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Chung Yang

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Zheng-Yuan Su; Nanjoo Suh; Qing Wu; Tien-Yuan Wu; Chung S Yang; Allan H Conney; Ying Huang; Tin Oo Khor; Jong Hun Lee; Constance Lay-Lay Saw; Limin Shu; Ah-Ng Tony Kong
Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 cells by natural phytochemicals Z-ligustilide and Radix angelica sinensis via promoter CpG demethylation.
Tait D Shanafelt; Chung S Yang; Clive S Zent; Deborah A Bowen; Timothy G Call; Charles Erlichman; Asish K Ghosh; Diane F Jelinek; Betsy LaPlant; Kristina Laumann; Mao-Jung Lee; Jose F Leis; Connie Lesnick; Michelle Roos; Neil E Kay
Phase 2 trial of daily, oral Polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia.
Chung S Yang; Nanjoo Suh
Cancer prevention by different forms of tocopherols.

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All Publications

2013: Zheng-Yuan Su; Nanjoo Suh; Qing Wu; Tien-Yuan Wu; Chung S Yang; Allan H Conney; Ying Huang; Tin Oo Khor; Jong Hun Lee; Constance Lay-Lay Saw; Limin Shu; Ah-Ng Tony Kong
Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 cells by natural phytochemicals Z-ligustilide and Radix angelica sinensis via promoter CpG demethylation.
Chemical research in toxicology 2013;26(3):477-85.
2013: Tait D Shanafelt; Chung S Yang; Clive S Zent; Deborah A Bowen; Timothy G Call; Charles Erlichman; Asish K Ghosh; Diane F Jelinek; Betsy LaPlant; Kristina Laumann; Mao-Jung Lee; Jose F Leis; Connie Lesnick; Michelle Roos; Neil E Kay
Phase 2 trial of daily, oral Polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia.
Cancer 2013;119(2):363-70.
2013: Chung S Yang; Nanjoo Suh
Cancer prevention by different forms of tocopherols.
Topics in current chemistry 2013;329():21-33.
2012: Amanda K Smolarek; Jae Young So; Chung S Yang; Brenda Burgess; Yu-Kuo Chen; Ah-Ng Tony Kong; Mao-Jung Lee; Guangxun Li; Yong Lin; Kenneth R Reuhl; Weichung Joe Shih; Nanjoo Suh
Dietary administration of δ- and γ-tocopherol inhibits tumorigenesis in the animal model of estrogen receptor-positive, but not HER-2 breast cancer.
Cancer prevention research (Philadelphia, Pa.) 2012;5(11):1310-20.
2012: Fei Guan; Guangxun Li; Anna B Liu; Yuhai Sun; Chung S Yang; Zhihong Yang; Jihyeung Ju
Deleterious effects of high concentrations of (-)-epigallocatechin-3-gallate and atorvastatin in mice with colon inflammation.
Nutrition and cancer 2012;64(6):847-55.
2012: Guangxun Li; Anna B Liu; Kenneth R Reuhl; Hong Wang; Maarten C Bosland; Connie Cheung; Chung S Yang
Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice.
Cancer prevention research (Philadelphia, Pa.) 2012;5(7):963-72.
2012: Chung S Yang; Eva Pan
The effects of green tea polyphenols on drug metabolism.
Expert opinion on drug metabolism & toxicology 2012;8(6):677-89.
2012: Chung S Yang; Nanjoo Suh; Ah-Ng Tony Kong
Does vitamin E prevent or promote cancer?
Cancer prevention research (Philadelphia, Pa.) 2012;5(5):701-5.
2012: Fei Guan; Mao-Jung Lee; Guangxun Li; Yong Lin; Anna B Liu; Weichung Shih; Yu-Kuo Chen; Zhihong Yang; Chung S Yang
δ- and γ-tocopherols, but not α-tocopherol, inhibit colon carcinogenesis in azoxymethane-treated F344 rats.
Cancer prevention research (Philadelphia, Pa.) 2012;5(4):644-54.
2012: Guangxun Li; Yong Lin; Anna Ba Liu; Weichung Joe Shih; Mao-Jung Lee; Zhihong Yang; Chung S Yang
The antioxidant and anti-inflammatory activities of tocopherols are independent of Nrf2 in mice.
Free radical biology & medicine 2012;52(7):1151-8.
2012: Xi Zheng; Xiao-Xing Cui; Mou-Tuan Huang; Mao-Jung Lee; Yong Lin; Yue Liu; Weichung Joe Shih; George C Wagner; Chung S Yang; Allan H Conney
Inhibition of progression of androgen-dependent prostate LNCaP tumors to androgen independence in SCID mice by oral caffeine and voluntary exercise.
Nutrition and cancer 2012;64(7):1029-37.
2011: Hong Wang; Shengjie Bian; Chung S Yang
Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1α.
Carcinogenesis 2011;32(12):1881-9.
2011: Yu-Kuo Chen; Connie Cheung; Mao-Jung Lee; Anna Ba Liu; Yao-Ping Lu; Kenneth R Reuhl; Chung S Yang
Effects of green tea polyphenol (-)-epigallocatechin-3-gallate on newly developed high-fat/Western-style diet-induced obesity and metabolic syndrome in mice.
Journal of agricultural and food chemistry 2011;59(21):11862-71.
2011: Chung S Yang; Joshua D Lambert
Research on tea and health.
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;64(2):85-6.
2011: Chung S Yang; Zhihong Yang; Fei Guan; Guang Xun Li; Hong Wang; Huanyu Jin
Cancer prevention by tea: Evidence from laboratory studies.
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;64(2):113-22.
2011: Chung S Yang; Hong Wang
Mechanistic issues concerning cancer prevention by tea catechins.
Molecular nutrition & food research 2011;55(6):819-31.
2011: Connie Cheung; Shea Loy; Guang Xun Li; Anna B Liu; Chung S Yang
Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate.
Carcinogenesis 2011;32(2):233-9.
2010: Joshua D Lambert; Shengmin Sang; Jungil Hong; Chung S Yang
Anticancer and anti-inflammatory effects of cysteine metabolites of the green tea polyphenol, (-)-epigallocatechin-3-gallate.
Journal of agricultural and food chemistry 2010;58(18):10016-9.
2010: Chung S Yang; Gang Lu; Jihyeung Ju; Guang Xun Li
Inhibition of inflammation and carcinogenesis in the lung and colon by tocopherols.
Annals of the New York Academy of Sciences 2010;1203():29-34.
2010: Jung-Hyun Shim; Zheng-Yuan Su; Jung-Il Chae; Dong Joon Kim; Feng Zhu; Wei-Ya Ma; Ann M Bode; Chung S Yang; Zigang Dong
Epigallocatechin gallate suppresses lung cancer cell growth through Ras-GTPase-activating protein SH3 domain-binding protein 1.
Cancer prevention research (Philadelphia, Pa.) 2010;3(5):670-9.
2010: Guang-Xun Li; Yu-Kuo Chen; Zhe Hou; Hang Xiao; Huanyu Jin; Gary Lu; Mao-Jung Lee; Ba Liu; Fei Guan; Zhihong Yang; Albert Yu; Chung S Yang
Pro-oxidative activities and dose-response relationship of (-)-epigallocatechin-3-gallate in the inhibition of lung cancer cell growth: a comparative study in vivo and in vitro.
Carcinogenesis 2010;31(5):902-10.
2010: Gang Lu; Hang Xiao; Guang-Xun Li; Sonia C Picinich; Yu-Kuo Chen; Anna Liu; Mao-Jung Lee; Shea Loy; Chung S Yang
A gamma-tocopherol-rich mixture of tocopherols inhibits chemically induced lung tumorigenesis in A/J mice and xenograft tumor growth.
Carcinogenesis 2010;31(4):687-94.
2010: Jihyeung Ju; Sonia C Picinich; Zhihong Yang; Yang Zhao; Nanjoo Suh; Ah-Ng Kong; Chung S Yang
Cancer-preventive activities of tocopherols and tocotrienols.
Carcinogenesis 2010;31(4):533-42.
2010: Zhihong Yang; Hang Xiao; Huanyu Jin; Phillip T Koo; Dorothea J Tsang; Chung S Yang
Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells.
International journal of cancer. Journal international du cancer 2010;126(4):852-63.
2010: Chung S Yang; Xin Wang
Green tea and cancer prevention.
Nutrition and cancer 2010;62(7):931-7.
2010: Xi Zheng; Xiao-Xing Cui; Zhi Gao; Yang Zhao; Yong Lin; Weichung Joe Shih; Mou-Tuan Huang; Yue Liu; Arnold Rabson; Bandaru Reddy; Chung S Yang; Allan H Conney
Atorvastatin and celecoxib in combination inhibits the progression of androgen-dependent LNCaP xenograft prostate tumors to androgen independence.
Cancer prevention research (Philadelphia, Pa.) 2010;3(1):114-24.
2010: Joshua D Lambert; Mary J. Kennett; Shengmin Sang; Kenneth R Reuhl; Jihyeung Ju; Chung S Yang
Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2010;48(1):409-16.
2009: Shengmin Sang; Jungil Hong; Hou Wu; Jing Liu; Chung S Yang; Min-Hsiung Pan; Vladimir Badmaev; Chi-Tang Ho
Increased growth inhibitory effects on human cancer cells and anti-inflammatory potency of shogaols from Zingiber officinale relative to gingerols.
Journal of agricultural and food chemistry 2009;57(22):10645-50.
2009: Tait D Shanafelt; Timothy G Call; Clive S Zent; Betsy LaPlant; Deborah A Bowen; Michelle Roos; Charla R Secreto; Asish K Ghosh; Brian Kabat; Mao-Jung Lee; Chung S Yang; Diane F Jelinek; Charles Erlichman; Neil E Kay
Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(23):3808-14.
2009: Joshua D Lambert; Gang Lu; Mao-Jung Lee; Jennifer Hu; Jihyeung Ju; Chung S Yang
Inhibition of lung cancer growth in mice by dietary mixed tocopherols.
Molecular nutrition & food research 2009;53(8):1030-5.
2009: Hong Jin Lee; Jihyeung Ju; Shiby Paul; Jae-Young So; Andrew DeCastro; Amanda Smolarek; Mao-Jung Lee; Chung S Yang; Harold L Newmark; Nanjoo Suh
Mixed tocopherols prevent mammary tumorigenesis by inhibiting estrogen action and activating PPAR-gamma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(12):4242-9.
2009: Chung S Yang; Xin Wang; Gang Lu; Sonia C Picinich
Cancer prevention by tea: animal studies, molecular mechanisms and human relevance.
Nature reviews. Cancer 2009;9(6):429-39.
2009: Jing Hao; Bin Zhang; Ba Liu; Maojung Lee; Xingpei Hao; Kenneth R Reuhl; Xiaoxin Chen; Chung S Yang
Effect of alpha-tocopherol, N-acetylcysteine and omeprazole on esophageal adenocarcinoma formation in a rat surgical model.
International journal of cancer. Journal international du cancer 2009;124(6):1270-5.
2009: Hang Xiao; Chung S Yang; Shiming Li; Huanyu Jin; Chi-Tang Ho; Trusha Patel
Monodemethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel inhibit growth of human lung cancer cells by apoptosis.
