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Paola Briata

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Matteo Giovarelli; Michela Pasero; Gabriele Bucci; Roberto Gherzi; Paola Briata
KSRP silencing favors neural differentiation of P19 teratocarcinoma cells.
Giuseppe Nicastro; Paola Briata; María Flor García-Mayoral; Roberto Gherzi; David Hollingworth; Geoff Kelly; Stephen R Martin; Andres Ramos
Noncanonical G recognition mediates KSRP regulation of let-7 biogenesis.
Michela Pasero; gabriele bucci; Roberto Gherzi; Matteo Giovarelli; Paola Briata
Bone morphogenetic protein/SMAD signaling orients cell fate decision by impairing KSRP-dependent microRNA maturation.

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All Publications

2013: Matteo Giovarelli; Michela Pasero; Gabriele Bucci; Roberto Gherzi; Paola Briata
KSRP silencing favors neural differentiation of P19 teratocarcinoma cells.
Biochimica et biophysica acta 2013;1829(5):469-79.
2012: Giuseppe Nicastro; Paola Briata; María Flor García-Mayoral; Roberto Gherzi; David Hollingworth; Geoff Kelly; Stephen R Martin; Andres Ramos
Noncanonical G recognition mediates KSRP regulation of let-7 biogenesis.
Nature structural & molecular biology 2012;19(12):1282-6.
2012: Michela Pasero; gabriele bucci; Roberto Gherzi; Matteo Giovarelli; Paola Briata
Bone morphogenetic protein/SMAD signaling orients cell fate decision by impairing KSRP-dependent microRNA maturation.
Cell reports 2012;2(5):1159-68.
2012: David Hollingworth; Stephen R Martin; Giuseppe Nicastro; Paola Briata; Adela M Candel; Roberto Gherzi; Andres Ramos
KH domains with impaired nucleic acid binding as a tool for functional analysis.
Nucleic acids research 2012;40(14):6873-86.
2012: Paola Briata; C-Y Chen; C-F Chou; M Giovarelli; W-J Lin; M Pasero; M G Rosenfeld; M Trabucchi; Roberto Gherzi
PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis.
Cell death and differentiation 2012;19(3):478-87.
2012: Emanuela Repetto; Michael G Rosenfeld; Paola Briata; Roberto Gherzi; Brian D Harfe; Nathalie Kuziner; Michael McManus; Michele Trabucchi
Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP.
PLoS genetics 2012;8(7):e1002823.
2011: Annapina Russo; Paola Briata; Morena Catillo; Davide Esposito; Concetta Pietropaolo; Giulia Russo
Autoregulatory circuit of human rpL3 expression requires hnRNP H1, NPM and KHSRP.
Nucleic acids research 2011;39(17):7576-85.
2011: Paola Briata; Ching-Yi Chen; Matteo Giovarelli; Michela Pasero; Michele Trabucchi; Andres Ramos; Roberto Gherzi
KSRP, many functions for a single protein.
Frontiers in bioscience : a journal and virtual library 2011;16():1787-96.
2010: Roberto Gherzi; Andres Ramos; Michele Trabucchi; Ching-Yi Chen; Paola Briata
The role of KSRP in mRNA decay and microRNA precursor maturation.
Wiley interdisciplinary reviews. RNA 2010;1(2):230-9.
2010: Irene Díaz-Moreno; David Hollingworth; Geoff Kelly; Stephen Martin; MaríaFlor García-Mayoral; Paola Briata; Roberto Gherzi; Andres Ramos
Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets.
Nucleic acids research 2010;38(15):5193-205.
2010: Roberto Gherzi; M Trabucchi; Marco Ponassi; I-E Gallouzi; M G Rosenfeld; Paola Briata
Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation.
Cell death and differentiation 2010;17(6):975-83.
2010: Michele Trabucchi; Paola Briata; Witold Filipowicz; Andres Ramos; Roberto Gherzi; Michael G Rosenfeld
KSRP promotes the maturation of a group of miRNA precursors.
Advances in experimental medicine and biology 2010;700():36-42.
2009: Michele Trabucchi; Paola Briata; Witold Filipowicz; Michael G Rosenfeld; Andres Ramos; Roberto Gherzi
How to control miRNA maturation?
RNA biology 2009;6(5):536-40.
2009: Tina Ruggiero; Michele Trabucchi; Francesca De Santa; Simona Zupo; Brian D Harfe; Michael McManus; M Geoff Rosenfeld; Paola Briata; Roberto Gherzi
LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(9):2898-908.
2009: Michele Trabucchi; Paola Briata; Mariaflor Garcia-Mayoral; Astrid D Haase; Witold Filipowicz; Andres Ramos; Roberto Gherzi; Michael G Rosenfeld
The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs.
Nature 2009;459(7249):1010-4.
2009: Irene Díaz-Moreno; David Hollingworth; Thomas A Frenkiel; Geoff Kelly; Stephen Martin; Steven Howell; MaríaFlor García-Mayoral; Roberto Gherzi; Paola Briata; Andres Ramos
Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding.
