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Masayuki Yamamoto

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Oxidative Stress

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Publications

TOP 3
Okada Kosuke; Shoda Junichi; Taguchi Keiko; Maher Jonathan M; Ishizaki Kaoru; Inoue Yoshimi; Ohtsuki Makio; Goto Nobuharu; Sugimoto Hirokazu; Utsunomiya Hirotoshi; Oda Koji; Warabi Eiji; Ishii Tetsuro; Yamamoto Masayuki
Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems.
Reddy Narsa M; Suryanaraya Vegiraju; Yates Melinda S; Kleeberger Steven R; Hassoun Paul M; Yamamoto Masayuki; Liby Karen T; Sporn Michael B; Kensler Thomas W; Reddy Sekhar P
The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice.
Reddy Narsa M; Suryanarayana Vegiraju; Kalvakolanu Dhananjaya V; Yamamoto Masayuki; Kensler Thomas W; Hassoun Paul M; Kleeberger Steven R; Reddy Sekhar P
Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice.

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All Publications

2009: Okada Kosuke; Shoda Junichi; Taguchi Keiko; Maher Jonathan M; Ishizaki Kaoru; Inoue Yoshimi; Ohtsuki Makio; Goto Nobuharu; Sugimoto Hirokazu; Utsunomiya Hirotoshi; Oda Koji; Warabi Eiji; Ishii Tetsuro; Yamamoto Masayuki
Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems.
Biochemical and biophysical research communications 2009;389(3):431-6.
2009: Reddy Narsa M; Suryanaraya Vegiraju; Yates Melinda S; Kleeberger Steven R; Hassoun Paul M; Yamamoto Masayuki; Liby Karen T; Sporn Michael B; Kensler Thomas W; Reddy Sekhar P
The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice.
American journal of respiratory and critical care medicine 2009;180(9):867-74.
2009: Reddy Narsa M; Suryanarayana Vegiraju; Kalvakolanu Dhananjaya V; Yamamoto Masayuki; Kensler Thomas W; Hassoun Paul M; Kleeberger Steven R; Reddy Sekhar P
Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(7):4601-8.
2009: Shin Soona; Wakabayashi Junko; Yates Melinda S; Wakabayashi Nobunao; Dolan Patrick M; Aja Susan; Liby Karen T; Sporn Michael B; Yamamoto Masayuki; Kensler Thomas W
Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide.
European journal of pharmacology 2009;620(1-3):138-44.
2009: Shimizu Ritsuko; Kobayashi Eri; Engel James Douglas; Yamamoto Masayuki
Induction of hyperproliferative fetal megakaryopoiesis by an N-terminally truncated GATA1 mutant.
Genes to cells : devoted to molecular & cellular mechanisms 2009;14(9):1119-31.
2009: Funatake Castle J; Ao Kana; Suzuki Takehiro; Murai Hikari; Yamamoto Masayuki; Fujii-Kuriyama Yoshiaki; Kerkvliet Nancy I; Nohara Keiko
Expression of constitutively-active aryl hydrocarbon receptor in T-cells enhances the down-regulation of CD62L, but does not alter expression of CD25 or suppress the allogeneic CTL response.
Journal of immunotoxicology 2009;6(3):194-203.
2009: Liu Manchang; Grigoryev Dmitry N; Crow Michael T; Haas Mark; Yamamoto Masayuki; Reddy Sekhar P; Rabb Hamid
Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice.
Kidney international 2009;76(3):277-85.
2009: Nohara Keiko; Suzuki Takehiro; Ao Kana; Murai Hikari; Miyamoto Yoshimi; Inouye Kaoru; Pan Xiaoqing; Motohashi Hozumi; Fujii-Kuriyama Yoshiaki; Yamamoto Masayuki; Tohyama Chiharu
Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-gamma production in mice but does not suppress T(h)2-cytokine production or antibody production.
International immunology 2009;21(7):769-77.
2009: Reddy Narsa M; Kleeberger Steven R; Kensler Thomas W; Yamamoto Masayuki; Hassoun Paul M; Reddy Sekhar P
Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):7264-71.
2009: Yates Melinda S; Tran Quynh T; Dolan Patrick M; Osburn William O; Shin Soona; McCulloch Colin C; Silkworth Jay B; Taguchi Keiko; Yamamoto Masayuki; Williams Charlotte R; Liby Karen T; Sporn Michael B; Sutter Thomas R; Kensler Thomas W
Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice.
Carcinogenesis 2009;30(6):1024-31.
2009: Homma Shinsuke; Ishii Yukio; Morishima Yuko; Yamadori Tadahiro; Matsuno Yosuke; Haraguchi Norihiro; Kikuchi Norihiro; Satoh Hiroaki; Sakamoto Tohru; Hizawa Nobuyuki; Itoh Ken; Yamamoto Masayuki
Nrf2 enhances cell proliferation and resistance to anticancer drugs in human lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(10):3423-32.
2009: Nozawa Daisuke; Suzuki Norio; Kobayashi-Osaki Maki; Pan Xiaoqing; Engel James Douglas; Yamamoto Masayuki
GATA2-dependent and region-specific regulation of Gata2 transcription in the mouse midbrain.
Genes to cells : devoted to molecular & cellular mechanisms 2009;14(5):569-82.
2009: Abe Kanako; Shimizu Ritsuko; Pan Xiaoqing; Hamada Hiromi; Yoshikawa Hiroyuki; Yamamoto Masayuki
Stem cells of GATA1-related leukemia undergo pernicious changes after 5-fluorouracil treatment.
Experimental hematology 2009;37(4):435-445.e1.
2009: Suzuki Mikiko; Moriguchi Takashi; Ohneda Kinuko; Yamamoto Masayuki
Differential contribution of the Gata1 gene hematopoietic enhancer to erythroid differentiation.
Molecular and cellular biology 2009;29(5):1163-75.
2009: Singh Anju; Ling Guoyu; Suhasini Avvaru N; Zhang Ping; Yamamoto Masayuki; Navas-Acien Ana; Cosgrove Gregory; Tuder Rubin M; Kensler Thomas W; Watson Walter H; Biswal Shyam
Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs.
Free radical biology & medicine 2009;46(3):376-86.
2009: Sussan Thomas E; Rangasamy Tirumalai; Blake David J; Malhotra Deepti; El-Haddad Hazim; Bedja Djahida; Yates Melinda S; Kombairaju Ponvijay; Yamamoto Masayuki; Liby Karen T; Sporn Michael B; Gabrielson Kathleen L; Champion Hunter C; Tuder Rubin M; Kensler Thomas W; Biswal Shyam
Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(1):250-5.
2008: Mamiya Takashi; Katsuoka Fumiki; Hirayama Aki; Nakajima Osamu; Kobayashi Akira; Maher Jonathan M; Matsui Hirofumi; Hyodo Ichinosuke; Yamamoto Masayuki; Hosoya Tomonori
Hepatocyte-specific deletion of heme oxygenase-1 disrupts redox homeostasis in basal and oxidative environments.
The Tohoku journal of experimental medicine 2008;216(4):331-9.
2008: Ema Masatsugu; Mori Daisuke; Niwa Hitoshi; Hasegawa Yoshikazu; Yamanaka Yojiro; Hitoshi Seiji; Mimura Junsei; Kawabe Yoh-ichi; Hosoya Tomohiro; Morita Masanobu; Shimosato Daisuke; Uchida Kazuhiko; Suzuki Norio; Yanagisawa Jun; Sogawa Kazuhiro; Rossant Janet; Yamamoto Masayuki; Takahashi Satoru; Fujii-Kuriyama Yoshiaki
Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs.
Cell stem cell 2008;3(5):555-67.
2008: Ohtsuji Makiko; Katsuoka Fumiki; Kobayashi Akira; Aburatani Hiroyuki; Hayes John D; Yamamoto Masayuki
Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes.
The Journal of biological chemistry 2008;283(48):33554-62.
2008: Hirota Keiko; Sakamaki Jun-ichi; Ishida Junji; Shimamoto Yoko; Nishihara Shigeki; Kodama Norio; Ohta Kazuhide; Yamamoto Masayuki; Tanimoto Keiji; Fukamizu Akiyoshi
A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding.
The Journal of biological chemistry 2008;283(47):32432-41.
2008: Williams Marc A; Rangasamy Tirumalai; Bauer Stephen M; Killedar Smruti; Karp Matthew; Kensler Thomas W; Yamamoto Masayuki; Breysse Patrick; Biswal Shyam; Georas Steve N
Disruption of the transcription factor Nrf2 promotes pro-oxidative dendritic cells that stimulate Th2-like immunoresponsiveness upon activation by ambient particulate matter.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4545-59.
2008: Reddy N M; Kleeberger S R; Bream J H; Fallon P G; Kensler T W; Yamamoto M; Reddy S P
Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling.
Oncogene 2008;27(44):5821-32.
2008: Tong Kit I; Yamamoto Masayuki; Tanaka Toshiyuki
A simple method for amino acid selective isotope labeling of recombinant proteins in E. coli.
Journal of biomolecular NMR 2008;42(1):59-67.
2008: Yokomizo Tomomasa; Yanagida Masatoshi; Huang Gang; Osato Motomi; Honda Chikako; Ema Masatsugu; Takahashi Satoru; Yamamoto Masayuki; Ito Yoshiaki
Genetic evidence of PEBP2beta-independent activation of Runx1 in the murine embryo.
International journal of hematology 2008;88(2):134-8.
2008: Osburn William O; Yates Melinda S; Dolan Patrick D; Chen Sining; Liby Karen T; Sporn Michael B; Taguchi Keiko; Yamamoto Masayuki; Kensler Thomas W
Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice.
