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Chinglai Yang

Research Profile

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Immunization

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Membrane Fusion

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Publications

TOP 3
Dongni Kong; Hua Su; Xijun Wang; Zhiyuan Wen; Chao Wu; Chinglai Yang; Hualan Chen; Weiye Chen; Jinying Ge; Zhigao Bu
Newcastle disease virus-vectored Nipah encephalitis vaccines induce B and T cell responses in mice and long-lasting neutralizing antibodies in pigs.
Gopi S Mohan; Richard W Compans; Wenfang Li; Ling Ye; Chinglai Yang
Antigenic subversion: a novel mechanism of host immune evasion by Ebola virus.
Yulong Gao; Xiaomei Wang; Zhiyuan Wen; Zhigao Bu; Hualan Chen; Ke Dong; Ling Ye; Gongxun Zhong; Chinglai Yang
Characterization of immune responses induced by immunization with the HA DNA vaccines of two antigenically distinctive H5N1 HPAIV isolates.

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All Publications

2012: Dongni Kong; Hua Su; Xijun Wang; Zhiyuan Wen; Chao Wu; Chinglai Yang; Hualan Chen; Weiye Chen; Jinying Ge; Zhigao Bu
Newcastle disease virus-vectored Nipah encephalitis vaccines induce B and T cell responses in mice and long-lasting neutralizing antibodies in pigs.
Virology 2012;432(2):327-35.
2012: Gopi S Mohan; Richard W Compans; Wenfang Li; Ling Ye; Chinglai Yang
Antigenic subversion: a novel mechanism of host immune evasion by Ebola virus.
PLoS pathogens 2012;8(12):e1003065.
2012: Yulong Gao; Xiaomei Wang; Zhiyuan Wen; Zhigao Bu; Hualan Chen; Ke Dong; Ling Ye; Gongxun Zhong; Chinglai Yang
Characterization of immune responses induced by immunization with the HA DNA vaccines of two antigenically distinctive H5N1 HPAIV isolates.
PloS one 2012;7(7):e41332.
2012: Chuan-Liang Kao; Ta-Chien Chan; Luan-Yin Chang; Kuan-Ying Chu; Shu-Fang Chuang; Richard W Compans; Li-Min Huang; Chang-Chun Lee; Ping-Ing Lee; Zheng-Rong Tiger Li; Barry T Rouse; Yea-Huei Shen; Chu-Han Tsai; Ko-Wen Wu; Chinglai Yang; Chwan-Chuen King
Emerged HA and NA mutants of the pandemic influenza H1N1 viruses with increasing epidemiological significance in Taipei and Kaohsiung, Taiwan, 2009-10.
PloS one 2012;7(2):e31162.
2011: Jinying Ge; Lihong Tao; Xijun Wang; Zhiyuan Wen; Xianzhu Xia; Chinglai Yang; Songtao Yang; Hualan Chen; Na Feng; Zhigao Bu
Newcastle disease virus-vectored rabies vaccine is safe, highly immunogenic, and provides long-lasting protection in dogs and cats.
Journal of virology 2011;85(16):8241-52.
2011: Lihong Tao; Xijun Wang; Zhiyuan Wen; Chinglai Yang; Hongyue Zhai; Bolin Zhao; Jinying Ge; Tao Hua; Dongni Kong; Zhigao Bu
Generation of a recombinant rabies Flury LEP virus carrying an additional G gene creates an improved seed virus for inactivated vaccine production.
Virology journal 2011;8():454.
2011: Ling Ye; Zhiyuan Wen; Ke Dong; Xi Wang; Zhigao Bu; Huizhong Zhang; Richard W Compans; Chinglai Yang
Induction of HIV neutralizing antibodies against the MPER of the HIV envelope protein by HA/gp41 chimeric protein-based DNA and VLP vaccines.
PloS one 2011;6(5):e14813.
2010: Lihong Tao; Jinying Ge; Xijun Wang; Hongyue Zhai; Tao Hua; Bolin Zhao; Dongni Kong; Chinglai Yang; Hualan Chen; Zhigao Bu
Molecular basis of neurovirulence of flury rabies virus vaccine strains: importance of the polymerase and the glycoprotein R333Q mutation.
