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Nobuyuki Yanagihara

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Noriaki Satoh; Kojiro Takahashi; Yumiko Toyohira; Masato Tsutsui; Susumu Ueno; Hideaki Itoh; Han Zhang; Nobuyuki Yanagihara
Stimulation of norepinephrine transporter function by fasudil, a Rho kinase inhibitor, in cultured bovine adrenal medullary cells.
Yumi Furuno; Hironori Miyata; Naoya Morisada; Tsuyoshi Morishita; Katsuhiko Noguchi; Yutaka Otsuji; Mayuko Sakanashi; Yasuyuki Sasaguri; Hiroaki Shimokawa; Kazunari Sugita; Masahito Tamura; Akihide Tanimoto; Yumiko Toyohira; Susumu Ueno; Sohsuke Yamada; Nobuyuki Yanagihara; Masato Tsutsui
Crucial vasculoprotective role of the whole nitric oxide synthase system in vascular lesion formation in mice: Involvement of bone marrow-derived cells.
Shingo Kakeda; Yukunori Korogi; Junji Moriya; Norihiro Ohnari; Toru Sato; Susumu Ueno; Nobuyuki Yanagihara; Masafumi Harada; Tsuyoshi Matsuda
Influence of work shift on glutamic acid and gamma-aminobutyric acid (GABA): evaluation with proton magnetic resonance spectroscopy at 3T.

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2012: Noriaki Satoh; Kojiro Takahashi; Yumiko Toyohira; Masato Tsutsui; Susumu Ueno; Hideaki Itoh; Han Zhang; Nobuyuki Yanagihara
Stimulation of norepinephrine transporter function by fasudil, a Rho kinase inhibitor, in cultured bovine adrenal medullary cells.
Naunyn-Schmiedeberg's archives of pharmacology 2012;385(9):921-31.
2011: Yumi Furuno; Hironori Miyata; Naoya Morisada; Tsuyoshi Morishita; Katsuhiko Noguchi; Yutaka Otsuji; Mayuko Sakanashi; Yasuyuki Sasaguri; Hiroaki Shimokawa; Kazunari Sugita; Masahito Tamura; Akihide Tanimoto; Yumiko Toyohira; Susumu Ueno; Sohsuke Yamada; Nobuyuki Yanagihara; Masato Tsutsui
Crucial vasculoprotective role of the whole nitric oxide synthase system in vascular lesion formation in mice: Involvement of bone marrow-derived cells.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2011;25(3):350-9.
2011: Shingo Kakeda; Yukunori Korogi; Junji Moriya; Norihiro Ohnari; Toru Sato; Susumu Ueno; Nobuyuki Yanagihara; Masafumi Harada; Tsuyoshi Matsuda
Influence of work shift on glutamic acid and gamma-aminobutyric acid (GABA): evaluation with proton magnetic resonance spectroscopy at 3T.
Psychiatry research 2011;192(1):55-9.
2011: Qing Dong; Tsutomu Sugiura; Yumiko Toyohira; Yasuhiro Yoshida; Nobuyuki Yanagihara; Yuji Karasaki
Stimulation of IFN-γ production by garlic lectin in mouse spleen cells: involvement of IL-12 via activation of p38 MAPK and ERK in macrophages.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2011;18(4):309-16.
2010: Kiyoko Shibata; Yasuko Yatera; Yumi Furuno; Ken Sabanai; Naoya Morisada; Sei Nakata; Tsuyoshi Morishita; Fumio Yamazaki; Akihide Tanimoto; Yasuyuki Sasaguri; Hiromi Tasaki; Yasuhide Nakashima; Hiroaki Shimokawa; Nobuyuki Yanagihara; Yutaka Otsuji; Masato Tsutsui
Spontaneous development of left ventricular hypertrophy and diastolic dysfunction in mice lacking all nitric oxide synthases.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(12):2681-92.
2010: Hideaki Itoh; Yumiko Toyohira; Susumu Ueno; Satoru Saeki; Han Zhang; Yumi Furuno; Kojiro Takahashi; Masato Tsutsui; Kenji Hachisuka; Nobuyuki Yanagihara
Upregulation of norepinephrine transporter function by prolonged exposure to nicotine in cultured bovine adrenal medullary cells.
Naunyn-Schmiedeberg's archives of pharmacology 2010;382(3):235-43.
2010: Yasuko Yatera; Kiyoko Shibata; Yumi Furuno; Ken Sabanai; Naoya Morisada; Sei Nakata; Tsuyoshi Morishita; Yumiko Toyohira; Ke-Yong Wang; Akihide Tanimoto; Yasuyuki Sasaguri; Hiromi Tasaki; Yasuhide Nakashima; Hiroaki Shimokawa; Nobuyuki Yanagihara; Yutaka Otsuji; Masato Tsutsui
Severe dyslipidaemia, atherosclerosis, and sudden cardiac death in mice lacking all NO synthases fed a high-fat diet.
Cardiovascular research 2010;87(4):675-82.
2010: Han Zhang; Yumiko Toyohira; Susumu Ueno; Yuko Shinohara; Hideaki Itoh; Yumi Furuno; Tohru Yamakuni; Masato Tsutsui; Kojiro Takahashi; Nobuyuki Yanagihara
Dual effects of nobiletin, a citrus polymethoxy flavone, on catecholamine secretion in cultured bovine adrenal medullary cells.
Journal of neurochemistry 2010;114(4):1030-8.
2010: Yumiko Toyohira; Susumu Ueno; Masato Tsutsui; Hideaki Itoh; Norio Sakai; Naoaki Saito; Kojiro Takahashi; Nobuyuki Yanagihara
Stimulatory effects of the soy phytoestrogen genistein on noradrenaline transporter and serotonin transporter activity.
Molecular nutrition & food research 2010;54(4):516-24.