Toxicological sciences : an official journal of the Society of Toxicology 2008;104(1):218-27.
2008: Shi L; Itoh F; Itoh S; Takahashi S; Yamamoto M; Kato M
Ephrin-A1 promotes the malignant progression of intestinal tumors in Apc(min/+) mice.
Oncogene 2008;27(23):3265-73.
2008: Obara Naoshi; Suzuki Norio; Kim Kibom; Nagasawa Toshiro; Imagawa Shigehiko; Yamamoto Masayuki
Repression via the GATA box is essential for tissue-specific erythropoietin gene expression.
Blood 2008;111(10):5223-32.
2008: Shimizu Ritsuko; Engel James Douglas; Yamamoto Masayuki
GATA1-related leukaemias.
Nature reviews. Cancer 2008;8(4):279-87.
2008: Taguchi Keiko; Shimada Megumi; Fujii Sayako; Sumi Daigo; Pan Xiaoqing; Yamano Shigeru; Nishiyama Takahito; Hiratsuka Akira; Yamamoto Masayuki; Cho Arthur K; Froines John R; Kumagai Yoshito
Redox cycling of 9,10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells.
Free radical biology & medicine 2008;44(8):1645-55.
2008: Yokomizo Tomomasa; Hasegawa Kazuteru; Ishitobi Hiroyuki; Osato Motomi; Ema Masatsugu; Ito Yoshiaki; Yamamoto Masayuki; Takahashi Satoru
Runx1 is involved in primitive erythropoiesis in the mouse.
Blood 2008;111(8):4075-80.
2008: Brandt William; Khandekar Melin; Suzuki Norio; Yamamoto Masayuki; Lim Kim-Chew; Engel James Douglas
Defining the functional boundaries of the Gata2 locus by rescue with a linked bacterial artificial chromosome transgene.
The Journal of biological chemistry 2008;283(14):8976-83.
2008: Hoshino Tomofumi; Shimizu Ritsuko; Ohmori Shinya; Nagano Masumi; Pan Xiaoqing; Ohneda Osamu; Khandekar Melin; Yamamoto Masayuki; Lim Kim-Chew; Engel James Douglas
Reduced BMP4 abundance in Gata2 hypomorphic mutant mice result in uropathies resembling human CAKUT.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(2):159-70.
2008: Yamashita Toshiharu; Ohneda Osamu; Nagano Masumi; Iemitsu Motoyuki; Makino Yuichi; Tanaka Hirotoshi; Miyauchi Takashi; Goto Katsutoshi; Ohneda Kinuko; Fujii-Kuriyama Yoshiaki; Poellinger Lorenz; Yamamoto Masayuki
Abnormal heart development and lung remodeling in mice lacking the hypoxia-inducible factor-related basic helix-loop-helix PAS protein NEPAS.
Molecular and cellular biology 2008;28(4):1285-97.
2008: Saito Shoko; Nouno Kaoru; Shimizu Ritsuko; Yamamoto Masayuki; Nagata Kyosuke
Impairment of erythroid and megakaryocytic differentiation by a leukemia-associated and t(9;9)-derived fusion gene product, SET/TAF-Ibeta-CAN/Nup214.
Journal of cellular physiology 2008;214(2):322-33.
2008: Suzuki Takafumi; Kelly Vincent P; Motohashi Hozumi; Nakajima Osamu; Takahashi Satoru; Nishimura Susumu; Yamamoto Masayuki
Deletion of the selenocysteine tRNA gene in macrophages and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2.
The Journal of biological chemistry 2008;283(4):2021-30.
2008: Hosoya Tomonori; Harada Nobuhiko; Mimura Junsei; Motohashi Hozumi; Takahashi Satoru; Nakajima Osamu; Morita Masanobu; Kawauchi Shimako; Yamamoto Masayuki; Fujii-Kuriyama Yoshiaki
Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice.
Biochemical and biophysical research communications 2008;365(3):562-7.
2007: Jaloszynski Pawel; Murata Soichiro; Shinkai Yasuhiro; Takahashi Satoru; Kumagai Yoshito; Nishimura Susumu; Yamamoto Masayuki
Dysfunction of Nrf2 decreases KBrO3-induced oxidative DNA damage in Ogg1-null mice.
Biochemical and biophysical research communications 2007;364(4):966-71.
2007: Oshima Motohiko; Mimura Junsei; Yamamoto Masayuki; Fujii-Kuriyama Yoshiaki
Molecular mechanism of transcriptional repression of AhR repressor involving ANKRA2, HDAC4, and HDAC5.
Biochemical and biophysical research communications 2007;364(2):276-82.
2007: Papaiahgari Srinivas; Yerrapureddy Adi; Reddy Swetha R; Reddy Narsa M; Dodd-O Jeffery M; Crow Michael T; Grigoryev Dimitry N; Barnes Kathleen; Tuder Rubin M; Yamamoto Masayuki; Kensler Thomas W; Biswal Shyam; Mitzner Wayne; Hassoun Paul M; Reddy Sekhar P
Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice.
American journal of respiratory and critical care medicine 2007;176(12):1222-35.
2007: Reddy Narsa M; Kleeberger Steven R; Yamamoto Masayuki; Kensler Thomas W; Scollick Catherine; Biswal Shyam; Reddy Sekhar P
Genetic dissection of the Nrf2-dependent redox signaling-regulated transcriptional programs of cell proliferation and cytoprotection.
Physiological genomics 2007;32(1):74-81.
2007: Tanabe Osamu; Shen Yannan; Liu Qinghui; Campbell Andrew D; Kuroha Takashi; Yamamoto Masayuki; Engel James Douglas
The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription.
Genes & development 2007;21(21):2832-44.
2007: Toyama Takashi; Sumi Daigo; Shinkai Yasuhiro; Yasutake Akira; Taguchi Keiko; Tong Kit I; Yamamoto Masayuki; Kumagai Yoshito
Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.
Biochemical and biophysical research communications 2007;363(3):645-50.
2007: Kimura Momoko; Yamamoto Tae; Zhang Jianyong; Itoh Ken; Kyo Motoki; Kamiya Terue; Aburatani Hiroyuki; Katsuoka Fumiki; Kurokawa Hirofumi; Tanaka Toshiyuki; Motohashi Hozumi; Yamamoto Masayuki
Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer.
The Journal of biological chemistry 2007;282(46):33681-90.
2007: Tong Kit I; Padmanabhan Balasundaram; Kobayashi Akira; Shang Chengwei; Hirotsu Yosuke; Yokoyama Shigeyuki; Yamamoto Masayuki
Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response.
Molecular and cellular biology 2007;27(21):7511-21.
2007: Osburn William O; Karim Baktiar; Dolan Patrick M; Liu Guosheng; Yamamoto Masayuki; Huso David L; Kensler Thomas W
Increased colonic inflammatory injury and formation of aberrant crypt foci in Nrf2-deficient mice upon dextran sulfate treatment.
International journal of cancer. Journal international du cancer 2007;121(9):1883-91.
2007: Shimizu Ritsuko; Yamamoto Masayuki
[Function and gene expression regulation of GATA-1 and GATA-2 transcription]
Seikagaku. The Journal of Japanese Biochemical Society 2007;79(10):941-52.
2007: Watai Yoriko; Kobayashi Akira; Nagase Hiroko; Mizukami Mio; McEvoy Justina; Singer Jeffrey D; Itoh Ken; Yamamoto Masayuki
Subcellular localization and cytoplasmic complex status of endogenous Keap1.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(10):1163-78.
2007: Shin Soona; Wakabayashi Nobunao; Misra Vikas; Biswal Shyam; Lee Gum Hwa; Agoston Elin S; Yamamoto Masayuki; Kensler Thomas W
NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis.
Molecular and cellular biology 2007;27(20):7188-97.
2007: Wang Jian; Fields Jocelyn; Zhao Chunying; Langer John; Thimmulappa Rajesh K; Kensler Thomas W; Yamamoto Masayuki; Biswal Shyam; Doré Sylvain
Role of Nrf2 in protection against intracerebral hemorrhage injury in mice.
Free radical biology & medicine 2007;43(3):408-14.
2007: Kobayashi Makoto; Yamamoto Masayuki
Regulation of GATA1 gene expression.
Journal of biochemistry 2007;142(1):1-10.
2007: Reddy Narsa M; Kleeberger Steven R; Cho Hye-Youn; Yamamoto Masayuki; Kensler Thomas W; Biswal Shyam; Reddy Sekhar P
Deficiency in Nrf2-GSH signaling impairs type II cell growth and enhances sensitivity to oxidants.
American journal of respiratory cell and molecular biology 2007;37(1):3-8.
2007: Shah Z A; Li R-C; Thimmulappa R K; Kensler T W; Yamamoto M; Biswal S; Doré S
Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury.
Neuroscience 2007;147(1):53-9.
2007: Zhang Jianyong; Hosoya Tomonori; Maruyama Atsushi; Nishikawa Keizo; Maher Jonathan M; Ohta Tsutomu; Motohashi Hozumi; Fukamizu Akiyoshi; Shibahara Shigeki; Itoh Ken; Yamamoto Masayuki
Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.
The Biochemical journal 2007;404(3):459-66.
2007: Tanabe Osamu; McPhee David; Kobayashi Shoko; Shen Yannan; Brandt William; Jiang Xia; Campbell Andrew D; Chen Yei-Tsung; Chang Chawn shang; Yamamoto Masayuki; Tanimoto Keiji; Engel James Douglas
Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4.
The EMBO journal 2007;26(9):2295-306.
