Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Constance Brinckerhoff

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Physiology

Living Beings

Rabbits

Anatomy

Concepts & Ideas

Molecular Sequence Data

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
16
Coon, Charles
16
Vincenti, Matthew
15
Benbow, Ulrike
11
Rutter, Joni
9
Mitchell, TI
6
Mix, Kimberlee
6
Sporn, Michael B.
5
Sun, Yubo
5
Tower, Grant
5
Wyatt, Colby
5
Mengshol, John
5
Fini, Elizabeth
4
Burrage, Peter
3
Cheung, Herman
3
Wenger, Leonor

Sign-in to see all Coauthors

Publications

TOP 3
Eck Sarah M; Blackburn Jessica S; Schmucker Adam C; Burrage Peter S; Brinckerhoff Constance E
Matrix metalloproteinase and G protein coupled receptors: co-conspirators in the pathogenesis of autoimmune disease and cancer.
Coon Charles I; Fiering Steven; Gaudet Justin; Wyatt Colby A; Brinckerhoff Constance E
Site controlled transgenic mice validating increased expression from human matrix metalloproteinase (MMP-1) promoter due to a naturally occurring SNP.
Eck Sarah M; Côté Anik L; Winkelman William D; Brinckerhoff Constance E
CXCR4 and matrix metalloproteinase-1 are elevated in breast carcinoma-associated fibroblasts and in normal mammary fibroblasts exposed to factors secreted by breast cancer cells.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Constance Brinckerhoff (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Eck Sarah M; Blackburn Jessica S; Schmucker Adam C; Burrage Peter S; Brinckerhoff Constance E
Matrix metalloproteinase and G protein coupled receptors: co-conspirators in the pathogenesis of autoimmune disease and cancer.
Journal of autoimmunity 2009;33(3-4):214-21.
2009: Coon Charles I; Fiering Steven; Gaudet Justin; Wyatt Colby A; Brinckerhoff Constance E
Site controlled transgenic mice validating increased expression from human matrix metalloproteinase (MMP-1) promoter due to a naturally occurring SNP.
Matrix biology : journal of the International Society for Matrix Biology 2009;28(7):425-31.
2009: Eck Sarah M; Côté Anik L; Winkelman William D; Brinckerhoff Constance E
CXCR4 and matrix metalloproteinase-1 are elevated in breast carcinoma-associated fibroblasts and in normal mammary fibroblasts exposed to factors secreted by breast cancer cells.
Molecular cancer research : MCR 2009;7(7):1033-44.
2009: Petrella Brenda L; Brinckerhoff Constance E
PTEN suppression of YY1 induces HIF-2 activity in von hippel lindau null renal cell carcinoma.
Cancer biology & therapy 2009;8(14):1389-401.
2009: Eck S M; Hoopes P J; Petrella B L; Coon C I; Brinckerhoff C E
Matrix metalloproteinase-1 promotes breast cancer angiogenesis and osteolysis in a novel in vivo model.
Breast cancer research and treatment 2009;116(1):79-90.
2009: Blackburn Jessica S; Brinckerhoff Constance E
Wild-type versus mutant MMP-8 in melanoma: 'when you come to a fork in the road, take it'.
Pigment cell & melanoma research 2009;22(3):248-50.
2009: Li Jinju; Ghio Andrew J; Cho Seung-Hyun; Brinckerhoff Constance E; Simon Sidney A; Liedtke Wolfgang
Diesel exhaust particles activate the matrix-metalloproteinase-1 gene in human bronchial epithelia in a beta-arrestin-dependent manner via activation of RAS.
Environmental health perspectives 2009;117(3):400-9.
2008: Blackburn Jessica S; Brinckerhoff Constance E
Matrix metalloproteinase-1 and thrombin differentially activate gene expression in endothelial cells via PAR-1 and promote angiogenesis.
The American journal of pathology 2008;173(6):1736-46.
2008: Burrage Peter S; Schmucker Adam C; Ren Yanqing; Sporn Michael B; Brinckerhoff Constance E
Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression.
Arthritis research & therapy 2008;10(6):R139.
2007: Blackburn Jessica S; Rhodes C Harker; Coon Charles I; Brinckerhoff Constance E