2010: Kazunari Sugita; Kenji Kabashima; Ryutaro Yoshiki; Atsuko Ikenouchi-Sugita; Masato Tsutsui; Jun Nakamura; Nobuyuki Yanagihara; Yoshiki Tokura
Inducible nitric oxide synthase downmodulates contact hypersensitivity by suppressing dendritic cell migration and survival.
The Journal of investigative dermatology 2010;130(2):464-71.
2010: Naoya Morisada; Masayoshi Nomura; Hisae Nishii; Yumi Furuno; Mayuko Sakanashi; Ken Sabanai; Yumiko Toyohira; Susumu Ueno; Seiji Watanabe; Masahito Tamura; Tetsuro Matsumoto; Akihide Tanimoto; Yasuyuki Sasaguri; Hiroaki Shimokawa; Koichi Kusuhara; Nobuyuki Yanagihara; Akira Shirahata; Masato Tsutsui
Complete disruption of all nitric oxide synthase genes causes markedly accelerated renal lesion formation following unilateral ureteral obstruction in mice in vivo.
Journal of pharmacological sciences 2010;114(4):379-89.
2009: Atsuko Ikenouchi-Sugita; Yumiko Toyohira; Reiji Yoshimura; Susumu Ueno; Masato Tsutsui; Jun Nakamura; Nobuyuki Yanagihara
Opposite effects of milnacipran, a serotonin norepinephrine reuptake inhibitor, on the levels of nitric oxide and brain-derived neurotrophic factor in mouse brain cortex.
Naunyn-Schmiedeberg's archives of pharmacology 2009;380(6):479-86.
2009: Ken Sabanai; Masato Tsutsui; Akinori Sakai; Toshitaka Nakamura; Hiroaki Shimokawa; Nobuyuki Yanagihara
[Biochemical markers of bone turnover. New aspect. Nitric oxide synthase and bone metabolism].
Clinical calcium 2009;19(8):1133-41.
2009: Masato Tsutsui; Hiroaki Shimokawa; Yutaka Otsuji; Yoichi Ueta; Yasuyuki Sasaguri; Nobuyuki Yanagihara
Nitric oxide synthases and cardiovascular diseases: insights from genetically modified mice.
Circulation journal : official journal of the Japanese Circulation Society 2009;73(6):986-93.
2008: Masato Tsutsui; Sei Nakata; Hiroaki Shimokawa; Yutaka Otsuji; Nobuyuki Yanagihara
Spontaneous myocardial infarction and nitric oxide synthase.
Trends in cardiovascular medicine 2008;18(8):275-9.
2008: Taeko Matsuda; Yumiko Toyohira; Susumu Ueno; Masato Tsutsui; Nobuyuki Yanagihara
Simvastatin inhibits catecholamine secretion and synthesis induced by acetylcholine via blocking Na+ and Ca2+ influx in bovine adrenal medullary cells.
The Journal of pharmacology and experimental therapeutics 2008;327(1):130-6.
2008: Hiroaki Nii; Masato Tsutsui; Jun Kondo; Yumiko Toyohira; Susumu Ueno; Nobuyuki Yanagihara
Copper, zinc-superoxide dismutase enhances the mutagenicity in Salmonella typhimurium induced by 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole.
Mutation research 2008;653(1-2):14-22.
2008: Ken Sabanai; Masato Tsutsui; Akinori Sakai; Hideyuki Hirasawa; Shinya Tanaka; Eiichiro Nakamura; Akihide Tanimoto; Yasuyuki Sasaguri; Masako Ito; Hiroaki Shimokawa; Toshitaka Nakamura; Nobuyuki Yanagihara
Genetic disruption of all NO synthase isoforms enhances BMD and bone turnover in mice in vivo: involvement of the renin-angiotensin system.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2008;23(5):633-43.
2008: Sei Nakata; Masato Tsutsui; Hiroaki Shimokawa; Osamu Suda; Tsuyoshi Morishita; Kiyoko Shibata; Yasuko Yatera; Ken Sabanai; Akihide Tanimoto; Machiko Nagasaki; Hiromi Tasaki; Yasuyuki Sasaguri; Yasuhide Nakashima; Yutaka Otsuji; Nobuyuki Yanagihara
Spontaneous myocardial infarction in mice lacking all nitric oxide synthase isoforms.
Circulation 2008;117(17):2211-23.
2008: Tatsuo Nagata; Susumu Ueno; Hirofumi Morita; Toshiaki Kubota; Yumiko Toyohira; Masato Tsutsui; Akihiko Tawara; Nobuyuki Yanagihara
Direct inhibition of N-methyl-D-aspartate (NMDA)-receptor function by antiglaucomatous beta-antagonists.
Journal of pharmacological sciences 2008;106(3):423-34.
2008: Nobuyuki Yanagihara; Yumiko Toyohira; Yuko Shinohara
Insights into the pharmacological potential of estrogens and phytoestrogens on catecholamine signaling.
Annals of the New York Academy of Sciences 2008;1129():96-104.
2007: Yuko Shinohara; Yumiko Toyohira; Susumu Ueno; Minhui Liu; Masato Tsutsui; Nobuyuki Yanagihara
Effects of resveratrol, a grape polyphenol, on catecholamine secretion and synthesis in cultured bovine adrenal medullary cells.
Biochemical pharmacology 2007;74(11):1608-18.
2007: Minhui Liu; Nobuyuki Yanagihara; Yumiko Toyohira; Masato Tsutsui; Susume Ueno; Yuko Shinohara
Dual effects of daidzein, a soy isoflavone, on catecholamine synthesis and secretion in cultured bovine adrenal medullary cells.
Endocrinology 2007;148(11):5348-54.
2007: Masato Tsutsui; Hiroaki Shimokawa; Tsuyoshi Morishita; Sei Nakata; Ken Sabanai; Yasuhide Nakashima; Nobuyuki Yanagihara
[Development of genetically engineered mice lacking all three nitric oxide synthase isoforms].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2007;127(9):1347-55.
