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Hideo Yagita

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Kazuhiro Mochizuki; Qing Tong; Fang Xie; Hideo Yagita; Yajun Guo; Shan He; Koji Kato; Yongnian Liu; Shin Mineishi; Izumi Mochizuki; Yi Zhang
Delta-like ligand 4 identifies a previously uncharacterized population of inflammatory dendritic cells that plays important roles in eliciting allogeneic T cell responses in mice.
Waka Ishida; Tamaki Sumi; Osamu Taguchi; Masayuki Tsuda; Hideo Yagita; Ken Fukuda; Yosuke Harada; Atsuki Fukushima
Oral administration of Ag suppresses Ag-induced allergic conjunctivitis in mice: critical timing and dose of Ag.
Hong Zhou; Nhan L Tran; Michele B Weiss; Jeffrey A Winkles; Hideo Yagita; Kaushal Asrani; Sharron A N Brown; Emily Cheng; Suhendan Ekmekcioglu; Walter N Hittelman; John W Marks; Khalid A Mohamedali; Keeley K Phillips; Michael G Rosenblum
The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment.

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2013: Kazuhiro Mochizuki; Qing Tong; Fang Xie; Hideo Yagita; Yajun Guo; Shan He; Koji Kato; Yongnian Liu; Shin Mineishi; Izumi Mochizuki; Yi Zhang
Delta-like ligand 4 identifies a previously uncharacterized population of inflammatory dendritic cells that plays important roles in eliciting allogeneic T cell responses in mice.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(7):3772-82.
2013: Waka Ishida; Tamaki Sumi; Osamu Taguchi; Masayuki Tsuda; Hideo Yagita; Ken Fukuda; Yosuke Harada; Atsuki Fukushima
Oral administration of Ag suppresses Ag-induced allergic conjunctivitis in mice: critical timing and dose of Ag.
The British journal of ophthalmology 2013;97(4):492-7.
2013: Hong Zhou; Nhan L Tran; Michele B Weiss; Jeffrey A Winkles; Hideo Yagita; Kaushal Asrani; Sharron A N Brown; Emily Cheng; Suhendan Ekmekcioglu; Walter N Hittelman; John W Marks; Khalid A Mohamedali; Keeley K Phillips; Michael G Rosenblum
The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment.
The Journal of investigative dermatology 2013;133(4):1052-62.
2013: Muhammad Baghdadi; Hirotoshi Dosaka-Akita; Hiroko Nagao; Hideo Yagita; Hironori Yoshiyama; Hisaya Akiba; Masahisa Jinushi
Combined blockade of TIM-3 and TIM-4 augments cancer vaccine efficacy against established melanomas.
Cancer immunology, immunotherapy : CII 2013;62(4):629-37.
2013: Itaru Kuroda; Y Maeda; Atsushi Nemoto; T Tauchi; Hideo Yagita; Xiaochun Zhang; Koshi Akahane; Y Furukawa; Kumiko Goi; Kinuko Hirose; H Honna-Oshiro; Takeshi Inukai; Keiko Kagami; J Kikuchi; Kanji Sugita
BCR-ABL regulates death receptor expression for TNF-related apoptosis-inducing ligand (TRAIL) in Philadelphia chromosome-positive leukemia.
Oncogene 2013;32(13):1670-81.
2013: Nienke van der Werf; Hideo Yagita; Miyuki Azuma; Stephen A Redpath; Matthew D Taylor
Th2 cell-intrinsic hypo-responsiveness determines susceptibility to helminth infection.
PLoS pathogens 2013;9(3):e1003215.
2013: Deborah A Knight; Richard C Koya; Ming Li; Grant A McArthur; Stephen Mok; Shin Foong Ngiow; Tiffany Parmenter; Antoni Ribas; Ashley Cass; Thomas G Graeber; Nicole M Haynes; Kathryn Kinross; Hideo Yagita; Mark J Smyth
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
The Journal of clinical investigation 2013;123(3):1371-81.
2013: Catherine Gottschalk; Percy A Knolle; Richard A Kroczek; Vera Damuzzo; Janine Gotot; Isis Ludwig-Portugall; Kenneth M Murphy; Hideo Yagita; Christian Kurts
Batf3-dependent dendritic cells in the renal lymph node induce tolerance against circulating antigens.
Journal of the American Society of Nephrology : JASN 2013;24(4):543-9.
2013: Atsuko Nakatsuka; Daisuke Ogawa; Takahiro Terami; Sanae Teshigawara; Jun Wada; Hideo Yagita; Yasushi Matsuki; Kazutoshi Murakami; Jun Eguchi; Kazuyuki Hida; Kanji Higashio; Ryuji Hiramatsu; Kentaro Inoue; Izumi Iseda; Yoichiro Iwakura; Shigeru Kakuta; Motoko Kanzaki; Akihiro Katayama; Hirofumi Makino
Visceral adipose tissue-derived serine proteinase inhibitor inhibits apoptosis of endothelial cells as a ligand for the cell-surface GRP78/voltage-dependent anion channel complex.
Circulation research 2013;112(5):771-80.
2013: Melissa M Berrien-Elliott; Richard J DiPaolo; Philip D Greenberg; Stephanie R Jackson; Jennifer M Meyer; Thanh-Long M Nguyen; Craig J Rouskey; Hideo Yagita; Ryan M Teague
Durable adoptive immunotherapy for leukemia produced by manipulation of multiple regulatory pathways of CD8+ T-cell tolerance.
Cancer research 2013;73(2):605-16.
2013: Machiko Shimmura-Tomita; Hiroko Taniguchi; Mingcong Wang; Hideo Yagita; Hisaya Akiba; Junko Hori
Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts.
PloS one 2013;8(5):e63620.
2013: Atsuhiro Matsumoto; Yohei Mikami; Nobuhiro Nakamoto; Hidetsugu Saito; Toshiro Sato; Hideo Yagita; Po-Sung Chu; Hirotoshi Ebinuma; Takanori Kanai; Toshifumi Hibi
IL-22-Producing RORγt-Dependent Innate Lymphoid Cells Play a Novel Protective Role in Murine Acute Hepatitis.
PloS one 2013;8(4):e62853.
2013: Daqi Xu; Hideo Yagita; Han-Hsuan Fu; Joshua J Obar; Jang-June Park; Koji Tamada; Leo Lefrançois
A potential new pathway for PD-L1 costimulation of the CD8-T cell response to Listeria monocytogenes infection.
PloS one 2013;8(2):e56539.
2013: Lola Chabtini; Pranal J Dakle; Hisaya Akiba; Ibrahim Batal; Olaf Boenisch; Bechara Mfarrej; Marwan Mounayar; Nader Najafian; Brian D Smith; Hideo Yagita; Bing Zhu; Indira Guleria
TIM-3 regulates innate immune cells to induce fetomaternal tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(1):88-96.
2012: Xuehua Piao; Günther Schütz; Yasuo Uchiyama; Nico van Rooijen; Hideo Yagita; Hanno Ehlken; Mutsuko Hara; You-Wen He; Masato Koike; Sachiko Komazawa-Sakon; Hidetake Kurihara; Takashi Nishina; Masaki Ohmuraya; Ko Okumura; Jiang-Hu Piao; Hiroyasu Nakano
c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.
Science signaling 2012;5(255):ra93.
2012: Masafumi Nakayama; Alan Aderem; Keiichi Hiramatsu; Hiromi Kubagawa; Kenji Kurokawa; Bok Luel Lee; Kyohei Nakamura; Ko Okumura; Kazuhisa Sekimizu; Toshiyuki Takai; David M Underhill; Hideo Yagita; Kouetsu Ogasawara
Inhibitory receptor paired Ig-like receptor B is exploited by Staphylococcus aureus for virulence.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(12):5903-11.
2012: Amanda C Foks; Vanessa Frodermann; Johan Kuiper; Mariette Ter Borg; Ilze Bot; Saskia C A de Jager; Peter J Van Santbrink; Hideo Yagita; Gijs van Puijvelde
Interference of the CD30-CD30L pathway reduces atherosclerosis development.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(12):2862-8.
2012: Xiaochun Zhang; A Thomas Look; Hideo Yagita; Koshi Akahane; M Endo; Kumiko Goi; Kinuko Hirose; H Honda; H Honna-Oshiro; Toshiya Inaba; Takeshi Inukai; Keiko Kagami; M Kobayashi; Itaru Kuroda; H Kurosawa; K Nakamura; Shinpei Nakazawa; Kanji Sugita
Oncogenic fusion E2A-HLF sensitizes t(17;19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors.
Leukemia 2012;26(12):2483-93.
2012: Marie P Piechocki; Venuprasad Poojary; Gen Sheng Wu; Hideo Yagita; Judith Abrams; Stephen Ethier; Heather Gibson; Jennifer B Jacob; Richard F Jones; Wei-Zen Wei
Induction of proapoptotic antibodies to triple-negative breast cancer by vaccination with TRAIL death receptor DR5 DNA.
International journal of cancer. Journal international du cancer 2012;131(11):2562-72.
2012: Sayaka Tsugane; Hideo Yagita; Sho Takizawa; Motoki Ichikawa; Tomoki Kaneyama; Byung S Kim; Chang-Sung Koh
Therapeutic effects of anti-Delta1 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease.
Journal of neuroimmunology 2012;252(1-2):66-74.
2012: Atsuko Nakatsuka; Daisuke Ogawa; Takahiro Terami; Sanae Teshigawara; Jun Wada; Hideo Yagita; Yasushi Matsuki; Kazutoshi Murakami; Jun Eguchi; Kazuyuki Hida; Kanji Higashio; Ryuji Hiramatsu; Chikage Sato Horiguchi; Kentaro Inoue; Izumi Iseda; Yoichiro Iwakura; Shigeru Kakuta; Motoko Kanzaki; Akihiro Katayama; Hirofumi Makino
Vaspin is an adipokine ameliorating ER stress in obesity as a ligand for cell-surface GRP78/MTJ-1 complex.
Diabetes 2012;61(11):2823-32.
2012: H Hosseini; Zeyad Nasa; D Y Oh; Ban-Hock Toh; Hideo Yagita; Frank Alderuccio; S T Chan; X T Chen; J Chan
Non-myeloablative transplantation of bone marrow expressing self-antigen establishes peripheral tolerance and completely prevents autoimmunity in mice.
Gene therapy 2012;19(11):1075-84.
2012: Weiyi Peng; Laszlo G Radvanyi; Chunyu Xu; Hideo Yagita; Yan Yang; Chengwen Liu; Gregory Lizée; Yanyan Lou; Willem W Overwijk; Jieqing Chen; Patrick Hwu
PD-1 blockade enhances T-cell migration to tumors by elevating IFN-γ inducible chemokines.
Cancer research 2012;72(20):5209-18.
2012: Jiang-Hu Piao; Hideo Yagita; Ko Okumura; Hiroyasu Nakano
Aberrant accumulation of interleukin-10-secreting neutrophils in TRAF2-deficient mice.
Immunology and cell biology 2012;90(9):881-8.
2012: Zhi-Chun Ding; Lei Huang; Andrew L Mellor; David H Munn; Hideo Yagita; Bruce R Blazar; Gang Zhou
Polyfunctional CD4⁺ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy.
Blood 2012;120(11):2229-39.
2012: Christina K Baumgartner; Hideo Yagita; Laurent P Malherbe
A TCR affinity threshold regulates memory CD4 T cell differentiation following vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(5):2309-17.
2012: Shigeki Chiba; John D Colgan; Hirotoshi Dosaka-Akita; Yoichiro Fujioka; Jacob V Gorman; Mitsuomi Hirashima; Ichiro Kinoshita; Yusuke Ohba; Akinori Takaoka; Toshimitsu Uede; Hideo Yagita; Hironori Yoshiyama; Hisaya Akiba; Muhammad Baghdadi; Masahisa Jinushi
Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1.
Nature immunology 2012;13(9):832-42.
2012: Satoshi Nunomura; Manabu Ozawa; Chisei Ra; Kiyoshi Ando; Sonoko Habu; Toshio Itoh; Yoshie Kametani; Azumi Kono; Masanobu Satake; Shin Shimada; Hiroshi Suemizu; Ryuji Suzuki; Kenzaburo Tani; Hideo Yagita; Yuko Yamada; Mino Yoshioka; Erika Sasaki
Double expression of CD34 and CD117 on bone marrow progenitors is a hallmark of the development of functional mast cell of Callithrix jacchus (common marmoset).
International immunology 2012;24(9):593-603.
2012: Fumihiko Makino; Ko Okumura; Kazuhisa Takahashi; Hideo Yagita; Yoshiyuki Abe; Norihiro Harada; Jun Ito; Fumitaka Kamachi; Hisaya Akiba
Blockade of CD70-CD27 interaction inhibits induction of allergic lung inflammation in mice.
American journal of respiratory cell and molecular biology 2012;47(3):298-305.
2012: Anurag Gupta; Alexander Knuth; Alexandro Landshammer; Sabine Muth; Hans Christian Probst; Martin Pruschy; Reto Schwendener; Van Vuong; Hideo Yagita; Maries van den Broek
Radiotherapy promotes tumor-specific effector CD8+ T cells via dendritic cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(2):558-66.
2012: Daiju Fukuda; Cem Z Gorgun; Gökhan S Hotamisligil; Victor Kotelianski; Tatiana I Novobrantseva; Filip K Swirski; Ralph Weissleder; Hideo Yagita; Hiroyuki Yamazaki; Elena Aikawa; Jon C Aster; Aleksey Chudnovskiy; Kevin Croce; Masanori Aikawa
Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(27):E1868-77.
2012: Inge Verbrugge; Alison West; Hideo Yagita; Hélène Duret; Mara Galli; Jim Hagekyriakou; Ricky W Johnstone; Nicole M McLaughlin; Leslie L Sharp; Mark J Smyth; Nicole M Haynes
Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies.
Cancer research 2012;72(13):3163-74.
2012: Janine Gotot; Catherine Gottschalk; Percy A Knolle; Christian Kurts; Sonny Leopold; Hideo Yagita; Isis Ludwig-Portugall
Regulatory T cells use programmed death 1 ligands to directly suppress autoreactive B cells in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(26):10468-73.
2012: Magali Terme; Evelyn Ullrich; Sophie Viaud; Hideo Yagita; Laetitia Aymeric; Nathalie Chaput; Lieping Chen; Jerome Coudert; Mariapia Degli-Esposti; Mélanie Desbois; François Ghiringhelli; Gilles Kaplanski; Masashi Kato; Guido Kroemer; Salaheddine Mécheri; Kathrin Meinhardt; Armelle Prévost-Blondel; Bernard Ryffel; Joachim L Schultze; Eric Tartour; Laurence Zitvogel
Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells.
Cancer research 2012;72(11):2757-67.
2012: Nicholas Stephen Rennie Sanderson; Mark Swerdlow; Hideo Yagita; Mariana Puntel; Niyati S Bondale; Maria G Castro; Ahmed Ibrahim; Niloufar Iranmanesh; Kurt M Kroeger; Pedro R Lowenstein
Cytotoxic immunological synapses do not restrict the action of interferon-γ to antigenic target cells.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(20):7835-40.
2012: Yuji Nozaki; Sarah L Snelgrove; Hideo Yagita; Hisaya Akiba; Stephen R Holdsworth; David J Nikolic-Paterson; A Richard Kitching
Endogenous Tim-1 (Kim-1) promotes T-cell responses and cell-mediated injury in experimental crescentic glomerulonephritis.
Kidney international 2012;81(9):844-55.
2012: Wassim Elyaman; Ribal Bassil; Elizabeth M Bradshaw; Youmna Lahoud; William Orent; Freddy Radtke; Hideo Yagita; Bing Zhu; Samia J Khoury
Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells.
Immunity 2012;36(4):623-34.
2012: Han Dong; Nathan A Franklin; Martin J Glennie; Drew J Roberts; Hideo Yagita; Timothy N J Bullock
CD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(8):3829-38.
2012: Shigeru Yoshida; Hitoshi Chiba; Kazunori Fugo; Mizuho Kajikawa; Jun Koizumi; Katsumi Maenaka; Rania Hassan Mohamed; Noriyuki Otsuka; Minami Tanaka; Hideo Yagita; Masanori Kasahara
Involvement of an NKG2D ligand H60c in epidermal dendritic T cell-mediated wound repair.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(8):3972-9.
2012: Nadir Kadri; Eva Korpos; Agnes Lehuen; Linda Löfbom; Lydia Sorokin; Hideo Yagita; Christian Boitard; Claire Briet; Shashank Gupta; Dan Holmberg; Susanna L Cardell
CD4(+) type II NKT cells mediate ICOS and programmed death-1-dependent regulation of type 1 diabetes.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(7):3138-49.
2012: Hisako Kayama; Atsuko Kubo; Ji Su Ma; Masaaki Murakami; Taku Okazaki; Ryu Okumura; Yukihisa Sawa; Masaru Ishii; Seong Gyu Jeon; Yoshiyasu Ueda; Hideo Yagita; Masahiro Yamamoto; Kiyoshi Takeda
Intestinal CX3C chemokine receptor 1(high) (CX3CR1(high)) myeloid cells prevent T-cell-dependent colitis.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(13):5010-5.
2012: Akemi Koyanagi; Chiyoko Sekine; Hideo Yagita
Expression of Notch receptors and ligands on immature and mature T cells.
Biochemical and biophysical research communications 2012;418(4):799-805.
2012: Patcharee Ritprajak; Hideo Yagita; Hisaya Akiba; Masaaki Hashiguchi; Ko Okumura; Miyuki Azuma
Antibodies against B7-DC with differential binding properties exert opposite effects.
Hybridoma (2005) 2012;31(1):40-7.
2012: Estelle Hess; Frédéric Lézot; Hideo Yagita; Ariane Berdal; Mattéo R Bosisio; S Lori Bridal; Sylvestre Chea; Yongwon Choi; Marion Decossas; Vincent Duheron; Rachel Golub; Christopher G Mueller
RANKL induces organized lymph node growth by stromal cell proliferation.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(3):1245-54.
2012: Motoko Kanzaki; Akihiro Katayama; Hisaya Akiba; Jun Eguchi; Kentaro Inoue; Kazutoshi Murakami; Atsuko Nakatsuka; Koichi Sugiyama; Takahiro Terami; Sanae Teshigawara; Jun Wada; Hideo Yagita; Hirofumi Makino
Galectin-9 and T cell immunoglobulin mucin-3 pathway is a therapeutic target for type 1 diabetes.
Endocrinology 2012;153(2):612-20.
2012: Keiko Danzaki; Masahiro Ikesue; Koyu Ito; Yoichiro Iwakura; Masashi Kanayama; Daisuke Kurotaki; Yutaka Matsui; Junko Morimoto; Daichi Ohta; Hiroyuki Tsutsui; Hideo Yagita; Toshimitsu Uede
Interleukin-17A deficiency accelerates unstable atherosclerotic plaque formation in apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(2):273-80.
2012: Waka Ishida; Mina Kajisako; Hironori Matsuda; Tamaki Sumi; Hideo Yagita; Ken Fukuda; Atsuki Fukushima
B and T lymphocyte attenuator regulates the development of antigen-induced experimental conjunctivitis.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2012;250(2):289-95.
2012: Leonor Remédio; Hideo Yagita; António Duarte; Diana Martins; Ana Bastos-Carvalho; Francisco Caiado; Tânia Carvalho; Sergio Dias
Context- and cell-dependent effects of Delta-like 4 targeting in the bone marrow microenvironment.
PloS one 2012;7(12):e52450.
2012: Sonia Feau; Zacarias Garcia; Ramon Arens; Jannie Borst; Hideo Yagita; Stephen P Schoenberger
The CD4⁺ T-cell help signal is transmitted from APC to CD8⁺ T-cells via CD27-CD70 interactions.
Nature communications 2012;3():948.
2012: Chiyoko Sekine; Shigeru Chiba; Katsuto Hozumi; Noriko Koyama; Akemi Koyanagi; Hideo Yagita
Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes.
Arthritis research & therapy 2012;14(2):R45.
2011: Hina Shariff; Hideo Yagita; Nizam Mamode; Lucy Meader; Marco Coccia; Nicola Gardner; Roseanna E Greenlaw; Stipo Jurcevic
Role of the Fc region in CD70-specific antibody effects on cardiac transplant survival.
Transplantation 2011;92(11):1194-201.
2011: Leonardo V Riella; Takuya Ueno; Hideo Yagita; Ribal Bassil; Ibrahim Batal; Anil Chandraker; Sacha A De Serres; Wassim Elyaman; José O Medina Pestana; Nader Najafian
Blockade of Notch ligand δ1 promotes allograft survival by inhibiting alloreactive Th1 cells and cytotoxic T cell generation.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(9):4629-38.
2011: Francesca D'Addio; La Tonya Adams; Miyuki Azuma; Lola Chabtini; Bechara G Mfarrej; Leonardo V Riella; Mohamed H Sayegh; Hideo Yagita; Melissa Yeung; Indira Guleria
The link between the PDL1 costimulatory pathway and Th17 in fetomaternal tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(9):4530-41.
2011: Yuji Nozaki; Hideo Yagita; Hisaya Akiba; Stephen R Holdsworth; David J Nikolic-Paterson; A Richard Kitching
Tim-1 promotes cisplatin nephrotoxicity.
American journal of physiology. Renal physiology 2011;301(5):F1098-104.
2011: Waka Ishida; Noriko Koyama; Akemi Koyanagi; Shuji Sakamoto; Hideo Yagita; Ken Fukuda; Atsuki Fukushima
Regulation of experimental autoimmune uveoretinitis by anti-delta-like ligand 4 monoclonal antibody.
Investigative ophthalmology & visual science 2011;52(11):8224-30.
2011: Qing Ding; Nader Najafian; Hisaya Akiba; Geoffrey Camirand; Geetha Chalasani; Mohamed H Sayegh; Hideo Yagita; Melissa Yeung; Qiang Zeng; David M Rothstein
Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice.
The Journal of clinical investigation 2011;121(9):3645-56.
2011: Ribal Bassil; Wassim Elyaman; Youmna Lahoud; Leonardo V Riella; Hideo Yagita; Bing Zhu; Samia J Khoury
Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(5):2322-8.
2011: Jun Ito; Fumihiko Makino; Osamu Nagashima; Ko Okumura; Hisaya Akiba; Ryo Atsuta; Delbert R Dorscheid; Norihiro Harada; Yoshihiko Usui; Hideo Yagita; Kazuhisa Takahashi
Wound-induced TGF-β1 and TGF-β2 enhance airway epithelial repair via HB-EGF and TGF-α.
Biochemical and biophysical research communications 2011;412(1):109-14.
2011: Magali Terme; Evelyn Ullrich; Laetitia Aymeric; Kathrin Meinhardt; Mélanie Desbois; Nicolas Delahaye; Sophie Viaud; Bernard Ryffel; Hideo Yagita; Gilles Kaplanski; Armelle Prévost-Blondel; Masashi Kato; Joachim L Schultze; Eric Tartour; Guido Kroemer; Nathalie Chaput; Laurence Zitvogel
IL-18 induces PD-1-dependent immunosuppression in cancer.
Cancer research 2011;71(16):5393-9.
2011: Jun Yang; Xueli Yuan; Xiaozhi Zhao; Arlene H Sharpe; Vijay Vanguri; Toshihiko Watanabe; Hideo Yagita; Miyuki Azuma; Bruce R Blazar; Anil Chandraker; Susanne Chock; Gordon J Freeman; Tao Liu; Alison M Paterson; Leonardo V Riella; Scott J Rodig; Mohamed H Sayegh
The novel costimulatory programmed death ligand 1/B7.1 pathway is functional in inhibiting alloimmune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(3):1113-9.
2011: Sophie R Sierro; Hideo Yagita; Alena Donda; Philippe Guillaume; Frédéric Levy; Rachel Perret; Pedro Romero
Combination of lentivector immunization and low-dose chemotherapy or PD-1/PD-L1 blocking primes self-reactive T cells and induces anti-tumor immunity.
European journal of immunology 2011;41(8):2217-28.
2011: Govindarajan Thangavelu; Hideo Yagita; Louis Boon; Kenneth M Murphy; Colin C Anderson
The role of co-inhibitory signals in spontaneous tolerance of weakly mismatched transplants.
Immunobiology 2011;216(8):918-24.
2011: Masahisa Jinushi; Ichiro Kinoshita; Kenkichi Masutomi; Shigeki Chiba; Hirotoshi Dosaka-Akita; Akinori Takaoka; Hideo Yagita; Hironori Yoshiyama; Hideaki Tahara
Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(30):12425-30.
2011: Nagisa Sakurai; Leila Su; Mai Suzuki; Julie Teruya-Feldstein; Shinobu Tsuzuki; Lisheng Wang; John C Williams; Hideo Yagita; Ravi Bhatia; Stefano Casola; Shigeru Chiba; Yuichi Ishikawa; Sung-Uk Lee; Min Li; Manami Maeda; Toshiki I Saito; Takahiro Maeda
The LRF transcription factor regulates mature B cell development and the germinal center response in mice.
The Journal of clinical investigation 2011;121(7):2583-98.
2011: Hong Zhou; Hideo Yagita; Lawrence H Cheung; Walter N Hittelman; John W Marks; Michael G Rosenblum; Jeffrey A Winkles
Development and characterization of a potent immunoconjugate targeting the Fn14 receptor on solid tumor cells.
Molecular cancer therapeutics 2011;10(7):1276-88.
2011: Pablo Penaloza-MacMaster; Hideo Yagita; Ata Ur Rasheed; Bruce R Blazar; Smita S Iyer; Rafi Ahmed
Opposing effects of CD70 costimulation during acute and chronic lymphocytic choriomeningitis virus infection of mice.
Journal of virology 2011;85(13):6168-74.
2011: Xiaochun Zhang; Tetsuzo Tauchi; Hideo Yagita; Koshi Akahane; Kumiko Goi; Kinuko Hirose; Hiroko Honna; Takeshi Inukai; Keiko Kagami; Itaru Kuroda; Kanji Sugita
Endoplasmic reticulum stress inducers, but not imatinib, sensitize Philadelphia chromosome-positive leukemia cells to TRAIL-mediated apoptosis.
Leukemia research 2011;35(7):940-9.
2011: Koichiro Matsumoto; Takafumi Matsumoto; Yuko Matsunaga; Atsushi Moriwaki; Yoichi Nakanishi; Osamu Takeuchi; Hiroko Tsutsui; Hideo Yagita; Shizuo Akira; Yukari Asai; Miyuki Azuma; Miyuki Eguchi-Tsuda; Satoru Fukuyama; Keiko Kan-O; Taro Kawai; Hiromasa Inoue
Essential role of B7-H1 in double-stranded RNA-induced augmentation of an asthma phenotype in mice.
