Robert Bridges

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Coote K; Atherton-Watson H C; Sugar R; Young A; MacKenzie-Beevor A; Gosling M; Bhalay G; Bloomfield G; Dunstan A; Bridges R J; Sabater J R; Abraham W M; Tully D; Pacoma R; Schumacher A; Harris J; Danahay H
Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease.
Adebamiro Adedotun; Cheng Yi; Rao U Subrahmanyeswara; Danahay Henry; Bridges Robert J
A segment of gamma ENaC mediates elastase activation of Na+ transport.
Moser A James; Gangopadhyay A; Bradbury N A; Peters K W; Frizzell R A; Bridges R J
Electrogenic bicarbonate secretion by prairie dog gallbladder.

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All Publications

2009: Coote K; Atherton-Watson H C; Sugar R; Young A; MacKenzie-Beevor A; Gosling M; Bhalay G; Bloomfield G; Dunstan A; Bridges R J; Sabater J R; Abraham W M; Tully D; Pacoma R; Schumacher A; Harris J; Danahay H
Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease.
The Journal of pharmacology and experimental therapeutics 2009;329(2):764-74.
2007: Adebamiro Adedotun; Cheng Yi; Rao U Subrahmanyeswara; Danahay Henry; Bridges Robert J
A segment of gamma ENaC mediates elastase activation of Na+ transport.
The Journal of general physiology 2007;130(6):611-29.
2007: Moser A James; Gangopadhyay A; Bradbury N A; Peters K W; Frizzell R A; Bridges R J
Electrogenic bicarbonate secretion by prairie dog gallbladder.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(6):G1683-94.
2006: Bertrand C A; Laboisse C; Hopfer U; Bridges R J; Frizzell R A
Methods for detecting internalized, FM 1-43 stained particles in epithelial cells and monolayers.
Biophysical journal 2006;91(10):3872-83.
2006: Kreindler James L; Peters Kathryn W; Frizzell Raymond A; Bridges Robert J
Identification and membrane localization of electrogenic sodium bicarbonate cotransporters in Calu-3 cells.
Biochimica et biophysica acta 2006;1762(7):704-10.
2006: Danahay Henry; Atherton Hazel C; Jackson Alan D; Kreindler James L; Poll Christopher T; Bridges Robert J
Membrane capacitance and conductance changes parallel mucin secretion in the human airway epithelium.
American journal of physiology. Lung cellular and molecular physiology 2006;290(3):L558-69.
2005: Adebamiro Adedotun; Cheng Yi; Johnson John P; Bridges Robert J
Endogenous protease activation of ENaC: effect of serine protease inhibition on ENaC single channel properties.
The Journal of general physiology 2005;126(4):339-52.
2005: Kreindler James L; Jackson Alan D; Kemp Philip A; Bridges Robert J; Danahay Henry
Inhibition of chloride secretion in human bronchial epithelial cells by cigarette smoke extract.
American journal of physiology. Lung cellular and molecular physiology 2005;288(5):L894-902.
2004: Singh Ashvani K; Schultz Bruce D; van Driessche Willy; Bridges Robert J
Transepithelial fluctuation analysis of chloride secretion.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2004;3 Suppl 2():127-32.
2004: Bertrand C A; Danahay H; Poll C T; Laboisse C; Hopfer U; Bridges R J
Niflumic acid inhibits ATP-stimulated exocytosis in a mucin-secreting epithelial cell line.
American journal of physiology. Cell physiology 2004;286(2):C247-55.
2003: Silvis Mark R; Picciano John A; Bertrand Carol; Weixel Kelly; Bridges Robert J; Bradbury Neil A
A mutation in the cystic fibrosis transmembrane conductance regulator generates a novel internalization sequence and enhances endocytic rates.
The Journal of biological chemistry 2003;278(13):11554-60.
2003: Hug Martin J; Tamada Tsutomu; Bridges Robert J
CFTR and bicarbonate secretion by [correction of to] epithelial cells.
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 2003;18():38-42.
2002: Danahay Henry; Atherton Hazel; Jones Gareth; Bridges Robert J; Poll Christopher T
Interleukin-13 induces a hypersecretory ion transport phenotype in human bronchial epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2002;282(2):L226-36.