2007: Koji Shinkai; Yumiko Toyohira; Reiji Yoshimura; Masato Tsutsui; Susume Ueno; Jun Nakamura; Nobuyuki Yanagihara
Stimulation of catecholamine synthesis via activation of p44/42 MAPK in cultured bovine adrenal medullary cells by milnacipran.
Naunyn-Schmiedeberg's archives of pharmacology 2007;375(1):65-72.
2007: Susumu Ueno; Yasuhiro Yoshida; Yukiko Fueta; Toru Ishidao; Jiqin Liu; Naoki Kunugita; Nobuyuki Yanagihara; Hajime Hori
Changes in the function of the inhibitory neurotransmitter system in the rat brain following subchronic inhalation exposure to 1-bromopropane.
Neurotoxicology 2007;28(2):415-20.
2007: Sei Nakata; Masato Tsutsui; Hiroaki Shimokawa; Takahiro Yamashita; Akihide Tanimoto; Hiromi Tasaki; Kiyoshi Ozumi; Ken Sabanai; Tsuyoshi Morishita; Osamu Suda; Hideyasu Hirano; Yasuyuki Sasaguri; Yasuhide Nakashima; Nobuyuki Yanagihara
Statin treatment upregulates vascular neuronal nitric oxide synthase through Akt/NF-kappaB pathway.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(1):92-8.
2006: Kojiro Takahashi; Yumiko Toyohira; Susumu Ueno; Masato Tsutsui; Nobuyuki Yanagihara
Capsaicin inhibits catecholamine secretion and synthesis by blocking Na+ and Ca2+ influx through a vanilloid receptor-independent pathway in bovine adrenal medullary cells.
Naunyn-Schmiedeberg's archives of pharmacology 2006;374(2):107-16.
2006: Masato Tsutsui; Hiroaki Shimokawa; Tsuyoshi Morishita; Yasuhide Nakashima; Nobuyuki Yanagihara
Development of genetically engineered mice lacking all three nitric oxide synthases.
Journal of pharmacological sciences 2006;102(2):147-54.
2006: Osamu Suda; Masato Tsutsui; Tsuyoshi Morishita; Masataka Horiuchi; Sei Nakata; Ryouji Kouzuma; Masahiro Okazaki; Akiko Sumiyama-Fujinishi; Tsunetaka Mizuki; Nobuyuki Yanagihara; Hiromi Tasaki; Yasuhide Nakashima
Long-term treatment with imidapril but not with nifedipine enhances plasma NOx concentration in patients with essential hypertension.
Journal of pharmacological sciences 2006;101(2):159-65.
2006: Soichiro Akasaka; Masayoshi Nomura; Hisae Nishii; Naohiro Fujimoto; Yoichi Ueta; Masato Tsutsui; Hiroaki Shimokawa; Nobuyuki Yanagihara; Tetsuro Matsumoto
The hypothalamo-pituitary axis responses to lipopolysaccharide-induced endotoxemia in mice lacking inducible nitric oxide synthase.
Brain research 2006;1089(1):1-9.
2006: Nobuyuki Yanagihara; Minhui Liu; Yumiko Toyohira; Masato Tsutsui; Susumu Ueno; Yuko Shinohara; Kojiro Takahashi; Kazumi Tanaka
Stimulation of catecholamine synthesis through unique estrogen receptors in the bovine adrenomedullary plasma membrane by 17beta-estradiol.
Biochemical and biophysical research communications 2006;339(2):548-53.
2005: Sei Nakata; Masato Tsutsui; Hiroaki Shimokawa; Masahito Tamura; Hiromi Tasaki; Tsuyoshi Morishita; Osamu Suda; Susumu Ueno; Yumiko Toyohira; Yasuhide Nakashima; Nobuyuki Yanagihara
Vascular neuronal NO synthase is selectively upregulated by platelet-derived growth factor: involvement of the MEK/ERK pathway.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(12):2502-8.
2005: Koji Shinkai; Reiji Yoshimura; Yumiko Toyohira; Susumu Ueno; Masato Tsutsui; Jun Nakamura; Nobuyuki Yanagihara
Effect of prolonged exposure to milnacipran on norepinephrine transporter in cultured bovine adrenal medullary cells.
Biochemical pharmacology 2005;70(9):1389-97.
2005: Reiji Yoshimura; Koji Shinkai; Yumiko Toyohira; Susumu Ueno; Nobuyuki Yanagihara; Jun Nakamura
Effects of zotepine and olanzapine on noradrenaline transporter in cultured bovine adrenal medullary cells.
Human psychopharmacology 2005;20(7):477-84.
2005: Tsuyoshi Morishita; Masato Tsutsui; Hiroaki Shimokawa; Ken Sabanai; Hiromi Tasaki; Osamu Suda; Sei Nakata; Akihide Tanimoto; Ke-Yong Wang; Yoichi Ueta; Yasuyuki Sasaguri; Yasuhide Nakashima; Nobuyuki Yanagihara
Nephrogenic diabetes insipidus in mice lacking all nitric oxide synthase isoforms.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(30):10616-21.
2005: Masayoshi Nomura; Masato Tsutsui; Hiroaki Shimokawa; Naohiro Fujimoto; Yoichi Ueta; Tsuyoshi Morishita; Nobuyuki Yanagihara; Tetsuro Matsumoto
Effects of nitric oxide synthase isoform deletion on oxytocin and vasopressin messenger RNA in mouse hypothalamus.
Neuroreport 2005;16(4):413-7.
2005: Yumiko Toyohira; Tatsuhiko Kubo; Miyabi Watanabe; Yasuhito Uezono; Susumu Ueno; Koji Shinkai; Masato Tsutsui; Futoshi Izumi; Nobuyuki Yanagihara
Selective blockade of nicotinic acetylcholine receptors by pimobendan, a drug for the treatment of heart failure: reduction of catecholamine secretion and synthesis in adrenal medullary cells.
Naunyn-Schmiedeberg's archives of pharmacology 2005;371(2):107-13.
