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Shinya Yamanaka

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Anatomy

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Mouse

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Tsukasa Kamakura; Jiarong Chen; Tetsuhisa Hattori; Minoru Horie; Toru Kita; Takeru Makiyama; Seiko Ohno; Kenichi Sasaki; Yimin Wuriyanghai; Shinya Yamanaka; Yoshinori Yoshida; Takeshi Kimura
Ultrastructural maturation of human-induced pluripotent stem cell-derived cardiomyocytes in a long-term culture.
Shin Kaneko; Shinya Yamanaka
To be immunogenic, or not to be: that's the iPSC question.
Keisuke Okita; Yoshiko Sato; Akira Watanabe; Tatsuya Yamakawa; Naoki Amano; Naoki Goshima; Yasuko Matsumura; Shinya Yamanaka
An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells.

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2013: Tsukasa Kamakura; Jiarong Chen; Tetsuhisa Hattori; Minoru Horie; Toru Kita; Takeru Makiyama; Seiko Ohno; Kenichi Sasaki; Yimin Wuriyanghai; Shinya Yamanaka; Yoshinori Yoshida; Takeshi Kimura
Ultrastructural maturation of human-induced pluripotent stem cell-derived cardiomyocytes in a long-term culture.
Circulation journal : official journal of the Japanese Circulation Society 2013;77(5):1307-14.
2013: Shin Kaneko; Shinya Yamanaka
To be immunogenic, or not to be: that's the iPSC question.
Cell stem cell 2013;12(4):385-6.
2013: Keisuke Okita; Yoshiko Sato; Akira Watanabe; Tatsuya Yamakawa; Naoki Amano; Naoki Goshima; Yasuko Matsumura; Shinya Yamanaka
An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells.
Stem cells (Dayton, Ohio) 2013;31(3):458-66.
2013: Akira Watanabe; Yasuhiro Yamada; Shinya Yamanaka
Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2013;368(1609):20120292.
2013: Ryota Yamana; Shinya Yamanaka; Mio Iwasaki; Masato Nakagawa; Masaki Wakabayashi; Yasushi Ishihama
Rapid and deep profiling of human induced pluripotent stem cell proteome by one-shot NanoLC-MS/MS analysis with meter-scale monolithic silica columns.
Journal of proteome research 2013;12(1):214-21.
2013: Shin-Ichi Mae; Andrew P McMahon; Naoki Nakayama; Seishi Ogawa; Takashi Aoi; Sayaka Arai; Chad A Cowan; Nanaka Gotoda-Nishimura; Masatoshi Kajiwara; Aiko Sato-Otubo; Fumihiko Shiota; Akemi Shono; Kazutoshi Takahashi; Taro Toyoda; Shinya Yamanaka; Tetsuhiko Yasuno; Kenji Osafune
Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells.
Nature communications 2013;4():1367.
2012: Yoshinori Yoshida; Shinya Yamanaka
An emerging strategy of gene therapy for cardiac disease.
Circulation research 2012;111(9):1108-10.
2012: Takayuki Tanaka; Shota Tomida; Akira Watanabe; Takuya Yamamoto; Shinya Yamanaka; Mayu Yamane; Aiko Sato-Otsubo; Kazutoshi Takahashi; Isao Asaka; Hideki Hara; Toshio Heike; John Edward Heuser; Naotomo Kambe; Masao Mitsuyama; Nobuhiro Morone; Tatsutoshi Nakahata; Saori Nakamura; Ryuta Nishikomori; Akira Niwa; Seishi Ogawa; Koichi Oshima; Megumu K Saito
Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery.
Blood 2012;120(6):1299-308.
2012: Masatoshi Kajiwara; Keisuke Okita; Ryosuke Takahashi; Naoya Takayama; Junya Toguchida; Shinji Uemoto; Takashi Aoi; Hiroshi Endo; Koji Eto; Haruhisa Inoue; Shinya Yamanaka
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(31):12538-43.
2012: Yoshinori Yoshida; Shinya Yamanaka
Labor pains of new technology: direct cardiac reprogramming.
