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Xiaoling Yang

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Kumiko Tominaga-Yamanaka; Xiaoling Yang; Kotb Abdelmohsen; Jennifer L Martindale; Dennis D Taub; Myriam Gorospe
NF90 coordinately represses the senescence-associated secretory phenotype.
Je-Hyun Yoon; Ming Zhan; Kotb Abdelmohsen; Kevin G Becker; Supriyo De; Maite Huarte; Jennifer L Martindale; Subramanya Srikantan; Xiaoling Yang; Myriam Gorospe
LincRNA-p21 suppresses target mRNA translation.
Kotb Abdelmohsen; Kevin G Becker; Min-Ju Kang; Ashish Lal; Jennifer L Martindale; Stuart Maudsley; Sung-Soo Park; Subramanya Srikantan; Murugan Subramanian; Kumiko Tominaga; Xiaoling Yang; Yael Yaniv; Myriam Gorospe
Growth inhibition by miR-519 via multiple p21-inducing pathways.

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All Publications

2012: Kumiko Tominaga-Yamanaka; Xiaoling Yang; Kotb Abdelmohsen; Jennifer L Martindale; Dennis D Taub; Myriam Gorospe
NF90 coordinately represses the senescence-associated secretory phenotype.
Aging 2012;4(10):695-708.
2012: Je-Hyun Yoon; Ming Zhan; Kotb Abdelmohsen; Kevin G Becker; Supriyo De; Maite Huarte; Jennifer L Martindale; Subramanya Srikantan; Xiaoling Yang; Myriam Gorospe
LincRNA-p21 suppresses target mRNA translation.
Molecular cell 2012;47(4):648-55.
2012: Kotb Abdelmohsen; Kevin G Becker; Min-Ju Kang; Ashish Lal; Jennifer L Martindale; Stuart Maudsley; Sung-Soo Park; Subramanya Srikantan; Murugan Subramanian; Kumiko Tominaga; Xiaoling Yang; Yael Yaniv; Myriam Gorospe
Growth inhibition by miR-519 via multiple p21-inducing pathways.
Molecular and cellular biology 2012;32(13):2530-48.
2012: Eun Kyung Lee; Jennifer L Martindale; Evi M Mercken; Hideyuki Okano; Nora I Perrone-Bizzozero; Sarah S Subaran; Kumiko Tominaga; Xiaoling Yang; Wado Akamatsu; Olga D Carlson; Rafael de Cabo; Josephine M Egan; Wook Kim; Rohit N Kulkarni; Myriam Gorospe
RNA-binding protein HuD controls insulin translation.
Molecular cell 2012;45(6):826-35.
2011: Kotb Abdelmohsen; Kevin G Becker; France Carrier; Min-Ju Kang; Mihee M Kim; Eun Kyung Lee; Jennifer L Martindale; Roza Selimyan; Subramanya Srikantan; Kumiko Tominaga; Xiaoling Yang; Ming Zhan; Myriam Gorospe
Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs.
Nucleic acids research 2011;39(19):8513-30.
2011: Kiyoshi Masuda; Kotb Abdelmohsen; Mihee M Kim; Subramanya Srikantan; Eun Kyung Lee; Kumiko Tominaga; Roza Selimyan; Jennifer L Martindale; Xiaoling Yang; Elin Lehrmann; Yongqing Zhang; Kevin G Becker; Jian-Ying Wang; Hyeon Ho Kim; Myriam Gorospe
Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation.
The EMBO journal 2011;30(6):1040-53.
2010: Eun Kyung Lee; Hyeon Ho Kim; Yuki Kuwano; Kotb Abdelmohsen; Subramanya Srikantan; Sarah S Subaran; Marc Gleichmann; Mohamed R Mughal; Jennifer L Martindale; Xiaoling Yang; Paul F Worley; Mark P Mattson; Myriam Gorospe
hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies.
Nature structural & molecular biology 2010;17(6):732-9.