2007: Khandekar Melin; Brandt William; Zhou Yinghui; Dagenais Susan; Glover Thomas W; Suzuki Norio; Shimizu Ritsuko; Yamamoto Masayuki; Lim Kim-Chew; Engel James Douglas
A Gata2 intronic enhancer confers its pan-endothelia-specific regulation.
Development (Cambridge, England) 2007;134(9):1703-12.
2007: Shimizu Ritsuko; Trainor Cecelia D; Nishikawa Keizo; Kobayashi Makoto; Ohneda Kinuko; Yamamoto Masayuki
GATA-1 self-association controls erythroid development in vivo.
The Journal of biological chemistry 2007;282(21):15862-71.
2007: Motohashi Hozumi; Yamamoto Masayuki
Carcinogenesis and transcriptional regulation through Maf recognition elements.
Cancer science 2007;98(2):135-9.
2007: Yates Melinda S; Tauchi Masafumi; Katsuoka Fumiki; Flanders Kathleen C; Liby Karen T; Honda Tadashi; Gribble Gordon W; Johnson Delinda A; Johnson Jeffrey A; Burton Neal C; Guilarte Tomás R; Yamamoto Masayuki; Sporn Michael B; Kensler Thomas W
Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.
Molecular cancer therapeutics 2007;6(1):154-62.
2007: Yokomizo Tomomasa; Takahashi Satoru; Mochizuki Naomi; Kuroha Takashi; Ema Masatsugu; Wakamatsu Asami; Shimizu Ritsuko; Ohneda Osamu; Osato Motomi; Okada Hitoshi; Komori Toshihisa; Ogawa Minetaro; Nishikawa Shin-Ichi; Ito Yoshiaki; Yamamoto Masayuki
Characterization of GATA-1(+) hemangioblastic cells in the mouse embryo.
The EMBO journal 2007;26(1):184-96.
2006: Thimmulappa Rajesh K; Scollick Catherine; Traore Kassim; Yates Melinda; Trush Michael A; Liby Karen T; Sporn Michael B; Yamamoto Masayuki; Kensler Thomas W; Biswal Shyam
Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide.
Biochemical and biophysical research communications 2006;351(4):883-9.
2006: Sekine Hiroki; Mimura Junsei; Yamamoto Masayuki; Fujii-Kuriyama Yoshiaki
Unique and overlapping transcriptional roles of arylhydrocarbon receptor nuclear translocator (Arnt) and Arnt2 in xenobiotic and hypoxic responses.
The Journal of biological chemistry 2006;281(49):37507-16.
2006: Ema Masatsugu; Yokomizo Tomomasa; Wakamatsu Asami; Terunuma Tsumoru; Yamamoto Masayuki; Takahashi Satoru
Primitive erythropoiesis from mesodermal precursors expressing VE-cadherin, PECAM-1, Tie2, endoglin, and CD34 in the mouse embryo.
Blood 2006;108(13):4018-24.
2006: Singh Anju; Rangasamy Tirumalai; Thimmulappa Rajesh K; Lee Hannah; Osburn William O; Brigelius-Flohé Regina; Kensler Thomas W; Yamamoto Masayuki; Biswal Shyam
Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2.
American journal of respiratory cell and molecular biology 2006;35(6):639-50.
2006: Mukai Harumi Y; Motohashi Hozumi; Ohneda Osamu; Suzuki Norio; Nagano Masumi; Yamamoto Masayuki
Transgene insertion in proximity to the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation.
Molecular and cellular biology 2006;26(21):7953-65.
2006: Zhang Jianyong; Ohta Tsutomu; Maruyama Atsushi; Hosoya Tomonori; Nishikawa Keizo; Maher Jonathan M; Shibahara Shigeki; Itoh Ken; Yamamoto Masayuki
BRG1 interacts with Nrf2 to selectively mediate HO-1 induction in response to oxidative stress.
Molecular and cellular biology 2006;26(21):7942-52.
2006: Matsumoto Ken; Imagawa Shigehiko; Obara Naoshi; Suzuki Norio; Takahashi Satoru; Nagasawa Toshiro; Yamamoto Masayuki
2-Oxoglutarate downregulates expression of vascular endothelial growth factor and erythropoietin through decreasing hypoxia-inducible factor-1alpha and inhibits angiogenesis.
Journal of cellular physiology 2006;209(2):333-40.
2006: Tong Kit I; Kobayashi Akira; Katsuoka Fumiki; Yamamoto Masayuki
Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.
Biological chemistry 2006;387(10-11):1311-20.
2006: Hosoya-Ohmura Sakie; Mochizuki Naomi; Suzuki Mikiko; Ohneda Osamu; Ohneda Kinuko; Yamamoto Masayuki
GATA-4 incompletely substitutes for GATA-1 in promoting both primitive and definitive erythropoiesis in vivo.
The Journal of biological chemistry 2006;281(43):32820-30.
2006: Moriguchi Takashi; Takako Nakano; Hamada Michito; Maeda Atsuko; Fujioka Yuki; Kuroha Takashi; Huber Reuben E; Hasegawa Susan L; Rao Arvind; Yamamoto Masayuki; Takahashi Satoru; Lim Kim-Chew; Engel James Douglas
Gata3 participates in a complex transcriptional feedback network to regulate sympathoadrenal differentiation.
Development (Cambridge, England) 2006;133(19):3871-81.
2006: Yu Xiang; Egner Patricia A; Wakabayashi Junko; Wakabayashi Nobunao; Yamamoto Masayuki; Kensler Thomas W
Nrf2-mediated induction of cytoprotective enzymes by 15-deoxy-Delta12,14-prostaglandin J2 is attenuated by alkenal/one oxidoreductase.
The Journal of biological chemistry 2006;281(36):26245-52.
2006: Moriguchi Takashi; Hamada Michito; Morito Naoki; Terunuma Tsumoru; Hasegawa Kazuteru; Zhang Chuan; Yokomizo Tomomasa; Esaki Ritsuko; Kuroda Etsushi; Yoh Keigyou; Kudo Takashi; Nagata Michio; Greaves David R; Engel James Douglas; Yamamoto Masayuki; Takahashi Satoru
MafB is essential for renal development and F4/80 expression in macrophages.
Molecular and cellular biology 2006;26(15):5715-27.
2006: Suzuki Mikiko; Ohneda Kinuko; Hosoya-Ohmura Sakie; Tsukamoto Saho; Ohneda Osamu; Philipsen Sjaak; Yamamoto Masayuki
Real-time monitoring of stress erythropoiesis in vivo using Gata1 and beta-globin LCR luciferase transgenic mice.
Blood 2006;108(2):726-33.
2006: Motohashi Hozumi; Katsuoka Fumiki; Miyoshi Chika; Uchimura Yasuhiro; Saitoh Hisato; Francastel Claire; Engel James Douglas; Yamamoto Masayuki
MafG sumoylation is required for active transcriptional repression.
Molecular and cellular biology 2006;26(12):4652-63.
2006: Yamamoto Tae; Kyo Motoki; Kamiya Terue; Tanaka Toshiyuki; Engel James Douglas; Motohashi Hozumi; Yamamoto Masayuki
Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(6):575-91.
2006: Thimmulappa Rajesh K; Lee Hannah; Rangasamy Tirumalai; Reddy Sekhar P; Yamamoto Masayuki; Kensler Thomas W; Biswal Shyam
Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis.
The Journal of clinical investigation 2006;116(4):984-95.
2006: Tong Kit I; Katoh Yasutake; Kusunoki Hideki; Itoh Ken; Tanaka Toshiyuki; Yamamoto Masayuki
Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model.
Molecular and cellular biology 2006;26(8):2887-900.
2006: Satoh Kimio; Kagaya Yutaka; Nakano Makoto; Ito Yoshitaka; Ohta Jun; Tada Hiroko; Karibe Akihiko; Minegishi Naoko; Suzuki Norio; Yamamoto Masayuki; Ono Masao; Watanabe Jun; Shirato Kunio; Ishii Naoto; Sugamura Kazuo; Shimokawa Hiroaki
Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice.
Circulation 2006;113(11):1442-50.
2006: Padmanabhan Balasundaram; Tong Kit I; Ohta Tsutomu; Nakamura Yoshihiro; Scharlock Maria; Ohtsuji Makiko; Kang Moon-Il; Kobayashi Akira; Yokoyama Shigeyuki; Yamamoto Masayuki
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer.
Molecular cell 2006;21(5):689-700.
2006: Suzuki Norio; Ohneda Osamu; Minegishi Naoko; Nishikawa Mitsuo; Ohta Takayuki; Takahashi Satoru; Engel James Douglas; Yamamoto Masayuki
Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2202-7.
2006: Nagai Haruko; Kubo Masato; Abe Ryo; Yamamoto Masayuki; Nohara Keiko
Constitutive activation of the aryl hydrocarbon receptor in T-lineage cells induces thymus involution independently of the Fas/Fas ligand signaling pathway.
International immunopharmacology 2006;6(2):279-86.
2006: Fujiwara Tohru; Harigae Hideo; Takahashi Shinichiro; Furuyama Kazumichi; Nakajima Osamu; Sun Jiying; Igarashi Kazuhiko; Yamamoto Masayuki; Sassa Shigeru; Kaku Mitsuo; Sasaki Takeshi
Differential gene expression profiling between wild-type and ALAS2-null erythroblasts: identification of novel heme-regulated genes.
Biochemical and biophysical research communications 2006;340(1):105-10.
2006: Morito Naoki; Yoh Keigyou; Fujioka Yuki; Nakano Takako; Shimohata Homare; Hashimoto Yuko; Yamada Akiko; Maeda Atsuko; Matsuno Fumihiko; Hata Hiroyuki; Suzuki Atsushi; Imagawa Shigehiko; Mitsuya Hiroaki; Esumi Hiroyasu; Koyama Akio; Yamamoto Masayuki; Mori Naoyoshi; Takahashi Satoru
Overexpression of c-Maf contributes to T-cell lymphoma in both mice and human.
