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Haruki Yamada
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48
Kiyohara, Hiroaki
24
Matsumoto, T
15
Cyong, Jong-Chol
5
Tomimori, Tsuyoshi
4
Aburada, Masaki
4
Sakurai, Masumi
3
Nagai, Takayuki
3
Nagai, T
2
Hisha, Hiroko
2
Ikehara, Susumu
2
Shirahata, Tatsuya
2
Sunazuka, Toshiaki
1
Kuwajima, Isao
1
Yasumizu, Ryoji
1
Yu, C
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All Publications
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2010: Kiyohara Hiroaki; Uchida Taichi; Takakiwa Manami; Matsuzaki Toshiake; Hada Noriyasu; Takeda Tadahiro; Shibata Toshiro; Yamada Haruki
Different contributions of side-chains in beta-D-(1-->3,6)-galactans on intestinal Peyer's patch-immunomodulation by polysaccharides from Astragalus mongholics Bunge.
Phytochemistry 2010;71(2-3):280-93.
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2003: Yabe T; Tuchida H; Kiyohara H; Takeda T; Yamada H
Induction of NGF synthesis in astrocytes by onjisaponins of Polygala tenuifolia, constituents of kampo (Japanese herbal) medicine, Ninjin-yoei-to.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2003;10(2-3):106-14.
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2003: Shirahata Tatsuya; Sunazuka Toshiaki; Yoshida Kiminari; Yamamoto Daisuke; Harigaya Yoshihiko; Nagai Takayuki; Kiyohara Hiroaki; Yamada Haruki; Kuwajima Isao; Omura Satoshi
Total synthesis and adjuvant activity of all stereoisomers of pinellic acid.
Bioorganic & medicinal chemistry letters 2003;13(5):937-41.
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2002: Nagai Takayuki; Kiyohara Hiroaki; Munakata Kaori; Shirahata Tatsuya; Sunazuka Toshiaki; Harigaya Yoshihiro; Yamada Haruki
Pinellic acid from the tuber of Pinellia ternata Breitenbach as an effective oral adjuvant for nasal influenza vaccine.
International immunopharmacology 2002;2(8):1183-93.
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2002: Sakurai Masumi H; Kiyohara Hiroaki; Nakahara Yasuo; Okamoto Koji; Yamada Haruki
Galactose-containing polysaccharides from Dictyostelium mucoroides as possible acceptor molecules for cell-type specific galactosyl transferase.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2002;132(3):541-9.
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2001: Nagai T; Suzuki Y; Kiyohara H; Susa E; Kato T; Nagamine T; Hagiwara Y; Tamura S; Yabe T; Aizawa C; Yamada H
Onjisaponins, from the root of Polygala tenuifolia Willdenow, as effective adjuvants for nasal influenza and diphtheria-pertussis-tetanus vaccines.
Vaccine 2001;19(32):4824-34.
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2000: Guo Y; Matsumoto T; Kikuchi Y; Ikejima T; Wang B; Yamada H
Effects of a pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. on interleukin 6 production of murine B cells and B cell lines.
Immunopharmacology 2000;49(3):307-16.
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2000: Kiyohara H; Matsumoto T; Yamada H
Lignin-carbohydrate complexes: intestinal immune system modulating ingredients in kampo (Japanese herbal) medicine, juzen-taiho-to.
Planta medica 2000;66(1):20-4.
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2000: Matsumoto T; Sakurai M H; Kiyohara H; Yamada H
Orally administered decoction of Kampo (Japanese herbal) medicine, "Juzen-Taiho-To" modulates cytokine secretion and induces NKT cells in mouse liver.
Immunopharmacology 2000;46(2):149-61.
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2000: Matsumoto T; Yamada H
Orally administered Kampo (Japanese herbal) medicine, "Juzen-Taiho-To" modulates cytokine secretion in gut associated lymphoreticular tissues in mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2000;6(6):425-30.
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1999: Sakurai M H; Matsumoto T; Kiyohara H; Yamada H
B-cell proliferation activity of pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. and its structural requirement.
Immunology 1999;97(3):540-7.
