Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

James Brien

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Physiology

Living Beings

Anatomy

Disorders

Concepts & Ideas

Body Weight

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
74
Nakatsu, Kanji
67
Marks, Gerald
37
McLaughlin, Brian
32
Reynolds, James
18
Massey, Thomas
10
Racz, William
9
Vreman, Hendrik
9
Graham, Charles
8
Dringenberg, Hans
8
Iqbal, Umar
8
Smith, Graeme
8
Stevenson, David
7
Szarek, Walter
7
Vlahakis, Jason
7
Kinobe, Robert

Sign-in to see all Coauthors

Publications

TOP 3
Olmstead Mary C; Martin Amanda; Brien James F; Reynolds James N
Chronic prenatal ethanol exposure increases disinhibition and perseverative responding in the adult guinea pig.
McAdam Teresa D; Brien James F; Reynolds James N; Dringenberg Hans C
Altered water-maze search behavior in adult guinea pigs following chronic prenatal ethanol exposure: lack of mitigation by postnatal fluoxetine treatment.
Nicolescu Adrian C; Ji Yanbin; Comeau Jeannette L; Hill Bruce C; Takahashi Takashi; Brien James F; Racz William J; Massey Thomas E
Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of James Brien (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Olmstead Mary C; Martin Amanda; Brien James F; Reynolds James N
Chronic prenatal ethanol exposure increases disinhibition and perseverative responding in the adult guinea pig.
Behavioural pharmacology 2009;20(5-6):554-7.
2008: McAdam Teresa D; Brien James F; Reynolds James N; Dringenberg Hans C
Altered water-maze search behavior in adult guinea pigs following chronic prenatal ethanol exposure: lack of mitigation by postnatal fluoxetine treatment.
Behavioural brain research 2008;191(2):202-9.
2008: Nicolescu Adrian C; Ji Yanbin; Comeau Jeannette L; Hill Bruce C; Takahashi Takashi; Brien James F; Racz William J; Massey Thomas E
Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells.
Toxicology and applied pharmacology 2008;227(3):370-9.
2007: Nash Christopher M; Ibram Ferda; Dringenberg Hans C; Reynolds James N; Brien James F
Effects of maternal administration of vitamins C and E on ethanol neurobehavioral teratogenicity in the guinea pig.
Alcohol (Fayetteville, N.Y.) 2007;41(8):577-86.
2007: Kinobe Robert T; Ji Yanbin; Vlahakis Jason Z; Motterlini Roberto; Brien James F; Szarek Walter A; Nakatsu Kanji
Effectiveness of novel imidazole-dioxolane heme oxygenase inhibitors in renal proximal tubule epithelial cells.
The Journal of pharmacology and experimental therapeutics 2007;323(3):763-70.
2007: Roman Gheorghe; Riley John G; Vlahakis Jason Z; Kinobe Robert T; Brien James F; Nakatsu Kanji; Szarek Walter A
Heme oxygenase inhibition by 2-oxy-substituted 1-(1H-imidazol-1-yl)-4-phenylbutanes: effect of halogen substitution in the phenyl ring.
Bioorganic & medicinal chemistry 2007;15(9):3225-34.
2007: Nicolescu Adrian C; Comeau Jeannette L; Hill Bruce C; Bedard Leanne L; Takahashi Takashi; Brien James F; Racz William J; Massey Thomas E
Aryl radical involvement in amiodarone-induced pulmonary toxicity: investigation of protection by spin-trapping nitrones.
Toxicology and applied pharmacology 2007;220(1):60-71.
2006: Iqbal U; Brien J F; Kapoor A; Matthews S G; Reynolds J N
Chronic prenatal ethanol exposure increases glucocorticoid-induced glutamate release in the hippocampus of the near-term foetal guinea pig.
Journal of neuroendocrinology 2006;18(11):826-34.
2006: Kinobe Robert T; Dercho Ryan A; Vlahakis Jason Z; Brien James F; Szarek Walter A; Nakatsu Kanji
Inhibition of the enzymatic activity of heme oxygenases by azole-based antifungal drugs.
The Journal of pharmacology and experimental therapeutics 2006;319(1):277-84.
2006: Kinobe Robert T; Vlahakis Jason Z; Soong Jonathan M; Szarek Walter A; Brien James F; Longo Lawrence D; Nakatsu Kanji
Heme oxygenase activity in fetal and adult sheep is not altered by acclimatization to high altitude hypoxia.
Canadian journal of physiology and pharmacology 2006;84(8-9):893-901.
2006: Vlahakis Jason Z; Kinobe Robert T; Bowers Raymond J; Brien James F; Nakatsu Kanji; Szarek Walter A
Imidazole-dioxolane compounds as isozyme-selective heme oxygenase inhibitors.
Journal of medicinal chemistry 2006;49(14):4437-41.
2006: Brien James F; Chan Daphne; Green Courtney R; Iqbal Umar; Gareri Joey; Kobus Susan M; McLaughlin Brian E; Klein Julia; Rao Chitra; Reynolds James N; Bocking Alan D; Koren Gideon
Chronic prenatal ethanol exposure and increased concentration of fatty acid ethyl esters in meconium of term fetal Guinea pig.
Therapeutic drug monitoring 2006;28(3):345-50.
2006: Iqbal Umar; Rikhy Shivani; Dringenberg Hans C; Brien James F; Reynolds James N
Spatial learning deficits induced by chronic prenatal ethanol exposure can be overcome by non-spatial pre-training.
Neurotoxicology and teratology 2006;28(3):333-41.
2006: Kinobe Robert T; Vlahakis Jason Z; Vreman Hendrik J; Stevenson David K; Brien James F; Szarek Walter A; Nakatsu Kanji
Selectivity of imidazole-dioxolane compounds for in vitro inhibition of microsomal haem oxygenase isoforms.
British journal of pharmacology 2006;147(3):307-15.
