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James Brien

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Irene Zelner; David Walker; Alan Bocking; James F Brien; Richard Harding; Kelly Kenna; Gideon Koren
Meconium fatty acid ethyl esters as biomarkers of late gestational ethanol exposure and indicator of ethanol-induced multi-organ injury in fetal sheep.
Christine C Dobson; Daniel L Mongillo; Margo Poklewska-Koziell; James F Brien; Andrew Winterborn; James N Reynolds
Sensitivity of modified Biel-maze task, compared with Y-maze task, to measure spatial learning and memory deficits of ethanol teratogenicity in the guinea pig.
Amy J Hewitt; Amber L Knuff; Matthew J Jefkins; Christine P Collier; James N Reynolds; James F Brien
Chronic ethanol exposure and folic acid supplementation: fetal growth and folate status in the maternal and fetal guinea pig.

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2013: Irene Zelner; David Walker; Alan Bocking; James F Brien; Richard Harding; Kelly Kenna; Gideon Koren
Meconium fatty acid ethyl esters as biomarkers of late gestational ethanol exposure and indicator of ethanol-induced multi-organ injury in fetal sheep.
PloS one 2013;8(3):e59168.
2012: Christine C Dobson; Daniel L Mongillo; Margo Poklewska-Koziell; James F Brien; Andrew Winterborn; James N Reynolds
Sensitivity of modified Biel-maze task, compared with Y-maze task, to measure spatial learning and memory deficits of ethanol teratogenicity in the guinea pig.
Behavioural brain research 2012;233(1):162-8.
2011: Amy J Hewitt; Amber L Knuff; Matthew J Jefkins; Christine P Collier; James N Reynolds; James F Brien
Chronic ethanol exposure and folic acid supplementation: fetal growth and folate status in the maternal and fetal guinea pig.
Reproductive toxicology (Elmsford, N.Y.) 2011;31(4):500-6.
2011: Jeanne E Mulder; James F Brien; William J Racz; Takashi Takahashi; Thomas E Massey
Mechanisms of amiodarone and desethylamiodarone cytotoxicity in nontransformed human peripheral lung epithelial cells.
The Journal of pharmacology and experimental therapeutics 2011;336(2):551-9.
2010: Dragic Vukomanovic; Brian McLaughlin; Mona N Rahman; Jason Z Vlahakis; Gheorghe Roman; Ryan A Dercho; Robert T Kinobe; Maaike Hum; James F Brien; Zongchao Jia; Walter A Szarek; Kanji Nakatsu
Recombinant truncated and microsomal heme oxygenase-1 and -2: differential sensitivity to inhibitors.
Canadian journal of physiology and pharmacology 2010;88(4):480-6.
2010: Amy J Hewitt; Kevin R Walker; Susan M Kobus; Margo Poklewska-Koziell; James N Reynolds; James F Brien
Differential effects of chronic ethanol exposure on cytochrome P450 2E1 and the hypothalamic-pituitary-adrenal axis in the maternal-fetal unit of the guinea pig.
Neurotoxicology and teratology 2010;32(2):164-70.
2009: Mary C Olmstead; Amanda Martin; James F Brien; James N Reynolds
Chronic prenatal ethanol exposure increases disinhibition and perseverative responding in the adult guinea pig.
Behavioural pharmacology 2009;20(5-6):554-7.
2008: Teresa D McAdam; James F Brien; James N Reynolds; Hans C Dringenberg
Altered water-maze search behavior in adult guinea pigs following chronic prenatal ethanol exposure: lack of mitigation by postnatal fluoxetine treatment.
Behavioural brain research 2008;191(2):202-9.
2008: Adrian Nicolescu; Yanbin Ji; Jeannette L Comeau; Bruce C Hill; Takashi Takahashi; James F Brien; William J Racz; Thomas E Massey
Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells.
Toxicology and applied pharmacology 2008;227(3):370-9.
2007: Christopher M Nash; Ferda Ibram; Hans C Dringenberg; James N Reynolds; James F Brien
Effects of maternal administration of vitamins C and E on ethanol neurobehavioral teratogenicity in the guinea pig.
Alcohol (Fayetteville, N.Y.) 2007;41(8):577-86.
2007: Robert T Kinobe; Yanbin Ji; Jason Z Vlahakis; Roberto Motterlini; James F Brien; Walter A Szarek; Kanji Nakatsu
Effectiveness of novel imidazole-dioxolane heme oxygenase inhibitors in renal proximal tubule epithelial cells.
The Journal of pharmacology and experimental therapeutics 2007;323(3):763-70.
2007: Gheorghe Roman; John G Riley; Jason Z Vlahakis; Robert T Kinobe; James F Brien; Kanji Nakatsu; Walter A Szarek
Heme oxygenase inhibition by 2-oxy-substituted 1-(1H-imidazol-1-yl)-4-phenylbutanes: effect of halogen substitution in the phenyl ring.
Bioorganic & medicinal chemistry 2007;15(9):3225-34.
2007: Adrian Nicolescu; Jeannette L Comeau; Bruce C Hill; Leanne L Bedard; Takashi Takahashi; James F Brien; William J Racz; Thomas E Massey
Aryl radical involvement in amiodarone-induced pulmonary toxicity: investigation of protection by spin-trapping nitrones.
Toxicology and applied pharmacology 2007;220(1):60-71.
2006: Umar Iqbal; James F Brien; A Kapoor; Stephen G Matthews; James N Reynolds
Chronic prenatal ethanol exposure increases glucocorticoid-induced glutamate release in the hippocampus of the near-term foetal guinea pig.
Journal of neuroendocrinology 2006;18(11):826-34.
2006: Robert T Kinobe; Ryan A Dercho; Jason Z Vlahakis; James F Brien; Walter A Szarek; Kanji Nakatsu
Inhibition of the enzymatic activity of heme oxygenases by azole-based antifungal drugs.
The Journal of pharmacology and experimental therapeutics 2006;319(1):277-84.
2006: Robert T Kinobe; Jason Z Vlahakis; Jonathan M Soong; Walter A Szarek; James F Brien; Lawrence D Longo; Kanji Nakatsu
Heme oxygenase activity in fetal and adult sheep is not altered by acclimatization to high altitude hypoxia.
Canadian journal of physiology and pharmacology 2006;84(8-9):893-901.
2006: Jason Z Vlahakis; Robert T Kinobe; Raymond J Bowers; James F Brien; Kanji Nakatsu; Walter A Szarek
Imidazole-dioxolane compounds as isozyme-selective heme oxygenase inhibitors.