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1998: Yu K W; Kiyohara H; Matsumoto T; Yang H C; Yamada H
Intestinal immune system modulating polysaccharides from rhizomes of Atractylodes lancea.
Planta medica 1998;64(8):714-9.
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1998: Sakurai M H; Kiyohara H; Matsumoto T; Tsumuraya Y; Hashimoto Y; Yamada H
Characterization of antigenic epitopes in anti-ulcer pectic polysaccharides from Bupleurum falcatum L. using several carbohydrases.
Carbohydrate research 1998;311(4):219-29.
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1998: Nagai T; Yamada H
In vivo anti-influenza virus activity of Kampo (Japanese herbal) medicine "sho-seiryu-to"--stimulation of mucosal immune system and effect on allergic pulmonary inflammation model mice.
Immunopharmacology and immunotoxicology 1998;20(2):267-81.
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1998: Yamada H; Nagai T
In vivo antiinfluenza virus activity of Kampo medicine Sho-seiryu-to through mucosal immune system.
Methods and findings in experimental and clinical pharmacology 1998;20(3):185-92.
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1997: Nagai T; Nishibe Y; Makino Y; Tomimori T; Yamada H
Enhancement of in vivo anti-influenza virus activity of 5,7,4'-trihydroxy-8-methoxyflavone by drug delivery system using hydroxypropyl cellulose.
Biological & pharmaceutical bulletin 1997;20(10):1082-5.
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1997: Zhang Y; Kiyohara H; Matsumoto T; Yamada H
Fractionation and chemical properties of immunomodulating polysaccharides from roots of Dipsacus asperoides.
Planta medica 1997;63(5):393-9.
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1997: Hisha H; Yamada H; Sakurai M H; Kiyohara H; Li Y; Yu C; Takemoto N; Kawamura H; Yamaura K; Shinohara S; Komatsu Y; Aburada M; Ikehara S
Isolation and identification of hematopoietic stem cell-stimulating substances from Kampo (Japanese herbal) medicine, Juzen-taiho-to.
Blood 1997;90(3):1022-30.
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1997: Shin K S; Kiyohara H; Matsumoto T; Yamada H
Rhamnogalacturonan II from the leaves of Panax ginseng C.A. Meyer as a macrophage Fc receptor expression-enhancing polysaccharide.
Carbohydrate research 1997;300(3):239-49.
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1996: Sakurai M H; Matsumoto T; Kiyohara H; Yamada H
Detection and tissue distribution of anti-ulcer pectic polysaccharides from Bupleurum falcatum by polyclonal antibody.
Planta medica 1996;62(4):341-6.
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1996: Matsumoto T; Tanaka M; Yamada H; Cyong J C
Effect of licorice roots on carrageenan-induced decrease in immune complexes clearance in mice.
Journal of ethnopharmacology 1996;53(1):1-4.
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1996: Nagai T; Urata M; Yamada H
In vivo anti-influenza virus activity of Kampo (Japanese herbal) medicine "Sho-seiryu-to"--effects on aged mice, against subtypes of a viruses and B virus, and therapeutic effect.
Immunopharmacology and immunotoxicology 1996;18(2):193-208.
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1996: Kiyohara H; Takemoto N; Zhao J F; Kawamura H; Yamada H
Pectic polysaccharides from roots of Glycyrrhiza uralensis: possible contribution of neutral oligosaccharides in the galacturonase-resistant region to anti-complementary and mitogenic activities.
Planta medica 1996;62(1):14-9.
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1995: Kiyohara H; Matsumoto T; Komatsu Y; Yamada H
Protective effect of oral administration of a pectic polysaccharide fraction from a Kampo (Japanese herbal) medicine "Juzen-Taiho-To" on adverse effects of cis-diaminedichloroplatinum.
Planta medica 1995;61(6):531-34.
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1995: Kiyohara H; Matsumoto T; Takemoto N; Kawamura H; Komatsu Y; Yamada H
Effect of oral administration of a pectic polysaccharide fraction from a kampo (Japanese herbal) medicine "juzen-taiho-to" on antibody response of mice.
Planta medica 1995;61(5):429-34.
