Keith Yamamoto

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So Alex Y -L; Bernal Teresita U; Pillsbury Marlisa L; Yamamoto Keith R; Feldman Brian J
Glucocorticoid regulation of the circadian clock modulates glucose homeostasis.
Meijsing Sebastiaan H; Pufall Miles A; So Alex Y; Bates Darren L; Chen Lin; Yamamoto Keith R
DNA binding site sequence directs glucocorticoid receptor structure and activity.
Jones Jeremy O; Bolton Eric C; Huang Yong; Feau Clementine; Guy R Kiplin; Yamamoto Keith R; Hann Byron; Diamond Marc I
Non-competitive androgen receptor inhibition in vitro and in vivo.

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All Publications

2009: So Alex Y -L; Bernal Teresita U; Pillsbury Marlisa L; Yamamoto Keith R; Feldman Brian J
Glucocorticoid regulation of the circadian clock modulates glucose homeostasis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(41):17582-7.
2009: Meijsing Sebastiaan H; Pufall Miles A; So Alex Y; Bates Darren L; Chen Lin; Yamamoto Keith R
DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science (New York, N.Y.) 2009;324(5925):407-10.
2009: Jones Jeremy O; Bolton Eric C; Huang Yong; Feau Clementine; Guy R Kiplin; Yamamoto Keith R; Hann Byron; Diamond Marc I
Non-competitive androgen receptor inhibition in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(17):7233-8.
2008: Pantoja Carlos; Huff Jason T; Yamamoto Keith R
Glucocorticoid signaling defines a novel commitment state during adipogenesis in vitro.
Molecular biology of the cell 2008;19(10):4032-41.
2008: So Alex Yick-Lun; Cooper Samantha B; Feldman Brian J; Manuchehri Mitra; Yamamoto Keith R
Conservation analysis predicts in vivo occupancy of glucocorticoid receptor-binding sequences at glucocorticoid-induced genes.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(15):5745-9.
2008: Taubert Stefan; Hansen Malene; Van Gilst Marc R; Cooper Samantha B; Yamamoto Keith R
The Mediator subunit MDT-15 confers metabolic adaptation to ingested material.
PLoS genetics 2008;4(2):e1000021.
2007: Woodruff Prescott G; Boushey Homer A; Dolganov Gregory M; Barker Chris S; Yang Yee Hwa; Donnelly Samantha; Ellwanger Almut; Sidhu Sukhvinder S; Dao-Pick Trang P; Pantoja Carlos; Erle David J; Yamamoto Keith R; Fahy John V
Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(40):15858-63.
2007: Bolton Eric C; So Alex Y; Chaivorapol Christina; Haqq Christopher M; Li Hao; Yamamoto Keith R
Cell- and gene-specific regulation of primary target genes by the androgen receptor.
Genes & development 2007;21(16):2005-17.
2007: So Alex Yick-Lun; Chaivorapol Christina; Bolton Eric C; Li Hao; Yamamoto Keith R
Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor.
PLoS genetics 2007;3(6):e94.
2007: Ricketson D; Hostick U; Fang L; Yamamoto K R; Darimont B D
A conformational switch in the ligand-binding domain regulates the dependence of the glucocorticoid receptor on Hsp90.
Journal of molecular biology 2007;368(3):729-41.
2007: Meijsing Sebastiaan H; Elbi Cem; Luecke Hans F; Hager Gordon L; Yamamoto Keith R
The ligand binding domain controls glucocorticoid receptor dynamics independent of ligand release.
Molecular and cellular biology 2007;27(7):2442-51.
2006: Feldman Brian J; Streeper Ryan S; Farese Robert V; Yamamoto Keith R
Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(42):15675-80.
2006: Taubert Stefan; Van Gilst Marc R; Hansen Malene; Yamamoto Keith R
A Mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and -independent pathways in C. elegans.
Genes & development 2006;20(9):1137-49.
2006: Wang Jen-Chywan; Shah Nilesh; Pantoja Carlos; Meijsing Sebastiaan H; Ho Joseph D; Scanlan Thomas S; Yamamoto Keith R
Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity.