Nature structural & molecular biology 2009;16(3):238-46.
2009: Morris Nechama; Yong Peng; Osnat Bell; Paola Briata; Roberto Gherzi; Daniel R Schoenberg; Tally Naveh-Many
KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells.
BMC cell biology 2009;10():70.
2008: Morris Nechama; Iddo Z Ben-Dov; Paola Briata; Roberto Gherzi; Tally Naveh-Many
The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(10):3458-68.
2007: Tina Ruggiero; Michele Trabucchi; Marco Ponassi; Giorgio Corte; Ching-Yi Chen; Latifa al-Haj; Khalid S A Khabar; Paola Briata; Roberto Gherzi
Identification of a set of KSRP target transcripts upregulated by PI3K-AKT signaling.
BMC molecular biology 2007;8():28.
2006: Roberto Gherzi; Michele Trabucchi; Marco Ponassi; Tina Ruggiero; Giorgio Corte; Christoph Moroni; Ching-Yi Chen; Khalid S A Khabar; Jens S Andersen; Paola Briata
The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling.
PLoS biology 2006;5(1):e5.
2005: Paola Briata; Sonia Vanina Forcales; Marco Ponassi; Giorgio Corte; Ching-Yi Chen; Michael Karin; Pier Lorenzo Puri; Roberto Gherzi
p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts.
Molecular cell 2005;20(6):891-903.
2004: Roberto Gherzi; Kyung-Yeol Lee; Paola Briata; Daniel Wegmüller; Christoph Moroni; Michael Karin; Ching-Yi Chen
A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery.
Molecular cell 2004;14(5):571-83.
2003: Paola Briata; Cristina Ilengo; Giorgio Corte; Christoph Moroni; Michael G Rosenfeld; Ching-Yi Chen; Roberto Gherzi
The Wnt/beta-catenin-->Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs.
Molecular cell 2003;12(5):1201-11.
2003: Sung Hee Baek; Chrissa Kioussi; Paola Briata; Degeng Wang; H D Nguyen; Kenneth A Ohgi; Christopher K Glass; Anthony Wynshaw-Boris; David W Rose; Michael G Rosenfeld
Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3245-50.
2002: Chrissa Kioussi; Paola Briata; Sung Hee Baek; David W Rose; Natasha S Hamblet; Thomas Herman; Kenneth A Ohgi; Chijen Lin; Anatoli Gleiberman; Jianbo Wang; Véronique Brault; Pilar Ruiz-Lozano; H D Nguyen; Rolf Kemler; Christopher K Glass; Anthony Wynshaw-Boris; Michael G Rosenfeld
Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development.
Cell 2002;111(5):673-85.
2002: Chrissa Kioussi; Paola Briata; Sung Hee Baek; Anthony Wynshaw-Boris; David W Rose; Michael G Rosenfeld
Pitx genes during cardiovascular development.
Cold Spring Harbor symposia on quantitative biology 2002;67():81-7.
2000: Michael G Rosenfeld; Paola Briata; Jeremy S Dasen; Anatoli Gleiberman; Chrissa Kioussi; C Lin; SM O'Connell; A Ryan; DP Szeto; M Treier
Multistep signaling and transcriptional requirements for pituitary organogenesis in vivo.
Recent progress in hormone research 2000;55():1-13; discussion 13-4.
1999: Chijen Lin; Chrissa Kioussi; SM O'Connell; Paola Briata; DP Szeto; Forrest Liu; Juan Carlos Izpisúa Belmonte; Michael G Rosenfeld
Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis.
Nature 1999;401(6750):279-82.
1999: N Bobola; Paola Briata; Cristina Ilengo; Nadia Rosatto; C Craft; Giorgio Corte; Roberto Ravazzolo
OTX2 homeodomain protein binds a DNA element necessary for interphotoreceptor retinoid binding protein gene expression.
Mechanisms of development 1999;82(1-2):165-9.
1999: Paola Briata; Cristina Ilengo; N Bobola; Giorgio Corte
Binding properties of the human homeodomain protein OTX2 to a DNA target sequence.
FEBS letters 1999;445(1):160-4.
1998: Dario Acampora; V Avantaggiato; Francesca Tuorto; Paola Briata; Giorgio Corte; Antonio Simeone
Visceral endoderm-restricted translation of Otx1 mediates recovery of Otx2 requirements for specification of anterior neural plate and normal gastrulation.
Development (Cambridge, England) 1998;125(24):5091-104.
1998: Antonello Mallamaci; R Iannone; Paola Briata; L Pintonello; Sara Mercurio; Edoardo Boncinelli; Giorgio Corte
EMX2 protein in the developing mouse brain and olfactory area.
Mechanisms of development 1998;77(2):165-72.
1997: P Bovolenta; Antonello Mallamaci; Paola Briata; Giorgio Corte; Edoardo Boncinelli
Implication of OTX2 in pigment epithelium determination and neural retina differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(11):4243-52.