American journal of respiratory cell and molecular biology 2011;45(1):31-9.
2011: Amelia J Brennan; Kylie A Browne; Jenny Chia; Annette Ciccone; Sarah Ellis; Jamie A Lopez; Olivia Susanto; Joseph A Trapani; Sandra Verschoor; James C Whisstock; Hideo Yagita; Ilia Voskoboinik
Protection from endogenous perforin: glycans and the C terminus regulate exocytic trafficking in cytotoxic lymphocytes.
Immunity 2011;34(6):879-92.
2011: Tatsuyoshi Kawamura; Youichi Ogawa; Osamu Shimozato; Takashi Ando; Atsuhito Nakao; Tetsuji Kobata; Ko Okumura; Hideo Yagita; Shinji Shimada
CD70 is selectively expressed on Th1 but not on Th2 cells and is required for Th1-type immune responses.
The Journal of investigative dermatology 2011;131(6):1252-61.
2011: Ben P Martin; Ailsa J Frew; Michael Bots; Stephen Fox; Fenella Long; Kazuyoshi Takeda; Hideo Yagita; Peter Atadja; Mark J Smyth; Ricky Johnstone
Antitumor activities and on-target toxicities mediated by a TRAIL receptor agonist following cotreatment with panobinostat.
International journal of cancer. Journal international du cancer 2011;128(11):2735-47.
2011: Emily Hams; Mark J McCarron; Sylvie Amu; Hideo Yagita; Miyuki Azuma; Lieping Chen; Padraic G Fallon
Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(10):5648-55.
2011: Shin Foong Ngiow; Bianca von Scheidt; Hisaya Akiba; Hideo Yagita; Michele W L Teng; Mark J Smyth
Anti-TIM3 antibody promotes T cell IFN-γ-mediated antitumor immunity and suppresses established tumors.
Cancer research 2011;71(10):3540-51.
2011: Rebecca A Sweet; Michelle L Ols; Jaime L Cullen; Ashley Viehmann Milam; Hideo Yagita; Mark J Shlomchik
Facultative role for T cells in extrafollicular Toll-like receptor-dependent autoreactive B-cell responses in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(19):7932-7.
2011: Chieko Ishifune; Yoichi Maekawa; Jun Nishida; Akiko Kitamura; Kenji Tanigaki; Hideo Yagita; Koji Yasutomo
Notch signaling regulates the development of a novel type of Thy1-expressing dendritic cell in the thymus.
European journal of immunology 2011;41(5):1309-20.
2011: Makoto Takenouchi; Sachie Hirai; Naoya Sakuragi; Hideo Yagita; Hirofumi Hamada; Kazunori Kato
Epigenetic modulation enhances the therapeutic effect of anti-IL-13R(alpha)2 antibody in human mesothelioma xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(9):2819-29.
2011: Waka Ishida; Ken Fukuda; Tamaki Sumi; Nobuyuki Ebihara; Mina Kajisako; Hironori Matsuda; Hideo Yagita; Atsuki Fukushima
Adjuvants determine the contribution of basophils to antigen sensitization in vivo.
Immunology letters 2011;136(1):49-54.
2011: John Stagg; Sherene Loi; Upulie Divisekera; Shin Foong Ngiow; Helene Duret; Hideo Yagita; Michele W L Teng; Mark J Smyth
Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(17):7142-7.
2011: Nobuhiro Nakano; Chiharu Nishiyama; Hideo Yagita; Akemi Koyanagi; Hideoki Ogawa; Ko Okumura
Notch1-mediated signaling induces MHC class II expression through activation of class II transactivator promoter III in mast cells.
The Journal of biological chemistry 2011;286(14):12042-8.
2011: Stephanie K Watkins; Ziqiang Zhu; Elena Riboldi; Kim A Shafer-Weaver; Katherine E R Stagliano; Martha M Sklavos; Stefan Ambs; Hideo Yagita; Arthur A Hurwitz
FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer.
The Journal of clinical investigation 2011;121(4):1361-72.
2011: Gang Jee Ko; Hye Ryoun Jang; Yanfei Huang; Karl L Womer; Manchang Liu; Elizabeth Higbee; Zuoxiang Xiao; Hideo Yagita; Lorraine C Racusen; Abdel Rahim A Hamad; Hamid Rabb
Blocking Fas ligand on leukocytes attenuates kidney ischemia-reperfusion injury.
Journal of the American Society of Nephrology : JASN 2011;22(4):732-42.
2011: Vincent Duheron; Estelle Hess; Monique Duval; Marion Decossas; Beatriz Castaneda; Jennifer E Klöpper; Leonela Amoasii; Jean-Baptiste Barbaroux; Ifor Williams; Hideo Yagita; Josef Penninger; Yongwon Choi; Frédéric Lézot; Richard Groves; Ralf Paus; Christopher G Mueller
Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(13):5342-7.
2011: Juan Ma; Yoshihiko Usui; Kazuyoshi Takeda; Norihiro Harada; Hideo Yagita; Ko Okumura; Hisaya Akiba
TIM-1 signaling in B cells regulates antibody production.
Biochemical and biophysical research communications 2011;406(2):223-8.
2011: Song Rong; Joon-Keun Park; Torsten Kirsch; Hideo Yagita; Hisaya Akiba; Olaf Boenisch; Hermann Haller; Nader Najafian; Antje Habicht
The TIM-1:TIM-4 pathway enhances renal ischemia-reperfusion injury.
Journal of the American Society of Nephrology : JASN 2011;22(3):484-95.
2011: Mamiko Sakata-Yanagimoto; Toru Sakai; Yasuyuki Miyake; Toshiki I Saito; Haruhiko Maruyama; Yasuyuki Morishita; Etsuko Nakagami-Yamaguchi; Keiki Kumano; Hideo Yagita; Masashi Fukayama; Seishi Ogawa; Mineo Kurokawa; Koji Yasutomo; Shigeru Chiba
Notch2 signaling is required for proper mast cell distribution and mucosal immunity in the intestine.
Blood 2011;117(1):128-34.
2011: Sayuri Yamazaki; Kohei Okada; Akira Maruyama; Misako Matsumoto; Hideo Yagita; Tsukasa Seya
TLR2-dependent induction of IL-10 and Foxp3+ CD25+ CD4+ regulatory T cells prevents effective anti-tumor immunity induced by Pam2 lipopeptides in vivo.
PloS one 2011;6(4):e18833.
2011: Carla Real; Leonor Remédio; Francisco Caiado; Cátia Igreja; Cristina Borges; Alexandre Trindade; Perpétua Pinto-do-Ó; Hideo Yagita; Antonio Duarte; Sérgio Dias
Bone marrow-derived endothelial progenitors expressing Delta-like 4 (Dll4) regulate tumor angiogenesis.
PloS one 2011;6(4):e18323.
2011: Toshio Kawamoto; Yuko Kojima; Juan Ma; Fumihiko Makino; Shinji Morimoto; Ko Okumura; Yoshinari Takasaki; Yoshihiko Usui; Hideo Yagita; Yoshiyuki Abe; Jun Ito; Hisaya Akiba
Anti-T cell immunoglobulin and mucin domain-2 monoclonal antibody exacerbates collagen-induced arthritis by stimulating B cells.
Arthritis research & therapy 2011;13(2):R47.
2011: Shahram Salek-Ardakani; Rachel Flynn; Ramon Arens; Hideo Yagita; Geoffrey L Smith; Jannie Borst; Stephen P Schoenberger; Michael Croft
The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice.
The Journal of clinical investigation 2011;121(1):296-307.
2011: Kiyohiko Hotta; Masayuki Sho; Ichiro Yamato; Keiji Shimada; Hiroshi Harada; Takahiro Akahori; Shinji Nakamura; Noboru Konishi; Hideo Yagita; Katsuya Nonomura; Yoshiyuki Nakajima
Direct targeting of fibroblast growth factor-inducible 14 protein protects against renal ischemia reperfusion injury.
Kidney international 2011;79(2):179-88.
2010: Yoichiro Uchida; Bibo Ke; Maria Cecilia S Freitas; Hideo Yagita; Hisaya Akiba; Ronald W Busuttil; Nader Najafian; Jerzy W Kupiec-Weglinski
T-cell immunoglobulin mucin-3 determines severity of liver ischemia/reperfusion injury in mice in a TLR4-dependent manner.
Gastroenterology 2010;139(6):2195-206.
2010: Olaf Boenisch; Francesca D'Addio; Toshihiko Watanabe; Wassim Elyaman; Ciara N Magee; Melissa Y Yeung; Robert F Padera; Scott J Rodig; Takaya Murayama; Katsunori Tanaka; Xueli Yuan; Takuya Ueno; Anke Jurisch; Bechara Mfarrej; Hisaya Akiba; Hideo Yagita; Nader Najafian
TIM-3: a novel regulatory molecule of alloimmune activation.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(10):5806-19.
2010: Qifeng Zhou; Haiyan Xiao; Yanjun Liu; Yibing Peng; Yuan Hong; Hideo Yagita; Phillip R Chandler; David H Munn; Andrew L Mellor; Ning Fu; Yukai He
Blockade of programmed death-1 pathway rescues the effector function of tumor-infiltrating T cells and enhances the antitumor efficacy of lentivector immunization.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(9):5082-92.
2010: Drew J Roberts; Nathan A Franklin; Lara M Kingeter; Hideo Yagita; Alison L Tutt; Martin J Glennie; Timothy N J Bullock
Control of established melanoma by CD27 stimulation is associated with enhanced effector function and persistence, and reduced PD-1 expression of tumor infiltrating CD8(+) T cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(8):769-79.
2010: Akihiko Murata; Kazuki Okuyama; Seiji Sakano; Masahiro Kajiki; Tomohisa Hirata; Hideo Yagita; Juan Carlos Zúñiga-Pflücker; Kensuke Miyake; Sachiko Akashi-Takamura; Sawako Moriwaki; Shumpei Niida; Miya Yoshino; Shin-Ichi Hayashi
A Notch ligand, Delta-like 1 functions as an adhesion molecule for mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(7):3905-12.
2010: Koshi Akahane; Takeshi Inukai; Xiaochun Zhang; Kinuko Hirose; Itaru Kuroda; Kumiko Goi; Hiroko Honna; Keiko Kagami; Shinpei Nakazawa; Kazushi Endo; Takeo Kubota; Hideo Yagita; Toshiko Koyama-Okazaki; Kanji Sugita
Resistance of T-cell acute lymphoblastic leukemia to tumor necrosis factor--related apoptosis-inducing ligand-mediated apoptosis.
Experimental hematology 2010;38(10):885-95.
2010: Spela Konjar; Vivien R Sutton; Sabine Hoves; Urska Repnik; Hideo Yagita; Thomas Reinheckel; Christoph Peters; Vito Turk; Boris Turk; Joseph A Trapani; Natasa Kopitar-Jerala
Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L.
Immunology 2010;131(2):257-67.
2010: Halvor S McGee; Hideo Yagita; Zhifei Shao; Devendra K Agrawal
Programmed Death-1 antibody blocks therapeutic effects of T-regulatory cells in cockroach antigen-induced allergic asthma.
American journal of respiratory cell and molecular biology 2010;43(4):432-42.
2010: Tomohiro Fukaya; Hideaki Takagi; Yumiko Sato; Katsuaki Sato; Kawori Eizumi; Honami Taya; Tae Kwang Shin; Lieping Chen; Chen Dong; Miyuki Azuma; Hideo Yagita; Bernard Malissen; Katsuaki Sato
Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4+Foxp3+ regulatory T cells in the establishment of oral tolerance.
Blood 2010;116(13):2266-76.
2010: Tadashi Yokosuka; Wakana Kobayashi; Masako Takamatsu; Kumiko Sakata-Sogawa; Hu Zeng; Akiko Hashimoto-Tane; Hideo Yagita; Makio Tokunaga; Takashi Saito
Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation.
Immunity 2010;33(3):326-39.
2010: Daisuke Muraoka; Takuma Kato; Linan Wang; Yuka Maeda; Takuro Noguchi; Naozumi Harada; Kazuyoshi Takeda; Hideo Yagita; Philippe Guillaume; Immanuel Luescher; Lloyd J Old; Hiroshi Shiku; Hiroyoshi Nishikawa
Peptide vaccine induces enhanced tumor growth associated with apoptosis induction in CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(6):3768-76.
2010: Naoya Takeichi; Satoshi Yanagisawa; Tomoki Kaneyama; Hideo Yagita; Young-Hee Jin; Byung S Kim; Chang-Sung Koh
Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease.
International immunology 2010;22(9):729-38.
2010: Natsumi Abe; Katsuto Hozumi; Ken-ichi Hirano; Hideo Yagita; Sonoko Habu
Notch ligands transduce different magnitudes of signaling critical for determination of T-cell fate.
European journal of immunology 2010;40(9):2608-17.
2010: Nicole A Braun; Yanice V Mendez-Fernandez; Roman Covarrubias; Steven A Porcelli; Paul B Savage; Hideo Yagita; Luc Van Kaer; Amy S Major
Development of spontaneous anergy in invariant natural killer T cells in a mouse model of dyslipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(9):1758-65.
2010: Peter Dias; Francesca Giannoni; Lian Ni Lee; Dongun Han; Sorah Yoon; Hideo Yagita; Miyuki Azuma; Sally R Sarawar
CD4 T-cell help programs a change in CD8 T-cell function enabling effective long-term control of murine gammaherpesvirus 68: role of PD-1-PD-L1 interactions.
Journal of virology 2010;84(16):8241-9.
2010: Hidekazu Oishi; Makoto Sunamura; Shinichi Egawa; Fuyuhiko Motoi; Michiaki Unno; Toru Furukawa; Nagy A Habib; Hideo Yagita
Blockade of delta-like ligand 4 signaling inhibits both growth and angiogenesis of pancreatic cancer.
Pancreas 2010;39(6):897-903.
2010: Nicole M Haynes; Edwin D Hawkins; Ming Li; Nicole M McLaughlin; Günter J Hämmerling; Reto Schwendener; Astar Winoto; Allen Wensky; Hideo Yagita; Kazuyoshi Takeda; Michael H Kershaw; Phillip K Darcy; Mark J Smyth
CD11c+ dendritic cells and B cells contribute to the tumoricidal activity of anti-DR5 antibody therapy in established tumors.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(1):532-41.
2010: Sujin Lee; Hideo Yagita; Thomas J Sayers; Esteban Celis
Optimized combination therapy using bortezomib, TRAIL and TLR agonists in established breast tumors.
Cancer immunology, immunotherapy : CII 2010;59(7):1073-81.
2010: Eijiro Nagasaki; Akitaka Takahara; Shigeo Koido; Yukiko Sagawa; Keisuke Aiba; Hisao Tajiri; Hideo Yagita; Sadamu Homma
Combined treatment with dendritic cells and 5-fluorouracil elicits augmented NK cell-mediated antitumor activity through the tumor necrosis factor-alpha pathway.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(5):467-74.
2010: Junya Fujimura; Kazuyoshi Takeda; Yuki Kaduka; Masahoro Saito; Hisaya Akiba; Hideo Yagita; Yuichiro Yamashiro; Toshiaki Shimizu; Ko Okumura
Contribution of B7RP-1/ICOS co-stimulation to lethal acute GVHD.
Pediatric transplantation 2010;14(4):540-8.
2010: Makiko Ohki; Yuichi Ohki; Makoto Ishihara; Chiemi Nishida; Yoshihiko Tashiro; Haruyo Akiyama; Hiromitsu Komiyama; Leif R Lund; Atsumi Nitta; K Yamada; Zhenping Zhu; Hideoki Ogawa; Hideo Yagita; Ko Okumura; Hiromitsu Nakauchi; Zena Werb; Beate Heissig; Koichi Hattori
Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration.
Blood 2010;115(21):4302-12.
2010: Kazuyoshi Takeda; Yuko Kojima; Tomoyasu Uno; Yoshihiro Hayakawa; Michele W L Teng; Hirohisa Yoshizawa; Hideo Yagita; Fumitake Gejyo; Ko Okumura; Mark J Smyth
Combination therapy of established tumors by antibodies targeting immune activating and suppressing molecules.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(10):5493-501.
2010: Yoichiro Uchida; Bibo Ke; Maria Cecilia S Freitas; Haofeng Ji; Danyun Zhao; Elizabeth R Benjamin; Nader Najafian; Hideo Yagita; Hisaya Akiba; Ronald W Busuttil; Jerzy W Kupiec-Weglinski
The emerging role of T cell immunoglobulin mucin-1 in the mechanism of liver ischemia and reperfusion injury in the mouse.
Hepatology (Baltimore, Md.) 2010;51(4):1363-72.
2010: Tamami Sakanishi; Hideo Yagita
Anti-tumor effects of depleting and non-depleting anti-CD27 monoclonal antibodies in immune-competent mice.
Biochemical and biophysical research communications 2010;393(4):829-35.
2010: David R Gibb; Mohey El Shikh; Dae-Joong Kang; Warren J Rowe; Rania El Sayed; Joanna Cichy; Hideo Yagita; John G Tew; Peter J Dempsey; Howard C Crawford; Daniel H Conrad
ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo.
The Journal of experimental medicine 2010;207(3):623-35.
2010: Sergio Quezada; Tyler R Simpson; Karl S Peggs; Taha Merghoub; Jelena Vider; Xiaozhou Fan; Ronald Blasberg; Hideo Yagita; Pawel Muranski; Paul A Antony; Nicholas P Restifo; James P Allison
Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts.
The Journal of experimental medicine 2010;207(3):637-50.
2010: Satoshi Yanagisawa; Naoya Takeichi; Tomoki Kaneyama; Hideo Yagita; Syun'ichiro Taniguchi; Byung S Kim; Chang-Sung Koh
Effects of anti-CD70 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease.
Brain research 2010;1317():236-45.
2010: Michael A Curran; Welby Montalvo; Hideo Yagita; James P Allison
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(9):4275-80.
2010: Kenji Ishiwata; Naohiro Watanabe; Miao Guo; Kei Tomihara; Michael J Brumlik; Hideo Yagita; Drew M Pardoll; Lieping Chen; Tae Kwang Shin
Costimulator B7-DC attenuates strong Th2 responses induced by Nippostrongylus brasiliensis.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(4):2086-94.
2010: Nadine Kassner; Manuela Krueger; Hideo Yagita; Andrzej Dzionek; Andreas Hutloff; Richard A Kroczek; Alexander Scheffold; Sascha Rutz
Cutting edge: Plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(2):550-4.
2010: Christopher J Chan; Daniel M Andrews; Nicole M McLaughlin; Hideo Yagita; Susan Gilfillan; Marco COLONna; Mark J Smyth
DNAM-1/CD155 interactions promote cytokine and NK cell-mediated suppression of poorly immunogenic melanoma metastases.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(2):902-11.
2010: Tony J Kenna; Tanya Waldie; Alice McNally; Meagan Thomson; Hideo Yagita; Ranjeny Thomas; Raymond J Steptoe
Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(2):598-606.
2010: Geremew Tasew; Susanne Nylén; Thorsten Lieke; Befekadu Lemu; Hailu Meless; Nicolas Ruffin; Dawit Wolday; Abraham Asseffa; Hideo Yagita; Sven Britton; Hannah Akuffo; Francesca Chiodi; liv eidsmo
Systemic FasL and TRAIL neutralisation reduce leishmaniasis induced skin ulceration.
PLoS neglected tropical diseases 2010;4(10):e844.
2010: Elgene Lim; Di Wu; Bhupinder Pal; Toula Bouras; Marie-Liesse Asselin-Labat; François Vaillant; Hideo Yagita; Geoffrey J Lindeman; Gordon K Smyth; Jane E Visvader
Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways.
Breast cancer research : BCR 2010;12(2):R21.
2010: Atsuki Fukushima; Waka Ishida; Ayako Ojima; Mina Kajisako; Tamaki Sumi; Jun Yamada; Emi Tsuru; Jun-ichi Miyazaki; Akira Tominaga; Hideo Yagita
Participation of CD11b and F4/80 molecules in the conjunctival eosinophilia of experimental allergic conjunctivitis.
International archives of allergy and immunology 2010;151(2):129-36.
2009: I Yamato; M Sho; Takeo Nomi; Takahiro Akahori; K Shimada; K Hotta; Hiromichi Kanehiro; N Konishi; Hideo Yagita; Yoshiyuki Nakajima
Clinical importance of B7-H3 expression in human pancreatic cancer.
British journal of cancer 2009;101(10):1709-16.
2009: Kathryn A Knoop; Nachiket Kumar; Betsy R Butler; Senthilkumar K Sakthivel; Rebekah T Taylor; Tomonori Nochi; Hisaya Akiba; Hideo Yagita; Hiroshi Kiyono; Ifor Williams
RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(9):5738-47.
2009: Paul Ojiambo Wafula; Ana Teles; Anne Schumacher; Kerstin Pohl; Hideo Yagita; Hans-Dieter Volk; Ana Claudia Zenclussen
PD-1 but not CTLA-4 blockage abrogates the protective effect of regulatory T cells in a pregnancy murine model.
American journal of reproductive immunology (New York, N.Y. : 1989) 2009;62(5):283-92.
2009: Yoshie Kametani; Daisuke Suzuki; Kazuyoshi Kohu; Masanobu Satake; Hiroshi Suemizu; Erika Sasaki; Toshio Ito; Norikazu Tamaoki; Tomoko Mizushima; manabu ozawa; Kenzaburo Tani; Mitsuaki Kito; Hideo Arai; Akemi Koyanagi; Hideo Yagita; Sonoko Habu
Development of monoclonal antibodies for analyzing immune and hematopoietic systems of common marmoset.
Experimental hematology 2009;37(11):1318-29.
2009: Hong Dai; Huifen Zhu; Ping Lei; Hideo Yagita; Jing Liu; Xue Wen; Wei Zhou; Feili Gong; Guanxin Shen; Min Fang
Programmed death-1 signaling is essential for the skin allograft protection by alternatively activated dendritic cell infusion in mice.
Transplantation 2009;88(7):864-73.
2009: Keisuke Okudaira; Ryota Hokari; Yoshikazu Tsuzuki; Yoshikiyo Okada; Shunsuke Komoto; Chikako Watanabe; Chie Kurihara; Atsushi Kawaguchi; Shigeaki Nagao; Miyuki Azuma; Hideo Yagita; Soichiro Miura
Blockade of B7-H1 or B7-DC induces an anti-tumor effect in a mouse pancreatic cancer model.
International journal of oncology 2009;35(4):741-9.
2009: Atef Allam; Dietrich B Conze; Maria Letizia Giardino Torchia; Ivana Munitic; Hideo Yagita; Ryan T Sowell; Amanda L Marzo; Jonathan D Ashwell
The CD8+ memory T-cell state of readiness is actively maintained and reversible.
Blood 2009;114(10):2121-30.
2009: Quang-Tam Nguyen; Seong-A Ju; Sang-Min Park; Sang-Chul Lee; Hideo Yagita; In Hee Lee; Byung-Sam Kim
Blockade of CD137 signaling counteracts polymicrobial sepsis induced by cecal ligation and puncture.
Infection and immunity 2009;77(9):3932-8.
2009: Anil Shanker; Alan D Brooks; Kristen M Jacobsen; John W Wine; Robert Wiltrout; Hideo Yagita; Thomas J Sayers
Antigen presented by tumors in vivo determines the nature of CD8+ T-cell cytotoxicity.
Cancer research 2009;69(16):6615-23.
2009: Bhawna Poonia; Maria Salvato; Hideo Yagita; Toshihiro Maeda; Ko Okumura; C. David Pauza
Treatment with anti-FasL antibody preserves memory lymphocytes and virus-specific cellular immunity in macaques challenged with simian immunodeficiency virus.
Blood 2009;114(6):1196-204.
2009: Luciana Lorena Molinero; Ying Wang; Ping Zhou; Hideo Yagita; Maria-Luisa Alegre
Fas mediates cardiac allograft acceptance in mice with impaired T-cell-intrinsic NF-kappaB signaling.
Transplant international : official journal of the European Society for Organ Transplantation 2009;22(8):845-52.
2009: Dalit Tchorsh-Yutsis; Gil Hecht; Anna Aronovich; Elias Shezen; Yael Klionsky; Chava Rosen; Rivka Bitcover; Smadar Eventov-Friedman; Helena Katchman; Sivan Cohen; Orna Tal; Oren Milstein; Hideo Yagita; Bruce R Blazar; Yair Reisner
Pig embryonic pancreatic tissue as a source for transplantation in diabetes: transient treatment with anti-LFA1, anti-CD48, and FTY720 enables long-term graft maintenance in mice with only mild ongoing immunosuppression.
Diabetes 2009;58(7):1585-94.
2009: Xueli Yuan; Mohammed Javeed I Ansari; Francesca D'Addio; Jesus Paez-Cortez; Isabella Schmitt; Michela Donnarumma; Olaf Boenisch; Xiaozhi Zhao; Joyce Popoola; Michael R Clarkson; Hideo Yagita; Hisaya Akiba; Gordon J Freeman; John Iacomini; Laurence A Turka; Laurie H Glimcher; Mohamed H Sayegh
Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(26):10734-9.
2009: Kyoko Haraguchi; Takahiro Suzuki; Noriko Koyama; Keiki Kumano; Fumio Nakahara; Akihiko Matsumoto; Yasuhisa Yokoyama; Mamiko Sakata-Yanagimoto; Shigeo Masuda; Tsuyoshi Takahashi; Aki Kamijo; Koki Takahashi; Minoko Takanashi; Yoshiki Okuyama; Koji Yasutomo; Seiji Sakano; Hideo Yagita; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba
Notch activation induces the generation of functional NK cells from human cord blood CD34-positive cells devoid of IL-15.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6168-78.
2009: Teruji Totsuka; Takanori Kanai; Yasuhiro Nemoto; Takayuki Tomita; Ryuichi Okamoto; Kiichiro Tsuchiya; Tetsuya Nakamura; Naoya Sakamoto; Hisaya Akiba; Ko Okumura; Hideo Yagita; Mamoru Watanabe
RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T cells in chronic colitis.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6079-87.
2009: Suk-young Lee; Keiki Kumano; Kumi Nakazaki; Masashi Sanada; Akihiko Matsumoto; Go Yamamoto; Yasuhito Nannya; Ritsuro Suzuki; Satoshi Ota; Yasunori Ota; Koji Izutsu; Mamiko Sakata-Yanagimoto; Akira Hangaishi; Hideo Yagita; Masashi Fukayama; Masao Seto; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba
Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma.
Cancer science 2009;100(5):920-6.