Journal of medicinal chemistry 2006;49(14):4437-41.
2006: James F Brien; Daphne Chan; Courtney R Green; Umar Iqbal; Joey Gareri; Susan M Kobus; Brian E McLaughlin; Julia Klein; Chitra Rao; James N Reynolds; Alan D Bocking; Gideon Koren
Chronic prenatal ethanol exposure and increased concentration of fatty acid ethyl esters in meconium of term fetal Guinea pig.
Therapeutic drug monitoring 2006;28(3):345-50.
2006: Umar Iqbal; Shivani Rikhy; Hans C Dringenberg; James F Brien; James N Reynolds
Spatial learning deficits induced by chronic prenatal ethanol exposure can be overcome by non-spatial pre-training.
Neurotoxicology and teratology 2006;28(3):333-41.
2006: Robert T Kinobe; Jason Z Vlahakis; Hendrik J Vreman; David K Stevenson; James F Brien; Walter A Szarek; Kanji Nakatsu
Selectivity of imidazole-dioxolane compounds for in vitro inhibition of microsomal haem oxygenase isoforms.
British journal of pharmacology 2006;147(3):307-15.
2006: Courtney R Green; Lora Talley Watts; Susan M Kobus; George I Henderson; James N Reynolds; James F Brien
Effects of chronic prenatal ethanol exposure on mitochondrial glutathione and 8-iso-prostaglandin F2alpha concentrations in the hippocampus of the perinatal guinea pig.
Reproduction, fertility, and development 2006;18(5):517-24.
2005: Daniela L Caprara; James F Brien; Umar Iqbal; James N Reynolds; Julia Klein; Gideon Koren
A Guinea pig model for the identification of in utero alcohol exposure using fatty acid ethyl esters in neonatal hair.
Pediatric research 2005;58(6):1158-63.
2005: Courtney R Green; Susan M Kobus; Y Ji; Brian M Bennett; James N Reynolds; James F Brien
Chronic prenatal ethanol exposure increases apoptosis in the hippocampus of the term fetal guinea pig.
Neurotoxicology and teratology 2005;27(6):871-81.
2005: H Ahmed; Brian E McLaughlin; Jonathan M Soong; Gerald S Marks; James F Brien; Kanji Nakatsu
The source of endogenous carbon monoxide formation in human placental chorionic villi.
Cellular and molecular biology (Noisy-le-Grand, France) 2005;51(5):447-51.
2005: Umar Iqbal; James F Brien; Sonja Banjanin; Marcus H Andrews; Stephen G Matthews; James N Reynolds
Chronic prenatal ethanol exposure alters glucocorticoid signalling in the hippocampus of the postnatal Guinea pig.
Journal of neuroendocrinology 2005;17(9):600-8.
2005: Jason Z Vlahakis; Robert T Kinobe; Raymond J Bowers; James F Brien; Kanji Nakatsu; Walter A Szarek
Synthesis and evaluation of azalanstat analogues as heme oxygenase inhibitors.
Bioorganic & medicinal chemistry letters 2005;15(5):1457-61.
2004: Michelle L Byrnes; DP Richardson; James F Brien; James N Reynolds; Hans C Dringenberg
Spatial acquisition in the Morris water maze and hippocampal long-term potentiation in the adult guinea pig following brain growth spurt--prenatal ethanol exposure.
Neurotoxicology and teratology 2004;26(4):543-51.
2004: Umar Iqbal; Hans C Dringenberg; James F Brien; James N Reynolds
Chronic prenatal ethanol exposure alters hippocampal GABA(A) receptors and impairs spatial learning in the guinea pig.
Behavioural brain research 2004;150(1-2):117-25.
2004: Kinga Jaronczyk; Loc Bui; Jonathan M Soong; Brian E McLaughlin; Gerald S Marks; James F Brien; Kanji Nakatsu
The source of heme for vascular heme oxygenase II: de novo heme biosynthesis in rat aorta.
Canadian journal of physiology and pharmacology 2004;82(4):218-24.
2004: Loc Bui; Kimberly Rish; Kinga Jaronczyk; Stephane Bourque; Brian E McLaughlin; James F Brien; Gerald S Marks; Ann Smith; Kanji Nakatsu
The source of heme for vascular heme oxygenase I: heme uptake in rat aorta.
Canadian journal of physiology and pharmacology 2004;82(4):209-17.
2004: M L Hayward; A E Martin; James F Brien; Hans C Dringenberg; Mary C Olmstead; James N Reynolds
Chronic prenatal ethanol exposure impairs conditioned responding and enhances GABA release in the hippocampus of the adult guinea pig.
The Journal of pharmacology and experimental therapeutics 2004;308(2):644-50.
2004: Craig D C Bailey; James F Brien; James N Reynolds
Chronic prenatal ethanol exposure alters the proportion of GABAergic neurons in layers II/III of the adult guinea pig somatosensory cortex.
Neurotoxicology and teratology 2004;26(1):59-63.
2003: Scott D Appleton; Gendie Lash; Gerald S Marks; Kanji Nakatsu; James F Brien; Graeme N Smith; Charles H Graham
Effect of glucose and oxygen deprivation on heme oxygenase expression in human chorionic villi explants and immortalized trophoblast cells.
American journal of physiology. Regulatory, integrative and comparative physiology 2003;285(6):R1453-60.
2003: Jeffrey W Card; William J Racz; James F Brien; Solomon B Margolin; Thomas E Massey
Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity.
Toxicological sciences : an official journal of the Society of Toxicology 2003;75(1):169-80.
2003: Tara N McGoey; James N Reynolds; James F Brien
Chronic prenatal ethanol exposure-induced decrease of guinea pig hippocampal CA1 pyramidal cell and cerebellar Purkinje cell density.
Canadian journal of physiology and pharmacology 2003;81(5):476-84.
2003: Michelle L Byrnes; James N Reynolds; James F Brien
Brain growth spurt-prenatal ethanol exposure and the guinea pig hippocampal glutamate signaling system.
Neurotoxicology and teratology 2003;25(3):303-10.
2003: Brian E McLaughlin; Gendie Lash; Graeme N Smith; Gerald S Marks; Kanji Nakatsu; Charles H Graham; James F Brien
Heme oxygenase expression in selected regions of term human placenta.
Experimental biology and medicine (Maywood, N.J.) 2003;228(5):564-7.