Molecular nutrition & food research 2009;53(3):398-406.
2009: Jihyeung Ju; Xingpei Hao; Mao-Jung Lee; Joshua D Lambert; Gang Lu; Hang Xiao; Harold L Newmark; Chung S Yang
A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice.
Cancer prevention research (Philadelphia, Pa.) 2009;2(2):143-52.
2009: Jing Hao; Ba Liu; Chung S Yang; Xiaoxin Chen
Gastroesophageal reflux leads to esophageal cancer in a surgical model with mice.
BMC gastroenterology 2009;9():59.
2009: Chung S Yang; Joshua D Lambert; Shengmin Sang
Antioxidative and anti-carcinogenic activities of tea polyphenols.
Archives of toxicology 2009;83(1):11-21.
2008: Shengmin Sang; Chung S Yang
Structural identification of novel glucoside and glucuronide metabolites of (-)-epigallocatechin-3-gallate in mouse urine using liquid chromatography/electrospray ionization tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM 2008;22(22):3693-9.
2008: xi shao; Naisheng Bai; Kan He; Chi-Tang Ho; Chung S Yang; Shengmin Sang
Apple polyphenols, phloretin and phloridzin: new trapping agents of reactive dicarbonyl species.
Chemical research in toxicology 2008;21(10):2042-50.
2008: Joshua D Lambert; Seok Joo Kwon; Jihyeung Ju; Mousumi Bose; Mao-Jung Lee; Jungil Hong; Xingpei Hao; Chung S Yang
Effect of genistein on the bioavailability and intestinal cancer chemopreventive activity of (-)-epigallocatechin-3-gallate.
Carcinogenesis 2008;29(10):2019-24.
2008: Mousumi Bose; Joshua D Lambert; Jihyeung Ju; Kenneth R Reuhl; Sue A Shapses; Chung S Yang
The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice.
The Journal of nutrition 2008;138(9):1677-83.
2008: Hang Xiao; Chung S Yang
Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention.
International journal of cancer. Journal international du cancer 2008;123(5):983-90.
2008: Xin Zhang; Hongzheng Zhang; Mourad Tighiouart; John E Lee; Hyung J Shin; Fadlo R Khuri; Chung S Yang; Zhuo Georgia Chen; Dong M Shin
Synergistic inhibition of head and neck tumor growth by green tea (-)-epigallocatechin-3-gallate and EGFR tyrosine kinase inhibitor.
International journal of cancer. Journal international du cancer 2008;123(5):1005-14.
2008: Avantika Barve; Tin Oo Khor; Xingpei Hao; Young-Sam Keum; Chung S Yang; Bandaru Reddy; Ah-Ng Tony Kong
Murine prostate cancer inhibition by dietary phytochemicals--curcumin and phenyethylisothiocyanate.
Pharmaceutical research 2008;25(9):2181-9.
2008: Tin Oo Khor; Mou-Tuan Huang; Auemduan Prawan; Yue Liu; Xingpei Hao; Siwang Yu; William Ka Lung Cheung; Jefferson Y Chan; Bandaru S Reddy; Chung S Yang; Ah-Ng Tony Kong
Increased susceptibility of Nrf2 knockout mice to colitis-associated colorectal cancer.
Cancer prevention research (Philadelphia, Pa.) 2008;1(3):187-91.
2008: Gang Lu; Hang Xiao; Hui You; Yong Lin; Huanyu Jin; Blake Snagaski; Chung S Yang
Synergistic inhibition of lung tumorigenesis by a combination of green tea polyphenols and atorvastatin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(15):4981-8.
2008: Chung S Yang; Mingzhu Fang; Joshua D Lambert; Pearly Yan; Hui-Ming (Tim) Huang
Reversal of hypermethylation and reactivation of genes by dietary polyphenolic compounds.
Nutrition reviews 2008;66 Suppl 1():S18-20.
2008: Yingying Liu; Hang Xiao; Yanmei Tian; Tanya Nekrasova; Xingpei Hao; Hong Jin Lee; Nanjoo Suh; Chung S Yang; Audrey Minden
The pak4 protein kinase plays a key role in cell survival and tumorigenesis in athymic mice.
Molecular cancer research : MCR 2008;6(7):1215-24.
2008: Zheng Sun; Sandeep Sood; Ning Li; Peiying Yang; Robert A Newman; Chung S Yang; Xiaoxin Chen
Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch by topical application of a dual inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 tyrosine kinases.
Oral oncology 2008;44(7):652-7.
2008: Chung S Yang; Shengmin Sang; Joshua D Lambert; Mao-Jung Lee
Bioavailability issues in studying the health effects of plant polyphenolic compounds.
Molecular nutrition & food research 2008;52 Suppl 1():S139-51.
2008: Shengmin Sang; Mao-Jung Lee; Ill Yang; Brian Buckley; Chung S Yang
Human urinary metabolite profile of tea polyphenols analyzed by liquid chromatography/electrospray ionization tandem mass spectrometry with data-dependent acquisition.
Rapid communications in mass spectrometry : RCM 2008;22(10):1567-78.
2008: Hang Xiao; Qiang Zhang; Yong Lin; Bandaru S Reddy; Chung S Yang
Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells.
International journal of cancer. Journal international du cancer 2008;122(9):2115-24.
2008: Joshua D Lambert; Shengmin Sang; Chung S Yang
N-Acetylcysteine enhances the lung cancer inhibitory effect of epigallocatechin-3-gallate and forms a new adduct.
Free radical biology & medicine 2008;44(6):1069-74.
2008: Zhiwei He; Faqing Tang; Svetlana Ermakova; Ming Li; Qing Zhao; Yong-Yeon Cho; Wei-Ya Ma; Hong-Seok Choi; Ann M Bode; Chung S Yang; Zigang Dong
Fyn is a novel target of (-)-epigallocatechin gallate in the inhibition of JB6 Cl41 cell transformation.
Molecular carcinogenesis 2008;47(3):172-83.
2008: Jihyeung Ju; Bonnie Nolan; Michelle Cheh; Mousumi Bose; Yong Lin; George C Wagner; Chung S Yang
Voluntary exercise inhibits intestinal tumorigenesis in Apc(Min/+) mice and azoxymethane/dextran sulfate sodium-treated mice.
BMC cancer 2008;8():316.
2008: Yingying Liu; Jihyeung Ju; Hang Xiao; Barbara Simi; Xingpei Hao; Bandaru S Reddy; Mou-Tuan Huang; Harold L Newmark; Chung S Yang
Effects of combination of calcium and aspirin on azoxymethane-induced aberrant crypt foci formation in the colons of mice and rats.
Nutrition and cancer 2008;60(5):660-5.
2008: Chung S Yang; Jihyeung Ju; Gary Lu; Hang Xiao; Xingpei Hao; Shengmin Sang; Joshua D Lambert
Cancer prevention by tea and tea polyphenols.
Asia Pacific journal of clinical nutrition 2008;17 Suppl 1():245-8.
2008: Xiaoxin Chen; Rong Qin; Ba Liu; Yan Ma; Yinghao Su; Chung S Yang; Jonathan N Glickman; Robert D Odze; Nicholas J Shaheen
Multilayered epithelium in a rat model and human Barrett's esophagus: similar expression patterns of transcription factors and differentiation markers.
BMC gastroenterology 2008;8():1.
2008: Hang Xiao; Xingpei Hao; Barbara Simi; Jihyeung Ju; Heyuan Jiang; Bandaru S Reddy; Chung S Yang
Green tea polyphenols inhibit colorectal aberrant crypt foci (ACF) formation and prevent oncogenic changes in dysplastic ACF in azoxymethane-treated F344 rats.
Carcinogenesis 2008;29(1):113-9.
2007: Shengmin Sang; xi shao; Naisheng Bai; Chih-Yu Lo; Chung S Yang; Chi-Tang Ho
Tea polyphenol (-)-epigallocatechin-3-gallate: a new trapping agent of reactive dicarbonyl species.
Chemical research in toxicology 2007;20(12):1862-70.
2007: Joshua D Lambert; Shengmin Sang; Chung S Yang
Biotransformation of green tea polyphenols and the biological activities of those metabolites.
Molecular pharmaceutics 2007;4(6):819-25.
2007: Chung S Yang; Joshua D Lambert; Jihyeung Ju; Gang Lu; Shengmin Sang
Tea and cancer prevention: molecular mechanisms and human relevance.
Toxicology and applied pharmacology 2007;224(3):265-73.
2007: Allan H Conney; Sherry Zhou; Mao-Jung Lee; Jian-Guo Xie; Chung S Yang; You-Rong Lou; YaoPing Lu
Stimulatory effect of oral administration of tea, coffee or caffeine on UVB-induced apoptosis in the epidermis of SKH-1 mice.
Toxicology and applied pharmacology 2007;224(3):209-13.
2007: Yarí E Marín; Brian A Wall; Su Wang; Jin Namkoong; Jeffrey J Martino; Junghan Suh; Hwa Jin Lee; Arnold B Rabson; Chung S Yang; Suzie Chen; Jae-Ha Ryu
Curcumin downregulates the constitutive activity of NF-kappaB and induces apoptosis in novel mouse melanoma cells.
Melanoma research 2007;17(5):274-83.
2007: Jihyeung Ju; Gang Lu; Joshua D Lambert; Chung S Yang
Inhibition of carcinogenesis by tea constituents.
Seminars in cancer biology 2007;17(5):395-402.
2007: Mousumi Bose; Xingpei Hao; Jihyeung Ju; Ali Husain; Sunny Park; Joshua D Lambert; Chung S Yang
Inhibition of tumorigenesis in ApcMin/+ mice by a combination of (-)-epigallocatechin-3-gallate and fish oil.
Journal of agricultural and food chemistry 2007;55(19):7695-700.
2007: Shiming Li; Shengmin Sang; Min-Hsiung Pan; Ching-Shu Lai; Chih-Yu Lo; Chung S Yang; Chi-Tang Ho
Anti-inflammatory property of the urinary metabolites of nobiletin in mouse.
Bioorganic & medicinal chemistry letters 2007;17(18):5177-81.
2007: Shengmin Sang; Ill Yang; Brian Buckley; Chi-Tang Ho; Chung S Yang
Autoxidative quinone formation in vitro and metabolite formation in vivo from tea polyphenol (-)-epigallocatechin-3-gallate: studied by real-time mass spectrometry combined with tandem mass ion mapping.
Free radical biology & medicine 2007;43(3):362-71.
2007: Ronald A Lubet; Chung S Yang; Mao-Jung Lee; Yukihiko Hara; Izet M Kapetanovic; James A Crowell; Vernon E Steele; M Margaret Juliana; Clinton J Grubbs
Preventive effects of polyphenon E on urinary bladder and mammary cancers in rats and correlations with serum and urine levels of tea polyphenols.
Molecular cancer therapeutics 2007;6(7):2022-8.
2007: Joshua D Lambert; Seok Joo Kwon; Jungil Hong; Chung S Yang
Salivary hydrogen peroxide produced by holding or chewing green tea in the oral cavity.
Free radical research 2007;41(7):850-3.
2007: Joshua D Lambert; Shengmin Sang; Anthony Y H Lu; Chung S Yang
Metabolism of dietary polyphenols and possible interactions with drugs.