2005: Nobuyuki Yanagihara; Yumiko Toyohira; Susumu Ueno; Masato Tsutsui; Kensuke Utsunomiya; Minhui Liu; Kazumi Tanaka
Stimulation of catecholamine synthesis by environmental estrogenic pollutants.
Endocrinology 2005;146(1):265-72.
2004: Masato Tsutsui; Susumu Ueno; Yumiko Toyohira; Nobuyuki Yanagihara
[Expression and functions of inducible nitric oxide synthase].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 9():460-4.
2004: Osamu Suda; Masato Tsutsui; Tsuyoshi Morishita; Hiromi Tasaki; Susumu Ueno; Sei Nakata; Takashi Tsujimoto; Yumiko Toyohira; Yoshiaki Hayashida; Yasuyuki Sasaguri; Yoichi Ueta; Yasuhide Nakashima; Nobuyuki Yanagihara
Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: involvement of renin-angiotensin system and oxidative stress.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(9):1682-8.
2004: Susumu Ueno; Masato Tsutsui; Yumiko Toyohira; Kouichiro Minami; Nobuyuki Yanagihara
Sites of positive allosteric modulation by neurosteroids on ionotropic gamma-aminobutyric acid receptor subunits.
FEBS letters 2004;566(1-3):213-7.
2004: Masataka Horiuchi; Masato Tsutsui; Hiromi Tasaki; Tsuyoshi Morishita; Osamu Suda; Sei Nakata; Shun-ichi Nihei; Masaharu Miyamoto; Ryouji Kouzuma; Masahiro Okazaki; Nobuyuki Yanagihara; Tetsuo Adachi; Yasuhide Nakashima
Upregulation of vascular extracellular superoxide dismutase in patients with acute coronary syndromes.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(1):106-11.
2003: Yasusada Kawada; Susumu Ueno; Kohtaro Asayama; Masato Tsutsui; Kensuke Utsunomiya; Yumiko Toyohira; Naoya Morisada; Kazumi Tanaka; Akira Shirahata; Nobuyuki Yanagihara
Stimulation of catecholamine synthesis by orexin-A in bovine adrenal medullary cells through orexin receptor 1.
Biochemical pharmacology 2003;66(1):141-7.
2003: Yumiko Toyohira; Kensuke Utsunomiya; Susumu Ueno; Kouichiro Minami; Yasuhito Uezono; Reiji Yoshimura; Masato Tsutsui; Futoshi Izumi; Nobuyuki Yanagihara
Inhibition of the norepinephrine transporter function in cultured bovine adrenal medullary cells by bisphenol A.
Biochemical pharmacology 2003;65(12):2049-54.
2003: T Nagata; Nobuya Harayama; N Sasaki; Masumi Inoue; Kazumi Tanaka; Yumiko Toyohira; Yasuhito Uezono; T Maruyama; Nobuyuki Yanagihara; Yoichi Ueta; Izumi Shibuya
Mechanisms of cytosolic Ca2+ suppression by prostaglandin E2 receptors in rat melanotrophs.
Journal of neuroendocrinology 2003;15(1):33-41.
2002: Takafumi Horishita; Kouichiro Minami; Nobuyuki Yanagihara; Munehiro Shiraishi; Takashi Okamoto; Yousuke Shiga; Susumu Ueno; Akio Shigematsu
Alphaxalone, a neurosteroid anesthetic, inhibits norepinephrine transporter function in cultured bovine adrenal medullary cells.
Anesthesia and analgesia 2002;95(6):1661-6, table of contents.
2002: Tsuyoshi Morishita; Masato Tsutsui; Hiroaki Shimokawa; Masataka Horiuchi; Akihide Tanimoto; Osamu Suda; Hiromi Tasaki; Paul L Huang; Yasuyuki Sasaguri; Nobuyuki Yanagihara; Yasuhide Nakashima
Vasculoprotective roles of neuronal nitric oxide synthase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(14):1994-6.
2002: Izumi Shibuya; Kensuke Utsunomiya; Yumiko Toyohira; Susumu Ueno; Masato Tsutsui; Tat Beng Cheah; Yoichi Ueta; Futoshi Izumi; Nobuyuki Yanagihara
Regulation of catecholamine synthesis by leptin.
Annals of the New York Academy of Sciences 2002;971():522-7.
2002: Munehiro Shiraishi; Izumi Shibuya; Kouichiro Minami; Yasuhito Uezono; Takashi Okamoto; Nobuyuki Yanagihara; Susumu Ueno; Yoichi Ueta; Akio Shigematsu
A neurosteroid anesthetic, alphaxalone, inhibits nicotinic acetylcholine receptors in cultured bovine adrenal chromaffin cells.
Anesthesia and analgesia 2002;95(4):900-6, table of contents.
2002: Osamu Suda; Masato Tsutsui; Tsuyoshi Morishita; Akihide Tanimoto; Masataka Horiuchi; Hiromi Tasaki; Paul L Huang; Yasuyuki Sasaguri; Nobuyuki Yanagihara; Yasuhide Nakashima
Long-term treatment with N(omega)-nitro-L-arginine methyl ester causes arteriosclerotic coronary lesions in endothelial nitric oxide synthase-deficient mice.
Circulation 2002;106(13):1729-35.
2002: Koji Kajiwara; Toshihiko Yanagita; Yasuhide Nakashima; Akihiko Wada; Futoshi Izumi; Nobuyuki Yanagihara
Differential effects of short and prolonged exposure to carvedilol on voltage-dependent Na(+) channels in cultured bovine adrenal medullary cells.
The Journal of pharmacology and experimental therapeutics 2002;302(1):212-8.
2002: Koji Hara; Kouichiro Minami; Susumu Ueno; Yumiko Toyohira; Masato Tsutsui; Akio Shigematsu; Nobuyuki Yanagihara
Up-regulation of noradrenaline transporter in response to prolonged exposure to ketamine.
Naunyn-Schmiedeberg's archives of pharmacology 2002;365(5):406-12.