Genes & development 2006;20(6):689-99.
2005: Lo Bernard; Zettler Patricia; Cedars Marcelle I; Gates Elena; Kriegstein Arnold R; Oberman Michelle; Reijo Pera Renee; Wagner Richard M; Wuerth Mary T; Wolf Leslie E; Yamamoto Keith R
A new era in the ethics of human embryonic stem cell research.
Stem cells (Dayton, Ohio) 2005;23(10):1454-9.
2005: Van Gilst Marc R; Hadjivassiliou Haralambos; Yamamoto Keith R
A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13496-501.
2005: Luecke Hans F; Yamamoto Keith R
The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression.
Genes & development 2005;19(9):1116-27.
2005: Van Gilst Marc R; Hadjivassiliou Haralambos; Jolly Amber; Yamamoto Keith R
Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans.
PLoS biology 2005;3(2):e53.
2005: Shostak Yuriy; Yamamoto Keith R
Overlapping but separable determinants of DNA binding and nuclear localization map to the C-terminal end of the Caenorhabditis elegans DAF-12 DNA binding domain.
The Journal of biological chemistry 2005;280(8):6554-60.
2004: Wang Jen-Chywan; Derynck Mika Kakefuda; Nonaka Daisuke F; Khodabakhsh Daniel B; Haqq Chris; Yamamoto Keith R
Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(44):15603-8.
2004: Yamamoto Keith R
Bankrolling stem-cell research with California dollars.
The New England journal of medicine 2004;351(17):1711-3.
2004: Shostak Yuriy; Van Gilst Marc R; Antebi Adam; Yamamoto Keith R
Identification of C. elegans DAF-12-binding sites, response elements, and target genes.
Genes & development 2004;18(20):2529-44.
2004: Lo Bernard; Chou Vicki; Cedars Marcelle I; Gates Elena; Taylor Robert N; Wagner Richard M; Wolf Leslie; Yamamoto Keith R
Informed consent in human oocyte, embryo, and embryonic stem cell research.
Fertility and sterility 2004;82(3):559-63.
2004: Wang Jen-Chywan; Walker Amy; Blackwell T Keith; Yamamoto Keith R
The Caenorhabditis elegans ortholog of TRAP240, CeTRAP240/let-19, selectively modulates gene expression and is essential for embryogenesis.
The Journal of biological chemistry 2004;279(28):29270-7.
2004: Freedman Neal D; Yamamoto Keith R
Importin 7 and importin alpha/importin beta are nuclear import receptors for the glucocorticoid receptor.
Molecular biology of the cell 2004;15(5):2276-86.
2004: Kian Tee Meng; Rogatsky Inez; Tzagarakis-Foster Christina; Cvoro Aleksandra; An Jinping; Christy Robert J; Yamamoto Keith R; Leitman Dale C
Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta.
Molecular biology of the cell 2004;15(3):1262-72.
2003: Rogatsky Inez; Wang Jen-Chywan; Derynck Mika K; Nonaka Daisuke F; Khodabakhsh Daniel B; Haqq Christopher M; Darimont Beatrice D; Garabedian Michael J; Yamamoto Keith R
Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):13845-50.
2003: Lo Bernard; Chou Vicki; Cedars Marcelle I; Gates Elena; Taylor Robert N; Wagner Richard M; Wolf Leslie; Yamamoto Keith R
Medicine. Consent from donors for embryo and stem cell research.
Science (New York, N.Y.) 2003;301(5635):921.
2002: Rogatsky Inez; Luecke Hans F; Leitman Dale C; Yamamoto Keith R
Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16701-6.
2002: Freeman Brian C; Yamamoto Keith R
Disassembly of transcriptional regulatory complexes by molecular chaperones.
Science (New York, N.Y.) 2002;296(5576):2232-5.
2001: Rogatsky I; Zarember K A; Yamamoto K R
Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones.
The EMBO journal 2001;20(21):6071-83.