Current drug metabolism 2007;8(5):499-507.
2007: Yuyang Christine Cai; Chi-Kwong So; Alex Yan Nie; Yunlong Song; Guang-Yu Yang; Li-Dong Wang; Xin Zhao; Terri Goss Kinzy; Chung S Yang
Characterization of genetic alteration patterns in human esophageal squamous cell carcinoma using selected microsatellite markers spanning multiple loci.
International journal of oncology 2007;30(5):1059-67.
2007: Jungil Hong; Seok Joo Kwon; Shengmin Sang; Jihyeung Ju; Jian-nian Zhou; Chi-Tang Ho; Mou-Tuan Huang; Chung S Yang
Effects of garcinol and its derivatives on intestinal cell growth: Inhibitory effects and autoxidation-dependent growth-stimulatory effects.
Free radical biology & medicine 2007;42(8):1211-21.
2007: Joshua D Lambert; Shengmin Sang; Chung S Yang
Possible controversy over dietary polyphenols: benefits vs risks.
Chemical research in toxicology 2007;20(4):583-5.
2007: Jian-Min Yuan; Yu-Tang Gao; Chung S Yang; Mimi C Yu
Urinary biomarkers of tea polyphenols and risk of colorectal cancer in the Shanghai Cohort Study.
International journal of cancer. Journal international du cancer 2007;120(6):1344-50.
2007: Tong Liu; Xinyan Zhang; Chi-Kwong So; Su Wang; Peng Wang; Liying Yan; Rene Myers; Zhigang Chen; Amy P Patterson; Chung S Yang; Xiaoxin Chen
Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells.
Carcinogenesis 2007;28(2):488-96.
2007: Nanjoo Suh; Shiby Paul; Hong Jin Lee; Yan Ji; Mao-Jung Lee; Chung S Yang; Bandaru S Reddy; Harold L Newmark
Mixed tocopherols inhibit N-methyl-N-nitrosourea-induced mammary tumor growth in rats.
Nutrition and cancer 2007;59(1):76-81.
2007: Xingpei Hao; Yuhai Sun; Chung S Yang; Mousumi Bose; Joshua D Lambert; Jihyeung Ju; Gang Lu; Mao-Jung Lee; Sunny Park; Ali Husain; Steven Wang
Inhibition of intestinal tumorigenesis in Apc(min/+) mice by green tea polyphenols (polyphenon E) and individual catechins.
Nutrition and cancer 2007;59(1):62-9.
2007: Mingzhu Fang; Dapeng Chen; Chung S Yang
Dietary polyphenols may affect DNA methylation.
The Journal of nutrition 2007;137(1 Suppl):223S-228S.
2006: Shengmin Sang; Jihyeung Ju; Joshua D Lambert; Yong Lin; Jungil Hong; Mousumi Bose; Steven Wang; Naisheng Bai; Kan He; Bandaru S Reddy; Chi-Tang Ho; Frederick P Li; Chung S Yang
Wheat bran oil and its fractions inhibit human colon cancer cell growth and intestinal tumorigenesis in Apc(min/+) mice.
Journal of agricultural and food chemistry 2006;54(26):9792-7.
2006: Gang Lu; Jie Liao; Guang-Yu Yang; Kenneth R Reuhl; Xingpei Hao; Chung S Yang
Inhibition of adenoma progression to adenocarcinoma in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model in A/J mice by tea polyphenols and caffeine.
Cancer research 2006;66(23):11494-501.
2006: Joshua D Lambert; Shengmin Sang; Jungil Hong; Seok Joo Kwon; Mao-Jung Lee; Chi-Tang Ho; Chung S Yang
Peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(12):2111-6.
2006: Xiaoxin Chen; Sandeep Sood; Chung S Yang; Ning Li; Zheng Sun
Five-lipoxygenase pathway of arachidonic acid metabolism in carcino-genesis and cancer chemoprevention.
Current cancer drug targets 2006;6(7):613-22.
2006: Chung S Yang
Dietary factors may modify cancer risk by altering xenobiotic metabolism and many other mechanisms.
The Journal of nutrition 2006;136(10):2685S-6S.
2006: Liang-Ru Zhu; Paul E Thomas; Gang Lu; Kenneth R Reuhl; Guang-Yu Yang; Li-Dong Wang; Shou-Lin Wang; Chung S Yang; Xiao-Yang He; Jun-Yan Hong
CYP2A13 in human respiratory tissues and lung cancers: an immunohistochemical study with a new peptide-specific antibody.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(10):1672-6.
2006: Zheng Sun; Sandeep Sood; Ning Li; Divya Ramji; Peiying Yang; Robert A Newman; Chung S Yang; Xiaoxin Chen
Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors.
Carcinogenesis 2006;27(9):1902-8.
2006: Chung S Yang; Joshua D Lambert; Zhe Hou; Jihyeung Ju; Gang Lu; Xinpei Hao
Molecular targets for the cancer preventive activity of tea polyphenols.
Molecular carcinogenesis 2006;45(6):431-5.
2006: Joshua D Lambert; Dou Hwan Kim; Ruijin Zheng; Chung S Yang
Transdermal delivery of (-)-epigallocatechin-3-gallate, a green tea polyphenol, in mice.
The Journal of pharmacy and pharmacology 2006;58(5):599-604.
2006: Hideya Mizuno; Yong-Yeon Cho; Feng Zhu; Wei-Ya Ma; Ann M Bode; Chung S Yang; Chi-Tang Ho; Zigang Dong
Theaflavin-3, 3'-digallate induces epidermal growth factor receptor downregulation.
Molecular carcinogenesis 2006;45(3):204-12.
2006: Chung S Yang; Shengmin Sang; Joshua D Lambert; Zhe Hou; Jihyeung Ju; Gang Lu
Possible mechanisms of the cancer-preventive activities of green tea.
Molecular nutrition & food research 2006;50(2):170-5.
2006: Jungil Hong; Shengmin Sang; Hye-Jin Park; Seok Joo Kwon; Nanjoo Suh; Mou-Tuan Huang; Chi-Tang Ho; Chung S Yang
Modulation of arachidonic acid metabolism and nitric oxide synthesis by garcinol and its derivatives.
Carcinogenesis 2006;27(2):278-86.
2006: Joshua D Lambert; Mao-Jung Lee; Lauren Diamond; Jihyeung Ju; Jungil Hong; Mousumi Bose; Harold L Newmark; Chung S Yang
Dose-dependent levels of epigallocatechin-3-gallate in human colon cancer cells and mouse plasma and tissues.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(1):8-11.
2005: Shengmin Sang; Mao-Jung Lee; Zhe Hou; Chi-Tang Ho; Chung S Yang
Stability of tea polyphenol (-)-epigallocatechin-3-gallate and formation of dimers and epimers under common experimental conditions.
Journal of agricultural and food chemistry 2005;53(24):9478-84.
2005: Jihyeung Ju; Jungil Hong; Jian-nian Zhou; Zui Pan; Mousumi Bose; Jie Liao; Guang-Yu Yang; Ying Ying Liu; Zhe Hou; Yong Lin; Jianjie Ma; Weichung Joe Shih; Adelaide M Carothers; Chung S Yang
Inhibition of intestinal tumorigenesis in Apcmin/+ mice by (-)-epigallocatechin-3-gallate, the major catechin in green tea.
Cancer research 2005;65(22):10623-31.
2005: Shengmin Sang; Zhe Hou; Joshua D Lambert; Chung S Yang
Redox properties of tea polyphenols and related biological activities.
Antioxidants & redox signaling 2005;7(11-12):1704-14.
2005: Shengmin Sang; Joshua D Lambert; Jungil Hong; Shiying Tian; Mao-Jung Lee; Ruth E Stark; Chi-Tang Ho; Chung S Yang
Synthesis and structure identification of thiol conjugates of (-)-epigallocatechin gallate and their urinary levels in mice.
Chemical research in toxicology 2005;18(11):1762-9.
2005: Guoxiang Shen; Changjiang Xu; Rong Hu; MOHIT R JAIN; Sujit Nair; Wen Lin; Chung S Yang; Jefferson Y Chan; Ah-Ng Tony Kong
Comparison of (-)-epigallocatechin-3-gallate elicited liver and small intestine gene expression profiles between C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice.
Pharmaceutical research 2005;22(11):1805-20.
2005: Ming Zhu Fang; Dapeng Chen; Yi Sun; Zhe Jin; Judith K Christman; Chung S Yang
Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(19 Pt 1):7033-41.
2005: Truyen Nguyen; Philip J Sherratt; Paul Nioi; Chung S Yang; Cecil B Pickett
Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1.
The Journal of biological chemistry 2005;280(37):32485-92.
2005: Zhe Hou; Shengmin Sang; Hui You; Mao-Jung Lee; Jungil Hong; Khew-Voon Chin; Chung S Yang
Mechanism of action of (-)-epigallocatechin-3-gallate: auto-oxidation-dependent inactivation of epidermal growth factor receptor and direct effects on growth inhibition in human esophageal cancer KYSE 150 cells.
Cancer research 2005;65(17):8049-56.
2005: Yao-Ping Lu; You-Rong Lou; Jie Liao; Jian-Guo Xie; Qing-Yun Peng; Chung S Yang; Allan H Conney
Administration of green tea or caffeine enhances the disappearance of UVB-induced patches of mutant p53 positive epidermal cells in SKH-1 mice.
Carcinogenesis 2005;26(8):1465-72.
2005: Sandeep Sood; Steven J Shiff; Chung S Yang; Xiaoxin Chen
Selection of topically applied non-steroidal anti-inflammatory drugs for oral cancer chemoprevention.
Oral oncology 2005;41(6):562-7.
2005: Dapeng Chen; Ching Y Wang; Joshua D Lambert; Ni Ai; WILLIAM J WELSH; Chung S Yang
Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: structure-activity relationship and molecular-modeling studies.
Biochemical pharmacology 2005;69(10):1523-31.
2005: Darren N Seril; Jie Liao; Chung S Yang; Guang-Yu Yang
Systemic iron supplementation replenishes iron stores without enhancing colon carcinogenesis in murine models of ulcerative colitis: comparison with iron-enriched diet.
Digestive diseases and sciences 2005;50(4):696-707.
2005: Joshua D Lambert; Dapeng Chen; Ching Y Wang; Ni Ai; Shengmin Sang; Chi-Tang Ho; WILLIAM J WELSH; Chung S Yang
Benzotropolone inhibitors of estradiol methylation: kinetics and in silico modeling studies.
Bioorganic & medicinal chemistry 2005;13(7):2501-7.
2005: Ning Li; Sandeep Sood; Su Wang; Mingzhu Fang; Peng Wang; Zheng Sun; Chung S Yang; Xiaoxin Chen
Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(5):2089-96.
2005: Ming Zhu Fang; Zhe Jin; Yimin Wang; Jie Liao; Guang-Yu Yang; Li-Dong Wang; Chung S Yang
Promoter hypermethylation and inactivation of O(6)-methylguanine-DNA methyltransferase in esophageal squamous cell carcinomas and its reactivation in cell lines.
International journal of oncology 2005;26(3):615-22.