2002: Munehiro Shiraishi; Kouichiro Minami; Yasuhito Uezono; Nobuyuki Yanagihara; Akio Shigematsu; Izumi Shibuya
Inhibitory effects of tramadol on nicotinic acetylcholine receptors in adrenal chromaffin cells and in Xenopus oocytes expressing alpha 7 receptors.
British journal of pharmacology 2002;136(2):207-16.
2002: Kenichiro Sagata; Kouichiro Minami; Nobuyuki Yanagihara; Munehiro Shiraishi; Yumiko Toyohira; Susumu Ueno; Akio Shigematsu
Tramadol inhibits norepinephrine transporter function at desipramine-binding sites in cultured bovine adrenal medullary cells.
Anesthesia and analgesia 2002;94(4):901-6, table of contents.
2002: Tsuyoshi Morishita; Masato Tsutsui; Hiroaki Shimokawa; Hiromi Tasaki; Osamu Suda; Kengo Kobayashi; Masataka Horiuchi; Haruhito Okuda; Yuki Tsuda; Nobuyuki Yanagihara; Yasuhide Nakashima
Long-term treatment with perindopril ameliorates dobutamine-induced myocardial ischemia in patients with coronary artery disease.
Japanese journal of pharmacology 2002;88(1):100-7.
2001: Munehiro Shiraishi; Kouichiro Minami; Yasuhito Uezono; Nobuyuki Yanagihara; Akio Shigematsu
Inhibition by tramadol of muscarinic receptor-induced responses in cultured adrenal medullary cells and in Xenopus laevis oocytes expressing cloned M1 receptors.
The Journal of pharmacology and experimental therapeutics 2001;299(1):255-60.
2001: Kensuke Utsunomiya; Nobuyuki Yanagihara; Eiichi Tachikawa; Tat Beng Cheah; K Kajiwara; Yumiko Toyohira; Susumu Ueno; Futoshi Izumi
Stimulation of catecholamine synthesis in cultured bovine adrenal medullary cells by leptin.
Journal of neurochemistry 2001;76(3):926-34.
2000: Koji Hara; Nobuyuki Yanagihara; Kouichiro Minami; H Hirano; Tetsutaro Sata; Akio Shigematsu; Futoshi Izumi
Dual effects of intravenous anesthetics on the function of norepinephrine transporters.
Anesthesiology 2000;93(5):1329-35.
2000: Kayo Uryu; Kouichiro Minami; Nobuyuki Yanagihara; Koji Hara; Yumiko Toyohira; Futoshi Izumi; Akio Shigematsu
Inhibition by neuromuscular blocking drugs of norepinephrine transporter in cultured bovine adrenal medullary cells.
Anesthesia and analgesia 2000;91(3):546-51.
2000: Nobuyuki Yanagihara; Kensuke Utsunomiya; Tat Beng Cheah; H Hirano; K Kajiwara; Koji Hara; E Nakamura; Yumiko Toyohira; Yasuhito Uezono; Susumu Ueno; Futoshi Izumi
Characterization and functional role of leptin receptor in bovine adrenal medullary cells.
Biochemical pharmacology 2000;59(9):1141-5.
2000: Reiji Yoshimura; Nobuyuki Yanagihara; K Hara; Takeshi Terao; Jun Nakamura; Susumu Ueno; Yumiko Toyohira; Yasuhito Uezono; S Kaneko; M Kawamura; K Abe; Futoshi Izumi
Inhibitory effects of clozapine and other antipsychotic drugs on noradrenaline transporter in cultured bovine adrenal medullary cells.
Psychopharmacology 2000;149(1):17-23.
1999: Izumi Shibuya; Kazumi Tanaka; Yasuhito Uezono; Yoichi Ueta; Yumiko Toyohira; Nobuyuki Yanagihara; Futoshi Izumi; Hiroshi Yamashita
Prostaglandin E2 induces Ca2+ release from ryanodine/caffeine-sensitive stores in bovine adrenal medullary cells via EP1-like receptors.
Journal of neurochemistry 1999;73(5):2167-74.
1999: K Kajiwara; Nobuyuki Yanagihara; Tatsuya Ioka; Masato Tsutsui; Akira Yashiro; Yumiko Toyohira; Yasuhide Nakashima; Futoshi Izumi
Modification of low density lipoprotein potentiates its inhibitory effect on catecholamine secretion in cultured bovine adrenal medullary cells.
Naunyn-Schmiedeberg's archives of pharmacology 1999;360(1):99-102.
1998: Reiji Yoshimura; Nobuyuki Yanagihara; Takeshi Terao; Yasuhito Uezono; Yumiko Toyohira; Susumu Ueno; K Abe; Futoshi Izumi
Carbamazepine-induced up-regulation of voltage-dependent Na+ channels in bovine adrenal medullary cells in culture.
The Journal of pharmacology and experimental therapeutics 1998;287(2):441-7.
1998: Nobuyuki Yanagihara; Yumiko Toyohira; Yasuhito Uezono; Susumu Ueno; Futoshi Izumi
[Signal transduction of intracellular Ca2+ in adrenal medullary chromaffin cells].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(12 Suppl):1777-83.
1998: Koji Hara; Nobuyuki Yanagihara; Kouichiro Minami; Susumu Ueno; Yumiko Toyohira; Tetsutaro Sata; M Kawamura; M Brüss; Heinz Bönisch; Akio Shigematsu; Futoshi Izumi
Ketamine interacts with the noradrenaline transporter at a site partly overlapping the desipramine binding site.
Naunyn-Schmiedeberg's archives of pharmacology 1998;358(3):328-33.
1998: K Kajiwara; Nobuyuki Yanagihara; Masato Tsutsui; Akira Yashiro; Hiromi Tasaki; Yasuhide Nakashima; Futoshi Izumi
Atherogenic lipoproteins inhibit catecholamine secretion in cultured bovine adrenal medullary cells.