RNA interference inhibition of matrix metalloproteinase-1 prevents melanoma metastasis by reducing tumor collagenase activity and angiogenesis.
Cancer research 2007;67(22):10849-58.
2007: Vincenti Matthew P; Brinckerhoff Constance E
Signal transduction and cell-type specific regulation of matrix metalloproteinase gene expression: can MMPs be good for you?
Journal of cellular physiology 2007;213(2):355-64.
2007: Burrage Peter S; Huntington Jonathan T; Sporn Michael B; Brinckerhoff Constance E
Regulation of matrix metalloproteinase gene expression by a retinoid X receptor-specific ligand.
Arthritis and rheumatism 2007;56(3):892-904.
2007: Mix Kimberlee S; Attur Mukundan G; Al-Mussawir Hayf; Abramson Steven B; Brinckerhoff Constance E; Murphy Evelyn P
Transcriptional repression of matrix metalloproteinase gene expression by the orphan nuclear receptor NURR1 in cartilage.
The Journal of biological chemistry 2007;282(13):9492-504.
2006: Petrella Brenda L; Brinckerhoff Constance E
Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase.
Molecular cancer 2006;5():66.
2006: Burrage Peter S; Mix Kimberlee S; Brinckerhoff Constance E
Matrix metalloproteinases: role in arthritis.
Frontiers in bioscience : a journal and virtual library 2006;11():529-43.
2005: Wyatt Colby A; Geoghegan James C; Brinckerhoff Constance E
Short hairpin RNA-mediated inhibition of matrix metalloproteinase-1 in MDA-231 cells: effects on matrix destruction and tumor growth.
Cancer research 2005;65(23):11101-8.
2005: Petrella Brenda L; Lohi Jouko; Brinckerhoff Constance E
Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2 alpha in von Hippel-Lindau renal cell carcinoma.
Oncogene 2005;24(6):1043-52.
2004: Beehler Blake C; Brinckerhoff Constance E; Ostrowski Jacek
Selective retinoic acid receptor ligands for rheumatoid arthritis.
Current opinion in investigational drugs (London, England : 2000) 2004;5(11):1153-7.
2004: Mix Kimberlee S; Sporn Michael B; Brinckerhoff Constance E; Eyre David; Schurman David J
Novel inhibitors of matrix metalloproteinase gene expression as potential therapies for arthritis.
Clinical orthopaedics and related research 2004;(427 Suppl):S129-37.
2004: Huntington Jonathan T; Shields Janiel M; Der Channing J; Wyatt Colby A; Benbow Ulrike; Slingluff Craig L; Brinckerhoff Constance E
Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling.
The Journal of biological chemistry 2004;279(32):33168-76.
2004: Mix Kimberlee S; Coon Charles I; Rosen Evan D; Suh Nanjoo; Sporn Michael B; Brinckerhoff Constance E
Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling.
Molecular pharmacology 2004;65(2):309-18.
2003: Tower Grant B; Coon Charles I; Brinckerhoff Constance E
The 2G single nucleotide polymorphism (SNP) in the MMP-1 promoter contributes to high levels of MMP-1 transcription in MCF-7/ADR breast cancer cells.
Breast cancer research and treatment 2003;82(2):75-82.
2003: Tower Grant B; Coon Charles I; Belguise Karine; Chalbos Dany; Brinckerhoff Constance E
Fra-1 targets the AP-1 site/2G single nucleotide polymorphism (ETS site) in the MMP-1 promoter.
European journal of biochemistry / FEBS 2003;270(20):4216-25.
2003: Brinckerhoff Constance E; Sporn Michael B
Retinoids and rexinoids for the 21st century: a brave new world for arthritis.
The Journal of rheumatology 2003;30(2):211-3.
2002: Wyatt Colby A; Coon Charles I; Gibson Jennifer J; Brinckerhoff Constance E
Potential for the 2G single nucleotide polymorphism in the promoter of matrix metalloproteinase to enhance gene expression in normal stromal cells.
Cancer research 2002;62(24):7200-2.
2002: Tower Grant B; Coon Charles C; Benbow Ulrike; Vincenti Matthew P; Brinckerhoff Constance E
Erk 1/2 differentially regulates the expression from the 1G/2G single nucleotide polymorphism in the MMP-1 promoter in melanoma cells.