2001: Freeman B C; Yamamoto K R
Continuous recycling: a mechanism for modulatory signal transduction.
Trends in biochemical sciences 2001;26(5):285-90.
2000: Sitcheran R; Emter R; Kralli A; Yamamoto K R
A genetic analysis of glucocorticoid receptor signaling. Identification and characterization of ligand-effect modulators in Saccharomyces cerevisiae.
Genetics 2000;156(3):963-72.
2000: Nissen R M; Yamamoto K R
The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain.
Genes & development 2000;14(18):2314-29.
2000: van Tilborg M A; Lefstin J A; Kruiskamp M; Teuben J; Boelens R; Yamamoto K R; Kaptein R
Mutations in the glucocorticoid receptor DNA-binding domain mimic an allosteric effect of DNA.
Journal of molecular biology 2000;301(4):947-58.
2000: Jamieson C A; Yamamoto K R
Crosstalk pathway for inhibition of glucocorticoid-induced apoptosis by T cell receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7319-24.
2000: Freeman B C; Felts S J; Toft D O; Yamamoto K R
The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies.
Genes & development 2000;14(4):422-34.
2000: Diamond M I; Robinson M R; Yamamoto K R
Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):657-61.
1999: Alberts B M; Ayala F J; Botstein D; Frank E; Holmes E W; Lee R D; Macagno E R; Marrack P; Oparil S; Orkin S H; Rubenstein A H; Slayman C W; Sparling P F; Squire L R; von Hippel P H; Yamamoto K R
Proposed changes for NIH's Center for Scientific Review. Panel on Scientific Boundaries for Review. Center for Scientific Review Advisory Committee, National Institutes of Health.
Science (New York, N.Y.) 1999;285(5428):666-7.
1999: Hong H; Darimont B D; Ma H; Yang L; Yamamoto K R; Stallcup M R
An additional region of coactivator GRIP1 required for interaction with the hormone-binding domains of a subset of nuclear receptors.
The Journal of biological chemistry 1999;274(6):3496-502.
1998: Darimont B D; Wagner R L; Apriletti J W; Stallcup M R; Kushner P J; Baxter J D; Fletterick R J; Yamamoto K R
Structure and specificity of nuclear receptor-coactivator interactions.
Genes & development 1998;12(21):3343-56.
1998: Pearce D; Matsui W; Miner J N; Yamamoto K R
Glucocorticoid receptor transcriptional activity determined by spacing of receptor and nonreceptor DNA sites.
The Journal of biological chemistry 1998;273(46):30081-5.
1998: Lefstin J A; Yamamoto K R
Allosteric effects of DNA on transcriptional regulators.
Nature 1998;392(6679):885-8.
1998: Yamamoto K R; Darimont B D; Wagner R L; Iñiguez-Lluhí J A
Building transcriptional regulatory complexes: signals and surfaces.
Cold Spring Harbor symposia on quantitative biology 1998;63():587-98.
1997: Lichtarge O; Yamamoto K R; Cohen F E
Identification of functional surfaces of the zinc binding domains of intracellular receptors.
Journal of molecular biology 1997;274(3):325-37.
1997: Krstic M D; Rogatsky I; Yamamoto K R; Garabedian M J
Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor.
Molecular and cellular biology 1997;17(7):3947-54.
1997: Iñiguez-Lluhí J A; Lou D Y; Yamamoto K R
Three amino acid substitutions selectively disrupt the activation but not the repression function of the glucocorticoid receptor N terminus.
The Journal of biological chemistry 1997;272(7):4149-56.
1996: Miller M E; Cairns B R; Levinson R S; Yamamoto K R; Engel D A; Smith M M
Adenovirus E1A specifically blocks SWI/SNF-dependent transcriptional activation.
Molecular and cellular biology 1996;16(10):5737-43.
1996: Cairns B R; Levinson R S; Yamamoto K R; Kornberg R D
Essential role of Swp73p in the function of yeast Swi/Snf complex.
Genes & development 1996;10(17):2131-44.
