David Briles

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Schachern Patricia A; Tsuprun Vladimir; Cureoglu Sebahattin; Ferrieri Patricia; Briles David E; Paparella Michael M; Juhn Steven
Virulence of pneumococcal proteins on the inner ear.
Tsuprun Vladimir; Cureoglu Sebahattin; Schachern Patricia A; Ferrieri Patricia; Briles David E; Paparella Michael M; Juhn Steven K
Role of pneumococcal proteins in sensorineural hearing loss due to otitis media.
Melin Merit M; Hollingshead Susan K; Briles David E; Lahdenkari Mika I; Kilpi Terhi M; Käyhty Helena M
Development of antibodies to PspA families 1 and 2 in children after exposure to Streptococcus pneumoniae.

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All Publications

2009: Schachern Patricia A; Tsuprun Vladimir; Cureoglu Sebahattin; Ferrieri Patricia; Briles David E; Paparella Michael M; Juhn Steven
Virulence of pneumococcal proteins on the inner ear.
Archives of otolaryngology--head & neck surgery 2009;135(7):657-61.
2008: Tsuprun Vladimir; Cureoglu Sebahattin; Schachern Patricia A; Ferrieri Patricia; Briles David E; Paparella Michael M; Juhn Steven K
Role of pneumococcal proteins in sensorineural hearing loss due to otitis media.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2008;29(8):1056-60.
2008: Melin Merit M; Hollingshead Susan K; Briles David E; Lahdenkari Mika I; Kilpi Terhi M; Käyhty Helena M
Development of antibodies to PspA families 1 and 2 in children after exposure to Streptococcus pneumoniae.
Clinical and vaccine immunology : CVI 2008;15(10):1529-35.
2008: Melin Merit M; Hollingshead Susan K; Briles David E; Hanage William P; Lahdenkari Mika; Kaijalainen Tarja; Kilpi Terhi M; Käyhty Helena M
Distribution of pneumococcal surface protein A families 1 and 2 among Streptococcus pneumoniae isolates from children in finland who had acute otitis media or were nasopharyngeal carriers.
Clinical and vaccine immunology : CVI 2008;15(10):1555-63.
2008: Torii Ikuko; Oka Satoshi; Hotomi Muneki; Benjamin William H; Takai Toshiyuki; Kearney John F; Briles David E; Kubagawa Hiromi
PIR-B-deficient mice are susceptible to Salmonella infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):4229-39.
2008: Denzel Andrea; Maus Ulrich A; Rodriguez Gomez Manuel; Moll Cordula; Niedermeier Marianne; Winter Christine; Maus Regina; Hollingshead Susan; Briles David E; Kunz-Schughart Leoni A; Talke Yvonne; Mack Matthias
Basophils enhance immunological memory responses.
Nature immunology 2008;9(7):733-42.
2008: Glover David T; Hollingshead Susan K; Briles David E
Streptococcus pneumoniae surface protein PcpA elicits protection against lung infection and fatal sepsis.
Infection and immunity 2008;76(6):2767-76.
2008: Hembre Berit S H; Briles David E; Grewal Harleen M S; Strand Tor A
Effect of high dose oral zinc in mice with severe infection with Streptococcus pneumoniae.
Scandinavian journal of infectious diseases 2008;40(5):363-7.
2007: Li Jie; Glover David T; Szalai Alexander J; Hollingshead Susan K; Briles David E
PspA and PspC minimize immune adherence and transfer of pneumococci from erythrocytes to macrophages through their effects on complement activation.
Infection and immunity 2007;75(12):5877-85.
2007: Basset Alan; Thompson Claudette M; Hollingshead Susan K; Briles David E; Ades Edwin W; Lipsitch Marc; Malley Richard
Antibody-independent, CD4+ T-cell-dependent protection against pneumococcal colonization elicited by intranasal immunization with purified pneumococcal proteins.
Infection and immunity 2007;75(11):5460-4.
2007: Senkovich Olga; Cook William J; Mirza Shaper; Hollingshead Susan K; Protasevich Irina I; Briles David E; Chattopadhyay Debasish
Structure of a complex of human lactoferrin N-lobe with pneumococcal surface protein a provides insight into microbial defense mechanism.