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1995: Nagai T; Suzuki Y; Yamada H
Comparison of substrate specificities of sialidase activity between purified enzymes from influenza virus A (H1N1 and H3N2 subtypes) and B strains and their original viruses.
Biological & pharmaceutical bulletin 1995;18(9):1251-4.
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1995: Yamada H
[Structure and pharmacological activity of pectic polysaccharides from the roots of Bupleurum falcatum L.]
Nippon yakurigaku zasshi. Folia pharmacologica Japonica 1995;106(3):229-37.
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1995: Matsumoto T; Hirano M; Kiyohara H; Yamada H
Characterisation of the endo-polygalacturonase-resistant region of the pectin from Bupleurum falcatum L.--a polysaccharide with an active function in clearance of immune complexes.
Carbohydrate research 1995;270(2):221-9.
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1995: Nagai T; Suzuki Y; Tomimori T; Yamada H
Antiviral activity of plant flavonoid, 5,7,4'-trihydroxy-8-methoxyflavone, from the roots of Scutellaria baicalensis against influenza A (H3N2) and B viruses.
Biological & pharmaceutical bulletin 1995;18(2):295-9.
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1995: Iijima K; Kiyohara H; Tanaka M; Matsumoto T; Cyong J C; Yamada H
Preventive effect of taraxasteryl acetate from Inula britannica subsp. japonica on experimental hepatitis in vivo.
Planta medica 1995;61(1):50-3.
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1995: Matsumoto T; Yamada H
Regulation of immune complexes binding of macrophages by pectic polysaccharide from Bupleurum falcatum L.: pharmacological evidence for the requirement of intracellular calcium/calmodulin on Fc receptor up-regulation by bupleuran 2IIb.
The Journal of pharmacy and pharmacology 1995;47(2):152-6.
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1995: Nagai T; Moriguchi R; Suzuki Y; Tomimori T; Yamada H
Mode of action of the anti-influenza virus activity of plant flavonoid, 5,7,4'-trihydroxy-8-methoxyflavone, from the roots of Scutellaria baicalensis.
Antiviral research 1995;26(1):11-25.
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1994: Hirano M; Kiyohara H; Yamada H
Existence of a rhamnogalacturonan II-like region in bioactive pectins from medicinal herbs.
Planta medica 1994;60(5):450-4.
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1994: Wang N L; Kiyohara H; Matsumoto T; Otsuka H; Hirano M; Yamada H
Polyclonal antibody against a complement-activating pectin from the roots of Angelica acutiloba.
Planta medica 1994;60(5):425-9.
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1994: Kiyohara H; Hirano M; Wen X G; Matsumoto T; Sun X B; Yamada H
Characterisation of an anti-ulcer pectic polysaccharide from leaves of Panax ginseng C.A. Meyer.
Carbohydrate research 1994;263(1):89-101.
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1994: Nagai T; Yamada H
In vivo anti-influenza virus activity of kampo (Japanese herbal) medicine "sho-seiryu-to" and its mode of action.
International journal of immunopharmacology 1994;16(8):605-13.
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1994: Chen X G; Nagai T; Yamada H
Sialidase in rabbit blood. Characterization of sialidase purified from rabbit erythrocyte membrane.
European journal of biochemistry / FEBS 1994;221(2):655-64.
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1994: Hirano M; Kiyohara H; Matsumoto T; Yamada H
Structural studies of endopolygalacturonase-resistant fragments of an antiulcer pectin from the roots of Bupleurum falcatum L.
Carbohydrate research 1994;251():145-62.
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1994: Zhao Q C; Kiyohara H; Yamada H
Anti-complementary neutral polysaccharides from leaves of Artemisia princeps.
Phytochemistry 1994;35(1):73-7.
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1993: Zhao J F; Kiyohara H; Matsumoto T; Yamada H
Anti-complementary acidic polysaccharides from roots of Lithospermum euchromum.
Phytochemistry 1993;34(3):719-24.