Journal of virology 2010;84(17):8926-36.
2010: Ling Ye; Zhiyuan Wen; Ke Dong; Lei Pan; Zhigao Bu; Richard W Compans; Huizhong Zhang; Chinglai Yang
Immunization with a Mixture of HIV Env DNA and VLP Vaccines Augments Induction of CD8 T Cell Responses.
Journal of biomedicine & biotechnology 2010;2010():497219.
2009: Zhiyuan Wen; Ling Ye; Yulong Gao; Lei Pan; Ke Dong; Zhigao Bu; Richard W Compans; Chinglai Yang
Immunization by influenza virus-like particles protects aged mice against lethal influenza virus challenge.
Antiviral research 2009;84(3):215-24.
2009: Qiyun Zhu; Vladimir G Zarnitsyn; Ling Ye; Zhiyuan Wen; Yulong Gao; Lei Pan; Ioanna Skountzou; Harvinder S Gill; Mark R Prausnitz; Chinglai Yang; Richard W Compans
Immunization by vaccine-coated microneedle arrays protects against lethal influenza virus challenge.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(19):7968-73.
2009: Yuliang Sun; Ricardo Carrion; Ling Ye; Zhiyuan Wen; Young-Tae Ro; Kathleen Brasky; Anysha E Ticer; E Ellen Schwegler; Jean L Patterson; Richard W Compans; Chinglai Yang
Protection against lethal challenge by Ebola virus-like particles produced in insect cells.
Virology 2009;383(1):12-21.
2008: Chinglai Yang; Ling Ye; Richard W Compans
Protection against filovirus infection: virus-like particle vaccines.
Expert review of vaccines 2008;7(3):333-44.
2008: Milan Raska; Zina Moldoveanu; Jan Novak; Zdenek Hel; Lea Novak; Jadranka Bozja; Richard W Compans; Chinglai Yang; Jiri Mestecky
Delivery of DNA HIV-1 vaccine to the liver induces high and long-lasting humoral immune responses.
Vaccine 2008;26(12):1541-51.
2008: Qiyun Zhu; Huanliang Yang; Weiye Chen; Wenyan Cao; Gongxun Zhong; peirong jiao; Guohua Deng; Kangzhen Yu; Chinglai Yang; Zhigao Bu; Yoshihiro Kawaoka; Hualan Chen
A naturally occurring deletion in its NS gene contributes to the attenuation of an H5N1 swine influenza virus in chickens.
Journal of virology 2008;82(1):220-8.
2007: Jinying Ge; Guohua Deng; Zhiyuan Wen; Guobing Tian; Yong Wang; Jianzhong Shi; Xijun Wang; Yanbing Li; Sen Hu; Yongping Jiang; Chinglai Yang; Kangzhen Yu; Zhigao Bu; Hualan Chen
Newcastle disease virus-based live attenuated vaccine completely protects chickens and mice from lethal challenge of homologous and heterologous H5N1 avian influenza viruses.
Journal of virology 2007;81(1):150-8.
2006: Ling Ye; Yuliang Sun; Jianguo Lin; Zhigao Bu; Qingyang Wu; Shibo Jiang; David A Steinhauer; Richard W Compans; Chinglai Yang
Antigenic properties of a transport-competent influenza HA/HIV Env chimeric protein.
Virology 2006;352(1):74-85.
2006: Ling Ye; Jianguo Lin; Yuliang Sun; Soumaya Bennouna; Michael Lo; Qingyang Wu; Zhigao Bu; Bali Pulendran; Richard W Compans; Chinglai Yang
Ebola virus-like particles produced in insect cells exhibit dendritic cell stimulating activity and induce neutralizing antibodies.
Virology 2006;351(2):260-70.
2006: Min Li; Zhu-Nan Li; Qizhi Yao; Chinglai Yang; David A Steinhauer; Richard W Compans
Murine leukemia virus R Peptide inhibits influenza virus hemagglutinin-induced membrane fusion.
Journal of virology 2006;80(12):6106-14.
2005: Zhu-Nan Li; Scott N Mueller; Ling Ye; Zhigao Bu; Chinglai Yang; Rafi Ahmed; David A Steinhauer
Chimeric influenza virus hemagglutinin proteins containing large domains of the Bacillus anthracis protective antigen: protein characterization, incorporation into infectious influenza viruses, and antigenicity.