Cancer research 2006;66(2):812-9.
2006: Kobayashi Akira; Kang Moon-Il; Watai Yoriko; Tong Kit I; Shibata Takahiro; Uchida Koji; Yamamoto Masayuki
Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1.
Molecular and cellular biology 2006;26(1):221-9.
2006: Okawa Hiromi; Motohashi Hozumi; Kobayashi Akira; Aburatani Hiroyuki; Kensler Thomas W; Yamamoto Masayuki
Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.
Biochemical and biophysical research communications 2006;339(1):79-88.
2006: Kobayashi Makoto; Yamamoto Masayuki
Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species.
Advances in enzyme regulation 2006;46():113-40.
2005: Iizuka Takashi; Ishii Yukio; Itoh Ken; Kiwamoto Takumi; Kimura Toru; Matsuno Yosuke; Morishima Yuko; Hegab Ahmed E; Homma Shinsuke; Nomura Akihiro; Sakamoto Tohru; Shimura Masako; Yoshida Aruto; Yamamoto Masayuki; Sekizawa Kiyohisa
Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(12):1113-25.
2005: Kato Hideki; Ishida Junji; Imagawa Shigehiko; Saito Tomoko; Suzuki Norio; Matsuoka Toshiki; Sugaya Takeshi; Tanimoto Keiji; Yokoo Takashi; Ohneda Osamu; Sugiyama Fumihiro; Yagami Ken-ichi; Fujita Toshiro; Yamamoto Masayuki; Nangaku Masaomi; Fukamizu Akiyoshi
Enhanced erythropoiesis mediated by activation of the renin-angiotensin system via angiotensin II type 1a receptor.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(14):2023-5.
2005: Yanaka Akinori; Tauchi Masafumi; Yamamoto Masayuki
[Effects of sulforaphane-rich broccoli sprouts on H. pylori-infected gastric mucosa]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 11():582-6.
2005: Ishii Yukio; Itoh Ken; Morishima Yuko; Kimura Toru; Kiwamoto Takumi; Iizuka Takashi; Hegab Ahmed E; Hosoya Tomonori; Nomura Akihiro; Sakamoto Tohru; Yamamoto Masayuki; Sekizawa Kiyohisa
Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6968-75.
2005: Tauchi Masafumi; Hida Azumi; Negishi Takaaki; Katsuoka Fumiki; Noda Shuhei; Mimura Junsei; Hosoya Tomonori; Yanaka Akinori; Aburatani Hiroyuki; Fujii-Kuriyama Yoshiaki; Motohashi Hozumi; Yamamoto Masayuki
Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions.
Molecular and cellular biology 2005;25(21):9360-8.
2005: Katsuoka Fumiki; Motohashi Hozumi; Ishii Tetsuro; Aburatani Hiroyuki; Engel James Douglas; Yamamoto Masayuki
Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes.
Molecular and cellular biology 2005;25(18):8044-51.
2005: Kobayashi-Osaki Maki; Ohneda Osamu; Suzuki Norio; Minegishi Naoko; Yokomizo Tomomasa; Takahashi Satoru; Lim Kim-Chew; Engel James Douglas; Yamamoto Masayuki
GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.
Molecular and cellular biology 2005;25(16):7005-20.
2005: Rangasamy Tirumalai; Guo Jia; Mitzner Wayne A; Roman Jessica; Singh Anju; Fryer Allison D; Yamamoto Masayuki; Kensler Thomas W; Tuder Rubin M; Georas Steve N; Biswal Shyam
Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice.
The Journal of experimental medicine 2005;202(1):47-59.
2005: Minegishi Naoko; Suzuki Norio; Kawatani Yukie; Shimizu Ritsuko; Yamamoto Masayuki
Rapid turnover of GATA-2 via ubiquitin-proteasome protein degradation pathway.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(7):693-704.
2005: Hosoya Tomonori; Maruyama Atsushi; Kang Moon-Il; Kawatani Yukie; Shibata Takahiro; Uchida Koji; Warabi Eiji; Noguchi Noriko; Itoh Ken; Yamamoto Masayuki
Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells.
The Journal of biological chemistry 2005;280(29):27244-50.
2005: Zhang Chuan; Moriguchi Takashi; Kajihara Miwako; Esaki Ritsuko; Harada Ayako; Shimohata Homare; Oishi Hisashi; Hamada Michito; Morito Naoki; Hasegawa Kazuteru; Kudo Takashi; Engel James Douglas; Yamamoto Masayuki; Takahashi Satoru
MafA is a key regulator of glucose-stimulated insulin secretion.
Molecular and cellular biology 2005;25(12):4969-76.
2005: Yanagida Masatoshi; Osato Motomi; Yamashita Namiko; Liqun Huang; Jacob Bindya; Wu Feng; Cao Xinmin; Nakamura Takuro; Yokomizo Tomomasa; Takahashi Satoru; Yamamoto Masayuki; Shigesada Katsuya; Ito Yoshiaki
Increased dosage of Runx1/AML1 acts as a positive modulator of myeloid leukemogenesis in BXH2 mice.
Oncogene 2005;24(28):4477-85.
2005: Pan Xiaoqing; Ohneda Osamu; Ohneda Kinuko; Lindeboom Fokke; Iwata Fumiko; Shimizu Ritsuko; Nagano Masumi; Suwabe Naruyoshi; Philipsen Sjaak; Lim Kim-Chew; Engel James D; Yamamoto Masayuki
Graded levels of GATA-1 expression modulate survival, proliferation, and differentiation of erythroid progenitors.
The Journal of biological chemistry 2005;280(23):22385-94.
2005: Mochizuki Mie; Ishii Yukio; Itoh Ken; Iizuka Takashi; Morishima Yuko; Kimura Toru; Kiwamoto Takumi; Matsuno Yosuke; Hegab Ahamed E; Nomura Akihiro; Sakamoto Tohru; Uchida Koji; Yamamoto Masayuki; Sekizawa Kiyohisa
Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury.
American journal of respiratory and critical care medicine 2005;171(11):1260-6.
2005: Kelly Vincent P; Suzuki Takafumi; Nakajima Osamu; Arai Tsuyoshi; Tamai Yoshitaka; Takahashi Satoru; Nishimura Susumu; Yamamoto Masayuki
The distal sequence element of the selenocysteine tRNA gene is a tissue-dependent enhancer essential for mouse embryogenesis.
Molecular and cellular biology 2005;25(9):3658-69.
2005: Suzuki Takafumi; Takagi Yaeko; Osanai Hitoshi; Li Li; Takeuchi Miki; Katoh Yasutake; Kobayashi Makoto; Yamamoto Masayuki
Pi class glutathione S-transferase genes are regulated by Nrf 2 through an evolutionarily conserved regulatory element in zebrafish.
The Biochemical journal 2005;388(Pt 1):65-73.
2005: Nohara Keiko; Pan Xiaoqing; Tsukumo Shin-Ichi; Hida Azumi; Ito Tomohiro; Nagai Haruko; Inouye Kaoru; Motohashi Hozumi; Yamamoto Masayuki; Fujii-Kuriyama Yoshiaki; Tohyama Chiharu
Constitutively active aryl hydrocarbon receptor expressed specifically in T-lineage cells causes thymus involution and suppresses the immunization-induced increase in splenocytes.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(5):2770-7.
2005: Kobayashi Makoto; Yamamoto Masayuki
Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation.
Antioxidants & redox signaling 2005;7(3-4):385-94.
2005: Shimizu Ritsuko; Yamamoto Masayuki
Gene expression regulation and domain function of hematopoietic GATA factors.
Seminars in cell & developmental biology 2005;16(1):129-36.
2005: Cho Hye-Youn; Reddy Sekhar P; Debiase Andrea; Yamamoto Masayuki; Kleeberger Steven R
Gene expression profiling of NRF2-mediated protection against oxidative injury.
Free radical biology & medicine 2005;38(3):325-43.
2005: Katsuoka Fumiki; Motohashi Hozumi; Engel James Douglas; Yamamoto Masayuki
Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.
The Journal of biological chemistry 2005;280(6):4483-90.
2005: Padmanabhan Balasundaram; Scharlock Maria; Tong Kit I; Nakamura Yoshihiro; Kang Moon-Il; Kobayashi Akira; Matsumoto Takehisa; Tanaka Akiko; Yamamoto Masayuki; Yokoyama Shigeyuki
Purification, crystallization and preliminary X-ray diffraction analysis of the Kelch-like motif region of mouse Keap1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 1):153-5.
2005: Nakano Mayu; Ohneda Kinuko; Yamamoto-Mukai Harumi; Shimizu Ritsuko; Ohneda Osamu; Ohmura Sakie; Suzuki Mikiko; Tsukamoto Saho; Yanagawa Toru; Yoshida Hiroshi; Takakuwa Yuichi; Yamamoto Masayuki
Transgenic over-expression of GATA-1 mutant lacking N-finger domain causes hemolytic syndrome in mouse erythroid cells.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(1):47-62.
2005: Katoh Yasutake; Iida Katsuyuki; Kang Moon-Il; Kobayashi Akira; Mizukami Mio; Tong Kit I; McMahon Michael; Hayes John D; Itoh Ken; Yamamoto Masayuki
Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome.
Archives of biochemistry and biophysics 2005;433(2):342-50.
2005: Yanaka A; Zhang S; Tauchi M; Suzuki H; Shibahara T; Matsui H; Nakahara A; Tanaka N; Yamamoto M
Role of the nrf-2 gene in protection and repair of gastric mucosa against oxidative stress.