Journal of molecular biology 2007;370(4):701-13.
2006: Baril L; Dietemann J; Essevaz-Roulet M; Béniguel L; Coan P; Briles D E; Guy B; Cozon G
Pneumococcal surface protein A (PspA) is effective at eliciting T cell-mediated responses during invasive pneumococcal disease in adults.
Clinical and experimental immunology 2006;145(2):277-86.
2006: Daniels Calvin C; Briles Travis C; Mirza Shaper; Håkansson Anders P; Briles David E
Capsule does not block antibody binding to PspA, a surface virulence protein of Streptococcus pneumoniae.
Microbial pathogenesis 2006;40(5):228-33.
2006: Palaniappan Ravichandran; Singh Shailesh; Singh Udai P; Singh Rajesh; Ades Edwin W; Briles David E; Hollingshead Susan K; Royal Walter; Sampson Jacquelyn S; Stiles Jonathan K; Taub Dennis D; Lillard James W
CCL5 modulates pneumococcal immunity and carriage.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(4):2346-56.
2006: Hollingshead Susan K; Baril Laurence; Ferro Santiago; King Janice; Coan Pat; Briles David E;
Pneumococcal surface protein A (PspA) family distribution among clinical isolates from adults over 50 years of age collected in seven countries.
Journal of medical microbiology 2006;55(Pt 2):215-21.
2006: Johnston Jason W; Briles David E; Myers Lisa E; Hollingshead Susan K
Mn2+-dependent regulation of multiple genes in Streptococcus pneumoniae through PsaR and the resultant impact on virulence.
Infection and immunity 2006;74(2):1171-80.
2005: Briles David E; Novak Lea; Hotomi Muneki; van Ginkel Frederik W; King Janice
Nasal colonization with Streptococcus pneumoniae includes subpopulations of surface and invasive pneumococci.
Infection and immunity 2005;73(10):6945-51.
2005: Coats Mamie T; Benjamin W H; Hollingshead S K; Briles D E
Antibodies to the pneumococcal surface protein A, PspA, can be produced in splenectomized and can protect splenectomized mice from infection with Streptococcus pneumoniae.
Vaccine 2005;23(33):4257-62.
2005: Johnson Crystal N; Briles David E; Benjamin William H; Hollingshead Susan K; Waites Ken B
Relative fitness of fluoroquinolone-resistant Streptococcus pneumoniae.
Emerging infectious diseases 2005;11(6):814-20.
2005: Palaniappan Ravichandran; Singh Shailesh; Singh Udai P; Sakthivel Senthil Kumar K; Ades Edwin W; Briles David E; Hollingshead Susan K; Paton James C; Sampson Jacquelyn S; Lillard James W
Differential PsaA-, PspA-, PspC-, and PdB-specific immune responses in a mouse model of pneumococcal carriage.
Infection and immunity 2005;73(2):1006-13.
2004: Ren Bing; McCrory Mark A; Pass Christina; Bullard Daniel C; Ballantyne Christie M; Xu Yuanyuan; Briles David E; Szalai Alexander J
The virulence function of Streptococcus pneumoniae surface protein A involves inhibition of complement activation and impairment of complement receptor-mediated protection.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(12):7506-12.
2004: Baril Laurence; Briles David E; Crozier Pierre; King Janice; Punar Metin; Hollingshead Susan K; McCormick Joseph B
Characterization of antibodies to PspA and PsaA in adults over 50 years of age with invasive pneumococcal disease.
Vaccine 2004;23(6):789-93.
2004: Johnston Jason W; Myers Lisa E; Ochs Martina M; Benjamin William H; Briles David E; Hollingshead Susan K
Lipoprotein PsaA in virulence of Streptococcus pneumoniae: surface accessibility and role in protection from superoxide.
Infection and immunity 2004;72(10):5858-67.
2004: Shaper Mirza; Hollingshead Susan K; Benjamin William H; Briles David E
PspA protects Streptococcus pneumoniae from killing by apolactoferrin, and antibody to PspA enhances killing of pneumococci by apolactoferrin [corrected].
Infection and immunity 2004;72(9):5031-40.
