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Françoise Brignole-Baudouin

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Nicolas Desbenoit; Olivier Laprévote; Isabelle Schmitz-Afonso; David Touboul; Christophe Baudouin; Françoise Brignole-Baudouin; Alain Brunelle
Localisation and quantification of benzalkonium chloride in eye tissue by TOF-SIMS imaging and liquid chromatography mass spectrometry.
Aude Pauly; Christophe Roubeix; Françoise Brignole-Baudouin; Hong Liang; Christophe Baudouin
In vitro and in vivo comparative toxicological study of a new preservative-free latanoprost formulation.
Hong Liang; Christophe Baudouin; Ronald Buggage; Philippe Daull; Jean-Sébastien Garrigue; Françoise Brignole-Baudouin
In vitro and in vivo evaluation of a preservative-free cationic emulsion of latanoprost in corneal wound healing models.

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2013: Nicolas Desbenoit; Olivier Laprévote; Isabelle Schmitz-Afonso; David Touboul; Christophe Baudouin; Françoise Brignole-Baudouin; Alain Brunelle
Localisation and quantification of benzalkonium chloride in eye tissue by TOF-SIMS imaging and liquid chromatography mass spectrometry.
Analytical and bioanalytical chemistry 2013;405(12):4039-49.
2012: Aude Pauly; Christophe Roubeix; Françoise Brignole-Baudouin; Hong Liang; Christophe Baudouin
In vitro and in vivo comparative toxicological study of a new preservative-free latanoprost formulation.
Investigative ophthalmology & visual science 2012;53(13):8172-80.
2012: Hong Liang; Christophe Baudouin; Ronald Buggage; Philippe Daull; Jean-Sébastien Garrigue; Françoise Brignole-Baudouin
In vitro and in vivo evaluation of a preservative-free cationic emulsion of latanoprost in corneal wound healing models.
Cornea 2012;31(11):1319-29.
2012: Alexis Chassignol; Luisa Riancho; Jean-Michel Warnet; Christophe Baudouin; Emmanuelle Brasnu; Françoise Brignole-Baudouin
In vitro interactions between peripheral blood lymphocytes and the Wong-Kilbourne derivative of Chang conjunctival cells.
Investigative ophthalmology & visual science 2012;53(3):1492-8.
2012: Françoise Brignole-Baudouin; Alain Brunelle; Nicolas Desbenoit; Isabelle Fournier; Vincent Guerineau; Gregory Hamm; Olivier Laprevote; Raphael Legouffe; Hong Liang; michel salzet; Jonathan stauber; David Touboul; Maxence Wisztorski; Jean-Pierre Both; Christophe Baudouin
A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits.
PloS one 2012;7(11):e50180.
2012: Hong Liang; Christophe Baudouin; Philippe Daull; Jean-Sébastien Garrigue; Françoise Brignole-Baudouin
Ocular safety of cationic emulsion of cyclosporine in an in vitro corneal wound-healing model and an acute in vivo rabbit model.
Molecular vision 2012;18():2195-204.
2012: Alexandre Denoyer; Julie Frugier; David Godefroy; Jeffrey K Harrison; Serge Picaud; William Rostène; José A Sahel; Francoise Baleux; Françoise Brignole-Baudouin; Isabelle Célérier; Julie Degardin; Christophe Baudouin
CXCR3 antagonism of SDF-1(5-67) restores trabecular function and prevents retinal neurodegeneration in a rat model of ocular hypertension.
PloS one 2012;7(6):e37873.
2012: Chloé Clouzeau; David Godefroy; Luisa Riancho; William Rostène; Christophe Baudouin; Françoise Brignole-Baudouin
Hyperosmolarity potentiates toxic effects of benzalkonium chloride on conjunctival epithelial cells in vitro.
Molecular vision 2012;18():851-63.
2012: Hong Liang; Luisa Riancho; Françoise Brignole-Baudouin; Christophe Baudouin
Reduced in vivo ocular surface toxicity with polyquad-preserved travoprost versus benzalkonium-preserved travoprost or latanoprost ophthalmic solutions.
Ophthalmic research 2012;48(2):89-101.