2006: Green C R; Watts L T; Kobus S M; Henderson G I; Reynolds J N; Brien J F
Effects of chronic prenatal ethanol exposure on mitochondrial glutathione and 8-iso-prostaglandin F2alpha concentrations in the hippocampus of the perinatal guinea pig.
Reproduction, fertility, and development 2006;18(5):517-24.
2005: Caprara Daniela L; Brien James F; Iqbal Umar; Reynolds James N; Klein Julia; Koren Gideon
A Guinea pig model for the identification of in utero alcohol exposure using fatty acid ethyl esters in neonatal hair.
Pediatric research 2005;58(6):1158-63.
2005: Green C R; Kobus S M; Ji Y; Bennett B M; Reynolds J N; Brien J F
Chronic prenatal ethanol exposure increases apoptosis in the hippocampus of the term fetal guinea pig.
Neurotoxicology and teratology 2005;27(6):871-81.
2005: Ahmed H; McLaughlin B E; Soong J; Marks G S; Brien J F; Nakatsu K
The source of endogenous carbon monoxide formation in human placental chorionic villi.
Cellular and molecular biology (Noisy-le-Grand, France) 2005;51(5):447-51.
2005: Iqbal U; Brien J F; Banjanin S; Andrews M H; Matthews S G; Reynolds J N
Chronic prenatal ethanol exposure alters glucocorticoid signalling in the hippocampus of the postnatal Guinea pig.
Journal of neuroendocrinology 2005;17(9):600-8.
2005: Vlahakis Jason Z; Kinobe Robert T; Bowers Raymond J; Brien James F; Nakatsu Kanji; Szarek Walter A
Synthesis and evaluation of azalanstat analogues as heme oxygenase inhibitors.
Bioorganic & medicinal chemistry letters 2005;15(5):1457-61.
2004: Byrnes M L; Richardson D P; Brien J F; Reynolds J N; Dringenberg H C
Spatial acquisition in the Morris water maze and hippocampal long-term potentiation in the adult guinea pig following brain growth spurt--prenatal ethanol exposure.
Neurotoxicology and teratology 2004;26(4):543-51.
2004: Jaronczyk Kinga; Bui Loc; Soong Jonathan M; McLaughlin Brian E; Marks Gerald S; Brien James F; Nakatsu Kanji
The source of heme for vascular heme oxygenase II: de novo heme biosynthesis in rat aorta.
Canadian journal of physiology and pharmacology 2004;82(4):218-24.
2004: Bui Loc; Rish Kimberly; Jaronczyk Kinga; Bourque Stephane; McLaughlin Brian E; Brien James F; Marks Gerald S; Smith Ann; Nakatsu Kanji
The source of heme for vascular heme oxygenase I: heme uptake in rat aorta.
Canadian journal of physiology and pharmacology 2004;82(4):209-17.
2004: Iqbal U; Dringenberg H C; Brien J F; Reynolds J N
Chronic prenatal ethanol exposure alters hippocampal GABA(A) receptors and impairs spatial learning in the guinea pig.
Behavioural brain research 2004;150(1-2):117-25.
2004: Hayward M L; Martin A E; Brien J F; Dringenberg H C; Olmstead M C; Reynolds J N
Chronic prenatal ethanol exposure impairs conditioned responding and enhances GABA release in the hippocampus of the adult guinea pig.
The Journal of pharmacology and experimental therapeutics 2004;308(2):644-50.
2004: Bailey Craig D C; Brien James F; Reynolds James N
Chronic prenatal ethanol exposure alters the proportion of GABAergic neurons in layers II/III of the adult guinea pig somatosensory cortex.
Neurotoxicology and teratology 2004;26(1):59-63.
2003: Appleton S D; Lash G E; Marks G S; Nakatsu K; Brien J F; Smith G N; Graham C H
Effect of glucose and oxygen deprivation on heme oxygenase expression in human chorionic villi explants and immortalized trophoblast cells.
American journal of physiology. Regulatory, integrative and comparative physiology 2003;285(6):R1453-60.
2003: Card Jeffrey W; Racz William J; Brien James F; Margolin Solomon B; Massey Thomas E
Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity.
Toxicological sciences : an official journal of the Society of Toxicology 2003;75(1):169-80.
2003: McGoey Tara N; Reynolds James N; Brien James F
Chronic prenatal ethanol exposure-induced decrease of guinea pig hippocampal CA1 pyramidal cell and cerebellar Purkinje cell density.
Canadian journal of physiology and pharmacology 2003;81(5):476-84.
2003: Byrnes Michelle L; Reynolds James N; Brien James F
Brain growth spurt-prenatal ethanol exposure and the guinea pig hippocampal glutamate signaling system.
Neurotoxicology and teratology 2003;25(3):303-10.
2003: McLaughlin Brian E; Lash Gendie E; Smith Graeme N; Marks Gerald S; Nakatsu Kanji; Graham Charles H; Brien James F
Heme oxygenase expression in selected regions of term human placenta.
Experimental biology and medicine (Maywood, N.J.) 2003;228(5):564-7.
2003: Dettmer Todd S; Barnes Alicia; Iqbal Umar; Bailey Craig D C; Reynolds James N; Brien James F; Valenzuela C Fernando
Chronic prenatal ethanol exposure alters ionotropic glutamate receptor subunit protein levels in the adult guinea pig cerebral cortex.
Alcoholism, clinical and experimental research 2003;27(4):677-81.
2003: Appleton S D; Marks G S; Nakatsu K; Brien J F; Smith G N; Graham C H; Lash G E
Effects of hypoxia on heme oxygenase expression in human chorionic villi explants and immortalized trophoblast cells.
American journal of physiology. Heart and circulatory physiology 2003;284(3):H853-8.
2003: Hard Marjie L; Iqbal Umar; Brien James F; Koren Gideon
Binding of acetaldehyde to human and Guinea pig placentae in vitro.
Placenta 2003;24(2-3):149-54.
2003: Butters N S; Reynolds J N; Brien J F
Effects of chronic prenatal ethanol exposure on cGMP content and glutamate release in the hippocampus of the neonatal guinea pig.