2004: Baril L; Briles D E; Crozier P; King J D; Hollingshead S K; Murphy T F; McCormick J B
Natural materno-fetal transfer of antibodies to PspA and to PsaA.
Clinical and experimental immunology 2004;135(3):474-7.
2004: Briles David E
Protection of the elderly from pneumococcal pneumonia with a protein-based vaccine?
Mechanisms of ageing and development 2004;125(2):129-31.
2004: Ren Bing; Szalai Alexander J; Hollingshead Susan K; Briles David E
Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface.
Infection and immunity 2004;72(1):114-22.
2003: Swiatlo E; King J; Nabors G S; Mathews B; Briles D E
Pneumococcal surface protein A is expressed in vivo, and antibodies to PspA are effective for therapy in a murine model of pneumococcal sepsis.
Infection and immunity 2003;71(12):7149-53.
2003: van Ginkel Frederik W; McGhee Jerry R; Watt James M; Campos-Torres Antonio; Parish Lindsay A; Briles David E
Pneumococcal carriage results in ganglioside-mediated olfactory tissue infection.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):14363-7.
2003: Roche Hazeline; Ren Bing; McDaniel Larry S; Håkansson Anders; Briles David E
Relative roles of genetic background and variation in PspA in the ability of antibodies to PspA to protect against capsular type 3 and 4 strains of Streptococcus pneumoniae.
Infection and immunity 2003;71(8):4498-505.
2003: Briles David E; Hollingshead Susan K; Paton James C; Ades Edwin W; Novak Lea; van Ginkel Frederik W; Benjamin William H
Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae.
The Journal of infectious diseases 2003;188(3):339-48.
2003: Yu Jigui; Briles David E; Englund Janet A; Hollingshead Susan K; Glezen W Paul; Nahm Moon H
Immunogenic protein contaminants in pneumococcal vaccines.
The Journal of infectious diseases 2003;187(6):1019-23.
2003: Roche Hazeline; Håkansson Anders; Hollingshead Susan K; Briles David E
Regions of PspA/EF3296 best able to elicit protection against Streptococcus pneumoniae in a murine infection model.
Infection and immunity 2003;71(3):1033-41.
2003: Ren Bing; Szalai Alexander J; Thomas Orlanda; Hollingshead Susan K; Briles David E
Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae.
Infection and immunity 2003;71(1):75-85.
2002: Robinson D Ashley; Briles David E; Crain Marilyn J; Hollingshead Susan K
Evolution and virulence of serogroup 6 pneumococci on a global scale.
Journal of bacteriology 2002;184(22):6367-75.
2002: Balachandran Priya; Brooks-Walter Alexis; Virolainen-Julkunen Anni; Hollingshead Susan K; Briles David E
Role of pneumococcal surface protein C in nasopharyngeal carriage and pneumonia and its ability to elicit protection against carriage of Streptococcus pneumoniae.
Infection and immunity 2002;70(5):2526-34.
2002: Smith Alexander W; Roche Hazeline; Trombe Marie-Claude; Briles David E; Håkansson Anders
Characterization of the dihydrolipoamide dehydrogenase from Streptococcus pneumoniae and its role in pneumococcal infection.
Molecular microbiology 2002;44(2):431-48.
2001: Malley R; Lipsitch M; Stack A; Saladino R; Fleisher G; Pelton S; Thompson C; Briles D; Anderson P
Intranasal immunization with killed unencapsulated whole cells prevents colonization and invasive disease by capsulated pneumococci.
Infection and immunity 2001;69(8):4870-3.
2001: Balachandran P; Hollingshead S K; Paton J C; Briles D E
The autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysin.
Journal of bacteriology 2001;183(10):3108-16.
2001: Robinson D A; Edwards K M; Waites K B; Briles D E; Crain M J; Hollingshead S K
Clones of Streptococcus pneumoniae isolated from nasopharyngeal carriage and invasive disease in young children in central Tennessee.
The Journal of infectious diseases 2001;183(10):1501-7.
2001: Håkansson A; Roche H; Mirza S; McDaniel L S; Brooks-Walter A; Briles D E
Characterization of binding of human lactoferrin to pneumococcal surface protein A.
Infection and immunity 2001;69(5):3372-81.