Inflammopharmacology 2005;13(1-3):83-90.
2005: Nishio T; Kawaguchi S; Yamamoto M; Iseda T; Kawasaki T; Hase T
Tenascin-C regulates proliferation and migration of cultured astrocytes in a scratch wound assay.
Neuroscience 2005;132(1):87-102.
2004: Shimizu Ritsuko; Kuroha Takashi; Ohneda Osamu; Pan Xiaoqing; Ohneda Kinuko; Takahashi Satoru; Philipsen Sjaak; Yamamoto Masayuki
Leukemogenesis caused by incapacitated GATA-1 function.
Molecular and cellular biology 2004;24(24):10814-25.
2004: Khandekar Melin; Suzuki Norio; Lewton Jon; Yamamoto Masayuki; Engel James Douglas
Multiple, distant Gata2 enhancers specify temporally and tissue-specific patterning in the developing urogenital system.
Molecular and cellular biology 2004;24(23):10263-76.
2004: Nakano Yoko; Imagawa Shigehiko; Matsumoto Ken; Stockmann Christian; Obara Naoshi; Suzuki Norio; Doi Takeshi; Kodama Tatsuhiko; Takahashi Satoru; Nagasawa Toshiro; Yamamoto Masayuki
Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease.
Blood 2004;104(13):4300-7.
2004: Rangasamy Tirumalai; Cho Chung Y; Thimmulappa Rajesh K; Zhen Lijie; Srisuma Sorachai S; Kensler Thomas W; Yamamoto Masayuki; Petrache Irina; Tuder Rubin M; Biswal Shyam
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice.
The Journal of clinical investigation 2004;114(9):1248-59.
2004: Motohashi Hozumi; Yamamoto Masayuki
Nrf2-Keap1 defines a physiologically important stress response mechanism.
Trends in molecular medicine 2004;10(11):549-57.
2004: Yamamoto Tae; Yoh Keigyou; Kobayashi Akira; Ishii Yukio; Kure Shigeo; Koyama Akio; Sakamoto Tohru; Sekizawa Kiyohisa; Motohashi Hozumi; Yamamoto Masayuki
Identification of polymorphisms in the promoter region of the human NRF2 gene.
Biochemical and biophysical research communications 2004;321(1):72-9.
2004: Kobayashi Akira; Kang Moon-Il; Okawa Hiromi; Ohtsuji Makiko; Zenke Yukari; Chiba Tomoki; Igarashi Kazuhiko; Yamamoto Masayuki
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
Molecular and cellular biology 2004;24(16):7130-9.
2004: Cho Hye-Youn; Reddy Sekhar P M; Yamamoto Masayuki; Kleeberger Steven R
The transcription factor NRF2 protects against pulmonary fibrosis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(11):1258-60.
2004: Yanagawa Toru; Itoh Ken; Uwayama Junya; Shibata Yasuaki; Yamaguchi Akira; Sano Tsuneyoshi; Ishii Tetsuro; Yoshida Hiroshi; Yamamoto Masayuki
Nrf2 deficiency causes tooth decolourization due to iron transport disorder in enamel organ.
Genes to cells : devoted to molecular & cellular mechanisms 2004;9(7):641-51.
2004: Takagi Yaeko; Kobayashi Makoto; Li Li; Suzuki Takafumi; Nishikawa Keizo; Yamamoto Masayuki
MafT, a new member of the small Maf protein family in zebrafish.
Biochemical and biophysical research communications 2004;320(1):62-9.
2004: Ito Tomohiro; Tsukumo Shin-Ichi; Suzuki Norio; Motohashi Hozumi; Yamamoto Masayuki; Fujii-Kuriyama Yoshiaki; Mimura Junsei; Lin Tien-Min; Peterson Richard E; Tohyama Chiharu; Nohara Keiko
A constitutively active arylhydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest.
The Journal of biological chemistry 2004;279(24):25204-10.
2004: Yoshida Shosei; Takakura Ayumi; Ohbo Kazuyuki; Abe Kuniya; Wakabayashi Junko; Yamamoto Masayuki; Suda Toshio; Nabeshima Yo-Ichi
Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis.
Developmental biology 2004;269(2):447-58.
2004: Itoh Ken; Tong Kit I; Yamamoto Masayuki
Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles.
Free radical biology & medicine 2004;36(10):1208-13.
2004: Morito Naoki; Yoh Keigyou; Hirayama Aki; Itoh Ken; Nose Masato; Koyama Akio; Yamamoto Masayuki; Takahashi Satoru
Nrf2 deficiency improves autoimmune nephritis caused by the fas mutation lpr.
Kidney international 2004;65(5):1703-13.
2004: Itoh Ken; Yamamoto Masayuki
[Molecular mechanism of adaptive response to electrophiles]
Seikagaku. The Journal of Japanese Biochemical Society 2004;76(4):339-48.
2004: Motohashi Hozumi; Katsuoka Fumiki; Engel James Douglas; Yamamoto Masayuki
Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(17):6379-84.
2004: Shimizu Ritsuko; Ohneda Kinuko; Engel James Douglas; Trainor Cecelia D; Yamamoto Masayuki
Transgenic rescue of GATA-1-deficient mice with GATA-1 lacking a FOG-1 association site phenocopies patients with X-linked thrombocytopenia.
Blood 2004;103(7):2560-7.
2004: Ishii Tetsuro; Itoh Ken; Ruiz Emilio; Leake David S; Unoki Hiroyuki; Yamamoto Masayuki; Mann Giovanni E
Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal.
Circulation research 2004;94(5):609-16.
2004: Kang Moon-Il; Kobayashi Akira; Wakabayashi Nobunao; Kim Sang-Geon; Yamamoto Masayuki
Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2046-51.
2004: Wakabayashi Nobunao; Dinkova-Kostova Albena T; Holtzclaw W David; Kang Moon-Il; Kobayashi Akira; Yamamoto Masayuki; Kensler Thomas W; Talalay Paul
Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2040-5.
2004: Imagawa S; Yamaguchi Y; Ogawa K; Obara N; Suzuki N; Yamamoto M; Nagasawa T
Interleukin-6 and tumor necrosis factor-alpha in patients with obstructive sleep apnea-hypopnea syndrome.
Respiration; international review of thoracic diseases 2004;71(1):24-9.
2004: Itoh Ken; Mochizuki Mie; Ishii Yukio; Ishii Tetsuro; Shibata Takahiro; Kawamoto Yoshiyuki; Kelly Vincent; Sekizawa Kiyohisa; Uchida Koji; Yamamoto Masayuki
Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2).
Molecular and cellular biology 2004;24(1):36-45.
2004: Kobayashi Akira; Ohta Tsutomu; Yamamoto Masayuki
Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes.
Methods in enzymology 2004;378():273-86.
2003: Morito Naoki; Yoh Keigyou; Itoh Ken; Hirayama Aki; Koyama Akio; Yamamoto Masayuki; Takahashi Satoru
Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels.
Oncogene 2003;22(58):9275-81.
2003: Obara Naoshi; Imagawa Shigehiko; Nakano Yoko; Yamamoto Masayuki; Noguchi Toshihiro; Nagasawa Toshiro
Hematological aspects of a novel 9-aminoanthracycline, amrubicin.
Cancer science 2003;94(12):1104-6.
2003: Kwak Mi-Kyoung; Wakabayashi Nobunao; Greenlaw Jennifer L; Yamamoto Masayuki; Kensler Thomas W
Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway.
Molecular and cellular biology 2003;23(23):8786-94.
2003: Nishikawa Keizo; Kobayashi Makoto; Masumi Atsuko; Lyons Susan E; Weinstein Brant M; Liu P Paul; Yamamoto Masayuki
Self-association of Gata1 enhances transcriptional activity in vivo in zebra fish embryos.
Molecular and cellular biology 2003;23(22):8295-305.
2003: Wakabayashi Nobunao; Itoh Ken; Wakabayashi Junko; Motohashi Hozumi; Noda Shuhei; Takahashi Satoru; Imakado Sumihisa; Kotsuji Tomoe; Otsuka Fujio; Roop Dennis R; Harada Takanori; Engel James Douglas; Yamamoto Masayuki
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation.
Nature genetics 2003;35(3):238-45.
2003: Suzuki Norio; Suwabe Naruyoshi; Ohneda Osamu; Obara Naoshi; Imagawa Shigehiko; Pan Xiaoqing; Motohashi Hozumi; Yamamoto Masayuki
Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels.
Blood 2003;102(10):3575-83.
2003: Yoh Keigyou; Shibuya Kazuko; Morito Naoki; Nakano Takako; Ishizaki Kazusa; Shimohata Homare; Nose Masato; Izui Shozo; Shibuya Akira; Koyama Akio; Engel James Douglas; Yamamoto Masayuki; Takahashi Satoru
Transgenic overexpression of GATA-3 in T lymphocytes improves autoimmune glomerulonephritis in mice with a BXSB/MpJ-Yaa genetic background.
Journal of the American Society of Nephrology : JASN 2003;14(10):2494-502.
2003: Imagawa Shigehiko; Nakano Yoko; Obara Naoshi; Suzuki Norio; Doi Takeshi; Kodama Tatsuhiko; Nagasawa Toshiro; Yamamoto Masayuki
A GATA-specific inhibitor (K-7174) rescues anemia induced by IL-1beta, TNF-alpha, or L-NMMA.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(12):1742-4.
2003: Minegishi Naoko; Suzuki Norio; Yokomizo Tomomasa; Pan Xiaoqing; Fujimoto Tetsuhiro; Takahashi Satoru; Hara Takahiko; Miyajima Atsushi; Nishikawa Shin-Ichi; Yamamoto Masayuki
Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos.