2003: Todd S Dettmer; Alicia Barnes; Umar Iqbal; Craig D C Bailey; James N Reynolds; James F Brien; C Fernando Valenzuela
Chronic prenatal ethanol exposure alters ionotropic glutamate receptor subunit protein levels in the adult guinea pig cerebral cortex.
Alcoholism, clinical and experimental research 2003;27(4):677-81.
2003: Scott D Appleton; Gerald S Marks; Kanji Nakatsu; James F Brien; Graeme N Smith; Charles H Graham; Gendie Lash
Effects of hypoxia on heme oxygenase expression in human chorionic villi explants and immortalized trophoblast cells.
American journal of physiology. Heart and circulatory physiology 2003;284(3):H853-8.
2003: Marjie Hard; Umar Iqbal; James F Brien; Gideon Koren
Binding of acetaldehyde to human and Guinea pig placentae in vitro.
Placenta 2003;24(2-3):149-54.
2003: Rajan K Puri; James N Reynolds; James F Brien
Effects of chronic prenatal ethanol exposure on NMDA receptor number and affinity for [3H]MK-801 in the cerebral cortex of the young postnatal and adult guinea-pig.
Reproduction, fertility, and development 2003;15(4):207-14.
2003: NS Butters; James N Reynolds; James F Brien
Effects of chronic prenatal ethanol exposure on cGMP content and glutamate release in the hippocampus of the neonatal guinea pig.
Neurotoxicology and teratology 2003;25(1):59-68.
2003: Jeffrey W Card; William J Racz; James F Brien; Thomas E Massey
Attenuation of amiodarone-induced pulmonary fibrosis by vitamin E is associated with suppression of transforming growth factor-beta1 gene expression but not prevention of mitochondrial dysfunction.
The Journal of pharmacology and experimental therapeutics 2003;304(1):277-83.
2003: Gendie Lash; Brian E McLaughlin; Shannyn K Macdonald-Goodfellow; Graeme N Smith; James F Brien; Gerald S Marks; Kanji Nakatsu; Charles H Graham
Relationship between tissue damage and heme oxygenase expression in chorionic villi of term human placenta.
American journal of physiology. Heart and circulatory physiology 2003;284(1):H160-7.
2002: DP Richardson; Michelle L Byrnes; James F Brien; James N Reynolds; Hans C Dringenberg
Impaired acquisition in the water maze and hippocampal long-term potentiation after chronic prenatal ethanol exposure in the guinea-pig.
The European journal of neuroscience 2002;16(8):1593-8.
2002: Shannon A Bainbridge; Anne E Farley; Brian E McLaughlin; Charles H Graham; Gerald S Marks; Kanji Nakatsu; James F Brien; Graeme N Smith
Carbon monoxide decreases perfusion pressure in isolated human placenta.
Placenta 2002;23(8-9):563-9.
2002: S Hosein; Gerald S Marks; James F Brien; Brian E McLaughlin; Kanji Nakatsu
An extracellular source of heme can induce a significant heme oxygenase mediated relaxation in the rat aorta.
Canadian journal of physiology and pharmacology 2002;80(8):761-5.
2002: Scott D Appleton; Gerald S Marks; Kanji Nakatsu; James F Brien; Graeme N Smith; Charles H Graham
Heme oxygenase activity in placenta: direct dependence on oxygen availability.
American journal of physiology. Heart and circulatory physiology 2002;282(6):H2055-9.
2002: Gerald S Marks; Hendrik J Vreman; Brian E McLaughlin; James F Brien; Kanji Nakatsu
Measurement of endogenous carbon monoxide formation in biological systems.
Antioxidants & redox signaling 2002;4(2):271-7.
2001: Brian E McLaughlin; Gendie Lash; Charles H Graham; Graeme N Smith; Hendrik J Vreman; David K Stevenson; Gerald S Marks; Kanji Nakatsu; James F Brien
Endogenous carbon monoxide formation by chorionic villi of term human placenta.
Placenta 2001;22(10):886-8.
2001: W H Chung; Brian M Bennett; William J Racz; James F Brien; Thomas E Massey
Induction of c-jun and TGF-beta 1 in Fischer 344 rats during amiodarone-induced pulmonary fibrosis.
American journal of physiology. Lung cellular and molecular physiology 2001;281(5):L1180-8.
2001: Hans C Dringenberg; DP Richardson; James F Brien; James N Reynolds
Spatial learning in the guinea pig: cued versus non-cued learning, sex differences, and comparison with rats.
Behavioural brain research 2001;124(1):97-101.
2001: MW Bolt; William J Racz; James F Brien; Thomas E Massey
Effects of vitamin E on cytotoxicity of amiodarone and N-desethylamiodarone in isolated hamster lung cells.
Toxicology 2001;166(3):109-18.
2001: MW Bolt; Jeffrey W Card; William J Racz; James F Brien; Thomas E Massey
Disruption of mitochondrial function and cellular ATP levels by amiodarone and N-desethylamiodarone in initiation of amiodarone-induced pulmonary cytotoxicity.
The Journal of pharmacology and experimental therapeutics 2001;298(3):1280-9.
2001: NS Butters; James N Reynolds; James F Brien
In vitro ethanol exposure decreases potassium-stimulated, but not veratridine-stimulated, glutamate release in the guinea pig hippocampus.
Alcohol (Fayetteville, N.Y.) 2001;25(1):49-53.
2001: Michelle L Byrnes; James N Reynolds; James F Brien
Effect of prenatal ethanol exposure during the brain growth spurt of the guinea pig.
Neurotoxicology and teratology 2001;23(4):355-64.
2001: Craig D C Bailey; James F Brien; James N Reynolds
Chronic prenatal ethanol exposure increases GABA(A) receptor subunit protein expression in the adult guinea pig cerebral cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(12):4381-9.
2001: D A O'Reilly; Brian E McLaughlin; Gerald S Marks; James F Brien; Kanji Nakatsu
YC-1 enhances the responsiveness of tolerant vascular smooth muscle to glyceryl trinitrate.
Canadian journal of physiology and pharmacology 2001;79(1):43-8.
2000: Brian E McLaughlin; J M Hutchinson; Charles H Graham; Graeme N Smith; Gerald S Marks; Kanji Nakatsu; James F Brien
Heme oxygenase activity in term human placenta.
Placenta 2000;21(8):870-3.
2000: KA Kimura; James N Reynolds; James F Brien
Ethanol neurobehavioral teratogenesis and the role of the hippocampal glutamate-N-methyl-D-aspartate receptor-nitric oxide synthase system.
