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Karen Briley-Saebo

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K Raman Purushothaman; Meerarani Purushothaman; Samin K Sharma; Sotirios Tsimikas; Joseph L Witztum; Karen C Briley-Saebo; Solene Evrard; Zahi A Fayad; Valentin Fuster; Annapoorna Kini; Jason C Kovacic; Prakash Krishnan; Patrick A Lento; Andrew P Levy; Pedro R Moreno
Increased expression of oxidation-specific epitopes and apoptosis are associated with haptoglobin genotype: possible implications for plaque progression in human atherosclerosis.
Karen C Briley-Saebo; Florence Casanada; Young-Seok Cho; Stephen Dickson; Zahi A Fayad; Simone Green; Gregor Leibundgut; Yury I Miller; Tuyen Hoang Nguyen; Sung Kee Ryu; Alexander M Saeboe; Walter Shaw; Eugenia Volkava; Philipp Weisner; Joseph L Witztum; Eugenia R Volkova; Philipp Wiesner; Sotirios Tsimikas
In vivo detection of oxidation-specific epitopes in atherosclerotic lesions using biocompatible manganese molecular magnetic imaging probes.
David P Cormode; Gitte O Skajaa; Amanda Delshad; Nicole Parker; Peter A Jarzyna; Claudia Calcagno; Merav W Galper; Torjus Skajaa; Karen C Briley-Saebo; Heather M Bell; Ronald E Gordon; Zahi A Fayad; Savio L C Woo; Willem J M Mulder
A versatile and tunable coating strategy allows control of nanocrystal delivery to cell types in the liver.

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All Publications

2012: K Raman Purushothaman; Meerarani Purushothaman; Samin K Sharma; Sotirios Tsimikas; Joseph L Witztum; Karen C Briley-Saebo; Solene Evrard; Zahi A Fayad; Valentin Fuster; Annapoorna Kini; Jason C Kovacic; Prakash Krishnan; Patrick A Lento; Andrew P Levy; Pedro R Moreno
Increased expression of oxidation-specific epitopes and apoptosis are associated with haptoglobin genotype: possible implications for plaque progression in human atherosclerosis.
Journal of the American College of Cardiology 2012;60(2):112-9.
2012: Karen C Briley-Saebo; Florence Casanada; Young-Seok Cho; Stephen Dickson; Zahi A Fayad; Simone Green; Gregor Leibundgut; Yury I Miller; Tuyen Hoang Nguyen; Sung Kee Ryu; Alexander M Saeboe; Walter Shaw; Eugenia Volkava; Philipp Weisner; Joseph L Witztum; Eugenia R Volkova; Philipp Wiesner; Sotirios Tsimikas
In vivo detection of oxidation-specific epitopes in atherosclerotic lesions using biocompatible manganese molecular magnetic imaging probes.
Journal of the American College of Cardiology 2012;59(6):616-26.
2011: David P Cormode; Gitte O Skajaa; Amanda Delshad; Nicole Parker; Peter A Jarzyna; Claudia Calcagno; Merav W Galper; Torjus Skajaa; Karen C Briley-Saebo; Heather M Bell; Ronald E Gordon; Zahi A Fayad; Savio L C Woo; Willem J M Mulder
A versatile and tunable coating strategy allows control of nanocrystal delivery to cell types in the liver.
Bioconjugate chemistry 2011;22(3):353-61.
2011: Karen C Briley-Saebo; Young Seok Cho; Peter X Shaw; Sung Kee Ryu; Venkatesh Mani; Stephen Dickson; Ehsan Izadmehr; Simone Green; Zahi A Fayad; Sotirios Tsimikas
Targeted iron oxide particles for in vivo magnetic resonance detection of atherosclerotic lesions with antibodies directed to oxidation-specific epitopes.
Journal of the American College of Cardiology 2011;57(3):337-47.
2010: Karen C Briley-Saebo; Marylene Leboeuf; Stephen Dickson; Venkatesh Mani; Zahi A Fayad; A Karolina Palucka; Jacques Banchereau; Miriam Merad
Longitudinal tracking of human dendritic cells in murine models using magnetic resonance imaging.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2010;64(5):1510-9.