1996: Xu M; Chakraborti P K; Garabedian M J; Yamamoto K R; Simons S S
Modular structure of glucocorticoid receptor domains is not equivalent to functional independence. Stability and activity of the steroid binding domain are controlled by sequences in separate domains.
The Journal of biological chemistry 1996;271(35):21430-8.
1996: Kralli A; Yamamoto K R
An FK506-sensitive transporter selectively decreases intracellular levels and potency of steroid hormones.
The Journal of biological chemistry 1996;271(29):17152-6.
1996: Starr D B; Matsui W; Thomas J R; Yamamoto K R
Intracellular receptors use a common mechanism to interpret signaling information at response elements.
Genes & development 1996;10(10):1271-83.
1995: Holley S J; Yamamoto K R
A role for Hsp90 in retinoid receptor signal transduction.
Molecular biology of the cell 1995;6(12):1833-42.
1995: Bohen S P; Kralli A; Yamamoto K R
Hold 'em and fold 'em: chaperones and signal transduction.
Science (New York, N.Y.) 1995;268(5215):1303-4.
1995: Vivanco M D; Johnson R; Galante P E; Hanahan D; Yamamoto K R
A transition in transcriptional activation by the glucocorticoid and retinoic acid receptors at the tumor stage of dermal fibrosarcoma development.
The EMBO journal 1995;14(10):2217-28.
1995: Kralli A; Bohen S P; Yamamoto K R
LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4701-5.
1995: van Tilborg M A; Bonvin A M; Hård K; Davis A L; Maler B; Boelens R; Yamamoto K R; Kaptein R
Structure refinement of the glucocorticoid receptor-DNA binding domain from NMR data by relaxation matrix calculations.
Journal of molecular biology 1995;247(4):689-700.
1995: Yamamoto K R
Multilayered control of intracellular receptor function.
Harvey lectures 1995;91():1-19.
1994: Lefstin J A; Thomas J R; Yamamoto K R
Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions.
Genes & development 1994;8(23):2842-56.
1994: La Baer J; Yamamoto K R
Analysis of the DNA-binding affinity, sequence specificity and context dependence of the glucocorticoid receptor zinc finger region.
Journal of molecular biology 1994;239(5):664-88.
1993: Bohen S P; Yamamoto K R
Isolation of Hsp90 mutants by screening for decreased steroid receptor function.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11424-8.
1993: Scherrer L C; Picard D; Massa E; Harmon J M; Simons S S; Yamamoto K R; Pratt W B
Evidence that the hormone binding domain of steroid receptors confers hormonal control on chimeric proteins by determining their hormone-regulated binding to heat-shock protein 90.
Biochemistry 1993;32(20):5381-6.
1993: Hara K; Fukuyama K; Sakai H; Yamamoto K; Epstein W L
Purification and immunohistochemical localization of aspartic proteinases in rat epidermis.
The Journal of investigative dermatology 1993;100(4):394-9.
1993: Imai E; Miner J N; Mitchell J A; Yamamoto K R; Granner D K
Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids.
The Journal of biological chemistry 1993;268(8):5353-6.
1993: Pearce D; Yamamoto K R
Mineralocorticoid and glucocorticoid receptor activities distinguished by nonreceptor factors at a composite response element.
Science (New York, N.Y.) 1993;259(5098):1161-5.
1992: Yoshinaga S K; Peterson C L; Herskowitz I; Yamamoto K R
Roles of SWI1, SWI2, and SWI3 proteins for transcriptional enhancement by steroid receptors.
Science (New York, N.Y.) 1992;258(5088):1598-604.
1992: Miner J N; Yamamoto K R
The basic region of AP-1 specifies glucocorticoid receptor activity at a composite response element.
Genes & development 1992;6(12B):2491-501.
1992: Garabedian M J; Yamamoto K R
Genetic dissection of the signaling domain of a mammalian steroid receptor in yeast.
Molecular biology of the cell 1992;3(11):1245-57.