Neurotoxicology and teratology 2003;25(1):59-68.
2003: Card Jeffrey W; Racz William J; Brien James F; Massey Thomas E
Attenuation of amiodarone-induced pulmonary fibrosis by vitamin E is associated with suppression of transforming growth factor-beta1 gene expression but not prevention of mitochondrial dysfunction.
The Journal of pharmacology and experimental therapeutics 2003;304(1):277-83.
2003: Lash G E; McLaughlin B E; MacDonald-Goodfellow S K; Smith G N; Brien J F; Marks G S; Nakatsu K; Graham C H
Relationship between tissue damage and heme oxygenase expression in chorionic villi of term human placenta.
American journal of physiology. Heart and circulatory physiology 2003;284(1):H160-7.
2003: Puri Rajan K; Reynolds James N; Brien James F
Effects of chronic prenatal ethanol exposure on NMDA receptor number and affinity for [3H]MK-801 in the cerebral cortex of the young postnatal and adult guinea-pig.
Reproduction, fertility, and development 2003;15(4):207-14.
2002: Richardson D P; Byrnes M L; Brien J F; Reynolds J N; Dringenberg H C
Impaired acquisition in the water maze and hippocampal long-term potentiation after chronic prenatal ethanol exposure in the guinea-pig.
The European journal of neuroscience 2002;16(8):1593-8.
2002: Bainbridge S A; Farley A E; McLaughlin B E; Graham C H; Marks G S; Nakatsu K; Brien J F; Smith G N
Carbon monoxide decreases perfusion pressure in isolated human placenta.
Placenta 2002;23(8-9):563-9.
2002: Hosein S; Marks G S; Brien J F; McLaughlin B E; Nakatsu K
An extracellular source of heme can induce a significant heme oxygenase mediated relaxation in the rat aorta.
Canadian journal of physiology and pharmacology 2002;80(8):761-5.
2002: Appleton Scott D; Marks Gerald S; Nakatsu Kanji; Brien James F; Smith Graeme N; Graham Charles H
Heme oxygenase activity in placenta: direct dependence on oxygen availability.
American journal of physiology. Heart and circulatory physiology 2002;282(6):H2055-9.
2002: Marks Gerald S; Vreman Hendrik J; McLaughlin Brian E; Brien James F; Nakatsu Kanji
Measurement of endogenous carbon monoxide formation in biological systems.
Antioxidants & redox signaling 2002;4(2):271-7.
2001: McLaughlin B E; Lash G E; Graham C H; Smith G N; Vreman H J; Stevenson D K; Marks G S; Nakatsu K; Brien J F
Endogenous carbon monoxide formation by chorionic villi of term human placenta.
Placenta 2001;22(10):886-8.
2001: Chung W H; Bennett B M; Racz W J; Brien J F; Massey T E
Induction of c-jun and TGF-beta 1 in Fischer 344 rats during amiodarone-induced pulmonary fibrosis.
American journal of physiology. Lung cellular and molecular physiology 2001;281(5):L1180-8.
2001: Bolt M W; Racz W J; Brien J F; Massey T E
Effects of vitamin E on cytotoxicity of amiodarone and N-desethylamiodarone in isolated hamster lung cells.
Toxicology 2001;166(3):109-18.
2001: Bolt M W; Card J W; Racz W J; Brien J F; Massey T E
Disruption of mitochondrial function and cellular ATP levels by amiodarone and N-desethylamiodarone in initiation of amiodarone-induced pulmonary cytotoxicity.
The Journal of pharmacology and experimental therapeutics 2001;298(3):1280-9.
2001: Dringenberg H C; Richardson D P; Brien J F; Reynolds J N
Spatial learning in the guinea pig: cued versus non-cued learning, sex differences, and comparison with rats.
Behavioural brain research 2001;124(1):97-101.
2001: Butters N S; Reynolds J N; Brien J F
In vitro ethanol exposure decreases potassium-stimulated, but not veratridine-stimulated, glutamate release in the guinea pig hippocampus.
Alcohol (Fayetteville, N.Y.) 2001;25(1):49-53.
2001: Byrnes M L; Reynolds J N; Brien J F
Effect of prenatal ethanol exposure during the brain growth spurt of the guinea pig.
Neurotoxicology and teratology 2001;23(4):355-64.
2001: Bailey C D; Brien J F; Reynolds J N
Chronic prenatal ethanol exposure increases GABA(A) receptor subunit protein expression in the adult guinea pig cerebral cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(12):4381-9.
2001: O'Reilly D A; McLaughlin B E; Marks G S; Brien J F; Nakatsu K
YC-1 enhances the responsiveness of tolerant vascular smooth muscle to glyceryl trinitrate.
Canadian journal of physiology and pharmacology 2001;79(1):43-8.
2000: McLaughlin B E; Hutchinson J M; Graham C H; Smith G N; Marks G S; Nakatsu K; Brien J F
Heme oxygenase activity in term human placenta.
Placenta 2000;21(8):870-3.
2000: Kimura K A; Reynolds J N; Brien J F
Ethanol neurobehavioral teratogenesis and the role of the hippocampal glutamate-N-methyl-D-aspartate receptor-nitric oxide synthase system.
Neurotoxicology and teratology 2000;22(5):607-16.
2000: Butters N S; Gibson M A; Reynolds J N; Brien J F
Effects of chronic prenatal ethanol exposure on hippocampal glutamate release in the postnatal guinea pig.
Alcohol (Fayetteville, N.Y.) 2000;21(1):1-9.
2000: McLaughlin B E; Chretien M L; Choi C; Brien J F; Nakatsu K; Marks G S
Potentiation of carbon monoxide-induced relaxation of rat aorta by YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole].
Canadian journal of physiology and pharmacology 2000;78(4):343-9.
2000: Gibson M A; Butters N S; Reynolds J N; Brien J F
Effects of chronic prenatal ethanol exposure on locomotor activity, and hippocampal weight, neurons, and nitric oxide synthase activity of the young postnatal guinea pig.