Circulation research 2012;111(1):3-4.
2012: Shinya Yamanaka
Induced pluripotent stem cells: past, present, and future.
Cell stem cell 2012;10(6):678-84.
2012: Kenji Miki; Shigeru Miyagawa; Teruo Okano; Atsuhiro Saito; Taichi Sakaguchi; Tatsuya Shimizu; Hisazumi Uenaka; Shinya Yamanaka; Takahiro Higuchi; Yoshiki Sawa
Bioengineered myocardium derived from induced pluripotent stem cells improves cardiac function and attenuates cardiac remodeling following chronic myocardial infarction in rats.
Stem cells translational medicine 2012;1(5):430-7.
2011: Hidetoshi Sakurai; Shinya Yamanaka
[Research for cell therapy by induced pluripotent stem cell].
Nihon rinsho. Japanese journal of clinical medicine 2011;69(12):2114-8.
2011: Tomonori Nakamura; Arufumi Shiota; Tomoko Ichisaka; Masato Nakagawa; Shinya Yamanaka
Essential roles of ECAT15-2/Dppa2 in functional lung development.
Molecular and cellular biology 2011;31(21):4366-78.
2011: Keisuke Okita; Naoki Nagata; Shinya Yamanaka
Immunogenicity of induced pluripotent stem cells.
Circulation research 2011;109(7):720-1.
2011: Keisuke Okita; Shinya Yamanaka
Induced pluripotent stem cells: opportunities and challenges.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2011;366(1575):2198-207.
2011: Momoko Maekawa; Hiromi Mochizuki; Tomonori Nakamura; Ran Shibukawa; Kei Yamaguchi; Naoki Goshima; Tomoko Ichisaka; Yoshifumi Kawamura; Ikumi Kodanaka; Shinya Yamanaka
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1.
Nature 2011;474(7350):225-9.
2011: Hiroyuki Higashi; Oliver Brüstle; George Q Daley; Shinya Yamanaka
The nomenclature system should be sustainable, but also practical.
Cell stem cell 2011;8(6):606-7.
2011: Keisuke Okita; Yasuko Matsumura; Yoshiko Sato; Aki Okada; Asuka Morizane; Satoshi Okamoto; Hyenjong Hong; Masato Nakagawa; Koji Tanabe; Ken-ichi Tezuka; Toshiyuki Shibata; Takahiro Kunisada; Masayo Takahashi; Jun Takahashi; Hiroh Saji; Shinya Yamanaka
A more efficient method to generate integration-free human iPS cells.
Nature methods 2011;8(5):409-12.
2011: Shinya Yamanaka
Genome-sequencing anniversary. Of mice and humans.
Science (New York, N.Y.) 2011;331(6019):873.
2011: Yoshinori Yoshida; Shinya Yamanaka
iPS cells: a source of cardiac regeneration.
Journal of molecular and cellular cardiology 2011;50(2):327-32.
2011: Naoki Yahata; Shinya Yamanaka; Takashi Asada; Masashi Asai; Isao Asaka; Hiroyuki Hioki; Nobuhisa Iwata; Takeshi Kaneko; Shiho Kitaoka; Kei Maruyama; Tatsutoshi Nakahata; Takaomi C Saido; Kazutoshi Takahashi; Haruhisa Inoue
Anti-Aβ drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer's disease.
PloS one 2011;6(9):e25788.
2011: Hideki Uosaki; Shinya Yamanaka; Hiroyuki Fukushima; Satoshi Matsuoka; Norio Nakatsuji; Ayako Takeuchi; Jun K Yamashita
Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression.
PloS one 2011;6(8):e23657.
2011: Kumiko A Iwabuchi; Tatsuya Yamakawa; Yoshiko Sato; Tomoko Ichisaka; Kazutoshi Takahashi; Keisuke Okita; Shinya Yamanaka
ECAT11/L1td1 is enriched in ESCs and rapidly activated during iPSC generation, but it is dispensable for the maintenance and induction of pluripotency.
PloS one 2011;6(5):e20461.
