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Zhen Yang

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Chao Che; Fangfang Li; Song Li; Shuo Lin; Shengchang Xin; Zhixiong Yu; Liyan Zhou; Zhen Yang
One-pot syntheses of isoquinolin-3-ones and benzo-1,4-diazepin-2,5-diones utilizing Ugi-4CR post-transformation strategy.
Guang Lin; Yongxiang Liu; Zheng Xiang; Le Chang; Jiahua Chen; Zhen Yang
Enantioselective total syntheses of (+)-gallocatechin, (-)-epigallocatechin, and 8-C-ascorbyl-(-)-epigallocatechin.
Shouliang Yang; Jiahua Chen; Lin Wang; Yumeng Xi; Rong Zhu; Zhen Yang
Asymmetric total syntheses of ansamacrolactams (+)-Q-1047H-A-A and (+)-Q-1047H-R-A.

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All Publications

2013: Chao Che; Fangfang Li; Song Li; Shuo Lin; Shengchang Xin; Zhixiong Yu; Liyan Zhou; Zhen Yang
One-pot syntheses of isoquinolin-3-ones and benzo-1,4-diazepin-2,5-diones utilizing Ugi-4CR post-transformation strategy.
ACS combinatorial science 2013;15(4):202-7.
2013: Guang Lin; Yongxiang Liu; Zheng Xiang; Le Chang; Jiahua Chen; Zhen Yang
Enantioselective total syntheses of (+)-gallocatechin, (-)-epigallocatechin, and 8-C-ascorbyl-(-)-epigallocatechin.
Chemistry, an Asian journal 2013;8(4):700-4.
2013: Shouliang Yang; Jiahua Chen; Lin Wang; Yumeng Xi; Rong Zhu; Zhen Yang
Asymmetric total syntheses of ansamacrolactams (+)-Q-1047H-A-A and (+)-Q-1047H-R-A.
Organic letters 2013;15(4):812-5.
2013: Hao Wei; Zhen Yang; Gang Liu; Chuang Qiao; Chuang-Chuang Li
Stereoselective total syntheses of (-)-flueggine A and (+)-virosaine B.
Angewandte Chemie (International ed. in English) 2013;52(2):620-4.
2013: Na Wu; Lujiang Deng; Chuangchuang Li; Lianzhu Liu; Qi Liu; Zhen Yang
Reverse regioselectivity in the palladium(II) thiourea catalyzed intermolecular Pauson-Khand reaction.
Chemistry, an Asian journal 2013;8(1):65-8.
2012: Qi Liu; Junmin Quan; Guoxin Wang; Na Wu; Chuang-Chuang Li; Yuanzhen Li; Guang Lin; Guozong Yue; Zhen Yang
Total synthesis of (±)-pentalenolactone A methyl ester.
Angewandte Chemie (International ed. in English) 2012;51(48):12072-6.
2012: Na Wu; Zhen Yang; Andrei S Batsanov; Antonios Messinis; Andrew Whiting; Todd B Marder
Palladium(II)-catalysed tandem cyclisation of electron-deficient aromatic enynes.
Chemical communications (Cambridge, England) 2012;48(80):9986-8.
2012: Rongfeng Lan; Guimiao Lin; Fei Lu; Jing Wang; Yanchao Wang; Jun Xu; Zhen Yang; Feng Yin; Yuan-Hua Ding; Jianxian Gong; Xiaoming Zhang; Hui Zhang
Dissecting the phenotypes of Plk1 inhibition in cancer cells using novel kinase inhibitory chemical CBB2001.
Laboratory investigation; a journal of technical methods and pathology 2012;92(10):1503-14.
2012: Wei-Wu Ren; Tian-Wen Sun; Ye-Feng Tang; Qing Xiao; Ling-Min Xu; Jia-Hua Chen; Zhi-Xing Chen; Yong Li; Fan-Ke Meng; Qin-Da Ye; Lin You; Zi-Yang Zhang; Ming-Zhe Zhao; Zhen Yang
Diastereoselective total synthesis of (±)-schindilactone a, Part 3: The final phase and completion.
Chemistry, an Asian journal 2012;7(10):2341-50.
2012: Yong Li; Fan-Ke Meng; Wei-Wu Ren; Tian-Wen Sun; Yue-Fan Wang; Qing Xiao; Ling-Min Xu; Jia-Hua Chen; Zhi-Xing Chen; Qin-Da Ye; Lin You; Zhen Yang
Diastereoselective total synthesis of (±)-schindilactone A, Part 2: Construction of the fully functionalized CDEFGH ring system.