Neurotoxicology and teratology 2000;22(2):183-92.
2000: Crowe A C; Chang M E; McLaughlin B E; Brien J F
Nitric oxide formation from glyceryl trinitrate in the developing guinea-pig hippocampus.
Reproduction, fertility, and development 2000;12(5-6):245-9.
1999: Bailey C D; Brien J F; Reynolds J N
Altered GABA(A)-benzodiazepine receptor number and pharmacology in the adult guinea pig cerebral cortex after chronic prenatal ethanol exposure.
Alcoholism, clinical and experimental research 1999;23(11):1816-24.
1999: Appleton S D; Chretien M L; McLaughlin B E; Vreman H J; Stevenson D K; Brien J F; Nakatsu K; Maurice D H; Marks G S
Selective inhibition of heme oxygenase, without inhibition of nitric oxide synthase or soluble guanylyl cyclase, by metalloporphyrins at low concentrations.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(10):1214-9.
1999: Kimura K A; Reynolds J N; Brien J F
Ontogeny of nitric oxide synthase I and III protein expression and enzymatic activity in the guinea pig hippocampus.
Brain research. Developmental brain research 1999;116(2):211-6.
1999: Kimura K A; Chiu J; Reynolds J N; Brien J F
Effect of chronic prenatal ethanol exposure on nitric oxide synthase I and III proteins in the hippocampus of the near-term fetal guinea pig.
Neurotoxicology and teratology 1999;21(3):251-9.
1999: Hussain A S; Crispino N H; McLaughlin B E; Brien J F; Marks G S; Nakatsu K
Glyceryl trinitrate-induced vasodilation is inhibited by ultraviolet irradiation despite enhanced nitric oxide generation: evidence for formation of a nitric oxide conjugate.
The Journal of pharmacology and experimental therapeutics 1999;289(2):895-900.
1999: Card J W; Leeder R G; Racz W J; Brien J F; Bray T M; Massey T E
Effects of dietary vitamin E supplementation on pulmonary morphology and collagen deposition in amiodarone- and vehicle-treated hamsters.
Toxicology 1999;133(2-3):75-84.
1999: Chiu J; Brien J F; Wu P; Eubanks J H; Zhang L; Reynolds J N
Chronic ethanol exposure alters MK-801 binding sites in the cerebral cortex of the near-term fetal guinea pig.
Alcohol (Fayetteville, N.Y.) 1999;17(3):215-21.
1999: Bailey C D; Brien J F; Reynolds J N
Neurosteroid modulation of the GABAA receptor in the developing guinea pig cerebral cortex.
Brain research. Developmental brain research 1999;113(1-2):21-8.
1998: Odrcich M J; Graham C H; Kimura K A; McLaughlin B E; Marks G S; Nakatsu K; Brien J F
Heme oxygenase and nitric oxide synthase in the placenta of the guinea-pig during gestation.
Placenta 1998;19(7):509-16.
1998: Card J W; Lalonde B R; Rafeiro E; Tam A S; Racz W J; Brien J F; Bray T M; Massey T E
Amiodarone-induced disruption of hamster lung and liver mitochondrial function: lack of association with thiobarbituric acid-reactive substance production.
Toxicology letters 1998;98(1-2):41-50.
1998: Smith G N; Brien J F
Use of nitroglycerin for uterine relaxation.
Obstetrical & gynecological survey 1998;53(9):559-65.
1998: Bolt M W; Racz W J; Brien J F; Bray T M; Massey T E
Differential susceptibilities of isolated hamster lung cell types to amiodarone toxicity.
Canadian journal of physiology and pharmacology 1998;76(7-8):721-7.
1998: Vukomanovic D V; Hussain A; Zoutman D E; Marks G S; Brien J F; Nakatsu K
Analysis of nanomolar S-nitrosothiol concentrations in physiological media.
Journal of pharmacological and toxicological methods 1998;39(4):235-40.
1998: Kearney M F; Brien J F; Marks G S; Lei H; Nakatsu K
Thiol agents separate nitric oxide formation from vasodilation induced by glyceryl trinitrate.
Drug metabolism and disposition: the biological fate of chemicals 1998;26(6):547-51.
1998: Kimura K A; Brien J F
Hippocampal nitric oxide synthase in the fetal guinea pig: effects of chronic prenatal ethanol exposure.
Brain research. Developmental brain research 1998;106(1-2):39-46.
1997: Hussain A S; Marks G S; Brien J F; Nakatsu K
The soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3-alpha]quinoxalin-1-one (ODQ) inhibits relaxation of rabbit aortic rings induced by carbon monoxide, nitric oxide, and glyceryl trinitrate.
Canadian journal of physiology and pharmacology 1997;75(8):1034-7.
1997: Hussain A S; Abu-Zahra T N; Brien J F; Marks G S; Nakatsu K
Thiol agents potentiate glyceryl trinitrate mediated relaxation of rabbit taenia coli: evidence for thiol-dependent biotransformation.
Canadian journal of physiology and pharmacology 1997;75(7):807-11.
1997: Marks G S; McLaughlin B E; Vreman H J; Stevenson D K; Nakatsu K; Brien J F; Pang S C
Heme oxygenase activity and immunohistochemical localization in bovine pulmonary artery and vein.
Journal of cardiovascular pharmacology 1997;30(1):1-6.
1997: Cook M N; Marks G S; Vreman H J; McLaughlin B E; Nakatsu K; Stevenson D K; Brien J F
Carbon monoxide formation in the guinea pig hippocampus: ontogeny and effect of in vitro ethanol exposure.
Brain research. Developmental brain research 1997;101(1-2):283-6.
1997: Hussain A S; Bozinovski J; Maurice D H; McLaughlin B E; Marks G S; Brien J F; Nakatsu K
Inhibition of the action of nitric oxide prodrugs by pyocyanin: mechanistic studies.
Canadian journal of physiology and pharmacology 1997;75(5):398-406.
