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Pearlly Yan

Research Profile

Physiology

Chemicals & Drugs

Devices

Oligonucleotide Array Sequence Analysis

Anatomy

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Genes & Molecular Sequences

Genome, Human

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Publications

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Anna von dem Knesebeck; Anke Waha; Pearlly S Yan; Elmar Endl; Jörg Felsberg; Martin Glas; Jennifer Hammes; Wolfgang Hartmann; Thomas Mikeska; Torsten Pietsch; Guido Reifenberger; Björn Scheffler; Matthias Simon; Andreas Waha
RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas.
Daniel M Bornman; Ralf Bundschuh; Michael L Dickens; Christine H Baker; Curt A Barden; Gene D Godbold; Mark E Hester; Manjula D Kasoji; Angela Minard-Smith; Scott C Nelson; Benjamin Rodriguez; Jared M Schuetter; Ivan E Tornes; Jacquelyn E Walther; Pearlly S Yan; Boyu Yang; Brian A Young; Seth A Faith
Short-read, high-throughput sequencing technology for STR genotyping.
Alexey Palamarchuk; Laura Rassenti; Benjamin Rodrigues; Linan Wang; Pearlly S Yan; nicola zanesi; Hansjuerg Alder; Veronica Balatti; Arianna Bottoni; Carlo M Croce; Michael Freitas; Thomas J Kipps; Mark Murphy; Natalya Nazaryan; yuri pekarsky
Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL).