Naunyn-Schmiedeberg's archives of pharmacology 1998;358(3):308-14.
1998: Kazumi Tanaka; Izumi Shibuya; Yasuhito Uezono; Yoichi Ueta; Yumiko Toyohira; Nobuyuki Yanagihara; Futoshi Izumi; T Kanno; Hiroshi Yamashita
Pituitary adenylate cyclase-activating polypeptide causes Ca2+ release from ryanodine/caffeine stores through a novel pathway independent of both inositol trisphosphates and cyclic AMP in bovine adrenal medullary cells.
Journal of neurochemistry 1998;70(4):1652-61.
1998: Yumiko Toyohira; Nobuyuki Yanagihara; Kouichiro Minami; Susumu Ueno; Yasuhito Uezono; Eiichi Tachikawa; Y Kondo; Takeshi Kashimoto; Futoshi Izumi
Down-regulation of the noradrenaline transporter by interferon-alpha in cultured bovine adrenal medullary cells.
Journal of neurochemistry 1998;70(4):1441-7.
1998: Yasuhito Uezono; M Akihara; Muneshige Kaibara; C Kawano; Izumi Shibuya; Y Ueda; Nobuyuki Yanagihara; Yumiko Toyohira; Hiroshi Yamashita; Kohtaro Taniyama; Futoshi Izumi
Activation of inwardly rectifying K+ channels by GABA-B receptors expressed in Xenopus oocytes.
Neuroreport 1998;9(4):583-7.
1998: Yasuhito Uezono; Izumi Shibuya; Y Ueda; Kazumi Tanaka; Yosuke Oishi; Nobuyuki Yanagihara; S Ueno; Yumiko Toyohira; Tetsuya Nakamura; Hiroshi Yamashita; Futoshi Izumi
Adrenomedullin increases intracellular Ca2+ and inositol 1,4,5-trisphosphate in human oligodendroglial cell line KG-1C.
Brain research 1998;786(1-2):230-4.
1998: Nobuyuki Yanagihara; Koji Hara; K Kajiwara; Kouichiro Minami; Yumiko Toyohira; Yasuhito Uezono; Susumu Ueno; H Hirano; U Yamashita; Futoshi Izumi
Stimulatory effect of lymphocyte-derived factor on catecholamine efflux from cultured bovine adrenal medullary cells.
Neuroscience letters 1998;243(1-3):25-8.
1998: Reiji Yoshimura; Nobuyuki Yanagihara; Takeshi Terao; Kouichiro Minami; Yumiko Toyohira; Susumu Ueno; Yasuhito Uezono; K Abe; Futoshi Izumi
An active metabolite of carbamazepine, carbamazepine-10,11-epoxide, inhibits ion channel-mediated catecholamine secretion in cultured bovine adrenal medullary cells.
Psychopharmacology 1998;135(4):368-73.
1998: Yosuke Oishi; Yasuhito Uezono; Nobuyuki Yanagihara; Futoshi Izumi; Tetsuya Nakamura; K Suzuki
Transmural compression-induced proliferation and DNA synthesis through activation of a tyrosine kinase pathway in rat astrocytoma RCR-1 cells.
Brain research 1998;781(1-2):159-66.
1998: Nobuyuki Yanagihara; Futoshi Izumi; E Miyamoto; M Oka
Factors affecting adrenal medullary catecholamine biosynthesis and release.
Advances in pharmacology (San Diego, Calif.) 1998;42():18-21.
1997: Yasuhito Uezono; Y Ueda; Susumu Ueno; Izumi Shibuya; Nobuyuki Yanagihara; Yumiko Toyohira; Hiroshi Yamashita; Futoshi Izumi
Enhancement by baclofen of the Gs-coupled receptor-mediated cAMP production in Xenopus oocytes expressing rat brain cortex poly (A)+ RNA: a role of G-protein beta gamma subunits.
Biochemical and biophysical research communications 1997;241(2):476-80.
1997: Eiichi Tachikawa; Y Kondo; M Takahashi; Takeshi Kashimoto; Nobuyuki Yanagihara; Yumiko Toyohira; Futoshi Izumi
Interferon-alpha reduces catecholamine secretion from bovine adrenal chromaffin cells stimulated by acetylcholine.
Naunyn-Schmiedeberg's archives of pharmacology 1997;356(6):699-705.
1997: S Yamamoto; Isao Morimoto; Nobuyuki Yanagihara; Kenji Kangawa; Kiyotoshi Inenaga; Sumiya Eto; Hiroshi Yamashita
C-type natriuretic peptide suppresses arginine-vasopressin secretion from dissociated magnocellular neurons in newborn rat supraoptic nucleus.
Neuroscience letters 1997;229(2):97-100.
1997: S Yamamoto; Isao Morimoto; Nobuyuki Yanagihara; Kazuya Zeki; Takashi Fujihira; Futoshi Izumi; Hiroshi Yamashita; Sumiya Eto
Parathyroid hormone-related peptide-(1-34) [PTHrP-(1-34)] induces vasopressin release from the rat supraoptic nucleus in vitro through a novel receptor distinct from a type I or type II PTH/PTHrP receptor.
Endocrinology 1997;138(5):2066-72.
1996: Kouichiro Minami; Nobuyuki Yanagihara; K Segawa; Tetsutaro Sata; Masato Tsutsui; Akio Shigematsu; Futoshi Izumi
Inhibition by protamine of catecholamine secretion and ion influxes in bovine adrenal medullary cells in culture.
The Journal of pharmacology and experimental therapeutics 1996;279(2):838-43.
1996: Nobuyuki Yanagihara; Y Oishi; H Yamamoto; Masato Tsutsui; J Kondoh; T Sugiura; E Miyamoto; Futoshi Izumi
Phosphorylation of chromogranin A and catecholamine secretion stimulated by elevation of intracellular Ca2+ in cultured bovine adrenal medullary cells.
The Journal of biological chemistry 1996;271(29):17463-8.