Journal of virology 2005;79(15):10003-12.
2005: Sang-Moo Kang; Fu-Shi Quan; Chunzi Huang; Lizheng Guo; Ling Ye; Chinglai Yang; Richard W Compans
Modified HIV envelope proteins with enhanced binding to neutralizing monoclonal antibodies.
Virology 2005;331(1):20-32.
2004: Ling Ye; Zhigao Bu; Andrei N Vzorov; Dahnide Taylor; Richard W Compans; Chinglai Yang
Surface stability and immunogenicity of the human immunodeficiency virus envelope glycoprotein: role of the cytoplasmic domain.
Journal of virology 2004;78(24):13409-19.
2004: Zhigao Bu; Ling Ye; Andrei N Vzorov; Dahnide Taylor; Richard W Compans; Chinglai Yang
Enhancement of immunogenicity of an HIV Env DNA vaccine by mutation of the Tyr-based endocytosis motif in the cytoplasmic domain.
Virology 2004;328(1):62-73.
2003: Ling Ye; Zhigao Bu; Marianne J Skeen; H Kirk Ziegler; Richard W Compans; Chinglai Yang
Enhanced immunogenicity of SIV Gag DNA vaccines encoding chimeric proteins containing a C-terminal segment of Listeriolysin O.
Virus research 2003;97(1):7-16.
2003: Zhigao Bu; Ling Ye; Richard W Compans; Chinglai Yang
Enhanced cellular immune response against SIV Gag induced by immunization with DNA vaccines expressing assembly and release-defective SIV Gag proteins.
Virology 2003;309(2):272-81.
2003: Zhigao Bu; Ling Ye; Marianne J Skeen; H Kirk Ziegler; Richard W Compans; Chinglai Yang
Enhancement of immune responses to an HIV env DNA vaccine by a C-terminal segment of listeriolysin O.
AIDS research and human retroviruses 2003;19(5):409-20.
2003: Qizhi Yao; Zhigao Bu; Andrei N Vzorov; Chinglai Yang; Richard W Compans
Virus-like particle and DNA-based candidate AIDS vaccines.
Vaccine 2003;21(7-8):638-43.
2002: Min Li; Chinglai Yang; Suxiang Tong; Armin Weidmann; Richard W Compans
Palmitoylation of the murine leukemia virus envelope protein is critical for lipid raft association and surface expression.
Journal of virology 2002;76(23):11845-52.
2001: M Li; Chinglai Yang; Richard W Compans
Mutations in the cytoplasmic tail of murine leukemia virus envelope protein suppress fusion inhibition by R peptide.
Journal of virology 2001;75(5):2337-44.
2000: Chinglai Yang; Q Yang; Richard W Compans
Coreceptor-dependent inhibition of the cell fusion activity of simian immunodeficiency virus Env proteins.
Journal of virology 2000;74(13):6217-22.
1997: Chinglai Yang; Richard W Compans
Analysis of the murine leukemia virus R peptide: delineation of the molecular determinants which are important for its fusion inhibition activity.
Journal of virology 1997;71(11):8490-6.
1997: Joanna L Shisler; Chinglai Yang; B Walter; Carl Ware; Linda R Gooding
The adenovirus E3-10.4K/14.5K complex mediates loss of cell surface Fas (CD95) and resistance to Fas-induced apoptosis.
Journal of virology 1997;71(11):8299-306.
1996: Chinglai Yang; Richard W Compans
Palmitoylation of the murine leukemia virus envelope glycoprotein transmembrane subunits.
Virology 1996;221(1):87-97.
1996: Chinglai Yang; Richard W Compans
Analysis of the cell fusion activities of chimeric simian immunodeficiency virus-murine leukemia virus envelope proteins: inhibitory effects of the R peptide.
Journal of virology 1996;70(1):248-54.
1995: Chinglai Yang; C P Spies; Richard W Compans
The human and simian immunodeficiency virus envelope glycoprotein transmembrane subunits are palmitoylated.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9871-5.