2009: Jun Yamada; Junji Hamuro; Atsuki Fukushima; Toshiaki Ohteki; Kazuto Terai; Yoichiro Iwakura; Hideo Yagita; Shigeru Kinoshita
MHC-matched corneal allograft rejection in an IFN-gamma/IL-17-independent manner in C57BL/6 mice.
Investigative ophthalmology & visual science 2009;50(5):2139-46.
2009: Masafumi Nakayama; Hisaya Akiba; Kazuyoshi Takeda; Yuko Kojima; Masaaki Hashiguchi; Miyuki Azuma; Hideo Yagita; Ko Okumura
Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation.
Blood 2009;113(16):3821-30.
2009: Shinsuke Yamanda; Satoru Ebihara; Masanori Asada; Tatsuma Okazaki; Kaijun Niu; Takae Ebihara; Akemi Koyanagi; Noriko Yamaguchi; Hideo Yagita; Hiroyuki Arai
Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockade.
Blood 2009;113(15):3631-9.
2009: Yoshihiko Usui; Masaru Takeuchi; Takaaki Hattori; Yoko Okunuki; Kazumi Nagasawa; Takeshi Kezuka; Ko Okumura; Hideo Yagita; Hisaya Akiba; Hiroshi Goto
Suppression of experimental autoimmune uveoretinitis by regulatory dendritic cells in mice.
Archives of ophthalmology 2009;127(4):514-9.
2009: Shinichiro Fuse; Ching-Yi Tsai; Michael J Molloy; S Rameeza Allie; Weijun Zhang; Hideo Yagita; Edward J Usherwood
Recall responses by helpless memory CD8+ T cells are restricted by the up-regulation of PD-1.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(7):4244-54.
2009: Michio Onizawa; Takashi Nagaishi; Takanori Kanai; Ken-ichi Nagano; Shigeru Oshima; Yasuhiro Nemoto; Atsushi Yoshioka; Teruji Totsuka; Ryuichi Okamoto; Tetsuya Nakamura; Naoya Sakamoto; Kiichiro Tsuchiya; Kazuhiro Aoki; Keiichi Ohya; Hideo Yagita; Mamoru Watanabe
Signaling pathway via TNF-alpha/NF-kappaB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis.
American journal of physiology. Gastrointestinal and liver physiology 2009;296(4):G850-9.
2009: Mika Kijima; Akiko Iwata; Yoichi Maekawa; Hisanori Uehara; Keisuke Izumi; Akiko Kitamura; Hideo Yagita; Shigeru Chiba; Hiroshi Shiota; Koji Yasutomo
Jagged1 suppresses collagen-induced arthritis by indirectly providing a negative signal in CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3566-72.
2009: Vrajesh V Parekh; Saif Lalani; Sungjune Kim; Ramesh Halder; Miyuki Azuma; Hideo Yagita; Vipin Kumar; Lan Wu; Luc Van Kaer
PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(5):2816-26.
2009: Adam T C Cheuk; James W Wells; Lucas Chan; Nigel B Westwood; Stuart A Berger; Hideo Yagita; Ko Okumura; Farzin Farzaneh; Ghulam J Mufti; Barbara-Ann Guinn
Anti-tumor immunity in a model of acute myeloid leukemia.
Leukemia & lymphoma 2009;50(3):447-54.
2009: Chiyoko Sekine; Yuko Moriyama; Akemi Koyanagi; Noriko Koyama; Hideko Ogata; Ko Okumura; Hideo Yagita
Differential regulation of splenic CD8- dendritic cells and marginal zone B cells by Notch ligands.
International immunology 2009;21(3):295-301.
2009: Catrine M Persson; Henrik Lambert; Polya P Vutova; Isabel Dellacasa-Lindberg; Joanna Nederby; Hideo Yagita; Hans-Gustaf Ljunggren; Alf Grandien; Antonio Barragan; Benedict J Chambers
Transmission of Toxoplasma gondii from infected dendritic cells to natural killer cells.
Infection and immunity 2009;77(3):970-6.
2009: Esther Tamayo; Jorge Postigo; Giuseppe Del Giudice; Rino Rappuoli; Adalberto Benito; Hideo Yagita; Ramón Merino; Jesús Merino
Involvement of the intrinsic and extrinsic cell-death pathways in the induction of apoptosis of mature lymphocytes by the Escherichia coli heat-labile enterotoxin.
European journal of immunology 2009;39(2):439-46.
2009: Deepak Yadav; Natasha Hill; Hideo Yagita; Miyuki Azuma; Nora Sarvetnick
Altered availability of PD-1/PD ligands is associated with the failure to control autoimmunity in NOD mice.
Cellular immunology 2009;258(2):161-71.
2009: Nobuhiro Nakano; Chiharu Nishiyama; Hideo Yagita; Akemi Koyanagi; Hisaya Akiba; Shigeru Chiba; Hideoki Ogawa; Ko Okumura
Notch signaling confers antigen-presenting cell functions on mast cells.
The Journal of allergy and clinical immunology 2009;123(1):74-81.e1.
2009: Toshihiko Kawamura; K Takeda; Hiroshi Kaneda; Hiroaki Matsumoto; Yoshihiro Hayakawa; David H Raulet; Yoshinori Ikarashi; Mitchell Kronenberg; Hideo Yagita; Katsuyuki Kinoshita; Toru Abo; Ko Okumura; Mark J Smyth
NKG2A inhibits invariant NKT cell activation in hepatic injury.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(1):250-8.
2009: Tamaki Sumi; Waka Ishida; Robert S Mittler; Hideo Yagita; Osamu Taguchi; Atsuki Fukushima
Regulatory T cells participate in 4-1BB-mediated suppression of experimental allergic conjunctivitis.
International archives of allergy and immunology 2009;148(4):305-10.
2008: Woo-Sung Chang; JY Kim; Yeon Jeong Kim; Yun-Sun Kim; Jung-Mi Lee; Miyuki Azuma; Hideo Yagita; Chang-Yuil Kang
Cutting edge: Programmed death-1/programmed death ligand 1 interaction regulates the induction and maintenance of invariant NKT cell anergy.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(10):6707-10.
2008: Stephan Roux; Lionel Apetoh; Fanny Chalmin; Sylvain Ladoire; Grégoire Mignot; Pierre-Emmanuel Puig; Gregoire Lauvau; Laurence Zitvogel; François Martin; Bruno Chauffert; Hideo Yagita; Eric Solary; François Ghiringhelli
CD4+CD25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer.
The Journal of clinical investigation 2008;118(11):3751-61.
2008: Yasuhiro Nemoto; Takanori Kanai; Shuji Tohda; Teruji Totsuka; Ryuichi Okamoto; Kiichiro Tsuchiya; Tetsuya Nakamura; Naoya Sakamoto; Tetsuya Fukuda; Osamu Miura; Hideo Yagita; Mamoru Watanabe
Negative feedback regulation of colitogenic CD4+ T cells by increased granulopoiesis.
Inflammatory bowel diseases 2008;14(11):1491-503.
2008: John Stagg; Janelle Sharkey; Sandra Pommey; Richard Young; Kazuyoshi Takeda; Hideo Yagita; Ricky Johnstone; Mark J Smyth
Antibodies targeted to TRAIL receptor-2 and ErbB-2 synergize in vivo and induce an antitumor immune response.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(42):16254-9.
2008: Koji Atarashi; Junichi Nishimura; Tatsuichiro Shima; Yoshinori Umesaki; Masahiro Yamamoto; Masaharu Onoue; Hideo Yagita; Naoto Ishii; Richard Evans; Kenya Honda; Kiyoshi Takeda
ATP drives lamina propria T(H)17 cell differentiation.
Nature 2008;455(7214):808-12.
2008: Yoichi Maekawa; Yoshiaki Minato; Chieko Ishifune; Takeshi Kurihara; Akiko Kitamura; Hidefumi Kojima; Hideo Yagita; Mamiko Sakata-Yanagimoto; Toshiki Saito; Ichiro Taniuchi; Shigeru Chiba; Saburo Sone; Koji Yasutomo
Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.
Nature immunology 2008;9(10):1140-7.
2008: Akiko Ito; Hideki Shimura; Ayano Nitahara; Katsuhiro Tomiyama; Masaaki Ito; Takuro Kanekura; Ko Okumura; Hideo Yagita; Kazuhiro Kawai
NK cells contribute to the skin graft rejection promoted by CD4+ T cells activated through the indirect allorecognition pathway.
International immunology 2008;20(10):1343-9.
2008: Kumiko Saeki; Yoshiko Yogiashi; Masako Nakahara; Naoko Nakamura; Satoko Matsuyama; Akemi Koyanagi; Hideo Yagita; Makoto Koyanagi; Yasushi Kondo; Akira Yuo
Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells.
Journal of cellular physiology 2008;217(1):261-80.
2008: Taisuke Sawada; Chiharu Nishiyama; Takuma Kishi; Tomonari Sasazuki; Sachiko Komazawa-Sakon; Xin Xue; Jiang-Hu Piao; Hideko Ogata; Jun-ichi Nakayama; Tomohiko Taki; Yasuhide Hayashi; Mamoru Watanabe; Hideo Yagita; Ko Okumura; Hiroyasu Nakano
Fusion of OTT to BSAC results in aberrant up-regulation of transcriptional activity.
The Journal of biological chemistry 2008;283(39):26820-8.
2008: Osamu Nagashima; Norihiro Harada; Yoshihiko Usui; Tomohide Yamazaki; Hideo Yagita; Ko Okumura; Kazuhisa Takahashi; Hisaya Akiba
B7-H3 contributes to the development of pathogenic Th2 cells in a murine model of asthma.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):4062-71.
2008: Jean-Sébastien Delisle; Louis Gaboury; Marie-Pier Bélanger; Eliane Tassé; Hideo Yagita; Claude Perreault
Graft-versus-host disease causes failure of donor hematopoiesis and lymphopoiesis in interferon-gamma receptor-deficient hosts.
Blood 2008;112(5):2111-9.
2008: Akihito Nakajima; Hidetake Kurihara; Hideo Yagita; Ko Okumura; Hiroyasu Nakano
Mitochondrial Extrusion through the cytoplasmic vacuoles during cell death.
The Journal of biological chemistry 2008;283(35):24128-35.
2008: Tamaki Sumi; Waka Ishida; Ayako Ojima; Minako Kajisako; Tamami Sakanishi; Hideo Yagita; Atsuki Fukushima
CD27 and CD70 do not play a critical role in the development of experimental allergic conjunctivitis in mice.
Immunology letters 2008;119(1-2):91-6.
2008: Ailsa J Frew; Ralph K Lindemann; Ben P Martin; chris clarke; Janelle Sharkey; Desiree A Anthony; Kellie-Marie Banks; Nicole M Haynes; Pradnya Gangatirkar; Kym Stanley; Jessica E Bolden; Kazuyoshi Takeda; Hideo Yagita; J Paul Secrist; Mark J Smyth; Ricky Johnstone
Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(32):11317-22.
2008: Chih Wen Tseng; Archana Monie; Cornelia L Trimble; Ronald D Alvarez; Warner K Huh; Donald J Buchsbaum; J Michael Straughn; Mei-Cheng Wang; Hideo Yagita; Chien-Fu Hung; Tzyy-choou Wu
Combination of treatment with death receptor 5-specific antibody with therapeutic HPV DNA vaccination generates enhanced therapeutic anti-tumor effects.
Vaccine 2008;26(34):4314-9.
2008: Kazuyoshi Takeda; Yuko Kojima; Kenichi Ikejima; Kenichi Harada; Shunhei Yamashina; Kyoko Okumura; Tomonori Aoyama; Steffen Frese; Hiroko Ikeda; Nicole M Haynes; Erika Cretney; Hideo Yagita; Noriyoshi Sueyoshi; Nobuhiro Sato; Yasuni Nakanuma; Mark J Smyth; Ko Okumura
Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10895-900.
2008: Wassim Elyaman; Pia Kivisäkk; Jayagopala Reddy; Tanuja Chitnis; Khadir Raddassi; Jaime Imitola; Elizabeth Bradshaw; Vijay K Kuchroo; Hideo Yagita; Mohamed H Sayegh; Samia J Khoury
Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis.
The American journal of pathology 2008;173(2):411-22.
2008: Hiroo Nakajima; Naruhiko Mizuta; Ikuya Fujiwara; Koichi Sakaguchi; Hiromitsu Ogata; Junji Magae; Hideo Yagita; Takehiko Koji
Blockade of the Fas/Fas ligand interaction suppresses hepatocyte apoptosis in ischemia-reperfusion rat liver.
Apoptosis : an international journal on programmed cell death 2008;13(8):1013-21.
2008: Andrey Mikhailov; Alice Sokolovskaya; Gennady G Yegutkin; Hanne Amdahl; Anne West; Hideo Yagita; Riitta Lahesmaa; Linda F Thompson; Sirpa Jalkanen; Dmitry Blokhin; John E Eriksson
CD73 participates in cellular multiresistance program and protects against TRAIL-induced apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(1):464-75.
2008: Shunsuke Kanada; Nobuhiro Nakano; Daniel P Potaczek; Keiko Maeda; Naomi Shimokawa; Yusuke Niwa; Tatsuo Fukai; Marek Sanak; Andrew Szczeklik; Hideo Yagita; Ko Okumura; Hideoki Ogawa; Chiharu Nishiyama
Two different transcription factors discriminate the -315C>T polymorphism of the Fc epsilon RI alpha gene: binding of Sp1 to -315C and of a high mobility group-related molecule to -315T.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):8204-10.
2008: Kazuyoshi Kohu; Eiji Yamabe; Ayako Matsuzawa; Daisuke Onda; Hiroshi Suemizu; Erika Sasaki; Yoshikuni Tanioka; Hideo Yagita; Daisuke Suzuki; Yoshie Kametani; Toshiyuki Takai; Atsushi Toyoda; Sonoko Habu; Masanobu Satake
Comparison of 30 immunity-related genes from the common marmoset with orthologues from human and mouse.
The Tohoku journal of experimental medicine 2008;215(2):167-80.
2008: Yuko Moriyama; Chiyoko Sekine; Akemi Koyanagi; Noriko Koyama; Hideko Ogata; Shigeru Chiba; Sachiko Hirose; Ko Okumura; Hideo Yagita
Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice.
International immunology 2008;20(6):763-73.
2008: Mika Kijima; Takeshi Yamaguchi; Chieko Ishifune; Yoichi Maekawa; Akemi Koyanagi; Hideo Yagita; Shigeru Chiba; Kenji Kishihara; Mitsuo Shimada; Koji Yasutomo
Dendritic cell-mediated NK cell activation is controlled by Jagged2-Notch interaction.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(19):7010-5.
2008: Anil Shanker; Alan David Brooks; Carlos Alberto Tristan; John William Wine; Peter John Elliott; Hideo Yagita; Kazuyoshi Takeda; Mark John Smyth; William Murphy; Thomas Joseph Sayers
Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody.
Journal of the National Cancer Institute 2008;100(9):649-62.
2008: Mark J Smyth; Michele W L Teng; Janelle Sharkey; Jennifer A Westwood; Nicole M Haynes; Hideo Yagita; Kazuyoshi Takeda; Pallavur V Sivakumar; Michael H Kershaw
Interleukin 21 enhances antibody-mediated tumor rejection.
Cancer research 2008;68(8):3019-25.
2008: Kristy L Edgtton; Joshua Y Kausman; Ming Li; Kim M O'Sullivan; Cecilia Lo; Paul Hutchinson; Hideo Yagita; Stephen R Holdsworth; A Richard Kitching
Intrarenal antigens activate CD4+ cells via co-stimulatory signals from dendritic cells.
Journal of the American Society of Nephrology : JASN 2008;19(3):515-26.
2008: Arnaud Couzinet; Kaoru Tamura; Hui-Min Chen; Keishiro Nishimura; Zhichao Wang; Yasuyuki Morishita; Kazuyoshi Takeda; Hideo Yagita; Hideyuki Yanai; Tadatsugu Taniguchi; Tomohiko Tamura
A cell-type-specific requirement for IFN regulatory factor 5 (IRF5) in Fas-induced apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2556-61.
2008: Jun Yang; Joyce Popoola; Shakila Khandwala; Nidyanandh Vadivel; Vijay Vanguri; Xueli Yuan; Shirine Dada; Indira Guleria; Chaorui Tian; Mohammed Javeed I Ansari; Tae Kwang Shin; Hideo Yagita; Miyuki Azuma; Mohamed H Sayegh; Anil Chandraker
Critical role of donor tissue expression of programmed death ligand-1 in regulating cardiac allograft rejection and vasculopathy.
Circulation 2008;117(5):660-9.
2008: Takuya Ueno; Antje Habicht; Michael R Clarkson; Monica J Albin; Kazuhiro Yamaura; Olaf Boenisch; Joyce Popoola; Ying Wang; Hideo Yagita; Hisaya Akiba; Mohammed Javeed I Ansari; Jaeseok Yang; Laurence A Turka; David M Rothstein; Robert F Padera; Nader Najafian; Mohamed H Sayegh
The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model.
The Journal of clinical investigation 2008;118(2):742-51.
2008: Koichiro Matsumoto; Satoru Fukuyama; Miyuki Eguchi-Tsuda; Takako Nakano; Takafumi Matsumoto; Mikiko Matsumura; Atsushi Moriwaki; Keiko Kan-o; Yoshihiro Wada; Hideo Yagita; Tae Kwang Shin; Drew M Pardoll; Rirprajak Patcharee; Miyuki Azuma; Yoichi Nakanishi; Hiromasa Inoue
B7-DC induced by IL-13 works as a feedback regulator in the effector phase of allergic asthma.
Biochemical and biophysical research communications 2008;365(1):170-5.
2008: A Nakajima; Y Kojima; M Nakayama; Hideo Yagita; Ko Okumura; Hiroyasu Nakano
Downregulation of c-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells.
Oncogene 2008;27(1):76-84.
2008: Abdiaziz S Mohamood; Dylan Bargatze; Zuoxiang Xiao; Chunfa Jie; Hideo Yagita; DAWN RUBEN; Julie Watson; Shukti Chakravarti; Jonathan P Schneck; Abdel Rahim A Hamad
Fas-mediated apoptosis regulates the composition of peripheral alphabeta T cell repertoire by constitutively purging out double negative T cells.
PloS one 2008;3(10):e3465.
2008: Atsuki Fukushima; Tamaki Sumi; Ken Fukuda; Naoki Kumagai; Teruo Nishida; Ko Okumura; Hisaya Akiba; Hideo Yagita; Hisayuki Ueno
Roles of galectin-9 in the development of experimental allergic conjunctivitis in mice.
International archives of allergy and immunology 2008;146(1):36-43.
2008: Yoshiaki Ito; Takanori Kanai; Teruji Totsuka; Ryuichi Okamoto; Ken Tsuchiya; Yasuhiro Nemoto; A Yoshioka; T Tomita; T Nagaishi; N Sakamoto; T Sakanishi; Ko Okumura; Hideo Yagita; Masahiko Watanabe
Blockade of NKG2D signaling prevents the development of murine CD4+ T cell-mediated colitis.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(1):G199-207.
2007: Emma K Persson; Abela Mpobela Agnarson; Henrik Lambert; Niclas Hitziger; Hideo Yagita; Benedict J Chambers; Antonio Barragan; Alf Grandien
Death receptor ligation or exposure to perforin trigger rapid egress of the intracellular parasite Toxoplasma gondii.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(12):8357-65.
2007: Takaaki Hattori; Yoshihiko Usui; Yoko Okunuki; Yasushi Sonoda; Masahiko Usui; Eiko Takada; Junichiro Mizuguchi; Hideo Yagita; Ko Okumura; Hisaya Akiba; Masaru Takeuchi
Blockade of the OX40 ligand prolongs corneal allograft survival.
European journal of immunology 2007;37(12):3597-604.
2007: Anne Schumacher; Paul O Wafula; Annarosa Zambon Bertoja; Andre Sollwedel; Catharina Thuere; Ivonne Wollenberg; Hideo Yagita; Hans-Dieter Volk; Ana Zenclussen
Mechanisms of action of regulatory T cells specific for paternal antigens during pregnancy.
Obstetrics and gynecology 2007;110(5):1137-45.
2007: Wassim Elyaman; Elizabeth M Bradshaw; Yue Wang; Mohamed Oukka; Pia Kivisäkk; Shigeru Chiba; Hideo Yagita; Samia J Khoury
JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):5990-8.
2007: Markus Weckmann; Adam Collison; Jodie L Simpson; Matthias Volkmar Kopp; Peter A B Wark; Mark J Smyth; Hideo Yagita; Klaus I Matthaei; Nicole Hansbro; Bruce Whitehead; Peter G Gibson; Paul S Foster; Joerg Mattes
Critical link between TRAIL and CCL20 for the activation of TH2 cells and the expression of allergic airway disease.
Nature medicine 2007;13(11):1308-15.
2007: Atsuki Fukushima; Tamaki Sumi; Ken Fukuda; Naoki Kumagai; Teruo Nishida; Yamazaki Tomohide; Hisaya Akiba; Ko Okumura; Hideo Yagita; Hisayuki Ueno
B7-H3 regulates the development of experimental allergic conjunctivitis in mice.
Immunology letters 2007;113(1):52-7.
2007: Antje Habicht; Shirine Dada; Mollie Jurewicz; Brian T Fife; Hideo Yagita; Miyuki Azuma; Mohamed H Sayegh; Indira Guleria
A link between PDL1 and T regulatory cells in fetomaternal tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5211-9.
2007: Katsunori Tanaka; Monica J Albin; Xueli Yuan; Kazuhiro Yamaura; Antje Habicht; Takaya Murayama; Martin Grimm; Ana Maria Waaga; Takuya Ueno; Robert F Padera; Hideo Yagita; Miyuki Azuma; Tae Kwang Shin; Bruce R Blazar; David M Rothstein; Mohamed H Sayegh; Nader Najafian
PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5204-10.
2007: Indira Guleria; Melanie Gubbels Bupp; Shirine Dada; Brian T Fife; Qizhi Tang; Mohammed Javeed I Ansari; Subbulaxmi Trikudanathan; Nidyanandh Vadivel; Paolo Fiorina; Hideo Yagita; Miyuki Azuma; Mark Atkinson; Jeffrey A Bluestone; Mohamed H Sayegh
Mechanisms of PDL1-mediated regulation of autoimmune diabetes.
Clinical immunology (Orlando, Fla.) 2007;125(1):16-25.
2007: Madhav D Sharma; Babak Baban; Phillip R Chandler; Deyan Hou; Nagendra Singh; Hideo Yagita; Miyuki Azuma; Bruce R Blazar; Andrew L Mellor; David H Munn
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase.
The Journal of clinical investigation 2007;117(9):2570-82.
2007: Ilia Voskoboinik; Vivien R Sutton; Annette Ciccone; Colin M House; Jenny Chia; Phillip K Darcy; Hideo Yagita; Joseph A Trapani
Perforin activity and immune homeostasis: the common A91V polymorphism in perforin results in both presynaptic and postsynaptic defects in function.
Blood 2007;110(4):1184-90.
2007: Michele W L Teng; Jennifer A Westwood; Phillip K Darcy; Janelle Sharkey; Moriya Tsuji; Richard W Franck; Steven A Porcelli; Gurdyal S Besra; Kazuyoshi Takeda; Hideo Yagita; Michael H Kershaw; Mark J Smyth
Combined natural killer T-cell based immunotherapy eradicates established tumors in mice.
Cancer research 2007;67(15):7495-504.
2007: Antje Habicht; Nader Najafian; Hideo Yagita; Mohamed H Sayegh; Michael R Clarkson
New insights in CD28-independent allograft rejection.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(8):1917-26.
2007: Atsushi Izawa; Kazuhiro Yamaura; Monica J Albin; Mollie Jurewicz; Katsunori Tanaka; Michael R Clarkson; Takuya Ueno; Antje Habicht; Gordon J Freeman; Hideo Yagita; Reza Abdi; Todd Pearson; Dale L Greiner; Mohamed H Sayegh; Nader Najafian
A novel alloantigen-specific CD8+PD1+ regulatory T cell induced by ICOS-B7h blockade in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):786-96.
2007: Juyang Kim; Hye J Kim; Keunhee Park; Jiyoung Kim; Hye-Jeong Choi; Hideo Yagita; Seok Hyun Nam; Hong Rae Cho; Byungsuk Kwon
Costimulatory molecule-targeted immunotherapy of cutaneous graft-versus-host disease.
Blood 2007;110(2):776-82.
2007: Sheng Xiao; Nader Najafian; Jayagopala Reddy; Monica J Albin; Chen Zhu; Eric Jensen; Jaime Imitola; Thomas Korn; Ana C Anderson; Zheng Zhang; Cristina Gutierrez; Thomas Moll; Raymond A Sobel; Dale T Umetsu; Hideo Yagita; Hisaya Akiba; Terry Strom; Mohamed H Sayegh; Rosemarie H Dekruyff; Samia J Khoury; Vijay K Kuchroo
Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function.
The Journal of experimental medicine 2007;204(7):1691-702.
2007: Abdiaziz S Mohamood; Mehmet L Guler; Zuoxiang Xiao; Dongfeng Zheng; Allan Hess; Yi Wang; Hideo Yagita; Jonathan P Schneck; Abdel Rahim A Hamad
Protection from autoimmune diabetes and T-cell lymphoproliferation induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically.
The American journal of pathology 2007;171(1):97-106.
2007: Amanda L Marzo; Hideo Yagita; Leo Lefrançois
Cutting edge: migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(1):36-40.
2007: Yoshinori Seko; Hideo Yagita; Ko Okumura; Miyuki Azuma; Ryozo Nagai
Roles of programmed death-1 (PD-1)/PD-1 ligands pathway in the development of murine acute myocarditis caused by coxsackievirus B3.
Cardiovascular research 2007;75(1):158-67.
2007: Atsuki Fukushima; Tamaki Sumi; Ken Fukuda; Naoki Kumagai; Teruo Nishida; Ko Okumura; Hisaya Akiba; Hideo Yagita; Hisayuki Ueno
T-cell Ig and mucin domain-containing protein (Tim)-2 regulates murine allergic conjunctivitis during the effector phase.
Immunology letters 2007;110(2):133-8.
2007: Kazuyoshi Takeda; J Stagg; Hideo Yagita; Ko Okumura; Mark J Smyth
Targeting death-inducing receptors in cancer therapy.
Oncogene 2007;26(25):3745-57.
2007: Helena Soares; HaeNa Waechter; Nicolas Glaichenhaus; Evelyne Mougneau; Hideo Yagita; Olga Mizenina; Diana Dudziak; Michel C Nussenzweig; Ralph M Steinman
A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo.
The Journal of experimental medicine 2007;204(5):1095-106.
