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Donglai Yang

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Chemicals & Drugs

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TOP 3
Allison B Edsall; Arasambattu K Mohanakrishnan; Donglai Yang; Phillip E Fanwick; Ernest Hamel; Arthur D Hanson; Gregory E Agoston; Mark Cushman
Effects of altering the electronics of 2-methoxyestradiol on cell proliferation, on cytotoxicity in human cancer cell cultures, and on tubulin polymerization.
Mark Cushman; Donglai Yang; Jeffrey T Mihalic; Jinhua Chen; Stefan Gerhardt; Robert Huber; Markus Fischer; Klaus Kis; Adelbert Bacher
Incorporation of an amide into 5-phosphonoalkyl-6-D-ribitylaminopyrimidinedione lumazine synthase inhibitors results in an unexpected reversal of selectivity for riboflavin synthase vs lumazine synthase.
Mark Cushman; Donglai Yang; Stefan Gerhardt; Robert Huber; Markus Fischer; Klaus Kis; Adelbert Bacher
Design, synthesis, and evaluation of 6-carboxyalkyl and 6-phosphonoxyalkyl derivatives of 7-oxo-8-ribitylaminolumazines as inhibitors of riboflavin synthase and lumazine synthase.

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2004: Allison B Edsall; Arasambattu K Mohanakrishnan; Donglai Yang; Phillip E Fanwick; Ernest Hamel; Arthur D Hanson; Gregory E Agoston; Mark Cushman
Effects of altering the electronics of 2-methoxyestradiol on cell proliferation, on cytotoxicity in human cancer cell cultures, and on tubulin polymerization.
Journal of medicinal chemistry 2004;47(21):5126-39.
2002: Mark Cushman; Donglai Yang; Jeffrey T Mihalic; Jinhua Chen; Stefan Gerhardt; Robert Huber; Markus Fischer; Klaus Kis; Adelbert Bacher
Incorporation of an amide into 5-phosphonoalkyl-6-D-ribitylaminopyrimidinedione lumazine synthase inhibitors results in an unexpected reversal of selectivity for riboflavin synthase vs lumazine synthase.
The Journal of organic chemistry 2002;67(20):6871-7.
2002: Mark Cushman; Donglai Yang; Stefan Gerhardt; Robert Huber; Markus Fischer; Klaus Kis; Adelbert Bacher
Design, synthesis, and evaluation of 6-carboxyalkyl and 6-phosphonoxyalkyl derivatives of 7-oxo-8-ribitylaminolumazines as inhibitors of riboflavin synthase and lumazine synthase.
The Journal of organic chemistry 2002;67(16):5807-16.
2001: Mark Cushman; Donglai Yang; Klaus Kis; Adelbert Bacher
Design, synthesis, and evaluation of 9-D-ribityl-1,3,7-trihydro-2,6,8-purinetrione, a potent inhibitor of riboflavin synthase and lumazine synthase.
The Journal of organic chemistry 2001;66(25):8320-7.
2000: Z Wang; Donglai Yang; Arasambattu K Mohanakrishnan; Phillip E Fanwick; P Nampoothiri; Ernest Hamel; Mark Cushman
Synthesis of B-ring homologated estradiol analogues that modulate tubulin polymerization and microtubule stability.
Journal of medicinal chemistry 2000;43(12):2419-29.