1992: Chakraborti P K; Garabedian M J; Yamamoto K R; Simons S S
Role of cysteines 640, 656, and 661 in steroid binding to rat glucocorticoid receptors.
The Journal of biological chemistry 1992;267(16):11366-73.
1992: Amero S A; Kretsinger R H; Moncrief N D; Yamamoto K R; Pearson W R
The origin of nuclear receptor proteins: a single precursor distinct from other transcription factors.
Molecular endocrinology (Baltimore, Md.) 1992;6(1):3-7.
1991: Remerowski M L; Kellenbach E; Boelens R; van der Marel G A; van Boom J H; Maler B A; Yamamoto K R; Kaptein R
1H NMR studies of DNA recognition by the glucocorticoid receptor: complex of the DNA binding domain with a half-site response element.
Biochemistry 1991;30(50):11620-4.
1991: Chakraborti P K; Garabedian M J; Yamamoto K R; Simons S S
Creation of "super" glucocorticoid receptors by point mutations in the steroid binding domain.
The Journal of biological chemistry 1991;266(33):22075-8.
1991: Miner J N; Yamamoto K R
Regulatory crosstalk at composite response elements.
Trends in biochemical sciences 1991;16(11):423-6.
1991: Kellenbach E; Maler B A; Yamamoto K R; Boelens R; Kaptein R
Identification of the metal coordinating residues in the DNA binding domain of the glucocorticoid receptor by 113Cd-1H heteronuclear NMR spectroscopy.
FEBS letters 1991;291(2):367-70.
1991: Miner J N; Diamond M I; Yamamoto K R
Joints in the regulatory lattice: composite regulation by steroid receptor-AP1 complexes.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1991;2(10):525-30.
1991: Luisi B F; Xu W X; Otwinowski Z; Freedman L P; Yamamoto K R; Sigler P B
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA.
Nature 1991;352(6335):497-505.
1991: Yoshinaga S K; Yamamoto K R
Signaling and regulation by a mammalian glucocorticoid receptor in Drosophila cells.
Molecular endocrinology (Baltimore, Md.) 1991;5(6):844-53.
1991: Kellenbach E; Härd T; Boelens R; Dahlman K; Carlstedt-Duke J; Gustafsson J A; van der Marel G A; van Boom J H; Maler B; Yamamoto K R
Photo-CIDNP study of the interaction between the glucocorticoid receptor DNA-binding domain and glucocorticoid response elements.
Journal of biomolecular NMR 1991;1(1):105-10.
1991: Schena M; Picard D; Yamamoto K R
Vectors for constitutive and inducible gene expression in yeast.
Methods in enzymology 1991;194():389-98.
1990: Privalsky M L; Sharif M; Yamamoto K R
The viral erbA oncogene protein, a constitutive repressor in animal cells, is a hormone-regulated activator in yeast.
Cell 1990;63(6):1277-86.
1990: Picard D; Khursheed B; Garabedian M J; Fortin M G; Lindquist S; Yamamoto K R
Reduced levels of hsp90 compromise steroid receptor action in vivo.
Nature 1990;348(6297):166-8.
1990: Diamond M I; Miner J N; Yoshinaga S K; Yamamoto K R
Transcription factor interactions: selectors of positive or negative regulation from a single DNA element.
Science (New York, N.Y.) 1990;249(4974):1266-72.
1990: Howard K J; Holley S J; Yamamoto K R; Distelhorst C W
Mapping the HSP90 binding region of the glucocorticoid receptor.
The Journal of biological chemistry 1990;265(20):11928-35.
1990: Härd T; Kellenbach E; Boelens R; Maler B A; Dahlman K; Freedman L P; Carlstedt-Duke J; Yamamoto K R; Gustafsson J A; Kaptein R
Solution structure of the glucocorticoid receptor DNA-binding domain.
Science (New York, N.Y.) 1990;249(4965):157-60.
1990: Debs R J; Freedman L P; Edmunds S; Gaensler K L; Düzgünes N; Yamamoto K R
Regulation of gene expression in vivo by liposome-mediated delivery of a purified transcription factor.