2010: Yuki Kuwano; Rudolf Pullmann; Bernard S Marasa; Kotb Abdelmohsen; Eun Kyung Lee; Xiaoling Yang; Jennifer L Martindale; Ming Zhan; Myriam Gorospe
NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif.
Nucleic acids research 2010;38(1):225-38.
2009: Kotb Abdelmohsen; Subramanya Srikantan; Xiaoling Yang; Ashish Lal; Hyeon Ho Kim; Yuki Kuwano; Stefanie Galban; Kevin G Becker; Davida Kamara; Rafael de Cabo; Myriam Gorospe
Ubiquitin-mediated proteolysis of HuR by heat shock.
The EMBO journal 2009;28(9):1271-82.
2009: Bernard S Marasa; Subramanya Srikantan; Kiyoshi Masuda; Kotb Abdelmohsen; Yuki Kuwano; Xiaoling Yang; Jennifer L Martindale; Carrie W Rinker-Schaeffer; Myriam Gorospe
Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs.
Science signaling 2009;2(94):ra69.
2008: Hyeon Ho Kim; Kotb Abdelmohsen; Ashish Lal; Rudolf Pullmann; Xiaoling Yang; Stefanie Galban; Subramanya Srikantan; Jennifer L Martindale; Justin D Blethrow; Kevan M Shokat; Myriam Gorospe
Nuclear HuR accumulation through phosphorylation by Cdk1.
Genes & development 2008;22(13):1804-15.
2008: Yuki Kuwano; Hyeon Ho Kim; Kotb Abdelmohsen; Rudolf Pullmann; Jennifer L Martindale; Xiaoling Yang; Myriam Gorospe
MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90.
Molecular and cellular biology 2008;28(14):4562-75.
2008: Ashish Lal; Hyeon Ho Kim; Kotb Abdelmohsen; Yuki Kuwano; Rudolf Pullmann; Subramanya Srikantan; Ramesh Subrahmanyam; Jennifer L Martindale; Xiaoling Yang; Fariyal Ahmed; Francisco Navarro; Derek M. Dykxhoorn; Judy Lieberman; Myriam Gorospe
p16(INK4a) translation suppressed by miR-24.
PloS one 2008;3(3):e1864.
2008: Stefanie Galban; Yuki Kuwano; Rudolf Pullmann; Jennifer L Martindale; Hyeon Ho Kim; Ashish Lal; Kotb Abdelmohsen; Xiaoling Yang; Yongjun Dang; Jun O Liu; Stephen Lewis; Martin Holcik; Myriam Gorospe
RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha.
Molecular and cellular biology 2008;28(1):93-107.
2007: Rudolf Pullmann; Hyeon Ho Kim; Kotb Abdelmohsen; Ashish Lal; Jennifer L Martindale; Xiaoling Yang; Myriam Gorospe
Analysis of turnover and translation regulatory RNA-binding protein expression through binding to cognate mRNAs.
Molecular and cellular biology 2007;27(18):6265-78.
2007: Kotb Abdelmohsen; Rudolf Pullmann; Ashish Lal; Hyeon Ho Kim; Stefanie Galban; Xiaoling Yang; Justin D Blethrow; Mark Walker; Jonathan Shubert; David A Gillespie; Henry Furneaux; Myriam Gorospe
Phosphorylation of HuR by Chk2 regulates SIRT1 expression.
Molecular cell 2007;25(4):543-57.
2006: Ashish Lal; Kotb Abdelmohsen; Rudolf Pullmann; Tomoko Kawai; Stefanie Galban; Xiaoling Yang; Gary Brewer; Myriam Gorospe
Posttranscriptional derepression of GADD45alpha by genotoxic stress.
Molecular cell 2006;22(1):117-28.
2006: Tomoko Kawai; Ashish Lal; Xiaoling Yang; Stefanie Galban; Krystyna Mazan-Mamczarz; Myriam Gorospe
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR.
Molecular and cellular biology 2006;26(8):3295-307.
2006: JINSHUI FAN; Ming Zhan; Jikui Shen; Jennifer L Martindale; Xiaoling Yang; Tomoko Kawai; Myriam Gorospe
En masse nascent transcription analysis to elucidate regulatory transcription factors.
