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Masayuki Yamamoto

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Kosuke Okada; Naohiro Gotoh; Etsuko Hashimoto; Masaki Horie; Tetsuro Ishii; Hirokazu Sugimoto; Hiroshi Takahashi; Katsutoshi Tokushige; Hirotoshi Utsunomiya; Eiji Warabi; Masayuki Yamamoto; Junichi Shoda
Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet.
Akira Ohkoshi; Masao Ono; Takafumi Suzuki; Toshimitsu Kobayashi; Masayuki Yamamoto
Roles of Keap1-Nrf2 system in upper aerodigestive tract carcinogenesis.
Ahmed Y Shanab; Keiko Taguchi; Jiro Takano; Yuji Tanaka; Ryo Watanabe; Toshiaki Abe; Noriko Himori; Naoko Minegishi; Toshio Miyata; Toru Nakazawa; Morin Ryu; Takaomi Saido; Masayuki Yasuda; Masayuki Yamamoto
Metabolic stress response implicated in diabetic retinopathy: the role of calpain, and the therapeutic impact of calpain inhibitor.

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All Publications

2013: Kosuke Okada; Naohiro Gotoh; Etsuko Hashimoto; Masaki Horie; Tetsuro Ishii; Hirokazu Sugimoto; Hiroshi Takahashi; Katsutoshi Tokushige; Hirotoshi Utsunomiya; Eiji Warabi; Masayuki Yamamoto; Junichi Shoda
Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet.
Journal of gastroenterology 2013;48(5):620-32.
2013: Akira Ohkoshi; Masao Ono; Takafumi Suzuki; Toshimitsu Kobayashi; Masayuki Yamamoto
Roles of Keap1-Nrf2 system in upper aerodigestive tract carcinogenesis.
Cancer prevention research (Philadelphia, Pa.) 2013;6(2):149-59.
2012: Ahmed Y Shanab; Keiko Taguchi; Jiro Takano; Yuji Tanaka; Ryo Watanabe; Toshiaki Abe; Noriko Himori; Naoko Minegishi; Toshio Miyata; Toru Nakazawa; Morin Ryu; Takaomi Saido; Masayuki Yasuda; Masayuki Yamamoto
Metabolic stress response implicated in diabetic retinopathy: the role of calpain, and the therapeutic impact of calpain inhibitor.
Neurobiology of disease 2012;48(3):556-67.
2012: Ritsuko Shimizu; Masayuki Yamamoto
Contribution of GATA1 dysfunction to multi-step leukemogenesis.
Cancer science 2012;103(12):2039-44.
2012: T Yamadori; Masayuki Yamamoto; S Homma; Y Ishii; Ken Itoh; K Kurishima; Y Minami; Y Morishima; M Noguchi; N Hizawa
Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers.
Oncogene 2012;31(45):4768-77.
2012: Yosuke Hirotsu; Fumiki Katsuoka; Takeshi Nagashima; Keiko Nakayama; Yuichiro Nishida; Ryo Funayama; James Douglas Engel; Masayuki Yamamoto
Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks.
Nucleic acids research 2012;40(20):10228-39.
2012: Katsuki Mukaigasa; Hitomi Nakajima; Linh T P Nguyen; Masayuki Yamamoto; Li Li; Makoto Kobayashi
Genetic evidence of an evolutionarily conserved role for Nrf2 in the protection against oxidative stress.
Molecular and cellular biology 2012;32(21):4455-61.
2012: Virpi Lämsä; Anna-Liisa Levonen; Raija Sormunen; Masayuki Yamamoto; Jukka Hakkola
Heme and heme biosynthesis intermediates induce heme oxygenase-1 and cytochrome P450 2A5, enzymes with putative sequential roles in heme and bilirubin metabolism: different requirement for transcription factor nuclear factor erythroid- derived 2-like 2.
Toxicological sciences : an official journal of the Society of Toxicology 2012;130(1):132-44.
2012: Keiko Taguchi; Michiaki Unno; Takaaki Akaike; Nanako Fujikawa; Tetsuro Ishii; Masaaki Komatsu; Hozumi Motohashi; Masayuki Yamamoto
Keap1 degradation by autophagy for the maintenance of redox homeostasis.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(34):13561-6.
2012: Kai Takaya; Thomas W Kensler; Hozumi Motohashi; Ko Onodera; Susumu Satomi; Takafumi Suzuki; Masayuki Yamamoto
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system.
Free radical biology & medicine 2012;53(4):817-27.
2012: Kosuke Okada; Nobuhiko Harada; Etsuko Hashimoto; Masaki Horie; Tetsuro Ishii; Ken Itoh; Hirokazu Sugimoto; Keiko Taguchi; Katsutoshi Tokushige; Tetsuya Ueda; Hirotoshi Utsunomiya; Eiji Warabi; Masayuki Yamamoto; Junichi Shoda
Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis.
Journal of gastroenterology 2012;47(8):924-35.
2012: Yoichiro Mitsuishi; Hiroyuki Aburatani; Yukie Kawatani; Toshihiro Nukiwa; Tatsuhiro Shibata; Keiko Taguchi; Masayuki Yamamoto; Hozumi Motohashi
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Cancer cell 2012;22(1):66-79.
2012: Daisuke Inoue; Hiroshi Kubo; Yasuhiro Miki; Yoichiro Mitsuishi; Hozumi Motohashi; Takayuki Nakagawa; Akira Sakurada; Hironobu Sasano; Kennichi Satoh; Shunichi Sugawara; Satoshi Suzuki; Takashi Suzuki; Nobuyuki Tanaka; Akira Uruno; Mika Watanabe; Chiaki Endo; Masayuki Yamamoto
Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma.
Cancer science 2012;103(4):760-6.
2012: Yoichiro Mitsuishi; Hozumi Motohashi; Masayuki Yamamoto
The Keap1-Nrf2 system in cancers: stress response and anabolic metabolism.
Frontiers in oncology 2012;2():200.
2012: Kit I Tong; Masayuki Yamamoto; Toshiyuki Tanaka
Selective isotope labeling of recombinant proteins in Escherichia coli.
Methods in molecular biology (Clifton, N.J.) 2012;896():439-48.
2011: Tomofumi Hoshino; Tetsuro Ishii; Masahiro Nakayama; Bungo Nishimura; Ritsuku Shimizu; Keiji Tabuchi; Shuho Tanaka; Eiji Warabi; Masayuki Yamamoto; Toru Yanagawa; Akira Hara
Protective role of Nrf2 in age-related hearing loss and gentamicin ototoxicity.
Biochemical and biophysical research communications 2011;415(1):94-8.
2011: Norio Suzuki; Miho Watanabe; Kou-ichi Jishage; Naoko Minegishi; Naoshi Obara; Xiaoqing Pan; Masayuki Yamamoto
Specific contribution of the erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stages.
Molecular and cellular biology 2011;31(18):3896-905.
2011: Kentaro Nakano; Masako Osumi; Mika Toya; Yukiko Asami; Naomi Kamasawa; Akira Yamashita; Aki Yoneda; Masayuki Yamamoto
Pob1 ensures cylindrical cell shape by coupling two distinct rho signaling events during secretory vesicle targeting.
Traffic (Copenhagen, Denmark) 2011;12(6):726-39.
2011: Miki Watanabe-Matsui; Akihiko Muto; Toshitaka Matsui; Ari Itoh-Nakadai; Osamu Nakajima; Kazutaka Murayama; Masayuki Yamamoto; Masao Ikeda-Saito; Kazuhiko Igarashi
Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2.
Blood 2011;117(20):5438-48.
2011: Yuichi Yageta; Yukio Ishii; Yuko Morishima; Hironori Masuko; Satoshi Ano; Tadahiro Yamadori; Ken Itoh; Kaoru Takeuchi; Masayuki Yamamoto; Nobuyuki Hizawa
Role of Nrf2 in host defense against influenza virus in cigarette smoke-exposed mice.
Journal of virology 2011;85(10):4679-90.
2011: Takashi Miura; Yasuhiro Shinkai; Hai-Yan Jiang; Noriko Iwamoto; Daigo Sumi; Keiko Taguchi; Masayuki Yamamoto; Hideto Jinno; Toshiko Tanaka-Kagawa; Arthur K Cho; Yoshito Kumagai
Initial response and cellular protection through the Keap1/Nrf2 system during the exposure of primary mouse hepatocytes to 1,2-naphthoquinone.
Chemical research in toxicology 2011;24(4):559-67.
2011: Yosuke Hirotsu; Fumiki Katsuoka; Ken Itoh; Masayuki Yamamoto
Nrf2 degron-fused reporter system: a new tool for specific evaluation of Nrf2 inducers.
Genes to cells : devoted to molecular & cellular mechanisms 2011;16(4):406-15.
2011: Tomokazu Souma; Michiaki Abe; Takashi Moriguchi; Jun Takai; Noriko Yanagisawa-Miyazawa; Eisuke Shibata; Yasutoshi Akiyama; Takafumi Toyohara; Takehiro Suzuki; Masayuki Tanemoto; Takaaki Abe; Hiroshi Sato; Masayuki Yamamoto; Sadayoshi Ito
Luminal alkalinization attenuates proteinuria-induced oxidative damage in proximal tubular cells.
Journal of the American Society of Nephrology : JASN 2011;22(4):635-48.
2011: Daisuke Inoue; Hiroshi Kubo; Keiko Taguchi; Takashi Suzuki; Masaaki Komatsu; Hozumi Motohashi; Masayuki Yamamoto
Inducible disruption of autophagy in the lung causes airway hyper-responsiveness.
Biochemical and biophysical research communications 2011;405(1):13-8.
2011: Mikiko Suzuki; Ritsuko Shimizu; Masayuki Yamamoto
Transcriptional regulation by GATA1 and GATA2 during erythropoiesis.
International journal of hematology 2011;93(2):150-5.
2011: Keiko Taguchi; Hozumi Motohashi; Masayuki Yamamoto
Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution.
Genes to cells : devoted to molecular & cellular mechanisms 2011;16(2):123-40.
2011: Yukie Kawatani; Takafumi Suzuki; Ritsuko Shimizu; Vincent P Kelly; Masayuki Yamamoto
Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia.
Blood 2011;117(3):986-96.
2011: Hitomi Nakajima; Yaeko Nakajima-Takagi; Yutaka Tamaru; Tadayuki Tsujita; Takeshi Wakasa; Masayuki Yamamoto; Shin-Ichi Akiyama; Hiroshi Kaneko; Katsuki Mukaigasa; Makoto Kobayashi
Tissue-restricted expression of Nrf2 and its target genes in zebrafish with gene-specific variations in the induction profiles.
PloS one 2011;6(10):e26884.
2011: Xiaoqing Pan; Norio Suzuki; Ikuo Hirano; Naoko Minegishi; Shun Yamazaki; Masayuki Yamamoto
Isolation and characterization of renal erythropoietin-producing cells from genetically produced anemia mice.
PloS one 2011;6(10):e25839.
2011: Tadayuki Tsujita; Li Li; Hitomi Nakajima; Noriko Iwamoto; Yaeko Nakajima-Takagi; Ken Ohashi; Koichi Kawakami; Yoshito Kumagai; Bruce A Freeman; Masayuki Yamamoto; Makoto Kobayashi
Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish.
Genes to cells : devoted to molecular & cellular mechanisms 2011;16(1):46-57.
2011: Hozumi Motohashi; Rie Fujita; Mariko Takayama; Ai Inoue; Fumiki Katsuoka; Emery H Bresnick; Masayuki Yamamoto
Molecular determinants for small Maf protein control of platelet production.
Molecular and cellular biology 2011;31(1):151-62.
2010: Michelle Kerns; Daryle Joseph Depianto; Masayuki Yamamoto; Pierre A Coulombe
Differential modulation of keratin expression by sulforaphane occurs via Nrf2-dependent and -independent pathways in skin epithelia.
Molecular biology of the cell 2010;21(23):4068-75.