1997: Cook M N; Marks G S; Vreman H J; Nakatsu K; Stevenson D K; Brien J F
Heme oxygenase activity and acute and chronic ethanol exposure in the hippocampus, frontal cerebral cortex, and cerebellum of the near-term fetal guinea pig.
Alcohol (Fayetteville, N.Y.) 1997;14(2):117-24.
1997: Vukomanovic D V; Zoutman D E; Stone J A; Marks G S; Brien J F; Nakatsu K
Electrospray mass-spectrometric, spectrophotometric and electrochemical methods do not provide evidence for the binding of nitric oxide by pyocyanine at pH 7.
The Biochemical journal 1997;322 ( Pt 1)():25-9.
1996: Vukomanovic D V; Zoutman D E; Marks G S; Brien J F; van Loon G W; Nakatsu K
Analysis of pyocyanin from Pseudomonas aeruginosa by adsorptive stripping voltammetry.
Journal of pharmacological and toxicological methods 1996;36(2):97-102.
1996: Watson C S; White S E; Homan J; Abdollah S; Brien J F; Challis J R; Bocking A D
Fetal breathing is not inhibited by ethanol exposure during prolonged reduced uterine blood flow.
Canadian journal of physiology and pharmacology 1996;74(9):1016-24.
1996: Kimura K A; Parr A M; Brien J F
Effect of chronic maternal ethanol administration on nitric oxide synthase activity in the hippocampus of the mature fetal guinea pig.
Alcoholism, clinical and experimental research 1996;20(5):948-53.
1996: Hussain A S; Brien J F; Marks G S; Nakatsu K
Superoxide does not inhibit glyceryl trinitrate-rabbit aortic strip-mediated relaxation of rabbit Taenia coli. Evidence against a role for nitric oxide itself as the smooth muscle active drug metabolite?
Drug metabolism and disposition: the biological fate of chemicals 1996;24(7):780-5.
1996: Cook M N; Marks G S; Vreman H J; Nakatsu K; Stevenson D K; Brien J F
Ontogeny of heme oxygenase activity in the hippocampus, frontal cerebral cortex, and cerebellum of the guinea pig.
Brain research. Developmental brain research 1996;92(1):18-23.
1996: Leeder R G; Rafeiro E; Brien J F; Mandin C C; Massey T E
Evaluation of reactive oxygen species involvement in amiodarone pulmonary toxicity in vivo and in vitro.
Journal of biochemical toxicology 1996;11(3):147-60.
1996: Brien J F; McLaughlin B E; Nakatsu K; Marks G S
Chemiluminescence headspace-gas analysis for determination of nitric oxide formation in biological systems.
Methods in enzymology 1996;268():83-92.
1995: Massey T E; Leeder R G; Rafeiro E; Brien J F
Mechanisms in the pathogenesis of amiodarone-induced pulmonary toxicity.
Canadian journal of physiology and pharmacology 1995;73(12):1675-85.
1995: Marks G S; McLaughlin B E; Jimmo S L; Poklewska-Koziell M; Brien J F; Nakatsu K
Time-dependent increase in nitric oxide formation concurrent with vasodilation induced by sodium nitroprusside, 3-morpholinosydnonimine, and S-nitroso-N-acetylpenicillamine but not by glyceryl trinitrate.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(11):1248-52.
1995: Reynolds J D; Brien J F
Ethanol neurobehavioural teratogenesis and the role of L-glutamate in the fetal hippocampus.
Canadian journal of physiology and pharmacology 1995;73(9):1209-23.
1995: Liu Z G; McLaughlin B E; Marks G S; Brien J F; Nakatsu K
Sulfhydryl involvement in nitric oxide sequestration and nitric oxide induced guanylyl cyclase activation in vascular smooth muscle.
Canadian journal of physiology and pharmacology 1995;73(8):1144-8.
1995: Bobier H S; Smith G N; Pancham S R; Brien J F
Comparative study of sodium nitroprusside induced vasodilation of human placental veins from premature and full-term normotensive and preeclamptic pregnancy.
Canadian journal of physiology and pharmacology 1995;73(8):1118-22.
1995: Abdollah S; Brien J F
Effect of chronic maternal ethanol administration on glutamate and N-methyl-D-aspartate binding sites in the hippocampus of the near-term fetal guinea pig.
Alcohol (Fayetteville, N.Y.) 1995;12(4):377-82.
1995: Abdollah S; Brien J F
Glutamate and N-methyl-D-aspartate binding sites in the guinea pig hippocampus: ontogeny and effect of acute in vitro ethanol exposure.
Alcohol (Fayetteville, N.Y.) 1995;12(4):369-75.
1995: Brien J F; Reynolds J D; Cunningham M A; Parr A M; Waddock S; Kalisch B E
Nitric oxide synthase activity in the hippocampus, frontal cerebral cortex, and cerebellum of the guinea pig: ontogeny and in vitro ethanol exposure.
Alcohol (Fayetteville, N.Y.) 1995;12(4):329-33.
1995: Cook M N; Nakatsu K; Marks G S; McLaughlin B E; Vreman H J; Stevenson D K; Brien J F
Heme oxygenase activity in the adult rat aorta and liver as measured by carbon monoxide formation.
Canadian journal of physiology and pharmacology 1995;73(4):515-8.
1995: Reynolds J D; Brien J F
The role of adenosine A1 receptor activation in ethanol-induced inhibition of stimulated glutamate release in the hippocampus of the fetal and adult guinea pig.
Alcohol (Fayetteville, N.Y.) 1995;12(2):151-7.
1995: Catlin M C; Penning D H; Brien J F
Effect of exposure in vitro to ethanol and hypoxia on gamma-aminobutyric acid efflux in the hippocampus of the fetal and adult guinea-pig.
Reproduction, fertility, and development 1995;7(5):1339-44.
1994: Hussain A S; Poklewska-Koziell M; Brien J F; Marks G S; Nakatsu K
Nitric oxide formation from glyceryl trinitrate by rabbit aortic strip: detection by rabbit taenia coli concurrent with vasorelaxation.