2001: Hollingshead S K; Briles D E
Streptococcus pneumoniae: new tools for an old pathogen.
Current opinion in microbiology 2001;4(1):71-7.
2000: Briles D E; Hollingshead S K; Nabors G S; Paton J C; Brooks-Walter A
The potential for using protein vaccines to protect against otitis media caused by Streptococcus pneumoniae.
Vaccine 2000;19 Suppl 1():S87-95.
2000: Briles D E; Hollingshead S K; King J; Swift A; Braun P A; Park M K; Ferguson L M; Nahm M H; Nabors G S
Immunization of humans with recombinant pneumococcal surface protein A (rPspA) elicits antibodies that passively protect mice from fatal infection with Streptococcus pneumoniae bearing heterologous PspA.
The Journal of infectious diseases 2000;182(6):1694-701.
2000: Hollingshead S K; Becker R; Briles D E
Diversity of PspA: mosaic genes and evidence for past recombination in Streptococcus pneumoniae.
Infection and immunity 2000;68(10):5889-900.
2000: Rapola S; Jäntti V; Haikala R; Syrjänen R; Carlone G M; Sampson J S; Briles D E; Paton J C; Takala A K; Kilpi T M; Käyhty H
Natural development of antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A, and pneumolysin in relation to pneumococcal carriage and acute otitis media.
The Journal of infectious diseases 2000;182(4):1146-52.
2000: Lipsitch M; Dykes J K; Johnson S E; Ades E W; King J; Briles D E; Carlone G M
Competition among Streptococcus pneumoniae for intranasal colonization in a mouse model.
Vaccine 2000;18(25):2895-901.
2000: De B K; Sampson J S; Ades E W; Huebner R C; Jue D L; Johnson S E; Espina M; Stinson A R; Briles D E; Carlone G M
Purification and characterization of Streptococcus pneumoniae palmitoylated pneumococcal surface adhesin A expressed in Escherichia coli.
Vaccine 2000;18(17):1811-21.
2000: Nabors G S; Braun P A; Herrmann D J; Heise M L; Pyle D J; Gravenstein S; Schilling M; Ferguson L M; Hollingshead S K; Briles D E; Becker R S
Immunization of healthy adults with a single recombinant pneumococcal surface protein A (PspA) variant stimulates broadly cross-reactive antibodies to heterologous PspA molecules.
Vaccine 2000;18(17):1743-54.
2000: Virolainen A; Russell W; Crain M J; Rapola S; Käyhty H; Briles D E
Human antibodies to pneumococcal surface protein A in health and disease.
The Pediatric infectious disease journal 2000;19(2):134-8.
2000: Briles D E; Hollingshead S; Brooks-Walter A; Nabors G S; Ferguson L; Schilling M; Gravenstein S; Braun P; King J; Swift A
The potential to use PspA and other pneumococcal proteins to elicit protection against pneumococcal infection.
Vaccine 2000;18(16):1707-11.
2000: Briles D E; Ades E; Paton J C; Sampson J S; Carlone G M; Huebner R C; Virolainen A; Swiatlo E; Hollingshead S K
Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae.
Infection and immunity 2000;68(2):796-800.
2000: Hwang Y i; Nahm M H; Briles D E; Thomas D; Purkerson J M
Acquired, but not innate, immune responses to Streptococcus pneumoniae are compromised by neutralization of CD40L.
Infection and immunity 2000;68(2):511-7.
1999: Brooks-Walter A; Briles D E; Hollingshead S K
The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia.
Infection and immunity 1999;67(12):6533-42.
1999: Tu A H; Fulgham R L; McCrory M A; Briles D E; Szalai A J
Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae.
Infection and immunity 1999;67(9):4720-4.
1999: O'Brien D P; Briles D E; Szalai A J; Tu A H; Sanz I; Nahm M H
Tumor necrosis factor alpha receptor I is important for survival from Streptococcus pneumoniae infections.
Infection and immunity 1999;67(2):595-601.
1999: Robinson D A; Turner J S; Facklam R R; Parkinson A J; Breiman R F; Gratten M; Steinhoff M C; Hollingshead S K; Briles D E; Crain M J
Molecular characterization of a globally distributed lineage of serotype 12F Streptococcus pneumoniae causing invasive disease.