Nucleic acids research 2006;34(5):1492-500.
2005: Isabel López De Silanes; Stefanie Galban; Jennifer L Martindale; Xiaoling Yang; Krystyna Mazan-Mamczarz; Fred E Indig; Geppino Falco; Ming Zhan; Myriam Gorospe
Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1.
Molecular and cellular biology 2005;25(21):9520-31.
2005: Ashish Lal; Tomoko Kawai; Xiaoling Yang; Krystyna Mazan-Mamczarz; Myriam Gorospe
Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha.
The EMBO journal 2005;24(10):1852-62.
2005: Wengong Wang; Jennifer L Martindale; Xiaoling Yang; Francis J Chrest; Myriam Gorospe
Increased stability of the p16 mRNA with replicative senescence.
EMBO reports 2005;6(2):158-64.
2004: Xiaoling Yang; Wengong Wang; JINSHUI FAN; Ashish Lal; Dongmei Yang; Heping Cheng; Myriam Gorospe
Prostaglandin A2-mediated stabilization of p21 mRNA through an ERK-dependent pathway requiring the RNA-binding protein HuR.
The Journal of biological chemistry 2004;279(47):49298-306.
2004: Wengong Wang; Xiaoling Yang; Tomoko Kawai; Isabel López De Silanes; Krystyna Mazan-Mamczarz; Peili Chen; YuhMin Chook; Christina Quensel; Matthias Köhler; Myriam Gorospe
AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR.
The Journal of biological chemistry 2004;279(46):48376-88.
2004: Ashish Lal; Krystyna Mazan-Mamczarz; Tomoko Kawai; Xiaoling Yang; Jennifer L Martindale; Myriam Gorospe
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs.
The EMBO journal 2004;23(15):3092-102.
2004: Isabel López De Silanes; Ming Zhan; Ashish Lal; Xiaoling Yang; Myriam Gorospe
Identification of a target RNA motif for RNA-binding protein HuR.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):2987-92.
2003: Isabel López De Silanes; JINSHUI FAN; Xiaoling Yang; Alan B Zonderman; Olga Potapova; Ellen S Pizer; Myriam Gorospe
Role of the RNA-binding protein HuR in colon carcinogenesis.
Oncogene 2003;22(46):7146-54.
2003: Wengong Wang; Xiaoling Yang; Isabel López De Silanes; David Carling; Myriam Gorospe
Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function.
The Journal of biological chemistry 2003;278(29):27016-23.
2002: JINSHUI FAN; Xiaoling Yang; Wengong Wang; William H Wood; Kevin G Becker; Myriam Gorospe
Global analysis of stress-regulated mRNA turnover by using cDNA arrays.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10611-6.
2002: Wengong Wang; JINSHUI FAN; Xiaoling Yang; Stefanie Fürer-Galban; Isabel Lopez de Silanes; Cayetano von Kobbe; Jia Guo; Steve N Georas; Fabienne Foufelle; D Grahame Hardie; David Carling; Myriam Gorospe
AMP-activated kinase regulates cytoplasmic HuR.
Molecular and cellular biology 2002;22(10):3425-36.
2001: Wengong Wang; Xiaoling Yang; V J Cristofalo; Nikki J Holbrook; Myriam Gorospe
Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence.
Molecular and cellular biology 2001;21(17):5889-98.
2001: Peili Chen; Dorothy Hutter; Xiaoling Yang; Myriam Gorospe; R J Davis; Yusen Liu
Discordance between the binding affinity of mitogen-activated protein kinase subfamily members for MAP kinase phosphatase-2 and their ability to activate the phosphatase catalytically.
The Journal of biological chemistry 2001;276(31):29440-9.
2000: S Lin; Wengong Wang; Gerald M Wilson; Xiaoling Yang; Gary Brewer; Nikki J Holbrook; Myriam Gorospe
Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover.
Molecular and cellular biology 2000;20(21):7903-13.