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All Publications

2012: Anna von dem Knesebeck; Anke Waha; Pearlly S Yan; Elmar Endl; Jörg Felsberg; Martin Glas; Jennifer Hammes; Wolfgang Hartmann; Thomas Mikeska; Torsten Pietsch; Guido Reifenberger; Björn Scheffler; Matthias Simon; Andreas Waha
RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas.
Neoplasia (New York, N.Y.) 2012;14(6):526-34.
2012: Daniel M Bornman; Ralf Bundschuh; Michael L Dickens; Christine H Baker; Curt A Barden; Gene D Godbold; Mark E Hester; Manjula D Kasoji; Angela Minard-Smith; Scott C Nelson; Benjamin Rodriguez; Jared M Schuetter; Ivan E Tornes; Jacquelyn E Walther; Pearlly S Yan; Boyu Yang; Brian A Young; Seth A Faith
Short-read, high-throughput sequencing technology for STR genotyping.
BioTechniques 2012;0(0):1-6.
2012: Alexey Palamarchuk; Laura Rassenti; Benjamin Rodrigues; Linan Wang; Pearlly S Yan; nicola zanesi; Hansjuerg Alder; Veronica Balatti; Arianna Bottoni; Carlo M Croce; Michael Freitas; Thomas J Kipps; Mark Murphy; Natalya Nazaryan; yuri pekarsky
Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL).
Proceedings of the National Academy of Sciences of the United States of America 2012;109(7):2555-60.
2012: Diego Villar; Pearlly S Yan; Ana Dopazo; Laura Gómez-Maldonado; Hubert Hackl; Tim H M Huang; Amaya Ortiz-Barahona; Nuria Pescador; Benjamin A T Rodriguez; Fátima Sánchez-Cabo; Zlatko Trajanoski; Luis del Peso
Cooperativity of stress-responsive transcription factors in core hypoxia-inducible factor binding regions.
PloS one 2012;7(9):e45708.
2011: Kun-Tu Yeh; Gary C W Chen; Lin-Yu Chen; Tze-Ho Chen; Yu-Hsin Chen; Jian-Liang Chou; Daniel E Deatherage; Hui-Ming (Tim) Huang; Yi-Wen Huang; Hung-Cheng Lai; Huey-Jen Lin; Ru-Inn Lin; Kenneth P Nephew; Her-Young Su; Pearlly S Yan; Hui-Wen Yang; Chia-Ming Yeh; Michael W Y Chan
Aberrant TGFβ/SMAD4 signaling contributes to epigenetic silencing of a putative tumor suppressor, RunX1T1 in ovarian cancer.
Epigenetics : official journal of the DNA Methylation Society 2011;6(6):727-39.
2011: Benjamin A T Rodriguez; Yu-I Weng; Ta-Ming Liu; Tao Zuo; Pei-Yin Hsu; Ching-Hung Lin; Ann-Lii Cheng; Hengmi Cui; Pearlly S Yan; Hui-Ming (Tim) Huang
Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells.
Carcinogenesis 2011;32(6):812-21.
2011: Eddy H J van Roon; Noël F C C de Miranda; Merlijn P van Nieuwenhuizen; Emile J de Meijer; Marjo Van Puijenbroek; Pearlly S Yan; Hui-Ming (Tim) Huang; Tom van Wezel; Hans Morreau; Judith M Boer
Tumour-specific methylation of PTPRG intron 1 locus in sporadic and Lynch syndrome colorectal cancer.
European journal of human genetics : EJHG 2011;19(3):307-12.
2011: Shuying Sun; Pearlly S Yan; Hui-Ming (Tim) Huang; Yi-Wen Huang; Shili Lin
Preprocessing differential methylation hybridization microarray data.
BioData mining 2011;4():13.
2011: Shuying Sun; Zhengyi Chen; Pearlly S Yan; Yi-Wen Huang; Hui-Ming (Tim) Huang; Shili Lin
Identifying hypermethylated CpG islands using a quantile regression model.
BMC bioinformatics 2011;12():54.
2011: Chia-Chen Hsu; Yu-Wei Leu; Min-Jen Tseng; Kuan-Der Lee; Tzen-Yu Kuo; Jia-Yi Yen; Yen-Ling Lai; Yi-Chen Hung; Wei-Sheng Sun; Chien-Min Chen; Pei-Yi Chu; Kun-Tu Yeh; Pearlly S Yan; Yu-Sun Chang; Hui-Ming (Tim) Huang; Shu-Huei Hsiao
Functional characterization of Trip10 in cancer cell growth and survival.
Journal of biomedical science 2011;18():12.
2010: Shu-Huei Hsiao; Kuan-Der Lee; Chia-Chen Hsu; Min-Jen Tseng; Victor X Jin; Wei-Sheng Sun; Yi-Chen Hung; Kun-Tu Yeh; Pearlly S Yan; Yen-Yu Lai; H Sunny Sun; Yen-Jung Lu; Yu-Sun Chang; Shaw-Jenq Tsai; Hui-Ming (Tim) Huang; Yu-Wei Leu
DNA methylation of the Trip10 promoter accelerates mesenchymal stem cell lineage determination.
Biochemical and biophysical research communications 2010;400(3):305-12.
2010: Pei-Yin Hsu; Hang-Kai Hsu; Gregory A C Singer; Pearlly S Yan; Benjamin A T Rodriguez; Joseph C Liu; Yu-I Weng; Daniel E Deatherage; Zhong Chen; Julia S Pereira; Ricardo Lopez; Jose Russo; Qianben Wang; Coral A Lamartiniere; Kenneth P Nephew; Hui-Ming (Tim) Huang
Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping.
Genome research 2010;20(6):733-44.