The Journal of infectious diseases 1999;179(2):414-22.
1999: Prellner K; Hermansson A; White P; Melhus A; Briles D
Immunization and protection in pneumococcal otitis media studied in a rat model.
Microbial drug resistance (Larchmont, N.Y.) 1999;5(1):73-82.
1998: Briles D E; Tart R C; Swiatlo E; Dillard J P; Smith P; Benton K A; Ralph B A; Brooks-Walter A; Crain M J; Hollingshead S K; McDaniel L S
Pneumococcal diversity: considerations for new vaccine strategies with emphasis on pneumococcal surface protein A (PspA).
Clinical microbiology reviews 1998;11(4):645-57.
1998: Robinson D A; Hollingshead S K; Musser J M; Parkinson A J; Briles D E; Crain M J
The IS1167 insertion sequence is a phylogenetically informative marker among isolates of serotype 6B Streptococcus pneumoniae.
Journal of molecular evolution 1998;47(2):222-9.
1998: Benton K A; VanCott J L; Briles D E
Role of tumor necrosis factor alpha in the host response of mice to bacteremia caused by pneumolysin-deficient Streptococcus pneumoniae.
Infection and immunity 1998;66(2):839-42.
1997: Saladino R A; Stack A M; Fleisher G R; Thompson C M; Briles D E; Kobzik L; Siber G R
Development of a model of low-inoculum Streptococcus pneumoniae intrapulmonary infection in infant rats.
Infection and immunity 1997;65(11):4701-4.
1997: Benton K A; Paton J C; Briles D E
The hemolytic and complement-activating properties of pneumolysin do not contribute individually to virulence in a pneumococcal bacteremia model.
Microbial pathogenesis 1997;23(4):201-9.
1997: Wu H Y; Virolainen A; Mathews B; King J; Russell M W; Briles D E
Establishment of a Streptococcus pneumoniae nasopharyngeal colonization model in adult mice.
Microbial pathogenesis 1997;23(3):127-37.
1997: Swiatlo E; Brooks-Walter A; Briles D E; McDaniel L S
Oligonucleotides identify conserved and variable regions of pspA and pspA-like sequences of Streptococcus pneumoniae.
Gene 1997;188(2):279-84.
1997: Benton K A; Paton J C; Briles D E
Differences in virulence for mice among Streptococcus pneumoniae strains of capsular types 2, 3, 4, 5, and 6 are not attributable to differences in pneumolysin production.
Infection and immunity 1997;65(4):1237-44.
1997: Wu H Y; Nahm M H; Guo Y; Russell M W; Briles D E
Intranasal immunization of mice with PspA (pneumococcal surface protein A) can prevent intranasal carriage, pulmonary infection, and sepsis with Streptococcus pneumoniae.
The Journal of infectious diseases 1997;175(4):839-46.
1997: Yamamoto M; McDaniel L S; Kawabata K; Briles D E; Jackson R J; McGhee J R; Kiyono H
Oral immunization with PspA elicits protective humoral immunity against Streptococcus pneumoniae infection.
Infection and immunity 1997;65(2):640-4.
1997: Briles D E; Hollingshead S K; Swiatlo E; Brooks-Walter A; Szalai A; Virolainen A; McDaniel L S; Benton K A; White P; Prellner K; Hermansson A; Aerts P C; Van Dijk H; Crain M J
PspA and PspC: their potential for use as pneumococcal vaccines.
Microbial drug resistance (Larchmont, N.Y.) 1997;3(4):401-8.
1996: Cartner S C; Simecka J W; Briles D E; Cassell G H; Lindsey J R
Resistance to mycoplasmal lung disease in mice is a complex genetic trait.
Infection and immunity 1996;64(12):5326-31.
1996: Szalai A J; Briles D E; Volanakis J E
Role of complement in C-reactive-protein-mediated protection of mice from Streptococcus pneumoniae.
Infection and immunity 1996;64(11):4850-3.
1996: Briles D E; Tart R C; Wu H Y; Ralph B A; Russell M W; McDaniel L S
Systemic and mucosal protective immunity to pneumococcal surface protein A.