2005: Joshua D Lambert; Joseph E Rice; Jungil Hong; Zhe Hou; Chung S Yang
Synthesis and biological activity of the tea catechin metabolites, M4 and M6 and their methoxy-derivatives.
Bioorganic & medicinal chemistry letters 2005;15(4):873-6.
2005: Chung S Yang; Jie Liao; Guang-Yu Yang; Gary Lu
Inhibition of lung tumorigenesis by tea.
Experimental lung research 2005;31(1):135-44.
2005: Joshua D Lambert; Jungil Hong; Guang-Yu Yang; Jie Liao; Chung S Yang
Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations.
The American journal of clinical nutrition 2005;81(1 Suppl):284S-291S.
2004: Zhe Hou; Joshua D Lambert; Khew-Voon Chin; Chung S Yang
Effects of tea polyphenols on signal transduction pathways related to cancer chemoprevention.
Mutation research 2004;555(1-2):3-19.
2004: Chung S Yang; Jungil Hong; Zhe Hou; Shengmin Sang
Green tea polyphenols: antioxidative and prooxidative effects.
The Journal of nutrition 2004;134(11):3181S.
2004: Xiaoxin Chen; Su Wang; Nan Wu; Sandeep Sood; Peng Wang; Zhe Jin; David G Beer; Thomas J Giordano; Yong Lin; Wei-Chung J Shih; Ronald A Lubet; Chung S Yang
Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(19):6703-9.
2004: Ragini Vittal; Zachariah E Selvanayagam; Yi Sun; Jungil Hong; Fang Liu; Khew-Voon Chin; Chung S Yang
Gene expression changes induced by green tea polyphenol (-)-epigallocatechin-3-gallate in human bronchial epithelial 21BES cells analyzed by DNA microarray.
Molecular cancer therapeutics 2004;3(9):1091-9.
2004: Martha C Kimos; Suna Wang; Andrew Borkowski; Guang-Yu Yang; Chung S Yang; Kellie Perry; Andreea Olaru; Elena Deacu; Anca Sterian; John R Cottrell; John C Papadimitriou; Lopa Sisodia; Florin Selaru; Yuriko Mori; Yan Xu; Jing Yin; John M Abraham; Meltzer Stephen J.
Esophagin and proliferating cell nuclear antigen (PCNA) are biomarkers of human esophageal neoplastic progression.
International journal of cancer. Journal international du cancer 2004;111(3):415-7.
2004: Jungil Hong; Mousumi Bose; Jihyeung Ju; Jae-Ha Ryu; Xiaoxin Chen; Shengmin Sang; Mao-Jung Lee; Chung S Yang
Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase.
Carcinogenesis 2004;25(9):1671-9.
2004: Truyen Nguyen; Chung S Yang; Cecil B Pickett
The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress.
Free radical biology & medicine 2004;37(4):433-41.
2004: Joshua D Lambert; Jungil Hong; Dou Hwan Kim; Vladimir M Mishin; Chung S Yang
Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice.
The Journal of nutrition 2004;134(8):1948-52.
2004: Shengmin Sang; Shiying Tian; Ruth E Stark; Chung S Yang; Chi-Tang Ho
New dibenzotropolone derivatives characterized from black tea using LC/MS/MS.
Bioorganic & medicinal chemistry 2004;12(11):3009-17.
2004: Yinghao Su; Xiaoxin Chen; Michael Klein; Ming Fang; Su Wang; Chung S Yang; Raj K Goyal
Phenotype of columnar-lined esophagus in rats with esophagogastroduodenal anastomosis: similarity to human Barrett's esophagus.
Laboratory investigation; a journal of technical methods and pathology 2004;84(6):753-65.
2004: Ming Zhu Fang; Changgong Liu; Yunlong Song; Guang-Yu Yang; Yan Nie; Jie Liao; Xin Zhao; Yutaka Shimada; Li-Dong Wang; Chung S Yang
Over-expression of gastrin-releasing peptide in human esophageal squamous cell carcinomas.
Carcinogenesis 2004;25(6):865-71.
2004: Marie-Claude Menet; Shengmin Sang; Chung S Yang; Chi-Tang Ho; Robert T Rosen
Analysis of theaflavins and thearubigins from black tea extract by MALDI-TOF mass spectrometry.
Journal of agricultural and food chemistry 2004;52(9):2455-61.
2004: Xiaoxin Chen; Su Wang; Nan Wu; Chung S Yang
Leukotriene A4 hydrolase as a target for cancer prevention and therapy.
Current cancer drug targets 2004;4(3):267-83.
2004: Takashi Hashimoto; Zhiwei He; Wei-Ya Ma; Patricia C Schmid; Ann M Bode; Chung S Yang; Zigang Dong
Caffeine inhibits cell proliferation by G0/G1 phase arrest in JB6 cells.
Cancer research 2004;64(9):3344-9.
2004: Chung S Yang; Khew-Voon Chin; Joshua D Lambert
Cancer chemoprevention by targeting proteasomal degradation: commentary re KA Dragnev et al, Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: implications for combination therapy. Clin Cancer Res, 2004;10:2570-7.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2220-1.
2004: Xiaofeng Meng; Pius Maliakal; Hong Lu; Mao-Jung Lee; Chung S Yang
Urinary and plasma levels of resveratrol and quercetin in humans, mice, and rats after ingestion of pure compounds and grape juice.
Journal of agricultural and food chemistry 2004;52(4):935-42.
2004: Shengmin Sang; Joshua D Lambert; Shiying Tian; Jungil Hong; Zhe Hou; Jae-He Ryu; Ruth E Stark; Robert T Rosen; Mou-Tuan Huang; Chung S Yang; Chi-Tang Ho
Enzymatic synthesis of tea theaflavin derivatives and their anti-inflammatory and cytotoxic activities.
Bioorganic & medicinal chemistry 2004;12(2):459-67.
2004: Jie Liao; Guang-Yu Yang; Eon Sub Park; Xiaofeng Meng; Yuhai Sun; Dongxuan Jia; Darren N Seril; Chung S Yang
Inhibition of lung carcinogenesis and effects on angiogenesis and apoptosis in A/J mice by oral administration of green tea.
Nutrition and cancer 2004;48(1):44-53.
2004: Mao-Jung Lee; Joshua D Lambert; Saileta Prabhu; Xiaofeng Meng; Hong Lu; Pius Maliakal; Chi-Tang Ho; Chung S Yang
Delivery of tea polyphenols to the oral cavity by green tea leaves and black tea extract.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(1):132-7.
2004: Chi-Kwong So; Yan Nie; Yunlong Song; Guang-Yu Yang; Suzie Chen; Caroline Wei; Li-Dong Wang; Norman A Doggett; Chung S Yang
Loss of heterozygosity and internal tandem duplication mutations of the CBP gene are frequent events in human esophageal squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(1 Pt 1):19-27.
2003: Joshua D Lambert; Mao-Jung Lee; Hong Lu; Xiaofeng Meng; Jihyeung Ju Jungil Hong; Darren N Seril; Marc G Sturgill; Chung S Yang
Epigallocatechin-3-gallate is absorbed but extensively glucuronidated following oral administration to mice.
The Journal of nutrition 2003;133(12):4172-7.
2003: Ming Zhu Fang; Yimin Wang; Ni Ai; Zhe Hou; Yi Sun; Hong Lu; WILLIAM J WELSH; Chung S Yang
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
Cancer research 2003;63(22):7563-70.
2003: Yimin Wang; Ming Zhu Fang; Jie Liao; Guang-Yu Yang; Yan Nie; Yunlong Song; Chi So; Xiaochun Xu; Li-Dong Wang; Chung S Yang
Hypermethylation-associated inactivation of retinoic acid receptor beta in human esophageal squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(14):5257-63.
2003: Jungil Hong; Joshua D Lambert; Sung-Hack Lee; Patrick Sinko; Chung S Yang
Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites.
Biochemical and biophysical research communications 2003;310(1):222-7.
2003: Joshua D Lambert; Chung S Yang
Mechanisms of cancer prevention by tea constituents.
The Journal of nutrition 2003;133(10):3262S-3267S.
2003: Philip R Taylor; You-Lin Qiao; Christian C Abnet; Sanford M Dawsey; Chung S Yang; Elaine W Gunter; Wen Wang; William J Blot; Zhi-Wei Dong; Steven D Mark
Prospective study of serum vitamin E levels and esophageal and gastric cancers.
Journal of the National Cancer Institute 2003;95(18):1414-6.
2003: Christian C Abnet; You-Lin Qiao; Sanford M Dawsey; Dennis W Buckman; Chung S Yang; William J Blot; Zhi-Wei Dong; Philip R Taylor; Steven D Mark
Prospective study of serum retinol, beta-carotene, beta-cryptoxanthin, and lutein/zeaxanthin and esophageal and gastric cancers in China.
Cancer causes & control : CCC 2003;14(7):645-55.
2003: Shengmin Sang; Shiying Tian; Hsin Wang; Ruth E Stark; Robert T Rosen; Chung S Yang; Chi-Tang Ho
Chemical studies of the antioxidant mechanism of tea catechins: radical reaction products of epicatechin with peroxyl radicals.
Bioorganic & medicinal chemistry 2003;11(16):3371-8.
2003: Zhiwei He; Wei-Ya Ma; Takashi Hashimoto; Ann M Bode; Chung S Yang; Zigang Dong
Induction of apoptosis by caffeine is mediated by the p53, Bax, and caspase 3 pathways.
Cancer research 2003;63(15):4396-401.
2003: Xiaoxin Chen; Ning Li; Su Wang; Nan Wu; Jungil Hong; Xiaolong Jiao; Mark J Krasna; David G Beer; Chung S Yang
Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin.
Journal of the National Cancer Institute 2003;95(14):1053-61.
2003: Hong Lu; Xiaofeng Meng; Chung S Yang
Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(5):572-9.
2003: Hong Lu; Xiaofeng Meng; Chuan Li; Shengmin Sang; Christopher Patten; Shuqun Sheng; Jungil Hong; Naisheng Bai; Bozena Winnik; Chi-Tang Ho; Chung S Yang
Glucuronides of tea catechins: enzymology of biosynthesis and biological activities.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(4):452-61.
2003: Darren N Seril; Jie Liao; Guang-Yu Yang; Chung S Yang
Oxidative stress and ulcerative colitis-associated carcinogenesis: studies in humans and animal models.
Carcinogenesis 2003;24(3):353-62.
2003: Truyen Nguyen; Philip J Sherratt; HC Huang; Chung S Yang; Cecil B Pickett
Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome.
The Journal of biological chemistry 2003;278(7):4536-41.
2003: Joshua D Lambert; Chung S Yang
Cancer chemopreventive activity and bioavailability of tea and tea polyphenols.
Mutation research 2003;523-524():201-8.
2003: Jihyeung Ju; Yue Liu; Jungil Hong; Mou-Tuan Huang; Allan H Conney; Chung S Yang
Effects of green tea and high-fat diet on arachidonic acid metabolism and aberrant crypt foci formation in an azoxymethane-induced colon carcinogenesis mouse model.
Nutrition and cancer 2003;46(2):172-8.