2011: Masataka Fujiwara; Peishi Yan; Tomomi G Otsuji; Genta Narazaki; Hideki Uosaki; Hiroyuki Fukushima; Koichiro Kuwahara; Masaki Harada; Hiroyuki Matsuda; Satoshi Matsuoka; Keisuke Okita; Kazutoshi Takahashi; Masato Nakagawa; Tadashi Ikeda; Ryuzo Sakata; Christine L Mummery; Norio Nakatsuji; Shinya Yamanaka; Kazuwa Nakao; Jun K Yamashita
Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A.
PloS one 2011;6(2):e16734.
2010: Tatsutoshi Nakahata; Akira Niwa; Shin'ichi Takeda; Shinya Yamanaka; Tomonari Awaya; Hsi Chang; So-ichiro Fukada; Yuta Mizuno; Toshio Heike
Derivation of engraftable myogenic precursors from murine ES/iPS cells and generation of disease-specific iPS cells from patients with Duchenne muscular dystrophy (DMD) and other diseases.
Rinshō shinkeigaku = Clinical neurology 2010;50(11):889.
2010: Shinji Kaichi; Koji Hasegawa; Tomohide Takaya; Noritaka Yokoo; Takahiro Mima; Teruhisa Kawamura; Tatsuya Morimoto; Koh Ono; Shiro Baba; Hiraku Doi; Shinya Yamanaka; Tatsutoshi Nakahata; Toshio Heike
Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice.
Cardiovascular research 2010;88(2):314-23.
2010: Keisuke Okita; Shinya Yamanaka
Induction of pluripotency by defined factors.
Experimental cell research 2010;316(16):2565-70.
2010: Koichiro Homma; Masakatsu Sone; Daisuke Taura; Kenichi Yamahara; Yutaka Suzuki; Kazutoshi Takahashi; Takuhiro Sonoyama; Megumi Inuzuka; Yasutomo Fukunaga; Naohisa Tamura; Hiroshi Itoh; Shinya Yamanaka; Kazuwa Nakao
Sirt1 plays an important role in mediating greater functionality of human ES/iPS-derived vascular endothelial cells.
Atherosclerosis 2010;212(1):42-7.
2010: Masato Nakagawa; Nanako Takizawa; Megumi Narita; Tomoko Ichisaka; Shinya Yamanaka
Promotion of direct reprogramming by transformation-deficient Myc.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(32):14152-7.
2010: Yoshinori Yoshida; Shinya Yamanaka
Recent stem cell advances: induced pluripotent stem cells for disease modeling and stem cell-based regeneration.
Circulation 2010;122(1):80-7.
2010: Shinya Yamanaka
Patient-specific pluripotent stem cells become even more accessible.
Cell stem cell 2010;7(1):1-2.
2010: Yuta Mizuno; Hsi Chang; Katsutsugu Umeda; Akira Niwa; Toru Iwasa; Tomonari Awaya; So-ichiro Fukada; Hiroshi Yamamoto; Shinya Yamanaka; Tatsutoshi Nakahata; Toshio Heike
Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(7):2245-53.
2010: Shinya Yamanaka; Helen M Blau
Nuclear reprogramming to a pluripotent state by three approaches.
Nature 2010;465(7299):704-12.
2010: Keisuke Okita; Hyenjong Hong; Kazutoshi Takahashi; Shinya Yamanaka
Generation of mouse-induced pluripotent stem cells with plasmid vectors.
Nature protocols 2010;5(3):418-28.
2010: Masato Nakagawa; Shinya Yamanaka
Reprogramming of somatic cells to pluripotency.
Advances in experimental medicine and biology 2010;695():215-24.
2010: Hiroshi Egusa; Keisuke Okita; Hiroki Kayashima; Guannan Yu; Sho Fukuyasu; Makio Saeki; Takuya Matsumoto; Shinya Yamanaka; Hirofumi Yatani
Gingival fibroblasts as a promising source of induced pluripotent stem cells.
PloS one 2010;5(9):e12743.