Annals of the New York Academy of Sciences 1996;797():118-26.
1996: Crain M J; Turner J S; Robinson D A; Coffey T J; Brooks-Walter A; McDaniel L S; Briles D E
Evidence for the simultaneous expression of two PspAs by a clone of capsular serotype 6B Streptococcus pneumoniae.
Microbial pathogenesis 1996;21(4):265-75.
1996: Swiatlo E; Crain M J; McDaniel L S; Brooks-Walter A; Coffey T J; Spratt B G; Morrison D A; Briles D E
DNA polymorphisms and variant penicillin-binding proteins as evidence that relatively penicillin-resistant pneumococci in western Canada are clonally related.
The Journal of infectious diseases 1996;174(4):884-8.
1996: Briles D E; King J D; Gray M A; McDaniel L S; Swiatlo E; Benton K A
PspA, a protection-eliciting pneumococcal protein: immunogenicity of isolated native PspA in mice.
Vaccine 1996;14(9):858-67.
1996: Swiatlo E; Benton K; Briles D E
Pneumococcal vaccine response in human immunodeficiency virus-infected patients.
The Journal of infectious diseases 1996;173(3):777-8.
1996: Tart R C; McDaniel L S; Ralph B A; Briles D E
Truncated Streptococcus pneumoniae PspA molecules elicit cross-protective immunity against pneumococcal challenge in mice.
The Journal of infectious diseases 1996;173(2):380-6.
1995: Szalai A J; Briles D E; Volanakis J E
Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(5):2557-63.
1995: Benton K A; Everson M P; Briles D E
A pneumolysin-negative mutant of Streptococcus pneumoniae causes chronic bacteremia rather than acute sepsis in mice.
Infection and immunity 1995;63(2):448-55.
1994: McDaniel L S; Ralph B A; McDaniel D O; Briles D E
Localization of protection-eliciting epitopes on PspA of Streptococcus pneumoniae between amino acid residues 192 and 260.
Microbial pathogenesis 1994;17(5):323-37.
1994: Ralph B A; Briles D E; McDaniel L S
Cross-reactive protection eliciting epitopes of pneumococcal surface protein A.
Annals of the New York Academy of Sciences 1994;730():361-3.
1994: Dunlap N E; Benjamin W H; Briles D E
The intracellular nature of Salmonella infection during the early stages of mouse typhoid.
Immunology series 1994;60():303-12.
1993: Dunlap N E; Briles D E
Immunology of tuberculosis.
The Medical clinics of North America 1993;77(6):1235-51.
1993: Dunlap N E; Ballinger S; Reed T; Christian J C; Koopman W J; Briles D E
The use of monozygotic and dizygotic twins to estimate the effects of inheritance on the levels of immunoglobulin isotypes and antibodies to phosphocholine.
Clinical immunology and immunopathology 1993;66(2):176-80.
1992: Talkington D F; Voellinger D C; McDaniel L S; Briles D E
Analysis of pneumococcal PspA microheterogeneity in SDS polyacrylamide gels and the association of PspA with the cell membrane.
Microbial pathogenesis 1992;13(5):343-55.
1992: McDaniel L S; Sheffield J S; Swiatlo E; Yother J; Crain M J; Briles D E
Molecular localization of variable and conserved regions of pspA and identification of additional pspA homologous sequences in Streptococcus pneumoniae.
Microbial pathogenesis 1992;13(4):261-9.
1992: Dunlap N E; Benjamin W H; Berry A K; Eldridge J H; Briles D E
A 'safe-site' for Salmonella typhimurium is within splenic polymorphonuclear cells.
Microbial pathogenesis 1992;13(3):181-90.
1992: Munoz R; Musser J M; Crain M; Briles D E; Marton A; Parkinson A J; Sorensen U; Tomasz A
Geographic distribution of penicillin-resistant clones of Streptococcus pneumoniae: characterization by penicillin-binding protein profile, surface protein A typing, and multilocus enzyme analysis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1992;15(1):112-8.
1992: Briles D E; Forman C; Crain M
Mouse antibody to phosphocholine can protect mice from infection with mouse-virulent human isolates of Streptococcus pneumoniae.
Infection and immunity 1992;60(5):1957-62.