2010: Zahoor Ahmad Shah; Rung-chi Li; Abdullah Shafique Ahmad; Thomas W Kensler; Masayuki Yamamoto; Shyam Biswal; Sylvain Dore
The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(12):1951-61.
2010: Mariko Takayama; Rie Fujita; Mikiko Suzuki; Ryuhei Okuyama; Setsuya Aiba; Hozumi Motohashi; Masayuki Yamamoto
Genetic analysis of hierarchical regulation for Gata1 and NF-E2 p45 gene expression in megakaryopoiesis.
Molecular and cellular biology 2010;30(11):2668-80.
2010: Virpi Lämsä; Anna-Liisa Levonen; Hanna Leinonen; Seppo Ylä-Herttuala; Masayuki Yamamoto; Jukka Hakkola
Cytochrome P450 2A5 constitutive expression and induction by heavy metals is dependent on redox-sensitive transcription factor Nrf2 in liver.
Chemical research in toxicology 2010;23(5):977-85.
2010: Hiroshi Kaneko; Ritsuko Shimizu; Masayuki Yamamoto
GATA factor switching during erythroid differentiation.
Current opinion in hematology 2010;17(3):163-8.
2010: Koichi Uno; Tarl Prow; Imran A Bhutto; Adi N Yerrapureddy; D Scott McLeod; Masayuki Yamamoto; SEKHAR POTHIREDDY; Gerard A Lutty
Role of Nrf2 in retinal vascular development and the vaso-obliterative phase of oxygen-induced retinopathy.
Experimental eye research 2010;90(4):493-500.
2010: Katsuyuki Iida; Junsei Mimura; Ken Itoh; Chikara Ohyama; Yoshiaki Fujii-Kuriyama; Toru Shimazui; Hideyuki Akaza; Masayuki Yamamoto
Suppression of AhR signaling pathway is associated with the down-regulation of UDP-glucuronosyltransferases during BBN-induced urinary bladder carcinogenesis in mice.
Journal of biochemistry 2010;147(3):353-60.
2010: Kibom Kim; Norio Suzuki; Kinuko Ohneda; Naoko Minegishi; Masayuki Yamamoto
Fractionation of mature eosinophils in GATA-reporter transgenic mice.
The Tohoku journal of experimental medicine 2010;220(2):127-38.
2010: Miki Takeuchi; Hiroshi Kaneko; Keizo Nishikawa; Koichi Kawakami; Masayuki Yamamoto; Makoto Kobayashi
Efficient transient rescue of hematopoietic mutant phenotypes in zebrafish using Tol2-mediated transgenesis.
Development, growth & differentiation 2010;52(2):245-50.
2010: Hirokazu Sugimoto; Kosuke Okada; Junichi Shoda; Eiji Warabi; Kazunori Ishige; Tetsuya Ueda; Keiko Taguchi; Toru Yanagawa; Akira Nakahara; Ichinosuke Hyodo; Tetsuro Ishii; Masayuki Yamamoto
Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice.
American journal of physiology. Gastrointestinal and liver physiology 2010;298(2):G283-94.
2010: Hozumi Motohashi; Momoko Kimura; Rie Fujita; Ai Inoue; Xiaoqing Pan; Mariko Takayama; Fumiki Katsuoka; Hiroyuki Aburatani; Emery H Bresnick; Masayuki Yamamoto
NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation.
Blood 2010;115(3):677-86.
2010: Nobunao Wakabayashi; Soona Shin; Stephen L Slocum; Elin S Agoston; Junko Wakabayashi; Mi-Kyoung Kwak; Vikas Misra; Shyam Biswal; Masayuki Yamamoto; Thomas W Kensler
Regulation of notch1 signaling by nrf2: implications for tissue regeneration.
Science signaling 2010;3(130):ra52.
2010: Norihiro Kikuchi; Yukio Ishii; Yuko Morishima; Yuichi Yageta; Norihiro Haraguchi; Ken Itoh; Masayuki Yamamoto; Nobuyuki Hizawa
Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance.
Respiratory research 2010;11():31.
2010: Eri Kobayashi; Ritsuko Shimizu; Yuko Kikuchi; Satoru Takahashi; Masayuki Yamamoto
Loss of the Gata1 gene IE exon leads to variant transcript expression and the production of a GATA1 protein lacking the N-terminal domain.
The Journal of biological chemistry 2010;285(1):773-83.
2009: Kosuke Okada; Junichi Shoda; Keiko Taguchi; Jonathan M Maher; Kaoru Ishizaki; Yoshimi Inoue; Makio Ohtsuki; Nobuharu Goto; Hirokazu Sugimoto; Hirotoshi Utsunomiya; Koji Oda; Eiji Warabi; Tetsuro Ishii; Masayuki Yamamoto
Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems.
Biochemical and biophysical research communications 2009;389(3):431-6.
2009: Narsa Reddy Machireddy; Vegiraju Suryanaraya; Melinda S Yates; Steven R Kleeberger; Paul M Hassoun; Masayuki Yamamoto; Karen T Liby; Michael B Sporn; Thomas W Kensler; SEKHAR POTHIREDDY
The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice.
American journal of respiratory and critical care medicine 2009;180(9):867-74.
2009: Soona Shin; Junko Wakabayashi; Melinda S Yates; Nobunao Wakabayashi; Patrick Dolan; Susan Aja; Karen T Liby; Michael B Sporn; Masayuki Yamamoto; Thomas W Kensler
Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-imidazolide.
European journal of pharmacology 2009;620(1-3):138-44.
2009: Narsa Reddy Machireddy; Vegiraju Suryanarayana; Dhan V Kalvakolanu; Masayuki Yamamoto; Thomas W Kensler; Paul M Hassoun; Steven R Kleeberger; SEKHAR POTHIREDDY
Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(7):4601-8.
2009: Ritsuko Shimizu; Eri Kobayashi; James Douglas Engel; Masayuki Yamamoto
Induction of hyperproliferative fetal megakaryopoiesis by an N-terminally truncated GATA1 mutant.
Genes to cells : devoted to molecular & cellular mechanisms 2009;14(9):1119-31.
2009: Castle J Funatake; Kana Ao; Takehiro Suzuki; Hikari Murai; Masayuki Yamamoto; Yoshiaki Fujii-Kuriyama; Nancy Kerkvliet; Keiko Nohara
Expression of constitutively-active aryl hydrocarbon receptor in T-cells enhances the down-regulation of CD62L, but does not alter expression of CD25 or suppress the allogeneic CTL response.
Journal of immunotoxicology 2009;6(3):194-203.
2009: Manchang Liu; Dmitry N Grigoryev; Michael T Crow; Mark Haas; Masayuki Yamamoto; SEKHAR POTHIREDDY; Hamid Rabb
Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice.
Kidney international 2009;76(3):277-85.
2009: Keiko Nohara; Takehiro Suzuki; Kana Ao; Hikari Murai; Yoshimi Miyamoto; Kaoru Inouye; Xiaoqing Pan; Hozumi Motohashi; Yoshiaki Fujii-Kuriyama; Masayuki Yamamoto; Chiharu Tohyama
Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-gamma production in mice but does not suppress T(h)2-cytokine production or antibody production.
International immunology 2009;21(7):769-77.
2009: Narsa Reddy Machireddy; Steven R Kleeberger; Thomas W Kensler; Masayuki Yamamoto; Paul M Hassoun; SEKHAR POTHIREDDY
Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):7264-71.
2009: Melinda S Yates; Quynh T Tran; Patrick Dolan; William O Osburn; Soona Shin; Colin C McCulloch; Jay B Silkworth; Keiko Taguchi; Masayuki Yamamoto; Charlotte R Williams; Karen T Liby; Michael B. Sporn; Thomas R Sutter; Thomas W Kensler
Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice.
Carcinogenesis 2009;30(6):1024-31.
2009: Shinsuke Homma; Yukio Ishii; Yuko Morishima; Tadahiro Yamadori; Yosuke Matsuno; Norihiro Haraguchi; Norihiro Kikuchi; Hiroaki Satoh; Tohru Sakamoto; Nobuyuki Hizawa; Ken Itoh; Masayuki Yamamoto
Nrf2 enhances cell proliferation and resistance to anticancer drugs in human lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(10):3423-32.
2009: Daisuke Nozawa; Norio Suzuki; Maki Kobayashi-Osaki; Xiaoqing Pan; James Douglas Engel; Masayuki Yamamoto
GATA2-dependent and region-specific regulation of Gata2 transcription in the mouse midbrain.
Genes to cells : devoted to molecular & cellular mechanisms 2009;14(5):569-82.
2009: Kanako Abe; Ritsuko Shimizu; Xiaoqing Pan; Hiromi Hamada; Hiroyuki Yoshikawa; Masayuki Yamamoto
Stem cells of GATA1-related leukemia undergo pernicious changes after 5-fluorouracil treatment.
Experimental hematology 2009;37(4):435-445.e1.
2009: Mikiko Suzuki; Takashi Moriguchi; Kinuko Ohneda; Masayuki Yamamoto
Differential contribution of the Gata1 gene hematopoietic enhancer to erythroid differentiation.
Molecular and cellular biology 2009;29(5):1163-75.
2009: Anju Singh; Guoyu Ling; Avvaru N Suhasini; Pingwu Zhang; Masayuki Yamamoto; Ana Navas-Acien; Gregory Cosgrove; Rubin M Tuder; Thomas W Kensler; WALTER WATSON; Shyam Biswal
Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs.
Free radical biology & medicine 2009;46(3):376-86.
2009: Thomas E Sussan; Tirumalai Rangasamy; David J Blake; Deepti Malhotra; Hazim El-Haddad; Djahida Bedja; Melinda S Yates; Ponvijay Kombairaju; Masayuki Yamamoto; Karen T Liby; Michael B. Sporn; Kathleen L Gabrielson; Hunter C Champion; Rubin M Tuder; Thomas W Kensler; Shyam Biswal
Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(1):250-5.
2008: Takashi Mamiya; Fumiki Katsuoka; Aki Hirayama; Osamu Nakajima; Akira Kobayashi; Jonathan M Maher; Hirofumi Matsui; Ichinosuke Hyodo; Masayuki Yamamoto; Tomonori Hosoya
Hepatocyte-specific deletion of heme oxygenase-1 disrupts redox homeostasis in basal and oxidative environments.
The Tohoku journal of experimental medicine 2008;216(4):331-9.
2008: Makiko Ohtsuji; Fumiki Katsuoka; Akira Kobayashi; Hiroyuki Aburatani; John D Hayes; Masayuki Yamamoto
Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes.
The Journal of biological chemistry 2008;283(48):33554-62.
2008: Keiko Hirota; Jun-ichi Sakamaki; Junji Ishida; Yoko Shimamoto; Shigeki Nishihara; Norio Kodama; Kazuhide Ohta; Masayuki Yamamoto; Keiji Tanimoto; Akiyoshi Fukamizu
A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding.
The Journal of biological chemistry 2008;283(47):32432-41.
2008: Masatsugu Ema; Daisuke Mori; Hitoshi Niwa; Yoshikazu Hasegawa; Yojiro Yamanaka; Seiji Hitoshi; Junsei Mimura; Yoh-ichi Kawabe; Tomohiro Hosoya; Masanobu Morita; Daisuke Shimosato; Kazuhiko Uchida; Norio Suzuki; Jun Yanagisawa; Kazuhiro Sogawa; Janet Rossant; Masayuki Yamamoto; Satoru Takahashi; Yoshiaki Fujii-Kuriyama
Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs.
Cell stem cell 2008;3(5):555-67.
2008: Narsa Reddy Machireddy; Steven R Kleeberger; Jay H Bream; P G Fallon; Thomas W Kensler; Masayuki Yamamoto; SEKHAR POTHIREDDY
Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling.
Oncogene 2008;27(44):5821-32.
2008: Marc A Williams; Tirumalai Rangasamy; Stephen M Bauer; Smruti Killedar; Matthew Karp; Thomas W Kensler; Masayuki Yamamoto; Patrick N Breysse; Shyam Biswal; Steve N Georas
Disruption of the transcription factor Nrf2 promotes pro-oxidative dendritic cells that stimulate Th2-like immunoresponsiveness upon activation by ambient particulate matter.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4545-59.