2002: Jungil Hong; Hong Lu; Xiaofeng Meng; Jae-Ha Ryu; Yukihiko Hara; Chung S Yang
Stability, cellular uptake, biotransformation, and efflux of tea polyphenol (-)-epigallocatechin-3-gallate in HT-29 human colon adenocarcinoma cells.
Cancer research 2002;62(24):7241-6.
2002: Xiaoxin Chen; Ning Li; Su Wang; Jungil Hong; Mingzhu Fang; Joseph Yousselfson; Peiying Yang; Robert A Newman; Ronald A Lubet; Chung S Yang
Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model.
Carcinogenesis 2002;23(12):2095-102.
2002: Mao-Jung Lee; Pius Maliakal; Laishun Chen; Xiaofeng Meng; Flordeliza Y Bondoc; Saileta Prabhu; George Lambert; Sandra Mohr; Chung S Yang
Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(10 Pt 1):1025-32.
2002: Yan Nie; Jie Liao; Xin Zhao; Yunlong Song; Guang-Yu Yang; Li-Dong Wang; Chung S Yang
Detection of multiple gene hypermethylation in the development of esophageal squamous cell carcinoma.
Carcinogenesis 2002;23(10):1713-20.
2002: Yao-Ping Lu; You-Rong Lou; Jian-Guo Xie; Qing-Yun Peng; Jie Liao; Chung S Yang; Mou-Tuan Huang; Allan H Conney
Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12455-60.
2002: Canlan Sun; Jian-Min Yuan; Mao-Jung Lee; Chung S Yang; Yu-Tang Gao; Ronald K Ross; Mimi C Yu
Urinary tea polyphenols in relation to gastric and esophageal cancers: a prospective study of men in Shanghai, China.
Carcinogenesis 2002;23(9):1497-503.
2002: Xiaofeng Meng; Shengmin Sang; Nanqun Zhu; Hong Lu; Shuqun Sheng; Mao-Jung Lee; Chi-Tang Ho; Chung S Yang
Identification and characterization of methylated and ring-fission metabolites of tea catechins formed in humans, mice, and rats.
Chemical research in toxicology 2002;15(8):1042-50.
2002: Ning Li; Xiaoxin Chen; Jie Liao; Guang-Yu Yang; Su Wang; Youssef Josephson; Chi Han; Junshi Chen; Mou-Tuan Huang; Chung S Yang
Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamsters by tea and curcumin.
Carcinogenesis 2002;23(8):1307-13.
2002: Shengmin Sang; Xiaofang Cheng; Ruth E Stark; Robert T Rosen; Chung S Yang; Chi-Tang Ho
Chemical studies on antioxidant mechanism of tea catechins: analysis of radical reaction products of catechin and epicatechin with 2,2-diphenyl-1-picrylhydrazyl.
Bioorganic & medicinal chemistry 2002;10(7):2233-7.
2002: Darren N Seril; Jie Liao; Kwok-Lam K Ho; Chung S Yang; Guang-Yu Yang
Inhibition of chronic ulcerative colitis-associated colorectal adenocarcinoma development in a murine model by N-acetylcysteine.
Carcinogenesis 2002;23(6):993-1001.
2002: Darren N Seril; Jie Liao; Kwok-Lam K Ho; Asim Warsi; Chung S Yang; Guang-Yu Yang
Dietary iron supplementation enhances DSS-induced colitis and associated colorectal carcinoma development in mice.
Digestive diseases and sciences 2002;47(6):1266-78.
2002: Chung S Yang; Pius Maliakal; Xiaofeng Meng
Inhibition of carcinogenesis by tea.
Annual review of pharmacology and toxicology 2002;42():25-54.
2002: Xiaoxin Chen; Yu Ding; Chang-Gong Liu; Samer Mikhail; Chung S Yang
Overexpression of glucose-regulated protein 94 (Grp94) in esophageal adenocarcinomas of a rat surgical model and humans.
Carcinogenesis 2002;23(1):123-30.
2001: J Hong; TJ Smith; Chi-Tang Ho; D A August; Chung S Yang
Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues.
Biochemical pharmacology 2001;62(9):1175-83.
2001: Allan Hildesheim; Mustafa Dosemeci; C C Chan; Chien-Jen Chen; Yu-Juen Cheng; Mow-Ming Hsu; I-How Chen; Beth F Mittl; Brenda Sun; Paul H Levine; Jen-Yang Chen; Louise A Brinton; Chung S Yang
Occupational exposure to wood, formaldehyde, and solvents and risk of nasopharyngeal carcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(11):1145-53.
2001: Yan Nie; G y Yang; Yunlong Song; Xin Zhao; C So; Jie Liao; Li-Dong Wang; Chung S Yang
DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas.
Carcinogenesis 2001;22(10):1615-23.
2001: JY Chung; J O Park; H Phyu; Z Dong; Chung S Yang
Mechanisms of inhibition of the Ras-MAP kinase signaling pathway in 30.7b Ras 12 cells by tea polyphenols (-)-epigallocatechin-3-gallate and theaflavin-3,3'-digallate.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(11):2022-4.
2001: Chung S Yang; Saileta Prabhu; JM Landau
Prevention of carcinogenesis by tea polyphenols.
Drug metabolism reviews 2001;33(3-4):237-53.
2001: Xiaoxin Chen; Chung S Yang
Esophageal adenocarcinoma: a review and perspectives on the mechanism of carcinogenesis and chemoprevention.
Carcinogenesis 2001;22(8):1119-29.
2001: Yao-Ping Lu; You-Rong Lou; Y Lin; W J Shih; Mou-Tuan Huang; Chung S Yang; Allan H Conney
Inhibitory effects of orally administered green tea, black tea, and caffeine on skin carcinogenesis in mice previously treated with ultraviolet B light (high-risk mice): relationship to decreased tissue fat.
Cancer research 2001;61(13):5002-9.
2001: Wei-Cheng You; Yun-Sheng Chang; J Heinrich; Jun-Ling Ma; Wei-dong Liu; Luoping Zhang; Linda Morris Brown; Chung S Yang; Mitchell H Gail; Joseph Fraumeni; Guang-Wei Xu
An intervention trial to inhibit the progression of precancerous gastric lesions: compliance, serum micronutrients and S-allyl cysteine levels, and toxicity.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2001;10(3):257-63.
2001: Chuan Li; Xiaofeng Meng; Bozena Winnik; Mao-Jung Lee; Hong Lu; Shuqun Sheng; B Buckley; Chung S Yang
Analysis of urinary metabolites of tea catechins by liquid chromatography/electrospray ionization mass spectrometry.
Chemical research in toxicology 2001;14(6):702-7.
2001: Chung S Yang; S K Chhabra; JY Hong; TJ Smith
Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic.
The Journal of nutrition 2001;131(3s):1041S-5S.
2001: Chung S Yang
Inhibition of carcinogenesis and toxicity by dietary constituents.
Advances in experimental medicine and biology 2001;500():541-50.
2001: Chung S Yang; Guang-Yu Yang; JY Chung; Mao-Jung Lee; Chuan Li
Tea and tea polyphenols in cancer prevention.
Advances in experimental medicine and biology 2001;492():39-53.
2001: Chung S Yang; J M Landau; Mou-Tuan Huang; Harold L Newmark
Inhibition of carcinogenesis by dietary polyphenolic compounds.
Annual review of nutrition 2001;21():381-406.
2000: Wei-Cheng You; Luoping Zhang; Mitchell H Gail; Yun-Sheng Chang; Wei-dong Liu; Jun-Ling Ma; Ji-You Li; Mao-lin Jin; Yan-Ren Hu; Chung S Yang; Martin Blaser; P Correa; William J Blot; Joseph Fraumeni; Guang-Wei Xu
Gastric dysplasia and gastric cancer: Helicobacter pylori, serum vitamin C, and other risk factors.
Journal of the National Cancer Institute 2000;92(19):1607-12.
2000: Chung S Yang; J M Landau
Effects of tea consumption on nutrition and health.
The Journal of nutrition 2000;130(10):2409-12.
2000: Xiaoxin Chen; S S Mikhail; Y W Ding; G y Yang; Flordeliza Y Bondoc; Chung S Yang
Effects of vitamin E and selenium supplementation on esophageal adenocarcinogenesis in a surgical model with rats.
Carcinogenesis 2000;21(8):1531-6.
2000: Mary H Ward; W H Pan; Yu-Juen Cheng; F H Li; Louise A Brinton; Chien-Jen Chen; Mow-Ming Hsu; I-How Chen; P H Levine; Chung S Yang; Allan Hildesheim
Dietary exposure to nitrite and nitrosamines and risk of nasopharyngeal carcinoma in Taiwan.
International journal of cancer. Journal international du cancer 2000;86(5):603-9.
2000: Nanqun Zhu; T C Huang; Y Yu; E J LaVoie; Chung S Yang; Chi-Tang Ho
Identification of oxidation products of (-)-epigallocatechin gallate and (-)-epigallocatechin with H(2)O(2).
Journal of agricultural and food chemistry 2000;48(4):979-81.
2000: Yuyang Christine Cai; Guang-Yu Yang; Yan Nie; Li-Dong Wang; Xin Zhao; Y L Song; DN Seril; Jie Liao; EP Xing; Chung S Yang
Molecular alterations of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53.
Carcinogenesis 2000;21(4):683-9.
2000: Chuan Li; Mao-Jung Lee; Shuqun Sheng; Xiaofeng Meng; Saileta Prabhu; Bozena Winnik; B Huang; JY Chung; S Yan; Chi-Tang Ho; Chung S Yang
Structural identification of two metabolites of catechins and their kinetics in human urine and blood after tea ingestion.
Chemical research in toxicology 2000;13(3):177-84.
2000: Chung S Yang; JY Chung; Guang-Yu Yang; S K Chhabra; Mao-Jung Lee
Tea and tea polyphenols in cancer prevention.
The Journal of nutrition 2000;130(2S Suppl):472S-478S.
2000: Chung S Yang
Vitamin nutrition and gastroesophageal cancer.
The Journal of nutrition 2000;130(2S Suppl):338S-339S.
2000: Xiaoxin Chen; Y W Ding; G y Yang; Flordeliza Y Bondoc; Mao-Jung Lee; Chung S Yang
Oxidative damage in an esophageal adenocarcinoma model with rats.
Carcinogenesis 2000;21(2):257-63.
2000: S Kim; Mao-Jung Lee; J Hong; Chuan Li; TJ Smith; Guang-Yu Yang; DN Seril; Chung S Yang
Plasma and tissue levels of tea catechins in rats and mice during chronic consumption of green tea polyphenols.
Nutrition and cancer 2000;37(1):41-8.
1999: EP Xing; Yan Nie; Yunlong Song; Guang-Yu Yang; Yuyang Christine Cai; Li-Dong Wang; Chung S Yang
Mechanisms of inactivation of p14ARF, p15INK4b, and p16INK4a genes in human esophageal squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10):2704-13.
1999: JY Hong; YY Wang; Flordeliza Y Bondoc; M Lee; Chung S Yang; WY Hu; J Pan
Metabolism of methyl tert-butyl ether and other gasoline ethers by human liver microsomes and heterologously expressed human cytochromes P450: identification of CYP2A6 as a major catalyst.
Toxicology and applied pharmacology 1999;160(1):43-8.