1992: Waltman W D; Talkington D F; Lipinski A E; Crain M J; Dixon J M; Briles D E
Evidence for a clonal origin of relative penicillin resistance among type 9L pneumococci in northwestern Canada.
The Journal of infectious diseases 1992;165(4):671-5.
1992: Yother J; Handsome G L; Briles D E
Truncated forms of PspA that are secreted from Streptococcus pneumoniae and their use in functional studies and cloning of the pspA gene.
Journal of bacteriology 1992;174(2):610-8.
1992: Yother J; Briles D E
Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis.
Journal of bacteriology 1992;174(2):601-9.
1992: Briles D E; Crain M J; Gray B M; Forman C; Yother J
Strong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae.
Infection and immunity 1992;60(1):111-6.
1991: Benjamin W H; Yother J; Hall P; Briles D E
The Salmonella typhimurium locus mviA regulates virulence in Itys but not Ityr mice: functional mviA results in avirulence; mutant (nonfunctional) mviA results in virulence.
The Journal of experimental medicine 1991;174(5):1073-83.
1991: Benjamin W H; Hall P; Briles D E
A hemA mutation renders Salmonella typhimurium avirulent in mice, yet capable of eliciting protection against intravenous infection with S. typhimurium.
Microbial pathogenesis 1991;11(4):289-95.
1991: Waltman W D; Gray B M; Svanborg C; Facklam R; Briles D E
Epidemiologic studies of group 9 pneumococci in terms of protein type and 9N versus 9V capsular type.
The Journal of infectious diseases 1991;163(4):812-8.
1991: Talkington D F; Crimmins D L; Voellinger D C; Yother J; Briles D E
A 43-kilodalton pneumococcal surface protein, PspA: isolation, protective abilities, and structural analysis of the amino-terminal sequence.
Infection and immunity 1991;59(4):1285-9.
1991: Dunlap N E; Benjamin W H; McCall R D; Tilden A B; Briles D E
A 'safe-site' for Salmonella typhimurium is within splenic cells during the early phase of infection in mice.
Microbial pathogenesis 1991;10(4):297-310.
1991: McDaniel L S; Sheffield J S; Delucchi P; Briles D E
PspA, a surface protein of Streptococcus pneumoniae, is capable of eliciting protection against pneumococci of more than one capsular type.
Infection and immunity 1991;59(1):222-8.
1991: Vakil M; Briles D E; Kearney J F
Antigen-independent selection of T15 idiotype during B-cell ontogeny in mice.
Developmental immunology 1991;1(3):203-12.
1990: Crain M J; Waltman W D; Turner J S; Yother J; Talkington D F; McDaniel L S; Gray B M; Briles D E
Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae.
Infection and immunity 1990;58(10):3293-9.
1990: Benjamin W H; Hall P; Roberts S J; Briles D E
The primary effect of the Ity locus is on the rate of growth of Salmonella typhimurium that are relatively protected from killing.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(8):3143-51.
1990: Waltman W D; McDaniel L S; Gray B M; Briles D E
Variation in the molecular weight of PspA (pneumococcal surface protein A) among Streptococcus pneumoniae.
Microbial pathogenesis 1990;8(1):61-9.
1989: Briles D E; Forman C; Horowitz J C; Volanakis J E; Benjamin W H; McDaniel L S; Eldridge J; Brooks J
Antipneumococcal effects of C-reactive protein and monoclonal antibodies to pneumococcal cell wall and capsular antigens.
Infection and immunity 1989;57(5):1457-64.
1988: McDaniel L S; Briles D E
A pneumococcal surface protein (PspB) that exhibits the same protease sensitivity as streptococcal R antigen.
Infection and immunity 1988;56(11):3001-3.
1988: Waltman W D; McDaniel L S; Andersson B; Bland L; Gray B M; Eden C S; Briles D E
Protein serotyping of Streptococcus pneumoniae based on reactivity to six monoclonal antibodies.
Microbial pathogenesis 1988;5(3):159-67.
1988: Waltman W D; Gray B; McDaniel L S; Briles D E
Cross-reactive monoclonal antibodies for diagnosis of pneumococcal meningitis.
Journal of clinical microbiology 1988;26(9):1635-40.