2008: Kit I Tong; Masayuki Yamamoto; Toshiyuki Tanaka
A simple method for amino acid selective isotope labeling of recombinant proteins in E. coli.
Journal of biomolecular NMR 2008;42(1):59-67.
2008: Tomomasa Yokomizo; Masatoshi Yanagida; Gang Huang; Motomi Osato; Chikako Honda; Masatsugu Ema; Satoru Takahashi; Masayuki Yamamoto; Yoshiaki Ito
Genetic evidence of PEBP2beta-independent activation of Runx1 in the murine embryo.
International journal of hematology 2008;88(2):134-8.
2008: William O Osburn; Melinda S Yates; Patrick Dolan; Sining Chen; Karen T Liby; Michael B. Sporn; Keiko Taguchi; Masayuki Yamamoto; Thomas W Kensler
Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice.
Toxicological sciences : an official journal of the Society of Toxicology 2008;104(1):218-27.
2008: L Shi; F Itoh; Susumu Itoh; Satoru Takahashi; Masayuki Yamamoto; M Kato
Ephrin-A1 promotes the malignant progression of intestinal tumors in Apc(min/+) mice.
Oncogene 2008;27(23):3265-73.
2008: Naoshi Obara; Norio Suzuki; Kibom Kim; Toshiro Nagasawa; Shigehiko Imagawa; Masayuki Yamamoto
Repression via the GATA box is essential for tissue-specific erythropoietin gene expression.
Blood 2008;111(10):5223-32.
2008: Keiko Taguchi; Megumi Shimada; Sayako Fujii; Daigo Sumi; Xiaoqing Pan; Shigeru Yamano; Takahito Nishiyama; Akira Hiratsuka; Masayuki Yamamoto; Arthur K Cho; John R Froines; Yoshito Kumagai
Redox cycling of 9,10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells.
Free radical biology & medicine 2008;44(8):1645-55.
2008: Tomomasa Yokomizo; Kazuteru Hasegawa; Hiroyuki Ishitobi; Motomi Osato; Masatsugu Ema; Yoshiaki Ito; Masayuki Yamamoto; Satoru Takahashi
Runx1 is involved in primitive erythropoiesis in the mouse.
Blood 2008;111(8):4075-80.
2008: William Brandt; Melin Khandekar; Norio Suzuki; Masayuki Yamamoto; Kim-Chew Lim; James Douglas Engel
Defining the functional boundaries of the Gata2 locus by rescue with a linked bacterial artificial chromosome transgene.
The Journal of biological chemistry 2008;283(14):8976-83.
2008: Ritsuko Shimizu; James Douglas Engel; Masayuki Yamamoto
GATA1-related leukaemias.
Nature reviews. Cancer 2008;8(4):279-87.
2008: Tomofumi Hoshino; Ritsuko Shimizu; Shinya Ohmori; Masumi Nagano; Xiaoqing Pan; Osamu Ohneda; Melin Khandekar; Masayuki Yamamoto; Kim-Chew Lim; James Douglas Engel
Reduced BMP4 abundance in Gata2 hypomorphic mutant mice result in uropathies resembling human CAKUT.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(2):159-70.
2008: Toshiharu Yamashita; Osamu Ohneda; Masumi Nagano; Motoyuki Iemitsu; Yuichi Makino; Hirotoshi Tanaka; Takashi Miyauchi; Katsutoshi Goto; Kinuko Ohneda; Yoshiaki Fujii-Kuriyama; Lorenz Poellinger; Masayuki Yamamoto
Abnormal heart development and lung remodeling in mice lacking the hypoxia-inducible factor-related basic helix-loop-helix PAS protein NEPAS.
Molecular and cellular biology 2008;28(4):1285-97.
2008: Shoko Saito; Kaoru Nouno; Ritsuko Shimizu; Masayuki Yamamoto; Kyosuke Nagata
Impairment of erythroid and megakaryocytic differentiation by a leukemia-associated and t(9;9)-derived fusion gene product, SET/TAF-Ibeta-CAN/Nup214.
Journal of cellular physiology 2008;214(2):322-33.
2008: Takafumi Suzuki; Vincent P Kelly; Hozumi Motohashi; Osamu Nakajima; Satoru Takahashi; Susumu Nishimura; Masayuki Yamamoto
Deletion of the selenocysteine tRNA gene in macrophages and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2.
The Journal of biological chemistry 2008;283(4):2021-30.
2008: Tomonori Hosoya; Nobuhiko Harada; Junsei Mimura; Hozumi Motohashi; Satoru Takahashi; Osamu Nakajima; Masanobu Morita; Shimako Kawauchi; Masayuki Yamamoto; Yoshiaki Fujii-Kuriyama
Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice.
Biochemical and biophysical research communications 2008;365(3):562-7.
2007: Paweł Jałoszyński; Soichiro Murata; Yasuhiro Shinkai; Satoru Takahashi; Yoshito Kumagai; Susumu Nishimura; Masayuki Yamamoto
Dysfunction of Nrf2 decreases KBrO3-induced oxidative DNA damage in Ogg1-null mice.
Biochemical and biophysical research communications 2007;364(4):966-71.
2007: Narsa Reddy Machireddy; Steven R Kleeberger; Masayuki Yamamoto; Thomas W Kensler; Catherine Scollick; Shyam Biswal; SEKHAR POTHIREDDY
Genetic dissection of the Nrf2-dependent redox signaling-regulated transcriptional programs of cell proliferation and cytoprotection.
Physiological genomics 2007;32(1):74-81.
2007: Srinivas Papaiahgari; Adi Yerrapureddy; Swetha R Reddy; Narsa Reddy Machireddy; Jeffrey M Dodd-o; Michael T Crow; Dmitry N Grigoryev; Kathleen C Barnes; Rubin M Tuder; Masayuki Yamamoto; Thomas W Kensler; Shyam Biswal; Wayne Mitzner; Paul M Hassoun; SEKHAR POTHIREDDY
Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice.
American journal of respiratory and critical care medicine 2007;176(12):1222-35.
2007: Motohiko Oshima; Junsei Mimura; Masayuki Yamamoto; Yoshiaki Fujii-Kuriyama
Molecular mechanism of transcriptional repression of AhR repressor involving ANKRA2, HDAC4, and HDAC5.
Biochemical and biophysical research communications 2007;364(2):276-82.
2007: Takashi Toyama; Daigo Sumi; Yasuhiro Shinkai; Akira Yasutake; Keiko Taguchi; Kit I Tong; Masayuki Yamamoto; Yoshito Kumagai
Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.
Biochemical and biophysical research communications 2007;363(3):645-50.
2007: Momoko Kimura; Tae Yamamoto; Jianyong Zhang; Ken Itoh; Motoki Kyo; Terue Kamiya; Hiroyuki Aburatani; Fumiki Katsuoka; hirofumi kurokawa; Toshiyuki Tanaka; Hozumi Motohashi; Masayuki Yamamoto
Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer.
The Journal of biological chemistry 2007;282(46):33681-90.
2007: Osamu Tanabe; Yannan Shen; Qinghui Liu; Andrew D Campbell; Takashi Kuroha; Masayuki Yamamoto; James Douglas Engel
The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription.
Genes & development 2007;21(21):2832-44.
2007: Kit I Tong; Balasundaram Padmanabhan; Akira Kobayashi; Chengwei Shang; Yosuke Hirotsu; Shigeyuki Yokoyama; Masayuki Yamamoto
Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response.
Molecular and cellular biology 2007;27(21):7511-21.
2007: William O Osburn; Baktiar O Karim; Patrick Dolan; Guosheng Liu; Masayuki Yamamoto; David L Huso; Thomas W Kensler
Increased colonic inflammatory injury and formation of aberrant crypt foci in Nrf2-deficient mice upon dextran sulfate treatment.
International journal of cancer. Journal international du cancer 2007;121(9):1883-91.
2007: Ritsuko Shimizu; Masayuki Yamamoto
[Function and gene expression regulation of GATA-1 and GATA-2 transcription].
Seikagaku. The Journal of Japanese Biochemical Society 2007;79(10):941-52.
2007: Yoriko Watai; Akira Kobayashi; Hiroko Nagase; Mio Mizukami; Justina McEvoy; Jeffrey D Singer; Ken Itoh; Masayuki Yamamoto
Subcellular localization and cytoplasmic complex status of endogenous Keap1.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(10):1163-78.
2007: Soona Shin; Nobunao Wakabayashi; Vikas Misra; Shyam Biswal; Gum Hwa Lee; Elin Agoston; Masayuki Yamamoto; Thomas W Kensler
NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis.
Molecular and cellular biology 2007;27(20):7188-97.
2007: Jian Wang; Jocelyn Fields; Chunying Zhao; John Langer; Rajesh K Thimmulappa; Thomas W Kensler; Masayuki Yamamoto; Shyam Biswal; Sylvain Dore
Role of Nrf2 in protection against intracerebral hemorrhage injury in mice.
Free radical biology & medicine 2007;43(3):408-14.
2007: Makoto Kobayashi; Masayuki Yamamoto
Regulation of GATA1 gene expression.
Journal of biochemistry 2007;142(1):1-10.
2007: Narsa Reddy Machireddy; Steven R Kleeberger; Hye-Youn Cho; Masayuki Yamamoto; Thomas W Kensler; Shyam Biswal; SEKHAR POTHIREDDY
Deficiency in Nrf2-GSH signaling impairs type II cell growth and enhances sensitivity to oxidants.
American journal of respiratory cell and molecular biology 2007;37(1):3-8.
2007: Zahoor Shah; Rung-chi Li; Rajesh K Thimmulappa; Thomas W Kensler; Masayuki Yamamoto; Shyam Biswal; Sylvain Dore
Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury.
Neuroscience 2007;147(1):53-9.
2007: Jianyong Zhang; Tomonori Hosoya; Atsushi Maruyama; Keizo Nishikawa; Jonathan M Maher; Tsutomu Ohta; Hozumi Motohashi; Akiyoshi Fukamizu; Shigeki Shibahara; Ken Itoh; Masayuki Yamamoto
Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.
The Biochemical journal 2007;404(3):459-66.
2007: Ritsuko Shimizu; Cecelia D Trainor; Keizo Nishikawa; Makoto Kobayashi; Kinuko Ohneda; Masayuki Yamamoto
GATA-1 self-association controls erythroid development in vivo.
The Journal of biological chemistry 2007;282(21):15862-71.
2007: Osamu Tanabe; David McPhee; Shoko Kobayashi; Yannan Shen; William Brandt; Xia Jiang; Andrew D Campbell; Yei-Tsung Chen; Chawn shang Chang; Masayuki Yamamoto; Keiji Tanimoto; James Douglas Engel
Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4.
The EMBO journal 2007;26(9):2295-306.
2007: Melin Khandekar; William Brandt; Yinghui Zhou; Susan L Dagenais; Thomas W Glover; Norio Suzuki; Ritsuko Shimizu; Masayuki Yamamoto; Kim-Chew Lim; James Douglas Engel
A Gata2 intronic enhancer confers its pan-endothelia-specific regulation.
Development (Cambridge, England) 2007;134(9):1703-12.
2007: Hozumi Motohashi; Masayuki Yamamoto
Carcinogenesis and transcriptional regulation through Maf recognition elements.
Cancer science 2007;98(2):135-9.
2007: Tomomasa Yokomizo; Satoru Takahashi; Naomi Mochizuki; Takashi Kuroha; Masatsugu Ema; Asami Wakamatsu; Ritsuko Shimizu; Osamu Ohneda; Motomi Osato; Hitoshi Okada; Toshihisa Komori; Minetaro Ogawa; Shin-Ichi Nishikawa; Yoshiaki Ito; Masayuki Yamamoto
Characterization of GATA-1(+) hemangioblastic cells in the mouse embryo.
The EMBO journal 2007;26(1):184-96.