Neurotoxicology and teratology 2000;22(5):607-16.
2000: NS Butters; M A Gibson; James N Reynolds; James F Brien
Effects of chronic prenatal ethanol exposure on hippocampal glutamate release in the postnatal guinea pig.
Alcohol (Fayetteville, N.Y.) 2000;21(1):1-9.
2000: Brian E McLaughlin; M L Chretien; C Choi; James F Brien; Kanji Nakatsu; Gerald S Marks
Potentiation of carbon monoxide-induced relaxation of rat aorta by YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole].
Canadian journal of physiology and pharmacology 2000;78(4):343-9.
2000: M A Gibson; NS Butters; James N Reynolds; James F Brien
Effects of chronic prenatal ethanol exposure on locomotor activity, and hippocampal weight, neurons, and nitric oxide synthase activity of the young postnatal guinea pig.
Neurotoxicology and teratology 2000;22(2):183-92.
2000: A C Crowe; M E Chang; Brian E McLaughlin; James F Brien
Nitric oxide formation from glyceryl trinitrate in the developing guinea-pig hippocampus.
Reproduction, fertility, and development 2000;12(5-6):245-9.
1999: Craig D C Bailey; James F Brien; James N Reynolds
Altered GABA(A)-benzodiazepine receptor number and pharmacology in the adult guinea pig cerebral cortex after chronic prenatal ethanol exposure.
Alcoholism, clinical and experimental research 1999;23(11):1816-24.
1999: Scott D Appleton; M L Chretien; Brian E McLaughlin; Hendrik J Vreman; David K Stevenson; James F Brien; Kanji Nakatsu; Donald H Maurice; Gerald S Marks
Selective inhibition of heme oxygenase, without inhibition of nitric oxide synthase or soluble guanylyl cyclase, by metalloporphyrins at low concentrations.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(10):1214-9.
1999: KA Kimura; James N Reynolds; James F Brien
Ontogeny of nitric oxide synthase I and III protein expression and enzymatic activity in the guinea pig hippocampus.
Brain research. Developmental brain research 1999;116(2):211-6.
1999: KA Kimura; J Chiu; James N Reynolds; James F Brien
Effect of chronic prenatal ethanol exposure on nitric oxide synthase I and III proteins in the hippocampus of the near-term fetal guinea pig.
Neurotoxicology and teratology 1999;21(3):251-9.
1999: AS Hussain; N H Crispino; Brian E McLaughlin; James F Brien; Gerald S Marks; Kanji Nakatsu
Glyceryl trinitrate-induced vasodilation is inhibited by ultraviolet irradiation despite enhanced nitric oxide generation: evidence for formation of a nitric oxide conjugate.
The Journal of pharmacology and experimental therapeutics 1999;289(2):895-900.
1999: Jeffrey W Card; R G Leeder; William J Racz; James F Brien; TM Bray; Thomas E Massey
Effects of dietary vitamin E supplementation on pulmonary morphology and collagen deposition in amiodarone- and vehicle-treated hamsters.
Toxicology 1999;133(2-3):75-84.
1999: J Chiu; James F Brien; P Wu; J H Eubanks; L Zhang; James N Reynolds
Chronic ethanol exposure alters MK-801 binding sites in the cerebral cortex of the near-term fetal guinea pig.
Alcohol (Fayetteville, N.Y.) 1999;17(3):215-21.
1999: Craig D C Bailey; James F Brien; James N Reynolds
Neurosteroid modulation of the GABAA receptor in the developing guinea pig cerebral cortex.
Brain research. Developmental brain research 1999;113(1-2):21-8.
1998: M J Odrcich; Charles H Graham; K A Kimura; Brian E McLaughlin; Gerald S Marks; Kanji Nakatsu; James F Brien
Heme oxygenase and nitric oxide synthase in the placenta of the guinea-pig during gestation.
Placenta 1998;19(7):509-16.
1998: Jeffrey W Card; B R Lalonde; Elizabeth Rafeiro; Andrew S Tam; William J Racz; James F Brien; TM Bray; Thomas E Massey
Amiodarone-induced disruption of hamster lung and liver mitochondrial function: lack of association with thiobarbituric acid-reactive substance production.
Toxicology letters 1998;98(1-2):41-50.
1998: G N Smith; James F Brien
Use of nitroglycerin for uterine relaxation.
Obstetrical & gynecological survey 1998;53(9):559-65.
1998: MW Bolt; William J Racz; James F Brien; TM Bray; Thomas E Massey
Differential susceptibilities of isolated hamster lung cell types to amiodarone toxicity.
Canadian journal of physiology and pharmacology 1998;76(7-8):721-7.
1998: D V Vukomanovic; A Hussain; Dick E Zoutman; Gerald S Marks; James F Brien; Kanji Nakatsu
Analysis of nanomolar S-nitrosothiol concentrations in physiological media.
Journal of pharmacological and toxicological methods 1998;39(4):235-40.
1998: M F Kearney; James F Brien; Gerald S Marks; H Lei; Kanji Nakatsu
Thiol agents separate nitric oxide formation from vasodilation induced by glyceryl trinitrate.
Drug metabolism and disposition: the biological fate of chemicals 1998;26(6):547-51.
1998: KA Kimura; James F Brien
Hippocampal nitric oxide synthase in the fetal guinea pig: effects of chronic prenatal ethanol exposure.
Brain research. Developmental brain research 1998;106(1-2):39-46.
1997: AS Hussain; Gerald S Marks; James F Brien; Kanji Nakatsu
The soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3-alpha]quinoxalin-1-one (ODQ) inhibits relaxation of rabbit aortic rings induced by carbon monoxide, nitric oxide, and glyceryl trinitrate.
Canadian journal of physiology and pharmacology 1997;75(8):1034-7.
1997: M N Cook; Gerald S Marks; Hendrik J Vreman; Brian E McLaughlin; Kanji Nakatsu; David K Stevenson; James F Brien
Carbon monoxide formation in the guinea pig hippocampus: ontogeny and effect of in vitro ethanol exposure.
Brain research. Developmental brain research 1997;101(1-2):283-6.
1997: AS Hussain; T N Abu-Zahra; James F Brien; Gerald S Marks; Kanji Nakatsu
Thiol agents potentiate glyceryl trinitrate mediated relaxation of rabbit taenia coli: evidence for thiol-dependent biotransformation.