Biochimica et biophysica acta 2002;1586(3):265-74.
2002: Brinckerhoff Constance E; Matrisian Lynn M
Matrix metalloproteinases: a tail of a frog that became a prince.
Nature reviews. Molecular cell biology 2002;3(3):207-14.
2002: Mengshol John A; Mix Kimberlee S; Brinckerhoff Constance E
Matrix metalloproteinases as therapeutic targets in arthritic diseases: bull's-eye or missing the mark?
Arthritis and rheumatism 2002;46(1):13-20.
2002: Tobin Stephen W; Douville Karen; Benbow Ulrike; Brinckerhoff Constance E; Memoli Vincent A; Arrick Bradley A
Consequences of altered TGF-beta expression and responsiveness in breast cancer: evidence for autocrine and paracrine effects.
Oncogene 2002;21(1):108-18.
2002: Sun Yubo; Wenger Leonor; Brinckerhoff Constance E; Misra Ravi R; Cheung Herman S
Basic calcium phosphate crystals induce matrix metalloproteinase-1 through the Ras/mitogen-activated protein kinase/c-Fos/AP-1/metalloproteinase 1 pathway. Involvement of transcription factor binding sites AP-1 and PEA-3.
The Journal of biological chemistry 2002;277(2):1544-52.
2002: Benbow Ulrike; Tower Grant B; Wyatt Colby A; Buttice Giovanna; Brinckerhoff Constance E
High levels of MMP-1 expression in the absence of the 2G single nucleotide polymorphism is mediated by p38 and ERK1/2 mitogen-activated protein kinases in VMM5 melanoma cells.
Journal of cellular biochemistry 2002;86(2):307-19.
2002: Vincenti Matthew P; Brinckerhoff Constance E
Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors.
Arthritis research 2002;4(3):157-64.
2001: Mengshol J A; Vincenti M P; Brinckerhoff C E
IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways.
Nucleic acids research 2001;29(21):4361-72.
2001: Vincenti M P; Brinckerhoff C E
The potential of signal transduction inhibitors for the treatment of arthritis: Is it all just JNK?
The Journal of clinical investigation 2001;108(2):181-3.
2001: Mix K S; Mengshol J A; Benbow U; Vincenti M P; Sporn M B; Brinckerhoff C E
A synthetic triterpenoid selectively inhibits the induction of matrix metalloproteinases 1 and 13 by inflammatory cytokines.
Arthritis and rheumatism 2001;44(5):1096-104.
2001: Ranganathan A C; Nelson K K; Rodriguez A M; Kim K H; Tower G B; Rutter J L; Brinckerhoff C E; Huang T T; Epstein C J; Jeffrey J J; Melendez J A
Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation.
The Journal of biological chemistry 2001;276(17):14264-70.
2001: Noll W W; Belloni D R; Rutter J L; Storm C A; Schned A R; Titus-Ernstoff L; Ernstoff M S; Brinckerhoff C E
Loss of heterozygosity on chromosome 11q22-23 in melanoma is associated with retention of the insertion polymorphism in the matrix metalloproteinase-1 promoter.
The American journal of pathology 2001;158(2):691-7.
2001: Vincenti M P; Brinckerhoff C E
Early response genes induced in chondrocytes stimulated with the inflammatory cytokine interleukin-1beta.
Arthritis research 2001;3(6):381-8.
2000: Brinckerhoff C E; Rutter J L; Benbow U
Interstitial collagenases as markers of tumor progression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(12):4823-30.
2000: Benbow U; Orndorff K A; Brinckerhoff C E; Givan A L
Confocal assay for invasion: use of propidium iodide fluorescence and laser reflectance to quantify the rate of migration of cells through a matrix.
Cytometry 2000;40(4):253-9.
2000: Mengshol J A; Vincenti M P; Coon C I; Barchowsky A; Brinckerhoff C E
Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3.
Arthritis and rheumatism 2000;43(4):801-11.
2000: White L A; Mitchell T I; Brinckerhoff C E
Transforming growth factor beta inhibitory element in the rabbit matrix metalloproteinase-1 (collagenase-1) gene functions as a repressor of constitutive transcription.
Biochimica et biophysica acta 2000;1490(3):259-68.
