Shinkai Y; Kawasaki A; Yagita H; Okumura K; Takaku F; Yazaki Y
Expression of perforin in infiltrating cells in murine hearts with acute myocarditis caused by coxsackievirus B3.
Circulation 1991;84(2):788-95.
1991: Takahashi K; Nakamura T; Adachi H; Yagita H; Okumura K
Antigen-independent T cell activation mediated by a very late activation antigen-like extracellular matrix receptor.
European journal of immunology 1991;21(6):1559-62.
1991: Nitta T; Nakata M; Yagita H; Okumura K
Interleukin-2 activated T cells (T-LAK) express CD16 antigen and are triggered to target cell lysis by bispecific antibody.
Immunology letters 1991;28(1):31-7.
1991: Nitta T; Yagita H; Sato K; Okumura K
Surrogate receptor-mediated cellular cytotoxicity against malignant human glioma cells.
Neurosurgery 1991;28(3):394-9.
1991: Nakamura T; Takahashi K; Koyanagi M; Yagita H; Okumura K
Activation of a natural killer clone upon target cell binding via CD2.
European journal of immunology 1991;21(3):831-4.
1990: Nakata M; Smyth M J; Norihisa Y; Kawasaki A; Shinkai Y; Okumura K; Yagita H
Constitutive expression of pore-forming protein in peripheral blood gamma/delta T cells: implication for their cytotoxic role in vivo.
The Journal of experimental medicine 1990;172(6):1877-80.
1990: Takahashi K; Nakamura T; Koyanagi M; Kato K; Hashimoto Y; Yagita H; Okumura K
A murine very late activation antigen-like extracellular matrix receptor involved in CD2- and lymphocyte function-associated antigen-1-independent killer-target cell interaction.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(12):4371-9.
1990: Nakamura T; Takahashi K; Fukazawa T; Koyanagi M; Yokoyama A; Kato H; Yagita H; Okumura K
Relative contribution of CD2 and LFA-1 to murine T and natural killer cell functions.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(11):3628-34.
1990: Nitta T; Ishizawa A; Ito M; Sato K; Yagita H; Kumura K
[Induction of cytotoxicity from human lymphocytes coated with bispecific antibody against human glioma cells]
No shinkei geka. Neurological surgery 1990;18(11):1001-6.
1990: Sato T; Tamauchi H; Yagita H; Arat Y; Okumura K; Habu S
Dissociation of signal transduction via Thy-1 and CD3 antigens in murine T cells.
Immunology letters 1990;26(1):99-103.
1990: Nitta T; Yagita H; Okumura K; Sato K
[Analysis of receptor expression on astrocytic cells]
No to shinkei = Brain and nerve 1990;42(10):945-50.
1990: Kobata T; Yagita H; Matsuda H; Seki M; Ota Y; Katagiri M; Okumura K
Expression and function of a 90-kilodalton homodimeric molecule (10D1 antigen) on human thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(4):1053-8.
1990: Shirai T; Abe M; Yagita H; Okumura K; Morse H C; Davidson W F
The expanded populations of CD4-CD8- T cell receptor alpha/beta+ T cells associated with the lpr and gld mutations are CD2-.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(10):3756-61.
1990: Nitta T; Sato K; Yagita H; Okumura K; Ishii S
Preliminary trial of specific targeting therapy against malignant glioma.
Lancet 1990;335(8686):368-71.
1990: Kobata T; Yagita H; Matsuda H; Tansyo S; Yakura H; Katagiri M; Okumura K
A novel homodimeric molecule involved in human T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(3):830-5.
1990: Kawasaki A; Shinkai Y; Kuwana Y; Furuya A; Iigo Y; Hanai N; Itoh S; Yagita H; Okumura K
Perforin, a pore-forming protein detectable by monoclonal antibodies, is a functional marker for killer cells.
International immunology 1990;2(7):677-84.
1990: Kobata T; Shinkai Y; Iigo Y; Kawasaki A; Yagita H; Ito S; Shimada S; Katz S I; Okumura K
Thy-1-positive dendritic epidermal cells contain a killer protein perforin.