Canadian journal of physiology and pharmacology 1997;75(7):807-11.
1997: Gerald S Marks; Brian E McLaughlin; Hendrik J Vreman; David K Stevenson; Kanji Nakatsu; James F Brien; Stephen C Pang
Heme oxygenase activity and immunohistochemical localization in bovine pulmonary artery and vein.
Journal of cardiovascular pharmacology 1997;30(1):1-6.
1997: AS Hussain; J Bozinovski; Donald H Maurice; Brian E McLaughlin; Gerald S Marks; James F Brien; Kanji Nakatsu
Inhibition of the action of nitric oxide prodrugs by pyocyanin: mechanistic studies.
Canadian journal of physiology and pharmacology 1997;75(5):398-406.
1997: M N Cook; Gerald S Marks; Hendrik J Vreman; Kanji Nakatsu; David K Stevenson; James F Brien
Heme oxygenase activity and acute and chronic ethanol exposure in the hippocampus, frontal cerebral cortex, and cerebellum of the near-term fetal guinea pig.
Alcohol (Fayetteville, N.Y.) 1997;14(2):117-24.
1997: D V Vukomanovic; Dick E Zoutman; J A Stone; Gerald S Marks; James F Brien; Kanji Nakatsu
Electrospray mass-spectrometric, spectrophotometric and electrochemical methods do not provide evidence for the binding of nitric oxide by pyocyanine at pH 7.
The Biochemical journal 1997;322 ( Pt 1)():25-9.
1996: D V Vukomanovic; Dick E Zoutman; Gerald S Marks; James F Brien; G W van Loon; Kanji Nakatsu
Analysis of pyocyanin from Pseudomonas aeruginosa by adsorptive stripping voltammetry.
Journal of pharmacological and toxicological methods 1996;36(2):97-102.
1996: Carole S Watson; Susan E White; Jacobus H Homan; S Abdollah; James F Brien; John R G Challis; Alan D Bocking
Fetal breathing is not inhibited by ethanol exposure during prolonged reduced uterine blood flow.
Canadian journal of physiology and pharmacology 1996;74(9):1016-24.
1996: KA Kimura; A M Parr; James F Brien
Effect of chronic maternal ethanol administration on nitric oxide synthase activity in the hippocampus of the mature fetal guinea pig.
Alcoholism, clinical and experimental research 1996;20(5):948-53.
1996: AS Hussain; James F Brien; Gerald S Marks; Kanji Nakatsu
Superoxide does not inhibit glyceryl trinitrate-rabbit aortic strip-mediated relaxation of rabbit Taenia coli. Evidence against a role for nitric oxide itself as the smooth muscle active drug metabolite?
Drug metabolism and disposition: the biological fate of chemicals 1996;24(7):780-5.
1996: M N Cook; Gerald S Marks; Hendrik J Vreman; Kanji Nakatsu; David K Stevenson; James F Brien
Ontogeny of heme oxygenase activity in the hippocampus, frontal cerebral cortex, and cerebellum of the guinea pig.
Brain research. Developmental brain research 1996;92(1):18-23.
1996: R G Leeder; E Rafeiro; James F Brien; C C Mandin; Thomas E Massey
Evaluation of reactive oxygen species involvement in amiodarone pulmonary toxicity in vivo and in vitro.
Journal of biochemical toxicology 1996;11(3):147-60.
1996: James F Brien; Brian E McLaughlin; Kanji Nakatsu; Gerald S Marks
Chemiluminescence headspace-gas analysis for determination of nitric oxide formation in biological systems.
Methods in enzymology 1996;268():83-92.
1995: Thomas E Massey; R G Leeder; E Rafeiro; James F Brien
Mechanisms in the pathogenesis of amiodarone-induced pulmonary toxicity.
Canadian journal of physiology and pharmacology 1995;73(12):1675-85.
1995: Gerald S Marks; Brian E McLaughlin; S L Jimmo; M Poklewska-Koziell; James F Brien; Kanji Nakatsu
Time-dependent increase in nitric oxide formation concurrent with vasodilation induced by sodium nitroprusside, 3-morpholinosydnonimine, and S-nitroso-N-acetylpenicillamine but not by glyceryl trinitrate.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(11):1248-52.
1995: J D Reynolds; James F Brien
Ethanol neurobehavioural teratogenesis and the role of L-glutamate in the fetal hippocampus.
Canadian journal of physiology and pharmacology 1995;73(9):1209-23.
1995: Z G Liu; Brian E McLaughlin; Gerald S Marks; James F Brien; Kanji Nakatsu
Sulfhydryl involvement in nitric oxide sequestration and nitric oxide induced guanylyl cyclase activation in vascular smooth muscle.
Canadian journal of physiology and pharmacology 1995;73(8):1144-8.
1995: H S Bobier; G N Smith; S R Pancham; James F Brien
Comparative study of sodium nitroprusside induced vasodilation of human placental veins from premature and full-term normotensive and preeclamptic pregnancy.
Canadian journal of physiology and pharmacology 1995;73(8):1118-22.
1995: S Abdollah; James F Brien
Effect of chronic maternal ethanol administration on glutamate and N-methyl-D-aspartate binding sites in the hippocampus of the near-term fetal guinea pig.
Alcohol (Fayetteville, N.Y.) 1995;12(4):377-82.
1995: S Abdollah; James F Brien
Glutamate and N-methyl-D-aspartate binding sites in the guinea pig hippocampus: ontogeny and effect of acute in vitro ethanol exposure.
Alcohol (Fayetteville, N.Y.) 1995;12(4):369-75.
1995: James F Brien; J D Reynolds; M A Cunningham; A M Parr; S Waddock; B E Kalisch
Nitric oxide synthase activity in the hippocampus, frontal cerebral cortex, and cerebellum of the guinea pig: ontogeny and in vitro ethanol exposure.
Alcohol (Fayetteville, N.Y.) 1995;12(4):329-33.
1995: M N Cook; Kanji Nakatsu; Gerald S Marks; Brian E McLaughlin; Hendrik J Vreman; David K Stevenson; James F Brien
Heme oxygenase activity in the adult rat aorta and liver as measured by carbon monoxide formation.
Canadian journal of physiology and pharmacology 1995;73(4):515-8.
1995: J D Reynolds; James F Brien
The role of adenosine A1 receptor activation in ethanol-induced inhibition of stimulated glutamate release in the hippocampus of the fetal and adult guinea pig.
Alcohol (Fayetteville, N.Y.) 1995;12(2):151-7.