2007: Shinichiro Fuse; Sarah C Bellfy; Hideo Yagita; Edward J Usherwood
CD8+ T cell dysfunction and increase in murine gammaherpesvirus latent viral burden in the absence of 4-1BB ligand.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(8):5227-36.
2007: Takeo Nomi; Masayuki Sho; Takahiro Akahori; Kaoru Hamada; Atsushi Kubo; Hiromichi Kanehiro; Shinji Nakamura; Koji Enomoto; Hideo Yagita; Miyuki Azuma; Yoshiyuki Nakajima
Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(7):2151-7.
2007: Landi V C Guillermo; Elisabeth M Silva; Flávia L Ribeiro-Gomes; Juliana De Meis; Wânia F Pereira; Hideo Yagita; George A DosReis; Marcela F Lopes
The Fas death pathway controls coordinated expansions of type 1 CD8 and type 2 CD4 T cells in Trypanosoma cruzi infection.
Journal of leukocyte biology 2007;81(4):942-51.
2007: Anita Schildknecht; Iris Miescher; Hideo Yagita; Maries van den Broek
Priming of CD8+ T cell responses by pathogens typically depends on CD70-mediated interactions with dendritic cells.
European journal of immunology 2007;37(3):716-28.
2007: Andrew J Lepisto; Min Xu; Hideo Yagita; Andrew D Weinberg; Robert L Hendricks
Expression and function of the OX40/OX40L costimulatory pair during herpes stromal keratitis.
Journal of leukocyte biology 2007;81(3):766-74.
2007: Jiang-Hu Piao; Hisahiro Yoshida; Wen-Chen Yeh; Takahiro Doi; Xin Xue; Hideo Yagita; Ko Okumura; Hiroyasu Nakano
TNF receptor-associated factor 2-dependent canonical pathway is crucial for the development of Peyer's patches.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2272-7.
2007: Atsuki Fukushima; Tamaki Sumi; Ken Fukuda; Naoki Kumagai; Teruo Nishida; Hisaya Akiba; Ko Okumura; Hideo Yagita; Hisayuki Ueno
Antibodies to T-cell Ig and mucin domain-containing proteins (Tim)-1 and -3 suppress the induction and progression of murine allergic conjunctivitis.
Biochemical and biophysical research communications 2007;353(1):211-6.
2007: Phillip J Sanchez; Jennifer A McWilliams; Catherine Haluszczak; Hideo Yagita; Ross M Kedl
Combined TLR/CD40 stimulation mediates potent cellular immunity by regulating dendritic cell expression of CD70 in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1564-72.
2007: Amale Laouar; Monika Manocha; Meimei Wan; Hideo Yagita; René A W van Lier; N Manjunath
Cutting Edge: Distinct NK receptor profiles are imprinted on CD8 T cells in the mucosa and periphery during the same antigen challenge: role of tissue-specific factors.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(2):652-6.
2007: Tamaki Sumi; Atsuki Fukushima; Ken Fukuda; Naoki Kumagai; Teruo Nishida; Hideo Yagita; Hisayuki Ueno
Differential contributions of B7-1 and B7-2 to the development of murine experimental allergic conjunctivitis.
Immunology letters 2007;108(1):62-7.
2007: Maria Salvato; C Cameron Yin; Hideo Yagita; Toshihiro Maeda; Ko Okumura; Ilia Tikhonov; C. David Pauza
Attenuated disease in SIV-infected macaques treated with a monoclonal antibody against FasL.
Clinical & developmental immunology 2007;2007():93462.
2007: Eva J A van Wanrooij; Gijs van Puijvelde; Paula de Vos; Hideo Yagita; Theo Van berkel; Johan Kuiper
Interruption of the Tnfrsf4/Tnfsf4 (OX40/OX40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(1):204-10.
2006: Natalia Martin-Orozco; Yi-Hong Wang; Hideo Yagita; Chen Dong
Cutting Edge: Programmed death (PD) ligand-1/PD-1 interaction is required for CD8+ T cell tolerance to tissue antigens.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(12):8291-5.
2006: Mahasweta Girgenrath; Shawn Weng; Christine A Kostek; Beth Browning; Monica Wang; Sharron A N Brown; Jeffrey A Winkles; Jennifer S Michaelson; Normand E Allaire; Pascal Schneider; Martin L Scott; Yen-Ming Hsu; Hideo Yagita; Richard A Flavell; Jeffrey Boone Miller; Linda C Burkly; Timothy S Zheng
TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration.
The EMBO journal 2006;25(24):5826-39.
2006: Takeshi Inukai; Xiaochun Zhang; M Goto; Kinuko Hirose; Kanako Uno; Koshi Akahane; Atsushi Nemoto; Kumiko Goi; Hiroki Sato; Kazuya Takahashi; Hiroko Honna; Keiko Kagami; K Nakamoto; Hideo Yagita; Ko Okumura; T Koyama-Okazaki; Shinpei Nakazawa; Kanji Sugita
Resistance of infant leukemia with MLL rearrangement to tumor necrosis factor-related apoptosis-inducing ligand: a possible mechanism for poor sensitivity to antitumor immunity.
Leukemia 2006;20(12):2119-29.
2006: Atsuki Fukushima; Tamaki Sumi; Ken Fukuda; Naoki Kumagai; Teruo Nishida; Hideo Yagita; Hiasyuki Ueno
Interleukin 10 and transforming growth factor beta contribute to the development of experimentally induced allergic conjunctivitis in mice during the effector phase.
The British journal of ophthalmology 2006;90(12):1535-41.
2006: Akihito Nakajima; Sachiko Komazawa-Sakon; Mutsuhiro Takekawa; Tomonari Sasazuki; Wen-Chen Yeh; Hideo Yagita; Ko Okumura; Hiroyasu Nakano
An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway.
The EMBO journal 2006;25(23):5549-59.
2006: Brian T Fife; Indira Guleria; Melanie Gubbels Bupp; Todd N Eagar; Qizhi Tang; Helene Bour-Jordan; Hideo Yagita; Miyuki Azuma; Mohamed H Sayegh; Jeffrey A Bluestone
Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.
The Journal of experimental medicine 2006;203(12):2737-47.
2006: Hiroyuki Nakashima; Takuo Inui; Yoshiko Habu; Manabu Kinoshita; Shigeaki Nagao; Atsushi Kawaguchi; Soichiro Miura; Nariyoshi Shinomiya; Hideo Yagita; Shuhji Seki
Activation of mouse natural killer T cells accelerates liver regeneration after partial hepatectomy.
Gastroenterology 2006;131(5):1573-83.
2006: Koichi Kamata; Seiji Kamijo; Atsuo Nakajima; Akemi Koyanagi; Hisashi Kurosawa; Hideo Yagita; Ko Okumura
Involvement of TNF-like weak inducer of apoptosis in the pathogenesis of collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):6433-9.
2006: Junko Hori; Mingcong Wang; Megumi Miyashita; Keiko Tanemoto; Hiroshi Takahashi; Toshitada Takemori; Ko Okumura; Hideo Yagita; Miyuki Azuma
B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):5928-35.
2006: Yoshihiko Usui; Hisaya Akiba; Masaru Takeuchi; Takeshi Kezuka; Aya Takeuchi; Takaaki Hattori; Yoko Okunuki; Yamazaki Tomohide; Hideo Yagita; Masahiko Usui; Ko Okumura
The role of the ICOS/B7RP-1 T cell costimulatory pathway in murine experimental autoimmune uveoretinitis.
European journal of immunology 2006;36(11):3071-81.
2006: Katherine Baran; Annette Ciccone; Christoph Peters; Hideo Yagita; Phillip I Bird; Jose A Villadangos; Joseph A Trapani
Cytotoxic T lymphocytes from cathepsin B-deficient mice survive normally in vitro and in vivo after encountering and killing target cells.
The Journal of biological chemistry 2006;281(41):30485-91.
2006: Tsunekazu Oikawa; Yosuke Kamimura; Hisaya Akiba; Hideo Yagita; Ko Okumura; Hiroki Takahashi; Mikio Zeniya; Hisao Tajiri; Miyuki Azuma
Preferential involvement of Tim-3 in the regulation of hepatic CD8+ T cells in murine acute graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4281-7.
2006: Matthias Matter; Bernhard Odermatt; Hideo Yagita; Jean-Marc Nuoffer; Adrian F Ochsenbein
Elimination of chronic viral infection by blocking CD27 signaling.
The Journal of experimental medicine 2006;203(9):2145-55.
2006: Seiji Kamijo; Atsuo Nakajima; Kaori Ikeda; Kazuhiro Aoki; Keiichi Ohya; Hisaya Akiba; Hideo Yagita; Ko Okumura
Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody.
Biochemical and biophysical research communications 2006;347(1):124-32.
2006: Atsuki Fukushima; Tomoko Yamaguchi; M Azuma; Hideo Yagita; Hiasyuki Ueno
Involvement of programmed death-ligand 2 (PD-L2) in the development of experimental allergic conjunctivitis in mice.
The British journal of ophthalmology 2006;90(8):1040-5.
2006: Takanori Kanai; Koji Uraushihara; Teruji Totsuka; Yasuhiro Nemoto; Rei Fujii; Takahiro Kawamura; Shin Makita; Daisuke Sawada; Hideo Yagita; Ko Okumura; Mamoru Watanabe
Ameliorating effect of saporin-conjugated anti-CD11b monoclonal antibody in a murine T-cell-mediated chronic colitis.
Journal of gastroenterology and hepatology 2006;21(7):1136-42.
2006: Tomoyasu Uno; Kazuyoshi Takeda; Yuko Kojima; Hirohisa Yoshizawa; Hisaya Akiba; Robert S Mittler; Fumitake Gejyo; Ko Okumura; Hideo Yagita; Mark J Smyth
Eradication of established tumors in mice by a combination antibody-based therapy.
Nature medicine 2006;12(6):693-8.
2006: Mark J Smyth; Yoshihiro Hayakawa; Erika Cretney; Nadeen Zerafa; Pallavur V Sivakumar; Hideo Yagita; Kazuyoshi Takeda
IL-21 enhances tumor-specific CTL induction by anti-DR5 antibody therapy.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(10):6347-55.
2006: Britte C Beaudette-Zlatanova; Barbara J Whalen; Danny Zipris; Hideo Yagita; Jan Rozing; Herman Groen; C D Benjamin; T Hunig; Hemmo Drexhage; Mohammed Javeed I Ansari; Jean Leif; John P Mordes; Dale L Greiner; Mohamed H Sayegh; Aldo A Rossini
Costimulation and autoimmune diabetes in BB rats.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2006;6(5 Pt 1):894-902.
2006: Kyung-Mi Lee; John P Forman; Megan E McNerney; Susan E Stepp; Sumalatha Kuppireddi; Dustin Guzior; Yvette E Latchman; Mohamed H Sayegh; Hideo Yagita; Chul-Kyu Park; Seog Bae Oh; Christoph Wülfing; John Schatzle; Porunelloor A Mathew; Arlene H Sharpe; Vinay Kumar
Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions.
Blood 2006;107(8):3181-8.
2006: Bing Zhu; Indira Guleria; Arezou Khosroshahi; Tanuja Chitnis; Jaime Imitola; Miyuki Azuma; Hideo Yagita; Mohamed H Sayegh; Samia J Khoury
Differential role of programmed death-ligand 1 [corrected] and programmed death-ligand 2 [corrected] in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3480-9.
2006: Iain A M MacPhee; Hideo Yagita; D B G Oliveira
Blockade of OX40-ligand after initial triggering of the T helper 2 response inhibits mercuric chloride-induced autoimmunity.
Immunology 2006;117(3):402-8.
2006: Su K Seo; Hyoun-Mi Seo; Hye-Young Jeong; Il-Whan Choi; Yeong-Min Park; Hideo Yagita; Lipieng Chen; In-Hak Choi
Co-inhibitory role of T-cell-associated B7-H1 and B7-DC in the T-cell immune response.
Immunology letters 2006;102(2):222-8.
2006: Ana C Abadía-Molina; Honbing Ji; William A Faubion; Aimee Julien; Yvette Latchman; Hideo Yagita; Arlene Sharpe; Atul K Bhan; Cox Terhorst
CD48 controls T-cell and antigen-presenting cell functions in experimental colitis.
Gastroenterology 2006;130(2):424-34.
2006: Takatoshi Chinen; Takashi Kobayashi; Hisanobu Ogata; Giichi Takaesu; Hiromi Takaki; Masayuki Hashimoto; Hideo Yagita; Hajime Nawata; Akihiko Yoshimura
Suppressor of cytokine signaling-1 regulates inflammatory bowel disease in which both IFNgamma and IL-4 are involved.
Gastroenterology 2006;130(2):373-88.
2006: Julien Taieb; Nathalie Chaput; Cédric Ménard; Lionel Apetoh; Evelyn Ullrich; Mathieu Bonmort; Marie Péquignot; Noelia Casares; Magali Terme; Caroline Flament; Paule Opolon; Yann Lecluse; Didier Métivier; Elena Tomasello; Eric Vivier; François Ghiringhelli; François Martin; David Klatzmann; Thierry Poynard; Thomas Tursz; Graça Raposo; Hideo Yagita; Bernard Ryffel; Guido Kroemer; Laurence Zitvogel
A novel dendritic cell subset involved in tumor immunosurveillance.
Nature medicine 2006;12(2):214-9.
2006: Atsuki Fukushima; Tomoko Yamaguchi; Waka Ishida; Kazuyo Fukata; Hideo Yagita; Hisayuki Ueno
Roles of OX40 in the development of murine experimental allergic conjunctivitis: exacerbation and attenuation by stimulation and blocking of OX40.
Investigative ophthalmology & visual science 2006;47(2):657-63.
2006: Minh Diem Vu; Michael R Clarkson; Hideo Yagita; Laurence A Turka; Mohamed H Sayegh; Xian Chang Li
Critical, but conditional, role of OX40 in memory T cell-mediated rejection.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1394-401.
2006: Erika Cretney; Anil Shanker; Hideo Yagita; Mark J Smyth; Thomas J Sayers
TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer.
Immunology and cell biology 2006;84(1):87-98.
2006: Hanlu Ding; Xiongfei Wu; Jun Wu; Hideo Yagita; Yani He; Jianguo Zhang; Jiangwen Ren; Wenda Gao
Delivering PD-1 inhibitory signal concomitant with blocking ICOS co-stimulation suppresses lupus-like syndrome in autoimmune BXSB mice.
Clinical immunology (Orlando, Fla.) 2006;118(2-3):258-67.
2006: Takashi Ando; Jiro Ichikawa; Masanori Wako; Kyosuke Hatsushika; Yoshiyuki Watanabe; Michitomo Sakuma; Kachio Tasaka; Hideoki Ogawa; Yoshiki Hamada; Hideo Yagita; Atsuhito Nakao
TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells.
Arthritis research & therapy 2006;8(5):R146.
2006: Senji Tafuku; Takehiro Matsuda; Hirochika Kawakami; Mariko Tomita; Hideo Yagita; Naoki Mori
Potential mechanism of resistance to TRAIL-induced apoptosis in Burkitt's lymphoma.
European journal of haematology 2006;76(1):64-74.
2006: Adam T C Cheuk; Lucas Chan; Barbara Czepulkowski; Stuart A Berger; Hideo Yagita; Ko Okumura; Farzin Farzaneh; Ghulam J Mufti; Barbara Guinn
Development of a whole cell vaccine for acute myeloid leukaemia.
Cancer immunology, immunotherapy : CII 2006;55(1):68-75.
2005: Atsuki Fukushima; Tomoko Yamaguchi; Waka Ishida; Kazuyo Fukata; Hideo Yagita; Hisayuki Ueno
The interaction between ICOS and B7RP-1 is not required for the development of experimental murine allergic conjunctivitis.
Biochemical and biophysical research communications 2005;338(4):1726-31.
2005: Petra Baumann; Natascha Cremers; Frans Kroese; Gertraud Orend; Ruth Chiquet-Ehrismann; Toshi Uede; Hideo Yagita; Jonathan P Sleeman
CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis.
Cancer research 2005;65(23):10783-93.
2005: Begonia Ruiz-Perez; Doo Ryeon Chung; Arlene H Sharpe; Hideo Yagita; Wiltrud M Kalka-Moll; Mohamed H Sayegh; Dennis L Kasper; Arthur O Tzianabos
Modulation of surgical fibrosis by microbial zwitterionic polysaccharides.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(46):16753-8.
2005: Jean-Philippe Herbeuval; Jean-Charles Grivel; Adriano Boasso; Andrew W Hardy; Claire Chougnet; Matthew J Dolan; Hideo Yagita; Jeffrey D Lifson; Gene M Shearer
CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis.
Blood 2005;106(10):3524-31.
2005: Yasushi Miyahira; Yasuhiro Takashima; Seiki Kobayashi; Yasunobu Matsumoto; Tsutomu Takeuchi; Mutsuko Ohyanagi-Hara; Ayako Yoshida; Akihiko Ohwada; Hisaya Akiba; Hideo Yagita; Ko Okumura; Hideoki Ogawa
Immune responses against a single CD8+-T-cell epitope induced by virus vector vaccination can successfully control Trypanosoma cruzi infection.
Infection and immunity 2005;73(11):7356-65.
2005: Matthias Matter; Sabine Mumprecht; Daniel D Pinschewer; Viktor Pavelic; Hideo Yagita; Stefan Krautwald; Jannie Borst; Adrian F Ochsenbein
Virus-induced polyclonal B cell activation improves protective CTL memory via retained CD27 expression on memory CTL.
European journal of immunology 2005;35(11):3229-39.
2005: Atsuki Fukushima; Tomoko Yamaguchi; Waka Ishida; Kazuyo Fukata; Robert S Mittler; Hideo Yagita; Hisayuki Ueno
Engagement of 4-1BB inhibits the development of experimental allergic conjunctivitis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(8):4897-903.
2005: Xin Xue; Jiang-Hu Piao; Akihito Nakajima; Sachiko Sakon-Komazawa; Yuko Kojima; Kazutoshi Mori; Hideo Yagita; Ko Okumura; Heather Harding; Hiroyasu Nakano
Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha.
The Journal of biological chemistry 2005;280(40):33917-25.
2005: Erika Cretney; Jonathan L McQualter; Nobuhiko Kayagaki; Hideo Yagita; Claude C A Bernard; Iqbal Grewal; Avi Ashkenazi; Mark J Smyth
TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L suppresses experimental autoimmune encephalomyelitis in mice.
Immunology and cell biology 2005;83(5):511-9.
2005: Hisaya Akiba; Kazuyoshi Takeda; Yuko Kojima; Yoshihiko Usui; Norihiro Harada; Yamazaki Tomohide; Juan Ma; Katsunari Tezuka; Hideo Yagita; Ko Okumura
The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2340-8.
2005: Zachary Zimmerman; Alwi M Shatry; Vadim Deyev; Eckhard R Podack; Michele Mammolenti; Bruce R Blazar; Hideo Yagita; Robert B Levy
Effector cells derived from host CD8 memory T cells mediate rapid resistance against minor histocompatibility antigen-mismatched allogeneic marrow grafts without participation of perforin, Fas ligand, and the simultaneous inhibition of 3 tumor necrosis factor family effector pathways.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(8):576-86.
2005: Yamazaki Tomohide; Hisaya Akiba; Akemi Koyanagi; Miyuki Azuma; Hideo Yagita; Ko Okumura
Blockade of B7-H1 on macrophages suppresses CD4+ T cell proliferation by augmenting IFN-gamma-induced nitric oxide production.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1586-92.
2005: Hiroki Kawamura; Hideo Yagita; Tetsuro Nisizawa; Nakako Izumi; Chikako Miyaji; Russell E Vance; David H Raulet; Ko Okumura; Toru Abo
Amelioration of acute graft-versus-host disease by NKG2A engagement on donor T cells.
European journal of immunology 2005;35(8):2358-66.
2005: Indira Guleria; Arezou Khosroshahi; Mohammed Javeed I Ansari; Antje Habicht; Miyuki Azuma; Hideo Yagita; Randolph J Noelle; Anthony J Coyle; Andrew L Mellor; Samia J Khoury; Mohamed H Sayegh
A critical role for the programmed death ligand 1 in fetomaternal tolerance.
The Journal of experimental medicine 2005;202(2):231-7.
2005: Keiichi Hara; Mayumi Okamoto; Toshihiko Aki; Hideo Yagita; Hirotoshi Tanaka; Yoichi Mizukami; Hiroshi Nakamura; Akio Tomoda; Naotaka Hamasaki; Dongchon Kang
Synergistic enhancement of TRAIL- and tumor necrosis factor alpha-induced cell death by a phenoxazine derivative.
Molecular cancer therapeutics 2005;4(7):1121-7.
2005: Hisashi Bashuda; Masaaki Kimikawa; Kenichiro Seino; Yojiro Kato; Fumiko Ono; Akira Shimizu; Hideo Yagita; Satoshi Teraoka; Ko Okumura
Renal allograft rejection is prevented by adoptive transfer of anergic T cells in nonhuman primates.
The Journal of clinical investigation 2005;115(7):1896-902.
2005: Tsuyoshi Ota; Kazuyoshi Takeda; Hisaya Akiba; Yoshihiro Hayakawa; Kouetsu Ogasawara; Yoshinori Ikarashi; Sachiko Miyake; Hiro Wakasugi; Takashi Yamamura; Mitchell Kronenberg; David H Raulet; Katsuyuki Kinoshita; Hideo Yagita; Mark J Smyth; Ko Okumura
IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2.
Blood 2005;106(1):184-92.
2005: Toshitaka Tanaka; Tomohiko Ebata; Atsushi Tajima; Katsuyuki Kinoshita; Ko Okumura; Hideo Yagita
Beta2-microglobulin required for cell surface expression of blastocyst MHC.
Biochemical and biophysical research communications 2005;332(1):311-7.
2005: Mark J Smyth; Morgan E Wallace; Stephen L Nutt; Hideo Yagita; Dale I Godfrey; Yoshihiro Hayakawa
Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer.
The Journal of experimental medicine 2005;201(12):1973-85.
2005: Yuki Kaduka; Kazuyoshi Takeda; Masafumi Nakayama; Katsuyuki Kinoshita; Hideo Yagita; Ko Okumura
TWEAK mediates anti-tumor effect of tumor-infiltrating macrophage.
Biochemical and biophysical research communications 2005;331(2):384-90.
2005: Shizue Tani-Ichi; Koji Maruyama; Nami Kondo; Masakazu Nagafuku; Kazuya Kabayama; Jin-ichi Inokuchi; Yukiko Shimada; Yoshiko Ohno-Iwashita; Hideo Yagita; Sunao Kawano; Atsushi Kosugi
Structure and function of lipid rafts in human activated T cells.
International immunology 2005;17(6):749-58.
2005: Toshiro Ito; Takuya Ueno; Michael R Clarkson; Xueli Yuan; Mollie Jurewicz; Hideo Yagita; Miyuki Azuma; Arlene H Sharpe; Hugh Auchincloss; Mohamed H Sayegh; Nader Najafian
Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):6648-56.
2005: Teruji Totsuka; Takanori Kanai; Shin Makita; Rei Fujii; Yasuhiro Nemoto; Shigeru Oshima; Ryuichi Okamoto; Akemi Koyanagi; Hisaya Akiba; Ko Okumura; Hideo Yagita; Mamoru Watanabe
Regulation of murine chronic colitis by CD4+CD25- programmed death-1+ T cells.
European journal of immunology 2005;35(6):1773-85.
2005: Hisanori Kashizuka; Masayuki Sho; Takeo Nomi; Naoya Ikeda; Yukiyasu Kuzumoto; Satoru Akashi; Yoshikazu Tsurui; Takashi Mizuno; Hiromichi Kanehiro; Hideo Yagita; Yoshiyuki Nakajima; Mohamed H Sayegh
Role of the ICOS-B7h costimulatory pathway in the pathophysiology of chronic allograft rejection.
Transplantation 2005;79(9):1045-50.
2005: Osamu Aramaki; Fumihiko Inoue; Tadatoshi Takayama; Motohide Shimazu; Masaki Kitajima; Yoshifumi Ikeda; Ko Okumura; Hideo Yagita; Nozomu Shirasugi; Masanori Niimi
Various costimulatory pathways are essential for induction of regulatory cells by intratracheal delivery of alloantigen.
Transplantation proceedings 2005;37(4):1934-6.
2005: Rintaroh Tsukahara; Masaru Takeuchi; Hisaya Akiba; Takeshi Kezuka; Kazuyoshi Takeda; Yoshihiko Usui; Masahiko Usui; Hideo Yagita; Ko Okumura
Critical contribution of CD80 and CD86 to induction of anterior chamber-associated immune deviation.
International immunology 2005;17(5):523-30.
2005: Yuichiro Ohigashi; Masayuki Sho; Yukishige Yamada; Yoshikazu Tsurui; Kaoru Hamada; Naoya Ikeda; Takashi Mizuno; Ryo Yoriki; Hisanori Kashizuka; Katsunari Yane; Fumihiko Tsushima; Noriko Otsuki; Hideo Yagita; Miyuki Azuma; Yoshiyuki Nakajima
Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(8):2947-53.
2005: Ruping Shao; Dung-Fang Lee; Yong Wen; Yi Ding; Weiya Xia; Bo Ping; Hideo Yagita; Bill Spohn; Mien-Chie Hung
E1A sensitizes cancer cells to TRAIL-induced apoptosis through enhancement of caspase activation.
Molecular cancer research : MCR 2005;3(4):219-26.
2005: Takehiro Matsuda; alex almasan; Mariko Tomita; Kazumi Tamaki; Mika Saito; Masayuki Tadano; Hideo Yagita; Takao Ohta; Naoki Mori
Dengue virus-induced apoptosis in hepatic cells is partly mediated by Apo2 ligand/tumour necrosis factor-related apoptosis-inducing ligand.
The Journal of general virology 2005;86(Pt 4):1055-65.
2005: Katsuaki Sato; Takashi Nakaoka; Naohide Yamashita; Hideo Yagita; Hiroshi Kawasaki; Chikao Morimoto; Masanori Baba; Takami Matsuyama
TRAIL-transduced dendritic cells protect mice from acute graft-versus-host disease and leukemia relapse.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):4025-33.
2005: Osamu Aramaki; Fumihiko Inoue; Tadatoshi Takayama; Motohide Shimazu; Masaki Kitajima; Yoshifumi Ikeda; Ko Okumura; Hideo Yagita; Nozomu Shirasugi; Masanori Niimi
Interleukin-10 but not transforming growth factor-beta is essential for generation and suppressor function of regulatory cells induced by intratracheal delivery of alloantigen.
Transplantation 2005;79(5):568-76.