1999: Benbow U; Schoenermark M P; Mitchell T I; Rutter J L; Shimokawa K; Nagase H; Brinckerhoff C E
A novel host/tumor cell interaction activates matrix metalloproteinase 1 and mediates invasion through type I collagen.
The Journal of biological chemistry 1999;274(36):25371-8.
1999: Benbow U; Maitra R; Hamilton J W; Brinckerhoff C E
Selective inhibition of collagenase-1, gelatinase A, and gelatinase B by chemotherapeutic agents.
Annals of the New York Academy of Sciences 1999;878():662-4.
1999: Sun Y; Sun Y; Wenger L; Rutter J L; Brinckerhoff C E; Cheung H S
Human metalloproteinase-1 (collagenase-1) is a tumor suppressor protein p53 target gene.
Annals of the New York Academy of Sciences 1999;878():638-41.
1999: Schoenermark M P; Mitchell T I; Rutter J L; Reczek P R; Brinckerhoff C E
Retinoid-mediated suppression of tumor invasion and matrix metalloproteinase synthesis.
Annals of the New York Academy of Sciences 1999;878():466-86.
1999: Benbow U; Schoenermark M P; Orndorff K A; Givan A L; Brinckerhoff C E
Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid.
Clinical & experimental metastasis 1999;17(3):231-8.
1999: Sun Y; Sun Y; Wenger L; Rutter J L; Brinckerhoff C E; Cheung H S
p53 down-regulates human matrix metalloproteinase-1 (Collagenase-1) gene expression.
The Journal of biological chemistry 1999;274(17):11535-40.
1999: Benbow U; Maitra R; Hamilton J W; Brinckerhoff C E
Selective modulation of collagenase 1 gene expression by the chemotherapeutic agent doxorubicin.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(1):203-8.
1999: Benbow U; Rutter J L; Lowrey C H; Brinckerhoff C E
Transcriptional repression of the human collagenase-1 (MMP-1) gene in MDA231 breast cancer cells by all-trans-retinoic acid requires distal regions of the promoter.
British journal of cancer 1999;79(2):221-8.
1998: Rutter J L; Mitchell T I; Butticè G; Meyers J; Gusella J F; Ozelius L J; Brinckerhoff C E
A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter creates an Ets binding site and augments transcription.
Cancer research 1998;58(23):5321-5.
1998: Vincenti M P; Coon C I; Brinckerhoff C E
Nuclear factor kappaB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1beta-stimulated synovial fibroblasts.
Arthritis and rheumatism 1998;41(11):1987-94.
1998: Vincenti M P; Coon C I; Mengshol J A; Yocum S; Mitchell P; Brinckerhoff C E
Cloning of the gene for interstitial collagenase-3 (matrix metalloproteinase-13) from rabbit synovial fibroblasts: differential expression with collagenase-1 (matrix metalloproteinase-1).
The Biochemical journal 1998;331 ( Pt 1)():341-6.
1998: Vincenti M P; Schroen D J; Coon C I; Brinckerhoff C E
v-src activation of the collagenase-1 (matrix metalloproteinase-1) promoter through PEA3 and STAT: requirement of extracellular signal-regulated kinases and inhibition by retinoic acid receptors.
Molecular carcinogenesis 1998;21(3):194-204.
1997: Boyle D L; Han Z; Rutter J L; Brinckerhoff C E; Firestein G S
Posttranscriptional regulation of collagenase-1 gene expression in synoviocytes by adenosine receptor stimulation.
Arthritis and rheumatism 1997;40(10):1772-9.
1997: Rutter J L; Benbow U; Coon C I; Brinckerhoff C E
Cell-type specific regulation of human interstitial collagenase-1 gene expression by interleukin-1 beta (IL-1 beta) in human fibroblasts and BC-8701 breast cancer cells.
Journal of cellular biochemistry 1997;66(3):322-36.
1997: Schroen D J; Chen J D; Vincenti M P; Brinckerhoff C E
The nuclear receptor corepressor SMRT inhibits interstitial collagenase (MMP-1) transcription through an HRE-independent mechanism.
Biochemical and biophysical research communications 1997;237(1):52-8.
1997: Benbow U; Brinckerhoff C E
The AP-1 site and MMP gene regulation: what is all the fuss about?