Chemistry, an Asian journal 2012;7(10):2334-40.
2012: Tian-Wen Sun; Ye-Feng Tang; Qing Xiao; Ling-Min Xu; Jia-Hua Chen; Yong Li; Yi-Fan Liu; Fan-Ke Meng; Wei-Wu Ren; Yan-Dong Zhang; Ming-Zhe Zhao; Zhen Yang
Diastereoselective total synthesis of (±)-schindilactone A, Part 1: Construction of the ABC and FGH ring systems and initial attempts to construct the CDEF ring system.
Chemistry, an Asian journal 2012;7(10):2321-33.
2012: Yuefan Wang; Lingmin Xu; Jiahua Chen; Ruocheng Yu; Zhen Yang
CoBr2-TMTU-zinc catalysed-Pauson-Khand reaction.
Chemical communications (Cambridge, England) 2012;48(66):8183-5.
2012: Xianhua Wang; Yuefan Wang; Jiejia Xu; Zhen Yang; Wanrui Zhang; Xing Zhang; Ming Zheng; Yi Ding; Tingting Hou; Zhanglong Huang; Chongshu Jian; Meng Ouyang; Wei Shang; Heping Cheng
Superoxide flashes: elemental events of mitochondrial ROS signaling in the heart.
Journal of molecular and cellular cardiology 2012;52(5):940-8.
2012: Le Chang; Junkai Fu; Hao Jiang; Chuang-Chuang Li; Bin Liu; Zhen Yang
Synthesizing the tetracyclic core of nanolobatolide.
The Journal of organic chemistry 2012;77(7):3609-14.
2012: Jie Guo; Hong-Ping He; Ying Leng; Zhen Yang; Li-Yan Zhou; Xiao-Jiang Hao
Inhibition of 11b-HSD1 by tetracyclic triterpenoids from Euphorbia kansui.
Molecules (Basel, Switzerland) 2012;17(10):11826-38.
2012: Chao Che; Song Li; Shuo Lin; Taofeng Shao; Chuanye Tao; Shengchang Xin; Bo Yang; Zhixiong Yu; Zhen Yang
Synthesis and characterization of Sant-75 derivatives as Hedgehog-pathway inhibitors.
Beilstein journal of organic chemistry 2012;8():841-9.
2011: Hang Shi; Lili Shi; Ceheng Tan; Lichao Fang; Chuang-Chuang Li; Tuoping Luo; Weibin Zhang; Zhen Yang
Total syntheses of drimane-type sesquiterpenoids enabled by a gold-catalyzed tandem reaction.
Journal of the American Chemical Society 2011;133(38):14944-7.
2011: Qing Xiao; Ling-Min Xu; Qin-Da Ye; Lin You; Ming-Zhe Zhao; Jia-Hua Chen; Zhi-Xing Chen; Jian-Xian Gong; Yong Li; Yi-Fan Liu; Fan-Ke Meng; Wei-Wu Ren; Zhen-Hua Shan; Ying Shi; Tian-Wen Sun; Ye-Feng Tang; Zhen Yang
Diastereoselective total synthesis of (±)-schindilactone A.
Angewandte Chemie (International ed. in English) 2011;50(32):7373-7.
2011: Tao Xu; Chuang-Chuang Li; Zhen Yang
A concise approach for the total synthesis of pseudolaric acid A.
Organic letters 2011;13(10):2630-3.
2011: Lichao Fang; Yuan Chen; Jun Huang; Lianzhu Liu; Junmin Quan; Chuang-Chuang Li; Zhen Yang
Formal synthesis of cortistatins.
The Journal of organic chemistry 2011;76(8):2479-87.
2011: Lin Wang; Yumeng Xi; Shouliang Yang; Rong Zhu; Yufan Liang; Jiahua Chen; Zhen Yang
Asymmetric total synthesis and structural elucidation of NFAT-68.
Organic letters 2011;13(1):74-7.
2010: Ziyang Zhang; Jiahua Chen; Zhen Yang; Yefeng Tang
Rapid biomimetic total synthesis of (±)-rossinone B.
Organic letters 2010;12(23):5554-7.
2010: Jianxian Gong; Guang Lin; Wenbo Sun; Chuang-Chuang Li; Zhen Yang
Total synthesis of (±) maoecrystal V.
Journal of the American Chemical Society 2010;132(47):16745-6.
2010: Lian-Zhu Liu; Jin-Chun Han; Guo-Zong Yue; Chuang-Chuang Li; Zhen Yang
Asymmetric total synthesis of caribenol A.
