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Michèle Brillard-Bourdet

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Genes & Molecular Sequences

Amino Acid Sequences

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Timofey Kalupov; Michèle Brillard-Bourdet; Sébastien Dadé; Hélène Serrano; Julien Wartelle; Nicolas Guyot; Luiz Juliano; Thierry Moreau; Azzaq Belaaouaj; Francis Gauthier
Structural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: relevance to mouse models of human inflammatory diseases.
Brice Korkmaz; Eric Hajjar; Timofey Kalupov; Nathalie Reuter; Michèle Brillard-Bourdet; Thierry Moreau; Luiz Juliano; Francis Gauthier
Influence of charge distribution at the active site surface on the substrate specificity of human neutrophil protease 3 and elastase. A kinetic and molecular modeling analysis.
Michèle Brillard-Bourdet; Ahmed Hamdaoui; Eric Hajjar; Christian Boudier; Nathalie Reuter; Laurence Ehret-Sabatier; Joseph G Bieth; Francis Gauthier
A novel locust (Schistocerca gregaria) serine protease inhibitor with a high affinity for neutrophil elastase.

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All Publications

2009: Timofey Kalupov; Michèle Brillard-Bourdet; Sébastien Dadé; Hélène Serrano; Julien Wartelle; Nicolas Guyot; Luiz Juliano; Thierry Moreau; Azzaq Belaaouaj; Francis Gauthier
Structural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: relevance to mouse models of human inflammatory diseases.
The Journal of biological chemistry 2009;284(49):34084-91.
2007: Brice Korkmaz; Eric Hajjar; Timofey Kalupov; Nathalie Reuter; Michèle Brillard-Bourdet; Thierry Moreau; Luiz Juliano; Francis Gauthier
Influence of charge distribution at the active site surface on the substrate specificity of human neutrophil protease 3 and elastase. A kinetic and molecular modeling analysis.
The Journal of biological chemistry 2007;282(3):1989-97.
2006: Michèle Brillard-Bourdet; Ahmed Hamdaoui; Eric Hajjar; Christian Boudier; Nathalie Reuter; Laurence Ehret-Sabatier; Joseph G Bieth; Francis Gauthier
A novel locust (Schistocerca gregaria) serine protease inhibitor with a high affinity for neutrophil elastase.
The Biochemical journal 2006;400(3):467-76.
2006: Nathalie Heuzé-Vourc'h; Mireille Aïnciburu; Chris Planque; Michèle Brillard-Bourdet; Catherine Ott; Colette Jolivet-Reynaud; Yves Courty
Recombinant kallikrein expression: site-specific integration for hK6 production in human cells.
Biological chemistry 2006;387(6):687-95.
2004: Frédéric Bourgeon; Bertrand Evrard; Michèle Brillard-Bourdet; Daniel Colleu; Bernard Jégou; Charles Pineau
Involvement of semenogelin-derived peptides in the antibacterial activity of human seminal plasma.
Biology of reproduction 2004;70(3):768-74.
2002: Brice Korkmaz; Sylvie Attucci; Eric Hazouard; Martine Ferrandiere; Marie-Lise Jourdan; Michèle Brillard-Bourdet; Luiz Juliano; Francis Gauthier
Discriminating between the activities of human neutrophil elastase and proteinase 3 using serpin-derived fluorogenic substrates.
The Journal of biological chemistry 2002;277(42):39074-81.
2002: Sylvie Attucci; Brice Korkmaz; Luiz Juliano; Eric Hazouard; Catherine Girardin; Michèle Brillard-Bourdet; Sophie Réhault; Philippe Anthonioz; Francis Gauthier
Measurement of free and membrane-bound cathepsin G in human neutrophils using new sensitive fluorogenic substrates.
The Biochemical journal 2002;366(Pt 3):965-70.
2002: Sophie Réhault; Michèle Brillard-Bourdet; Luc Bourgeois; Gilles Frenette; Luiz Juliano; Francis Gauthier; Thierry Moreau
Design of new and sensitive fluorogenic substrates for human kallikrein hK3 (prostate-specific antigen) derived from semenogelin sequences.
Biochimica et biophysica acta 2002;1596(1):55-62.
2002: Michèle Brillard-Bourdet; Sophie Réhault; Luiz Juliano; Michèle Ferrer; Thierry Moreau; Francis Gauthier