2007: Melinda S Yates; Masafumi Tauchi; Fumiki Katsuoka; Kathleen C Flanders; Karen T Liby; Tadashi Honda; Gordon W Gribble; Delinda A Johnson; Jeffrey A Johnson; Neal C Burton; Tomás R Guilarte; Masayuki Yamamoto; Michael B. Sporn; Thomas W Kensler
Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.
Molecular cancer therapeutics 2007;6(1):154-62.
2006: Rajesh K Thimmulappa; Catherine Scollick; Kassim Traore; Melinda Yates; Michael A Trush; Karen T Liby; Michael B. Sporn; Masayuki Yamamoto; Thomas W Kensler; Shyam Biswal
Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide.
Biochemical and biophysical research communications 2006;351(4):883-9.
2006: Masatsugu Ema; Tomomasa Yokomizo; Asami Wakamatsu; Tsumoru Terunuma; Masayuki Yamamoto; Satoru Takahashi
Primitive erythropoiesis from mesodermal precursors expressing VE-cadherin, PECAM-1, Tie2, endoglin, and CD34 in the mouse embryo.
Blood 2006;108(13):4018-24.
2006: Hiroki Sekine; Junsei Mimura; Masayuki Yamamoto; Yoshiaki Fujii-Kuriyama
Unique and overlapping transcriptional roles of arylhydrocarbon receptor nuclear translocator (Arnt) and Arnt2 in xenobiotic and hypoxic responses.
The Journal of biological chemistry 2006;281(49):37507-16.
2006: Anju Singh; Tirumalai Rangasamy; Rajesh K Thimmulappa; Hannah Lee; William O Osburn; Regina Brigelius-Flohé; Thomas W Kensler; Masayuki Yamamoto; Shyam Biswal
Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2.
American journal of respiratory cell and molecular biology 2006;35(6):639-50.
2006: Harumi Y Mukai; Hozumi Motohashi; Osamu Ohneda; Norio Suzuki; Masumi Nagano; Masayuki Yamamoto
Transgene insertion in proximity to the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation.
Molecular and cellular biology 2006;26(21):7953-65.
2006: Jianyong Zhang; Tsutomu Ohta; Atsushi Maruyama; Tomonori Hosoya; Keizo Nishikawa; Jonathan M Maher; Shigeki Shibahara; Ken Itoh; Masayuki Yamamoto
BRG1 interacts with Nrf2 to selectively mediate HO-1 induction in response to oxidative stress.
Molecular and cellular biology 2006;26(21):7942-52.
2006: Ken Matsumoto; Shigehiko Imagawa; Naoshi Obara; Norio Suzuki; Satoru Takahashi; Toshiro Nagasawa; Masayuki Yamamoto
2-Oxoglutarate downregulates expression of vascular endothelial growth factor and erythropoietin through decreasing hypoxia-inducible factor-1alpha and inhibits angiogenesis.
Journal of cellular physiology 2006;209(2):333-40.
2006: Sakie Hosoya-Ohmura; Naomi Mochizuki; Mikiko Suzuki; Osamu Ohneda; Kinuko Ohneda; Masayuki Yamamoto
GATA-4 incompletely substitutes for GATA-1 in promoting both primitive and definitive erythropoiesis in vivo.
The Journal of biological chemistry 2006;281(43):32820-30.
2006: Kit I Tong; Akira Kobayashi; Fumiki Katsuoka; Masayuki Yamamoto
Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.
Biological chemistry 2006;387(10-11):1311-20.
2006: Takashi Moriguchi; Nakano Takako; Michito Hamada; Atsuko Maeda; Yuki Fujioka; Takashi Kuroha; Reuben E Huber; Susan L Hasegawa; Arvind Rao; Masayuki Yamamoto; Satoru Takahashi; Kim-Chew Lim; James Douglas Engel
Gata3 participates in a complex transcriptional feedback network to regulate sympathoadrenal differentiation.
Development (Cambridge, England) 2006;133(19):3871-81.
2006: Xiang Yu; Patricia A Egner; Junko Wakabayashi; Nobunao Wakabayashi; Masayuki Yamamoto; Thomas W Kensler
Nrf2-mediated induction of cytoprotective enzymes by 15-deoxy-Delta12,14-prostaglandin J2 is attenuated by alkenal/one oxidoreductase.
The Journal of biological chemistry 2006;281(36):26245-52.
2006: Takashi Moriguchi; Michito Hamada; Naoki Morito; Tsumoru Terunuma; Kazuteru Hasegawa; Chuan Zhang; Tomomasa Yokomizo; Ritsuko Esaki; Etsushi Kuroda; Keigyou Yoh; Takashi Kudo; Michio Nagata; David Greaves; James Douglas Engel; Masayuki Yamamoto; Satoru Takahashi
MafB is essential for renal development and F4/80 expression in macrophages.
Molecular and cellular biology 2006;26(15):5715-27.
2006: Mikiko Suzuki; Kinuko Ohneda; Sakie Hosoya-Ohmura; Saho Tsukamoto; Osamu Ohneda; Sjaak Philipsen; Masayuki Yamamoto
Real-time monitoring of stress erythropoiesis in vivo using Gata1 and beta-globin LCR luciferase transgenic mice.
Blood 2006;108(2):726-33.
2006: Hozumi Motohashi; Fumiki Katsuoka; Chika Miyoshi; Yasuhiro Uchimura; Hisato Saitoh; Claire Francastel; James Douglas Engel; Masayuki Yamamoto
MafG sumoylation is required for active transcriptional repression.
Molecular and cellular biology 2006;26(12):4652-63.
2006: Tae Yamamoto; Motoki Kyo; Terue Kamiya; Toshiyuki Tanaka; James Douglas Engel; Hozumi Motohashi; Masayuki Yamamoto
Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(6):575-91.
2006: Rajesh K Thimmulappa; Hannah Lee; Tirumalai Rangasamy; SEKHAR POTHIREDDY; Masayuki Yamamoto; Thomas W Kensler; Shyam Biswal
Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis.
The Journal of clinical investigation 2006;116(4):984-95.
2006: Kit I Tong; Yasutake Katoh; Hideki Kusunoki; Ken Itoh; Toshiyuki Tanaka; Masayuki Yamamoto
Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model.
Molecular and cellular biology 2006;26(8):2887-900.
2006: Kimio Satoh; Yutaka Kagaya; Makoto Nakano; Yoshitaka Ito; Jun Ohta; Hiroko Tada; Akihiko Karibe; Naoko Minegishi; Norio Suzuki; Masayuki Yamamoto; Masao Ono; Jun Watanabe; Kunio Shirato; Naoto Ishii; Kazuo Sugamura; Hiroaki Shimokawa
Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice.
Circulation 2006;113(11):1442-50.
2006: Balasundaram Padmanabhan; Kit I Tong; Tsutomu Ohta; Yoshihiro Nakamura; Maria Scharlock; Makiko Ohtsuji; MOON-IL KANG; Akira Kobayashi; Shigeyuki Yokoyama; Masayuki Yamamoto
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer.
Molecular cell 2006;21(5):689-700.
2006: Norio Suzuki; Osamu Ohneda; Naoko Minegishi; Mitsuo Nishikawa; Takayuki Ohta; Satoru Takahashi; James Douglas Engel; Masayuki Yamamoto
Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2202-7.
2006: Tohru Fujiwara; Hideo Harigae; Shinichiro Takahashi; Kazumichi Furuyama; Osamu Nakajima; Jiying Sun; Kazuhiko Igarashi; Masayuki Yamamoto; Shigeru Sassa; Mitsuo Kaku; Takeshi Sasaki
Differential gene expression profiling between wild-type and ALAS2-null erythroblasts: identification of novel heme-regulated genes.
Biochemical and biophysical research communications 2006;340(1):105-10.
2006: Haruko Nagai; Masato Kubo; Ryo Abe; Masayuki Yamamoto; Keiko Nohara
Constitutive activation of the aryl hydrocarbon receptor in T-lineage cells induces thymus involution independently of the Fas/Fas ligand signaling pathway.
International immunopharmacology 2006;6(2):279-86.
2006: Naoki Morito; Keigyou Yoh; Yuki Fujioka; Takako Nakano; Homare Shimohata; Yuko Hashimoto; Akiko Yamada; Atsuko Maeda; Fumihiko Matsuno; Hiroyuki Hata; Atsushi Suzuki; Shigehiko Imagawa; Hiroaki Mitsuya; Hiroyasu Esumi; Akio Koyama; Masayuki Yamamoto; Naoyoshi Mori; Satoru Takahashi
Overexpression of c-Maf contributes to T-cell lymphoma in both mice and human.
Cancer research 2006;66(2):812-9.
2006: Hiromi Okawa; Hozumi Motohashi; Akira Kobayashi; Hiroyuki Aburatani; Thomas W Kensler; Masayuki Yamamoto
Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.
Biochemical and biophysical research communications 2006;339(1):79-88.
2006: Makoto Kobayashi; Masayuki Yamamoto
Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species.
Advances in enzyme regulation 2006;46():113-40.
2006: Akira Kobayashi; MOON-IL KANG; Yoriko Watai; Kit I Tong; Takahiro Shibata; Koji Uchida; Masayuki Yamamoto
Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1.
Molecular and cellular biology 2006;26(1):221-9.
2005: Takashi Iizuka; Yukio Ishii; Ken Itoh; Takumi Kiwamoto; Toru Kimura; Yosuke Matsuno; Yuko Morishima; Ahmed E Hegab; Shinsuke Homma; Akihiro Nomura; Tohru Sakamoto; Masako Shimura; Aruto Yoshida; Masayuki Yamamoto; Kiyohisa Sekizawa
Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(12):1113-25.
2005: Hideki Kato; Junji Ishida; Shigehiko Imagawa; Tomoko Saito; Norio Suzuki; Toshiki Matsuoka; takeshi sugaya; Keiji Tanimoto; Takashi Yokoo; Osamu Ohneda; Fumihiro Sugiyama; Ken-ichi Yagami; Toshiro Fujita; Masayuki Yamamoto; Masaomi Nangaku; Akiyoshi Fukamizu
Enhanced erythropoiesis mediated by activation of the renin-angiotensin system via angiotensin II type 1a receptor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(14):2023-5.
2005: Yukio Ishii; Ken Itoh; Yuko Morishima; Toru Kimura; Takumi Kiwamoto; Takashi Iizuka; Ahmed E Hegab; Tomonori Hosoya; Akihiro Nomura; Tohru Sakamoto; Masayuki Yamamoto; Kiyohisa Sekizawa
Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6968-75.
2005: Akinori Yanaka; Masafumi Tauchi; Masayuki Yamamoto
[Effects of sulforaphane-rich broccoli sprouts on H. pylori-infected gastric mucosa].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 11():582-6.
2005: Masafumi Tauchi; Azumi Hida; Takaaki Negishi; Fumiki Katsuoka; Shuhei Noda; Junsei Mimura; Tomonori Hosoya; Akinori Yanaka; Hiroyuki Aburatani; Yoshiaki Fujii-Kuriyama; Hozumi Motohashi; Masayuki Yamamoto
Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions.
Molecular and cellular biology 2005;25(21):9360-8.
2005: Fumiki Katsuoka; Hozumi Motohashi; Tetsuro Ishii; Hiroyuki Aburatani; James Douglas Engel; Masayuki Yamamoto
Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes.
Molecular and cellular biology 2005;25(18):8044-51.
2005: Maki Kobayashi-Osaki; Osamu Ohneda; Norio Suzuki; Naoko Minegishi; Tomomasa Yokomizo; Satoru Takahashi; Kim-Chew Lim; James Douglas Engel; Masayuki Yamamoto
GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.
Molecular and cellular biology 2005;25(16):7005-20.
2005: Tomonori Hosoya; Atsushi Maruyama; MOON-IL KANG; Yukie Kawatani; Takahiro Shibata; Koji Uchida; Eiji Warabi; Noriko Noguchi; Ken Itoh; Masayuki Yamamoto
Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells.
The Journal of biological chemistry 2005;280(29):27244-50.