1988: Briles D E; Yother J; McDaniel L S
Role of pneumococcal surface protein A in the virulence of Streptococcus pneumoniae.
Reviews of infectious diseases 1988;10 Suppl 2():S372-4.
1987: McDaniel L S; Waltman W D; Gray B; Briles D E
A protective monoclonal antibody that reacts with a novel antigen of pneumococcal teichoic acid.
Microbial pathogenesis 1987;3(4):249-60.
1987: McDaniel L S; Yother J; Vijayakumar M; McGarry L; Guild W R; Briles D E
Use of insertional inactivation to facilitate studies of biological properties of pneumococcal surface protein A (PspA).
The Journal of experimental medicine 1987;165(2):381-94.
1986: Yother J; McDaniel L S; Briles D E
Transformation of encapsulated Streptococcus pneumoniae.
Journal of bacteriology 1986;168(3):1463-5.
1986: McDaniel L S; Scott G; Widenhofer K; Carroll J M; Briles D E
Analysis of a surface protein of Streptococcus pneumoniae recognised by protective monoclonal antibodies.
Microbial pathogenesis 1986;1(6):519-31.
1986: Benjamin W H; Posey B S; Briles D E
Effects of in vitro growth phase on the pathogenesis of Salmonella typhimurium in mice.
Journal of general microbiology 1986;132(5):1283-95.
1986: Benjamin W H; Turnbough C L; Goguen J D; Posey B S; Briles D E
Genetic mapping of novel virulence determinants of Salmonella typhimurium to the region between trpD and supD.
Microbial pathogenesis 1986;1(2):115-24.
1986: Benjamin W H; Turnbough C L; Posey B S; Briles D E
Salmonella typhimurium virulence genes necessary to exploit the Itys/s genotype of the mouse.
Infection and immunity 1986;51(3):872-8.
1986: Briles D E; Benjamin W; Posey B; Michalek S M; McGhee J R
Independence of macrophage activation and expression of the alleles of the Ity (immunity to typhimurium) locus.
Microbial pathogenesis 1986;1(1):33-41.
1986: Briles D E; Benjamin W H; Huster W J; Posey B
Genetic approaches to the study of disease resistance: with special emphasis on the use of recombinant inbred mice.
Current topics in microbiology and immunology 1986;124():21-35.
1986: Briles D E; Horowitz J; McDaniel L S; Benjamin W H; Claflin J L; Booker C L; Scott G; Forman C
Genetic control of the susceptibility to pneumococcal infection.
Current topics in microbiology and immunology 1986;124():103-20.
1985: Benjamin W H; Turnbough C L; Posey B S; Briles D E
The ability of Salmonella typhimurium to produce the siderophore enterobactin is not a virulence factor in mouse typhoid.
Infection and immunity 1985;50(2):392-7.
1984: McDaniel L S; Benjamin W H; Forman C; Briles D E
Blood clearance by anti-phosphocholine antibodies as a mechanism of protection in experimental pneumococcal bacteremia.
Journal of immunology (Baltimore, Md. : 1950) 1984;133(6):3308-12.
1984: Briles D E; Forman C; Hudak S; Claflin J L
The effects of idiotype on the ability of IgG1 anti-phosphorylcholine antibodies to protect mice from fatal infection with Streptococcus pneumoniae.
European journal of immunology 1984;14(11):1027-30.
1984: Briles D E; Forman C; Hudak S; Claflin J L
The effects of subclass on the ability of anti-phosphocholine antibodies to protect mice from fatal infection with Streptococcus pneumoniae.
The Journal of molecular and cellular immunology : JMCI 1984;1(5):305-9.
1982: Briles D E; Forman C; Hudak S; Claflin J L
Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae.
The Journal of experimental medicine 1982;156(4):1177-85.
1982: Yother J; Forman C; Gray B M; Briles D E
Protection of mice from infection with Streptococcus pneumoniae by anti-phosphocholine antibody.
Infection and immunity 1982;36(1):184-8.
1981: Briles D E; Claflin J L; Schroer K; Forman C
Mouse Igg3 antibodies are highly protective against infection with Streptococcus pneumoniae.
Nature 1981;294(5836):88-90.

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