2002: Singh Ashvani K; Singh Sangeeta; Devor Daniel C; Frizzell Raymond A; van Driessche Willy; Bridges Robert J
Transepithelial impedance analysis of chloride secretion.
Methods in molecular medicine 2002;70():129-42.
2002: Bridges Robert J
Transepithelial measurements of bicarbonate secretion in Calu-3 cells.
Methods in molecular medicine 2002;70():111-28.
2001: Hug M J; Bridges R J
pH regulation and bicarbonate transport of isolated porcine submucosal glands.
JOP : Journal of the pancreas 2001;2(4 Suppl):274-9.
2001: Tamada T; Hug M J; Frizzell R A; Bridges R J
Microelectrode and impedance analysis of anion secretion in Calu-3 cells.
JOP : Journal of the pancreas 2001;2(4 Suppl):219-28.
2001: Bridges R J; Newton B B; Pilewski J M; Devor D C; Poll C T; Hall R L
Na+ transport in normal and CF human bronchial epithelial cells is inhibited by BAY 39-9437.
American journal of physiology. Lung cellular and molecular physiology 2001;281(1):L16-23.
2001: Danahay H; Withey L; Poll C T; van de Graaf S F; Bridges R J
Protease-activated receptor-2-mediated inhibition of ion transport in human bronchial epithelial cells.
American journal of physiology. Cell physiology 2001;280(6):C1455-64.
2001: Singh S; Syme C A; Singh A K; Devor D C; Bridges R J
Benzimidazolone activators of chloride secretion: potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease.
The Journal of pharmacology and experimental therapeutics 2001;296(2):600-11.
2000: Singh A K; Schultz B D; Katzenellenbogen J A; Price E M; Bridges R J; Bradbury N A
Estrogen inhibition of cystic fibrosis transmembrane conductance regulator-mediated chloride secretion.
The Journal of pharmacology and experimental therapeutics 2000;295(1):195-204.
2000: Devor D C; Bridges R J; Pilewski J M
Pharmacological modulation of ion transport across wild-type and DeltaF508 CFTR-expressing human bronchial epithelia.
American journal of physiology. Cell physiology 2000;279(2):C461-79.
2000: Singh A K; Devor D C; Gerlach A C; Gondor M; Pilewski J M; Bridges R J
Stimulation of Cl(-) secretion by chlorzoxazone.
The Journal of pharmacology and experimental therapeutics 2000;292(2):778-87.
1999: Devor D C; Singh A K; Lambert L C; DeLuca A; Frizzell R A; Bridges R J
Bicarbonate and chloride secretion in Calu-3 human airway epithelial cells.
The Journal of general physiology 1999;113(5):743-60.
1999: Bradbury N A; Clark J A; Watkins S C; Widnell C C; Smith H S; Bridges R J
Characterization of the internalization pathways for the cystic fibrosis transmembrane conductance regulator.
The American journal of physiology 1999;276(4 Pt 1):L659-68.
1999: Schultz B D; Singh A K; Devor D C; Bridges R J
Pharmacology of CFTR chloride channel activity.
Physiological reviews 1999;79(1 Suppl):S109-44.
1998: Singh A K; Taskén K; Walker W; Frizzell R A; Watkins S C; Bridges R J; Bradbury N A
Characterization of PKA isoforms and kinase-dependent activation of chloride secretion in T84 cells.
The American journal of physiology 1998;275(2 Pt 1):C562-70.
1998: Lambert L C; Trummell H Q; Singh A; Cassell G H; Bridges R J
Mycoplasma pulmonis inhibits electrogenic ion transport across murine tracheal epithelial cell monolayers.
Infection and immunity 1998;66(1):272-9.
1997: Devor D C; Singh A K; Gerlach A C; Frizzell R A; Bridges R J
Inhibition of intestinal Cl- secretion by clotrimazole: direct effect on basolateral membrane K+ channels.
The American journal of physiology 1997;273(2 Pt 1):C531-40.
1997: Devor D C; Singh A K; Bridges R J; Frizzell R A
Psoralens: novel modulators of Cl- secretion.
The American journal of physiology 1997;272(3 Pt 1):C976-88.
1996: Devor D C; Singh A K; Bridges R J; Frizzell R A
Modulation of Cl- secretion by benzimidazolones. II. Coordinate regulation of apical GCl and basolateral GK.
The American journal of physiology 1996;271(5 Pt 1):L785-95.
1996: Devor D C; Singh A K; Frizzell R A; Bridges R J
Modulation of Cl- secretion by benzimidazolones. I. Direct activation of a Ca(2+)-dependent K+ channel.
The American journal of physiology 1996;271(5 Pt 1):L775-84.