1996: Masato Tsutsui; Nobuyuki Yanagihara; K Fukunaga; Kouichiro Minami; Yasuhide Nakashima; A Kuroiwa; E Miyamoto; Futoshi Izumi
Ca(2+)/calmodulin-dependent protein kinase II inhibitor KN-62 inhibits adrenal medullary chromaffin cell functions independent of its action on the kinase.
Journal of neurochemistry 1996;66(6):2517-22.
1996: Kouichiro Minami; Nobuyuki Yanagihara; K Segawa; Masato Tsutsui; Akio Shigematsu; Futoshi Izumi
Inhibitory effects of propofol on catecholamine secretion and uptake in cultured bovine adrenal medullary cells.
Naunyn-Schmiedeberg's archives of pharmacology 1996;353(5):572-8.
1996: T Nagatomo; Izumi Shibuya; Narutoshi Kabashima; Nobuya Harayama; Yoichi Ueta; Yumiko Toyohira; Yasuhito Uezono; Nobuyuki Yanagihara; Futoshi Izumi; A Wada; H Yamashita
Proadrenomedullin N-terminal 20 peptide (PAMP) reduces inward currents and Ca2+ rises induced by nicotine in bovine adrenal medullary cells.
Life sciences 1996;59(20):1723-30.
1995: Reiji Yoshimura; Nobuyuki Yanagihara; Takeshi Terao; Kouichiro Minami; K Abe; Futoshi Izumi
Inhibition by carbamazepine of various ion channels-mediated catecholamine secretion in cultured bovine adrenal medullary cells.
Naunyn-Schmiedeberg's archives of pharmacology 1995;352(3):297-303.
1995: N Inokuchi; Kazuya Zeki; Isao Morimoto; Y Nakano; Takashi Fujihira; Uki Yamashita; Nobuyuki Yanagihara; Futoshi Izumi; Sumiya Eto
Stimulatory effect of interleukin-1 alpha on proliferation through a Ca2+/calmodulin-dependent pathway of a human thyroid carcinoma cell line, NIM 1.
Japanese journal of cancer research : Gann 1995;86(7):670-6.
1995: Eiichi Tachikawa; K Furumachi; Nobuyuki Yanagihara; Takeshi Kashimoto; S Takahashi; Futoshi Izumi
Effect of cAMP-dependent protein kinase on catecholamine secretion from bovine adrenal chromaffin cells.
Japanese journal of pharmacology 1995;67(2):101-6.
1994: Masato Tsutsui; Nobuyuki Yanagihara; E Miyamoto; A Kuroiwa; Futoshi Izumi
Correlation of activation of Ca2+/calmodulin-dependent protein kinase II with catecholamine secretion and tyrosine hydroxylase activation in cultured bovine adrenal medullary cells.
Molecular pharmacology 1994;46(6):1041-7.
1994: S Sashihara; Nobuyuki Yanagihara; Futoshi Izumi; Y Murai; Takashi Mita
Differential up-regulation of voltage-dependent Na+ channels induced by phenytoin in brains of genetically seizure-susceptible (E1) and control (ddY) mice.
Neuroscience 1994;62(3):803-11.
1994: Nobuyuki Yanagihara; Yumiko Toyohira; H Yamamoto; Y Ohta; Masato Tsutsui; E Miyamoto; Futoshi Izumi
Occurrence and activation of Ca2+/calmodulin-dependent protein kinase II and its endogenous substrates in bovine adrenal medullary cells.
Molecular pharmacology 1994;46(3):423-30.
1994: Y Nakano; Isao Morimoto; O Ishida; Takashi Fujihira; A Mizokami; A Tanimoto; Nobuyuki Yanagihara; Futoshi Izumi; Sumiya Eto
The receptor, metabolism and effects of androgen in osteoblastic MC3T3-E1 cells.
Bone and mineral 1994;26(3):245-59.
1994: H Kobayashi; S Ueno; Masato Tsutsui; M Okazaki; Yasuhito Uezono; Nobuyuki Yanagihara; T Yuhi; Futoshi Izumi
C-type natriuretic peptide increases cyclic GMP in rat cerebral microvessels in primary culture.
Brain research 1994;648(2):324-6.
1994: Kouichiro Minami; Nobuyuki Yanagihara; Yumiko Toyohira; Masato Tsutsui; Akio Shigematsu; A Wada; Futoshi Izumi
Isoflurane inhibits nicotinic acetylcholine receptor-mediated 22Na+ influx and muscarinic receptor-evoked cyclic GMP production in cultured bovine adrenal medullary cells.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(3):223-9.
1994: Masato Tsutsui; Nobuyuki Yanagihara; Kouichiro Minami; H Kobayashi; Yasuhide Nakashima; A Kuroiwa; Futoshi Izumi
C-type natriuretic peptide stimulates catecholamine synthesis through the accumulation of cyclic GMP in cultured bovine adrenal medullary cells.
The Journal of pharmacology and experimental therapeutics 1994;268(2):584-9.
1994: Nobuyuki Yanagihara; Kouichiro Minami; F Shirakawa; Yasuhito Uezono; H Kobayashi; Sumiya Eto; Futoshi Izumi
Stimulatory effect of IL-1 beta on catecholamine secretion from cultured bovine adrenal medullary cells.
Biochemical and biophysical research communications 1994;198(1):81-7.
1993: H Kobayashi; T Mizuki; Masato Tsutsui; K Minami; Nobuyuki Yanagihara; T Yuhi; Futoshi Izumi
Receptors for C-type natriuretic peptide in cultured rat glial cells.
Brain research 1993;617(1):163-6.
1993: S Sashihara; Nobuyuki Yanagihara; Futoshi Izumi; Takashi Mita
The effect of phenytoin on voltage-dependent Na+ channels in epileptic El mice.
The Japanese journal of psychiatry and neurology 1993;47(2):369-70.