2005: Tirumalai Rangasamy; Jia Guo; Wayne Mitzner; Jesse Roman; Anju Singh; Allison Fryer; Masayuki Yamamoto; Thomas W Kensler; Rubin M Tuder; Steve N Georas; Shyam Biswal
Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice.
The Journal of experimental medicine 2005;202(1):47-59.
2005: Naoko Minegishi; Norio Suzuki; Yukie Kawatani; Ritsuko Shimizu; Masayuki Yamamoto
Rapid turnover of GATA-2 via ubiquitin-proteasome protein degradation pathway.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(7):693-704.
2005: Masatoshi Yanagida; Motomi Osato; Namiko Yamashita; Huang Liqun; Bindya Jacob; Feng Wu; Xinmin Cao; Takuro Nakamura; Tomomasa Yokomizo; Satoru Takahashi; Masayuki Yamamoto; Shigesada Katsuya; Yoshiaki Ito
Increased dosage of Runx1/AML1 acts as a positive modulator of myeloid leukemogenesis in BXH2 mice.
Oncogene 2005;24(28):4477-85.
2005: Xiaoqing Pan; Osamu Ohneda; Kinuko Ohneda; Fokke Lindeboom; Fumiko Iwata; Ritsuko Shimizu; Masumi Nagano; Naruyoshi Suwabe; Sjaak Philipsen; Kim-Chew Lim; James Douglas Engel; Masayuki Yamamoto
Graded levels of GATA-1 expression modulate survival, proliferation, and differentiation of erythroid progenitors.
The Journal of biological chemistry 2005;280(23):22385-94.
2005: Chuan Zhang; Takashi Moriguchi; Miwako Kajihara; Ritsuko Esaki; Ayako Harada; Homare Shimohata; Hisashi Oishi; Michito Hamada; Naoki Morito; Kazuteru Hasegawa; Takashi Kudo; James Douglas Engel; Masayuki Yamamoto; Satoru Takahashi
MafA is a key regulator of glucose-stimulated insulin secretion.
Molecular and cellular biology 2005;25(12):4969-76.
2005: Mie Mochizuki; Yukio Ishii; Ken Itoh; Takashi Iizuka; Yuko Morishima; Toru Kimura; Takumi Kiwamoto; Yosuke Matsuno; Ahmed E Hegab; Akihiro Nomura; Tohru Sakamoto; Koji Uchida; Masayuki Yamamoto; Kiyohisa Sekizawa
Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury.
American journal of respiratory and critical care medicine 2005;171(11):1260-6.
2005: Takafumi Suzuki; Yaeko Takagi; Hitoshi Osanai; Li Li; Miki Takeuchi; Yasutake Katoh; Makoto Kobayashi; Masayuki Yamamoto
Pi class glutathione S-transferase genes are regulated by Nrf 2 through an evolutionarily conserved regulatory element in zebrafish.
The Biochemical journal 2005;388(Pt 1):65-73.
2005: Vincent P Kelly; Takafumi Suzuki; Osamu Nakajima; Tsuyoshi Arai; Yoshitaka Tamai; Satoru Takahashi; Susumu Nishimura; Masayuki Yamamoto
The distal sequence element of the selenocysteine tRNA gene is a tissue-dependent enhancer essential for mouse embryogenesis.
Molecular and cellular biology 2005;25(9):3658-69.
2005: Keiko Nohara; Xiaoqing Pan; Shin-ichi Tsukumo; Azumi Hida; Tomohiro Ito; Haruko Nagai; Kaoru Inouye; Hozumi Motohashi; Masayuki Yamamoto; Yoshiaki Fujii-Kuriyama; Chiharu Tohyama
Constitutively active aryl hydrocarbon receptor expressed specifically in T-lineage cells causes thymus involution and suppresses the immunization-induced increase in splenocytes.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(5):2770-7.
2005: Makoto Kobayashi; Masayuki Yamamoto
Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation.
Antioxidants & redox signaling 2005;7(3-4):385-94.
2005: Fumiki Katsuoka; Hozumi Motohashi; James Douglas Engel; Masayuki Yamamoto
Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.
The Journal of biological chemistry 2005;280(6):4483-90.
2005: Ritsuko Shimizu; Masayuki Yamamoto
Gene expression regulation and domain function of hematopoietic GATA factors.
Seminars in cell & developmental biology 2005;16(1):129-36.
2005: Hye-Youn Cho; SEKHAR POTHIREDDY; Andrea Debiase; Masayuki Yamamoto; Steven R Kleeberger
Gene expression profiling of NRF2-mediated protection against oxidative injury.
Free radical biology & medicine 2005;38(3):325-43.
2005: Yasutake Katoh; Katsuyuki Iida; MOON-IL KANG; Akira Kobayashi; Mio Mizukami; Kit I Tong; Michael McMahon; John D Hayes; Ken Itoh; Masayuki Yamamoto
Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome.
Archives of biochemistry and biophysics 2005;433(2):342-50.
2005: Balasundaram Padmanabhan; Maria Scharlock; Kit I Tong; Yoshihiro Nakamura; MOON-IL KANG; Akira Kobayashi; Takehisa Matsumoto; Akiko Tanaka; Masayuki Yamamoto; Shigeyuki Yokoyama
Purification, crystallization and preliminary X-ray diffraction analysis of the Kelch-like motif region of mouse Keap1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 1):153-5.
2005: Akinori Yanaka; Songhua Zhang; Masafumi Tauchi; Hideo Suzuki; Takeshi Shibahara; Hirofumi Matsui; Akira Nakahara; Naomi Tanaka; Masayuki Yamamoto
Role of the nrf-2 gene in protection and repair of gastric mucosa against oxidative stress.
Inflammopharmacology 2005;13(1-3):83-90.
2005: Takeshi Nishio; Saburo Kawaguchi; Masayuki Yamamoto; Tsutomu Iseda; Takayuki Kawasaki; Takao Hase
Tenascin-C regulates proliferation and migration of cultured astrocytes in a scratch wound assay.
Neuroscience 2005;132(1):87-102.
2005: Mayu Nakano; Kinuko Ohneda; Harumi Yamamoto-Mukai; Ritsuko Shimizu; Osamu Ohneda; Sakie Ohmura; Mikiko Suzuki; Saho Tsukamoto; Toru Yanagawa; Hiroshi Yoshida; Yuichi Takakuwa; Masayuki Yamamoto
Transgenic over-expression of GATA-1 mutant lacking N-finger domain causes hemolytic syndrome in mouse erythroid cells.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(1):47-62.
2004: Yoko Nakano; Shigehiko Imagawa; Ken Matsumoto; Christian Stockmann; Naoshi Obara; Norio Suzuki; Takeshi Doi; Tatsuhiko Kodama; Satoru Takahashi; Toshiro Nagasawa; Masayuki Yamamoto
Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease.
Blood 2004;104(13):4300-7.
2004: Ritsuko Shimizu; Takashi Kuroha; Osamu Ohneda; Xiaoqing Pan; Kinuko Ohneda; Satoru Takahashi; Sjaak Philipsen; Masayuki Yamamoto
Leukemogenesis caused by incapacitated GATA-1 function.
Molecular and cellular biology 2004;24(24):10814-25.
2004: Melin Khandekar; Norio Suzuki; Jon Lewton; Masayuki Yamamoto; James Douglas Engel
Multiple, distant Gata2 enhancers specify temporally and tissue-specific patterning in the developing urogenital system.
Molecular and cellular biology 2004;24(23):10263-76.
2004: Tirumalai Rangasamy; Chung Y Cho; Rajesh K Thimmulappa; Lijie Zhen; Sorachai Srisuma; Thomas W Kensler; Masayuki Yamamoto; Irina Petrache; Rubin M Tuder; Shyam Biswal
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice.
The Journal of clinical investigation 2004;114(9):1248-59.
2004: Hozumi Motohashi; Masayuki Yamamoto
Nrf2-Keap1 defines a physiologically important stress response mechanism.
Trends in molecular medicine 2004;10(11):549-57.
2004: Tae Yamamoto; Keigyou Yoh; Akira Kobayashi; Yukio Ishii; Shigeo Kure; Akio Koyama; Tohru Sakamoto; Kiyohisa Sekizawa; Hozumi Motohashi; Masayuki Yamamoto
Identification of polymorphisms in the promoter region of the human NRF2 gene.
Biochemical and biophysical research communications 2004;321(1):72-9.
2004: Akira Kobayashi; MOON-IL KANG; Hiromi Okawa; Makiko Ohtsuji; Yukari Zenke; Tomoki Chiba; Kazuhiko Igarashi; Masayuki Yamamoto
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
Molecular and cellular biology 2004;24(16):7130-9.
2004: Hye-Youn Cho; SEKHAR POTHIREDDY; Masayuki Yamamoto; Steven R Kleeberger
The transcription factor NRF2 protects against pulmonary fibrosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(11):1258-60.
2004: Yaeko Takagi; Makoto Kobayashi; Li Li; Takafumi Suzuki; Keizo Nishikawa; Masayuki Yamamoto
MafT, a new member of the small Maf protein family in zebrafish.
Biochemical and biophysical research communications 2004;320(1):62-9.
2004: Toru Yanagawa; Ken Itoh; Junya Uwayama; Yasuaki Shibata; Akira Yamaguchi; Tsuneyoshi Sano; Tetsuro Ishii; Hiroshi Yoshida; Masayuki Yamamoto
Nrf2 deficiency causes tooth decolourization due to iron transport disorder in enamel organ.
Genes to cells : devoted to molecular & cellular mechanisms 2004;9(7):641-51.
2004: Tomohiro Ito; Shin-ichi Tsukumo; Norio Suzuki; Hozumi Motohashi; Masayuki Yamamoto; Yoshiaki Fujii-Kuriyama; Junsei Mimura; Tien-Min Lin; Richard E Peterson; Chiharu Tohyama; Keiko Nohara
A constitutively active arylhydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest.
The Journal of biological chemistry 2004;279(24):25204-10.
2004: Shosei Yoshida; Ayumi Takakura; Kazuyuki Ohbo; Kuniya Abe; Junko Wakabayashi; Masayuki Yamamoto; Toshio Suda; Yo-ichi Nabeshima
Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis.
Developmental biology 2004;269(2):447-58.
2004: Ken Itoh; Kit I Tong; Masayuki Yamamoto
Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles.
Free radical biology & medicine 2004;36(10):1208-13.
2004: Naoki Morito; Keigyou Yoh; Aki Hirayama; Ken Itoh; Masato Nose; Akio Koyama; Masayuki Yamamoto; Satoru Takahashi
Nrf2 deficiency improves autoimmune nephritis caused by the fas mutation lpr.
Kidney international 2004;65(5):1703-13.
2004: Hozumi Motohashi; Fumiki Katsuoka; James Douglas Engel; Masayuki Yamamoto
Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(17):6379-84.
2004: Ken Itoh; Masayuki Yamamoto
[Molecular mechanism of adaptive response to electrophiles].
Seikagaku. The Journal of Japanese Biochemical Society 2004;76(4):339-48.
2004: Ritsuko Shimizu; Kinuko Ohneda; James Douglas Engel; Cecelia D Trainor; Masayuki Yamamoto
Transgenic rescue of GATA-1-deficient mice with GATA-1 lacking a FOG-1 association site phenocopies patients with X-linked thrombocytopenia.
Blood 2004;103(7):2560-7.
2004: Tetsuro Ishii; Ken Itoh; Emilio Ruiz; David S Leake; Hiroyuki Unoki; Masayuki Yamamoto; Giovanni E Mann
Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal.
Circulation research 2004;94(5):609-16.
2004: MOON-IL KANG; Akira Kobayashi; Nobunao Wakabayashi; Sang Geon Kim; Masayuki Yamamoto
Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2046-51.
2004: Nobunao Wakabayashi; Albena T Dinkova-Kostova; W David Holtzclaw; MOON-IL KANG; Akira Kobayashi; Masayuki Yamamoto; Thomas W Kensler; Paul Talalay
Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2040-5.
2004: Akira Kobayashi; Tsutomu Ohta; Masayuki Yamamoto
Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes.