Journal of the American Chemical Society 2010;132(39):13608-9.
2010: Haixia Zou; Liyan Zhou; Yuanzhen Li; Yi Cui; Hanbing Zhong; Zhengying Pan; Zhen Yang; Junmin Quan
Benzo[e]isoindole-1,3-diones as potential inhibitors of glycogen synthase kinase-3 (GSK-3). Synthesis, kinase inhibitory activity, zebrafish phenotype, and modeling of binding mode.
Journal of medicinal chemistry 2010;53(3):994-1003.
2010: Ling-Min Xu; Bi-Jie Li; Zhen Yang; Zhang-Jie Shi
Organopalladium(IV) chemistry.
Chemical Society reviews 2010;39(2):712-33.
2009: Yi Cui; Hao Jiang; Zhengtao Li; Na Wu; Zhen Yang; Junmin Quan
Unexpected regioselectivity in the synthesis of pyranonaphthoquinone via the Diels-Alder reaction.
Organic letters 2009;11(20):4628-31.
2009: Hongbo Yang; Jing Xiang; Nengdong Wang; Yun Zhao; Joel Hyman; Song Li; Jin Jiang; James Kenneth Chen; Zhen Yang; Shuo Lin
Converse conformational control of smoothened activity by structurally related small molecules.
The Journal of biological chemistry 2009;284(31):20876-84.
2009: Qing Xiao; Wen-Hua Wang; Gang Liu; Fan-Ke Meng; Jia-Hua Chen; Zhen Yang; Zhang-Jie Shi
Direct imidation to construct 1H-benzo[d]imidazole through Pd(II)-catalyzed C-H activation promoted by thiourea.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(30):7292-6.
2009: Yu Lan; Lujiang Deng; Jing Liu; Can Wang; Olaf Wiest; Zhen Yang; Yun-Dong Wu
On the mechanism of the palladium catalyzed intramolecular Pauson-Khand-type reaction.
The Journal of organic chemistry 2009;74(14):5049-58.
2009: Lin Wang; Jianxian Gong; Lujiang Deng; Zheng Xiang; Zhixing Chen; Yuefan Wang; Jiahua Chen; Zhen Yang
Formal total synthesis of N-methylmaysenine.
Organic letters 2009;11(8):1809-12.
2009: Jing Xiang; Hongbo Yang; Chao Che; Haixia Zou; Hanshuo Yang; Yuquan Wei; Junmin Quan; Hui Zhang; Zhen Yang; Shuo Lin
Identifying tumor cell growth inhibitors by combinatorial chemistry and zebrafish assays.
PloS one 2009;4(2):e4361.
2008: Yan-Dong Zhang; Wei-Wu Ren; Yu Lan; Qing Xiao; Kai Wang; Jie Xu; Jia-Hua Chen; Zhen Yang
Stereoselective construction of an unprecedented 7-8 fused ring system in micrandilactone a by [3,3]-sigmatropic rearrangement.
Organic letters 2008;10(4):665-8.
2007: Chao Che; Jing Xiang; Guo-Xin Wang; Reza Fathi; Jun-Min Quan; Zhen Yang
One-pot synthesis of quinoline-based tetracycles by a tandem three-component reaction.
Journal of combinatorial chemistry 2007;9(6):982-9.
2007: Yuanzhen Li; Haixia Zou; Jianxian Gong; Jing Xiang; Tuoping Luo; Jun-Min Quan; Guoxin Wang; Zhen Yang
Efficient synthesis of maleimides and carbazoles via Zn(OTf)(2)-catalyzed tandem annulations of isonitriles and allenic esters.
Organic letters 2007;9(20):4057-60.
2007: Yongxiang Liu; Kui Lu; Mingji Dai; Kai Wang; Wanqing Wu; Jiahua Chen; Junmin Quan; Zhen Yang
An efficient one-pot asymmetric synthesis of biaryl compounds via Diels-Alder/retro-Diels-Alder cascade reactions.
Organic letters 2007;9(5):805-8.
2006: Zhibo Ma; Zheng Xiang; Tuoping Luo; Kui Lu; Zhibin Xu; Jiahua Chen; Zhen Yang
Synthesis of functionalized quinolines via Ugi and Pd-catalyzed intramolecular arylation reactions.
Journal of combinatorial chemistry 2006;8(5):696-704.
2006: Chuang-Chuang Li; Cui-Hua Wang; Bo Liang; Xin-Hao Zhang; Lu-Jiang Deng; Shuang Liang; Jia-Hua Chen; Yun-Dong Wu; Zhen Yang
Synthetic study of 1,3-butadiene-based IMDA approach to construct a [5-7-6] tricyclic core and its application to the total synthesis of C8-epi-guanacastepene O.