Blood 2003;102(3):896-905.
2003: Wakabayashi Junko; Yomogida Kentaro; Nakajima Osamu; Yoh Keigyou; Takahashi Satoru; Engel James Douglas; Ohneda Kinuko; Yamamoto Masayuki
GATA-1 testis activation region is essential for Sertoli cell-specific expression of GATA-1 gene in transgenic mouse.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(7):619-30.
2003: Aono Junko; Yanagawa Toru; Itoh Ken; Li Baojie; Yoshida Hiroshi; Kumagai Yoshito; Yamamoto Masayuki; Ishii Tetsuro
Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts.
Biochemical and biophysical research communications 2003;305(2):271-7.
2003: Obara Naoshi; Imagawa Shigehiko; Nakano Yoko; Suzuki Norio; Yamamoto Masayuki; Nagasawa Toshiro
Suppression of erythropoietin gene expression by cadmium depends on inhibition of HIF-1, not stimulation of GATA-2.
Archives of toxicology 2003;77(5):267-73.
2003: Moriguchi Takashi; Motohashi Hozumi; Hosoya Tomonori; Nakajima Osamu; Takahashi Satoru; Ohsako Seiichiroh; Aoki Yasunobu; Nishimura Noriko; Tohyama Chiharu; Fujii-Kuriyama Yoshiaki; Yamamoto Masayuki
Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5652-7.
2003: Hirayama Aki; Yoh Keigyou; Nagase Sohji; Ueda Atsushi; Itoh Ken; Morito Naoki; Hirayama Kouichi; Takahashi Satoru; Yamamoto Masayuki; Koyama Akio
EPR imaging of reducing activity in Nrf2 transcriptional factor-deficient mice.
Free radical biology & medicine 2003;34(10):1236-42.
2003: Itoh Ken; Wakabayashi Nobunao; Katoh Yasutake; Ishii Tetsuro; O'Connor Tania; Yamamoto Masayuki
Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(4):379-91.
2003: Ramos-Gomez Minerva; Dolan Patrick M; Itoh Ken; Yamamoto Masayuki; Kensler Thomas W
Interactive effects of nrf2 genotype and oltipraz on benzo[a]pyrene-DNA adducts and tumor yield in mice.
Carcinogenesis 2003;24(3):461-7.
2003: Yokoyama Hisayuki; Harigae Hideo; Takahashi Shinichiro; Takahashi Satoru; Furuyama Kazumichi; Kaku Mitsuo; Yamamoto Masayuki; Sasaki Takeshi
Regulation of YB-1 gene expression by GATA transcription factors.
Biochemical and biophysical research communications 2003;303(1):140-5.
2003: Noda Shuhei; Harada Nobuhiko; Hida Azumi; Fujii-Kuriyama Yoshiaki; Motohashi Hozumi; Yamamoto Masayuki
Gene expression of detoxifying enzymes in AhR and Nrf2 compound null mutant mouse.
Biochemical and biophysical research communications 2003;303(1):105-11.
2003: Kwak Mi-Kyoung; Wakabayashi Nobunao; Itoh Ken; Motohashi Hozumi; Yamamoto Masayuki; Kensler Thomas W
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.
The Journal of biological chemistry 2003;278(10):8135-45.
2003: Katsuoka Fumiki; Motohashi Hozumi; Tamagawa Yuna; Kure Shigeo; Igarashi Kazuhiko; Engel James Douglas; Yamamoto Masayuki
Small Maf compound mutants display central nervous system neuronal degeneration, aberrant transcription, and Bach protein mislocalization coincident with myoclonus and abnormal startle response.
Molecular and cellular biology 2003;23(4):1163-74.
2003: Harigae Hideo; Nakajima Osamu; Suwabe Naruyoshi; Yokoyama Hisayuki; Furuyama Kazumichi; Sasaki Takeshi; Kaku Mitsuo; Yamamoto Masayuki; Sassa Shigeru
Aberrant iron accumulation and oxidized status of erythroid-specific delta-aminolevulinate synthase (ALAS2)-deficient definitive erythroblasts.
Blood 2003;101(3):1188-93.
2002: Ohneda Kinuko; Shimizu Ritsuko; Nishimura Shigeko; Muraosa Yasushi; Takahashi Satoru; Engel James Douglas; Yamamoto Masayuki
A minigene containing four discrete cis elements recapitulates GATA-1 gene expression in vivo.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(12):1243-54.
2002: Ishizaki Kimitsune; Shimizu-Ueda Yuu; Okada Sachiko; Yamamoto Masayuki; Fujisawa Masaki; Yamato Katsuyuki T; Fukuzawa Hideya; Ohyama Kanji
Multicopy genes uniquely amplified in the Y chromosome-specific repeats of the liverwort Marchantia polymorpha.
Nucleic acids research 2002;30(21):4675-81.
2002: Suzuki Norio; Ohneda Osamu; Takahashi Satoru; Higuchi Masato; Mukai Harumi Y; Nakahata Tatsutoshi; Imagawa Shigehiko; Yamamoto Masayuki
Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality.
Blood 2002;100(7):2279-88.
2002: Thimmulappa Rajesh K; Mai Kim H; Srisuma Sorachai; Kensler Thomas W; Yamamoto Masayuki; Biswal Shyam
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.
Cancer research 2002;62(18):5196-203.
2002: Dinkova-Kostova Albena T; Holtzclaw W David; Cole Robert N; Itoh Ken; Wakabayashi Nobunao; Katoh Yasutake; Yamamoto Masayuki; Talalay Paul
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11908-13.
2002: Kobayashi Makoto; Itoh Ken; Suzuki Takafumi; Osanai Hitoshi; Nishikawa Keizo; Katoh Yasutake; Takagi Yaeko; Yamamoto Masayuki
Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(8):807-20.
2002: Motohashi Hozumi; O'Connor Tania; Katsuoka Fumiki; Engel James Douglas; Yamamoto Masayuki
Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors.
Gene 2002;294(1-2):1-12.
2002: Tanabe Osamu; Katsuoka Fumiki; Campbell Andrew D; Song Weimin; Yamamoto Masayuki; Tanimoto Keiji; Engel James Douglas
An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer.
The EMBO journal 2002;21(13):3434-42.
2002: Imagawa Shigehiko; Suzuki Norio; Ohmine Ken; Obara Naoshi; Mukai Harumi Y; Ozawa Keiya; Yamamoto Masayuki; Nagasawa Toshiro
GATA suppresses erythropoietin gene expression through GATA site in mouse erythropoietin gene promoter.
International journal of hematology 2002;75(4):376-81.
2002: Kwak Mi-Kyoung; Itoh Ken; Yamamoto Masayuki; Kensler Thomas W
Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter.
Molecular and cellular biology 2002;22(9):2883-92.
2002: Moriguchi Takashi; Sakurai Takeshi; Takahashi Satoru; Goto Katsutoshi; Yamamoto Masayuki
The human prepro-orexin gene regulatory region that activates gene expression in the lateral region and represses it in the medial regions of the hypothalamus.
The Journal of biological chemistry 2002;277(19):16985-92.
2002: Tun Thein; Miyoshi Hirotoshi; Aung Tun; Takahashi Satoru; Shimizu Ritsuko; Kuroha Takashi; Yamamoto Masayuki; Ohshima Norio
Effect of growth factors on ex vivo bone marrow cell expansion using three-dimensional matrix support.
Artificial organs 2002;26(4):333-9.
2002: Imagawa Shigehiko; Tarumoto Takahisa; Suzuki Norio; Mukai Harumi Y; Hasegawa Yuichi; Higuchi Masato; Neichi Tomohiro; Ozawa Keiya; Yamamoto Masayuki; Nagasawa Toshiro
L-arginine rescues decreased erythropoietin gene expression by stimulating GATA-2 with L-NMMA.
Kidney international 2002;61(2):396-404.
2002: Cho Hye-Youn; Jedlicka Anne E; Reddy Sekhar P M; Kensler Thomas W; Yamamoto Masayuki; Zhang Liu-Yi; Kleeberger Steven R
Role of NRF2 in protection against hyperoxic lung injury in mice.
American journal of respiratory cell and molecular biology 2002;26(2):175-82.
2002: Ohneda Kinuko; Yamamoto Masayuki
Roles of hematopoietic transcription factors GATA-1 and GATA-2 in the development of red blood cell lineage.
Acta haematologica 2002;108(4):237-45.
2002: Ishii Tetsuro; Itoh Ken; Yamamoto Masayuki
Roles of Nrf2 in activation of antioxidant enzyme genes via antioxidant responsive elements.
Methods in enzymology 2002;348():182-90.
2001: Fujimoto T; Ogawa M; Minegishi N; Yoshida H; Yokomizo T; Yamamoto M; Nishikawa S
Step-wise divergence of primitive and definitive haematopoietic and endothelial cell lineages during embryonic stem cell differentiation.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(12):1113-27.
2001: Yoh K; Sugawara T; Motohashi H; Takahama Y; Koyama A; Yamamoto M; Takahashi S
Transgenic over-expression of MafK suppresses T cell proliferation and function in vivo.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(12):1055-66.
2001: Katoh Y; Itoh K; Yoshida E; Miyagishi M; Fukamizu A; Yamamoto M
Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(10):857-68.
2001: Yoh K; Itoh K; Enomoto A; Hirayama A; Yamaguchi N; Kobayashi M; Morito N; Koyama A; Yamamoto M; Takahashi S
Nrf2-deficient female mice develop lupus-like autoimmune nephritis.
Kidney international 2001;60(4):1343-53.