2009: Shogo Nagata; Masashi Toyoda; Shinpei Yamaguchi; Kunio Hirano; Hatsune Makino; Koichiro Nishino; Yoshitaka Miyagawa; Hajime Okita; Nobutaka Kiyokawa; Masato Nakagawa; Shinya Yamanaka; Hidenori Akutsu; Akihiro Umezawa; Takashi Tada
Efficient reprogramming of human and mouse primary extra-embryonic cells to pluripotent stem cells.
Genes to cells : devoted to molecular & cellular mechanisms 2009;14(12):1395-404.
2009: Akira Niwa; Katsutsugu Umeda; Hsi Chang; Megumu Saito; Keisuke Okita; Kazutoshi Takahashi; Masato Nakagawa; Shinya Yamanaka; Tatsutoshi Nakahata; Toshio Heike
Orderly hematopoietic development of induced pluripotent stem cells via Flk-1(+) hemoangiogenic progenitors.
Journal of cellular physiology 2009;221(2):367-77.
2009: Noritaka Yokoo; Shiro Baba; Shinji Kaichi; Akira Niwa; Takahiro Mima; Hiraku Doi; Shinya Yamanaka; Tatsutoshi Nakahata; Toshio Heike
The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells.
Biochemical and biophysical research communications 2009;387(3):482-8.
2009: Koji Nishimura; Takayuki Nakagawa; Kazuya Ono; Hideaki Ogita; Tatsunori Sakamoto; Norio Yamamoto; Keisuke Okita; Shinya Yamanaka; Juichi Ito
Transplantation of mouse induced pluripotent stem cells into the cochlea.
Neuroreport 2009;20(14):1250-4.
2009: Yoshinori Yoshida; Kazutoshi Takahashi; Keisuke Okita; Tomoko Ichisaka; Shinya Yamanaka
Hypoxia enhances the generation of induced pluripotent stem cells.
Cell stem cell 2009;5(3):237-41.
2009: Hyenjong Hong; Kazutoshi Takahashi; Tomoko Ichisaka; Takashi Aoi; Osami Kanagawa; Masato Nakagawa; Keisuke Okita; Shinya Yamanaka
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway.
Nature 2009;460(7259):1132-5.
2009: Yasuhiko Hirami; Fumitaka Osakada; Kazutoshi Takahashi; Keisuke Okita; Shinya Yamanaka; Hanako Ikeda; Nagahisa Yoshimura; Masayo Takahashi
Generation of retinal cells from mouse and human induced pluripotent stem cells.
Neuroscience letters 2009;458(3):126-31.
2009: Daisuke Taura; Masakatsu Sone; Koichiro Homma; Naofumi Oyamada; Kazutoshi Takahashi; Naohisa Tamura; Shinya Yamanaka; Kazuwa Nakao
Induction and isolation of vascular cells from human induced pluripotent stem cells--brief report.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(7):1100-3.
2009: Mari Ohnuki; Kazutoshi Takahashi; Shinya Yamanaka
Generation and characterization of human induced pluripotent stem cells.
Current protocols in stem cell biology 2009;Chapter 4():Unit 4A.2.
2009: Noriko Tsubooka; Tomoko Ichisaka; Keisuke Okita; Kazutoshi Takahashi; Masato Nakagawa; Shinya Yamanaka
Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts.
Genes to cells : devoted to molecular & cellular mechanisms 2009;14(6):683-94.
2009: Shinya Yamanaka
A fresh look at iPS cells.
Cell 2009;137(1):13-7.
2009: Daisuke Taura; Michio Noguchi; Masakatsu Sone; Kiminori Hosoda; Eisaku Mori; Yohei Okada; Kazutoshi Takahashi; Koichiro Homma; Naofumi Oyamada; Megumi Inuzuka; Takuhiro Sonoyama; Ken Ebihara; Naohisa Tamura; Hiroshi Itoh; Hirofumi Suemori; Norio Nakatsuji; Hideyuki Okano; Shinya Yamanaka; Kazuwa Nakao
Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells.
FEBS letters 2009;583(6):1029-33.
2009: Kazutoshi Takahashi; Megumi Narita; Midori Yokura; Tomoko Ichisaka; Shinya Yamanaka
Human induced pluripotent stem cells on autologous feeders.