The Journal of biological chemistry 1990;265(18):10189-92.
1990: Picard D; Schena M; Yamamoto K R
An inducible expression vector for both fission and budding yeast.
Gene 1990;86(2):257-61.
1990: Picard D; Kumar V; Chambon P; Yamamoto K R
Signal transduction by steroid hormones: nuclear localization is differentially regulated in estrogen and glucocorticoid receptors.
Cell regulation 1990;1(3):291-9.
1989: Schena M; Freedman L P; Yamamoto K R
Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities.
Genes & development 1989;3(10):1590-601.
1989: Eilers M; Picard D; Yamamoto K R; Bishop J M
Chimaeras of myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells.
Nature 1989;340(6228):66-8.
1989: Freedman L P; Yoshinaga S K; Vanderbilt J N; Yamamoto K R
In vitro transcription enhancement by purified derivatives of the glucocorticoid receptor.
Science (New York, N.Y.) 1989;245(4915):298-301.
1988: Sakai D D; Helms S; Carlstedt-Duke J; Gustafsson J A; Rottman F M; Yamamoto K R
Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene.
Genes & development 1988;2(9):1144-54.
1988: Picard D; Salser S J; Yamamoto K R
A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor.
Cell 1988;54(7):1073-80.
1988: Freedman L P; Yamamoto K R; Luisi B F; Sigler P B
More fingers in hand.
Cell 1988;54(4):444.
1988: Schena M; Yamamoto K R
Mammalian glucocorticoid receptor derivatives enhance transcription in yeast.
Science (New York, N.Y.) 1988;241(4868):965-7.
1988: Godowski P J; Picard D; Yamamoto K R
Signal transduction and transcriptional regulation by glucocorticoid receptor-LexA fusion proteins.
Science (New York, N.Y.) 1988;241(4867):812-6.
1988: Freedman L P; Luisi B F; Korszun Z R; Basavappa R; Sigler P B; Yamamoto K R
The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain.
Nature 1988;334(6182):543-6.
1988: Yamamoto K; Chadarevian A; Pellegrini M
Juvenile hormone action mediated in male accessory glands of Drosophila by calcium and kinase C.
Science (New York, N.Y.) 1988;239(4842):916-9.
1988: Yamamoto K R; Godowski P J; Picard D
Ligand-regulated nonspecific inactivation of receptor function: a versatile mechanism for signal transduction.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 2():803-11.
1987: Picard D; Yamamoto K R
Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.
The EMBO journal 1987;6(11):3333-40.
1987: Rusconi S; Yamamoto K R
Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor.
The EMBO journal 1987;6(5):1309-15.
1987: Miesfeld R; Godowski P J; Maler B A; Yamamoto K R
Glucocorticoid receptor mutants that define a small region sufficient for enhancer activation.
Science (New York, N.Y.) 1987;236(4800):423-7.
1987: Parslow T G; Jones S D; Bond B; Yamamoto K R
The immunoglobulin octanucleotide: independent activity and selective interaction with enhancers.
Science (New York, N.Y.) 1987;235(4795):1498-501.
1987: Godowski P J; Rusconi S; Miesfeld R; Yamamoto K R
Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement.
Nature 1987;325(6102):365-8.
1987: Vanderbilt J N; Miesfeld R; Maler B A; Yamamoto K R
Intracellular receptor concentration limits glucocorticoid-dependent enhancer activity.
Molecular endocrinology (Baltimore, Md.) 1987;1(1):68-74.
1986: Firestone G L; John N J; Yamamoto K R
Glucocorticoid-regulated glycoprotein maturation in wild-type and mutant rat cell lines.
The Journal of cell biology 1986;103(6 Pt 1):2323-31.
1986: Miesfeld R; Rusconi S; Godowski P J; Maler B A; Okret S; Wikström A C; Gustafsson J A; Yamamoto K R
Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA.
Cell 1986;46(3):389-99.