1996: Schultz B D; DeRoos A D; Venglarik C J; Singh A K; Frizzell R A; Bridges R J
Glibenclamide blockade of CFTR chloride channels.
The American journal of physiology 1996;271(2 Pt 1):L192-200.
1996: Venglarik C J; Schultz B D; DeRoos A D; Singh A K; Bridges R J
Tolbutamide causes open channel blockade of cystic fibrosis transmembrane conductance regulator Cl- channels.
Biophysical journal 1996;70(6):2696-703.
1995: Singh A K; Venglarik C J; Bridges R J
Development of chloride channel modulators.
Kidney international 1995;48(4):985-93.
1995: Schultz B D; Venglarik C J; Bridges R J; Frizzell R A
Regulation of CFTR Cl- channel gating by ADP and ATP analogues.
The Journal of general physiology 1995;105(3):329-61.
1994: Venglarik C J; Singh A K; Bridges R J
Comparison of -nitro versus -amino 4,4'-substituents of disulfonic stilbenes as chloride channel blockers.
Molecular and cellular biochemistry 1994;140(2):137-46.
1994: Venglarik C J; Schultz B D; Frizzell R A; Bridges R J
ATP alters current fluctuations of cystic fibrosis transmembrane conductance regulator: evidence for a three-state activation mechanism.
The Journal of general physiology 1994;104(1):123-46.
1994: Bradbury N A; Bridges R J
Role of membrane trafficking in plasma membrane solute transport.
The American journal of physiology 1994;267(1 Pt 1):C1-24.
1994: Fuller C M; Bridges R J; Benos D J
Forskolin- but not ionomycin-evoked Cl- secretion in colonic epithelia depends on intact microtubules.
The American journal of physiology 1994;266(3 Pt 1):C661-8.
1994: Bradbury N A; Cohn J A; Venglarik C J; Bridges R J
Biochemical and biophysical identification of cystic fibrosis transmembrane conductance regulator chloride channels as components of endocytic clathrin-coated vesicles.
The Journal of biological chemistry 1994;269(11):8296-302.
1993: Venglarik C J; Singh A K; Wang R; Bridges R J
Trinitrophenyl-ATP blocks colonic Cl- channels in planar phospholipid bilayers. Evidence for two nucleotide binding sites.
The Journal of general physiology 1993;101(4):545-69.
1992: Bradbury N A; Bridges R J
Regulated membrane vesicle trafficking: a defect in cystic fibrosis corrected by gene transfer.
Biochemical Society transactions 1992;20(2):124S.
1992: Bradbury N A; Bridges R J
Endocytosis is regulated by protein kinase A, but not protein kinase C in a secretory epithelial cell line.
Biochemical and biophysical research communications 1992;184(3):1173-80.
1992: Bradbury N A; Jilling T; Berta G; Sorscher E J; Bridges R J; Kirk K L
Regulation of plasma membrane recycling by CFTR.
Science (New York, N.Y.) 1992;256(5056):530-2.
1992: Bradbury N A; Jilling T; Kirk K L; Bridges R J
Regulated endocytosis in a chloride secretory epithelial cell line.
The American journal of physiology 1992;262(3 Pt 1):C752-9.
1992: Sorscher E J; Fuller C M; Bridges R J; Tousson A; Marchase R B; Brinkley B R; Frizzell R A; Benos D J
Identification of a membrane protein from T84 cells using antibodies made against a DIDS-binding peptide.
The American journal of physiology 1992;262(1 Pt 1):C136-47.
1991: Singh A K; Afink G B; Venglarik C J; Wang R P; Bridges R J
Colonic Cl channel blockade by three classes of compounds.
The American journal of physiology 1991;261(1 Pt 1):C51-63.
1990: Venglarik C J; Bridges R J; Frizzell R A
A simple assay for agonist-regulated Cl and K conductances in salt-secreting epithelial cells.
The American journal of physiology 1990;259(2 Pt 1):C358-64.
1989: Bridges R J; Worrell R T; Frizzell R A; Benos D J
Stilbene disulfonate blockade of colonic secretory Cl- channels in planar lipid bilayers.
The American journal of physiology 1989;256(4 Pt 1):C902-12.
1989: Bridges R J; Cragoe E J; Frizzell R A; Benos D J
Inhibition of colonic Na+ transport by amiloride analogues.
The American journal of physiology 1989;256(1 Pt 1):C67-74.

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Robert Bridges

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