1995: M C Catlin; Donald Penning; James F Brien
Effect of exposure in vitro to ethanol and hypoxia on gamma-aminobutyric acid efflux in the hippocampus of the fetal and adult guinea-pig.
Reproduction, fertility, and development 1995;7(5):1339-44.
1994: AS Hussain; M Poklewska-Koziell; James F Brien; Gerald S Marks; Kanji Nakatsu
Nitric oxide formation from glyceryl trinitrate by rabbit aortic strip: detection by rabbit taenia coli concurrent with vasorelaxation.
British journal of pharmacology 1994;113(4):1508-14.
1994: R G Leeder; C D Evans; James F Brien; Thomas E Massey
Resistance of the hamster to amiodarone-induced pulmonary toxicity following repeated intraperitoneal administration.
Toxicology letters 1994;74(1):51-9.
1994: E Rafeiro; R G Leeder; James F Brien; G W Kabalka; N Chatla; Thomas E Massey
Comparison of the in vivo pulmonary toxicity of amiodarone and des-oxo-amiodarone in the hamster.
Toxicology and applied pharmacology 1994;127(2):275-81.
1994: J Bozinovski; James F Brien; Gerald S Marks; Kanji Nakatsu
Inhibition of nitrovasodilators by pyocyanin and methylene blue is dissociated from nitric oxide formation.
Canadian journal of physiology and pharmacology 1994;72(7):746-52.
1994: R G Leeder; James F Brien; Thomas E Massey
Investigation of the role of oxidative stress in amiodarone-induced pulmonary toxicity in the hamster.
Canadian journal of physiology and pharmacology 1994;72(6):613-21.
1994: B P Booth; James F Brien; Gerald S Marks; Brian Milne; F Cervenko; J Pym; J Knight; K Rogers; Tomas A Salerno; Kanji Nakatsu
The effects of hypothermic and normothermic cardiopulmonary bypass on glyceryl trinitrate activity.
Anesthesia and analgesia 1994;78(5):848-56.
1994: J D Reynolds; James F Brien
Effects of acute ethanol exposure on glutamate release in the hippocampus of the fetal and adult guinea pig.
Alcohol (Fayetteville, N.Y.) 1994;11(3):259-67.
1994: Alan D Bocking; L J Carmichael; S Abdollah; K R Sinervo; G N Smith; James F Brien
Effect of ethanol on immature ovine fetal breathing movements, fetal prostaglandin E2, and myometrial activity.
The American journal of physiology 1994;266(4 Pt 2):R1297-301.
1993: E D Beaton; Z Liu; Brian E McLaughlin; James F Brien; Kanji Nakatsu; Gerald S Marks
A novel method for detection of nitric oxide binding sites by using a chemiluminescence-headspace gas technique.
Journal of pharmacological and toxicological methods 1993;30(4):217-22.
1993: Z Liu; Kanji Nakatsu; James F Brien; E D Beaton; Gerald S Marks; Donald H Maurice
Selective sequestration of nitric oxide by subcellular components of vascular smooth muscle and platelets: relationship to nitric oxide stimulation of the soluble guanylyl cyclase.
Canadian journal of physiology and pharmacology 1993;71(12):938-45.
1993: S Abdollah; M C Catlin; James F Brien
Ethanol neuro-behavioural teratogenesis in the guinea pig: behavioural dysfunction and hippocampal morphologic change.
Canadian journal of physiology and pharmacology 1993;71(10-11):776-82.
1993: Gerald S Marks; Kanji Nakatsu; James F Brien
Does endogenous zinc protoporphyrin modulate carbon monoxide formation from heme? Implications for long-term potentiation, memory, and cognitive function.
Canadian journal of physiology and pharmacology 1993;71(10-11):753-4.
1993: Alan D Bocking; K R Sinervo; G N Smith; Lesley Carmichael; John R G Challis; David M Olson; James F Brien
Increased uteroplacental production of prostaglandin E2 during ethanol infusion.
The American journal of physiology 1993;265(3 Pt 2):R640-5.
1993: B P Booth; James F Brien; Gerald S Marks; Kanji Nakatsu
Effect of temperature on glyceryl trinitrate induced relaxation of rabbit aorta.
Canadian journal of physiology and pharmacology 1993;71(8):629-32.
1993: Z Liu; James F Brien; Gerald S Marks; Brian E McLaughlin; Kanji Nakatsu
Lack of evidence for the involvement of cytochrome P-450 or other hemoproteins in metabolic activation of glyceryl trinitrate in rabbit aorta.
The Journal of pharmacology and experimental therapeutics 1993;264(3):1432-9.
1993: M C Catlin; S Abdollah; James F Brien
Dose-dependent effects of prenatal ethanol exposure in the guinea pig.
Alcohol (Fayetteville, N.Y.) 1993;10(2):109-15.
1992: J D Reynolds; James F Brien
Ontogeny of glutamate and gamma-aminobutyric acid release in the hippocampus of the guinea pig.
Journal of developmental physiology 1992;18(5):243-52.
1992: Kanji Nakatsu; James F Brien; G Savard; Edwin B Toffelmire; Hoshiar Abdollah; Brian M Bennett; Gerald S Marks
Plasma disposition and hemodynamic effects of a single oral dose of isosorbide dinitrate in human males and females.
Biopharmaceutics & drug disposition 1992;13(5):357-67.
1992: K R Sinervo; G N Smith; Alan D Bocking; J Patrick; James F Brien
Effect of ethanol on the release of prostaglandins from ovine fetal brain stem during gestation.
Alcoholism, clinical and experimental research 1992;16(3):443-8.
1992: Gerald S Marks; Brian E McLaughlin; Kanji Nakatsu; James F Brien
Biotransformation of glyceryl trinitrate by rat brain homogenate.
Canadian journal of physiology and pharmacology 1992;70(6):935-7.
1992: Gerald S Marks; Brian E McLaughlin; Kanji Nakatsu; James F Brien
Direct evidence for nitric oxide formation from glyceryl trinitrate during incubation with intact bovine pulmonary artery.
Canadian journal of physiology and pharmacology 1992;70(2):308-11.
1992: Z Liu; James F Brien; Gerald S Marks; Brian E McLaughlin; Kanji Nakatsu
Carbon monoxide does not inhibit glyceryl trinitrate biotransformation by or relaxation of aorta.
European journal of pharmacology 1992;211(1):129-32.