2005: Sigrid E Sandner; Michael R Clarkson; Alan D Salama; Alberto Sanchez-Fueyo; Christoph Domenig; Antje Habicht; Nader Najafian; Hideo Yagita; Miyuki Azuma; Laurence A Turka; Mohamed H Sayegh
Role of the programmed death-1 pathway in regulation of alloimmune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3408-15.
2005: Kazuyoshi Takeda; Erika Cretney; Yoshihiro Hayakawa; Tsuyoshi Ota; Hisaya Akiba; Kouetsu Ogasawara; Hideo Yagita; Katsuyuki Kinoshita; Ko Okumura; Mark J Smyth
TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver.
Blood 2005;105(5):2082-9.
2005: Hiroshi Kaneda; Kazuyoshi Takeda; Tsuyoshi Ota; Yuki Kaduka; Hisaya Akiba; Yoshinori Ikarashi; Hiro Wakasugi; Mitchell Kronenberg; Katsuyuki Kinoshita; Hideo Yagita; Ko Okumura
ICOS costimulates invariant NKT cell activation.
Biochemical and biophysical research communications 2005;327(1):201-7.
2005: Akira Yamada; Alan D Salama; Masayuki Sho; Nader Najafian; Toshiro Ito; John P Forman; Reshma Kewalramani; Sigrid E Sandner; Hiroshi Harada; Michael R Clarkson; Didier A Mandelbrot; Arlene H Sharpe; Hideo Oshima; Hideo Yagita; Geetha Chalasani; Fadi G Lakkis; Hugh Auchincloss; Mohamed H Sayegh
CD70 signaling is critical for CD28-independent CD8+ T cell-mediated alloimmune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1357-64.
2005: Takehiro Matsuda; alex almasan; Mariko Tomita; Jun-Nosuke Uchihara; Masato Masuda; Kazuiku Ohshiro; Nobuyuki Takasu; Hideo Yagita; Takao Ohta; Naoki Mori
Resistance to Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis and constitutive expression of Apo2L/TRAIL in human T-cell leukemia virus type 1-infected T-cell lines.
Journal of virology 2005;79(3):1367-78.
2005: Mark J Smyth; Erika Cretney; Janice M Kelly; Jennifer A Westwood; Shayna E A Street; Hideo Yagita; Kazuyoshi Takeda; Serani L H van Dommelen; Mariapia A Degli-Esposti; Yoshihiro Hayakawa
Activation of NK cell cytotoxicity.
Molecular immunology 2005;42(4):501-10.
2005: Timothy N J Bullock; Hideo Yagita
Induction of CD70 on dendritic cells through CD40 or TLR stimulation contributes to the development of CD8+ T cell responses in the absence of CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(2):710-7.
2005: Sigrid E Sandner; Michael R Clarkson; Alan D Salama; Alberto Sanchez-Fueyo; Hideo Yagita; Laurence A Turka; Mohamed H Sayegh
Mechanisms of tolerance induced by donor-specific transfusion and ICOS-B7h blockade in a model of CD4+ T-cell-mediated allograft rejection.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(1):31-9.
2004: Katrin U Lundin; Valentina Screpanti; Hilde Omholt; Peter O Hofgaard; Hideo Yagita; Alf Grandien; Bjarne Bogen
CD4+ T cells kill Id+ B-lymphoma cells: FasLigand-Fas interaction is dominant in vitro but is redundant in vivo.
Cancer immunology, immunotherapy : CII 2004;53(12):1135-45.
2004: Tameyoshi Yamamoto; Hiroaki Nagano; Masato Sakon; Hiroshi Wada; Hidetoshi Eguchi; Motoi Kondo; Bazarragchaa Damdinsuren; Hideo Ota; Masato Nakamura; Hisashi Wada; Shigeru Marubashi; Atsushi Miyamoto; Keizo Dono; Koji Umeshita; Shoji Nakamori; Hideo Yagita; Morito Monden
Partial contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/TRAIL receptor pathway to antitumor effects of interferon-alpha/5-fluorouracil against Hepatocellular Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(23):7884-95.
2004: Chiharu Nishiyama; Yushiro Akizawa; Makoto Nishiyama; Tomoko Tokura; Hiroshi Kawada; Kouichi Mitsuishi; Masanari Hasegawa; Tomonobu Ito; Nobuhiro Nakano; Atsushi Okamoto; Atsushi Takagi; Hideo Yagita; Ko Okumura; Hideoki Ogawa
Polymorphisms in the Fc epsilon RI beta promoter region affecting transcription activity: a possible promoter-dependent mechanism for association between Fc epsilon RI beta and atopy.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6458-64.
2004: Manuela Flórido; Margarida Borges; Hideo Yagita; Rui Appelberg
Contribution of CD30/CD153 but not of CD27/CD70, CD134/OX40L, or CD137/4-1BBL to the optimal induction of protective immunity to Mycobacterium avium.
Journal of leukocyte biology 2004;76(5):1039-46.
2004: Akemi Ozaki; Atsuki Fukushima; Waka Ishida; Olga Zinchuk; Kazuyo Fukata; Yoshihiro Hayashi; Hideaki Enzan; Masaru Takata; Hideo Yagita; Hisayuki Ueno
Analysis of Ag-presenting cells in the conjunctiva during the development of experimental immune-mediated blepharoconjunctivitis.
Current eye research 2004;29(4-5):277-86.
2004: Chinatsu Kasuga; Tomohiko Ebata; Nobuhiko Kayagaki; Hideo Yagita; Makoto Hishii; Hajime Arai; Kiyoshi Sato; Ko Okumura
Sensitization of human glioblastomas to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by NF-kappaB inhibitors.
Cancer science 2004;95(10):840-4.
2004: Hideo Yagita; Kazuyoshi Takeda; Yoshihiro Hayakawa; Mark J Smyth; Ko Okumura
TRAIL and its receptors as targets for cancer therapy.
Cancer science 2004;95(10):777-83.
2004: Hongyan Diao; Shigeyuki Kon; Kazuya Iwabuchi; Chiemi Kimura; Junko Morimoto; Daisuke Ito; Tatsuya Segawa; Masahiro Maeda; Junji Hamuro; Toshinori Nakayama; Masaru Taniguchi; Hideo Yagita; Luc Van Kaer; Kazunori Onóe; David T Denhardt; Susan R Rittling; Toshimitsu Uede
Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases.
Immunity 2004;21(4):539-50.
2004: Jun-Li Luo; Shin Maeda; Li-Chung Hsu; Hideo Yagita; Michael Karin
Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression.
Cancer cell 2004;6(3):297-305.
2004: Kiyoko Izawa; Kenzaburo Tani; Yukoh Nakazaki; Hitoshi Hibino; Hajime Sugiyama; Akemi Kawasaki; Erika Sasaki; Chieko Nishioka; Hajime Ishii; Yasushi Soda; Hideo Yagita; Yoshikuni Tanioka; Arinobu Tojo; Shigetaka Asano
Hematopoietic activity of common marmoset CD34 cells isolated by a novel monoclonal antibody MA24.
Experimental hematology 2004;32(9):843-51.
2004: Bruce R Blazar; Robert B Levy; Tak W Mak; Angela Panoskaltsis-Mortari; Hiromi Muta; Monica Jones; Melinda Roskos; Jonathan S Serody; Hideo Yagita; Eckhard R Podack; Patricia A Taylor
CD30/CD30 ligand (CD153) interaction regulates CD4+ T cell-mediated graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):2933-41.
2004: Hong Rae Cho; Byungsuk Kwon; Hideo Yagita; Soojin La; Eun-A Lee; Jeong-Eun Kim; H Akiba; Juyang Kim; Jae-Hee Suh; Dass S Vinay; Seong-A Ju; Byung-Sam Kim; Robert S Mittler; K Okumura; Byoung S Kwon
Blockade of 4-1BB (CD137)/4-1BB ligand interactions increases allograft survival.
Transplant international : official journal of the European Society for Organ Transplantation 2004;17(7):351-61.
2004: Tomonari Sasazuki; Tatsuma Okazaki; Kurisu Tada; Sachiko Sakon-Komazawa; Mitsuo Katano; Masao Tanaka; Hideo Yagita; Ko Okumura; Naoko Tominaga; Yoshihide Hayashizaki; Yasushi Okazaki; Hiroyasu Nakano
Genome wide analysis of TNF-inducible genes reveals that antioxidant enzymes are induced by TNF and responsible for elimination of ROS.
Molecular immunology 2004;41(5):547-51.
2004: Masatoshi Suzui; Takeshi Kawai; Hiroko Kimura; Kazuyoshi Takeda; Hideo Yagita; Ko Okumura; Pang N Shek; Roy J Shephard
Natural killer cell lytic activity and CD56(dim) and CD56(bright) cell distributions during and after intensive training.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;96(6):2167-73.
2004: Hongri Xu; Atsushi Okamoto; Jiro Ichikawa; Takashi Ando; Kachio Tasaka; Keisuke Masuyama; Hideoki Ogawa; Hideo Yagita; Ko Okumura; Atsuhito Nakao
TWEAK/Fn14 interaction stimulates human bronchial epithelial cells to produce IL-8 and GM-CSF.
Biochemical and biophysical research communications 2004;318(2):422-7.
2004: Zhenyue Hao; Brigitte Hampel; Hideo Yagita; Klaus Rajewsky
T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
The Journal of experimental medicine 2004;199(10):1355-65.
2004: Long Jin; Atsuhito Nakao; Masafumi Nakayama; Noriko Yamaguchi; Yuko Kojima; Nobuhiro Nakano; Ryoji Tsuboi; Ko Okumura; Hideo Yagita; Hideoki Ogawa
Induction of RANTES by TWEAK/Fn14 interaction in human keratinocytes.
The Journal of investigative dermatology 2004;122(5):1175-9.
2004: Matthew A Holsti; Tanuja Chitnis; Ronald J Panzo; Roderick T Bronson; Hideo Yagita; Mohamed H Sayegh; Arthur O Tzianabos
Regulation of postsurgical fibrosis by the programmed death-1 inhibitory pathway.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(9):5774-81.
2004: Akihiro Hasegawa; Xin Cheng; Kiichi Kajino; Alan Berezov; Kaoru Murata; Toshinori Nakayama; Hideo Yagita; Ramachandran Murali; Mark I Greene
Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(17):6599-604.
2004: Masako Kohyama; Daisuke Sugahara; Shigeru Sugiyama; Hideo Yagita; Ko Okumura; Nobumichi Hozumi
Inducible costimulator-dependent IL-10 production by regulatory T cells specific for self-antigen.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(12):4192-7.
2004: Shayna E A Street; Yoshihiro Hayakawa; Yifan Zhan; Andrew M Lew; Duncan MacGregor; Amanda M Jamieson; Andreas Diefenbach; Hideo Yagita; Dale I Godfrey; Mark J Smyth
Innate immune surveillance of spontaneous B cell lymphomas by natural killer cells and gammadelta T cells.
The Journal of experimental medicine 2004;199(6):879-84.
2004: Kazuyoshi Takeda; Noriko Yamaguchi; Hisaya Akiba; Yuko Kojima; Yoshihiro Hayakawa; Jane E Tanner; Thomas J Sayers; Naoko Seki; Ko Okumura; Hideo Yagita; Mark J Smyth
Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.
The Journal of experimental medicine 2004;199(4):437-48.
2004: Koichiro Matsumoto; Hiromasa Inoue; Takako Nakano; Miyuki Tsuda; Yuki Yoshiura; Satoru Fukuyama; Fumihiko Tsushima; Tomoaki Hoshino; Hisamichi Aizawa; Hisaya Akiba; Drew M Pardoll; Nobuyuki Hara; Hideo Yagita; Miyuki Azuma; Yoichi Nakanishi
B7-DC regulates asthmatic response by an IFN-gamma-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2530-41.
2004: Miriam Lichtner; Concepción Marañón; Pierre-Olivier Vidalain; Olga Azocar; Daniel Hanau; Pierre Lebon; Marianne Burgard; Christine Rouzioux; Vincenzo Vullo; Hideo Yagita; Chantal Rabourdin-Combe; Christine Servet; Anne Hosmalin
HIV type 1-infected dendritic cells induce apoptotic death in infected and uninfected primary CD4 T lymphocytes.
AIDS research and human retroviruses 2004;20(2):175-82.
2004: Gülçin Demirci; Farhana Amanullah; Reshma Kewalaramani; Hideo Yagita; Terry B Strom; Mohamed H Sayegh; Xian Chang Li
Critical role of OX40 in CD28 and CD154-independent rejection.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1691-8.
2004: Osamu Aramaki; Nozomu Shirasugi; Tadatoshi Takayama; Motohide Shimazu; Masaki Kitajima; Yoshifumi Ikeda; Miyuki Azuma; Ko Okumura; Hideo Yagita; Masanori Niimi
Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen.
Transplantation 2004;77(1):6-12.
2004: Yoshinori Seko; Kazuyuki Sugishita; Osamu Sato; Atsuhiko Takagi; Yusuke Tada; Hiroshi Matsuo; Hideo Yagita; Ko Okumura; Ryozo Nagai
Expression of costimulatory molecules (4-1BBL and Fas) and major histocompatibility class I chain-related A (MICA) in aortic tissue with Takayasu's arteritis.
Journal of vascular research 2004;41(1):84-90.
2004: Yoshihiro Hayakawa; Valentina Screpanti; Hideo Yagita; Alf Grandien; Hans-Gustaf Ljunggren; Mark J Smyth; Benedict J Chambers
NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):123-9.
2003: Yasushi Miyahira; Hisaya Akiba; Masaharu Katae; Kaori Kubota; Seiki Kobayashi; Tsutomu Takeuchi; Adolfo García-Sastre; Yoshinosuke Fukuchi; Ko Okumura; Hideo Yagita; Takashi Aoki
Cutting edge: a potent adjuvant effect of ligand to receptor activator of NF-kappa B gene for inducing antigen-specific CD8+ T cell response by DNA and viral vector vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6344-8.
2003: Taisuke Ito; Naohiro Seo; Hideo Yagita; Kunio Tsujimura; Masahiro Takigawa; Yoshiki Tokura
Alterations of immune functions in barrier disrupted skin by UVB irradiation.
Journal of dermatological science 2003;33(3):151-9.
2003: Yuichi Matsui; Akio Saiura; Yasuhiko Sugawara; Masataka Sata; Katsutoshi Naruse; Hideo Yagita; Kohro Takahide; Chikage Mataki; Akashi Izumi; Takuhiro Yamaguchi; Takashi Minami; Toshiko Sakihama; Sayoko Ihara; Hiroyuki Aburatani; Takao Hamakubo; Tatsuhiko Kodama; Makuuchi Masatoshi
Identification of gene expression profile in tolerizing murine cardiac allograft by costimulatory blockade.
Physiological genomics 2003;15(3):199-208.
2003: Yasushi Miyahira; Hisaya Akiba; Shu-Hei Ogawa; Tomohiro Ishi; Shiho Watanabe; Seiki Kobayashi; Tsutomu Takeuchi; Takashi Aoki; Katsunari Tezuka; Ryo Abe; Ko Okumura; Hideo Yagita; Naohiro Watanabe
Involvement of ICOS-B7RP-1 costimulatory pathway in the regulation of immune responses to Leishmania major and Nippostrongylus brasiliensis infections.
Immunology letters 2003;89(2-3):193-9.
2003: Takanori Kanai; Teruji Totsuka; Koji Uraushihara; Shin Makita; Tetsuya Nakamura; Kazutaka Koganei; Tsuneo Fukushima; Hisaya Akiba; Hideo Yagita; Ko Okumura; Utako Machida; Hideyuki Iwai; Miyuki Azuma; Lieping Chen; Mamoru Watanabe
Blockade of B7-H1 suppresses the development of chronic intestinal inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(8):4156-63.
2003: Fumihiko Tsushima; Hideyuki Iwai; Noriko Otsuki; Masaaki Abe; Sachiko Hirose; Yamazaki Tomohide; Hisaya Akiba; Hideo Yagita; Yuzo Takahashi; Ken Omura; Ko Okumura; Miyuki Azuma
Preferential contribution of B7-H1 to programmed death-1-mediated regulation of hapten-specific allergic inflammatory responses.
European journal of immunology 2003;33(10):2773-82.
2003: N Dan; Takanori Kanai; Teruji Totsuka; Ryoichi Iiyama; Motomi Yamazaki; Tokihiko Sawada; Tatsuya Miyata; Hideo Yagita; Ko Okumura; Masahiko Watanabe
Ameliorating effect of anti-Fas ligand MAb on wasting disease in murine model of chronic colitis.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(4):G754-60.
2003: Tatsuya Saitoh; Masafumi Nakayama; Hiroyasu Nakano; Hideo Yagita; Naoki Yamamoto; Shoji Yamaoka
TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.
The Journal of biological chemistry 2003;278(38):36005-12.
2003: Osamu Aramaki; Nozomu Shirasugi; Yoshinobu Akiyama; Shintaro Shibutani; Tadatoshi Takayama; Motohide Shimazu; Masaki Kitajima; Yoshifumi Ikeda; Ko Okumura; Hideo Yagita; Masanori Niimi
CD27/CD70, CD134/CD134 ligand, and CD30/CD153 pathways are independently essential for generation of regulatory cells after intratracheal delivery of alloantigen.
Transplantation 2003;76(5):772-6.
2003: Hideyuki Iwai; Masaaki Abe; Sachiko Hirose; Fumihiko Tsushima; Katsunari Tezuka; Hisaya Akiba; Hideo Yagita; Ko Okumura; Hitoshi Kohsaka; Nobuyuki Miyasaka; Miyuki Azuma
Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):2848-54.
2003: Hideki Tsuji; Satoshi Kawaguchi; Takuro Wada; Satoshi Nagoya; Manabu Inobe; Hideo Yagita; Ko Okumura; Toshihiko Yamashita; Toshimitsu Uede
Concurrent induction of T-cell activation and apoptosis of osteosarcoma cells by adenovirus-mediated B7-1/Fas chimeric gene transfer.
Cancer gene therapy 2003;10(9):717-25.
2003: Sagarika Chakrabarty; Masao Nagata; Hisafumi Yasuda; L Wen; Maki Nakayama; Shahead Ali Chowdhury; Katsumi Yamada; Zhenzi Jin; Reiko Kotani; Hiroaki Moriyama; O Shimozato; Hideo Yagita; Koichi Yokono
Critical roles of CD30/CD30L interactions in murine autoimmune diabetes.
Clinical and experimental immunology 2003;133(3):318-25.
2003: Atsushi Tajima; Toshitaka Tanaka; Tomohiko Ebata; Kazuyoshi Takeda; Akemi Kawasaki; Janice M Kelly; Phillip K Darcy; Russell E Vance; David H Raulet; Katsuyuki Kinoshita; Ko Okumura; Mark J Smyth; Hideo Yagita
Blastocyst MHC, a putative murine homologue of HLA-G, protects TAP-deficient tumor cells from natural killer cell-mediated rejection in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):1715-21.
2003: Pornpan Youngnak; Yuko Kozono; Haruo Kozono; Hideyuki Iwai; Noriko Otsuki; Hisayo Jin; Ken Omura; Hideo Yagita; Drew M Pardoll; Lieping Chen; Miyuki Azuma
Differential binding properties of B7-H1 and B7-DC to programmed death-1.
Biochemical and biophysical research communications 2003;307(3):672-7.
2003: Sachiko Sakon; Xin Xue; Mutsuhiro Takekawa; Tomonari Sasazuki; Tatsuma Okazaki; Yuko Kojima; Jian-Hu Piao; Hideo Yagita; Ko Okumura; Takahiro Doi; Hiroyasu Nakano
NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death.
The EMBO journal 2003;22(15):3898-909.
2003: Bruce R Blazar; Beatriz M Carreno; Angela Panoskaltsis-Mortari; LauraL Carter; Yoshiko Iwai; Hideo Yagita; Hiroyuki Nishimura; Patricia A Taylor
Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-gamma-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1272-7.
2003: Shahram Salek-Ardakani; Jim (Jianxun) Song; Beth S Halteman; Amha Gebre-Hiwot Jember; Hisaya Akiba; Hideo Yagita; Michael Croft
OX40 (CD134) controls memory T helper 2 cells that drive lung inflammation.
The Journal of experimental medicine 2003;198(2):315-24.
2003: Masafumi Nakayama; Norihiro Harada; Ko Okumura; Hideo Yagita
Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies.
Biochemical and biophysical research communications 2003;306(4):819-25.
2003: Alan D Salama; Tanuja Chitnis; Jaime Imitola; Mohammed Javeed I Ansari; Hisaya Akiba; Fumihiko Tushima; Miyuki Azuma; Hideo Yagita; Mohamed H Sayegh; Samia J Khoury
Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis.
The Journal of experimental medicine 2003;198(1):71-8.
2003: Mohammed Javeed I Ansari; Alan D Salama; Tanuja Chitnis; Rex Smith; Hideo Yagita; Hisaya Akiba; Yamazaki Tomohide; Miyuki Azuma; Hideyuki Iwai; Samia J Khoury; Hugh Auchincloss; Mohamed H Sayegh
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.
The Journal of experimental medicine 2003;198(1):63-9.
2003: Tae Kwang Shin; Gene Kennedy; Kevin Gorski; Haruo Tsuchiya; Haruhiko Koseki; Miyuki Azuma; Hideo Yagita; Lieping Chen; Jonathan D Powell; Drew M Pardoll; Franck Housseau
Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor.
The Journal of experimental medicine 2003;198(1):31-8.
2003: Ryoichi Iiyama; Takanori Kanai; Koji Uraushihara; Teruji Totsuka; Tetsuya Nakamura; Tatsuya Miyata; Hideo Yagita; A Kushi; K Suzuki; Katsunari Tezuka; Masahiko Watanabe
The role of inducible co-stimulator (ICOS)/B7-related protein-1 (B7RP-1) interaction in the functional development of Peyer's patches.
Immunology letters 2003;88(1):63-70.
2003: Yasuyuki Kirii; Tomomi Inoue; Kohichiro Yoshino; Nobuhiko Kayagaki; Hideo Yagita; Ko Okumura; Hiroaki Shibata; Yasuhiro Yoshikawa; Keiji Terao
Molecular cloning, functional characterization, and enzyme-linked immunosorbent assay of cynomolgus monkey Fas ligand.
Journal of immunological methods 2003;278(1-2):201-9.
2003: Hiroshi Harada; Alan D Salama; Masayuki Sho; Atsushi Izawa; Sigrid E Sandner; Toshiro Ito; Hisaya Akiba; Hideo Yagita; Arlene H Sharpe; Gordon J Freeman; Mohamed H Sayegh
The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity.
The Journal of clinical investigation 2003;112(2):234-43.
2003: Izumi Yoshizawa; Tsuguo Mizuochi; Akio Ogata; Masahiro Murakami; Hideo Yagita; Yoshimasa Takahashi; Tsuguo Mizuochi; Toshitada Takemori; Yasuko Tsunetsugu-Yokota; Hideo Yagaita
Studies on the generation and maintenance of mucosal cytotoxic T lymphocytes against human immunodeficiency virus type 1 Gag in mice.
AIDS research and human retroviruses 2003;19(6):469-79.
2003: Yasushi Miyahira; Masaharu Katae; Seiki Kobayashi; Tsutomu Takeuchi; Yoshinosuke Fukuchi; Ryo Abe; Ko Okumura; Hideo Yagita; Takashi Aoki
Critical contribution of CD28-CD80/CD86 costimulatory pathway to protection from Trypanosoma cruzi infection.
Infection and immunity 2003;71(6):3131-7.
2003: Nozomu Shirasugi; Yoshinobu Akiyama; Osamu Aramaki; Shintaro Shibutani; Kenji Matsumoto; Hisashi Bashuda; Hideo Yagita; Ko Okumura; Yoshifumi Ikeda; Masanori Niimi
Role of the CTLA4 pathway in hyporesponsiveness induced by intratracheal delivery of alloantigen.
Transplantation 2003;75(10):1636-9.
2003: Kyung-Mi Lee; Sadhna Bhawan; Takashi Majima; Hairong Wei; Michael I Nishimura; Hideo Yagita; Vinay Kumar
Cutting edge: the NK cell receptor 2B4 augments antigen-specific T cell cytotoxicity through CD48 ligation on neighboring T cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(10):4881-5.
2003: Bruce R Blazar; Arlene H Sharpe; Andy I Chen; Angela Panoskaltsis-Mortari; Christopher Lees; Hisaya Akiba; Hideo Yagita; Nigel Killeen; Patricia A Taylor
Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients.
Blood 2003;101(9):3741-8.
2003: Kanako Uno; Takeshi Inukai; Nobuhiko Kayagaki; Kumiko Goi; Hiroki Sato; Atsushi Nemoto; Kazuya Takahashi; Keiko Kagami; Noriko Yamaguchi; Hideo Yagita; Ko Okumura; Toshiko Koyama-Okazaki; Toshio Suzuki; Kanji Sugita; Shinpei Nakazawa
TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome-positive leukemia cells.
Blood 2003;101(9):3658-67.
2003: Akihiko Hoshino; Yoshitaka Tanaka; Hisaya Akiba; Yumiko Asakura; Yasuo Mita; Takanobu Sakurai; Akiko Takaoka; Shiro Nakaike; Naoto Ishii; Kazuo Sugamura; Hideo Yagita; Ko Okumura
Critical role for OX40 ligand in the development of pathogenic Th2 cells in a murine model of asthma.
European journal of immunology 2003;33(4):861-9.
2003: Teruji Totsuka; Takanori Kanai; Koji Uraushihara; Ryoichi Iiyama; Motomi Yamazaki; Hisaya Akiba; Hideo Yagita; Ko Okumura; Masahiko Watanabe
Therapeutic effect of anti-OX40L and anti-TNF-alpha MAbs in a murine model of chronic colitis.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(4):G595-603.
2003: Xueli Yuan; Alan D Salama; Victor M Dong; Isabela Schmitt; Nader Najafian; Anil Chandraker; Hisaya Akiba; Hideo Yagita; Mohamed H Sayegh
The role of the CD134-CD134 ligand costimulatory pathway in alloimmune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):2949-55.
2003: Yoshiharu Miura; Naoko Misawa; Yuji Kawano; Hiroshi Okada; Yoshio Inagaki; Naoki Yamamoto; Mamoru Ito; Hideo Yagita; Ko Okumura; Hidehiro Mizusawa; Yoshio Koyanagi
Tumor necrosis factor-related apoptosis-inducing ligand induces neuronal death in a murine model of HIV central nervous system infection.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2777-82.