2009: Anne Beilvert; David P Cormode; Frédéric Chaubet; Karen C Briley-Saebo; Venkatesh Mani; Willem J M Mulder; Esad Vucic; Jean-François Toussaint; Didier Letourneur; Zahi A Fayad
Tyrosine polyethylene glycol (PEG)-micelle magnetic resonance contrast agent for the detection of lipid rich areas in atherosclerotic plaque.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2009;62(5):1195-201.
2009: Eric D Adler; Anne Bystrup; Karen C Briley-Saebo; Venkatesh Mani; Wilson Young; Steven Giovanonne; Perry Altman; Steven J Kattman; Joseph A Frank; Hanns-Joachim Weinmann; Gordon M Keller; Zahi A Fayad
In vivo detection of embryonic stem cell-derived cardiovascular progenitor cells using Cy3-labeled Gadofluorine M in murine myocardium.
JACC. Cardiovascular imaging 2009;2(9):1114-22.
2009: Zahi A Fayad; Louai Razzouk; Karen C Briley-Saebo; Venkatesh Mani
Iron oxide magnetic resonance imaging for atherosclerosis therapeutic evaluation: still "rusty?".
Journal of the American College of Cardiology 2009;53(22):2051-2.
2009: David P Cormode; Rohith Chandrasekar; Amanda Delshad; Karen C Briley-Saebo; Claudia Calcagno; Alessandra Barazza; Willem J M Mulder; Edward A Fisher; Zahi A Fayad
Comparison of synthetic high density lipoprotein (HDL) contrast agents for MR imaging of atherosclerosis.
Bioconjugate chemistry 2009;20(5):937-43.
2009: Karen C Briley-Saebo; Simonetta Geninatti Crich; David P Cormode; Alessandra Barazza; Willem J M Mulder; Wei Chen; Giovanni B Giovenzana; Edward A Fisher; Silvio Aime; Zahi A Fayad
High-relaxivity gadolinium-modified high-density lipoproteins as magnetic resonance imaging contrast agents.
The journal of physical chemistry. B 2009;113(18):6283-9.
2009: Michael Lipinski; Juan C Frias; Vardan Amirbekian; Karen C Briley-Saebo; Venkatesh Mani; Daniel Samber; Antonio Abbate; Juan Gilberto S Aguinaldo; Davis Massey; Valentin Fuster; George W Vetrovec; Zahi A Fayad
Macrophage-specific lipid-based nanoparticles improve cardiac magnetic resonance detection and characterization of human atherosclerosis.
JACC. Cardiovascular imaging 2009;2(5):637-47.
2008: David P Cormode; Karen C Briley-Saebo; Willem J M Mulder; Juan Gilberto S Aguinaldo; Alessandra Barazza; Yanqing Ma; Edward A Fisher; Zahi A Fayad
An ApoA-I mimetic peptide high-density-lipoprotein-based MRI contrast agent for atherosclerotic plaque composition detection.
Small (Weinheim an der Bergstrasse, Germany) 2008;4(9):1437-44.
2008: Michael Lipinski; Karen C Briley-Saebo; Venkatesh Mani; zahi Fayad
"Positive contrast" inversion-recovery with ON[corrected]-resonant water suppression magnetic resonance imaging: a change for the better?
Journal of the American College of Cardiology 2008;52(6):492-4.
2008: Venkatesh Mani; Eric Adler; Karen C Briley-Saebo; Anne Bystrup; Valentin Fuster; Gordon Keller; zahi Fayad
Serial in vivo positive contrast MRI of iron oxide-labeled embryonic stem cell-derived cardiac precursor cells in a mouse model of myocardial infarction.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2008;60(1):73-81.
2008: Claudia Calcagno; Jean-Christophe Cornily; Fabien Hyafil; James Rudd; Karen C Briley-Saebo; Venkatesh Mani; Gregg Goldschlager; Josef Machac; Valentin Fuster; zahi Fayad
Detection of neovessels in atherosclerotic plaques of rabbits using dynamic contrast enhanced MRI and 18F-FDG PET.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(7):1311-7.
2008: Karen C Briley-Saebo; Peter X Shaw; Willem J M Mulder; Seung-Hyuk Choi; Esad Vucic; Juan Gilberto S Aguinaldo; Joseph L Witztum; Valentin Fuster; Sotirios Tsimikas; zahi Fayad
Targeted molecular probes for imaging atherosclerotic lesions with magnetic resonance using antibodies that recognize oxidation-specific epitopes.
Circulation 2008;117(25):3206-15.