2012: Hong Liang; Luisa Riancho; Christophe Baudouin; Antoine Labbe; Françoise Brignole-Baudouin
Conjunctiva-associated lymphoid tissue (CALT) reactions to antiglaucoma prostaglandins with or without BAK-preservative in rabbit acute toxicity study.
PloS one 2012;7(3):e33913.
2011: Françoise Brignole-Baudouin; Hong Liang; Luisa Riancho; Christophe Baudouin
Comparative in vitro toxicology study of travoprost polyquad-preserved, travoprost BAK-preserved, and latanoprost BAK-preserved ophthalmic solutions on human conjunctival epithelial cells.
Current eye research 2011;36(11):979-88.
2011: Françoise Brignole-Baudouin; Pasquale Aragona; Stefano Barabino; Christophe Baudouin; Marc Labetoulle; Pierre-Jean Pisella; Maurizio Rolando; Raphaele Siou-Mermet; Catherine Creuzot-Garcher
A multicentre, double-masked, randomized, controlled trial assessing the effect of oral supplementation of omega-3 and omega-6 fatty acids on a conjunctival inflammatory marker in dry eye patients.
Acta ophthalmologica 2011;89(7):e591-7.
2011: Chadi Mehanna; Christophe Baudouin; Françoise Brignole-Baudouin
Spectrofluorometry assays for oxidative stress and apoptosis, with cell viability on the same microplates: a multiparametric analysis and quality control.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(5):1089-96.
2011: Hong Liang; Aude Pauly; Luisa Riancho; Christophe Baudouin; Françoise Brignole-Baudouin
Toxicological evaluation of preservative-containing and preservative-free topical prostaglandin analogues on a three-dimensional-reconstituted corneal epithelium system.
The British journal of ophthalmology 2011;95(6):869-75.
2011: Françoise Brignole-Baudouin; Hong Liang; Zaki Nakib; Luisa Riancho; Christophe Baudouin
In vitro comparative toxicology of polyquad-preserved and benzalkonium chloride-preserved travoprost/timolol fixed combination and latanoprost/timolol fixed combination.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2011;27(3):273-80.
2011: Hong Liang; Françoise Brignole-Baudouin; Aude Pauly; Luisa Riancho; Christophe Baudouin
Polyquad-preserved travoprost/timolol, benzalkonium chloride (BAK)-preserved travoprost/timolol, and latanoprost/timolol in fixed combinations: a rabbit ocular surface study.
Advances in therapy 2011;28(4):311-25.
2010: Christophe Baudouin; Antoine Labbé; Hong Liang; Aude Pauly; Françoise Brignole-Baudouin
Preservatives in eyedrops: the good, the bad and the ugly.
Progress in retinal and eye research 2010;29(4):312-34.
2010: Hannu Uusitalo; Enping Chen; Norbert Pfeiffer; Françoise Brignole-Baudouin; Kai Kaarniranta; Markku Leino; Päivi Puska; Elina Palmgren; Thomas Hamacher; Günter Hofmann; Gernot Petzold; Ulrich Richter; Tobias Riedel; Martin Winter; Auli Ropo
Switching from a preserved to a preservative-free prostaglandin preparation in topical glaucoma medication.
Acta ophthalmologica 2010;88(3):329-36.
2010: Antoine Labbé; Laurent Gheck; Vassiliki Iordanidou; Chadi Mehanna; Françoise Brignole-Baudouin; Christophe Baudouin
An in vivo confocal microscopy and impression cytology evaluation of pterygium activity.
Cornea 2010;29(4):392-9.
2010: Hong Liang; Christophe Baudouin; Benedicte Dupas; Françoise Brignole-Baudouin
Live conjunctiva-associated lymphoid tissue analysis in rabbit under inflammatory stimuli using in vivo confocal microscopy.
Investigative ophthalmology & visual science 2010;51(2):1008-15.
2009: Aude Pauly; Marisa Meloni; Françoise Brignole-Baudouin; Jean-Michel Warnet; Christophe Baudouin
Multiple endpoint analysis of the 3D-reconstituted corneal epithelium after treatment with benzalkonium chloride: early detection of toxic damage.