2003: Yasushi Miyahira; Masaharu Katae; Kazuyoshi Takeda; Hideo Yagita; Ko Okumura; Seiki Kobayashi; Tsutomu Takeuchi; Tsuneo Kamiyama; Yoshinosuke Fukuchi; Takashi Aoki
Activation of natural killer T cells by alpha-galactosylceramide impairs DNA vaccine-induced protective immunity against Trypanosoma cruzi.
Infection and immunity 2003;71(3):1234-41.
2003: Teruji Totsuka; Takanori Kanai; Ryoichi Iiyama; Koji Uraushihara; Motomi Yamazaki; Ryuichi Okamoto; Toshifumi Hibi; Katsunari Tezuka; Miyuki Azuma; Hisaya Akiba; Hideo Yagita; Ko Okumura; Mamoru Watanabe
Ameliorating effect of anti-inducible costimulator monoclonal antibody in a murine model of chronic colitis.
Gastroenterology 2003;124(2):410-21.
2003: Tatsuma Okazaki; Sachiko Sakon; Tomonari Sasazuki; Hiroaki Sakurai; Takahiro Doi; Hideo Yagita; Ko Okumura; Hiroyasu Nakano
Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses.
Biochemical and biophysical research communications 2003;300(4):807-12.
2003: Mark J Smyth; Kazuyoshi Takeda; Yoshihiro Hayakawa; Jacques J Peschon; Marcel R M van den Brink; Hideo Yagita
Nature's TRAIL--on a path to cancer immunotherapy.
Immunity 2003;18(1):1-6.
2003: Naoko Seki; Yoshihiro Hayakawa; Alan D Brooks; John Wine; Robert Wiltrout; Hideo Yagita; Jane E Tanner; Mark J Smyth; Thomas J Sayers
Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer.
Cancer research 2003;63(1):207-13.
2003: Masafumi Nakayama; Kazumi Ishidoh; Yuko Kojima; Norihiro Harada; Eiki Kominami; Ko Okumura; Hideo Yagita
Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(1):341-8.
2002: Norihiro Harada; Masafumi Nakayama; Hiroyasu Nakano; Yoshinosuke Fukuchi; Hideo Yagita; Ko Okumura
Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells.
Biochemical and biophysical research communications 2002;299(3):488-93.
2002: Monica Moro; Christophe Filippi; Alexandra Gallard; Laurent Malherbe; Gilles Foucras; Hisaya Akiba; Hideo Yagita; Jean-Charles Guéry; Nicolas Glaichenhaus
Blockade of CD86 in BALB/c mice infected with Leishmania major does not prevent the expansion of low avidity T cells.
European journal of immunology 2002;32(12):3566-75.
2002: Cornelius Schmaltz; Onder Alpdogan; Barry J Kappel; Stephanie J Muriglan; Jimmy A Rotolo; Jennifer Ongchin; Lucy M Willis; Andrew S Greenberg; Jeffrey M Eng; James M Crawford; George F Murphy; Hideo Yagita; Henning Walczak; Jacques J Peschon; Marcel R M van den Brink
T cells require TRAIL for optimal graft-versus-tumor activity.
Nature medicine 2002;8(12):1433-7.
2002: Yamazaki Tomohide; Hisaya Akiba; Hideyuki Iwai; Hironori Matsuda; Mami Aoki; Yuka Tanno; Tae Kwang Shin; Haruo Tsuchiya; Drew M Pardoll; Ko Okumura; Miyuki Azuma; Hideo Yagita
Expression of programmed death 1 ligands by murine T cells and APC.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5538-45.
2002: Josie Ursini-Siegel; Wenli Zhang; Anne Altmeyer; Eunice N Hatada; Richard K G Do; Hideo Yagita; Selina Chen-Kiang
TRAIL/Apo-2 ligand induces primary plasma cell apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5505-13.
2002: Mark J Smyth; Yoshihiro Hayakawa; Kazuyoshi Takeda; Hideo Yagita
New aspects of natural-killer-cell surveillance and therapy of cancer.
Nature reviews. Cancer 2002;2(11):850-61.
2002: Hideyuki Iwai; Yuko Kozono; Sachiko Hirose; Hisaya Akiba; Hideo Yagita; Ko Okumura; Hitoshi Kohsaka; Nobuyuki Miyasaka; Miyuki Azuma
Amelioration of collagen-induced arthritis by blockade of inducible costimulator-B7 homologous protein costimulation.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4332-9.
2002: Nobuhiko Kayagaki; Noriko Yamaguchi; Masaaki Abe; Sachiko Hirose; Toshikazu Shirai; Ko Okumura; Hideo Yagita
Suppression of antibody production by TNF-related apoptosis-inducing ligand (TRAIL).
Cellular immunology 2002;219(2):82-91.
2002: Delphine Bouchet; Laurent Tesson; Séverine Ménoret; Béatrice Charreau; Patrick Mathieu; Hideo Yagita; Ghislaine Duisit; Ignacio Anegon
Differential sensitivity of endothelial cells of various species to apoptosis induced by gene transfer of Fas ligand: role of FLIP levels.
Molecular medicine (Cambridge, Mass.) 2002;8(10):612-23.
2002: Michael Schmitt; Masanori Taniguchi; Toshimichi Yoshida; Yoshihiro Miyahara; Xiaogang Gu; Katanori Mukai; Hideo Yagita; Hartmut Dohner; Hiroshi Shiku
Rapid lethality of hosts by interleukin-12 following H-2 compatible allogeneic bone marrow transplantation: Reminiscence of gut-associated acute graft-versus-host reaction.
International journal of oncology 2002;21(4):795-801.
2002: Yoshiko Iwai; Taku Okazaki; Hiroyuki Nishimura; Akemi Kawasaki; Hideo Yagita; Tasuku Honjo
Microanatomical localization of PD-1 in human tonsils.
Immunology letters 2002;83(3):215-20.
2002: Yoshinobu Akiyama; Nozomu Shirasugi; Norio Uchida; Kenji Matsumoto; Masaki Kitajima; Hisashi Bashuda; Hideo Yagita; Ko Okumura; Osamu Aramaki; Masanori Niimi
B7/CTLA4 pathway is essential for generating regulatory cells after intratracheal delivery of alloantigen in mice.
Transplantation 2002;74(5):732-8.
2002: Masaharu Katae; Yasushi Miyahira; Kazuyoshi Takeda; Hironori Matsuda; Hideo Yagita; Ko Okumura; Tsutomu Takeuchi; Tsuneo Kamiyama; Akihiko Ohwada; Yoshinosuke Fukuchi; Takashi Aoki
Coadministration of an interleukin-12 gene and a Trypanosoma cruzi gene improves vaccine efficacy.
Infection and immunity 2002;70(9):4833-40.
2002: Yoshihiro Hayakawa; Kazuyoshi Takeda; Hideo Yagita; Mark J Smyth; Luc Van Kaer; Ko Okumura; Ikuo Saiki
IFN-gamma-mediated inhibition of tumor angiogenesis by natural killer T-cell ligand, alpha-galactosylceramide.
Blood 2002;100(5):1728-33.
2002: Yuko Kojima; Akemi Kawasaki-Koyanagi; Noriyoshi Sueyoshi; Atsushi Kanai; Hideo Yagita; Ko Okumura
Localization of Fas ligand in cytoplasmic granules of CD8+ cytotoxic T lymphocytes and natural killer cells: participation of Fas ligand in granule exocytosis model of cytotoxicity.
Biochemical and biophysical research communications 2002;296(2):328-36.
2002: Tomonari Sasazuki; Taisuke Sawada; Sachiko Sakon; Toshio Kitamura; Takuma Kishi; Tatsuma Okazaki; Mitsuo Katano; Masao Tanaka; Mamoru Watanabe; Hideo Yagita; Ko Okumura; Hiroyasu Nakano
Identification of a novel transcriptional activator, BSAC, by a functional cloning to inhibit tumor necrosis factor-induced cell death.
The Journal of biological chemistry 2002;277(32):28853-60.
2002: Lina Tian; Weihong Guo; Zhengwei Yuan; Vincent C H Lui; Jacqueline K Y Chan; Hideo Yagita; Hisaya Akiba; Margaret Dallman; Paul K H Tam
Association of the CD134/CD134L costimulatory pathway with acute rejection of small bowel allograft.
Transplantation 2002;74(1):133-8.
2002: Ja-Young Kim; Yun-Hee Kim; Inik Chang; Sunshin Kim; Youngmi Kim Pak; Byung-Ha Oh; Hideo Yagita; Yong-Keun Jung; Young Joon Oh; Myung-Shik Lee
Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis.
Oncogene 2002;21(20):3139-48.
2002: Yoshinori Seko; Shigeru Ishiyama; Toshiro Nishikawa; Takeshi Kasajima; Michiaki Hiroe; Shin Suzuki; Sugao Ishiwata; Sachio Kawai; Yuetsu Tanaka; Miyuki Azuma; Tetsuji Kobata; Hideo Yagita; Ko Okumura; Ryozo Nagai
Expression of tumor necrosis factor ligand superfamily costimulatory molecules CD27L, CD30L, OX40L and 4-1BBL in the heart of patients with acute myocarditis and dilated cardiomyopathy.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2002;11(3):166-70.
2002: Maki Nakayama; Masao Nagata; Hisafumi Yasuda; Kenji Arisawa; Reiko Kotani; Katsumi Yamada; Shahead Ali Chowdhury; Sagarika Chakrabarty; Zhen Zi Jin; Hideo Yagita; Koichi Yokono; Masato Kasuga
Fas/Fas ligand interactions play an essential role in the initiation of murine autoimmune diabetes.
Diabetes 2002;51(5):1391-7.
2002: Janice M Kelly; Kazuyoshi Takeda; Phillip K Darcy; Hideo Yagita; Mark J Smyth
A role for IFN-gamma in primary and secondary immunity generated by NK cell-sensitive tumor-expressing CD80 in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4472-9.
2002: Yoshinori Seko; Nobuhiko Kayagaki; Ken-ichiro Seino; Hideo Yagita; Ko Okumura; Ryozo Nagai
Role of Fas/FasL pathway in the activation of infiltrating cells in murine acute myocarditis caused by Coxsackievirus B3.
Journal of the American College of Cardiology 2002;39(8):1399-403.
2002: Elina Zuñiga; Claudia C Motran; Carolina L Montes; Hideo Yagita; Adriana Gruppi
Trypanosoma cruzi infection selectively renders parasite-specific IgG+ B lymphocytes susceptible to Fas/Fas ligand-mediated fratricide.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):3965-73.
2002: Mark J Smyth; Nadine Y Crowe; Yoshihiro Hayakawa; Kazuyoshi Takeda; Hideo Yagita; Dale I Godfrey
NKT cells - conductors of tumor immunity?
Current opinion in immunology 2002;14(2):165-71.
2002: Junichi Sugita; Haruo Ohtani; Takayuki Mizoi; Kazuya Saito; Ken-ichi Shiiba; Iwao Sasaki; Seiki Matsuno; Hideo Yagita; Masaaki Miyazawa; Hiroshi Nagura
Close association between Fas ligand (FasL; CD95L)-positive tumor-associated macrophages and apoptotic cancer cells along invasive margin of colorectal carcinoma: a proposal on tumor-host interactions.
Japanese journal of cancer research : Gann 2002;93(3):320-8.
2002: Masato Yamada; Hideo Yagita; Hideko Inoue; Tsuyoshi Takanashi; Hironori Matsuda; Eiko Munechika; Yutaka Kanamaru; Isao Shirato; Yasuhiko Tomino; Kouji Matushima; Ko Okumura; Hiroshi Hashimoto
Selective accumulation of CCR4+ T lymphocytes into renal tissue of patients with lupus nephritis.
Arthritis and rheumatism 2002;46(3):735-40.
2002: Toshiro Futagawa; Hisaya Akiba; Tomohiro Kodama; Kazuyoshi Takeda; Yasuyuki Hosoda; Hideo Yagita; Ko Okumura
Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells.
International immunology 2002;14(3):275-86.
2002: Tomohiro Watanabe; Masaru Yoshida; Yasuhiko Shirai; Masashi Yamori; Hideo Yagita; Toshiyuki Itoh; Tsutomu Chiba; Toru Kita; Yoshio Wakatsuki
Administration of an antigen at a high dose generates regulatory CD4+ T cells expressing CD95 ligand and secreting IL-4 in the liver.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(5):2188-99.
2002: Mark J Smyth; Nadine Y Crowe; Daniel G Pellicci; Konstantinos Kyparissoudis; Janice M Kelly; Kazuyoshi Takeda; Hideo Yagita; Dale I Godfrey
Sequential production of interferon-gamma by NK1.1(+) T cells and natural killer cells is essential for the antimetastatic effect of alpha-galactosylceramide.
Blood 2002;99(4):1259-66.
2002: Sunshin Kim; Ja Young Ki; Tae H Lee; Kyungho Suk; Hoon-Suk Cha; Eun-Mi Koh; Hideo Yagita; Myung-Shik Lee
Soluble Fas ligand-susceptible "memory" cells in mice but not in human: potential role of soluble Fas ligand in deletion of auto-reactive cells.
Autoimmunity 2002;35(1):15-20.
2002: Erika Cretney; Kazuyoshi Takeda; Hideo Yagita; Moira Glaccum; Jacques J Peschon; Mark J Smyth
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1356-61.
2002: Kazuyoshi Takeda; Mark J Smyth; Erika Cretney; Yoshihiro Hayakawa; Nobuhiko Kayagaki; Hideo Yagita; Ko Okumura
Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development.
The Journal of experimental medicine 2002;195(2):161-9.
2002: Masafumi Nakayama; Kazumi Ishidoh; Nobuhiko Kayagaki; Yuko Kojima; Noriko Yamaguchi; Hiroyasu Nakano; Eiki Kominami; Ko Okumura; Hideo Yagita
Multiple pathways of TWEAK-induced cell death.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):734-43.
2002: Fumie Kagaya; Junko Hori; Kazutaka Kamiya; Yuichi Kaji; Tetsuro Oshika; Shiro Amano; Satoru Yamagami; Tadahiko Tsuru; Sumiyoshi Tanaka; Hironori Matsuda; Hideo Yagita; Ko Okumura
Inhibition of murine corneal allograft rejection by treatment with antibodies to CD80 and CD86.
Experimental eye research 2002;74(1):131-9.
2002: Janice M Kelly; Phillip K Darcy; Jessica L Markby; Dale I Godfrey; Kazuyoshi Takeda; Hideo Yagita; Mark J Smyth
Induction of tumor-specific T cell memory by NK cell-mediated tumor rejection.
Nature immunology 2002;3(1):83-90.
2001: Kazuyoshi Takeda; Mark J Smyth; Erika Cretney; Yoshihiro Hayakawa; Noriko Yamaguchi; Hideo Yagita; Ko Okumura
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth.
Cellular immunology 2001;214(2):194-200.
2001: Yoshinori Seko; N Takahashi; H Oshima; O Shimozato; Hisaya Akiba; K Takeda; Tetsuji Kobata; Hideo Yagita; Ko Okumura; Masahiko Azuma; Ryozo Nagai
Expression of tumour necrosis factor (TNF) ligand superfamily co-stimulatory molecules CD30L, CD27L, OX40L, and 4-1BBL in murine hearts with acute myocarditis caused by Coxsackievirus B3.
The Journal of pathology 2001;195(5):593-603.
2001: K Sato; S Hida; Hiroshi Takayanagi; Taeko Yokochi; Nobuhiko Kayagaki; K Takeda; Hideo Yagita; Ko Okumura; Naomi Tanaka; Tadatsugu Taniguchi; Kouetsu Ogasawara
Antiviral response by natural killer cells through TRAIL gene induction by IFN-alpha/beta.
European journal of immunology 2001;31(11):3138-46.
2001: K Tada; Tatsuma Okazaki; Sachiko Sakon; T Kobarai; K Kurosawa; S Yamaoka; H Hashimoto; T W Mak; Hideo Yagita; Ko Okumura; Wen-Chen Yeh; Hiroyasu Nakano
Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death.
The Journal of biological chemistry 2001;276(39):36530-4.
2001: Aaruni Khanolkar; Hideo Yagita; Martin J Cannon
Preferential utilization of the perforin/granzyme pathway for lysis of Epstein-Barr virus-transformed lymphoblastoid cells by virus-specific CD4+ T cells.
Virology 2001;287(1):79-88.
2001: T Okazaki; Atsuhito Nakao; Hiroyasu Nakano; F Takahashi; Kyoko Takahashi; O Shimozato; Kazuyoshi Takeda; Hideo Yagita; Ko Okumura
Impairment of bleomycin-induced lung fibrosis in CD28-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):1977-81.
2001: Valeria M Borges; Haroldo Falcão; José Henrique Leite-Júnior; L Alvim; G P Teixeira; M Russo; Alberto Nóbrega; Marcela F Lopes; P M Rocco; Wendy F Davidson; Rafael Linden; Hideo Yagita; Walter A Zin; George A DosReis
Fas ligand triggers pulmonary silicosis.
The Journal of experimental medicine 2001;194(2):155-64.
2001: Yoshihiro Hayakawa; Kazuyoshi Takeda; Hideo Yagita; S Kakuta; Y Iwakura; Luc Van Kaer; Ikuo Saiki; Ko Okumura
Critical contribution of IFN-gamma and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of alpha-galactosylceramide.
European journal of immunology 2001;31(6):1720-7.
2001: Yoshihiro Hayakawa; Kazuyoshi Takeda; Hideo Yagita; Luc Van Kaer; Ikuo Saiki; Ko Okumura
Differential regulation of Th1 and Th2 functions of NKT cells by CD28 and CD40 costimulatory pathways.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):6012-8.
2001: Hiroko Fujimoto; Y Tanaka; Zhao-Jun Liu; Hideo Yagita; K Okumura; Atsushi Kosugi; Akio Morinobu; H Umehara; Hirohei Yamamura; Yasuhiro Minami
Down-regulation of alpha6 integrin, an anti-oncogene product, by functional cooperation of H-Ras and c-Myc.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(4):337-43.
2001: Y Miura; Naoko Misawa; N Maeda; Y Inagaki; Y Tanaka; M Ito; N Kayagaki; Naoki Yamamoto; Hideo Yagita; Hidehiro Mizusawa; Yoshio Koyanagi
Critical contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to apoptosis of human CD4+ T cells in HIV-1-infected hu-PBL-NOD-SCID mice.
The Journal of experimental medicine 2001;193(5):651-60.
2001: Tanuja Chitnis; Nader Najafian; Kald A Abdallah; Victor M Dong; Hideo Yagita; Mohamed H Sayegh; Samia J Khoury
CD28-independent induction of experimental autoimmune encephalomyelitis.
The Journal of clinical investigation 2001;107(5):575-83.
2001: Nozomu Shirasugi; Yoshifumi Ikeda; Yoshinobu Akiyama; Kenji Matsumoto; K Hamano; K Esato; Hisashi Bashuda; Hideo Yagita; Ko Okumura; Hiroshi Takami; Susumu Kodaira; Masanori Niimi
Induction of hyporesponsiveness to fully allogeneic cardiac grafts by intratracheal delivery of alloantigen.
Transplantation 2001;71(4):561-4.
2001: C Nohara; Hisaya Akiba; Atsuo Nakajima; A Inoue; C S Koh; H Ohshima; Hideo Yagita; Yoshikuni Mizuno; Ko Okumura
Amelioration of experimental autoimmune encephalomyelitis with anti-OX40 ligand monoclonal antibody: a critical role for OX40 ligand in migration, but not development, of pathogenic T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):2108-15.
2001: Kazuyoshi Takeda; Yoshihiro Hayakawa; Mark J Smyth; Nobuhiko Kayagaki; Noriko Yamaguchi; S Kakuta; Y Iwakura; Hideo Yagita; Ko Okumura
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells.
Nature medicine 2001;7(1):94-100.
2000: K Fujihira; Masao Nagata; Hiroaki Moriyama; Hisafumi Yasuda; Kenji Arisawa; Maki Nakayama; S Maeda; Masato Kasuga; K Okumura; Hideo Yagita; Koichi Yokono
Suppression and acceleration of autoimmune diabetes by neutralization of endogenous interleukin-12 in NOD mice.
Diabetes 2000;49(12):1998-2006.
2000: Masafumi Nakayama; Nobuhiko Kayagaki; Noriko Yamaguchi; Ko Okumura; Hideo Yagita
Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicity.
The Journal of experimental medicine 2000;192(9):1373-80.
2000: Nozomu Shirasugi; S Matsumoto; K Hamano; K Esato; Kenji Matsumoto; Hisashi Bashuda; Hideo Yagita; Ko Okumura; Yoshifumi Ikeda; Hiroshi Takami; Susumu Kodaira; Masanori Niimi
Survival of fully allogeneic cardiac allografts induced by delivery of alloantigen via respiratory mucosa is abrogated by blockade of the B7 pathway.
Transplantation proceedings 2000;32(7):2034.
2000: Benjamin Trinité; Cécile Voisine; Hideo Yagita; Régis Josien
A subset of cytolytic dendritic cells in rat.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(8):4202-8.
2000: T Yoshioka; A Nakajima; H Akiba; Toshiyuki Ishiwata; Goro Asano; Shinichi Yoshino; Hideo Yagita; K Okumura
Contribution of OX40/OX40 ligand interaction to the pathogenesis of rheumatoid arthritis.
European journal of immunology 2000;30(10):2815-23.
2000: Fumiko Nagao; M Suzui; K Takeda; Hideo Yagita; Ko Okumura
Mobilization of NK cells by exercise: downmodulation of adhesion molecules on NK cells by catecholamines.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(4):R1251-6.
2000: A Nakajima; H Oshima; C Nohara; S Morimoto; Shinichi Yoshino; Tetsuji Kobata; Hideo Yagita; K Okumura
Involvement of CD70-CD27 interactions in the induction of experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 2000;109(2):188-96.
2000: Yoshinori Seko; N Takahashi; Yusuke Tada; Hideo Yagita; Ko Okumura; Ryozo Nagai
Restricted usage of T-cell receptor Vgamma-Vdelta genes and expression of costimulatory molecules in Takayasu's arteritis.
International journal of cardiology 2000;75 Suppl 1():S77-83; discussion S85-7.
2000: K Hattori; Takao Hirano; Kazuo Oshimi; Hideo Yagita; Ko Okumura
A metalloproteinase inhibitor prevents acute graft-versus-host disease while preserving the graft-versus-leukaemia effect of allogeneic bone marrow transplantation.
Leukemia & lymphoma 2000;38(5-6):553-61.
2000: A Saitoh; T Kawanabe; H Weidong; N Kayagaki; T Kawamura; Hideo Yagita; K Okumura; Shinji Shimada
Selective upregulation of fibroblast Fas ligand expression, and prolongation of Fas/Fas ligand-mediated skin allograft survival, by retinoic acid: the skin as a retinoide-inducible immune privilege site.
The Journal of investigative dermatology 2000;115(2):154-61.
2000: Thomas J Sayers; Alan D Brooks; Naoko Seki; Mark J Smyth; Hideo Yagita; Bruce R Blazar; Anatoli Malyguine
T cell lysis of murine renal cancer: multiple signaling pathways for cell death via Fas.
Journal of leukocyte biology 2000;68(1):81-6.
2000: Kazuyoshi Takeda; Y Hayakawa; M Atsuta; S Hong; L Van Kaer; K Kobayashi; M Ito; Hideo Yagita; Ko Okumura
Relative contribution of NK and NKT cells to the anti-metastatic activities of IL-12.
International immunology 2000;12(6):909-14.
2000: Z Luo; M Gotoh; TR Grochowiecki; Toshiyuki Tanaka; F Kimura; Hiroto Kawashima; Hideo Yagita; K Okumura; Masayuki Miyasaka
Anergic T cells generated in vitro suppress rejection response to islet allografts.
Transplantation 2000;69(10):2144-8.
2000: Kazuyoshi Takeda; Y Hayakawa; L Van Kaer; H Matsuda; Hideo Yagita; Ko Okumura
Critical contribution of liver natural killer T cells to a murine model of hepatitis.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5498-503.
2000: TR Grochowiecki; M Gotoh; Keizo Dono; Yutaka Takeda; Masato Sakon; Hideo Yagita; K Okumura; Masayuki Miyasaka; Morito Monden
Induction of unresponsiveness to islet xenograft by MMC treatment of graft and blockage of LFA-1/ICAM-1 pathway.
Transplantation 2000;69(8):1567-71.
2000: Y Satake; Hisaya Akiba; Kazuyoshi Takeda; M Atsuta; Hideo Yagita; Ko Okumura
Characterization of rat OX40 ligand by monoclonal antibody.
Biochemical and biophysical research communications 2000;270(3):1041-8.
2000: M Iwao; So-ichiro Fukada; T Harada; Kazutake Tsujikawa; Hideo Yagita; C Hiramine; Y Miyagoe; Shin'ichi Takeda; Hirofumi Yamamoto
Interaction of merosin (laminin 2) with very late activation antigen-6 is necessary for the survival of CD4+ CD8+ immature thymocytes.
Immunology 2000;99(4):481-8.
2000: N Tsukada; Hisaya Akiba; Tetsuji Kobata; Y Aizawa; Hideo Yagita; Ko Okumura
Blockade of CD134 (OX40)-CD134L interaction ameliorates lethal acute graft-versus-host disease in a murine model of allogeneic bone marrow transplantation.
Blood 2000;95(7):2434-9.
2000: H Shinohara; Hideo Yagita; Y Ikawa; Naoki Oyaizu
Fas drives cell cycle progression in glioma cells via extracellular signal-regulated kinase activation.
Cancer research 2000;60(6):1766-72.
2000: Sunshin Kim; K A Kim; D Y Hwang; T H Lee; N Kayagaki; Hideo Yagita; Myung-Shik Lee
Inhibition of autoimmune diabetes by Fas ligand: the paradox is solved.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(6):2931-6.
2000: A Nakajima; H Hirai; N Kayagaki; S Yoshino; S Hirose; Hideo Yagita; K Okumura
Treatment of lupus in NZB/W F1 mice with monoclonal antibody against Fas ligand.
Journal of autoimmunity 2000;14(2):151-7.
2000: Kazuyoshi Takeda; H Oshima; Y Hayakawa; Hisaya Akiba; M Atsuta; Tetsuji Kobata; K Kobayashi; M Ito; Hideo Yagita; Ko Okumura
CD27-mediated activation of murine NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(4):1741-5.
2000: T Kawamura; Miyuki Azuma; N Kayagaki; S Shimada; Hideo Yagita; Ko Okumura
Fas/Fas ligand-mediated apoptosis of murine Langerhans cells.
Journal of dermatological science 2000;22(2):96-101.
2000: Hisaya Akiba; Yasushi Miyahira; M Atsuta; Kazuyoshi Takeda; C Nohara; Toshiro Futagawa; Hironori Matsuda; Takashi Aoki; Hideo Yagita; Ko Okumura
Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis.