2008: Jean-Christophe Cornily; Fabien Hyafil; Claudia Calcagno; Karen C Briley-Saebo; James Tunstead; Juan Gilberto S Aguinaldo; Venkatesh Mani; Vito Lorusso; Friedrich M Cavagna; zahi Fayad
Evaluation of neovessels in atherosclerotic plaques of rabbits using an albumin-binding intravascular contrast agent and MRI.
Journal of magnetic resonance imaging : JMRI 2008;27(6):1406-11.
2008: Karen C Briley-Saebo; Venkatesh Mani; Fabien Hyafil; Jean-Christophe Cornily; zahi Fayad
Fractionated Feridex and positive contrast: in vivo MR imaging of atherosclerosis.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2008;59(4):721-30.
2007: Karen C Briley-Saebo; Willem J M Mulder; Venkatesh Mani; Fabien Hyafil; Vardan Amirbekian; Juan Gilberto S Aguinaldo; Edward A Fisher; zahi Fayad
Magnetic resonance imaging of vulnerable atherosclerotic plaques: current imaging strategies and molecular imaging probes.
Journal of magnetic resonance imaging : JMRI 2007;26(3):460-79.
2007: Vardan Amirbekian; Michael Lipinski; Karen C Briley-Saebo; Smbat Amirbekian; Juan Gilberto S Aguinaldo; David B Weinreb; Esad Vucic; Juan C Frias; Fabien Hyafil; Venkatesh Mani; Edward A Fisher; zahi Fayad
Detecting and assessing macrophages in vivo to evaluate atherosclerosis noninvasively using molecular MRI.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(3):961-6.
2006: Karen C Briley-Saebo; Vardan Amirbekian; Venkatesh Mani; Juan Gilberto S Aguinaldo; Esad Vucic; David Carpenter; Smbat Amirbekian; zahi Fayad
Gadolinium mixed-micelles: effect of the amphiphile on in vitro and in vivo efficacy in apolipoprotein E knockout mouse models of atherosclerosis.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;56(6):1336-46.
2006: Venkatesh Mani; Karen C Briley-Saebo; Fabien Hyafil; zahi Fayad
Feasibility of in vivo identification of endogenous ferritin with positive contrast MRI in rabbit carotid crush injury using GRASP.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;56(5):1096-106.
2006: Michael Lipinski; Vardan Amirbekian; Juan C Frias; Juan Gilberto S Aguinaldo; Venkatesh Mani; Karen C Briley-Saebo; Valentin Fuster; John T Fallon; Edward A Fisher; zahi Fayad
MRI to detect atherosclerosis with gadolinium-containing immunomicelles targeting the macrophage scavenger receptor.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;56(3):601-10.
2006: Karen C Briley-Saebo; Lars O Johansson; Svein Olaf Hustvedt; Anita G Haldorsen; Atle Bjørnerud; zahi Fayad; Haakan K Ahlstrom
Clearance of iron oxide particles in rat liver: effect of hydrated particle size and coating material on liver metabolism.
Investigative radiology 2006;41(7):560-71.
2006: Venkatesh Mani; Karen C Briley-Saebo; Vitalii V Itskovich; Daniel D Samber; zahi Fayad
Gradient echo acquisition for superparamagnetic particles with positive contrast (GRASP): sequence characterization in membrane and glass superparamagnetic iron oxide phantoms at 1.5T and 3T.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;55(1):126-35.
2004: Karen C Briley-Saebo; Atle Bjørnerud; Derek Grant; Håkan Ahlstrom; Trond Berg; Grete Mørk Kindberg
Hepatic cellular distribution and degradation of iron oxide nanoparticles following single intravenous injection in rats: implications for magnetic resonance imaging.
Cell and tissue research 2004;316(3):315-23.
2004: Rolf Eriksson; Lars Johansson; Tomas Bjerner; Karen C Briley-Saebo; Håkan Ahlström
Uptake of MnCl2 and mangafodipir trisodium in the myocardium: a magnetic resonance imaging study in pigs.
Journal of magnetic resonance imaging : JMRI 2004;19(5):564-9.
2003: Silke Aumann; Stefan O Schoenberg; Armin Just; Karen C Briley-Saebo; Atle Bjørnerud; Michael Bock; Gunnar Brix
Quantification of renal perfusion using an intravascular contrast agent (part 1): results in a canine model.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2003;49(2):276-87.