Methods in enzymology 2004;378():273-86.
2004: Shigehiko Imagawa; Y Yamaguchi; K Ogawa; Naoshi Obara; Norio Suzuki; Masayuki Yamamoto; Toshiro Nagasawa
Interleukin-6 and tumor necrosis factor-alpha in patients with obstructive sleep apnea-hypopnea syndrome.
Respiration; international review of thoracic diseases 2004;71(1):24-9.
2004: Ken Itoh; Mie Mochizuki; Yukio Ishii; Tetsuro Ishii; Takahiro Shibata; Yoshiyuki Kawamoto; Vincent Kelly; Kiyohisa Sekizawa; Koji Uchida; Masayuki Yamamoto
Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2).
Molecular and cellular biology 2004;24(1):36-45.
2003: Naoki Morito; Keigyou Yoh; Ken Itoh; Aki Hirayama; Akio Koyama; Masayuki Yamamoto; Satoru Takahashi
Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels.
Oncogene 2003;22(58):9275-81.
2003: Naoshi Obara; Shigehiko Imagawa; Yoko Nakano; Masayuki Yamamoto; Toshihiro Noguchi; Toshiro Nagasawa
Hematological aspects of a novel 9-aminoanthracycline, amrubicin.
Cancer science 2003;94(12):1104-6.
2003: Mi-Kyoung Kwak; Nobunao Wakabayashi; Jennifer L Greenlaw; Masayuki Yamamoto; Thomas W Kensler
Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway.
Molecular and cellular biology 2003;23(23):8786-94.
2003: Norio Suzuki; Naruyoshi Suwabe; Osamu Ohneda; Naoshi Obara; Shigehiko Imagawa; Xiaoqing Pan; Hozumi Motohashi; Masayuki Yamamoto
Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels.
Blood 2003;102(10):3575-83.
2003: Keizo Nishikawa; Makoto Kobayashi; Atsuko Masumi; Susan E Lyons; Brant M Weinstein; P Paul Liu; Masayuki Yamamoto
Self-association of Gata1 enhances transcriptional activity in vivo in zebra fish embryos.
Molecular and cellular biology 2003;23(22):8295-305.
2003: Nobunao Wakabayashi; Ken Itoh; Junko Wakabayashi; Hozumi Motohashi; Shuhei Noda; Satoru Takahashi; Sumihisa Imakado; Tomoe Kotsuji; Fujio Otsuka; Dennis R Roop; Takanori Harada; James Douglas Engel; Masayuki Yamamoto
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation.
Nature genetics 2003;35(3):238-45.
2003: Keigyou Yoh; Kazuko Shibuya; Naoki Morito; Takako Nakano; Kazusa Ishizaki; Homare Shimohata; Masato Nose; Shozo Izui; Akira Shibuya; Akio Koyama; James Douglas Engel; Masayuki Yamamoto; Satoru Takahashi
Transgenic overexpression of GATA-3 in T lymphocytes improves autoimmune glomerulonephritis in mice with a BXSB/MpJ-Yaa genetic background.
Journal of the American Society of Nephrology : JASN 2003;14(10):2494-502.
2003: Shigehiko Imagawa; Yoko Nakano; Naoshi Obara; Norio Suzuki; Takeshi Doi; Tatsuhiko Kodama; Toshiro Nagasawa; Masayuki Yamamoto
A GATA-specific inhibitor (K-7174) rescues anemia induced by IL-1beta, TNF-alpha, or L-NMMA.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(12):1742-4.
2003: Naoko Minegishi; Norio Suzuki; Tomomasa Yokomizo; Xiaoqing Pan; Tetsuhiro Fujimoto; Satoru Takahashi; Takahiko Hara; Atsushi Miyajima; Shin-Ichi Nishikawa; Masayuki Yamamoto
Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos.
Blood 2003;102(3):896-905.
2003: Junko Wakabayashi; Kentaro Yomogida; Osamu Nakajima; Keigyou Yoh; Satoru Takahashi; James Douglas Engel; Kinuko Ohneda; Masayuki Yamamoto
GATA-1 testis activation region is essential for Sertoli cell-specific expression of GATA-1 gene in transgenic mouse.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(7):619-30.
2003: Junko Aono; Toru Yanagawa; Ken Itoh; Baojie Li; Hiroshi Yoshida; Yoshito Kumagai; Masayuki Yamamoto; Tetsuro Ishii
Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts.
Biochemical and biophysical research communications 2003;305(2):271-7.
2003: Aki Hirayama; Keigyou Yoh; Sohji Nagase; Atsushi Ueda; Ken Itoh; Naoki Morito; Kouichi Hirayama; Satoru Takahashi; Masayuki Yamamoto; Akio Koyama
EPR imaging of reducing activity in Nrf2 transcriptional factor-deficient mice.
Free radical biology & medicine 2003;34(10):1236-42.
2003: Takashi Moriguchi; Hozumi Motohashi; Tomonori Hosoya; Osamu Nakajima; Satoru Takahashi; Seiichiroh Ohsako; Yasunobu Aoki; Noriko Nishimura; Chiharu Tohyama; Yoshiaki Fujii-Kuriyama; Masayuki Yamamoto
Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5652-7.
2003: Naoshi Obara; Shigehiko Imagawa; Yoko Nakano; Norio Suzuki; Masayuki Yamamoto; Toshiro Nagasawa
Suppression of erythropoietin gene expression by cadmium depends on inhibition of HIF-1, not stimulation of GATA-2.
Archives of toxicology 2003;77(5):267-73.
2003: Ken Itoh; Nobunao Wakabayashi; Yasutake Katoh; Tetsuro Ishii; Tania O'Connor; Masayuki Yamamoto
Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(4):379-91.
2003: Hisayuki Yokoyama; Hideo Harigae; Shinichiro Takahashi; Satoru Takahashi; Kazumichi Furuyama; Mitsuo Kaku; Masayuki Yamamoto; Takeshi Sasaki
Regulation of YB-1 gene expression by GATA transcription factors.
Biochemical and biophysical research communications 2003;303(1):140-5.
2003: Shuhei Noda; Nobuhiko Harada; Azumi Hida; Yoshiaki Fujii-Kuriyama; Hozumi Motohashi; Masayuki Yamamoto
Gene expression of detoxifying enzymes in AhR and Nrf2 compound null mutant mouse.
Biochemical and biophysical research communications 2003;303(1):105-11.
2003: Mi-Kyoung Kwak; Nobunao Wakabayashi; Ken Itoh; Hozumi Motohashi; Masayuki Yamamoto; Thomas W Kensler
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.
The Journal of biological chemistry 2003;278(10):8135-45.
2003: Minerva Ramos-Gomez; Patrick Dolan; Ken Itoh; Masayuki Yamamoto; Thomas W Kensler
Interactive effects of nrf2 genotype and oltipraz on benzo[a]pyrene-DNA adducts and tumor yield in mice.
Carcinogenesis 2003;24(3):461-7.
2003: Fumiki Katsuoka; Hozumi Motohashi; Yuna Tamagawa; Shigeo Kure; Kazuhiko Igarashi; James Douglas Engel; Masayuki Yamamoto
Small Maf compound mutants display central nervous system neuronal degeneration, aberrant transcription, and Bach protein mislocalization coincident with myoclonus and abnormal startle response.
Molecular and cellular biology 2003;23(4):1163-74.
2003: Hideo Harigae; Osamu Nakajima; Naruyoshi Suwabe; Hisayuki Yokoyama; Kazumichi Furuyama; Takeshi Sasaki; Mitsuo Kaku; Masayuki Yamamoto; Shigeru Sassa
Aberrant iron accumulation and oxidized status of erythroid-specific delta-aminolevulinate synthase (ALAS2)-deficient definitive erythroblasts.
Blood 2003;101(3):1188-93.
2002: Kinuko Ohneda; Ritsuko Shimizu; Shigeko Nishimura; Yasushi Muraosa; Satoru Takahashi; James Douglas Engel; Masayuki Yamamoto
A minigene containing four discrete cis elements recapitulates GATA-1 gene expression in vivo.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(12):1243-54.
2002: Kimitsune Ishizaki; Yuu Shimizu-Ueda; Sachiko Okada; Masayuki Yamamoto; Masaki Fujisawa; Katsuyuki T Yamato; Fukuzawa Hideya; Kanji Ohyama
Multicopy genes uniquely amplified in the Y chromosome-specific repeats of the liverwort Marchantia polymorpha.
Nucleic acids research 2002;30(21):4675-81.
2002: Norio Suzuki; Osamu Ohneda; Satoru Takahashi; Masato Higuchi; Harumi Y Mukai; Tatsutoshi Nakahata; Shigehiko Imagawa; Masayuki Yamamoto
Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality.
Blood 2002;100(7):2279-88.
2002: Rajesh K Thimmulappa; Kim H Mai; Sorachai Srisuma; Thomas W Kensler; Masayuki Yamamoto; Shyam Biswal
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.
Cancer research 2002;62(18):5196-203.
2002: Albena T Dinkova-Kostova; W David Holtzclaw; Robert N Cole; Ken Itoh; Nobunao Wakabayashi; Yasutake Katoh; Masayuki Yamamoto; Paul Talalay
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11908-13.
2002: Makoto Kobayashi; Ken Itoh; Takafumi Suzuki; Hitoshi Osanai; Keizo Nishikawa; Yasutake Katoh; Yaeko Takagi; Masayuki Yamamoto
Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(8):807-20.
2002: Hozumi Motohashi; Tania O'Connor; Fumiki Katsuoka; James Douglas Engel; Masayuki Yamamoto
Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors.
Gene 2002;294(1-2):1-12.
2002: Osamu Tanabe; Fumiki Katsuoka; Andrew D Campbell; Weimin Song; Masayuki Yamamoto; Keiji Tanimoto; James Douglas Engel
An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer.
The EMBO journal 2002;21(13):3434-42.
2002: Takashi Moriguchi; Takeshi Sakurai; Satoru Takahashi; Katsutoshi Goto; Masayuki Yamamoto
The human prepro-orexin gene regulatory region that activates gene expression in the lateral region and represses it in the medial regions of the hypothalamus.
The Journal of biological chemistry 2002;277(19):16985-92.
2002: Shigehiko Imagawa; Norio Suzuki; Ken Ohmine; Naoshi Obara; Harumi Y Mukai; Keiya Ozawa; Masayuki Yamamoto; Toshiro Nagasawa
GATA suppresses erythropoietin gene expression through GATA site in mouse erythropoietin gene promoter.
International journal of hematology 2002;75(4):376-81.
2002: Mi-Kyoung Kwak; Ken Itoh; Masayuki Yamamoto; Thomas W Kensler
Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter.
Molecular and cellular biology 2002;22(9):2883-92.
2002: Thein Tun; Hirotoshi Miyoshi; Tun Aung; Satoru Takahashi; Ritsuko Shimizu; Takashi Kuroha; Masayuki Yamamoto; Norio Ohshima
Effect of growth factors on ex vivo bone marrow cell expansion using three-dimensional matrix support.
Artificial organs 2002;26(4):333-9.
2002: Shigehiko Imagawa; Takahisa Tarumoto; Norio Suzuki; Harumi Y Mukai; Yuichi Hasegawa; Masato Higuchi; Tomohiro Neichi; Keiya Ozawa; Masayuki Yamamoto; Toshiro Nagasawa
L-arginine rescues decreased erythropoietin gene expression by stimulating GATA-2 with L-NMMA.
Kidney international 2002;61(2):396-404.
2002: Hye-Youn Cho; Anne E Jedlicka; SEKHAR POTHIREDDY; Thomas W Kensler; Masayuki Yamamoto; Liu-Yi Zhang; Steven R Kleeberger
Role of NRF2 in protection against hyperoxic lung injury in mice.
American journal of respiratory cell and molecular biology 2002;26(2):175-82.
2002: Kinuko Ohneda; Masayuki Yamamoto
Roles of hematopoietic transcription factors GATA-1 and GATA-2 in the development of red blood cell lineage.