Investigative ophthalmology & visual science 2009;50(4):1644-52.
2009: Hong Liang; Christophe Baudouin; Marie-Odile Faure; Grégory Lambert; Françoise Brignole-Baudouin
Comparison of the ocular tolerability of a latanoprost cationic emulsion versus conventional formulations of prostaglandins: an in vivo toxicity assay.
Molecular vision 2009;15():1690-9.
2008: Aude Pauly; Antoine Labbe; Christophe Baudouin; Hong Liang; Jean-Michel Warnet; Françoise Brignole-Baudouin
In vivo confocal microscopic grading system for standardized corneal evaluation: application to toxic-induced damage in rat.
Current eye research 2008;33(10):826-38.
2008: Emmanuelle Brasnu; Françoise Brignole-Baudouin; Luisa Riancho; Jean-Marc Guenoun; Jean-Michel Warnet; Christophe Baudouin
In vitro effects of preservative-free tafluprost and preserved latanoprost, travoprost, and bimatoprost in a conjunctival epithelial cell line.
Current eye research 2008;33(4):303-12.
2008: Liem Trinh; Françoise Brignole-Baudouin; Antoine Labbé; Mathilde Raphaël; Jean-Louis Bourges; Christophe Baudouin
The corneal endothelium in an endotoxin-induced uveitis model: correlation between in vivo confocal microscopy and immunohistochemistry.
Molecular vision 2008;14():1149-56.
2008: Mélody Dutot; Hong Liang; Thierry Pauloin; Françoise Brignole-Baudouin; Christophe Baudouin; Jean-Michel Warnet; Patrice Rat
Effects of toxic cellular stresses and divalent cations on the human P2X7 cell death receptor.
Molecular vision 2008;14():889-97.
2008: E Brasnu; Françoise Brignole-Baudouin; L Riancho; Jean-Michel Warnet; Christophe Baudouin
Comparative study on the cytotoxic effects of benzalkonium chloride on the Wong-Kilbourne derivative of Chang conjunctival and IOBA-NHC cell lines.
Molecular vision 2008;14():394-402.
2008: Christophe Baudouin; Hong Liang; Pascale Hamard; Luisa Riancho; Catherine Creuzot-Garcher; Jean-Michel Warnet; Françoise Brignole-Baudouin
The ocular surface of glaucoma patients treated over the long term expresses inflammatory markers related to both T-helper 1 and T-helper 2 pathways.
Ophthalmology 2008;115(1):109-15.
2007: Aude Pauly; Françoise Brignole-Baudouin; Antoine Labbé; Hong Liang; Jean-Michel Warnet; Christophe Baudouin
New tools for the evaluation of toxic ocular surface changes in the rat.
Investigative ophthalmology & visual science 2007;48(12):5473-83.
2007: Liem Trinh; Françoise Brignole-Baudouin; Mathilde Raphaël; Sylvère Dupont-Monod; Nathalie Cassoux; Phuc LeHoang; Christophe Baudouin
Th1 and Th2 responses on the ocular surface in uveitis identified by CCR4 and CCR5 conjunctival expression.
American journal of ophthalmology 2007;144(4):580-5.
2007: Aude Pauly; Françoise Brignole-Baudouin; Jean-Marc Guenoun; Luisa Riancho; Patrice Rat; Jean-Michel Warnet; Christophe Baudouin
Comparative study of topical anti-allergic eye drops on human conjunctiva-derived cells: responses to histamine and IFN gamma and toxicological profiles.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2007;245(4):534-46.
2007: Hong Liang; Françoise Brignole-Baudouin; Antoine Labbé; Aude Pauly; Jean-Michel Warnet; Christophe Baudouin
LPS-stimulated inflammation and apoptosis in corneal injury models.
Molecular vision 2007;13():1169-80.
2007: Antoine Labbé; Françoise Brignole-Baudouin; Christophe Baudouin
[Ocular surface investigations in dry eye].
Journal français d'ophtalmologie 2007;30(1):76-97.
2006: Antoine Labbé; Aude Pauly; Hong Liang; Françoise Brignole-Baudouin; Chantal Martin; Jean-Michel Warnet; Christophe Baudouin
Comparison of toxicological profiles of benzalkonium chloride and polyquaternium-1: an experimental study.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2006;22(4):267-78.