British journal of pharmacology 1994;113(4):1508-14.
1994: Leeder R G; Evans C D; Brien J F; Massey T E
Resistance of the hamster to amiodarone-induced pulmonary toxicity following repeated intraperitoneal administration.
Toxicology letters 1994;74(1):51-9.
1994: Rafeiro E; Leeder R G; Brien J F; Kabalka G W; Chatla N; Massey T E
Comparison of the in vivo pulmonary toxicity of amiodarone and des-oxo-amiodarone in the hamster.
Toxicology and applied pharmacology 1994;127(2):275-81.
1994: Bozinovski J; Brien J F; Marks G S; Nakatsu K
Inhibition of nitrovasodilators by pyocyanin and methylene blue is dissociated from nitric oxide formation.
Canadian journal of physiology and pharmacology 1994;72(7):746-52.
1994: Leeder R G; Brien J F; Massey T E
Investigation of the role of oxidative stress in amiodarone-induced pulmonary toxicity in the hamster.
Canadian journal of physiology and pharmacology 1994;72(6):613-21.
1994: Booth B P; Brien J F; Marks G S; Milne B; Cervenko F; Pym J; Knight J; Rogers K; Salerno T; Nakatsu K
The effects of hypothermic and normothermic cardiopulmonary bypass on glyceryl trinitrate activity.
Anesthesia and analgesia 1994;78(5):848-56.
1994: Reynolds J D; Brien J F
Effects of acute ethanol exposure on glutamate release in the hippocampus of the fetal and adult guinea pig.
Alcohol (Fayetteville, N.Y.) 1994;11(3):259-67.
1994: Bocking A D; Carmichael L J; Abdollah S; Sinervo K R; Smith G N; Brien J F
Effect of ethanol on immature ovine fetal breathing movements, fetal prostaglandin E2, and myometrial activity.
The American journal of physiology 1994;266(4 Pt 2):R1297-301.
1993: Beaton E D; Liu Z; McLaughlin B E; Brien J F; Nakatsu K; Marks G S
A novel method for detection of nitric oxide binding sites by using a chemiluminescence-headspace gas technique.
Journal of pharmacological and toxicological methods 1993;30(4):217-22.
1993: Liu Z; Nakatsu K; Brien J F; Beaton E D; Marks G S; Maurice D H
Selective sequestration of nitric oxide by subcellular components of vascular smooth muscle and platelets: relationship to nitric oxide stimulation of the soluble guanylyl cyclase.
Canadian journal of physiology and pharmacology 1993;71(12):938-45.
1993: Abdollah S; Catlin M C; Brien J F
Ethanol neuro-behavioural teratogenesis in the guinea pig: behavioural dysfunction and hippocampal morphologic change.
Canadian journal of physiology and pharmacology 1993;71(10-11):776-82.
1993: Marks G S; Nakatsu K; Brien J F
Does endogenous zinc protoporphyrin modulate carbon monoxide formation from heme? Implications for long-term potentiation, memory, and cognitive function.
Canadian journal of physiology and pharmacology 1993;71(10-11):753-4.
1993: Bocking A D; Sinervo K R; Smith G N; Carmichael L; Challis J R; Olson D M; Brien J F
Increased uteroplacental production of prostaglandin E2 during ethanol infusion.
The American journal of physiology 1993;265(3 Pt 2):R640-5.
1993: Booth B P; Brien J F; Marks G S; Nakatsu K
Effect of temperature on glyceryl trinitrate induced relaxation of rabbit aorta.
Canadian journal of physiology and pharmacology 1993;71(8):629-32.
1993: Liu Z; Brien J F; Marks G S; McLaughlin B E; Nakatsu K
Lack of evidence for the involvement of cytochrome P-450 or other hemoproteins in metabolic activation of glyceryl trinitrate in rabbit aorta.
The Journal of pharmacology and experimental therapeutics 1993;264(3):1432-9.
1993: Catlin M C; Abdollah S; Brien J F
Dose-dependent effects of prenatal ethanol exposure in the guinea pig.
Alcohol (Fayetteville, N.Y.) 1993;10(2):109-15.
1992: Reynolds J D; Brien J F
Ontogeny of glutamate and gamma-aminobutyric acid release in the hippocampus of the guinea pig.
Journal of developmental physiology 1992;18(5):243-52.
1992: Nakatsu K; Brien J F; Savard G; Toffelmire E B; Abdollah H; Bennett B M; Marks G S
Plasma disposition and hemodynamic effects of a single oral dose of isosorbide dinitrate in human males and females.
Biopharmaceutics & drug disposition 1992;13(5):357-67.
1992: Sinervo K R; Smith G N; Bocking A D; Patrick J; Brien J F
Effect of ethanol on the release of prostaglandins from ovine fetal brain stem during gestation.
Alcoholism, clinical and experimental research 1992;16(3):443-8.
1992: Marks G S; McLaughlin B E; Nakatsu K; Brien J F
Biotransformation of glyceryl trinitrate by rat brain homogenate.
Canadian journal of physiology and pharmacology 1992;70(6):935-7.
1992: Marks G S; McLaughlin B E; Nakatsu K; Brien J F
Direct evidence for nitric oxide formation from glyceryl trinitrate during incubation with intact bovine pulmonary artery.
Canadian journal of physiology and pharmacology 1992;70(2):308-11.
1992: Liu Z; Brien J F; Marks G S; McLaughlin B E; Nakatsu K
Carbon monoxide does not inhibit glyceryl trinitrate biotransformation by or relaxation of aorta.
European journal of pharmacology 1992;211(1):129-32.
1991: Penning D H; Patrick J; Jimmo S; Brien J F
Release of glutamate and gamma-aminobutyric acid in the ovine fetal hippocampus: ontogeny and effect of hypoxia.
Journal of developmental physiology 1991;16(5):301-7.
1991: Smith G N; Sinervo K R; Carmichael L; Patrick J; Bocking A D; Brien J F
The effects of indomethacin and prostaglandin E2 on the ethanol-induced suppression of ovine fetal breathing movements.