1999: JY Chung; C Huang; Xiaofeng Meng; Z Dong; Chung S Yang
Inhibition of activator protein 1 activity and cell growth by purified green tea and black tea polyphenols in H-ras-transformed cells: structure-activity relationship and mechanisms involved.
Cancer research 1999;59(18):4610-7.
1999: Xiaoxin Chen; G y Yang; W Y Ding; Flordeliza Y Bondoc; SK Curtis; Chung S Yang
An esophagogastroduodenal anastomosis model for esophageal adenocarcinogenesis in rats and enhancement by iron overload.
Carcinogenesis 1999;20(9):1801-8.
1999: Flordeliza Y Bondoc; Z Bao; WY Hu; F J Gonzalez; Yihan Wang; Chung S Yang; JY Hong
Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice.
Biochemical pharmacology 1999;58(3):461-3.
1999: EP Xing; Guang-Yu Yang; Li-Dong Wang; S T Shi; Chung S Yang
Loss of heterozygosity of the Rb gene correlates with pRb protein expression and associates with p53 alteration in human esophageal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(5):1231-40.
1999: S T Shi; Guang-Yu Yang; Li-Dong Wang; Z Xue; B Feng; W Ding; EP Xing; Chung S Yang
Role of p53 gene mutations in human esophageal carcinogenesis: results from immunohistochemical and mutation analyses of carcinomas and nearby non-cancerous lesions.
Carcinogenesis 1999;20(4):591-7.
1999: Chung S Yang; S Kim; Guang-Yu Yang; Mao-Jung Lee; Jie Liao; JY Chung; Chi-Tang Ho
Inhibition of carcinogenesis by tea: bioavailability of tea polyphenols and mechanisms of actions.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1999;220(4):213-7.
1999: JY Hong; YY Wang; Flordeliza Y Bondoc; Chung S Yang; F J Gonzalez; Z Pan; C D Cokonis; WY Hu; Z Bao
Metabolism of methyl tert-butyl ether and other gasoline ethers in mouse liver microsomes lacking cytochrome P450 2E1.
Toxicology letters 1999;105(1):83-8.
1999: L Chen; JY Hong; E So; A H Hussin; W F Cheng; Chung S Yang
Decrease of hepatic catalase level by treatment with diallyl sulfide and garlic homogenates in rats and mice.
Journal of biochemical and molecular toxicology 1999;13(3-4):127-34.
1999: Chung S Yang; Mao-Jung Lee; Laishun Chen
Human salivary tea catechin levels and catechin esterase activities: implication in human cancer prevention studies.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(1):83-9.
1999: EP Xing; Yan Nie; Li-Dong Wang; Guang-Yu Yang; Chung S Yang
Aberrant methylation of p16INK4a and deletion of p15INK4b are frequent events in human esophageal cancer in Linxian, China.
Carcinogenesis 1999;20(1):77-84.
1998: S R Goldstein; Guang-Yu Yang; Xiaoxin Chen; SK Curtis; Chung S Yang
Studies of iron deposits, inducible nitric oxide synthase and nitrotyrosine in a rat model for esophageal adenocarcinoma.
Carcinogenesis 1998;19(8):1445-9.
1998: Chung S Yang; Guang-Yu Yang; JM Landau; S Kim; Jie Liao
Tea and tea polyphenols inhibit cell hyperproliferation, lung tumorigenesis, and tumor progression.
Experimental lung research 1998;24(4):629-39.
1998: TJ Smith; A Liao; Li-Dong Wang; Guang-Yu Yang; S Starcic; M A Philbert; Chung S Yang
Characterization of xenobiotic-metabolizing enzymes and nitrosamine metabolism in the human esophagus.
Carcinogenesis 1998;19(4):667-72.
1998: Guang-Yu Yang; Jie Liao; KYOUNGHYUN Kim; E J Yurkow; Chung S Yang
Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols.
Carcinogenesis 1998;19(4):611-6.
1998: Chung S Yang; Laishun Chen; Mao-Jung Lee; D Balentine; M C Kuo; S P Schantz
Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(4):351-4.
1998: JM Landau; Z Y Wang; Guang-Yu Yang; W Ding; Chung S Yang
Inhibition of spontaneous formation of lung tumors and rhabdomyosarcomas in A/J mice by black and green tea.
Carcinogenesis 1998;19(3):501-7.
1997: Guang-Yu Yang; Z Liu; DN Seril; Jie Liao; W Ding; S Kim; Flordeliza Y Bondoc; Chung S Yang
Black tea constituents, theaflavins, inhibit 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice.
Carcinogenesis 1997;18(12):2361-5.
1997: JY Hong; YY Wang; Flordeliza Y Bondoc; Chung S Yang; M Lee; W Q Huang
Rat olfactory mucosa displays a high activity in metabolizing methyl tert-butyl ether and other gasoline ethers.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1997;40(2):205-10.
1997: S R Goldstein; Guang-Yu Yang; SK Curtis; Kenneth R Reuhl; B C Liu; S S Mirvish; Harold L Newmark; Chung S Yang
Development of esophageal metaplasia and adenocarcinoma in a rat surgical model without the use of a carcinogen.
Carcinogenesis 1997;18(11):2265-70.
1997: Guang-Yu Yang; Z Zhang; Jie Liao; DN Seril; L Wang; S Goldstein; Chung S Yang
Immunohistochemical studies on Waf1p21, p16, pRb and p53 in human esophageal carcinomas and neighboring epithelia from a high-risk area in northern China.
International journal of cancer. Journal international du cancer 1997;72(5):746-51.
1997: Laishun Chen; Mao-Jung Lee; H Li; Chung S Yang
Absorption, distribution, elimination of tea polyphenols in rats.
Drug metabolism and disposition: the biological fate of chemicals 1997;25(9):1045-50.
1997: Allan Hildesheim; Lucy M Anderson; Chien-Jen Chen; Yu-Juen Cheng; Louise A Brinton; A K Daly; Carl D Reed; I-How Chen; Neil E Caporaso; Mow-Ming Hsu; J Y Chen; Jeffrey R Idle; Robert N Hoover; Chung S Yang; Saranjit K Chhabra
CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan.
Journal of the National Cancer Institute 1997;89(16):1207-12.
1997: TJ Smith; A M Liao; Y Liu; A B Jones; L M Anderson; Chung S Yang
Enzymes involved in the bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in patas monkey lung and liver microsomes.
Carcinogenesis 1997;18(8):1577-84.
1997: Chung S Yang; M J Lee; L Chen; Guang-Yu Yang
Polyphenols as inhibitors of carcinogenesis.
Environmental health perspectives 1997;105 Suppl 4():971-6.
1997: J Y Hong; Chung S Yang
Genetic polymorphism of cytochrome P450 as a biomarker of susceptibility to environmental toxicity.
Environmental health perspectives 1997;105 Suppl 4():759-62.
1997: Y Li; E J Wang; L Chen; A P Stein; Kenneth R Reuhl; Chung S Yang
Effects of phenethyl isothiocyanate on acetaminophen metabolism and hepatotoxicity in mice.
Toxicology and applied pharmacology 1997;144(2):306-14.
1997: Y Tan; C J Patten; T Smith; Chung S Yang
Competitive interactions between cytochromes P450 2A6 and 2E1 for NADPH-cytochrome P450 oxidoreductase in the microsomal membranes produced by a baculovirus expression system.
Archives of biochemistry and biophysics 1997;342(1):82-91.
1997: Guang-Yu Yang; Z Y Wang; S Kim; Jie Liao; DN Seril; X Chen; TJ Smith; Chung S Yang
Characterization of early pulmonary hyperproliferation and tumor progression and their inhibition by black tea in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model with A/J mice.
Cancer research 1997;57(10):1889-94.
1997: Y Tan; S P White; S R Paranawithana; Chung S Yang
A hypothetical model for the active site of human cytochrome P4502E1.
Xenobiotica; the fate of foreign compounds in biological systems 1997;27(3):287-99.
1997: JY Hong; Chung S Yang; M Lee; YY Wang; W Q Huang; Y Tan; C J Patten; Flordeliza Y Bondoc
Role of cytochromes P450 in the metabolism of methyl tert-butyl ether in human livers.
Archives of toxicology 1997;71(4):266-9.
1996: L Chen; S N Mohr; Chung S Yang
Decrease of plasma and urinary oxidative metabolites of acetaminophen after consumption of watercress by human volunteers.
Clinical pharmacology and therapeutics 1996;60(6):651-60.
1996: Mong-Heng Wang; C J Patten; Guang-Yu Yang; S R Paranawithana; Y Tan; Chung S Yang
Expression and coupling of human cytochrome P450 2E1 and NADPH-cytochrome P450 oxidoreductase in dual expression and co-infection systems with baculovirus in insect cells.
Archives of biochemistry and biophysics 1996;334(2):380-8.
1996: Jennifer Hu; J S Yoo; M Lin; E J Wang; Chung S Yang
Protective effects of diallyl sulfide on acetaminophen-induced toxicities.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1996;34(10):963-9.
1996: S T Shi; B Feng; Guang-Yu Yang; Li-Dong Wang; Chung S Yang
Immunohistoselective sequencing (IHSS) of p53 tumor suppressor gene in human oesophageal precancerous lesions.
Carcinogenesis 1996;17(10):2131-6.
1996: Laishun Chen; Flordeliza Y Bondoc; Mao-Jung Lee; A H Hussin; P E Thomas; Chung S Yang
Caffeine induces cytochrome P4501A2: induction of CYP1A2 by tea in rats.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(5):529-33.
1996: TJ Smith; Z Guo; F P Guengerich; Chung S Yang
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate.
Carcinogenesis 1996;17(4):809-13.
1996: Li-Dong Wang; Q Zhou; JY Hong; S L Qiu; Chung S Yang
p53 protein accumulation and gene mutations in multifocal esophageal precancerous lesions from symptom free subjects in a high incidence area for esophageal carcinoma in Henan, China.
Cancer 1996;77(7):1244-9.
1996: Chung S Yang; Barbara C Pence; Michael J Wargovich; J M Landau
Diet, nutrition, and cancer prevention. Research opportunities, approaches, and pitfalls.
Advances in experimental medicine and biology 1996;401():231-8.
1996: Chung S Yang; Laishun Chen; Mao-Jung Lee; J M Landau
Effects of tea on carcinogenesis in animal models and humans.
Advances in experimental medicine and biology 1996;401():51-61.
1996: M C Lin; E J Wang; C Patten; Mao-Jung Lee; F Xiao; Kenneth R Reuhl; Chung S Yang
Protective effect of diallyl sulfone against acetaminophen-induced hepatotoxicity in mice.
Journal of biochemical toxicology 1996;11(1):11-20.
1996: Chung S Yang; TJ Smith
Mechanisms of nitrosamine bioactivation and carcinogenesis.
Advances in experimental medicine and biology 1996;387():385-94.
1996: L Chen; Chung S Yang
Effects of cytochrome P450 2E1 modulators on the pharmacokinetics of chlorzoxazone and 6-hydroxychlorzoxazone in rats.
Life sciences 1996;58(18):1575-85.
1996: E J Wang; Y Li; M Lin; L Chen; A P Stein; Kenneth R Reuhl; Chung S Yang
Protective effects of garlic and related organosulfur compounds on acetaminophen-induced hepatotoxicity in mice.