International immunology 1990;2(11):1113-6.
1989: Yagita H; Asakawa J; Tansyo S; Nakamura T; Habu S; Okumura K
Expression and function of CD2 during murine thymocyte ontogeny.
European journal of immunology 1989;19(12):2211-7.
1989: Ishikawa H; Shinkai Y; Yagita H; Yue C C; Henkart P A; Sawada S; Young H A; Reynolds C W; Okumura K
Molecular cloning of rat cytolysin.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(9):3069-73.
1989: Nitta T; Yagita H; Sato K; Okumura K
Involvement of CD56 (NKH-1/Leu-19 antigen) as an adhesion molecule in natural killer-target cell interaction.
The Journal of experimental medicine 1989;170(5):1757-61.
1989: Yagita H; Nakata M; Azuma A; Nitta T; Takeshita T; Sugamura K; Okumura K
Activation of peripheral blood T cells via the p75 interleukin 2 receptor.
The Journal of experimental medicine 1989;170(4):1445-50.
1989: Nitta T; Yagita H; Azuma T; Sato K; Okumura K
Bispecific F (ab')2 monomer prepared with anti-CD3 and anti-tumor monoclonal antibodies is most potent in induction of cytolysis of human T cells.
European journal of immunology 1989;19(8):1437-41.
1989: Yagita H; Nakamura T; Karasuyama H; Okumura K
Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(2):645-9.
1989: Shinkai Y; Yoshida M C; Maeda K; Kobata T; Maruyama K; Yodoi J; Yagita H; Okumura K
Molecular cloning and chromosomal assignment of a human perforin (PFP) gene.
Immunogenetics 1989;30(6):452-7.
1989: Yagita H; Nakamura T; Asakawa J; Matsuda H; Tansyo S; Iigo Y; Okumura K
CD2 expression in murine B cell lineage.
International immunology 1989;1(1):94-8.
1989: Tokano Y; Arai S; Hashimoto H; Hirose S; Yagita H; Nakauchi H; Kumagai Y; Arata Y; Okumura K
The distinct subgroup of patients with rheumatoid arthritis shown by Ig G3-reactive rheumatoid factor.
Autoimmunity 1989;5(1-2):107-14.
1988: Yamamoto K; Ono K; Nakahara K; Kitamura K; Yagita H; Okumura K
Characterization of a monoclonal antibody reacting with a neutral glycolipid that is associated with human T-cell leukemia virus type I infection and freshly isolated adult T-cell leukemia.
Cancer research 1988;48(11):3148-52.
1988: Yagita H; Okumura K; Nakauchi H
Molecular cloning of the murine homologue of CD2. Homology of the molecule to its human counterpart T11.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(4):1321-6.
1988: Hirano T; Miyajima H; Kitagawa H; Watanabe N; Azuma M; Taniguchi O; Hashimoto H; Hirose S; Yagita H; Furusawa S
Studies on murine IgE with monoclonal antibodies. I. Characterization of rat monoclonal anti-IgE antibodies and the use of these antibodies for determinations of serum IgE levels and for anaphylactic reactions.
International archives of allergy and applied immunology 1988;85(1):47-54.
1988: Tokano Y; Yagita H; Iida N; Hashimoto H; Okumura K; Hirose S
Relation between the level of IgG subclasses and infections in patients with systemic lupus erythematosus.
International archives of allergy and applied immunology 1988;87(1):55-8.
1987: Azuma M; Hirano T; Miyajima H; Watanabe N; Yagita H; Enomoto S; Furusawa S; Ovary Z; Kinashi T; Honjo T
Regulation of murine IgE production in SJA/9 and nude mice. Potentiation of IgE production by recombinant interleukin 4.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(8):2538-44.
1987: Nakauchi H; Osada H; Yagita H; Okumura K
Molecular evidence that SJL reticulum cell sarcomas are derived from pre-B cell. Clonal rearrangement of heavy chain but not of light chain immunoglobulin genes.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(8):2803-9.

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