PloS one 2009;4(12):e8067.
2008: Keisuke Okita; Masato Nakagawa; Hong Hyenjong; Tomoko Ichisaka; Shinya Yamanaka
Generation of mouse induced pluripotent stem cells without viral vectors.
Science (New York, N.Y.) 2008;322(5903):949-53.
2008: Takashi Aoi; Kojiro Yae; Masato Nakagawa; Tomoko Ichisaka; Keisuke Okita; Kazutoshi Takahashi; Tsutomu Chiba; Shinya Yamanaka
Generation of pluripotent stem cells from adult mouse liver and stomach cells.
Science (New York, N.Y.) 2008;321(5889):699-702.
2008: Genta Narazaki; Hideki Uosaki; Mizue Teranishi; Keisuke Okita; Bongju Kim; Satoshi Matsuoka; Shinya Yamanaka; Jun K Yamashita
Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells.
Circulation 2008;118(5):498-506.
2008: Shinya Yamanaka
Pluripotency and nuclear reprogramming.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2008;363(1500):2079-87.
2008: Masato Nakagawa; Michiyo Koyanagi; Koji Tanabe; Kazutoshi Takahashi; Tomoko Ichisaka; Takashi Aoi; Keisuke Okita; Yuji Mochiduki; Nanako Takizawa; Shinya Yamanaka
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.
Nature biotechnology 2008;26(1):101-6.
2007: Kazutoshi Takahashi; Koji Tanabe; Mari Ohnuki; Megumi Narita; Tomoko Ichisaka; Kiichiro Tomoda; Shinya Yamanaka
Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Cell 2007;131(5):861-72.
2007: Atsunori Fukuhara; Morihiro Matsuda; Masako Nishizawa; Katsumori Segawa; Masaki Tanaka; Kae Kishimoto; Yasushi Matsuki; Mirei Murakami; Tomoko Ichisaka; Hiroko Murakami; Eijiro Watanabe; Toshiyuki Takagi; Megumi Akiyoshi; Tsuguteru Ohtsubo; Shinji Kihara; Shizuya Yamashita; Makoto Makishima; Tohru Funahashi; Shinya Yamanaka; Ryuji Hiramatsu; Yuji Matsuzawa; Iichiro Shimomura
Retraction.
Science (New York, N.Y.) 2007;318(5850):565.
2007: Marc Lewitzky; Shinya Yamanaka
Reprogramming somatic cells towards pluripotency by defined factors.
Current opinion in biotechnology 2007;18(5):467-73.
2007: Keisuke Okita; Tomoko Ichisaka; Shinya Yamanaka
Generation of germline-competent induced pluripotent stem cells.
Nature 2007;448(7151):313-7.
2007: Shinya Yamanaka
Strategies and new developments in the generation of patient-specific pluripotent stem cells.
Cell stem cell 2007;1(1):39-49.
2007: Kazutoshi Takahashi; Keisuke Okita; Masato Nakagawa; Shinya Yamanaka
Induction of pluripotent stem cells from fibroblast cultures.
Nature protocols 2007;2(12):3081-9.
2006: Keisuke Nimura; Chisaki Ishida; Hiroshi Koriyama; Kenichiro Hata; Shinya Yamanaka; En Li; Kiyoe Ura; Yasufumi Kaneda
Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(10):1225-37.
2006: Kazutoshi Takahashi; Shinya Yamanaka
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
Cell 2006;126(4):663-76.
2006: Keisuke Okita; Shinya Yamanaka
Intracellular signaling pathways regulating pluripotency of embryonic stem cells.
Current stem cell research & therapy 2006;1(1):103-11.
2006: Masanori Imamura; Kyoko Miura; Kumiko Iwabuchi; Tomoko Ichisaka; Masato Nakagawa; Jiyoung Lee; Mito Kanatsu-Shinohara; Takashi Shinohara; Shinya Yamanaka
Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells.
BMC developmental biology 2006;6():34.
2006: Kazutoshi Takahashi; Tomoko Ichisaka; Shinya Yamanaka
Identification of genes involved in tumor-like properties of embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2006;329():449-58.