Matrix biology : journal of the International Society for Matrix Biology 1997;15(8-9):519-26.
1997: White L A; Maute C; Brinckerhoff C E
ETS sites in the promoters of the matrix metalloproteinases collagenase (MMP-1) and stromelysin (MMP-3) are auxiliary elements that regulate basal and phorbol-induced transcription.
Connective tissue research 1997;36(4):321-35.
1996: Schroen D J; Brinckerhoff C E
Inhibition of rabbit collagenase (matrix metalloproteinase-1; MMP-1) transcription by retinoid receptors: evidence for binding of RARs/RXRs to the -77 AP-1 site through interactions with c-Jun.
Journal of cellular physiology 1996;169(2):320-32.
1996: Vincenti M P; Coon C I; White L A; Barchowsky A; Brinckerhoff C E
src-related tyrosine kinases regulate transcriptional activation of the interstitial collagenase gene, MMP-1, in interleukin-1-stimulated synovial fibroblasts.
Arthritis and rheumatism 1996;39(4):574-82.
1996: Schroen D J; Brinckerhoff C E
Nuclear hormone receptors inhibit matrix metalloproteinase (MMP) gene expression through diverse mechanisms.
Gene expression 1996;6(4):197-207.
1996: Vincenti M P; White L A; Schroen D J; Benbow U; Brinckerhoff C E
Regulating expression of the gene for matrix metalloproteinase-1 (collagenase): mechanisms that control enzyme activity, transcription, and mRNA stability.
Critical reviews in eukaryotic gene expression 1996;6(4):391-411.
1995: White L A; Brinckerhoff C E
Two activator protein-1 elements in the matrix metalloproteinase-1 promoter have different effects on transcription and bind Jun D, c-Fos, and Fra-2.
Matrix biology : journal of the International Society for Matrix Biology 1995;14(9):715-25.
1995: Pan L; Eckhoff C; Brinckerhoff C E
Suppression of collagenase gene expression by all-trans and 9-cis retinoic acid is ligand dependent and requires both RARs and RXRs.
Journal of cellular biochemistry 1995;57(4):575-89.
1994: Vincenti M P; Coon C I; Lee O; Brinckerhoff C E
Regulation of collagenase gene expression by IL-1 beta requires transcriptional and post-transcriptional mechanisms.
Nucleic acids research 1994;22(22):4818-27.
1994: Pan L; Brinckerhoff C E
Inhibition of collagenase gene expression in synovial fibroblasts by all-trans and 9-cis retinoic acid.
Annals of the New York Academy of Sciences 1994;732():335-47.
1994: Vincenti M P; Clark I M; Brinckerhoff C E
Using inhibitors of metalloproteinases to treat arthritis. Easier said than done?
Arthritis and rheumatism 1994;37(8):1115-26.
1993: James T W; Wagner R; White L A; Zwolak R M; Brinckerhoff C E
Induction of collagenase and stromelysin gene expression by mechanical injury in a vascular smooth muscle-derived cell line.
Journal of cellular physiology 1993;157(2):426-37.
1993: Chamberlain S H; Hemmer R M; Brinckerhoff C E
Novel phorbol ester response region in the collagenase promoter binds Fos and Jun.
Journal of cellular biochemistry 1993;52(3):337-51.
1993: Delany A M; Brinckerhoff C E
The synthetic retinoid (4-hydroxyphenyl)retinamide decreases collagen expression in vitro and in the tight-skin mouse.
Arthritis and rheumatism 1993;36(7):983-93.
1993: Mitchell T I; Jeffrey J J; Palmiter R D; Brinckerhoff C E
The acute phase reactant serum amyloid A (SAA3) is a novel substrate for degradation by the metalloproteinases collagenase and stromelysin.
Biochimica et biophysica acta 1993;1156(3):245-54.
1992: Delany A M; Brinckerhoff C E
Post-transcriptional regulation of collagenase and stromelysin gene expression by epidermal growth factor and dexamethasone in cultured human fibroblasts.
Journal of cellular biochemistry 1992;50(4):400-10.
1992: Pan L; Chamberlain S H; Auble D T; Brinckerhoff C E
Differential regulation of collagenase gene expression by retinoic acid receptors--alpha, beta and gamma.