The Journal of experimental medicine 2000;191(2):375-80.
1999: Y Shirakata; K Ishii; Hideo Yagita; K Okumura; M Taniguchi; Toshitada Takemori
Distinct subcellular localization and substrate specificity of extracellular signal-regulated kinase in B cells upon stimulation with IgM and CD40.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6589-97.
1999: A Inoue; C S Koh; M Yamazaki; Hideo Yagita
Effect of anti-B7-1 and anti-B7-2 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(11):6180-6.
1999: Zhao-Jun Liu; Y Tanaka; Hiroko Fujimoto; S Mine; Akio Morinobu; Hideo Yagita; K Okumura; Isao Oishi; J Udagawa; Hirohei Yamamura; Yasuhiro Minami
A novel role for H-Ras in the regulation of very late antigen-4 integrin and VCAM-1 via c-Myc-dependent and -independent mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(9):4901-8.
1999: H Morita; Kazuyoshi Takeda; Hideo Yagita; Ko Okumura
Immunosuppressive effect of leukotriene B(4) receptor antagonist in vitro.
Biochemical and biophysical research communications 1999;264(2):321-6.
1999: Hiroyasu Nakano; Sachiko Sakon; H Koseki; T Takemori; K Tada; M Matsumoto; E Munechika; T Sakai; T Shirasawa; Hisaya Akiba; Tetsuji Kobata; SM Santee; Carl Ware; P D Rennert; M Taniguchi; Hideo Yagita; Ko Okumura
Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9803-8.
1999: Nobuhiko Kayagaki; Noriko Yamaguchi; Masafumi Nakayama; Kazuyoshi Takeda; Hisaya Akiba; H Tsutsui; H Okamura; K Nakanishi; Ko Okumura; Hideo Yagita
Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(4):1906-13.
1999: T Kawamura; Miyuki Azuma; N Kayagaki; S Shimada; Hideo Yagita; Ko Okumura
Fas/Fas ligand-mediated elimination of antigen-bearing Langerhans cells in draining lymph nodes.
The British journal of dermatology 1999;141(2):201-5.
1999: Yoshinori Seko; N Takahashi; H Oshima; O Shimozato; Hisaya Akiba; Tetsuji Kobata; Hideo Yagita; Ko Okumura; Masahiko Azuma; Yoshio Yazaki
Expression of tumour necrosis factor (TNF) receptor/ligand superfamily co-stimulatory molecules CD40, CD30L, CD27L, and OX40L in murine hearts with chronic ongoing myocarditis caused by coxsackie virus B3.
The Journal of pathology 1999;188(4):423-30.
1999: Hisaya Akiba; H Oshima; Kazuyoshi Takeda; M Atsuta; Hiroyasu Nakano; Atsuo Nakajima; C Nohara; Hideo Yagita; Ko Okumura
CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7058-66.
1999: K Hattori; Takao Hirano; C Ushiyama; Hiroaki Miyajima; N Yamakawa; S Ikeda; K Yoshino; Masatoshi Tateno; Kazuo Oshimi; Nobuhiko Kayagaki; Hideo Yagita; Ko Okumura
A metalloproteinase inhibitor prevents acute graft-versus-host disease in mice after bone marrow transplantation.
Bone marrow transplantation 1999;23(12):1283-9.
1999: Nobuhiko Kayagaki; Noriko Yamaguchi; Masafumi Nakayama; H Eto; Ko Okumura; Hideo Yagita
Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs.
The Journal of experimental medicine 1999;189(9):1451-60.
1999: Yoshinori Seko; N Takahashi; Hideo Yagita; Ko Okumura; Masahiko Azuma; Yoshio Yazaki
Effects of in vivo administration of anti-B7-1/B7-2 monoclonal antibodies on the survival of mice with chronic ongoing myocarditis caused by Coxsackievirus B3.
The Journal of pathology 1999;188(1):107-12.
1999: N Tsukada; Tetsuji Kobata; Y Aizawa; Hideo Yagita; Ko Okumura
Graft-versus-leukemia effect and graft-versus-host disease can be differentiated by cytotoxic mechanisms in a murine model of allogeneic bone marrow transplantation.
Blood 1999;93(8):2738-47.
1999: N Suzuki; A Nakajima; Shinichi Yoshino; K Matsushima; Hideo Yagita; K Okumura
Selective accumulation of CCR5+ T lymphocytes into inflamed joints of rheumatoid arthritis.
International immunology 1999;11(4):553-9.
1999: K Hattori; Takao Hirano; Hiroaki Miyajima; N Yamakawa; S Ikeda; K Yoshino; Masatoshi Tateno; Kazuo Oshimi; Nobuhiko Kayagaki; Hideo Yagita; Ko Okumura
A metalloproteinase inhibitor prevents acute graft-versus-host disease while preserving the graft-versus-leukaemia effect of allogeneic bone marrow transplantation.
British journal of haematology 1999;105(1):303-12.
1999: T Kodama; Kazuyoshi Takeda; O Shimozato; Yoshihiro Hayakawa; M Atsuta; K Kobayashi; M Ito; Hideo Yagita; Ko Okumura
Perforin-dependent NK cell cytotoxicity is sufficient for anti-metastatic effect of IL-12.
European journal of immunology 1999;29(4):1390-6.
1999: O Shimozato; Kazuyoshi Takeda; Hideo Yagita; Ko Okumura
Expression of CD30 ligand (CD153) on murine activated T cells.
Biochemical and biophysical research communications 1999;256(3):519-26.
1999: T Takada; K Kato; Hideo Yagita; H Hamada; Ko Okumura
Effects of immunization with tumor cells double transfected with interleukin-2 (IL-2) and interleukin-12 (IL-12) genes on artificial metastasis of colon26 cells in BALB/c mice.
Clinical & experimental metastasis 1999;17(2):125-30.
1999: Nobuhiko Kayagaki; Noriko Yamaguchi; Masafumi Nakayama; A Kawasaki; Hisaya Akiba; Ko Okumura; Hideo Yagita
Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(5):2639-47.
1999: TR Grochowiecki; M Gotoh; Keizo Dono; Yutaka Takeda; Hiroki Ohzato; M Okuyama; J Shimizu; F Kimura; L He; Hiroaki Nagano; S Nakamori; Koji Umeshita; Masato Sakon; Hideo Yagita; K Okumura; Morito Monden
Pretreatment of islets with mitomycin C and blockage of costimulatory signal induces unresponsiveness to islet xenografts.
Transplantation proceedings 1999;31(1-2):925.
1999: T Kawahara; Hideo Yagita; Ko Okumura; Shunji Futagawa
T cell-mediated effector mechanisms in the rejection of allogeneically transplanted hepatocytes.
Transplantation proceedings 1999;31(1-2):830-1.
1999: Z Luo; M Gotoh; TR Grochowiecki; Toshiyuki Tanaka; F Kimura; Hiroto Kawashima; Hideo Yagita; K Okumura; Masayuki Miyasaka
Anergic cells generated in vitro suppress rejection response to islet allografts.
Transplantation proceedings 1999;31(1-2):623.
1999: Y H Kim; S Kim; K A Kim; Hideo Yagita; N Kayagaki; K W Kim; M S Lee
Apoptosis of pancreatic beta-cells detected in accelerated diabetes of NOD mice: no role of Fas-Fas ligand interaction in autoimmune diabetes.
European journal of immunology 1999;29(2):455-65.
1999: N Takahashi; Yoshinori Seko; Masahiko Azuma; Hideo Yagita; Ko Okumura; Yoshio Yazaki
Evidence of cell-mediated cardiac myocyte injury involved in the heart failure of a patient with progressive systemic sclerosis.
Japanese circulation journal 1999;63(1):68-72.
1998: Zhao-Jun Liu; Y Tanaka; S Mine; Akio Morinobu; Hideo Yagita; K Okumura; T Taniguchi; Hirohei Yamamura; Yasuhiro Minami
Functional cooperation of cyclin C and c-Myc in mediating homotypic cell adhesion via very late antigen-4 activation and vascular cell adhesion molecule-1 induction.
Blood 1998;92(12):4700-11.
1998: K Seino; Kazuhisa Iwabuchi; Nobuhiko Kayagaki; R Miyata; Isao Nagaoka; A Matsuzawa; K Fukao; Hideo Yagita; Ko Okumura
Chemotactic activity of soluble Fas ligand against phagocytes.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4484-8.
1998: Hisaya Akiba; M Atsuta; Hideo Yagita; Ko Okumura
Identification of rat OX40 ligand by molecular cloning.
Biochemical and biophysical research communications 1998;251(1):131-6.
1998: S Hibino; K Kato; S Kudoh; Hideo Yagita; K Okumura
Tenascin suppresses CD3-mediated T cell activation.
Biochemical and biophysical research communications 1998;250(1):119-24.
1998: T Kawahara; Hideo Yagita; S Kasai; M Sawa; K Kato; Ko Okumura; Shunji Futagawa; M Mito
Allogeneic hepatocyte transplantation: contribution of Fas-Fas ligand interaction to allogeneic hepatocyte rejection.
Journal of gastroenterology and hepatology 1998;13 Suppl():S119-23.
1998: Yoshinori Seko; N Takahashi; Masahiko Azuma; Hideo Yagita; Ko Okumura; Yoshio Yazaki
Expression of costimulatory molecule CD40 in murine heart with acute myocarditis and reduction of inflammation by treatment with anti-CD40L/B7-1 monoclonal antibodies.
Circulation research 1998;83(4):463-9.
1998: Atsuo Nakajima; T Kodama; S Morimoto; Miyuki Azuma; Kazuyoshi Takeda; H Oshima; S Yoshino; Hideo Yagita; Ko Okumura
Antitumor effect of CD40 ligand: elicitation of local and systemic antitumor responses by IL-12 and B7.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1901-7.
1998: Cheung-Seog Park; Y Yashiro; Xu-Guang Tai; Kazuhito Toyo-Oka; Toshiyuki Hamaoka; Hideo Yagita; K Okumura; S Neben; Hiromi Fujiwara
Differential involvement of a Fas-CPP32-like protease pathway in apoptosis of TCR/CD9-costimulated, naive T cells and TCR-restimulated, activated T cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(12):5790-6.
1998: C Sekine; Hideo Yagita; N Miyasaka; Ko Okumura
Expression and function of CD40 in rheumatoid arthritis synovium.
The Journal of rheumatology 1998;25(6):1048-53.
1998: K Hattori; Takao Hirano; Hiroaki Miyajima; N Yamakawa; Masatoshi Tateno; Kazuo Oshimi; Nobuhiko Kayagaki; Hideo Yagita; Ko Okumura
Differential effects of anti-Fas ligand and anti-tumor necrosis factor alpha antibodies on acute graft-versus-host disease pathologies.
Blood 1998;91(11):4051-5.
1998: Hisaya Akiba; Hiroyasu Nakano; S Nishinaka; M Shindo; Tetsuji Kobata; M Atsuta; Chikao Morimoto; Carl Ware; NL Malinin; David Wallach; Hideo Yagita; Ko Okumura
CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase.
The Journal of biological chemistry 1998;273(21):13353-8.
1998: Y Ohtsuka; K Udaka; Y Yamashiro; Hideo Yagita; Ko Okumura
Dystrophin acts as a transplantation rejection antigen in dystrophin-deficient mice: implication for gene therapy.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4635-40.
1998: Y Ohta; M Gotoh; Hiroki Ohzato; T Fukuzaki; M Nishihara; Keizo Dono; Koji Umeshita; Masato Sakon; Hideo Yagita; K Okumura; Toshiyuki Tanaka; Hiroto Kawashima; Masayuki Miyasaka; Morito Monden
Direct antigen presentation through binding of donor intercellular adhesion molecule-1 to recipient lymphocyte function-associated antigen-1 molecules in xenograft rejection.
Transplantation 1998;65(8):1094-100.
1998: H Oshima; Hiroyasu Nakano; C Nohara; Tetsuji Kobata; A Nakajima; N A Jenkins; D J Gilbert; N G Copeland; T Muto; Hideo Yagita; Ko Okumura
Characterization of murine CD70 by molecular cloning and mAb.
International immunology 1998;10(4):517-26.
1998: Hiroyasu Nakano; M Shindo; Sachiko Sakon; S Nishinaka; M Mihara; Hideo Yagita; Ko Okumura
Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3537-42.
1998: Yoshinori Seko; N Takahashi; Masahiko Azuma; Hideo Yagita; Ko Okumura; Yoshio Yazaki
Effects of in vivo administration of anti-B7-1/B7-2 monoclonal antibodies on murine acute myocarditis caused by coxsackievirus B3.
Circulation research 1998;82(5):613-8.
1998: M Shindo; Hiroyasu Nakano; Hidehito Kuroyanagi; Takuji Shirasawa; M Mihara; D J Gilbert; N A Jenkins; N G Copeland; Hideo Yagita; Ko Okumura
cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2.
Biochemical and biophysical research communications 1998;244(1):285-92.
1998: Yutaka Takeda; M Gotoh; Keizo Dono; M Nishihara; TR Grochowiecki; F Kimura; T Yoshida; Y Ohta; H Ota; Hiroki Ohzato; Koji Umeshita; T Takeda; N Matsuura; Masato Sakon; N Kayagaki; Hideo Yagita; K Okumura; Masayuki Miyasaka; Morito Monden
Protection of islet allografts transplanted together with Fas ligand expressing testicular allografts.
Diabetologia 1998;41(3):315-21.
1998: Yoshinori Seko; N Takahashi; Shigeru Ishiyama; Toshiro Nishikawa; Takeshi Kasajima; Michiaki Hiroe; Shin Suzuki; Sugao Ishiwata; S Kawai; Masahiko Azuma; Hideo Yagita; Ko Okumura; Yoshio Yazaki
Expression of costimulatory molecules B7-1, B7-2, and CD40 in the heart of patients with acute myocarditis and dilated cardiomyopathy.
Circulation 1998;97(7):637-9.
1998: M Shindo; Hiroyasu Nakano; Sachiko Sakon; Hideo Yagita; M Mihara; Ko Okumura
Assignment of IkappaB kinase beta (IKBKB) to human chromosome band 8p12-->p11 by in situ hybridization.
Cytogenetics and cell genetics 1998;82(1-2):32-3.
1998: Toshihiko Kawamura; K Takeda; S K Mendiratta; Hiroki Kawamura; L Van Kaer; Hideo Yagita; Toru Abo; Ko Okumura
Critical role of NK1+ T cells in IL-12-induced immune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):16-9.
1997: Yasuko Tsunetsugu-Yokota; S Yasuda; A Sugimoto; T Yagi; M Azuma; Hideo Yagita; Kiyoko S Akagawa; Toshitada Takemori
Efficient virus transmission from dendritic cells to CD4+ T cells in response to antigen depends on close contact through adhesion molecules.
Virology 1997;239(2):259-68.
1997: Yoshinori Seko; Osamu Sato; A Takagi; Yusuke Tada; H Matsuo; Hideo Yagita; Ko Okumura; Yoshio Yazaki
Perforin-secreting killer cell infiltration in the aortic tissue of patients with atherosclerotic aortic aneurysm.
Japanese circulation journal 1997;61(12):965-70.
1997: M Nishihara; M Gotoh; Hiroki Ohzato; Y Ohta; Z Luo; Keizo Dono; Koji Umeshita; Masato Sakon; Morito Monden; Hideo Yagita; K Okumura; Masayuki Miyasaka
Awareness of donor alloantigens in antiadhesion therapy induces antigen-specific unresponsiveness to islet allografts.
Transplantation 1997;64(7):965-70.
1997: Kenichiro Seino; Nobuhiko Kayagaki; N Tsukada; K Fukao; Hideo Yagita; Ko Okumura
Transplantation of CD95 ligand-expressing grafts: influence of transplantation site and difficulty in protecting allo- and xenografts.
Transplantation 1997;64(7):1050-4.
1997: T Kawahara; Shinichi Kasai; Hideo Yagita; M Sawa; K Kato; M Azuma; A Nakajima; Ko Okumura; Shunji Futagawa; M Mito
Critical role of Fas/Fas ligand interaction in CD28-independent pathway of allogeneic murine hepatocyte rejection.
Hepatology (Baltimore, Md.) 1997;26(4):944-8.
1997: K Seino; N Kayagaki; Kazuyoshi Takeda; K Fukao; Ko Okumura; Hideo Yagita
Contribution of Fas ligand to T cell-mediated hepatic injury in mice.
Gastroenterology 1997;113(4):1315-22.
1997: Naoki Oyaizu; Nobuhiko Kayagaki; Hideo Yagita; Savita Pahwa; Yoji Ikawa
Requirement of cell-cell contact in the induction of Jurkat T cell apoptosis: the membrane-anchored but not soluble form of FasL can trigger anti-CD3-induced apoptosis in Jurkat T cells.
Biochemical and biophysical research communications 1997;238(2):670-5.
1997: Yoshinori Seko; N Takahashi; Hideo Yagita; Ko Okumura; Yoshio Yazaki
Expression of cytokine mRNAs in murine hearts with acute myocarditis caused by coxsackievirus b3.
The Journal of pathology 1997;183(1):105-8.
1997: Naoto Hirano; Tokiharu Takahashi; T Takahashi; Masahiko Azuma; Ko Okumura; Yoshio Yazaki; Hideo Yagita; Hisamura Hirai
Protective and therapeutic immunity against leukemia induced by irradiated B7-1 (CD80)-transduced leukemic cells.
Human gene therapy 1997;8(11):1375-84.
1997: K Hattori; Takao Hirano; C Ushiyama; Hiroaki Miyajima; N Yamakawa; T Ebata; Y Wada; S Ikeda; K Yoshino; Masatoshi Tateno; Kazuo Oshimi; Nobuhiko Kayagaki; Hideo Yagita; Ko Okumura
A metalloproteinase inhibitor prevents lethal acute graft-versus-host disease in mice.
Blood 1997;90(2):542-8.
1997: Keiko Maeda; T Sato; Miyuki Azuma; Hideo Yagita; Ko Okumura
Characterization of rat CD80 and CD86 by molecular cloning and mAb.
International immunology 1997;9(7):993-1000.
1997: A Enomoto; K Kato; Hideo Yagita; Ko Okumura
Adoptive transfer of cytotoxic T lymphocytes induced by CD86-transfected tumor cells suppresses multi-organ metastases of C1300 neuroblastoma in mice.
Cancer immunology, immunotherapy : CII 1997;44(4):204-10.
1997: T Kawahara; Shinichi Kasai; Hideo Yagita; K Kato; M Sawa; A Nakajima; M Azuma; Ko Okumura; Shunji Futagawa; M Mito
Involvement of Fas and Fas ligand interaction in allogeneic hepatocyte rejection in the spleen.
Transplantation proceedings 1997;29(4):2187-8.
1997: Kazuhisa Nozawa; N Kayagaki; Yoshiaki Tokano; Hideo Yagita; Ko Okumura; H Hasimoto
Soluble Fas (APO-1, CD95) and soluble Fas ligand in rheumatic diseases.
Arthritis and rheumatism 1997;40(6):1126-9.
1997: Hiroyasu Nakano; M Shindo; K Yamada; M C Yoshida; SM Santee; Carl Ware; N A Jenkins; D J Gilbert; Hideo Yagita; N C Copeland; Ko Okumura
Human TNF receptor-associated factor 5 (TRAF5): cDNA cloning, expression and assignment of the TRAF5 gene to chromosome 1q32.
Genomics 1997;42(1):26-32.
1997: Atsuo Nakajima; N Watanabe; S Yoshino; Hideo Yagita; Ko Okumura; Miyuki Azuma
Requirement of CD28-CD86 co-stimulation in the interaction between antigen-primed T helper type 2 and B cells.
International immunology 1997;9(5):637-44.
1997: N Kayagaki; N Yamaguchi; Fumiko Nagao; S Matsuo; H Maeda; Ko Okumura; Hideo Yagita
Polymorphism of murine Fas ligand that affects the biological activity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3914-9.
1997: Naoto Hirano; Tokiharu Takahashi; T Takahashi; Masahiko Azuma; Yoshio Yazaki; Hideo Yagita; Hisamura Hirai
Protective and therapeutic immunity against leukemia induced by irradiated B7-1 (CD80)-transduced leukemic cells.
Leukemia 1997;11 Suppl 3():577-81.
1997: K Kato; Ko Okumura; Hideo Yagita
Immunoregulation by B7 and IL-12 gene transfer.
Leukemia 1997;11 Suppl 3():572-6.
1997: H Sagara; Hironori Matsuda; N Wada; Hideo Yagita; T Fukuda; Ko Okumura; S Makino; Chisei Ra
A monoclonal antibody against very late activation antigen-4 inhibits eosinophil accumulation and late asthmatic response in a guinea pig model of asthma.
International archives of allergy and immunology 1997;112(3):287-94.
1997: Y Ohta; M Gotoh; Hiroki Ohzato; M Nishihara; Keizo Dono; Koji Umeshita; Masato Sakon; Morito Monden; Hideo Yagita; K Okumura; Hiroto Kawashima; Masayuki Miyasaka
Both donor and recipient adhesion molecules play a crucial role in inducing rejection of rat xenogeneic islets in mice.
Transplantation proceedings 1997;29(1-2):953.
1997: Kenichiro Seino; Nobuhiko Kayagaki; K Fukao; Ko Okumura; Hideo Yagita
Rejection of Fas ligand-expressing grafts.
Transplantation proceedings 1997;29(1-2):1092-3.
1997: K Seino; Nobuhiko Kayagaki; Ko Okumura; Hideo Yagita
Antitumor effect of locally produced CD95 ligand.
Nature medicine 1997;3(2):165-70.
1997: Atsuo Nakajima; Sachiko Hirose; Hideo Yagita; Ko Okumura
Roles of IL-4 and IL-12 in the development of lupus in NZB/W F1 mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(3):1466-72.
1997: Shin Aizawa; Hiroyasu Nakano; Takaomi Ishida; Ryouichi Horie; M Nagai; Kousei Ito; Hideo Yagita; Ko Okumura; Jun-Ichiro Inoue; Tomomi Watanabe
Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation.
The Journal of biological chemistry 1997;272(4):2042-5.
1997: Hisashi Bashuda; Kenichiro Seino; C Ra; Hideo Yagita; Ko Okumura
Lack of cognate help by CD4+ T cells and anergy of CD8+ T cells are the principal mechanisms for anti-leukocyte function-associated antigen-1/intercellular adhesion molecule-1-induced cardiac allograft tolerance.
Transplantation 1997;63(1):113-8.
1997: Hideki Nakano; T Tamura; Takayuki Yoshimoto; Hideo Yagita; Masayuki Miyasaka; E C Butcher; H Nariuchi; Terutaka Kakiuchi; Akio Matsuzawa
Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes.
European journal of immunology 1997;27(1):215-21.
1997: H Takenaka; S Maruo; N Yamamoto; M Wysocka; Shiro Ono; Masatoshi Kobayashi; Hideo Yagita; K Okumura; Toshiyuki Hamaoka; G Trinchieri; Hiromi Fujiwara
Regulation of T cell-dependent and -independent IL-12 production by the three Th2-type cytokines IL-10, IL-6, and IL-4.
Journal of leukocyte biology 1997;61(1):80-7.
1997: S Maruo; Masatsugu Oh-hora; Hyun-Jong Ahn; Shiro Ono; M Wysocka; Y Kaneko; Hideo Yagita; K Okumura; Hitoshi Kikutani; Tadamitsu Kishimoto; Masatoshi Kobayashi; Toshiyuki Hamaoka; G Trinchieri; Hiromi Fujiwara
B cells regulate CD40 ligand-induced IL-12 production in antigen-presenting cells (APC) during T cell/APC interactions.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(1):120-6.
1996: Yoshinori Seko; Hideo Yagita; K Okumura; Y Yazaki
Expression of vascular cell adhesion molecule-1 in murine hearts with acute myocarditis caused by coxsackievirus B3.
The Journal of pathology 1996;180(4):450-4.
1996: K Saito; Hideo Yagita; Hiroshi Hashimoto; K Okumura; Miyuki Azuma
Effect of CD80 and CD86 blockade and anti-interleukin-12 treatment on mouse acute graft-versus-host disease.
European journal of immunology 1996;26(12):3098-106.
1996: Y Kaneko; Sachiko Hirose; Masaaki Abe; Hideo Yagita; K Okumura; T Shirai
CD40-mediated stimulation of B1 and B2 cells: implication in autoantibody production in murine lupus.
European journal of immunology 1996;26(12):3061-5.
1996: Yoshinori Seko; Y Enokawa; T Tamatani; R Kannagi; Hideo Yagita; K Okumura; Y Yazaki
Expression of sialyl Lewis(X) in rat heart with ischaemia/reperfusion and reduction of myocardial reperfusion injury by a monoclonal antibody against sialyl Lewis(X)
The Journal of pathology 1996;180(3):305-10.
1996: Yoshinori Seko; Y Enokawa; T Tamatani; R Kannagi; Hideo Yagita; K Okumura; Y Yazaki
Induction of sialyl Lewis(X) on the surface of cultured rat vascular endothelial cells and cardiac myocytes by hypoxia/reoxygenation in vitro.
The Journal of pathology 1996;180(3):300-4.
1996: Hiroshi Kaneko; K Saito; Hiroshi Hashimoto; Hideo Yagita; K Okumura; Miyuki Azuma
Preferential elimination of CD28+ T cells in systemic lupus erythematosus (SLE) and the relation with activation-induced apoptosis.
Clinical and experimental immunology 1996;106(2):218-29.
1996: C Sekine; Hideo Yagita; T Kobata; Tomoko Hasunuma; K Nishioka; K Okumura
Fas-mediated stimulation induces IL-8 secretion by rheumatoid arthritis synoviocytes independently of CPP32-mediated apoptosis.
Biochemical and biophysical research communications 1996;228(1):14-20.
1996: H Moriyama; Koichi Yokono; K Amano; Masao Nagata; Y Hasegawa; N Okamoto; K Tsukamoto; M Miki; R Yoneda; N Yagi; Y Tominaga; H Kikutani; K Hioki; K Okumura; Hideo Yagita; M Kasuga
Induction of tolerance in murine autoimmune diabetes by transient blockade of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 pathway.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(8):3737-43.
1996: Atsuyuki Yamataka; Yoshifumi Kato; T Fujiwara; Hideo Yagita; K Okumura; M Sunagawa; M Nozawa; Takeshi Miyano
Impact of antibodies to leukocyte function-associated antigen-1 and intercellular adhesion molecule-1 on fetal bowel allo- and xenotransplantation in mice.
Transplantation proceedings 1996;28(5):2494-5.