Amidolytic activity of prostatic acid phosphatase on human semenogelins and semenogelin-derived synthetic substrates.
European journal of biochemistry / FEBS 2002;269(1):390-5.
2001: Marie-Louise Zani; Michèle Brillard-Bourdet; C Lazure; Luiz Juliano; Yves Courty; Francis Gauthier; Thierry Moreau
Purification and characterization of active recombinant rat kallikrein rK9.
Biochimica et biophysica acta 2001;1547(2):387-96.
1999: Sophie Réhault; Michèle Brillard-Bourdet; Maria A Juliano; Luiz Juliano; Francis Gauthier; Thierry Moreau
New, sensitive fluorogenic substrates for human cathepsin G based on the sequence of serpin-reactive site loops.
The Journal of biological chemistry 1999;274(20):13810-7.
1998: Michèle Brillard-Bourdet; V Nguyên; M Ferrer-di Martino; Francis Gauthier; Thierry Moreau
Purification and characterization of a new cystatin inhibitor from Taiwan cobra (Naja naja atra) venom.
The Biochemical journal 1998;331 ( Pt 1)():239-44.
1997: L Bourgeois; Michèle Brillard-Bourdet; D Deperthes; Maria A Juliano; Luiz Juliano; Roland R Tremblay; JY Dubé; Francis Gauthier
Serpin-derived peptide substrates for investigating the substrate specificity of human tissue kallikreins hK1 and hK2.
The Journal of biological chemistry 1997;272(47):29590-5.
1997: A El Moujahed; Michèle Brillard-Bourdet; Maria A Juliano; Thierry Moreau; Jair R Chagas; N Gutman; E S Prado; Francis Gauthier
Kininogen-derived fluorogenic substrates for investigating the vasoactive properties of rat tissue kallikreins--identification of a T-kinin-releasing rat kallikrein.
European journal of biochemistry / FEBS 1997;247(2):652-8.
1996: D Deperthes; Gilles Frenette; Michèle Brillard-Bourdet; L Bourgeois; Francis Gauthier; Roland R Tremblay; JY Dubé
Potential involvement of kallikrein hK2 in the hydrolysis of the human seminal vesicle proteins after ejaculation.
Journal of andrology 1996;17(6):659-65.
1995: Gilles Lalmanach; Carole Serveau; Michèle Brillard-Bourdet; Jair R Chagas; R Mayer; Luiz Juliano; Francis Gauthier
Conserved cystatin segments as models for designing specific substrates and inhibitors of cysteine proteinases.
Journal of protein chemistry 1995;14(8):645-53.
1995: L E Avril; M di Martino-Ferrer; Michèle Brillard-Bourdet; Francis Gauthier
Inhibition of U-937 membrane-associated cathepsin G by GP120 (IIIB) and V3 loop-derived peptides from several strains of HIV-1.
FEBS letters 1995;367(3):251-6.
1995: Thierry Moreau; Michèle Brillard-Bourdet; Jair R Chagas; Francis Gauthier
Pro-rat atrial natriuretic peptide-mimicking peptides as substrates for rat kallikreins rK2 (tonin) and rK9.
Biochimica et biophysica acta 1995;1249(2):168-72.
1995: Michèle Brillard-Bourdet; Thierry Moreau; Francis Gauthier
Substrate specificity of tissue kallikreins: importance of an extended interaction site.
Biochimica et biophysica acta 1995;1246(1):47-52.
1993: Francis Gauthier; Thierry Moreau; Gilles Lalmanach; Michèle Brillard-Bourdet; M Ferrer-Di Martino; Luiz Juliano
A new, sensitive fluorogenic substrate for papain based on the sequence of the cystatin inhibitory site.
Archives of biochemistry and biophysics 1993;306(2):304-8.
1993: Gilles Lalmanach; Johan Hoebeke; Thierry Moreau; Michèle Brillard-Bourdet; M Ferrer-Ditt Martino; F Borras-Cuesta; Francis Gauthier
Interaction between cystatin-derived peptides and papain.
Journal of protein chemistry 1993;12(1):23-31.
1992: Thierry Moreau; Michèle Brillard-Bourdet; J Bouhnik; Francis Gauthier
Protein products of the rat kallikrein gene family. Substrate specificities of kallikrein rK2 (tonin) and kallikrein rK9.
The Journal of biological chemistry 1992;267(14):10045-51.
1992: Francis Gauthier; Thierry Moreau; N Gutman; A el Moujahed; Michèle Brillard-Bourdet
Functional diversity of proteinases encoded by genes of the rat tissue kallikrein family.
Agents and actions. Supplements 1992;38 ( Pt 1)():42-50.