2006: Yoshimi Tokuzawa; Masayoshi Maruyama; Shinya Yamanaka
Utilization of digital differential display to identify novel targets of Oct3/4.
Methods in molecular biology (Clifton, N.J.) 2006;329():223-31.
2006: Hisayuki Amano; Ken Itakura; Masayoshi Maruyama; Tomoko Ichisaka; Masato Nakagawa; Shinya Yamanaka
Identification and targeted disruption of the mouse gene encoding ESG1 (PH34/ECAT2/DPPA5).
BMC developmental biology 2006;6():11.
2006: Shinya Yamanaka
[Molecular mechanisms underlying pluripotency of embryonic stem cells].
Seikagaku. The Journal of Japanese Biochemical Society 2006;78(1):27-33.
2005: Kazutoshi Takahashi; M Murakami; Shinya Yamanaka
Role of the phosphoinositide 3-kinase pathway in mouse embryonic stem (ES) cells.
Biochemical Society transactions 2005;33(Pt 6):1522-5.
2005: Kazutoshi Takahashi; Masato Nakagawa; Stephen G Young; Shinya Yamanaka
Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway.
The Journal of biological chemistry 2005;280(38):32768-74.
2005: Masayoshi Maruyama; Tomoko Ichisaka; Masato Nakagawa; Shinya Yamanaka
Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells.
The Journal of biological chemistry 2005;280(26):24371-9.
2005: Kazutoshi Takahashi; Masayoshi Maruyama; Yoshimi Tokuzawa; Mirei Murakami; Yasuaki Oda; Nami Yoshikane; Kazuhiro W Makabe; Tomoko Ichisaka; Shinya Yamanaka
Evolutionarily conserved non-AUG translation initiation in NAT1/p97/DAP5 (EIF4G2).
Genomics 2005;85(3):360-71.
2005: Atsunori Fukuhara; Morihiro Matsuda; Masako Nishizawa; Katsumori Segawa; Masaki Tanaka; Kae Kishimoto; Yasushi Matsuki; Mirei Murakami; Tomoko Ichisaka; Hiroko Murakami; Eijiro Watanabe; Toshiyuki Takagi; Megumi Akiyoshi; Tsuguteru Ohtsubo; Shinji Kihara; Shizuya Yamashita; Makoto Makishima; Tohru Funahashi; Shinya Yamanaka; Ryuji Hiramatsu; Yuji Matsuzawa; Iichiro Shimomura
Visfatin: a protein secreted by visceral fat that mimics the effects of insulin.
Science (New York, N.Y.) 2005;307(5708):426-30.
2004: Mirei Murakami; Tomoko Ichisaka; Mitsuyo Maeda; Noriko Oshiro; Kenta Hara; Frank Edenhofer; Hiroshi Kiyama; Kazuyoshi Yonezawa; Shinya Yamanaka
mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells.
Molecular and cellular biology 2004;24(15):6710-8.
2003: Kaoru Mitsui; Yoshimi Tokuzawa; Hiroaki Itoh; Kohichi Segawa; Mirei Murakami; Kazutoshi Takahashi; Masayoshi Maruyama; Mitsuyo Maeda; Shinya Yamanaka
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells.
Cell 2003;113(5):631-42.
2003: Kazutoshi Takahashi; Kaoru Mitsui; Shinya Yamanaka
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells.
Nature 2003;423(6939):541-5.
2003: Yoshimi Tokuzawa; Eiko Kaiho; Masayoshi Maruyama; Kazutoshi Takahashi; Kaoru Mitsui; Mitsuyo Maeda; Hitoshi Niwa; Shinya Yamanaka
Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development.
Molecular and cellular biology 2003;23(8):2699-708.
2000: Shinya Yamanaka; X Y Zhang; M Maeda; K Miura; S Wang; R V Farese; H Iwao; T L Innerarity
Essential role of NAT1/p97/DAP5 in embryonic differentiation and the retinoic acid pathway.
The EMBO journal 2000;19(20):5533-41.