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1993: Matsumoto T; Cyong J C; Kiyohara H; Matsui H; Abe A; Hirano M; Danbara H; Yamada H
The pectic polysaccharide from Bupleurum falcatum L. enhances immune-complexes binding to peritoneal macrophages through Fc receptor expression.
International journal of immunopharmacology 1993;15(6):683-93.
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1993: Matsumoto T; Moriguchi R; Yamada H
Role of polymorphonuclear leucocytes and oxygen-derived free radicals in the formation of gastric lesions induced by HCl/ethanol, and a possible mechanism of protection by anti-ulcer polysaccharide.
The Journal of pharmacy and pharmacology 1993;45(6):535-9.
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1992: Yamada H
Chemical and pharmacological studies on efficacy of Japanese and Chinese herbal medicines.
The Kitasato archives of experimental medicine 1992;65(4):159-80.
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1992: Sun X B; Matsumoto T; Yamada H
Purification of an anti-ulcer polysaccharide from the leaves of Panax ginseng.
Planta medica 1992;58(5):445-8.
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1992: Sun X B; Matsumoto T; Yamada H
Anti-ulcer activity and mode of action of the polysaccharide fraction from the leaves of Panax ginseng.
Planta medica 1992;58(5):432-5.
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1992: Nagai T; Miyaichi Y; Tomimori T; Suzuki Y; Yamada H
In vivo anti-influenza virus activity of plant flavonoids possessing inhibitory activity for influenza virus sialidase.
Antiviral research 1992;19(3):207-17.
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1992: Matsumoto T; Cyong J C; Yamada H
Stimulatory effects of ingenols from Euphorbia kansui on the expression of macrophage Fc receptor.
Planta medica 1992;58(3):255-8.
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1992: Zhao Q C; Kiyohara H; Nagai T; Yamada H
Structure of the complement-activating proteoglycan from the pilose antler of Cervus nippon Temminck.
Carbohydrate research 1992;230(2):361-72.
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1992: Yamada H; Kiyohara H; Takemoto N; Zhao J F; Kawamura H; Komatsu Y; Cyong J C; Aburada M; Hosoya E
Mitogenic and complement activating activities of the herbal components of juzen-taiho-to.
Planta medica 1992;58(2):166-70.
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1992: Ikehara S; Kawamura H; Komatsu Y; Yamada H; Hisha H; Yasumizu R; Ohnishi-Inoue Y; Kiyohara H; Hirano M; Aburada M
Effects of medicinal plants on hemopoietic cells.
Advances in experimental medicine and biology 1992;319():319-30.
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1991: Kiyohara H; Yamada H
Carbohydrate chains for expression of complement activating activity in pectic polysaccharides from the roots of Angelica acutiloba kitagawa.
The Kitasato archives of experimental medicine 1991;64(4):167-77.
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1991: Yamada H; Sun X B; Matsumoto T; Ra K S; Hirano M; Kiyohara H
Purification of anti-ulcer polysaccharides from the roots of Bupleurum falcatum.
Planta medica 1991;57(6):555-9.
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1991: Yamada H; Hirano M; Kiyohara H
Partial structure of an anti-ulcer pectic polysaccharide from the roots of Bupleurum falcatum L.
Carbohydrate research 1991;219():173-92.
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1991: Zhao J F; Kiyohara H; Yamada H; Takemoto N; Kawamura H
Heterogeneity and characterisation of mitogenic and anti-complementary pectic polysaccharides from the roots of Glycyrrhiza uralensis Fisch et D.C.
Carbohydrate research 1991;219():149-72.
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1991: Sun X B; Matsumoto T; Yamada H
Effects of a polysaccharide fraction from the roots of Bupleurum falcatum L. on experimental gastric ulcer models in rats and mice.
The Journal of pharmacy and pharmacology 1991;43(10):699-704.
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1991: Yamada H; Nagai T; Cyong J C; Otsuka Y
Mode of complement activation by acidic heteroglycans from the leaves of Artemisia princeps PAMP.
Chemical & pharmaceutical bulletin 1991;39(8):2077-81.
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1991: Kiyohara H; Takemoto N; Komatsu Y; Kawamura H; Hosoya E; Yamada H
Characterization of mitogenic pectic polysaccharides from kampo (Japanese herbal) medicine "juzen-taiho-to".