1991: Donald Penning; J Patrick; S Jimmo; James F Brien
Release of glutamate and gamma-aminobutyric acid in the ovine fetal hippocampus: ontogeny and effect of hypoxia.
Journal of developmental physiology 1991;16(5):301-7.
1991: G N Smith; K R Sinervo; Lesley Carmichael; J Patrick; Alan D Bocking; James F Brien
The effects of indomethacin and prostaglandin E2 on the ethanol-induced suppression of ovine fetal breathing movements.
Journal of developmental physiology 1991;16(4):239-42.
1991: Gerald S Marks; Brian E McLaughlin; L B Brown; D E Beaton; B P Booth; Kanji Nakatsu; James F Brien
Interaction of glyceryl trinitrate and sodium nitroprusside with bovine pulmonary vein homogenate and 10,000 x g supernatant: biotransformation and nitric oxide formation.
Canadian journal of physiology and pharmacology 1991;69(6):889-92.
1991: Hoshiar Abdollah; F J Brennan; S Jimmo; James F Brien
Relationship between myocardial amiodarone concentration and antiarrhythmic effect in dogs with myocardial infarction and electrically induced ventricular arrhythmias.
Canadian journal of physiology and pharmacology 1991;69(6):812-7.
1991: Kanji Nakatsu; J Pym; S Witte; Gerald S Marks; James F Brien
Adrenoceptors of the human internal thoracic artery.
Canadian journal of physiology and pharmacology 1991;69(6):792-7.
1991: G N Smith; J Patrick; K R Sinervo; James F Brien
Effects of ethanol exposure on the embryo-fetus: experimental considerations, mechanisms, and the role of prostaglandins.
Canadian journal of physiology and pharmacology 1991;69(5):550-69.
1991: Gerald S Marks; James F Brien; Kanji Nakatsu; Brian E McLaughlin
Does carbon monoxide have a physiological function?
Trends in pharmacological sciences 1991;12(5):185-8.
1991: F J Brennan; James F Brien; P W Armstrong
Plasma concentration time course and pharmacological effects of a standardized oral amiodarone dosing regimen in humans.
The Canadian journal of cardiology 1991;7(3):117-24.
1991: B P Booth; M Henderson; Brian Milne; F Cervenko; Gerald S Marks; James F Brien; Kanji Nakatsu
Sequestration of glyceryl trinitrate (nitroglycerin) by cardiopulmonary bypass oxygenators.
Anesthesia and analgesia 1991;72(4):493-7.
1991: D Treissman; James F Brien
Fetal guinea pig brain 15-hydroxyprostaglandin dehydrogenase: ontogeny and effect of ethanol.
Alcohol (Fayetteville, N.Y.) 1991;8(2):97-102.
1991: James F Brien; Brian E McLaughlin; Kanji Nakatsu; Gerald S Marks
Quantitation of nitric oxide formation from nitrovasodilator drugs by chemiluminescence analysis of headspace gas.
Journal of pharmacological methods 1991;25(1):19-27.
1991: D Treissman; G N Smith; J Patrick; James F Brien
Effect of ethanol on 15-hydroxyprostaglandin dehydrogenase activity in the brain stem of the near-term fetal sheep.
Developmental pharmacology and therapeutics 1991;16(1):48-52.
1991: James F Brien; G N Smith
Effects of alcohol (ethanol) on the fetus.
Journal of developmental physiology 1991;15(1):21-32.
1990: B P Booth; Brian M Bennett; James F Brien; D A Elliott; Gerald S Marks; J L McCans; Kanji Nakatsu
Assay of glyceryl trinitrate, isosorbide dinitrate, and their metabolites in plasma by large-bore capillary column gas-liquid chromatography.
Biopharmaceutics & drug disposition 1990;11(8):663-77.
1990: James F Brien; S Jimmo; F J Brennan; P W Armstrong; Hoshiar Abdollah
Disposition of amiodarone and its proximate metabolite, desethylamiodarone, in the dog for oral administration of single-dose and short-term drug regimens.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(6):846-51.
1990: J M Daniels; R G Leeder; James F Brien; Thomas E Massey
Repeated amiodarone exposure in the rat: toxicity and effects on hepatic and extrahepatic monooxygenase activities.
Canadian journal of physiology and pharmacology 1990;68(9):1261-8.
1990: G N Smith; James F Brien; Jacobus H Homan; Lesley Carmichael; D Treissman; J Patrick
Effect of ethanol on ovine fetal and maternal plasma prostaglandin E2 concentrations and fetal breathing movements.
Journal of developmental physiology 1990;14(1):23-8.
1990: G N Smith; James F Brien; Jacobus H Homan; Lesley Carmichael; J Patrick
Indomethacin reversal of ethanol-induced suppression of ovine fetal breathing movements and relationship to prostaglandin E2.
Journal of developmental physiology 1990;14(1):29-35.
1990: E Rafeiro; R G Leeder; J M Daniels; James F Brien; Thomas E Massey
In vitro hepatic, renal, and pulmonary N-dealkylation of amiodarone.
Biochemical pharmacology 1990;39(10):1627-9.
1990: Donald Penning; J Patrick; James F Brien
Effects of hypoxia on release of amino acid neurotransmitters from fetal lamb brain in vitro.
Canadian journal of anaesthesia = Journal canadien d'anesthésie 1990;37(4 Pt 2):S2.
1990: Hoshiar Abdollah; James F Brien; F J Brennan
Antiarrhythmic effect of chronic oral amiodarone treatment in dogs with myocardial infarction and reproducibly inducible sustained ventricular arrhythmias.
Journal of cardiovascular pharmacology 1990;15(5):799-807.
1990: J H Kawamoto; Brian E McLaughlin; James F Brien; Gerald S Marks; Kanji Nakatsu
Biotransformation of glyceryl trinitrate and elevation of cyclic GMP precede glyceryl trinitrate-induced vasodilation.
Journal of cardiovascular pharmacology 1990;15(5):714-9.
1989: C J Slack; Brian E McLaughlin; James F Brien; Gerald S Marks; Kanji Nakatsu
Biotransformation of glyceryl trinitrate and isosorbide dinitrate in vascular smooth muscle made tolerant to organic nitrates.
Canadian journal of physiology and pharmacology 1989;67(11):1381-5.
1989: J M Daniels; James F Brien; Thomas E Massey
Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone.
Toxicology and applied pharmacology 1989;100(2):350-9.