Journal of developmental physiology 1991;16(4):239-42.
1991: Marks G S; McLaughlin B E; Brown L B; Beaton D E; Booth B P; Nakatsu K; Brien J F
Interaction of glyceryl trinitrate and sodium nitroprusside with bovine pulmonary vein homogenate and 10,000 x g supernatant: biotransformation and nitric oxide formation.
Canadian journal of physiology and pharmacology 1991;69(6):889-92.
1991: Abdollah H; Brennan F J; Jimmo S; Brien J F
Relationship between myocardial amiodarone concentration and antiarrhythmic effect in dogs with myocardial infarction and electrically induced ventricular arrhythmias.
Canadian journal of physiology and pharmacology 1991;69(6):812-7.
1991: Nakatsu K; Pym J; Witte S; Marks G S; Brien J F
Adrenoceptors of the human internal thoracic artery.
Canadian journal of physiology and pharmacology 1991;69(6):792-7.
1991: Smith G N; Patrick J; Sinervo K R; Brien J F
Effects of ethanol exposure on the embryo-fetus: experimental considerations, mechanisms, and the role of prostaglandins.
Canadian journal of physiology and pharmacology 1991;69(5):550-69.
1991: Marks G S; Brien J F; Nakatsu K; McLaughlin B E
Does carbon monoxide have a physiological function?
Trends in pharmacological sciences 1991;12(5):185-8.
1991: Brennan F J; Brien J F; Armstrong P W
Plasma concentration time course and pharmacological effects of a standardized oral amiodarone dosing regimen in humans.
The Canadian journal of cardiology 1991;7(3):117-24.
1991: Booth B P; Henderson M; Milne B; Cervenko F; Marks G S; Brien J F; Nakatsu K
Sequestration of glyceryl trinitrate (nitroglycerin) by cardiopulmonary bypass oxygenators.
Anesthesia and analgesia 1991;72(4):493-7.
1991: Treissman D; Brien J F
Fetal guinea pig brain 15-hydroxyprostaglandin dehydrogenase: ontogeny and effect of ethanol.
Alcohol (Fayetteville, N.Y.) 1991;8(2):97-102.
1991: Brien J F; McLaughlin B E; Nakatsu K; Marks G S
Quantitation of nitric oxide formation from nitrovasodilator drugs by chemiluminescence analysis of headspace gas.
Journal of pharmacological methods 1991;25(1):19-27.
1991: Brien J F; Smith G N
Effects of alcohol (ethanol) on the fetus.
Journal of developmental physiology 1991;15(1):21-32.
1991: Treissman D; Smith G N; Patrick J; Brien J F
Effect of ethanol on 15-hydroxyprostaglandin dehydrogenase activity in the brain stem of the near-term fetal sheep.
Developmental pharmacology and therapeutics 1991;16(1):48-52.
1990: Booth B P; Bennett B M; Brien J F; Elliott D A; Marks G S; McCans J L; Nakatsu K
Assay of glyceryl trinitrate, isosorbide dinitrate, and their metabolites in plasma by large-bore capillary column gas-liquid chromatography.
Biopharmaceutics & drug disposition 1990;11(8):663-77.
1990: Brien J F; Jimmo S; Brennan F J; Armstrong P W; Abdollah H
Disposition of amiodarone and its proximate metabolite, desethylamiodarone, in the dog for oral administration of single-dose and short-term drug regimens.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(6):846-51.
1990: Daniels J M; Leeder R G; Brien J F; Massey T E
Repeated amiodarone exposure in the rat: toxicity and effects on hepatic and extrahepatic monooxygenase activities.
Canadian journal of physiology and pharmacology 1990;68(9):1261-8.
1990: Smith G N; Brien J F; Homan J; Carmichael L; Treissman D; Patrick J
Effect of ethanol on ovine fetal and maternal plasma prostaglandin E2 concentrations and fetal breathing movements.
Journal of developmental physiology 1990;14(1):23-8.
1990: Smith G N; Brien J F; Homan J; Carmichael L; Patrick J
Indomethacin reversal of ethanol-induced suppression of ovine fetal breathing movements and relationship to prostaglandin E2.
Journal of developmental physiology 1990;14(1):29-35.
1990: Rafeiro E; Leeder R G; Daniels J M; Brien J F; Massey T E
In vitro hepatic, renal, and pulmonary N-dealkylation of amiodarone.
Biochemical pharmacology 1990;39(10):1627-9.
1990: Penning D H; Patrick J; Brien J
Effects of hypoxia on release of amino acid neurotransmitters from fetal lamb brain in vitro.
Canadian journal of anaesthesia = Journal canadien d'anesthésie 1990;37(4 Pt 2):S2.
1990: Abdollah H; Brien J F; Brennan F J
Antiarrhythmic effect of chronic oral amiodarone treatment in dogs with myocardial infarction and reproducibly inducible sustained ventricular arrhythmias.
Journal of cardiovascular pharmacology 1990;15(5):799-807.
1990: Kawamoto J H; McLaughlin B E; Brien J F; Marks G S; Nakatsu K
Biotransformation of glyceryl trinitrate and elevation of cyclic GMP precede glyceryl trinitrate-induced vasodilation.
Journal of cardiovascular pharmacology 1990;15(5):714-9.
1989: Slack C J; McLaughlin B E; Brien J F; Marks G S; Nakatsu K
Biotransformation of glyceryl trinitrate and isosorbide dinitrate in vascular smooth muscle made tolerant to organic nitrates.
Canadian journal of physiology and pharmacology 1989;67(11):1381-5.
1989: Daniels J M; Brien J F; Massey T E
Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone.
Toxicology and applied pharmacology 1989;100(2):350-9.
1989: Card S E; Tompkins S F; Brien J F
Ontogeny of the activity of alcohol dehydrogenase and aldehyde dehydrogenases in the liver and placenta of the guinea pig.
Biochemical pharmacology 1989;38(15):2535-41.