Nucleic acids research 1992;20(12):3105-11.
1992: Brinckerhoff C E
Regulation of metalloproteinase gene expression: implications for osteoarthritis.
Critical reviews in eukaryotic gene expression 1992;2(2):145-64.
1992: Auble D T; Sirum-Connolly K L; Brinckerhoff C E
Transcriptional regulation of matrix metalloproteinase genes: role of AP-1 sequences.
Matrix (Stuttgart, Germany). Supplement 1992;1():200.
1992: Brinckerhoff C E; Sirum-Connolly K L; Karmilowicz M J; Auble D T
Expression of stromelysin and stromelysin-2 in rabbit and human fibroblasts.
Matrix (Stuttgart, Germany). Supplement 1992;1():165-75.
1991: Auble D T; Brinckerhoff C E
The AP-1 sequence is necessary but not sufficient for phorbol induction of collagenase in fibroblasts.
Biochemistry 1991;30(18):4629-35.
1991: Mitchell T I; Coon C I; Brinckerhoff C E
Serum amyloid A (SAA3) produced by rabbit synovial fibroblasts treated with phorbol esters or interleukin 1 induces synthesis of collagenase and is neutralized with specific antiserum.
The Journal of clinical investigation 1991;87(4):1177-85.
1991: Sirum-Connolly K; Brinckerhoff C E
Interleukin-1 or phorbol induction of the stromelysin promoter requires an element that cooperates with AP-1.
Nucleic acids research 1991;19(2):335-41.
1990: Brinckerhoff C E; Suzuki K; Mitchell T I; Oram F; Coon C I; Palmiter R D; Nagase H
Rabbit procollagenase synthesized and secreted by a high-yield mammalian expression vector requires stromelysin (matrix metalloproteinase-3) for maximal activation.
The Journal of biological chemistry 1990;265(36):22262-9.
1990: Brinckerhoff C E; Auble D T
Regulation of collagenase gene expression in synovial fibroblasts.
Annals of the New York Academy of Sciences 1990;580():355-74.
1989: Sirum K L; Brinckerhoff C E
Cloning of the genes for human stromelysin and stromelysin 2: differential expression in rheumatoid synovial fibroblasts.
Biochemistry 1989;28(22):8691-8.
1989: Vance B A; Kowalski C G; Brinckerhoff C E
Heat shock of rabbit synovial fibroblasts increases expression of mRNAs for two metalloproteinases, collagenase and stromelysin.
The Journal of cell biology 1989;108(6):2037-43.
1989: Brinckerhoff C E; Mitchell T I; Karmilowicz M J; Kluve-Beckerman B; Benson M D
Autocrine induction of collagenase by serum amyloid A-like and beta 2-microglobulin-like proteins.
Science (New York, N.Y.) 1989;243(4891):655-7.
1988: Brinckerhoff C E; Mitchell T I
Autocrine control of collagenase synthesis by synovial fibroblasts.
Journal of cellular physiology 1988;136(1):72-80.
1987: Fini M E; Karmilowicz M J; Ruby P L; Beeman A M; Borges K A; Brinckerhoff C E
Cloning of a complementary DNA for rabbit proactivator. A metalloproteinase that activates synovial cell collagenase, shares homology with stromelysin and transin, and is coordinately regulated with collagenase.
Arthritis and rheumatism 1987;30(11):1254-64.
1987: Fini M E; Plucinska I M; Mayer A S; Gross R H; Brinckerhoff C E
A gene for rabbit synovial cell collagenase: member of a family of metalloproteinases that degrade the connective tissue matrix.
Biochemistry 1987;26(19):6156-65.
1987: Brinckerhoff C E; Ruby P L; Austin S D; Fini M E; White H D
Molecular cloning of human synovial cell collagenase and selection of a single gene from genomic DNA.
The Journal of clinical investigation 1987;79(2):542-6.
1986: Fini M E; Gross R H; Brinckerhoff C E
Characterization of rabbit genes for synovial cell collagenase.
Arthritis and rheumatism 1986;29(11):1301-15.
1986: Fini M E; Austin S D; Holt P T; Ruby P L; Gross R H; White H D; Brinckerhoff C E
Homology between exon-containing portions of rabbit genomic clones for synovial cell collagenase and human foreskin and synovial cell mRNAs.
Collagen and related research 1986;6(3):239-48.

Sign-in to see more