2010: Jian-Liang Chou; Her-Young Su; Lin-Yu Chen; Yu-Ping Liao; Corinna Hartman-Frey; Yi-Hui Lai; Hui-Wen Yang; Daniel E Deatherage; Chieh-Ti Kuo; Yi-Wen Huang; Pearlly S Yan; Shu-Huei Hsiao; Chien-Kuo Tai; Huey-Jen L Lin; Ramana V Davuluri; Tai-Kuang Chao; Kenneth P Nephew; Hui-Ming (Tim) Huang; Hung-Cheng Lai; Michael W Y Chan
Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer.
Laboratory investigation; a journal of technical methods and pathology 2010;90(3):414-25.
2010: Andreas Waha; Jörg Felsberg; Wolfgang Hartmann; Anna von dem Knesebeck; Thomas Mikeska; Stefan Joos; Marietta Wolter; Arend Koch; Pearlly S Yan; Elmar Endl; Otmar D Wiestler; Guido Reifenberger; Torsten Pietsch; Andreas Waha
Epigenetic downregulation of mitogen-activated protein kinase phosphatase MKP-2 relieves its growth suppressive activity in glioma cells.
Cancer research 2010;70(4):1689-99.
2009: Yi-Wen Huang; Rachel A Jansen; Enrica Fabbri; Dustin Potter; Sandya Liyanarachchi; Michael W Y Chan; Joseph C Liu; Anne P G Crijns; Robert Brown; Kenneth P Nephew; Ate G J van der Zee; David E Cohn; Pearlly S Yan; Hui-Ming (Tim) Huang; Huey-Jen L Lin
Identification of candidate epigenetic biomarkers for ovarian cancer detection.
Oncology reports 2009;22(4):853-61.
2009: Shuying Sun; Pearlly S Yan; Hui-Ming (Tim) Huang; Shili Lin
Identifying differentially methylated genes using mixed effect and generalized least square models.
BMC bioinformatics 2009;10():404.
2009: Yu-I Weng; Hui-Ming (Tim) Huang; Pearlly S Yan
Methylated DNA immunoprecipitation and microarray-based analysis: detection of DNA methylation in breast cancer cell lines.
Methods in molecular biology (Clifton, N.J.) 2009;590():165-76.
2009: Huaxia Qin; Michael W Y Chan; Sandya Liyanarachchi; Curtis Balch; Dustin Potter; Irene J Souriraj; Alfred S L Cheng; Francisco J Agosto-Perez; Elena V Nikonova; Pearlly S Yan; Huey-Jen Lin; Kenneth P Nephew; Joel Saltz; Louise C Showe; Hui-Ming (Tim) Huang; Ramana V Davuluri
An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules.
BMC systems biology 2009;3():73.
2009: Daniel E Deatherage; Dustin Potter; Pearlly S Yan; Hui-Ming (Tim) Huang; Shili Lin
Methylation analysis by microarray.
Methods in molecular biology (Clifton, N.J.) 2009;556():117-39.
2009: Pearlly S Yan; Dustin Potter; Daniel E Deatherage; Hui-Ming (Tim) Huang; Shili Lin
Differential methylation hybridization: profiling DNA methylation with a high-density CpG island microarray.
Methods in molecular biology (Clifton, N.J.) 2009;507():89-106.
2008: Michael Wy Chan; Yi-Wen Huang; Corinna Hartman-Frey; Chieh-Ti Kuo; Daniel Deatherage; Huaxia Qin; Alfred S L Cheng; Pearlly S Yan; Ramana V Davuluri; Hui-Ming (Tim) Huang; Kenneth P Nephew; Huey-Jen L Lin
Aberrant transforming growth factor beta1 signaling and SMAD4 nuclear translocation confer epigenetic repression of ADAM19 in ovarian cancer.
Neoplasia (New York, N.Y.) 2008;10(9):908-19.
2008: Benjamin A T Rodriguez; Alfred S L Cheng; Pearlly S Yan; Dustin Potter; Francisco J Agosto-Perez; Charles L Shapiro; Hui-Ming (Tim) Huang
Epigenetic repression of the estrogen-regulated Homeobox B13 gene in breast cancer.
Carcinogenesis 2008;29(7):1459-65.
2008: Shu Zhang; Curt Balch; Michael W Chan; Hung-Cheng Lai; Daniela Matei; Jeanne M Schilder; Pearlly S Yan; Hui-Ming (Tim) Huang; Kenneth P Nephew
Identification and characterization of ovarian cancer-initiating cells from primary human tumors.
Cancer research 2008;68(11):4311-20.
2008: Alfred S L Cheng; Aedín C Culhane; Michael W Y Chan; Chinnambally R Venkataramu; Mathias Ehrich; Aejaz Nasir; Benjamin A T Rodriguez; Joseph Liu; Pearlly S Yan; John Quackenbush; Kenneth P Nephew; Timothy J Yeatman; Hui-Ming (Tim) Huang
Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome.
Cancer research 2008;68(6):1786-96.
2008: Marcos R H Estécio; Pearlly S Yan; Hui-Ming (Tim) Huang; Jean-Pierre J Issa
Methylated CpG Island Amplification and Microarray (MCAM) for High-Throughput Analysis of DNA Methylation.
CSH protocols 2008;2008():pdb.prot4974.
2008: Junghee Han; Dustin Potter; Tahsin Kurc; Greg Singer; Pearlly S Yan; Sun Hao; Shannon Hastings; Stephen Langella; Scott Oster; Ramana V Davuluri; Hui-Ming (Tim) Huang; Joel Saltz