2001: Shimizu R; Takahashi S; Ohneda K; Engel J D; Yamamoto M
In vivo requirements for GATA-1 functional domains during primitive and definitive erythropoiesis.
The EMBO journal 2001;20(18):5250-60.
2001: Kwak M K; Egner P A; Dolan P M; Ramos-Gomez M; Groopman J D; Itoh K; Yamamoto M; Kensler T W
Role of phase 2 enzyme induction in chemoprotection by dithiolethiones.
Mutation research 2001;480-481():305-15.
2001: Imagawa S; Yamaguchi Y; Higuchi M; Neichi T; Hasegawa Y; Mukai H Y; Suzuki N; Yamamoto M; Nagasawa T
Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea--hypopnea syndrome.
Blood 2001;98(4):1255-7.
2001: Kobayashi M; Nishikawa K; Yamamoto M
Hematopoietic regulatory domain of gata1 gene is positively regulated by GATA1 protein in zebrafish embryos.
Development (Cambridge, England) 2001;128(12):2341-50.
2001: Aoki Y; Sato H; Nishimura N; Takahashi S; Itoh K; Yamamoto M
Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust.
Toxicology and applied pharmacology 2001;173(3):154-60.
2001: Kim Y C; Masutani H; Yamaguchi Y; Itoh K; Yamamoto M; Yodoi J
Hemin-induced activation of the thioredoxin gene by Nrf2. A differential regulation of the antioxidant responsive element by a switch of its binding factors.
The Journal of biological chemistry 2001;276(21):18399-406.
2001: Kobayashi M; Nishikawa K; Suzuki T; Yamamoto M
The homeobox protein Six3 interacts with the Groucho corepressor and acts as a transcriptional repressor in eye and forebrain formation.
Developmental biology 2001;232(2):315-26.
2001: Ramos-Gomez M; Kwak M K; Dolan P M; Itoh K; Yamamoto M; Talalay P; Kensler T W
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3410-5.
2001: Kwak M K; Itoh K; Yamamoto M; Sutter T R; Kensler T W
Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.
Molecular medicine (Cambridge, Mass.) 2001;7(2):135-45.
2001: Tabata M; Tarumoto T; Ohmine K; Furukawa Y; Hatake K; Ozawa K; Hasegawa Y; Mukai H; Yamamoto M; Imagawa S
Stimulation of GATA-2 as a mechanism of hydrogen peroxide suppression in hypoxia-induced erythropoietin gene expression.
Journal of cellular physiology 2001;186(2):260-7.
2000: Motohashi H; Katsuoka F; Shavit J A; Engel J D; Yamamoto M
Positive or negative MARE-dependent transcriptional regulation is determined by the abundance of small Maf proteins.
Cell 2000;103(6):865-75.
2000: Kobayashi M; Osanai H; Kawakami K; Yamamoto M
Expression of three zebrafish Six4 genes in the cranial sensory placodes and the developing somites.
Mechanisms of development 2000;98(1-2):151-5.
2000: Tarumoto T; Imagawa S; Ohmine K; Nagai T; Higuchi M; Imai N; Suzuki N; Yamamoto M; Ozawa K
N(G)-monomethyl-L-arginine inhibits erythropoietin gene expression by stimulating GATA-2.
Blood 2000;96(5):1716-22.
2000: Zhou Y; Yamamoto M; Engel J D
GATA2 is required for the generation of V2 interneurons.
Development (Cambridge, England) 2000;127(17):3829-38.
2000: Yamamoto M; Nakajima O
Animal models for X-linked sideroblastic anemia.
International journal of hematology 2000;72(2):157-64.
2000: Takahashi S; Shimizu R; Suwabe N; Kuroha T; Yoh K; Ohta J; Nishimura S; Lim K C; Engel J D; Yamamoto M
GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies.
Blood 2000;96(3):910-6.
2000: Yamamoto M; Nakajima O; Furuyama K; Harigae H; Hayashi N
[Molecular diagnosis of hereditary sideroblastic anemia and model mouse of the disease]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2000;41(7):540-3.
2000: Takahashi S; Furuyama K; Kobayashi A; Taketani S; Harigae H; Yamamoto M; Igarashi K; Sasaki T; Hayashi N
Cloning of a coproporphyrinogen oxidase promoter regulatory element binding protein.
Biochemical and biophysical research communications 2000;273(2):596-602.
2000: Yamamoto M
[An approach to analyze transcription factor function in vivo utilizing specific gene regulatory regions]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(9 Suppl):1593-602.
2000: Yamamoto M
[Study of the transcription factor function in vivo: an overview]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(9 Suppl):1573-6.
2000: Katsuoka F; Motohashi H; Onodera K; Suwabe N; Engel J D; Yamamoto M
One enhancer mediates mafK transcriptional activation in both hematopoietic and cardiac muscle cells.
The EMBO journal 2000;19(12):2980-91.
2000: Ishii T; Itoh K; Takahashi S; Sato H; Yanagawa T; Katoh Y; Bannai S; Yamamoto M
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages.
The Journal of biological chemistry 2000;275(21):16023-9.
2000: Hoshino H; Kobayashi A; Yoshida M; Kudo N; Oyake T; Motohashi H; Hayashi N; Yamamoto M; Igarashi K
Oxidative stress abolishes leptomycin B-sensitive nuclear export of transcription repressor Bach2 that counteracts activation of Maf recognition element.
The Journal of biological chemistry 2000;275(20):15370-6.
2000: Takeyama O; Ikai I; Yamamoto M; Kanazawa A; Yagi T; Uesugi T; Nishitai R; Satoh S; Terajima H; Yamaoka Y
The protective role of Kupffer cells in humoral injury of xenoperfused rat livers.
Transplantation 2000;69(7):1283-9.
2000: Onodera K; Shavit J A; Motohashi H; Yamamoto M; Engel J D
Perinatal synthetic lethality and hematopoietic defects in compound mafG::mafK mutant mice.
The EMBO journal 2000;19(6):1335-45.
2000: Kobayashi A; Yamagiwa H; Hoshino H; Muto A; Sato K; Morita M; Hayashi N; Yamamoto M; Igarashi K
A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domain.
Molecular and cellular biology 2000;20(5):1733-46.
2000: Pan X; Minegishi N; Harigae H; Yamagiwa H; Minegishi M; Akine Y; Yamamoto M
Identification of human GATA-2 gene distal IS exon and its expression in hematopoietic stem cell fractions.
Journal of biochemistry 2000;127(1):105-12.
2000: Nishimura S; Takahashi S; Kuroha T; Suwabe N; Nagasawa T; Trainor C; Yamamoto M
A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene.
Molecular and cellular biology 2000;20(2):713-23.
1999: Ishikawa Y; Yamamoto Y; Kume M; Yamagami K; Yamamoto H; Kimoto S; Sakai Y; Yamamoto M; Yamaoka Y
Heat shock preconditioning on mitochondria during warm ischemia in rat livers.
The Journal of surgical research 1999;87(2):178-84.
1999: Yoshida C; Tokumasu F; Hohmura K I; Bungert J; Hayashi N; Nagasawa T; Engel J D; Yamamoto M; Takeyasu K; Igarashi K
Long range interaction of cis-DNA elements mediated by architectural transcription factor Bach1.
Genes to cells : devoted to molecular & cellular mechanisms 1999;4(11):643-55.
1999: Itoh K; Yamamoto M
[Transcriptional regulation of the phase II drug detoxifying enzyme genes]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(15 Suppl):2370-6.
1999: Yamamoto M
[Transcriptional regulation of detoxication enzyme genes: overview]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(15 Suppl):2368-9.
1999: Yamamoto M
[Present status and future aspects on study of molecular mechanisms of animal physiological adaptation to the environment]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(15 Suppl):2366-7.
1999: Nakajima O; Takahashi S; Harigae H; Furuyama K; Hayashi N; Sassa S; Yamamoto M
Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload.
The EMBO journal 1999;18(22):6282-9.
1999: Itoh K; Ishii T; Wakabayashi N; Yamamoto M
Regulatory mechanisms of cellular response to oxidative stress.
Free radical research 1999;31(4):319-24.
1999: Harigae H; Furuyama K; Kimura A; Neriishi K; Tahara N; Kondo M; Hayashi N; Yamamoto M; Sassa S; Sasaki T
A novel mutation of the erythroid-specific delta-aminolaevulinate synthase gene in a patient with X-linked sideroblastic anaemia.
British journal of haematology 1999;106(1):175-7.
1999: Onodera K; Shavit J A; Motohashi H; Katsuoka F; Akasaka J E; Engel J D; Yamamoto M
Characterization of the murine mafF gene.
The Journal of biological chemistry 1999;274(30):21162-9.
1999: Kawauchi S; Takahashi S; Nakajima O; Ogino H; Morita M; Nishizawa M; Yasuda K; Yamamoto M
Regulation of lens fiber cell differentiation by transcription factor c-Maf.
The Journal of biological chemistry 1999;274(27):19254-60.
1999: Yamamoto M; Fujinuma M; Tanaka M; Dräger U C; McCaffery P
Sagittal band expression of COUP-TF2 gene in the developing cerebellum.
Mechanisms of development 1999;84(1-2):143-6.
1999: Minegishi N; Ohta J; Yamagiwa H; Suzuki N; Kawauchi S; Zhou Y; Takahashi S; Hayashi N; Engel J D; Yamamoto M
The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region.
Blood 1999;93(12):4196-207.
1999: Kobayashi A; Ito E; Toki T; Kogame K; Takahashi S; Igarashi K; Hayashi N; Yamamoto M
Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3.
The Journal of biological chemistry 1999;274(10):6443-52.