The Journal of organic chemistry 2006;71(18):6892-7.
2006: Li-ying Pei; Zhan-cheng Gao; Zhen Yang; Dong-guang Wei; Shi-xin Wang; Jian-min Ji; Bao-guo Jiang
Investigation of the influencing factors on severe acute respiratory syndrome among health care workers.
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2006;38(3):271-5.
2006: Kui Lu; Mengwei Huang; Zheng Xiang; Yongxiang Liu; Jiahua Chen; Zhen Yang
Development of a concise and diversity-oriented approach for the synthesis of plecomacrolides via the diene-ene RCM.
Organic letters 2006;8(6):1193-6.
2006: Yan-Dong Zhang; Ye-Feng Tang; Tuo-Ping Luo; Juan Shen; Ji-Hua Chen; Zhen Yang
Application of RCM reaction in the construction of ABC ring of micrandilactone A.
Organic letters 2006;8(1):107-10.
2005: Kui Lu; Tuoping Luo; Zheng Xiang; Zejin You; Reza Fathi; Jiahua Chen; Zhen Yang
A concise and diversity-oriented strategy for the synthesis of benzofurans and indoles via Ugi and Diels-Alder reactions.
Journal of combinatorial chemistry 2005;7(6):958-67.
2005: Chuang-Chuang Li; Shuang Liang; Xin-Hao Zhang; Zhi-Xiang Xie; Jia-Hua Chen; Yun-Dong Wu; Zhen Yang
Exploring an expedient IMDA reaction approach to construct the guanacastepene core.
Organic letters 2005;7(17):3709-12.
2005: Bo Liang; Mengwei Huang; Zejin You; Zhengchang Xiong; Kui Lu; Reza Fathi; Jiahua Chen; Zhen Yang
Pd-catalyzed copper-free carbonylative Sonogashira reaction of aryl iodides with alkynes for the synthesis of alkynyl ketones and flavones by using water as a solvent.
The Journal of organic chemistry 2005;70(15):6097-100.
2005: Yefeng Tang; Lujiang Deng; Yangdong Zhang; Guangbin Dong; Jiahua Chen; Zhen Yang
Thioureas as ligands in the pd-catalyzed intramolecular Pauson-Khand reaction.
Organic letters 2005;7(8):1657-9.
2005: Yefeng Tang; Yandong Zhang; Mingji Dai; Tuoping Luo; Lujiang Deng; Jiahua Chen; Zhen Yang
A highly efficient synthesis of the FGH ring of micrandilactone A. Application of thioureas as ligands in the Co-catalyzed Pauson-Khand reaction and Pd-catalyzed carbonylative annulation.
Organic letters 2005;7(5):885-8.
2005: Yefeng Tang; Lujiang Deng; Yandong Zhang; Guangbin Dong; Jiahua Chen; Zhen Yang
Tetramethyl thiourea/Co2(CO)8-catalyzed Pauson-Khand reaction under balloon pressure of CO.
Organic letters 2005;7(4):593-5.
2005: Bo Liang; Mingji Dai; Jiahua Chen; Zhen Yang
Copper-free sonogashira coupling reaction with PdCl2 in water under aerobic conditions.
The Journal of organic chemistry 2005;70(1):391-3.
2004: Zhengchang Xiong; Nengdong Wang; Mingji Dai; Ang Li; Jiahua Chen; Zhen Yang
Synthesis of novel palladacycles and their application in Heck and Suzuki reactions under aerobic conditions.
Organic letters 2004;6(19):3337-40.
2004: Zheng Xiang; Tuoping Luo; Kui Lu; Jiayue Cui; Xiaomeng Shi; Reza Fathi; Jiahua Chen; Zhen Yang
Concise synthesis of isoquinoline via the Ugi and Heck reactions.
Organic letters 2004;6(18):3155-8.
2004: Mingji Dai; Bo Liang; Cuihua Wang; Jiahua Chen; Zhen Yang
Synthesis of a novel C2-symmetric thiourea and its application in the Pd-catalyzed cross-coupling reactions with arenediazonium salts under aerobic conditions.
Organic letters 2004;6(2):221-4.
2003: Chuang-Chuang Li; Zhi Xiang Xie; Yan Dong Zhang; Jia Hua Chen; Zhen Yang
Total synthesis of wedelolactone.
The Journal of organic chemistry 2003;68(22):8500-4.