An application of a service-oriented system to support array annotation in custom chip design for epigenomic analysis.
Cancer informatics 2008;6():111-25.
2007: Marcos R H Estécio; Pearlly S Yan; Ashraf E K Ibrahim; Carmen Tellez; Lanlan Shen; Hui-Ming (Tim) Huang; Jean-Pierre J Issa
High-throughput methylation profiling by MCA coupled to CpG island microarray.
Genome research 2007;17(10):1529-36.
2007: Israel Zighelboim; Paul J Goodfellow; Amy P Schmidt; Ken C Walls; Mary Ann Mallon; David G Mutch; Pearlly S Yan; Hui-Ming (Tim) Huang; Matthew A Powell
Differential methylation hybridization array of endometrial cancers reveals two novel cancer-specific methylation markers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(10):2882-9.
2007: Marcos R H Estécio; Vazganush Gharibyan; Lanlan Shen; Ashraf E K Ibrahim; Ketan Doshi; Rong He; Jaroslav Jelinek; Allen S Yang; Pearlly S Yan; Hui-Ming (Tim) Huang; Eloiza H Tajara; Jean-Pierre J Issa
LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability.
PloS one 2007;2(5):e399.
2006: Meiyun Fan; Pearlly S Yan; Cori Hartman-Frey; Lei Chen; Henry Paik; Samuel L Oyer; Jonathan D Salisbury; Alfred S L Cheng; Lang Li; Phillip H Abbosh; Hui-Ming (Tim) Huang; Kenneth P Nephew
Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant.
Cancer research 2006;66(24):11954-66.
2006: Pearlly S Yan; Chinnambally Venkataramu; Ashraf Ibrahim; Joseph C Liu; Rulong Z Shen; Nils M Diaz; Barbara A Centeno; Frank Weber; Yu-Wei Leu; Charles L Shapiro; Charis Eng; Timothy J Yeatman; Hui-Ming (Tim) Huang
Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(22):6626-36.
2006: Jörg Felsberg; Pearlly S Yan; Hui-Ming (Tim) Huang; U Milde; Johannes Schramm; Otmar D Wiestler; Guido Reifenberger; Torsten Pietsch; Andreas Waha
DNA methylation and allelic losses on chromosome arm 14q in oligodendroglial tumours.
Neuropathology and applied neurobiology 2006;32(5):517-24.
2006: Kristin M Beima; Michael M Miazgowicz; Megan D Lewis; Pearlly S Yan; Hui-Ming (Tim) Huang; Amy S Weinmann
T-bet binding to newly identified target gene promoters is cell type-independent but results in variable context-dependent functional effects.
The Journal of biological chemistry 2006;281(17):11992-2000.
2006: Alfred S L Cheng; Victor X Jin; Meiyun Fan; Laura T Smith; Sandya Liyanarachchi; Pearlly S Yan; Yu-Wei Leu; Michael W Y Chan; Christoph Plass; Kenneth P Nephew; Ramana V Davuluri; Hui-Ming (Tim) Huang
Combinatorial analysis of transcription factor partners reveals recruitment of c-MYC to estrogen receptor-alpha responsive promoters.
Molecular cell 2006;21(3):393-404.
2005: Michael W Y Chan; Susan Wei; Ping Wen; Zailong Wang; Daniela Matei; Joseph C Liu; Sandya Liyanarachchi; Robert Brown; Kenneth P Nephew; Pearlly S Yan; Hui-Ming (Tim) Huang
Hypermethylation of 18S and 28S ribosomal DNAs predicts progression-free survival in patients with ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(20):7376-83.
2005: Remco van Doorn; Willem H Zoutman; Remco Dijkman; Renée X de Menezes; Suzan Commandeur; Aat A Mulder; Pieter A van der Velden; Maarten H Vermeer; Rein Willemze; Pearlly S Yan; Hui-Ming (Tim) Huang; Cornelis P Tensen
Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(17):3886-96.
2005: Andreas Waha; Stefanie Güntner; Hui-Ming (Tim) Huang; Pearlly S Yan; Bülent Arslan; Torsten Pietsch; Otmar D Wiestler; Andreas Waha
Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas.
Neoplasia (New York, N.Y.) 2005;7(3):193-9.
2004: Yu-Wei Leu; Pearlly S Yan; Meiyun Fan; Victor X Jin; Joseph C Liu; Edward M Curran; Wade V Welshons; Susan Wei; Ramana V Davuluri; Christoph Plass; Kenneth P Nephew; Hui-Ming (Tim) Huang
Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer.
Cancer research 2004;64(22):8184-92.
2004: Yutaka Kondo; Lanlan Shen; Pearlly S Yan; Hui-Ming (Tim) Huang; Jean-Pierre J Issa
Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(19):7398-403.
2004: Pearlly S Yan; Susan Wei; Hui-Ming (Tim) Huang
Methylation-specific oligonucleotide microarray.
Methods in molecular biology (Clifton, N.J.) 2004;287():251-60.
2003: Pearlly S Yan; Huidong Shi; Farahnaz Rahmatpanah; Timothy H-C Hsiau; Andrew H-A Hsiau; Yu-Wei Leu; Joseph C Liu; Hui-Ming (Tim) Huang