Acta haematologica 2002;108(4):237-45.
2002: Tetsuro Ishii; Ken Itoh; Masayuki Yamamoto
Roles of Nrf2 in activation of antioxidant enzyme genes via antioxidant responsive elements.
Methods in enzymology 2002;348():182-90.
2001: Tetsuhiro Fujimoto; Minetaro Ogawa; Naoko Minegishi; Hiderou Yoshida; Tomomasa Yokomizo; Masayuki Yamamoto; Shin-Ichi Nishikawa
Step-wise divergence of primitive and definitive haematopoietic and endothelial cell lineages during embryonic stem cell differentiation.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(12):1113-27.
2001: Keigyou Yoh; T Sugawara; Hozumi Motohashi; Y Takahama; A Koyama; Masayuki Yamamoto; Satoru Takahashi
Transgenic over-expression of MafK suppresses T cell proliferation and function in vivo.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(12):1055-66.
2001: Yasutake Katoh; Ken Itoh; Eisaku Yoshida; Makoto Miyagishi; Akiyoshi Fukamizu; Masayuki Yamamoto
Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(10):857-68.
2001: Keigyou Yoh; Ken Itoh; A Enomoto; Aki Hirayama; N Yamaguchi; M Kobayashi; Naoki Morito; Akio Koyama; Masayuki Yamamoto; Satoru Takahashi
Nrf2-deficient female mice develop lupus-like autoimmune nephritis.
Kidney international 2001;60(4):1343-53.
2001: Ritsuko Shimizu; Satoru Takahashi; Kinuko Ohneda; James Douglas Engel; Masayuki Yamamoto
In vivo requirements for GATA-1 functional domains during primitive and definitive erythropoiesis.
The EMBO journal 2001;20(18):5250-60.
2001: Mi-Kyoung Kwak; Patricia A Egner; Patrick Dolan; Minerva Ramos-Gomez; John Groopman; Ken Itoh; Masayuki Yamamoto; Thomas W Kensler
Role of phase 2 enzyme induction in chemoprotection by dithiolethiones.
Mutation research 2001;480-481():305-15.
2001: Shigehiko Imagawa; Y Yamaguchi; Masato Higuchi; Tomohiro Neichi; Yuichi Hasegawa; Harumi Y Mukai; Norio Suzuki; Masayuki Yamamoto; Toshiro Nagasawa
Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea--hypopnea syndrome.
Blood 2001;98(4):1255-7.
2001: Yasunobu Aoki; H Sato; Noriko Nishimura; Shigeru Takahashi; K Itoh; Masayuki Yamamoto
Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust.
Toxicology and applied pharmacology 2001;173(3):154-60.
2001: Makoto Kobayashi; Keizo Nishikawa; Masayuki Yamamoto
Hematopoietic regulatory domain of gata1 gene is positively regulated by GATA1 protein in zebrafish embryos.
Development (Cambridge, England) 2001;128(12):2341-50.
2001: Yong-Chul Kim; Hiroshi Masutani; Yoshiaki Yamaguchi; Katsuhiko Itoh; Masayuki Yamamoto; Junji Yodoi
Hemin-induced activation of the thioredoxin gene by Nrf2. A differential regulation of the antioxidant responsive element by a switch of its binding factors.
The Journal of biological chemistry 2001;276(21):18399-406.
2001: Makoto Kobayashi; Keizo Nishikawa; T Suzuki; Masayuki Yamamoto
The homeobox protein Six3 interacts with the Groucho corepressor and acts as a transcriptional repressor in eye and forebrain formation.
Developmental biology 2001;232(2):315-26.
2001: Minerva Ramos-Gomez; Mi-Kyoung Kwak; Patrick Dolan; Ken Itoh; Masayuki Yamamoto; Paul Talalay; Thomas W Kensler
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3410-5.
2001: Mi-Kyoung Kwak; Ken Itoh; Masayuki Yamamoto; Thomas R Sutter; Thomas W Kensler
Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.
Molecular medicine (Cambridge, Mass.) 2001;7(2):135-45.
2001: M Tabata; Takahisa Tarumoto; Ken Ohmine; Y Furukawa; Kiyohiko Hatake; Keiya Ozawa; Yuichi Hasegawa; Harumi Y Mukai; Masayuki Yamamoto; Shigehiko Imagawa
Stimulation of GATA-2 as a mechanism of hydrogen peroxide suppression in hypoxia-induced erythropoietin gene expression.
Journal of cellular physiology 2001;186(2):260-7.
2000: Hozumi Motohashi; Fumiki Katsuoka; Jordan A Shavit; James Douglas Engel; Masayuki Yamamoto
Positive or negative MARE-dependent transcriptional regulation is determined by the abundance of small Maf proteins.
Cell 2000;103(6):865-75.
2000: Makoto Kobayashi; H Osanai; K Kawakami; Masayuki Yamamoto
Expression of three zebrafish Six4 genes in the cranial sensory placodes and the developing somites.
Mechanisms of development 2000;98(1-2):151-5.
2000: Takahisa Tarumoto; Shigehiko Imagawa; Ken Ohmine; Tadashi Nagai; Masato Higuchi; N Imai; Norio Suzuki; Masayuki Yamamoto; Keiya Ozawa
N(G)-monomethyl-L-arginine inhibits erythropoietin gene expression by stimulating GATA-2.
Blood 2000;96(5):1716-22.
2000: Yinghui Zhou; Masayuki Yamamoto; James Douglas Engel
GATA2 is required for the generation of V2 interneurons.
Development (Cambridge, England) 2000;127(17):3829-38.
2000: Masayuki Yamamoto; Osamu Nakajima
Animal models for X-linked sideroblastic anemia.
International journal of hematology 2000;72(2):157-64.
2000: Satoru Takahashi; Ritsuko Shimizu; Naruyoshi Suwabe; Takashi Kuroha; Keigyou Yoh; Jun Ohta; Susumu Nishimura; Kim-Chew Lim; James Douglas Engel; Masayuki Yamamoto
GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies.
Blood 2000;96(3):910-6.
2000: Satoru Takahashi; Kazumichi Furuyama; A Kobayashi; S Taketani; Hideo Harigae; Masayuki Yamamoto; K Igarashi; T Sasaki; Norio Hayashi
Cloning of a coproporphyrinogen oxidase promoter regulatory element binding protein.
Biochemical and biophysical research communications 2000;273(2):596-602.
2000: Masayuki Yamamoto; Osamu Nakajima; Kazumichi Furuyama; Hideo Harigae; Norio Hayashi
[Molecular diagnosis of hereditary sideroblastic anemia and model mouse of the disease].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2000;41(7):540-3.
2000: Fumiki Katsuoka; Hozumi Motohashi; K Onodera; Naruyoshi Suwabe; James Douglas Engel; Masayuki Yamamoto
One enhancer mediates mafK transcriptional activation in both hematopoietic and cardiac muscle cells.
The EMBO journal 2000;19(12):2980-91.
2000: Masayuki Yamamoto
[An approach to analyze transcription factor function in vivo utilizing specific gene regulatory regions].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(9 Suppl):1593-602.
2000: Masayuki Yamamoto
[Study of the transcription factor function in vivo: an overview].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(9 Suppl):1573-6.
2000: Tetsuro Ishii; Ken Itoh; Satoru Takahashi; H Sato; Toru Yanagawa; Yasutake Katoh; Shiro Bannai; Masayuki Yamamoto
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages.
The Journal of biological chemistry 2000;275(21):16023-9.
2000: H Hoshino; A Kobayashi; M Yoshida; N Kudo; T Oyake; H Motohashi; Norio Hayashi; Masayuki Yamamoto; Kazuhiko Igarashi
Oxidative stress abolishes leptomycin B-sensitive nuclear export of transcription repressor Bach2 that counteracts activation of Maf recognition element.
The Journal of biological chemistry 2000;275(20):15370-6.
2000: O Takeyama; Iwao Ikai; Masayuki Yamamoto; Akiyoshi Kanazawa; T Yagi; Takehiko Uesugi; Ryuta Nishitai; Seiji Satoh; Hiroaki Terajima; Yoshio Yamaoka
The protective role of Kupffer cells in humoral injury of xenoperfused rat livers.
Transplantation 2000;69(7):1283-9.
2000: K Onodera; Jordan A Shavit; Hozumi Motohashi; Masayuki Yamamoto; James Douglas Engel
Perinatal synthetic lethality and hematopoietic defects in compound mafG::mafK mutant mice.
The EMBO journal 2000;19(6):1335-45.
2000: A Kobayashi; H Yamagiwa; H Hoshino; Akihiko Muto; K Sato; M Morita; Norio Hayashi; Masayuki Yamamoto; Kazuhiko Igarashi
A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domain.
Molecular and cellular biology 2000;20(5):1733-46.
2000: X Pan; Naoko Minegishi; Hideo Harigae; H Yamagiwa; Masayoshi Minegishi; Y Akine; Masayuki Yamamoto
Identification of human GATA-2 gene distal IS exon and its expression in hematopoietic stem cell fractions.
Journal of biochemistry 2000;127(1):105-12.
2000: Susumu Nishimura; Satoru Takahashi; Takashi Kuroha; Naruyoshi Suwabe; Toshiro Nagasawa; Cecelia D Trainor; Masayuki Yamamoto
A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene.
Molecular and cellular biology 2000;20(2):713-23.
1999: Yasuhide Ishikawa; Yoshie Yamamoto; Makoto Kume; Kazuhiko Yamagami; H Yamamoto; S Kimoto; Y Sakai; Masayuki Yamamoto; Yoshio Yamaoka
Heat shock preconditioning on mitochondria during warm ischemia in rat livers.
The Journal of surgical research 1999;87(2):178-84.
1999: Osamu Nakajima; Satoru Takahashi; Hideo Harigae; Kazumichi Furuyama; Norio Hayashi; Shigeru Sassa; Masayuki Yamamoto
Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload.
The EMBO journal 1999;18(22):6282-9.
1999: C Yoshida; F Tokumasu; Ken-Ichi Hohmura; Jörg Bungert; Norio Hayashi; T Nagasawa; James Douglas Engel; Masayuki Yamamoto; Kunio Takeyasu; Kazuhiko Igarashi
Long range interaction of cis-DNA elements mediated by architectural transcription factor Bach1.
Genes to cells : devoted to molecular & cellular mechanisms 1999;4(11):643-55.
1999: Ken Itoh; Masayuki Yamamoto
[Transcriptional regulation of the phase II drug detoxifying enzyme genes].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(15 Suppl):2370-6.
1999: Masayuki Yamamoto
[Transcriptional regulation of detoxication enzyme genes: overview].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(15 Suppl):2368-9.
1999: Masayuki Yamamoto
[Present status and future aspects on study of molecular mechanisms of animal physiological adaptation to the environment].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(15 Suppl):2366-7.
1999: Ken Itoh; Tetsuro Ishii; Nobunao Wakabayashi; Masayuki Yamamoto
Regulatory mechanisms of cellular response to oxidative stress.
Free radical research 1999;31(4):319-24.
1999: K Onodera; Jordan A Shavit; Hozumi Motohashi; Fumiki Katsuoka; J E Akasaka; James Douglas Engel; Masayuki Yamamoto
Characterization of the murine mafF gene.
The Journal of biological chemistry 1999;274(30):21162-9.
1999: S Kawauchi; Satoru Takahashi; Osamu Nakajima; H Ogino; M Morita; M Nishizawa; K Yasuda; Masayuki Yamamoto
Regulation of lens fiber cell differentiation by transcription factor c-Maf.
The Journal of biological chemistry 1999;274(27):19254-60.
1999: Hideo Harigae; Kazumichi Furuyama; A Kimura; K Neriishi; N Tahara; M Kondo; N Hayashi; Masayuki Yamamoto; Shigeru Sassa; T Sasaki
A novel mutation of the erythroid-specific delta-aminolaevulinate synthase gene in a patient with X-linked sideroblastic anaemia.
British journal of haematology 1999;106(1):175-7.