1999: Itoh K; Wakabayashi N; Katoh Y; Ishii T; Igarashi K; Engel J D; Yamamoto M
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain.
Genes & development 1999;13(1):76-86.
1998: Kanazawa A; Tanaka A; Iwata S; Satoh S; Hatano E; Shinohara H; Kitai T; Tsunekawa S; Ikai I; Yamamoto M; Takahashi R; Chance B; Yamaoka Y
The beneficial effect of phosphocreatine accumulation in the creatine kinase transgenic mouse liver in endotoxin-induced hepatic cell death.
The Journal of surgical research 1998;80(2):229-35.
1998: Furuyama K; Uno R; Urabe A; Hayashi N; Fujita H; Kondo M; Sassa S; Yamamoto M
R411C mutation of the ALAS2 gene encodes a pyridoxine-responsive enzyme with low activity.
British journal of haematology 1998;103(3):839-41.
1998: Suwabe N; Takahashi S; Nakano T; Yamamoto M
GATA-1 regulates growth and differentiation of definitive erythroid lineage cells during in vitro ES cell differentiation.
Blood 1998;92(11):4108-18.
1998: Zhou Y; Lim K C; Onodera K; Takahashi S; Ohta J; Minegishi N; Tsai F Y; Orkin S H; Yamamoto M; Engel J D
Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital development.
The EMBO journal 1998;17(22):6689-700.
1998: Takahashi S; Taketani S; Akasaka J E; Kobayashi A; Hayashi N; Yamamoto M; Nagai T
Differential regulation of coproporphyrinogen oxidase gene between erythroid and nonerythroid cells.
Blood 1998;92(9):3436-44.
1998: Motohashi H; Ohta J; Engel J D; Yamamoto M
A core region of the mafK gene IN promoter directs neurone-specific transcription in vivo.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(10):671-84.
1998: Muto A; Hoshino H; Madisen L; Yanai N; Obinata M; Karasuyama H; Hayashi N; Nakauchi H; Yamamoto M; Groudine M; Igarashi K
Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3' enhancer.
The EMBO journal 1998;17(19):5734-43.
1998: Yamagami K; Yamamoto Y; Kume M; Kimoto S; Yamamoto H; Ozaki N; Yamamoto M; Shimahara Y; Toyokuni S; Yamaoka Y
Heat shock preconditioning ameliorates liver injury following normothermic ischemia-reperfusion in steatotic rat livers.
The Journal of surgical research 1998;79(1):47-53.
1998: Dai C L; Kume M; Yamamoto Y; Yamagami K; Yamamoto H; Nakayama H; Ozaki N; Shapiro A M; Yamamoto M; Yamaoka Y
Heat shock protein 72 production in liver tissue after experimental total hepatic inflow occlusion.
The British journal of surgery 1998;85(8):1061-5.
1998: Shavit J A; Motohashi H; Onodera K; Akasaka J; Yamamoto M; Engel J D
Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice.
Genes & development 1998;12(14):2164-74.
1998: Takahashi S; Komeno T; Suwabe N; Yoh K; Nakajima O; Nishimura S; Kuroha T; Nagasawa T; Yamamoto M
Role of GATA-1 in proliferation and differentiation of definitive erythroid and megakaryocytic cells in vivo.
Blood 1998;92(2):434-42.
1998: Igarashi K; Hoshino H; Muto A; Suwabe N; Nishikawa S; Nakauchi H; Yamamoto M
Multivalent DNA binding complex generated by small Maf and Bach1 as a possible biochemical basis for beta-globin locus control region complex.
The Journal of biological chemistry 1998;273(19):11783-90.
1998: Kuroha T; Takahashi S; Komeno T; Itoh K; Nagasawa T; Yamamoto M
Ablation of Nrf2 function does not increase the erythroid or megakaryocytic cell lineage dysfunction caused by p45 NF-E2 gene disruption.
Journal of biochemistry 1998;123(3):376-9.
1998: Nagai T; Igarashi K; Akasaka J; Furuyama K; Fujita H; Hayashi N; Yamamoto M; Sassa S
Regulation of NF-E2 activity in erythroleukemia cell differentiation.
The Journal of biological chemistry 1998;273(9):5358-65.
1998: Minegishi N; Ohta J; Suwabe N; Nakauchi H; Ishihara H; Hayashi N; Yamamoto M
Alternative promoters regulate transcription of the mouse GATA-2 gene.
The Journal of biological chemistry 1998;273(6):3625-34.
1998: Harigae H; Suwabe N; Weinstock P H; Nagai M; Fujita H; Yamamoto M; Sassa S
Deficient heme and globin synthesis in embryonic stem cells lacking the erythroid-specific delta-aminolevulinate synthase gene.
Blood 1998;91(3):798-805.
1998: Harigae H; Takahashi S; Suwabe N; Ohtsu H; Gu L; Yang Z; Tsai F Y; Kitamura Y; Engel J D; Yamamoto M
Differential roles of GATA-1 and GATA-2 in growth and differentiation of mast cells.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(1):39-50.
1997: Yagi T; Ikai I; Terajima H; Satoh S; Kanazawa A; Shinohara H; Uesugi T; Yoneyama T; Gomi T; Takahashi R; Yamamoto M; Inamoto T; Yamaoka Y
The protective effects of prostaglandin E1 on sinusoidal endothelial cells in xenogeneic pig liver perfusion.
The Journal of surgical research 1997;73(1):28-34.
1997: Yamamoto M; Sato N; Tajima H; Furuke K; Ohira A; Honda Y; Yodoi J
Induction of human thioredoxin in cultured human retinal pigment epithelial cells through cyclic AMP-dependent pathway; involvement in the cytoprotective activity of prostaglandin E1.
Experimental eye research 1997;65(5):645-52.
1997: Satoh S; Terajima H; Yagi T; Kanazawa A; Shinohara H; Gomi T; Uesugi T; Yoneyama T; Ikai I; Takahashi R; Yamamoto M; Yamaoka Y
Humoral injury in porcine livers perfused with human whole blood.
Transplantation 1997;64(8):1117-23.
1997: Motohashi H; Shavit J A; Igarashi K; Yamamoto M; Engel J D
The world according to Maf.
Nucleic acids research 1997;25(15):2953-59.
1997: Yamamoto M; Honjo T; Paumen M B
[Fatty acids-induced apoptosis]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(10 Suppl):1637-43.
1997: Itoh K; Chiba T; Takahashi S; Ishii T; Igarashi K; Katoh Y; Oyake T; Hayashi N; Satoh K; Hatayama I; Yamamoto M; Nabeshima Y
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
Biochemical and biophysical research communications 1997;236(2):313-22.
1997: Furuyama K; Fujita H; Nagai T; Yomogida K; Munakata H; Kondo M; Kimura A; Kuramoto A; Hayashi N; Yamamoto M
Pyridoxine refractory X-linked sideroblastic anemia caused by a point mutation in the erythroid 5-aminolevulinate synthase gene.
Blood 1997;90(2):822-30.
1997: Takahashi S; Onodera K; Motohashi H; Suwabe N; Hayashi N; Yanai N; Nabesima Y; Yamamoto M
Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene.
The Journal of biological chemistry 1997;272(19):12611-5.
1997: Onodera K; Takahashi S; Nishimura S; Ohta J; Motohashi H; Yomogida K; Hayashi N; Engel J D; Yamamoto M
GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4487-92.
1997: Nagai T; Harigae H; Furuyama K; Munakata H; Hayashi N; Endo K; Sassa S; Yamamoto M
5-Aminolevulinate synthase expression and hemoglobin synthesis in a human myelogenous leukemia cell line.
Journal of biochemistry 1997;121(3):487-95.
1997: Nagai M; Nagai T; Yamamoto M; Goto K; Bishop T R; Hayashi N; Kondo H; Seyama Y; Kano K; Fujita H; Sassa S
Novel regulation of delta-aminolevulinate synthase in the rat harderian gland.
Biochemical pharmacology 1997;53(5):643-50.
1997: Yamamoto M; Takahashi S; Onodera K; Muraosa Y; Engel J D
Upstream and downstream of erythroid transcription factor GATA-1.
Genes to cells : devoted to molecular & cellular mechanisms 1997;2(2):107-15.
1997: Onodera K; Yomogida K; Suwabe N; Takahashi S; Muraosa Y; Hayashi N; Ito E; Gu L; Rassoulzadegan M; Engel J D; Yamamoto M
Conserved structure, regulatory elements, and transcriptional regulation from the GATA-1 gene testis promoter.
Journal of biochemistry 1997;121(2):251-63.
1997: Terajima H; Shirakata Y; Yagi T; Mashima S; Shinohara H; Satoh S; Arima Y; Gomi T; Hirose T; Takahashi R; Ikai I; Morimoto T; Inamoto T; Yamamoto M; Yamaoka Y
Successful long-term xenoperfusion of the pig liver: continuous administration of prostaglandin E1 and insulin.
Transplantation 1997;63(4):507-12.
1997: Paumen M B; Ishida Y; Muramatsu M; Yamamoto M; Honjo T
Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis.
The Journal of biological chemistry 1997;272(6):3324-9.
1997: Yamamoto M; Ohira A; Honda O; Sato N; Furuke K; Yodoi J; Honda Y
Analysis of localization of adult T-cell leukemia-derived factor in the transient ischemic rat retina after treatment with OP-1206 alpha-CD, a prostaglandin E1 analogue.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1997;45(1):63-70.
1996: Yamamoto M; Kato K; Ikada Y
Effect of the structure of bone morphogenetic protein carriers on ectopic bone regeneration.
Tissue engineering 1996;2(4):315-26.

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