Planta medica 1991;57(3):254-9.
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1991: Gao Q P; Kiyohara H; Cyong J C; Yamada H
Chemical properties and anti-complementary activities of heteroglycans from the leaves of Panax ginseng.
Planta medica 1991;57(2):132-6.
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1991: Sun X B; Matsumoto T; Kiyohara H; Hirano M; Yamada H
Cytoprotective activity of pectic polysaccharides from the root of panax ginseng.
Journal of ethnopharmacology 1991;31(1):101-7.
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1990: Yamada H; Kiyohara H; Cyong J C; Takemoto N; Komatsu Y; Kawamura H; Aburada M; Hosoya E
Fractionation and characterization of mitogenic and anti-complementary active fractions from kampo (Japanese Herbal) medicine "juzen-taiho-to".
Planta medica 1990;56(4):386-91.
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1990: Nagai T; Miyaichi Y; Tomimori T; Suzuki Y; Yamada H
Inhibition of influenza virus sialidase and anti-influenza virus activity by plant flavonoids.
Chemical & pharmaceutical bulletin 1990;38(5):1329-32.
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1990: Matsumoto T; Tanaka M; Yamada H; Cyong J C
A new photometric microassay for the quantitation of macrophage Fc receptor function. In vitro enzyme-containing immune complexes clearance (EIC) assay.
Journal of immunological methods 1990;129(2):283-90.
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1990: Yamada H; Komiyama K; Kiyohara H; Cyong J C; Hirakawa Y; Otsuka Y
Structural characterization and antitumor activity of a pectic polysaccharide from the roots of Angelica acutiloba.
Planta medica 1990;56(2):182-6.
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1990: Gao Q P; Kiyohara H; Yamada H
Further structural studies of anti-complementary acidic heteroglycans from the leaves of Panax ginseng C.A. Meyer.
Carbohydrate research 1990;196():111-25.
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1989: Yamada H; Nagai T; Takemoto N; Endoh H; Kiyohara H; Kawamura H; Otsuka Y
Plantagoside, a novel alpha-mannosidase inhibitor isolated from the seeds of Plantago asiatica, suppresses immune response.
Biochemical and biophysical research communications 1989;165(3):1292-8.
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1989: Kiyohara H; Cyong J C; Yamada H
Relationship between structure and activity of the "ramified" region in anti-complementary pectic polysaccharides from Angelica acutiloba Kitagawa.
Carbohydrate research 1989;193():201-14.
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1989: Kiyohara H; Yamada H
Structure of an anti-complementary arabinogalactan from the root of Angelica acutiloba Kitagawa.
Carbohydrate research 1989;193():173-92.
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1989: Kiyohara H; Cyong J C; Yamada H
Relationship between structure and activity of an anti-complementary arabinogalactan from the roots of Angelica acutiloba Kitagawa.
Carbohydrate research 1989;193():193-200.
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1989: Nagai T; Miyaichi Y; Tomimori T; Yamada H
Inhibition of mouse liver sialidase by plant flavonoids.
Biochemical and biophysical research communications 1989;163(1):25-31.
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1989: Yamada H; Ra K S; Kiyohara H; Cyong J C; Otsuka Y
Structural characterization of an anti-complementary pectic polysaccharide from the roots of Bupleurum falcatum L.
Carbohydrate research 1989;189():209-26.
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1988: Kiyohara H; Cyong J C; Yamada H
Structure and anti-complementary activity of pectic polysaccharides isolated from the root of Angelica acutiloba Kitagawa.
Carbohydrate research 1988;182(2):259-75.
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1987: Kiyohara H; Yamada H; Otsuka Y
Unit structure of the anti-complementary arabinogalactan from Angelica acutiloba Kitagawa.
Carbohydrate research 1987;167():221-37.
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1987: Cyong J; Matsumoto T; Arakawa K; Kiyohara H; Yamada H; Otsuka Y
Anti-Bacteroides fragilis substance from rhubarb.
Journal of ethnopharmacology 1987;19(3):279-83.
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