1989: S E Card; S F Tompkins; James F Brien
Ontogeny of the activity of alcohol dehydrogenase and aldehyde dehydrogenases in the liver and placenta of the guinea pig.
Biochemical pharmacology 1989;38(15):2535-41.
1989: G N Smith; James F Brien; Jacobus H Homan; Lesley Carmichael; J Patrick
Indomethacin antagonizes the ethanol-induced suppression of breathing activity but not the suppression of brain activity in the near-term fetal sheep.
Journal of developmental physiology 1989;12(2):69-75.
1989: S E Card; James F Brien
No effect of chronic ethanol administration on the activity of alcohol dehydrogenase and aldehyde dehydrogenases in the near-term pregnant guinea pig.
Canadian journal of physiology and pharmacology 1989;67(6):601-6.
1989: G N Smith; James F Brien; Lesley Carmichael; D W Clarke; J Patrick
Effect of acute, multiple-dose ethanol on maternal and fetal blood gases and acid-base balance in the near-term pregnant ewe.
Canadian journal of physiology and pharmacology 1989;67(6):686-8.
1989: Gerald S Marks; Brian E McLaughlin; H F MacMillan; Kanji Nakatsu; James F Brien
Differential biotransformation of glyceryl trinitrate by red blood cell-supernatant fraction and pulmonary vein homogenate.
Canadian journal of physiology and pharmacology 1989;67(5):417-22.
1989: G N Smith; James F Brien; Lesley Carmichael; Jacobus H Homan; D W Clarke; J Patrick
Development of tolerance to ethanol-induced suppression of breathing movements and brain activity in the near-term fetal sheep during short-term maternal administration of ethanol.
Journal of developmental physiology 1989;11(3):189-97.
1989: D W Clarke; G N Smith; J Patrick; B Richardson; James F Brien
Activity of alcohol dehydrogenase and aldehyde dehydrogenase in maternal liver, fetal liver and placenta of the near-term pregnant ewe.
Developmental pharmacology and therapeutics 1989;12(1):35-41.
1989: Gerald S Marks; Kanji Nakatsu; B McLaughlin; J Kawamoto; C Slack; James F Brien
The role of nitric oxide formation in organic nitrate-induced vasodilation and organic nitrate tolerance.
Zeitschrift für Kardiologie 1989;78 Suppl 2():18-21; discussion 64-7.
1989: Hoshiar Abdollah; James F Brien; F J Brennan
Antiarrhythmic effects of desethylamiodarone in dogs with subacute myocardial infarction and inducible ventricular arrhythmias.
Journal of cardiovascular pharmacology 1989;13(1):37-44.
1988: C J Slack; Brian E McLaughlin; Kanji Nakatsu; Gerald S Marks; James F Brien
Nitric oxide-induced vasodilation of organic nitrate-tolerant rabbit aorta.
Canadian journal of physiology and pharmacology 1988;66(10):1344-6.
1988: D W Clark; G N Smith; J Patrick; B Richardson; James F Brien
Disposition of ethanol and its proximate metabolite, acetaldehyde, in the near-term pregnant ewe for short term maternal administration of moderate-dose ethanol.
Drug metabolism and disposition: the biological fate of chemicals 1988;16(3):464-8.
1988: Kanji Nakatsu; J H Kawamoto; James F Brien; Gerald S Marks
A facile, reliable method for staining blood vessel endothelium.
Journal of pharmacological methods 1988;19(2):149-54.
1988: G S Tam; H MacMillan; Brian M Bennett; Gerald S Marks; James F Brien; Kanji Nakatsu
Patterns of isosorbide dinitrate and glyceryl trinitrate metabolites formed by selected segments of the rabbit gastrointestinal tract.
Canadian journal of physiology and pharmacology 1988;66(2):166-70.
1988: J H Kawamoto; James F Brien; Gerald S Marks; Kanji Nakatsu
Mechanism of glyceryl trinitrate-induced vasodilation. II. Lack of evidence for specific binding of GTN to bovine pulmonary vein.
The Journal of pharmacology and experimental therapeutics 1988;244(1):328-34.
1988: James F Brien; Brian E McLaughlin; Susan M Kobus; J H Kawamoto; Kanji Nakatsu; Gerald S Marks
Mechanism of glyceryl trinitrate-induced vasodilation. I. Relationship between drug biotransformation, tissue cyclic GMP elevation and relaxation of rabbit aorta.
The Journal of pharmacology and experimental therapeutics 1988;244(1):322-7.
1987: G S Tam; Gerald S Marks; James F Brien; Kanji Nakatsu
Sex- and species-related differences in the biotransformation of isosorbide dinitrate by various tissues of the rabbit and rat.
Canadian journal of physiology and pharmacology 1987;65(7):1478-83.
1987: J H Kawamoto; James F Brien; Gerald S Marks; Kanji Nakatsu
A comparative study of glyceryl trinitrate biotransformation and glyceryl trinitrate induced relaxation in bovine pulmonary artery and vein.
Canadian journal of physiology and pharmacology 1987;65(6):1146-50.
1987: James F Brien; S Jimmo; F J Brennan; SE Ford; P W Armstrong
Distribution of amiodarone and its metabolite, desethylamiodarone, in human tissues.
Canadian journal of physiology and pharmacology 1987;65(3):360-4.
1987: G S Tam; Kanji Nakatsu; James F Brien; Gerald S Marks
Determination of isosorbide dinitrate biotransformation in various tissues of the rabbit by capillary column gas-liquid chromatography.
Biopharmaceutics & drug disposition 1987;8(1):37-45.
1986: Kanji Nakatsu; M Vandenberghe; Susan M Kobus; J Kawamoto; James F Brien; Gerald S Marks
Endothelium-dependent relaxation of rabbit aorta by acetylcholine requires ethylenediaminetetraacetic acid.
Canadian journal of physiology and pharmacology 1986;64(7):1050-2.
1986: B M Bennett; Susan M Kobus; James F Brien; Kanji Nakatsu; Gerald S Marks
Requirement for reduced, unliganded hemoprotein for the hemoglobin- and myoglobin-mediated biotransformation of glyceryl trinitrate.
The Journal of pharmacology and experimental therapeutics 1986;237(2):629-35.
1984: Brian M Bennett; G S Tam; K Van Alstyne; James F Brien; Kanji Nakatsu; Gerald S Marks
Effect of 5-isosorbide mononitrate on isosorbide dinitrate-induced relaxation of rabbit aortic rings.
Canadian journal of physiology and pharmacology 1984;62(9):1194-7.