1992: A Wada; Yasuhito Uezono; M Arita; T Yuhi; H Kobayashi; Nobuyuki Yanagihara; Futoshi Izumi
Cooperative modulation of voltage-dependent sodium channels by brevetoxin and classical neurotoxins in cultured bovine adrenal medullary cells.
The Journal of pharmacology and experimental therapeutics 1992;263(3):1347-51.
1992: Yasuhito Uezono; A Wada; Nobuyuki Yanagihara; H Kobayashi; T Mizuki; Takeshi Terao; Y Koda; Futoshi Izumi
Veratridine causes the Ca(2+)-dependent increase in diacylglycerol formation and translocation of protein kinase C to membranes in cultured bovine adrenal medullary cells.
Naunyn-Schmiedeberg's archives of pharmacology 1992;346(1):76-81.
1992: Takeshi Terao; Nobuyuki Yanagihara; K Abe; Futoshi Izumi
Lithium chloride stimulates catecholamine synthesis and secretion in cultured bovine adrenal medullary cells.
Biological psychiatry 1992;31(10):1038-49.
1992: S Sashihara; Nobuyuki Yanagihara; H Kobayashi; Futoshi Izumi; S Tsuji; Y Murai; Takashi Mita
Overproduction of voltage-dependent Na+ channels in the developing brain of genetically seizure-susceptible E1 mice.
Neuroscience 1992;48(2):285-91.
1991: Nobuyuki Yanagihara; M Okazaki; Takeshi Terao; Yasuhito Uezono; A Wada; Futoshi Izumi
Stimulatory effects of brain natriuretic peptide on cyclic GMP accumulation and tyrosine hydroxylase activity in cultured bovine adrenal medullary cells.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(3):289-95.
1991: Nobuyuki Yanagihara; Yumiko Toyohira; Y Koda; A Wada; Futoshi Izumi
Inhibitory effect of okadaic acid on carbachol-evoked secretion of catecholamines in cultured bovine adrenal medullary cells.
Biochemical and biophysical research communications 1991;174(1):77-83.
1991: Nobuyuki Yanagihara; Eiichi Tachikawa; Futoshi Izumi; S Yasugawa; H Yamamoto; E Miyamoto
Staurosporine: an effective inhibitor for Ca2+/calmodulin-dependent protein kinase II.
Journal of neurochemistry 1991;56(1):294-8.
1990: Y Koda; H Kobayashi; T Mizuki; M Okazaki; Yasuhito Uezono; Nobuyuki Yanagihara; A Wada; Futoshi Izumi
Protein kinase C subtypes in tissues derived from neural crest.
Brain research 1990;518(1-2):334-6.
1990: Nobuyuki Yanagihara; K Yokota; H Kobayashi; A Wada; Yasuhito Uezono; Futoshi Izumi
Sodium/proton exchange in cultured bovine adrenal medullary cells.
Journal of neurochemistry 1990;54(5):1626-31.
1989: Yasuhito Uezono; Nobuyuki Yanagihara; A Wada; Y Koda; K Yokota; H Kobayashi; Futoshi Izumi
Veratridine-induced phosphorylation and activation of tyrosine hydroxylase, and synthesis of catecholamines in cultured bovine adrenal medullary cells.
Naunyn-Schmiedeberg's archives of pharmacology 1989;339(6):653-9.
1989: A Wada; Yasuhito Uezono; M Arita; K Tsuji; Nobuyuki Yanagihara; H Kobayashi; Futoshi Izumi
High-affinity and selectivity of neosurugatoxin for the inhibition of 22Na influx via nicotinic receptor-ion channel in cultured bovine adrenal medullary cells: comparative study with histrionicotoxin.
Neuroscience 1989;33(2):333-9.
1989: Y Koda; A Wada; Nobuyuki Yanagihara; Yasuhito Uezono; Futoshi Izumi
cis-unsaturated fatty acids stimulate catecholamine secretion, tyrosine hydroxylase and protein kinase C in adrenal medullary cells.
Neuroscience 1989;29(2):495-502.
1989: M Okazaki; Nobuyuki Yanagihara; Futoshi Izumi; Yasuhide Nakashima; A Kuroiwa
Carbachol-induced cosecretion of immunoreactive atrial natriuretic peptides with catecholamines from cultured bovine adrenal medullary cells.
Journal of neurochemistry 1989;52(1):222-8.
1988: K Yokota; Nobuyuki Yanagihara; Futoshi Izumi; A Wada
Effects of protonophores on the synthesis of catecholamines and the intracellular pH in cultured bovine adrenal medullary cells.
Journal of neurochemistry 1988;51(1):246-51.
1988: A Wada; M Arita; Nobuyuki Yanagihara; Futoshi Izumi
Binding of [3H]phencyclidine to adrenal medullary cells: inhibition of 22Na influx, 45Ca influx, 86Rb efflux and catecholamine secretion caused by carbachol and veratridine.
Neuroscience 1988;25(2):687-96.
1987: Nobuyuki Yanagihara; K Yokota; A Wada; Futoshi Izumi
Intracellular pH and catecholamine synthesis in cultured bovine adrenal medullary cells: effect of extracellular Na+ removal.
Journal of neurochemistry 1987;49(6):1740-6.
1987: Nobuyuki Yanagihara; A Wada; Futoshi Izumi
Effects of alpha 2-adrenergic agonists on carbachol-stimulated catecholamine synthesis in cultured bovine adrenal medullary cells.
Biochemical pharmacology 1987;36(22):3823-8.
1987: A Wada; H Kobayashi; M Arita; Nobuyuki Yanagihara; Futoshi Izumi
Potassium channels in cultured bovine adrenal medullary cells: effects of high K, veratridine and carbachol on 86rubidium efflux.
Neuroscience 1987;22(3):1085-92.
1981: Futoshi Izumi; A Wada; Nobuyuki Yanagihara; Yumiko Toyohira; K Okuda; Takeshi Kashimoto
[Intracellular mechanism for the release of adrenal catecholamine (author's transl)].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1981;26(11):1651-6.