2006: Mélody Dutot; François Pouzaud; Isabelle Larosche; Françoise Brignole-Baudouin; Jean-Michel Warnet; Patrice Rat
Fluoroquinolone eye drop-induced cytotoxicity: role of preservative in P2X7 cell death receptor activation and apoptosis.
Investigative ophthalmology & visual science 2006;47(7):2812-9.
2006: Antoine Labbé; Hong Liang; Chantal Martin; Françoise Brignole-Baudouin; Jean-Michel Warnet; Christophe Baudouin
Comparative anatomy of laboratory animal corneas with a new-generation high-resolution in vivo confocal microscope.
Current eye research 2006;31(6):501-9.
2006: H Liang; Christophe Baudouin; Pascale Hamard; Catherine Creuzot-Garcher; Jean-Michel Warnet; Françoise Brignole-Baudouin
[Activation of TH1/TH2 pathways detected through the expression of CCR4 and CCR5 on the ocular surface of glaucomatous patients treated over the long term].
Journal français d'ophtalmologie 2006;29(2):121-6.
2006: Hong Liang; Christophe Baudouin; Antoine Labbé; Aude Pauly; Chantal Martin; Jean-Michel Warnet; Françoise Brignole-Baudouin
In vivo confocal microscopy and ex vivo flow cytometry: new tools for assessing ocular inflammation applied to rabbit lipopolysaccharide-induced conjunctivitis.
Molecular vision 2006;12():1392-402.
2005: Jean-Marc Guenoun; Christophe Baudouin; Patrice Rat; Aude Pauly; Jean-Michel Warnet; Françoise Brignole-Baudouin
In vitro comparison of cytoprotective and antioxidative effects of latanoprost, travoprost, and bimatoprost on conjunctiva-derived epithelial cells.
Investigative ophthalmology & visual science 2005;46(12):4594-9.
2005: Christophe Baudouin; Hong Liang; Dominique Bremond-Gignac; Pascale Hamard; Raymond Hreiche; Catherine Creuzot-Garcher; Jean-Michel Warnet; Françoise Brignole-Baudouin
CCR 4 and CCR 5 expression in conjunctival specimens as differential markers of T(H)1/ T(H)2 in ocular surface disorders.
The Journal of allergy and clinical immunology 2005;116(3):614-9.
2005: Jean-Marc Guenoun; Christophe Baudouin; Patrice Rat; Aude Pauly; Jean-Michel Warnet; Françoise Brignole-Baudouin
In vitro study of inflammatory potential and toxicity profile of latanoprost, travoprost, and bimatoprost in conjunctiva-derived epithelial cells.
Investigative ophthalmology & visual science 2005;46(7):2444-50.
2004: Françoise Brignole-Baudouin; Ann-Christin Ott; Jean-Michel Warnet; Christophe Baudouin
Flow cytometry in conjunctival impression cytology: a new tool for exploring ocular surface pathologies.
Experimental eye research 2004;78(3):473-81.
2003: Larry Bensoussan; Catherine Blondin; Christophe Baudouin; Pascale Hamard; G Sabeh Afaki; Catherine Creuzot-Garcher; Jean-Michel Warnet; Françoise Brignole-Baudouin
[Flow cytometric analysis of HLA-DR, IL-6 and IL-8 expression by conjunctival epithelial cells from patients with prolonged topical antiglaucoma treatments].
Journal français d'ophtalmologie 2003;26(8):782-9.
2002: Jean Feuillard; Marie-Christine Jacob; Françoise Valensi; Marc Maynadié; Rémy Gressin; Laurence Chaperot; Christine Arnoulet; Françoise Brignole-Baudouin; Bernard Drénou; Eliane Duchayne; Annie Falkenrodt; Richard Garand; Emanuelle Homolle; Bernard Husson; Emilienne Kuhlein; Geneviève Le Calvez; Danielle Sainty; Marie-France Sotto; Franck Trimoreau; marie bene
Clinical and biologic features of CD4(+)CD56(+) malignancies.
Blood 2002;99(5):1556-63.