1999: Naoko Minegishi; Jun Ohta; H Yamagiwa; Norio Suzuki; S Kawauchi; Yinghui Zhou; Satoru Takahashi; Norio Hayashi; James Douglas Engel; Masayuki Yamamoto
The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region.
Blood 1999;93(12):4196-207.
1999: Masayuki Yamamoto; M Fujinuma; M Tanaka; Ursula C Dräger; Peter McCaffery
Sagittal band expression of COUP-TF2 gene in the developing cerebellum.
Mechanisms of development 1999;84(1-2):143-6.
1999: A Kobayashi; E Ito; T Toki; K Kogame; Satoru Takahashi; Kazuhiko Igarashi; Norio Hayashi; Masayuki Yamamoto
Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3.
The Journal of biological chemistry 1999;274(10):6443-52.
1999: Ken Itoh; Nobunao Wakabayashi; Yasutake Katoh; Tetsuro Ishii; Kazuhiko Igarashi; James Douglas Engel; Masayuki Yamamoto
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain.
Genes & development 1999;13(1):76-86.
1998: Akiyoshi Kanazawa; Akira Tanaka; Shingo Iwata; Seiji Satoh; Etsuro Hatano; H Shinohara; Toshiyuki Kitai; Shoji Tsunekawa; Iwao Ikai; Masayuki Yamamoto; Rei Takahashi; Britton Chance; Yoshio Yamaoka
The beneficial effect of phosphocreatine accumulation in the creatine kinase transgenic mouse liver in endotoxin-induced hepatic cell death.
The Journal of surgical research 1998;80(2):229-35.
1998: Kazumichi Furuyama; R Uno; A Urabe; Norio Hayashi; H Fujita; M Kondo; S Sassa; Masayuki Yamamoto
R411C mutation of the ALAS2 gene encodes a pyridoxine-responsive enzyme with low activity.
British journal of haematology 1998;103(3):839-41.
1998: Naruyoshi Suwabe; Satoru Takahashi; T Nakano; Masayuki Yamamoto
GATA-1 regulates growth and differentiation of definitive erythroid lineage cells during in vitro ES cell differentiation.
Blood 1998;92(11):4108-18.
1998: Yinghui Zhou; Kim-Chew Lim; K Onodera; Satoru Takahashi; Jun Ohta; Naoko Minegishi; F Y Tsai; Stuart H Orkin; Masayuki Yamamoto; James Douglas Engel
Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital development.
The EMBO journal 1998;17(22):6689-700.
1998: Satoru Takahashi; S Taketani; J E Akasaka; A Kobayashi; Norio Hayashi; Masayuki Yamamoto; T Nagai
Differential regulation of coproporphyrinogen oxidase gene between erythroid and nonerythroid cells.
Blood 1998;92(9):3436-44.
1998: Hozumi Motohashi; J Ohta; James Douglas Engel; Masayuki Yamamoto
A core region of the mafK gene IN promoter directs neurone-specific transcription in vivo.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(10):671-84.
1998: Akihiko Muto; H Hoshino; L Madisen; N Yanai; M Obinata; Hajime Karasuyama; Norio Hayashi; H Nakauchi; Masayuki Yamamoto; Mark Groudine; Kazuhiko Igarashi
Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3' enhancer.
The EMBO journal 1998;17(19):5734-43.
1998: Kazuhiko Yamagami; Yoshie Yamamoto; Makoto Kume; S Kimoto; H Yamamoto; N Ozaki; Masayuki Yamamoto; Yasuyuki Shimahara; Shinya Toyokuni; Yoshio Yamaoka
Heat shock preconditioning ameliorates liver injury following normothermic ischemia-reperfusion in steatotic rat livers.
The Journal of surgical research 1998;79(1):47-53.
1998: C L Dai; Makoto Kume; Yoshie Yamamoto; Kazuhiko Yamagami; H Yamamoto; H Nakayama; N Ozaki; A M James Shapiro; Masayuki Yamamoto; Yoshio Yamaoka
Heat shock protein 72 production in liver tissue after experimental total hepatic inflow occlusion.
The British journal of surgery 1998;85(8):1061-5.
1998: Jordan A Shavit; Hozumi Motohashi; K Onodera; J Akasaka; Masayuki Yamamoto; James Douglas Engel
Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice.
Genes & development 1998;12(14):2164-74.
1998: Satoru Takahashi; Takuya Komeno; Naruyoshi Suwabe; Keigyou Yoh; Osamu Nakajima; Susumu Nishimura; Takashi Kuroha; Toshiro Nagasawa; Masayuki Yamamoto
Role of GATA-1 in proliferation and differentiation of definitive erythroid and megakaryocytic cells in vivo.
Blood 1998;92(2):434-42.
1998: Kazuhiko Igarashi; H Hoshino; A Muto; Naruyoshi Suwabe; Shin-Ichi Nishikawa; Hiromitsu Nakauchi; Masayuki Yamamoto
Multivalent DNA binding complex generated by small Maf and Bach1 as a possible biochemical basis for beta-globin locus control region complex.
The Journal of biological chemistry 1998;273(19):11783-90.
1998: Takashi Kuroha; Satoru Takahashi; Takuya Komeno; Ken Itoh; Toshiro Nagasawa; Masayuki Yamamoto
Ablation of Nrf2 function does not increase the erythroid or megakaryocytic cell lineage dysfunction caused by p45 NF-E2 gene disruption.
Journal of biochemistry 1998;123(3):376-9.
1998: Tadashi Nagai; K Igarashi; J Akasaka; Kazumichi Furuyama; H Fujita; N Hayashi; Masayuki Yamamoto; Shigeru Sassa
Regulation of NF-E2 activity in erythroleukemia cell differentiation.
The Journal of biological chemistry 1998;273(9):5358-65.
1998: Naoko Minegishi; Jun Ohta; Naruyoshi Suwabe; Hiromitsu Nakauchi; H Ishihara; Norio Hayashi; Masayuki Yamamoto
Alternative promoters regulate transcription of the mouse GATA-2 gene.
The Journal of biological chemistry 1998;273(6):3625-34.
1998: Hideo Harigae; Naruyoshi Suwabe; PH Weinstock; M Nagai; H Fujita; Masayuki Yamamoto; Shigeru Sassa
Deficient heme and globin synthesis in embryonic stem cells lacking the erythroid-specific delta-aminolevulinate synthase gene.
Blood 1998;91(3):798-805.
1998: Hideo Harigae; Satoru Takahashi; Naruyoshi Suwabe; H Ohtsu; L Gu; Z Yang; F Y Tsai; Y Kitamura; James Douglas Engel; Masayuki Yamamoto
Differential roles of GATA-1 and GATA-2 in growth and differentiation of mast cells.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(1):39-50.
1997: T Yagi; Iwao Ikai; Hiroaki Terajima; Seiji Satoh; Akiyoshi Kanazawa; H Shinohara; Takehiko Uesugi; T Yoneyama; T Gomi; Rei Takahashi; Masayuki Yamamoto; Takashi Inamoto; Yoshio Yamaoka
The protective effects of prostaglandin E1 on sinusoidal endothelial cells in xenogeneic pig liver perfusion.
The Journal of surgical research 1997;73(1):28-34.
1997: Masayuki Yamamoto; N Sato; H Tajima; K Furuke; Akihiro Ohira; Yoshihito Honda; Junji Yodoi
Induction of human thioredoxin in cultured human retinal pigment epithelial cells through cyclic AMP-dependent pathway; involvement in the cytoprotective activity of prostaglandin E1.
Experimental eye research 1997;65(5):645-52.
1997: Seiji Satoh; Hiroaki Terajima; T Yagi; Akiyoshi Kanazawa; H Shinohara; T Gomi; Takehiko Uesugi; T Yoneyama; Iwao Ikai; Rei Takahashi; Masayuki Yamamoto; Yoshio Yamaoka
Humoral injury in porcine livers perfused with human whole blood.
Transplantation 1997;64(8):1117-23.
1997: Hozumi Motohashi; Jordan A Shavit; Kazuhiko Igarashi; Masayuki Yamamoto; James Douglas Engel
The world according to Maf.
Nucleic acids research 1997;25(15):2953-59.
1997: Ken Itoh; T Chiba; Satoru Takahashi; Tetsuro Ishii; Kazuhiko Igarashi; Yasutake Katoh; T Oyake; Norio Hayashi; K Satoh; I Hatayama; Masayuki Yamamoto; Y Nabeshima
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
Biochemical and biophysical research communications 1997;236(2):313-22.
1997: Kazumichi Furuyama; H Fujita; T Nagai; K Yomogida; Hiroshi Munakata; M Kondo; A Kimura; A Kuramoto; Norio Hayashi; Masayuki Yamamoto
Pyridoxine refractory X-linked sideroblastic anemia caused by a point mutation in the erythroid 5-aminolevulinate synthase gene.
Blood 1997;90(2):822-30.
1997: Masayuki Yamamoto; Tasuku Honjo; MB Paumen
[Fatty acids-induced apoptosis].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(10 Suppl):1637-43.
1997: Satoru Takahashi; K Onodera; Hozumi Motohashi; Naruyoshi Suwabe; Norio Hayashi; N Yanai; Y Nabesima; Masayuki Yamamoto
Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene.
The Journal of biological chemistry 1997;272(19):12611-5.
1997: K Onodera; Satoru Takahashi; S Nishimura; J Ohta; H Motohashi; K Yomogida; Norio Hayashi; James Douglas Engel; Masayuki Yamamoto
GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4487-92.
1997: M Nagai; Tadashi Nagai; Masayuki Yamamoto; K Goto; T R Bishop; N Hayashi; H Kondo; Y Seyama; K Kano; H Fujita; Shigeru Sassa
Novel regulation of delta-aminolevulinate synthase in the rat harderian gland.
Biochemical pharmacology 1997;53(5):643-50.
1997: T Nagai; Hideo Harigae; Kazumichi Furuyama; Hiroshi Munakata; Norio Hayashi; K Endo; S Sassa; Masayuki Yamamoto
5-Aminolevulinate synthase expression and hemoglobin synthesis in a human myelogenous leukemia cell line.
Journal of biochemistry 1997;121(3):487-95.
1997: Hiroaki Terajima; Y Shirakata; T Yagi; S Mashima; H Shinohara; Seiji Satoh; Y Arima; T Gomi; Tetsuro Hirose; Rei Takahashi; Iwao Ikai; T Morimoto; Takashi Inamoto; Masayuki Yamamoto; Yoshio Yamaoka
Successful long-term xenoperfusion of the pig liver: continuous administration of prostaglandin E1 and insulin.
Transplantation 1997;63(4):507-12.
1997: MB Paumen; Yoko Ishida; Masamichi Muramatsu; Masayuki Yamamoto; Tasuku Honjo
Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis.
The Journal of biological chemistry 1997;272(6):3324-9.
1997: Masayuki Yamamoto; Satoru Takahashi; K Onodera; Yasushi Muraosa; James Douglas Engel
Upstream and downstream of erythroid transcription factor GATA-1.
Genes to cells : devoted to molecular & cellular mechanisms 1997;2(2):107-15.
1997: K Onodera; K Yomogida; Naruyoshi Suwabe; Satoru Takahashi; Yasushi Muraosa; Norio Hayashi; E Ito; L Gu; M Rassoulzadegan; James Douglas Engel; Masayuki Yamamoto
Conserved structure, regulatory elements, and transcriptional regulation from the GATA-1 gene testis promoter.
Journal of biochemistry 1997;121(2):251-63.
1997: Masayuki Yamamoto; Akihiro Ohira; O Honda; N Sato; K Furuke; Junji Yodoi; Yoshihito Honda
Analysis of localization of adult T-cell leukemia-derived factor in the transient ischemic rat retina after treatment with OP-1206 alpha-CD, a prostaglandin E1 analogue.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1997;45(1):63-70.
1996: Masayuki Yamamoto; Kikuya Kato; Yoshito Ikada
Effect of the structure of bone morphogenetic protein carriers on ectopic bone regeneration.
Tissue engineering 1996;2(4):315-26.