1986: DeFranco D; Yamamoto K R
Two different factors act separately or together to specify functionally distinct activities at a single transcriptional enhancer.
Molecular and cellular biology 1986;6(4):993-1001.
1985: Jones K A; Yamamoto K R; Tjian R
Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro.
Cell 1985;42(2):559-72.
1985: Yamamoto K R
Steroid receptor regulated transcription of specific genes and gene networks.
Annual review of genetics 1985;19():209-52.
1984: Miesfeld R; Okret S; Wikström A C; Wrange O; Gustafsson J A; Yamamoto K R
Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells.
Nature 1984;312(5996):779-81.
1984: Zaret K S; Yamamoto K R
Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element.
Cell 1984;38(1):29-38.
1984: Ucker D S; Yamamoto K R
Early events in the stimulation of mammary tumor virus RNA synthesis by glucocorticoids. Novel assays of transcription rates.
The Journal of biological chemistry 1984;259(12):7416-20.
1984: Gustafsson J A; Carlstedt-Duke J; Okret S; Wikström A C; Wrange O; Payvar F; Yamamoto K
Structure and specific DNA binding of the rat liver glucocorticoid receptor.
Journal of steroid biochemistry 1984;20(1):1-4.
1983: Payvar F; DeFranco D; Firestone G L; Edgar B; Wrange O; Okret S; Gustafsson J A; Yamamoto K R
Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region.
Cell 1983;35(2 Pt 1):381-92.
1983: Chandler V L; Maler B A; Yamamoto K R
DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo.
Cell 1983;33(2):489-99.
1983: Ucker D S; Firestone G L; Yamamoto K R
Glucocorticoids and chromosomal position modulate murine mammary tumor virus transcription by affecting efficiency of promoter utilization.
Molecular and cellular biology 1983;3(4):551-61.
1983: Firestone G L; Yamamoto K R
Two classes of mutant mammary tumor virus-infected HTC cell with defects in glucocorticoid-regulated gene expression.
Molecular and cellular biology 1983;3(2):149-60.
1983: Baumann H; Firestone G L; Burgess T L; Gross K W; Yamamoto K R; Held W A
Dexamethasone regulation of alpha 1-acid glycoprotein and other acute phase reactants in rat liver and hepatoma cells.
The Journal of biological chemistry 1983;258(1):563-70.
1983: Yamamoto K R; Payvar F; Firestone G L; Maler B A; Wrange O; Carlstedt-Duke J; Gustafsson J A; Chandler V L
Biological activity of cloned mammary tumor virus DNA fragments that bind purified glucocorticoid receptor protein in vitro.
Cold Spring Harbor symposia on quantitative biology 1983;47 Pt 2():977-84.
1982: Firestone G L; Payvar F; Yamamoto K R
Glucocorticoid regulation of protein processing and compartmentalization.
Nature 1982;300(5889):221-5.
1982: Feinstein S C; Ross S R; Yamamoto K R
Chromosomal position effects determine transcriptional potential of integrated mammary tumor virus DNA.
Journal of molecular biology 1982;156(3):549-65.
1982: Payvar F; Firestone G L; Ross S R; Chandler V L; Wrange O; Carlstedt-Duke J; Gustafsson J A; Yamamoto K R
Multiple specific binding sites for purified glucocorticoid receptors on mammary tumor virus DNA.
Journal of cellular biochemistry 1982;19(3):241-7.
1981: Ucker D S; Ross S R; Yamamoto K R
Mammary tumor virus DNA contains sequences required for its hormone-regulated transcription.
Cell 1981;27(2 Pt 1):257-66.
1981: Payvar F; Wrange O; Carlstedt-Duke J; Okret S; Gustafsson J A; Yamamoto K R
Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(11):6628-32.
1981: Yamamoto K R; Chandler V L; Ross S R; Ucker D S; Ring J C; Feinstein S C
Integration and activity of mammary tumor virus genes: regulation by hormone receptors and chromosomal position.
Cold Spring Harbor symposia on quantitative biology 1981;45 Pt 2():687-97.

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