Differential distribution of DNA methylation within the RASSF1A CpG island in breast cancer.
Cancer research 2003;63(19):6178-86.
2003: Yu-Wei Leu; Farahnaz Rahmatpanah; Huidong Shi; Susan Wei; Joseph C Liu; Pearlly S Yan; Hui-Ming (Tim) Huang
Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation.
Cancer research 2003;63(19):6110-5.
2003: Chuan-Mu Chen; Hsiao-Ling Chen; Timothy H-C Hsiau; Andrew H-A Hsiau; Huidong Shi; Graham J R Brock; Susan Wei; Charles Caldwell; Pearlly S Yan; Hui-Ming (Tim) Huang
Methylation target array for rapid analysis of CpG island hypermethylation in multiple tissue genomes.
The American journal of pathology 2003;163(1):37-45.
2003: Daniel Y L Mao; John D Watson; Pearlly S Yan; Dalia Barsyte-Lovejoy; Fereshteh Khosravi; W Wei-Lynn Wong; Peggy J Farnham; Hui-Ming (Tim) Huang; Linda Z Penn
Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression.
Current biology : CB 2003;13(10):882-6.
2003: Huidong Shi; Susan Wei; Yu-Wei Leu; Farahnaz Rahmatpanah; Joseph C Liu; Pearlly S Yan; Kenneth P Nephew; Hui-Ming (Tim) Huang
Triple analysis of the cancer epigenome: an integrated microarray system for assessing gene expression, DNA methylation, and histone acetylation.
Cancer research 2003;63(9):2164-71.
2003: Julie Wells; Pearlly S Yan; Meredith Cechvala; Hui-Ming (Tim) Huang; Peggy J Farnham
Identification of novel pRb binding sites using CpG microarrays suggests that E2F recruits pRb to specific genomic sites during S phase.
Oncogene 2003;22(10):1445-60.
2003: Huidong Shi; Sabine Maier; Inko Nimmrich; Pearlly S Yan; Charles Caldwell; Alexander Olek; Hui-Ming (Tim) Huang
Oligonucleotide-based microarray for DNA methylation analysis: principles and applications.
Journal of cellular biochemistry 2003;88(1):138-43.
2002: Pearlly S Yan; Chuan-Mu Chen; Huidong Shi; Farahnaz Rahmatpanah; Susan Wei; Hui-Ming (Tim) Huang
Applications of CpG island microarrays for high-throughput analysis of DNA methylation.
The Journal of nutrition 2002;132(8 Suppl):2430S-2434S.
2002: Susan Wei; Chuan-Mu Chen; Gordon Strathdee; Jaturon Harnsomburana; Chi-Ren Shyu; Farahnaz Rahmatpanah; Huidong Shi; Shu-Wing Ng; Pearlly S Yan; Kenneth P Nephew; Robert Brown; Hui-Ming (Tim) Huang
Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2246-52.
2002: Pearlly S Yan; Thomas Efferth; Hsiao-Ling Chen; Jeffrey Lin; Franz Rödel; Laszlo Fuzesi; Hui-Ming (Tim) Huang
Use of CpG island microarrays to identify colorectal tumors with a high degree of concurrent methylation.
Methods (San Diego, Calif.) 2002;27(2):162-9.
2002: Huidong Shi; Pearlly S Yan; Chuan-Mu Chen; Farahnaz Rahmatpanah; Catherine Lofton-Day; Charles Caldwell; Hui-Ming (Tim) Huang
Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells.
Cancer research 2002;62(11):3214-20.
2002: Amy S Weinmann; Pearlly S Yan; Matthew J Oberley; Hui-Ming (Tim) Huang; Peggy J Farnham
Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis.
Genes & development 2002;16(2):235-44.
2002: Pearlly S Yan; Susan Wei; Hui-Ming (Tim) Huang
Differential methylation hybridization using CpG island arrays.
Methods in molecular biology (Clifton, N.J.) 2002;200():87-100.
2002: Raad S Gitan; Huidong Shi; Chuan-Mu Chen; Pearlly S Yan; Hui-Ming (Tim) Huang
Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis.
Genome research 2002;12(1):158-64.
2001: Pearlly S Yan; Chuan-Mu Chen; Huidong Shi; Farahnaz Rahmatpanah; Susan Wei; Charles Caldwell; Hui-Ming (Tim) Huang
Dissecting complex epigenetic alterations in breast cancer using CpG island microarrays.
Cancer research 2001;61(23):8375-80.
2000: Pearlly S Yan; MR Perry; Douglas Laux; Adam L Asare; Charles Caldwell; Hui-Ming (Tim) Huang
CpG island arrays: an application toward deciphering epigenetic signatures of breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(4):1432-8.
2000: Pearlly S Yan; F J Rodriguez; Douglas Laux; MR Perry; S B Standiford; Hui-Ming (Tim) Huang
Hypermethylation of ribosomal DNA in human breast carcinoma.
British journal of cancer 2000;82(3):514-7.
1999: Pearlly S Yan
Cholesterol oxidation products. Their occurrence and detection in our foodstuffs.
Advances in experimental medicine and biology 1999;459():79-98.