1997: Roberto Gherzi; Paola Briata; Edoardo Boncinelli; Marco Ponassi; G Querzè; Francesca Viti; Giorgio Corte; Luciano Zardi
The human homeodomain protein OTX2 binds to the human tenascin-C promoter and trans-represses its activity in transfected cells.
DNA and cell biology 1997;16(5):559-67.
1997: Paola Briata; Cristina Ilengo; R Van DeWerken; Giorgio Corte
Mapping of a potent transcriptional repression region of the human homeodomain protein EVX1.
FEBS letters 1997;402(2-3):131-5.
1996: Antonello Mallamaci; E Di Blas; Paola Briata; Edoardo Boncinelli; Giorgio Corte
OTX2 homeoprotein in the developing central nervous system and migratory cells of the olfactory area.
Mechanisms of development 1996;58(1-2):165-78.
1996: Paola Briata; E Di Blas; Massimo Gulisano; Antonello Mallamaci; R Iannone; Edoardo Boncinelli; Giorgio Corte
EMX1 homeoprotein is expressed in cell nuclei of the developing cerebral cortex and in the axons of the olfactory sensory neurons.
Mechanisms of development 1996;57(2):169-80.
1995: Paola Briata; R Van De Werken; I Airoldi; Cristina Ilengo; E Di Blas; Edoardo Boncinelli; Giorgio Corte
Transcriptional repression by the human homeobox protein EVX1 in transfected mammalian cells.
The Journal of biological chemistry 1995;270(46):27695-701.
1994: Roberto Gherzi; Paola Briata; Hans-Christoph Fehmann; Burkhard Göke
Ras antagonizes cAMP stimulated glucagon gene transcription in pancreatic islet cell lines.
FEBS letters 1994;353(3):277-80.
1993: Paola Briata; F D'Anna; A T Franzi; Roberto Gherzi
AP-1 activity during normal human keratinocyte differentiation: evidence for a cytosolic modulator of AP-1/DNA binding.
Experimental cell research 1993;204(1):136-46.
1993: Roberto Gherzi; Paola Briata
[Insulin receptors, mechanism of signal transduction. Examples of abnormalities in states of insulin resistance].
Journées annuelles de diabétologie de l'Hôtel-Dieu 1993;():11-21.
1993: Giorgio Corte; I Airoldi; Paola Briata; M T Corsetti; Antonio Daga; A Massa; L Sanseverino; F Lancia
The homeotic gene products in the control of cell differentiation and proliferation.
Cancer detection and prevention 1993;17(2):261-6.
1992: M T Corsetti; Paola Briata; L Sanseverino; Antonio Daga; I Airoldi; A Simeone; G Palmisano; C Angelini; Edoardo Boncinelli; Giorgio Corte
Differential DNA binding properties of three human homeodomain proteins.
Nucleic acids research 1992;20(17):4465-72.
1992: Giorgio Sesti; MA Marini; Paola Briata; A N Tullio; A Montemurro; P Borboni; R De Pirro; Roberto Gherzi; Renato Lauro
Androgens increase insulin receptor mRNA levels, insulin binding, and insulin responsiveness in HEp-2 larynx carcinoma cells.
Molecular and cellular endocrinology 1992;86(1-2):111-8.
1992: Roberto Gherzi; B Sparatore; M Patrone; A Sciutto; Paola Briata
Protein kinase C mRNA levels and activity in reconstituted normal human epidermis: relationships to cell differentiation.
Biochemical and biophysical research communications 1992;184(1):283-91.
1991: Paola Briata; C Bellini; Marina Vignolo; Roberto Gherzi
Insulin receptor gene expression is reduced in cells from a progeric patient.
Molecular and cellular endocrinology 1991;75(1):9-14.
1990: Paola Briata; Roberto Gherzi
Multifactorial control of insulin receptor gene expression in human cell lines.
Biochemical and biophysical research communications 1990;170(3):1184-90.
1990: Paola Briata; L Briata; Roberto Gherzi
Glucose starvation and glycosylation inhibitors reduce insulin receptor gene expression: characterization and potential mechanism in human cells.
Biochemical and biophysical research communications 1990;169(2):397-405.
1989: Paola Briata; C Laurino; Roberto Gherzi
c-myc gene expression in human cells is controlled by glucose.
Biochemical and biophysical research communications 1989;165(3):1123-9.
1989: Paola Briata; Roberto Gherzi; L Adezati; Renzo Cordera
Effect of two different glucose concentrations on insulin receptor mRNA levels in human hepatoma HepG2 cells.
Biochemical and biophysical research communications 1989;160(3):1415-20.
1986: F Chiarella; G L Viviani; P Bellotti; Paola Briata; S Domenicucci; G Carta; L Adezati; C Vecchio
[Left ventricular diastolic function in type I diabetes. A longitudinal echocardiographic study].
Giornale italiano di cardiologia 1986;16(7):544-50.