Toxicology and applied pharmacology 1996;136(1):146-54.
1995: TJ Smith; G D Stoner; Chung S Yang
Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
Cancer research 1995;55(23):5566-73.
1995: K Cui; Q Ma; A Y Lu; Chung S Yang
Roles of histidine-194, aspartate-163, and a glycine-rich sequence of NAD(P)H:quinone oxidoreductase in the interaction with nicotinamide coenzymes.
Archives of biochemistry and biophysics 1995;323(2):265-73.
1995: TJ Smith; JY Hong; Z Y Wang; Chung S Yang
How can carcinogenesis be inhibited?
Annals of the New York Academy of Sciences 1995;768():82-90.
1995: Z Y Wang; Li-Dong Wang; Mao-Jung Lee; Chi-Tang Ho; Mou-Tuan Huang; Allan H Conney; Chung S Yang
Inhibition of N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in rats by green and black tea.
Carcinogenesis 1995;16(9):2143-8.
1995: Mao-Jung Lee; Z Y Wang; H Li; Laishun Chen; Y Sun; S Gobbo; D A Balentine; Chung S Yang
Analysis of plasma and urinary tea polyphenols in human subjects.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1995;4(4):393-9.
1995: Mong-Heng Wang; David Wade; L Chen; S White; Chung S Yang
Probing the active sites of rat and human cytochrome P450 2E1 with alcohols and carboxylic acids.
Archives of biochemistry and biophysics 1995;317(1):299-304.
1995: K Cui; A Y Lu; Chung S Yang
Subunit functional studies of NAD(P)H:quinone oxidoreductase with a heterodimer approach.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(4):1043-7.
1994: L Chen; M Lee; JY Hong; W Huang; E Wang; Chung S Yang
Relationship between cytochrome P450 2E1 and acetone catabolism in rats as studied with diallyl sulfide as an inhibitor.
Biochemical pharmacology 1994;48(12):2199-205.
1994: Li-Dong Wang; S T Shi; Q Zhou; S Goldstein; JY Hong; P Shao; S L Qiu; Chung S Yang
Changes in p53 and cyclin D1 protein levels and cell proliferation in different stages of human esophageal and gastric-cardia carcinogenesis.
International journal of cancer. Journal international du cancer 1994;59(4):514-9.
1994: S T Shi; Z Y Wang; TJ Smith; JY Hong; W F Chen; Chi-Tang Ho; Chung S Yang
Effects of green tea and black tea on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation, DNA methylation, and lung tumorigenesis in A/J mice.
Cancer research 1994;54(17):4641-7.
1994: H Gao; Li-Dong Wang; Q Zhou; JY Hong; T Y Huang; Chung S Yang
p53 tumor suppressor gene mutation in early esophageal precancerous lesions and carcinoma among high-risk populations in Henan, China.
Cancer research 1994;54(16):4342-6.
1994: Z Y Wang; Mou-Tuan Huang; You-Rong Lou; Jian-Guo Xie; K R Reuhl; Harold L Newmark; Chi-Tang Ho; Chung S Yang; Allan H Conney
Inhibitory effects of black tea, green tea, decaffeinated black tea, and decaffeinated green tea on ultraviolet B light-induced skin carcinogenesis in 7,12-dimethylbenz[a]anthracene-initiated SKH-1 mice.
Cancer research 1994;54(13):3428-35.
1994: Y Li; E Wang; C J Patten; Laishun Chen; Chung S Yang
Effects of flavonoids on cytochrome P450-dependent acetaminophen metabolism in rats and human liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 1994;22(4):566-71.
1994: Chung S Yang; TJ Smith; JY Hong
Cytochrome P-450 enzymes as targets for chemoprevention against chemical carcinogenesis and toxicity: opportunities and limitations.
Cancer research 1994;54(7 Suppl):1982s-1986s.
1994: Chung S Yang; Z Y Wang; JY Hong
Inhibition of tumorigenesis by chemicals from garlic and tea.
Advances in experimental medicine and biology 1994;354():113-22.
1993: Jennifer Hu; Mao-Jung Lee; M Vapiwala; Kenneth R Reuhl; P E Thomas; Chung S Yang
Sex-related differences in mouse renal metabolism and toxicity of acetaminophen.
Toxicology and applied pharmacology 1993;122(1):16-26.
1993: TJ Smith; Z Guo; C Li; S M Ning; P E Thomas; Chung S Yang
Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate.
Cancer research 1993;53(14):3276-82.
1993: Chung S Yang; Z Y Wang
Tea and cancer.
Journal of the National Cancer Institute 1993;85(13):1038-49.
1993: C J Patten; P E Thomas; R L Guy; M Lee; F J Gonzalez; F P Guengerich; Chung S Yang
Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics.
Chemical research in toxicology 1993;6(4):511-8.
1993: J Pan; JY Hong; D Li; E G Schuetz; P S Guzelian; W Huang; Chung S Yang
Regulation of cytochrome P450 2B1/2 genes by diallyl sulfone, disulfiram, and other organosulfur compounds in primary cultures of rat hepatocytes.
Biochemical pharmacology 1993;45(11):2323-9.
1993: Z Guo; TJ Smith; E Wang; K I Eklind; Fung-Lung Chung; Chung S Yang
Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice.
Carcinogenesis 1993;14(6):1167-73.
1993: J Pan; JY Hong; B L Ma; S M Ning; S R Paranawithana; Chung S Yang
Transcriptional activation of cytochrome P450 2B1/2 genes in rat liver by diallyl sulfide, a compound derived from garlic.
Archives of biochemistry and biophysics 1993;302(2):337-42.
1993: Li-Dong Wang; JY Hong; S L Qiu; H Gao; Chung S Yang
Accumulation of p53 protein in human esophageal precancerous lesions: a possible early biomarker for carcinogenesis.
Cancer research 1993;53(8):1783-7.
1993: Michael A Lea; Q Xiao; A K Sadhukhan; S Cottle; Z Y Wang; Chung S Yang
Inhibitory effects of tea extracts and (-)-epigallocatechin gallate on DNA synthesis and proliferation of hepatoma and erythroleukemia cells.
Cancer letters 1993;68(2-3):231-6.
1993: Li-Dong Wang; S L Qiu; G R Yang; M Lipkin; H L Newmark; Chung S Yang
A randomized double-blind intervention study on the effect of calcium supplementation on esophageal precancerous lesions in a high-risk population in China.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1993;2(1):71-8.
1992: Z Guo; TJ Smith; E Wang; N Sadrieh; Q Ma; P E Thomas; Chung S Yang
Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabolizing enzymes and nitrosamine metabolism in rats.
Carcinogenesis 1992;13(12):2205-10.
1992: Z Y Wang; Mou-Tuan Huang; Chi-Tang Ho; R Chang; W Ma; T Ferraro; K R Reuhl; Chung S Yang; Allan H Conney
Inhibitory effect of green tea on the growth of established skin papillomas in mice.
Cancer research 1992;52(23):6657-65.
1992: C J Patten; H Ishizaki; T Aoyama; M Lee; S M Ning; W Huang; F J Gonzalez; Chung S Yang
Catalytic properties of the human cytochrome P450 2E1 produced by cDNA expression in mammalian cells.
Archives of biochemistry and biophysics 1992;299(1):163-71.
1992: J Pan; JY Hong; Chung S Yang
Post-transcriptional regulation of mouse renal cytochrome P450 2E1 by testosterone.
Archives of biochemistry and biophysics 1992;299(1):110-5.
1992: Q Ma; K Cui; F Xiao; A Y Lu; Chung S Yang
Identification of a glycine-rich sequence as an NAD(P)H-binding site and tyrosine 128 as a dicumarol-binding site in rat liver NAD(P)H:quinone oxidoreductase by site-directed mutagenesis.
The Journal of biological chemistry 1992;267(31):22298-304.
1992: J Y Hong; X Ding; T J Smith; M J Coon; Chung S Yang
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific carcinogen, by rabbit nasal microsomes and cytochrome P450s NMa and NMb.
Carcinogenesis 1992;13(11):2141-4.
1992: Y Li; S R Paranawithana; J S Yoo; S M Ning; B L Ma; Mao-Jung Lee; G T Liu; Chung S Yang
Induction of liver microsomal cytochrome P-450 2B1 by dimethyl diphenyl bicarboxylate in rats.
Zhongguo yao li xue bao = Acta pharmacologica Sinica 1992;13(6):485-90.
1992: Z Guo; TJ Smith; P E Thomas; Chung S Yang
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by inducible and constitutive cytochrome P450 enzymes in rats.
Archives of biochemistry and biophysics 1992;298(1):279-86.
1992: Chung S Yang; H Ishizaki
Deuterium isotope effect on the metabolism of N-nitrosodimethylamine and related compounds by cytochrome P4502E1.
Xenobiotica; the fate of foreign compounds in biological systems 1992;22(9-10):1165-73.
1992: TJ Smith; Z Guo; JY Hong; S M Ning; P E Thomas; Chung S Yang
Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa.
Carcinogenesis 1992;13(8):1409-14.
1992: J S Yoo; TJ Smith; S M Ning; Mao-Jung Lee; P E Thomas; Chung S Yang
Modulation of the levels of cytochromes P450 in rat liver and lung by dietary lipid.
Biochemical pharmacology 1992;43(12):2535-42.
1992: Mou-Tuan Huang; Chi-Tang Ho; Z Y Wang; T Ferraro; T Finnegan-Olive; You-Rong Lou; J M Mitchell; Jeffrey D Laskin; H Newmark; Chung S Yang
Inhibitory effect of topical application of a green tea polyphenol fraction on tumor initiation and promotion in mouse skin.
Carcinogenesis 1992;13(6):947-54.
1992: Allan H Conney; Z Y Wang; Mou-Tuan Huang; Chi-Tang Ho; Chung S Yang
Inhibitory effect of green tea on tumorigenesis by chemicals and ultraviolet light.
Preventive medicine 1992;21(3):361-9.
1992: JY Hong; Z Y Wang; TJ Smith; S Zhou; S Shi; J Pan; Chung S Yang
Inhibitory effects of diallyl sulfide on the metabolism and tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mouse lung.
Carcinogenesis 1992;13(5):901-4.
1992: Q Ma; K Cui; R W Wang; A Y Lu; Chung S Yang
Site-directed mutagenesis of rat liver NAD(P)H: quinone oxidoreductase: roles of lysine 76 and cysteine 179.
Archives of biochemistry and biophysics 1992;294(2):434-9.
1992: Z Y Wang; JY Hong; Mou-Tuan Huang; K R Reuhl; Allan H Conney; Chung S Yang
Inhibition of N-nitrosodiethylamine- and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorigenesis in A/J mice by green tea and black tea.
Cancer research 1992;52(7):1943-7.
1992: TJ Smith; Z Guo; F J Gonzalez; F P Guengerich; G D Stoner; Chung S Yang
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells.
Cancer research 1992;52(7):1757-63.
1992: Z Y Wang; Mou-Tuan Huang; T Ferraro; C Q Wong; You-Rong Lou; K Reuhl; M Iatropoulos; Chung S Yang; Allan H Conney
Inhibitory effect of green tea in the drinking water on tumorigenesis by ultraviolet light and 12-O-tetradecanoylphorbol-13-acetate in the skin of SKH-1 mice.