1996: Yoshinori Seko; Masahiko Azuma; Hideo Yagita; K Okumura; Y Yazaki
Perforin-positive leukemic cell infiltration in the aortic tissue of a patient with T-cell prolymphocytic leukemia.
International angiology : a journal of the International Union of Angiology 1996;15(3):245-8.
1996: K Seino; Nobuhiko Kayagaki; H Bashuda; K Okumura; Hideo Yagita
Contribution of Fas ligand to cardiac allograft rejection.
International immunology 1996;8(9):1347-54.
1996: Yoshiaki Tokano; S Miyake; Nobuhiko Kayagaki; Kazuhisa Nozawa; S Morimoto; Miyuki Azuma; Hideo Yagita; Yoshinari Takasaki; K Okumura; Hiroshi Hashimoto
Soluble Fas molecule in the serum of patients with systemic lupus erythematosus.
Journal of clinical immunology 1996;16(5):261-5.
1996: K Kato; O Shimozato; K Hoshi; H Wakimoto; H Hamada; Hideo Yagita; K Okumura
Local production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9085-9.
1996: H Bashuda; K Takazawa; T Tamatani; M Miyasaka; Hideo Yagita; K Okumura
Induction of persistent allograft tolerance in the rat by combined treatment with anti-leukocyte function-associated antigen-1 and anti-intercellular adhesion molecule-1 monoclonal antibodies, donor-specific transfusion, and FK506.
Transplantation 1996;62(1):117-22.
1996: M Kashiwada; Y Kaneko; Hideo Yagita; K Okumura; Toshitada Takemori
Activation of mitogen-activated protein kinases via CD40 is distinct from that stimulated by surface IgM on B cells.
European journal of immunology 1996;26(7):1451-8.
1996: Hiroyasu Nakano; H Oshima; W Chung; L Williams-Abbott; Carl Ware; Hideo Yagita; K Okumura
TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor.
The Journal of biological chemistry 1996;271(25):14661-4.
1996: S Nuriya; Hideo Yagita; K Okumura; Miyuki Azuma
The differential role of CD86 and CD80 co-stimulatory molecules in the induction and the effector phases of contact hypersensitivity.
International immunology 1996;8(6):917-26.
1996: K Takazawa; Yasuyuki Hosoda; H Bashuda; K Seino; Hideo Yagita; T Tamatani; M Miyasaka; K Okumura
Synergistic effects of mycophenolate mofetil (MMF, RS-61443) and anti-LFA-1/ICAM-1 monoclonal antibodies on the prolongation of heart allograft survival in rats.
Transplantation proceedings 1996;28(3):1980-1.
1996: Yoshinori Seko; Osamu Sato; A Takagi; Yusuke Tada; Hisayuki Matsuo; Hideo Yagita; K Okumura; Y Yazaki
Restricted usage of T-cell receptor Valpha-Vbeta genes in infiltrating cells in aortic tissue of patients with Takayasu's arteritis.
Circulation 1996;93(10):1788-90.
1996: A Higashiyama; H Watanabe; K Okumura; Hideo Yagita
Involvement of tumor necrosis factor alpha and very late activation antigen 4/vascular cell adhesion molecule 1 interaction in surgical-stress-enhanced experimental metastasis.
Cancer immunology, immunotherapy : CII 1996;42(4):231-6.
1996: M Gotoh; Hiroki Ohzato; T Fukuzaki; Y Ohta; M Nishihara; Yasunori Hasuike; Koji Umeshita; Masato Sakon; Hideo Yagita; K Okumura; Masayuki Miyasaka; Morito Monden
Role of adhesion molecules in islet allo- and xenograft rejection.
Transplantation proceedings 1996;28(2):617.
1996: H Bashuda; K Seino; M Kano; K Sato; Miyuki Azuma; Hideo Yagita; K Okumura
Specific acceptance of cardiac allografts after treatment with antibodies to CD80 and CD86 in mice.
Transplantation proceedings 1996;28(2):1039-41.
1996: Yoshinori Seko; Y Enokawa; T Nakao; Hideo Yagita; K Okumura; Y Yazaki
Reduction of rat myocardial ischaemia/reperfusion injury by a synthetic selectin oligopeptide.
The Journal of pathology 1996;178(3):335-42.
1996: Yoshinori Seko; E Yoshifumi; Hideo Yagita; K Okumura; Y Yazaki
Restricted usage of T-cell receptor V alpha genes in infiltrating cells in murine hearts with acute myocarditis caused by coxsackie virus B3.
The Journal of pathology 1996;178(3):330-4.
1996: I Yonezawa; K Kato; Hideo Yagita; Y Yamauchi; K Okumura
VLA-5-mediated interaction with fibronectin induces cytokine production by human chondrocytes.
Biochemical and biophysical research communications 1996;219(1):261-5.
1996: Yoshifumi Kato; Atsuyuki Yamataka; Hideo Yagita; K Okumura; T Fujiwara; Takeshi Miyano
Specific acceptance of fetal bowel allograft in mice after combined treatment with anti-intercellular adhesion molecule-1 and leukocyte function-associated antigen-1 antibodies.
Annals of surgery 1996;223(1):94-100.
1995: M Hishii; T Nitta; H Ishida; M Ebato; A Kurosu; Hideo Yagita; K Sato; K Okumura
Human glioma-derived interleukin-10 inhibits antitumor immune responses in vitro.
Neurosurgery 1995;37(6):1160-6; discussion 1166-7.
1995: Nobuhiko Kayagaki; A Kawasaki; T Ebata; H Ohmoto; S Ikeda; S Inoue; K Yoshino; K Okumura; Hideo Yagita
Metalloproteinase-mediated release of human Fas ligand.
The Journal of experimental medicine 1995;182(6):1777-83.
1995: Atsuo Nakajima; Miyuki Azuma; Sanki Kodera; S Nuriya; A Terashi; Masaaki Abe; Sachiko Hirose; T Shirai; Hideo Yagita; K Okumura
Preferential dependence of autoantibody production in murine lupus on CD86 costimulatory molecule.
European journal of immunology 1995;25(11):3060-9.
1995: Yoshinori Seko; Masahiko Azuma; Hideo Yagita; K Okumura; H Hirai; Ryozo Nagai; Y Yazaki
Perforin-positive leukemic cell infiltration in the heart of a patient with T-cell prolymphocytic leukemia.
Internal medicine (Tokyo, Japan) 1995;34(8):782-4.
1995: Yoshinori Seko; Shigeru Ishiyama; Toshiro Nishikawa; T Kasajima; Michiaki Hiroe; N Kagawa; K Osada; Shin Suzuki; Hideo Yagita; K Okumura
Restricted usage of T cell receptor V alpha-V beta genes in infiltrating cells in the hearts of patients with acute myocarditis and dilated cardiomyopathy.
The Journal of clinical investigation 1995;96(2):1035-41.
1995: K Seino; Miyuki Azuma; H Bashuda; Katashi Fukao; Hideo Yagita; K Okumura
CD86 (B70/B7-2) on endothelial cells co-stimulates allogeneic CD4+ T cells.
International immunology 1995;7(8):1331-7.
1995: T Tanaka; Y Ohtsuka; Hideo Yagita; Y Shiratori; M Omata; K Okumura
Involvement of alpha 1 and alpha 4 integrins in gut mucosal injury of graft-versus-host disease.
International immunology 1995;7(8):1183-9.
1995: Yoshifumi Kato; Atsuyuki Yamataka; Hideo Yagita; H Bashuda; K Okumura; Takeshi Miyano
Prevention of fetal bowel allograft rejection by combined treatment with anti-ICAM-1 and anti-LFA-1 antibodies.
Journal of pediatric surgery 1995;30(7):1093-7.
1995: K Takazawa; Yasuyuki Hosoda; H Bashuda; Hideo Yagita; K Okumura; Y Kaneko
CAM--a novel immunosuppressive agent.
Transplantation 1995;59(12):1723-7.
1995: Kensho Noto; K Kato; K Okumura; Hideo Yagita
Identification and functional characterization of mouse CD29 with a mAb.
International immunology 1995;7(5):835-42.
1995: M Nishihara; M Gotoh; T Fukuzaki; Y Ohta; Morito Monden; Hideo Yagita; K Okumura; Masayuki Miyasaka; T Mori
Potent immunosuppressive effect of anti-LFA-1 monoclonal antibody on islet allograft rejection.
Transplantation proceedings 1995;27(1):372.
1995: Y Ohta; M Gotoh; T Fukuzaki; M Nishihara; Hideo Yagita; K Okumura; Masayuki Miyasaka; Morito Monden
Participation of donor adhesion molecules in islet xenograft rejection.
Transplantation proceedings 1995;27(1):256-7.
1995: M Yasuda; Y Hasunuma; H Adachi; C Sekine; T Sakanishi; Hiroshi Hashimoto; Chisei Ra; Hideo Yagita; K Okumura
Expression and function of fibronectin binding integrins on rat mast cells.
International immunology 1995;7(2):251-8.
1995: Y Iwanuma; K Kato; Hideo Yagita; K Okumura
Induction of tumor-specific cytotoxic T lymphocytes and natural killer cells by tumor cells transfected with the interleukin-2 gene.
Cancer immunology, immunotherapy : CII 1995;40(1):17-23.
1995: C Ra; M Yasuda; H Sagara; Hideo Yagita; K Okumura
The role of adhesion molecules in triggering effector phase of immune responses.
Allergy proceedings : the official journal of regional and state allergy societies 1995;16(1):39-41.
1994: M Ebato; T Nitta; Hideo Yagita; K Sato; K Okumura
Shared amino acid sequences in the ND beta N and N alpha regions of the T cell receptors of tumor-infiltrating lymphocytes within malignant glioma.
European journal of immunology 1994;24(12):2987-92.
1994: Chisei Ra; M Yasuda; Hideo Yagita; K Okumura
Fibronectin receptor integrins are involved in mast cell activation.
The Journal of allergy and clinical immunology 1994;94(3 Pt 2):625-8.
1994: S Miyake; T Sakurai; K Okumura; Hideo Yagita
Identification of collagen and laminin receptor integrins on murine T lymphocytes.
European journal of immunology 1994;24(9):2000-5.
1994: H Okahara; Hideo Yagita; K Miyake; K Okumura
Involvement of very late activation antigen 4 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) in tumor necrosis factor alpha enhancement of experimental metastasis.
Cancer research 1994;54(12):3233-6.
1994: Y Hasegawa; Koichi Yokono; T Taki; K Amano; Y Tominaga; R Yoneda; N Yagi; S Maeda; Hideo Yagita; K Okumura
Prevention of autoimmune insulin-dependent diabetes in non-obese diabetic mice by anti-LFA-1 and anti-ICAM-1 mAb.
International immunology 1994;6(6):831-8.
1994: T Fukuzaki; M Gotoh; Morito Monden; Y Ohta; Keizo Dono; T Kanai; Hideo Yagita; K Okumura; Masayuki Miyasaka; T Mori
Role of adhesion molecules in islet xenograft rejection.
Transplantation proceedings 1994;26(3):1113.
1994: S Hanabuchi; M Koyanagi; A Kawasaki; N Shinohara; A Matsuzawa; Y Nishimura; Y Kobayashi; S Yonehara; Hideo Yagita; K Okumura
Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):4930-4.
1994: Yoshinori Seko; Hideo Yagita; K Okumura; Y Yazaki
T-cell receptor V beta gene expression in infiltrating cells in murine hearts with acute myocarditis caused by coxsackievirus B3.
Circulation 1994;89(5):2170-5.
1994: Yasuko Tsunetsugu-Yokota; T Mizuochi; H Hashimoto; A Szikaradkiewicz; Hideo Yagita; A Yano; Toshitada Takemori
Analysis of function of a human antigen-presenting cell by xenogeneic interaction with mouse T cells.
Immunology letters 1994;40(1):73-7.
1994: Yoshinori Seko; S Minota; A Kawasaki; Y Shinkai; K Maeda; Hideo Yagita; K Okumura; Osamu Sato; A Takagi; Yusuke Tada
Perforin-secreting killer cell infiltration and expression of a 65-kD heat-shock protein in aortic tissue of patients with Takayasu's arteritis.
The Journal of clinical investigation 1994;93(2):750-8.
1994: M Gotoh; T Fukuzaki; Morito Monden; Keizo Dono; T Kanai; Hideo Yagita; K Okumura; T Mori
A potential immunosuppressive effect of anti-lymphocyte function-associated antigen-1 monoclonal antibody on islet transplantation.
Transplantation 1994;57(1):123-6.
1993: M Ebato; T Nitta; Hideo Yagita; K Sato; K Okumura
Skewed distribution of TCR V alpha 7-bearing T cells within tumor-infiltrating lymphocytes of HLA-A24(9)-positive patients with malignant glioma.
Immunology letters 1993;39(1):53-64.
1993: Miyuki Azuma; D Ito; Hideo Yagita; K Okumura; Joseph H Phillips; Lewis L Lanier; C Somoza
B70 antigen is a second ligand for CTLA-4 and CD28.
Nature 1993;366(6450):76-9.
1993: N Uemura; Keiya Ozawa; K Takahashi; Arinobu Tojo; Kenzaburo Tani; Kenichi Harigaya; S Suzu; K Motoyoshi; H Matsuda; Hideo Yagita
Binding of membrane-anchored macrophage colony-stimulating factor (M-CSF) to its receptor mediates specific adhesion between stromal cells and M-CSF receptor-bearing hematopoietic cells.
Blood 1993;82(9):2634-40.
1993: T Yamataka; Hiroyuki Kobayashi; Hideo Yagita; K Okumura; T Tamatani; M Miyasaka
The effect of anti-ICAM-1 monoclonal antibody treatment on the transplantation of the small bowel in rats.
Journal of pediatric surgery 1993;28(11):1451-7.
1993: Hiroyuki Kobayashi; Takeshi Miyano; Atsuyuki Yamataka; T Yamataka; Hideo Yagita; H Eto; Y Ligo; S Tansyo; Y Kojima; T Tamatani
Prolongation of rat cardiac allograft survival by a monoclonal antibody: anti-rat intercellular adhesion molecule-1.
Cardiovascular surgery (London, England) 1993;1(5):577-82.
1993: T Yamazaki; Y Seko; T Tamatani; M Miyasaka; Hideo Yagita; K Okumura; R Nagai; Y Yazaki
Expression of intercellular adhesion molecule-1 in rat heart with ischemia/reperfusion and limitation of infarct size by treatment with antibodies against cell adhesion molecules.
The American journal of pathology 1993;143(2):410-8.
1993: K Kato; N Tamura; K Okumura; Hideo Yagita
Identification of the T cell surface signal-transducing glycoprotein sgp-60 as CD48, a counter-receptor for mouse CD2.
European journal of immunology 1993;23(6):1412-5.
1993: Yoshinori Seko; Y Shinkai; A Kawasaki; Hideo Yagita; K Okumura; Y Yazaki
Evidence of perforin-mediated cardiac myocyte injury in acute murine myocarditis caused by Coxsackie virus B3.
The Journal of pathology 1993;170(1):53-8.
1993: Yoshinori Seko; H Matsuda; K Kato; Y Hashimoto; Hideo Yagita; K Okumura; Y Yazaki
Expression of intercellular adhesion molecule-1 in murine hearts with acute myocarditis caused by coxsackievirus B3.
The Journal of clinical investigation 1993;91(4):1327-36.
1993: S Miyake; Hideo Yagita; T Maruyama; H Hashimoto; N Miyasaka; K Okumura
Beta 1 integrin-mediated interaction with extracellular matrix proteins regulates cytokine gene expression in synovial fluid cells of rheumatoid arthritis patients.
The Journal of experimental medicine 1993;177(3):863-8.
1993: M Gotoh; T Fukuzaki; Keizo Dono; H Wada; T Kanai; Morito Monden; Hideo Yagita; K Okumura; T Mori
Induction of unresponsiveness to islet allograft by anti-LFA-1 monoclonal antibody treatment.
Transplantation proceedings 1993;25(1 Pt 2):973-4.
1992: Y Takeuchi; Toshiyuki Tanaka; K Hamamura; T Sugimoto; Masayuki Miyasaka; Hideo Yagita; K Okumura
Expression and role of interleukin-2 receptor beta chain on CD4-CD8- T cell receptor alpha beta+ cells [corrected].
European journal of immunology 1992;22(11):2929-35.
1992: K Kato; M Koyanagi; H Okada; T Takanashi; Y W Wong; A F Williams; K Okumura; Hideo Yagita
CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.
The Journal of experimental medicine 1992;176(5):1241-9.
1992: T Minamizuka; H Eto; M Nakata; Hideo Yagita; K Okumura
Effect of immunization with anti-idiotypic antibody to melanoma antigen on lung metastasis in mice.
Nihon geka hokan. Archiv für japanische Chirurgie 1992;61(6):413-22.
1992: Yoshinori Seko; T Yamazaki; Y Shinkai; Hideo Yagita; K Okumura; S Naito; K Imataka; J Fujii; Y Yazaki
Cellular and molecular bases for the immunopathology of the myocardial cell damage involved in acute viral myocarditis with special reference to dilated cardiomyopathy.
Japanese circulation journal 1992;56(10):1062-72.
1992: M Nakata; A Kawasaki; Miyuki Azuma; K Tsuji; H Matsuda; Y Shinkai; Hideo Yagita; K Okumura
Expression of perforin and cytolytic potential of human peripheral blood lymphocyte subpopulations.
International immunology 1992;4(9):1049-54.
1992: T Nitta; Hideo Yagita; K Sato; K Okumura
Expression of Fc gamma receptors on astroglial cell lines and their role in the central nervous system.
Neurosurgery 1992;31(1):83-7; discussion 87-8.
1992: K Takahashi; M Nakata; Toshiyuki Tanaka; H Adachi; H Nakauchi; Hideo Yagita; K Okumura
CD4 and CD8 regulate interleukin 2 responses of T cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(12):5557-61.
1992: A Kawasaki; Y Shinkai; Hideo Yagita; K Okumura
Expression of perforin in murine natural killer cells and cytotoxic T lymphocytes in vivo.
European journal of immunology 1992;22(5):1215-9.
1992: Y Ota; T Kobata; M Seki; Hideo Yagita; S Shimada; Y Y Huang; Yohtaroh Takagaki; K Okumura
Extrathymic origin of V gamma 1/V delta 6 T cells in the skin.
European journal of immunology 1992;22(2):595-8.
1992: Hideo Yagita; M Nakata; A Kawasaki; Y Shinkai; K Okumura
Role of perforin in lymphocyte-mediated cytolysis.
Advances in immunology 1992;51():215-42.
1991: Yoshinori Seko; Y Shinkai; A Kawasaki; Hideo Yagita; K Okumura; F Takaku; Y Yazaki
Expression of perforin in infiltrating cells in murine hearts with acute myocarditis caused by coxsackievirus B3.
Circulation 1991;84(2):788-95.
1991: K Takahashi; T Nakamura; H Adachi; Hideo Yagita; K Okumura
Antigen-independent T cell activation mediated by a very late activation antigen-like extracellular matrix receptor.
European journal of immunology 1991;21(6):1559-62.
1991: T Nitta; M Nakata; Hideo Yagita; K Okumura
Interleukin-2 activated T cells (T-LAK) express CD16 antigen and are triggered to target cell lysis by bispecific antibody.
Immunology letters 1991;28(1):31-7.
1991: T Nitta; Hideo Yagita; K Sato; K Okumura
Surrogate receptor-mediated cellular cytotoxicity against malignant human glioma cells.
Neurosurgery 1991;28(3):394-9.
1991: T Nakamura; K Takahashi; M Koyanagi; Hideo Yagita; K Okumura
Activation of a natural killer clone upon target cell binding via CD2.
European journal of immunology 1991;21(3):831-4.
1990: K Takahashi; T Nakamura; M Koyanagi; K Kato; Y Hashimoto; Hideo Yagita; K Okumura
A murine very late activation antigen-like extracellular matrix receptor involved in CD2- and lymphocyte function-associated antigen-1-independent killer-target cell interaction.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(12):4371-9.
1990: M Nakata; M J Smyth; Y Norihisa; A Kawasaki; Y Shinkai; K Okumura; Hideo Yagita
Constitutive expression of pore-forming protein in peripheral blood gamma/delta T cells: implication for their cytotoxic role in vivo.
The Journal of experimental medicine 1990;172(6):1877-80.
1990: T Nakamura; K Takahashi; T Fukazawa; M Koyanagi; A Yokoyama; H Kato; Hideo Yagita; K Okumura
Relative contribution of CD2 and LFA-1 to murine T and natural killer cell functions.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(11):3628-34.
1990: T Nitta; A Ishizawa; M Ito; K Sato; Hideo Yagita; K Kumura
[Induction of cytotoxicity from human lymphocytes coated with bispecific antibody against human glioma cells].
No shinkei geka. Neurological surgery 1990;18(11):1001-6.
1990: T Sato; H Tamauchi; Hideo Yagita; Y Arat; K Okumura; S Habu
Dissociation of signal transduction via Thy-1 and CD3 antigens in murine T cells.
Immunology letters 1990;26(1):99-103.
1990: T Nitta; Hideo Yagita; K Okumura; K Sato
[Analysis of receptor expression on astrocytic cells].
Nō to shinkei = Brain and nerve 1990;42(10):945-50.
1990: T Kobata; Hideo Yagita; H Matsuda; M Seki; Y Ota; M Katagiri; K Okumura
Expression and function of a 90-kilodalton homodimeric molecule (10D1 antigen) on human thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(4):1053-8.
1990: T Shirai; Masaaki Abe; Hideo Yagita; K Okumura; Herbert C Morse; W F Davidson
The expanded populations of CD4-CD8- T cell receptor alpha/beta+ T cells associated with the lpr and gld mutations are CD2-.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(10):3756-61.
1990: T Nitta; K Sato; Hideo Yagita; K Okumura; S Ishii
Preliminary trial of specific targeting therapy against malignant glioma.
Lancet 1990;335(8686):368-71.
1990: T Kobata; Hideo Yagita; H Matsuda; S Tansyo; Hidetaka Yakura; M Katagiri; K Okumura
A novel homodimeric molecule involved in human T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(3):830-5.
1990: A Kawasaki; Y Shinkai; Y Kuwana; Akiko Furuya; Y Iigo; Nobuo Hanai; S Itoh; Hideo Yagita; K Okumura
Perforin, a pore-forming protein detectable by monoclonal antibodies, is a functional marker for killer cells.
International immunology 1990;2(7):677-84.
1990: T Kobata; Y Shinkai; Y Iigo; A Kawasaki; Hideo Yagita; S Ito; S Shimada; S I Katz; K Okumura
Thy-1-positive dendritic epidermal cells contain a killer protein perforin.
International immunology 1990;2(11):1113-6.
1989: Hideo Yagita; J Asakawa; S Tansyo; T Nakamura; S Habu; K Okumura
Expression and function of CD2 during murine thymocyte ontogeny.
European journal of immunology 1989;19(12):2211-7.
1989: H Ishikawa; Y Shinkai; Hideo Yagita; C C Yue; Pierre A Henkart; S Sawada; H A Young; C W Reynolds; K Okumura
Molecular cloning of rat cytolysin.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(9):3069-73.
1989: T Nitta; Hideo Yagita; K Sato; K Okumura
Involvement of CD56 (NKH-1/Leu-19 antigen) as an adhesion molecule in natural killer-target cell interaction.
The Journal of experimental medicine 1989;170(5):1757-61.
1989: Hideo Yagita; M Nakata; A Azuma; T Nitta; T Takeshita; K Sugamura; K Okumura
Activation of peripheral blood T cells via the p75 interleukin 2 receptor.
The Journal of experimental medicine 1989;170(4):1445-50.
1989: T Nitta; Hideo Yagita; T Azuma; K Sato; K Okumura
Bispecific F (ab')2 monomer prepared with anti-CD3 and anti-tumor monoclonal antibodies is most potent in induction of cytolysis of human T cells.
European journal of immunology 1989;19(8):1437-41.
1989: Y Shinkai; M C Yoshida; K Maeda; T Kobata; K Maruyama; J Yodoi; Hideo Yagita; K Okumura
Molecular cloning and chromosomal assignment of a human perforin (PFP) gene.
Immunogenetics 1989;30(6):452-7.
1989: Hideo Yagita; T Nakamura; J Asakawa; H Matsuda; S Tansyo; Y Iigo; K Okumura
CD2 expression in murine B cell lineage.
International immunology 1989;1(1):94-8.
1989: Yoshiaki Tokano; S Arai; Hiroshi Hashimoto; Sachiko Hirose; Hideo Yagita; H Nakauchi; Y Kumagai; Y Arata; K Okumura
The distinct subgroup of patients with rheumatoid arthritis shown by Ig G3-reactive rheumatoid factor.
Autoimmunity 1989;5(1-2):107-14.
1989: Hideo Yagita; T Nakamura; H Karasuyama; K Okumura
Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(2):645-9.
1988: K Yamamoto; K Ono; K Nakahara; K Kitamura; Hideo Yagita; K Okumura
Characterization of a monoclonal antibody reacting with a neutral glycolipid that is associated with human T-cell leukemia virus type I infection and freshly isolated adult T-cell leukemia.
Cancer research 1988;48(11):3148-52.
1988: Hideo Yagita; K Okumura; H Nakauchi
Molecular cloning of the murine homologue of CD2. Homology of the molecule to its human counterpart T11.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(4):1321-6.
1988: Takao Hirano; Hiroaki Miyajima; H Kitagawa; N Watanabe; M Azuma; O Taniguchi; Hiroshi Hashimoto; Sachiko Hirose; Hideo Yagita; S Furusawa
Studies on murine IgE with monoclonal antibodies. I. Characterization of rat monoclonal anti-IgE antibodies and the use of these antibodies for determinations of serum IgE levels and for anaphylactic reactions.
International archives of allergy and applied immunology 1988;85(1):47-54.
1988: Yoshiaki Tokano; Hideo Yagita; N Iida; Hiroshi Hashimoto; K Okumura; Sachiko Hirose
Relation between the level of IgG subclasses and infections in patients with systemic lupus erythematosus.
International archives of allergy and applied immunology 1988;87(1):55-8.
1987: Miyuki Azuma; Takao Hirano; Hiroaki Miyajima; N Watanabe; Hideo Yagita; S Enomoto; S Furusawa; Z Ovary; T Kinashi; T Honjo
Regulation of murine IgE production in SJA/9 and nude mice. Potentiation of IgE production by recombinant interleukin 4.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(8):2538-44.
1987: H Nakauchi; H Osada; Hideo Yagita; K Okumura
Molecular evidence that SJL reticulum cell sarcomas are derived from pre-B cell. Clonal rearrangement of heavy chain but not of light chain immunoglobulin genes.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(8):2803-9.