1989: Smith G N; Brien J F; Homan J; Carmichael L; Patrick J
Indomethacin antagonizes the ethanol-induced suppression of breathing activity but not the suppression of brain activity in the near-term fetal sheep.
Journal of developmental physiology 1989;12(2):69-75.
1989: Card S E; Brien J F
No effect of chronic ethanol administration on the activity of alcohol dehydrogenase and aldehyde dehydrogenases in the near-term pregnant guinea pig.
Canadian journal of physiology and pharmacology 1989;67(6):601-6.
1989: Smith G N; Brien J F; Carmichael L; Clarke D W; Patrick J
Effect of acute, multiple-dose ethanol on maternal and fetal blood gases and acid-base balance in the near-term pregnant ewe.
Canadian journal of physiology and pharmacology 1989;67(6):686-8.
1989: Marks G S; McLaughlin B E; MacMillan H F; Nakatsu K; Brien J F
Differential biotransformation of glyceryl trinitrate by red blood cell-supernatant fraction and pulmonary vein homogenate.
Canadian journal of physiology and pharmacology 1989;67(5):417-22.
1989: Smith G N; Brien J F; Carmichael L; Homan J; Clarke D W; Patrick J
Development of tolerance to ethanol-induced suppression of breathing movements and brain activity in the near-term fetal sheep during short-term maternal administration of ethanol.
Journal of developmental physiology 1989;11(3):189-97.
1989: Abdollah H; Brien J F; Brennan F J
Antiarrhythmic effects of desethylamiodarone in dogs with subacute myocardial infarction and inducible ventricular arrhythmias.
Journal of cardiovascular pharmacology 1989;13(1):37-44.
1989: Clarke D W; Smith G N; Patrick J; Richardson B; Brien J F
Activity of alcohol dehydrogenase and aldehyde dehydrogenase in maternal liver, fetal liver and placenta of the near-term pregnant ewe.
Developmental pharmacology and therapeutics 1989;12(1):35-41.
1989: Marks G S; Nakatsu K; McLaughlin B; Kawamoto J; Slack C; Brien J F
The role of nitric oxide formation in organic nitrate-induced vasodilation and organic nitrate tolerance.
Zeitschrift für Kardiologie 1989;78 Suppl 2():18-21; discussion 64-7.
1988: Slack C J; McLaughlin B E; Nakatsu K; Marks G S; Brien J F
Nitric oxide-induced vasodilation of organic nitrate-tolerant rabbit aorta.
Canadian journal of physiology and pharmacology 1988;66(10):1344-6.
1988: Clark D W; Smith G N; Patrick J; Richardson B; Brien J F
Disposition of ethanol and its proximate metabolite, acetaldehyde, in the near-term pregnant ewe for short term maternal administration of moderate-dose ethanol.
Drug metabolism and disposition: the biological fate of chemicals 1988;16(3):464-8.
1988: Nakatsu K; Kawamoto J H; Brien J F; Marks G S
A facile, reliable method for staining blood vessel endothelium.
Journal of pharmacological methods 1988;19(2):149-54.
1988: Tam G S; MacMillan H; Bennett B M; Marks G S; Brien J F; Nakatsu K
Patterns of isosorbide dinitrate and glyceryl trinitrate metabolites formed by selected segments of the rabbit gastrointestinal tract.
Canadian journal of physiology and pharmacology 1988;66(2):166-70.
1988: Kawamoto J H; Brien J F; Marks G S; Nakatsu K
Mechanism of glyceryl trinitrate-induced vasodilation. II. Lack of evidence for specific binding of GTN to bovine pulmonary vein.
The Journal of pharmacology and experimental therapeutics 1988;244(1):328-34.
1988: Brien J F; McLaughlin B E; Kobus S M; Kawamoto J H; Nakatsu K; Marks G S
Mechanism of glyceryl trinitrate-induced vasodilation. I. Relationship between drug biotransformation, tissue cyclic GMP elevation and relaxation of rabbit aorta.
The Journal of pharmacology and experimental therapeutics 1988;244(1):322-7.
1987: Tam G S; Marks G S; Brien J F; Nakatsu K
Sex- and species-related differences in the biotransformation of isosorbide dinitrate by various tissues of the rabbit and rat.
Canadian journal of physiology and pharmacology 1987;65(7):1478-83.
1987: Kawamoto J H; Brien J F; Marks G S; Nakatsu K
A comparative study of glyceryl trinitrate biotransformation and glyceryl trinitrate induced relaxation in bovine pulmonary artery and vein.
Canadian journal of physiology and pharmacology 1987;65(6):1146-50.
1987: Brien J F; Jimmo S; Brennan F J; Ford S E; Armstrong P W
Distribution of amiodarone and its metabolite, desethylamiodarone, in human tissues.
Canadian journal of physiology and pharmacology 1987;65(3):360-4.
1987: Tam G S; Nakatsu K; Brien J F; Marks G S
Determination of isosorbide dinitrate biotransformation in various tissues of the rabbit by capillary column gas-liquid chromatography.
Biopharmaceutics & drug disposition 1987;8(1):37-45.
1986: Nakatsu K; Vandenberghe M; Kobus S; Kawamoto J; Brien J F; Marks G S
Endothelium-dependent relaxation of rabbit aorta by acetylcholine requires ethylenediaminetetraacetic acid.
Canadian journal of physiology and pharmacology 1986;64(7):1050-2.
1986: Bennett B M; Kobus S M; Brien J F; Nakatsu K; Marks G S
Requirement for reduced, unliganded hemoprotein for the hemoglobin- and myoglobin-mediated biotransformation of glyceryl trinitrate.
The Journal of pharmacology and experimental therapeutics 1986;237(2):629-35.
1984: Bennett B M; Tam G S; Van Alstyne K; Brien J F; Nakatsu K; Marks G S
Effect of 5-isosorbide mononitrate on isosorbide dinitrate-induced relaxation of rabbit aortic rings.
Canadian journal of physiology and pharmacology 1984;62(9):1194-7.

Sign-in to see more