Cancer research 1992;52(5):1162-70.
1992: Chung S Yang; J F Brady; JY Hong
Dietary effects on cytochromes P450, xenobiotic metabolism, and toxicity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992;6(2):737-44.
1991: Z Guo; TJ Smith; H Ishizaki; Chung S Yang
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytochrome P450IIB1 in a reconstituted system.
Carcinogenesis 1991;12(12):2277-82.
1991: J F Brady; H Ishizaki; Jon M Fukuto; M C Lin; A Fadel; J M Gapac; Chung S Yang
Inhibition of cytochrome P-450 2E1 by diallyl sulfide and its metabolites.
Chemical research in toxicology 1991;4(6):642-7.
1991: Z Guo; TJ Smith; P E Thomas; Chung S Yang
Metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone as measured by DNA alkylation in vitro and its inhibition by isothiocyanates.
Cancer research 1991;51(18):4798-803.
1991: J S Yoo; S M Ning; Carol B Pantuck; E J Pantuck; Chung S Yang
Regulation of hepatic microsomal cytochrome P450IIE1 level by dietary lipids and carbohydrates in rats.
The Journal of nutrition 1991;121(7):959-65.
1991: Chung S Yang; H Ishizaki; Mao-Jung Lee; David Wade; A Fadel
Deuterium isotope effect in the interaction of N-nitrosodimethylamine, ethanol, and related compounds with cytochrome P-450IIE1.
Chemical research in toxicology 1991;4(4):408-13.
1991: J F Brady; F Xiao; Mong-Heng Wang; Y Li; S M Ning; J M Gapac; Chung S Yang
Effects of disulfiram on hepatic P450IIE1, other microsomal enzymes, and hepatotoxicity in rats.
Toxicology and applied pharmacology 1991;108(2):366-73.
1991: JY Hong; T Smith; Mao-Jung Lee; W S Li; B L Ma; S M Ning; J F Brady; P E Thomas; Chung S Yang
Metabolism of carcinogenic nitrosamines by rat nasal mucosa and the effect of diallyl sulfide.
Cancer research 1991;51(5):1509-14.
1991: T A Chepiga; Chung S Yang; R Snyder
Benzene metabolism by two purified, reconstituted rat hepatic mixed function oxidase systems.
Advances in experimental medicine and biology 1991;283():261-5.
1991: Q A Ma; R Wang; A Y Lu; Chung S Yang
Expression of a cDNA encoding rat liver DT-diaphorase in Escherichia coli.
Advances in experimental medicine and biology 1991;283():323-7.
1991: J S Yoo; H Ishizaki; Chung S Yang
Enzyme kinetics of N-nitrosodimethylamine demethylase in rodents and humans.
IARC scientific publications 1991;(105):366-9.
1991: Chung S Yang; T Smith; H Ishizaki; JY Hong
Enzyme mechanisms in the metabolism of nitrosamines.
IARC scientific publications 1991;(105):265-74.
1991: Chung S Yang; C J Patten; H Ishizaki; J S Yoo
Induction, purification, and characterization of cytochrome P450IIE.
Methods in enzymology 1991;206():595-603.
1990: Jennifer Hu; W B Rhoten; Chung S Yang
Mouse renal cytochrome P450IIE1: immunocytochemical localization, sex-related difference and regulation by testosterone.
Biochemical pharmacology 1990;40(12):2597-602.
1990: J S Yoo; H Ishizaki; Chung S Yang
Roles of cytochrome P450IIE1 in the dealkylation and denitrosation of N-nitrosodimethylamine and N-nitrosodiethylamine in rat liver microsomes.
Carcinogenesis 1990;11(12):2239-43.
1990: J S Yoo; JY Hong; S M Ning; Chung S Yang
Roles of dietary corn oil in the regulation of cytochromes P450 and glutathione S-transferases in rat liver.
The Journal of nutrition 1990;120(12):1718-26.
1990: TJ Smith; Z Y Guo; P E Thomas; Fung-Lung Chung; M A Morse; K Elkind; Chung S Yang
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates.
Cancer research 1990;50(21):6817-22.
1990: Larry K Keefer; M B Kroeger-Koepke; H Ishizaki; Christopher J Michejda; Joseph E Saavedra; Joseph A Hrabie; Chung S Yang; P P Roller
Stereoselectivity in the microsomal conversion of N-nitrosodimethylamine to formaldehyde.
Chemical research in toxicology 1990;3(6):540-4.
1990: JY Hong; S M Ning; B L Ma; Mao-Jung Lee; J M Pan; Chung S Yang
Roles of pituitary hormones in the regulation of hepatic cytochrome P450IIE1 in rats and mice.
Archives of biochemistry and biophysics 1990;281(1):132-8.
1990: Li-Dong Wang; M Lipkin; S L Qui; G R Yang; Chung S Yang; H L Newmark
Labeling index and labeling distribution of cells in esophageal epithelium of individuals at increased risk for esophageal cancer in Huixian, China.
Cancer research 1990;50(9):2651-3.
1990: H Ishizaki; J F Brady; S M Ning; Chung S Yang
Effect of phenethyl isothiocyanate on microsomal N-nitrosodimethylamine metabolism and other monooxygenase activities.
Xenobiotica; the fate of foreign compounds in biological systems 1990;20(3):255-64.
1990: A J Streeter; Raymond W Nims; P R Sheffels; Y H Heur; Chung S Yang; B A Mico; C T Gombar; Larry K Keefer
Metabolic denitrosation of N-nitrosodimethylamine in vivo in the rat.
Cancer research 1990;50(4):1144-50.
1990: J S Yoo; H S Park; S M Ning; Mao-Jung Lee; Chung S Yang
Effects of thiamine deficiency on hepatic cytochromes P450 and drug-metabolizing enzyme activities.
Biochemical pharmacology 1990;39(3):519-25.
1990: J F Brady; F Xiao; S M Ning; Chung S Yang
Metabolism of methyl tertiary-butyl ether by rat hepatic microsomes.
Archives of toxicology 1990;64(2):157-60.
1990: Chung S Yang; J S Yoo; H Ishizaki; JY Hong
Cytochrome P450IIE1: roles in nitrosamine metabolism and mechanisms of regulation.
Drug metabolism reviews 1990;22(2-3):147-59.
1990: J F Brady; F Xiao; J M Gapac; S M Ning; Chung S Yang
Alteration of rat liver microsomal monooxygenase activities by gasoline treatment.
Archives of toxicology 1990;64(8):677-9.
1989: Q Ma; G A Dannan; F P Guengerich; Chung S Yang
Similarities and differences in the regulation of hepatic cytochrome P-450 enzymes by diabetes and fasting in male rats.
Biochemical pharmacology 1989;38(19):3179-84.
1989: J F Brady; D Li; H Ishizaki; M Lee; S M Ning; F Xiao; Chung S Yang
Induction of cytochromes P450IIE1 and P450IIB1 by secondary ketones and the role of P450IIE1 in chloroform metabolism.
Toxicology and applied pharmacology 1989;100(2):342-9.
1989: JY Hong; J M Pan; S M Ning; Chung S Yang
Molecular basis for the sex-related difference in renal N-nitrosodimethylamine demethylase in C3H/HeJ mice.
Cancer research 1989;49(11):2973-9.
1989: M Lee; H Ishizaki; J F Brady; Chung S Yang
Substrate specificity and alkyl group selectivity in the metabolism of N-nitrosodialkylamines.
Cancer research 1989;49(6):1470-4.
1988: J F Brady; D C Li; H Ishizaki; Chung S Yang
Effect of diallyl sulfide on rat liver microsomal nitrosamine metabolism and other monooxygenase activities.
Cancer research 1988;48(21):5937-40.
1988: Z G Dong; JY Hong; Q A Ma; D C Li; J Bullock; F J Gonzalez; S S Park; H V Gelboin; Chung S Yang
Mechanism of induction of cytochrome P-450ac (P-450j) in chemically induced and spontaneously diabetic rats.
Archives of biochemistry and biophysics 1988;263(1):29-35.
1988: J S Yoo; F P Guengerich; Chung S Yang
Metabolism of N-nitrosodialkylamines by human liver microsomes.
Cancer research 1988;48(6):1499-504.
1988: J F Brady; Mao-Jung Lee; M Li; H Ishizaki; Chung S Yang
Diethyl ether as a substrate for acetone/ethanol-inducible cytochrome P-450 and as an inducer for cytochrome(s) P-450.
Molecular pharmacology 1988;33(2):148-54.
1988: Chung S Yang; J S Yoo
Dietary effects on drug metabolism by the mixed-function oxidase system.
Pharmacology & therapeutics 1988;38(1):53-72.
1987: JY Hong; J M Pan; Z G Dong; S M Ning; Chung S Yang
Regulation of N-nitrosodimethylamine demethylase in rat liver and kidney.
Cancer research 1987;47(22):5948-53.
1987: J S Yoo; R J Cheung; C J Patten; David Wade; Chung S Yang
Nature of N-nitrosodimethylamine demethylase and its inhibitors.
Cancer research 1987;47(13):3378-83.
1987: David Wade; Chung S Yang; C J Metral; J M Roman; Joseph A Hrabie; C W Riggs; T Anjo; Larry K Keefer; B A Mico
Deuterium isotope effect on denitrosation and demethylation of N-nitrosodimethylamine by rat liver microsomes.
Cancer research 1987;47(13):3373-7.
1987: J S Yoo; S M Ning; C J Patten; Chung S Yang
Metabolism and activation of N-nitrosodimethylamine by hamster and rat microsomes: comparative study with weanling and adult animals.
Cancer research 1987;47(4):992-8.
1987: JY Hong; J M Pan; F J Gonzalez; H V Gelboin; Chung S Yang
The induction of a specific form of cytochrome P-450 (P-450j) by fasting.
Biochemical and biophysical research communications 1987;142(3):1077-83.
1987: Larry K Keefer; T Anjo; David Wade; T Wang; Chung S Yang
Concurrent generation of methylamine and nitrite during denitrosation of N-nitrosodimethylamine by rat liver microsomes.
Cancer research 1987;47(2):447-52.
1987: Chung S Yang; David Wade; T Anjo; Larry K Keefer
Kinetic isotope effect on the demethylation and denitrosation of N-nitrosodimethylamine in vitro.
IARC scientific publications 1987;(84):124-8.
1987: Larry K Keefer; T Anjo; Y H Heur; Chung S Yang; B A Mico
Potential for metabolic deactivation of carcinogenic N-nitrosodimethylamine in vivo.
IARC scientific publications 1987;(84):113-6.
1987: Chung S Yang; C Patten; Mao-Jung Lee; M Li; J S Yoo; J Pan; J Hong
Enzymatic mechanisms in the metabolic activation of N-nitrosodialkylamines.
IARC scientific publications 1987;(84):104-8.
1986: C J Patten; S M Ning; A Y Lu; Chung S Yang
Acetone-inducible cytochrome P-450: purification, catalytic activity, and interaction with cytochrome b5.
Archives of biochemistry and biophysics 1986;251(2):629-38.