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Stephen Yant

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Brian Moldt; Stephen R Yant; Peter Refsing Andersen; Mark A Kay; Jacob Giehm Mikkelsen
Cis-acting gene regulatory activities in the terminal regions of sleeping beauty DNA transposon-based vectors.
Brian S Garrison; Stephen R Yant; Jacob Giehm Mikkelsen; Mark A Kay
Postintegrative gene silencing within the Sleeping Beauty transposition system.
Hatem Zayed; Lily Xia; Anton Yerich; Stephen R Yant; Mark A Kay; M Puttaraju; Gerard J McGarrity; David L. Wiest; R Scott McIvor; Jakub Tolar; Bruce R Blazar
Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery.

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All Publications

2007: Brian Moldt; Stephen R Yant; Peter Refsing Andersen; Mark A Kay; Jacob Giehm Mikkelsen
Cis-acting gene regulatory activities in the terminal regions of sleeping beauty DNA transposon-based vectors.
Human gene therapy 2007;18(12):1193-204.
2007: Brian S Garrison; Stephen R Yant; Jacob Giehm Mikkelsen; Mark A Kay
Postintegrative gene silencing within the Sleeping Beauty transposition system.
Molecular and cellular biology 2007;27(24):8824-33.
2007: Hatem Zayed; Lily Xia; Anton Yerich; Stephen R Yant; Mark A Kay; M Puttaraju; Gerard J McGarrity; David L. Wiest; R Scott McIvor; Jakub Tolar; Bruce R Blazar
Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(7):1273-9.
2007: Bassel Akache; Dirk Grimm; Xuan Shen; Sally Fuess; Stephen R Yant; Dariya S Glazer; Julie Park; Mark A Kay
A two-hybrid screen identifies cathepsins B and L as uncoating factors for adeno-associated virus 2 and 8.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(2):330-9.
2007: Jakub Tolar; Alma J Nauta; Mark J Osborn; Angela Panoskaltsis-Mortari; Ron T McElmurry; Scott Bell; Lily Xia; Ning Zhou; Megan Riddle; Tania M Schroeder; Jennifer J Westendorf; R Scott McIvor; Pancras Hogendoorn; Karoly Szuhai; Leann Oseth; Betsy Hirsch; Stephen R Yant; Mark A Kay; Alexandra Peister; Darwin J Prockop; Willem E Fibbe; Bruce R Blazar
Sarcoma derived from cultured mesenchymal stem cells.
Stem cells (Dayton, Ohio) 2007;25(2):371-9.
2007: Stephen R Yant; Yong Huang; Bassel Akache; Mark A Kay
Site-directed transposon integration in human cells.
Nucleic acids research 2007;35(7):e50.
2007: Anja Ehrhardt; Stephen R Yant; Jeffery C Giering; Hui Xu; Jeffrey A Engler; Mark A Kay
Somatic integration from an adenoviral hybrid vector into a hot spot in mouse liver results in persistent transgene expression levels in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(1):146-56.
2006: Bassel Akache; Dirk Grimm; Kusum Pandey; Stephen R Yant; Hui Xu; Mark A Kay
The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9.
Journal of virology 2006;80(19):9831-6.
2006: Jakub Tolar; Matthew J O'Shaughnessy; Angela Panoskaltsis-Mortari; Ron T McElmurry; Scott Bell; Megan Riddle; R Scott McIvor; Stephen R Yant; Mark A Kay; Diane Krause; Catherine M Verfaillie; Bruce R Blazar
Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells.
Blood 2006;107(10):4182-8.
2005: Jakub Tolar; Mark J Osborn; Scott Bell; Ron T McElmurry; Lily Xia; Megan Riddle; Angela Panoskaltsis-Mortari; Yuehua Jiang; R Scott McIvor; Christopher H Contag; Stephen R Yant; Mark A Kay; Catherine M Verfaillie; Bruce R Blazar
Real-time in vivo imaging of stem cells following transgenesis by transposition.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(1):42-8.
2005: Stephen R Yant; Xiaolin Wu; Yong Huang; Brian Garrison; Shawn M Burgess; Mark A Kay
High-resolution genome-wide mapping of transposon integration in mammals.
Molecular and cellular biology 2005;25(6):2085-94.
2004: Stephen R Yant; Julie Park; Yong Huang; Jacob Giehm Mikkelsen; Mark A Kay
Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells.
Molecular and cellular biology 2004;24(20):9239-47.
2003: Stephen R Yant; Mark A Kay
Nonhomologous-end-joining factors regulate DNA repair fidelity during Sleeping Beauty element transposition in mammalian cells.
Molecular and cellular biology 2003;23(23):8505-18.
2003: Jacob Giehm Mikkelsen; Stephen R Yant; Leonard Meuse; Zan Huang; Hui Xu; Mark A Kay
Helper-Independent Sleeping Beauty transposon-transposase vectors for efficient nonviral gene delivery and persistent gene expression in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(4):654-65.
2003: Susana Ortiz-Urda; Qun Lin; Stephen R Yant; Douglas R Keene; Mark A Kay; Paul A Khavari
Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer.
Gene therapy 2003;10(13):1099-104.
2002: Eugenio Montini; Patrice K Held; Meenakshi Noll; Nicolas Morcinek; Muhsen Al-Dhalimy; Milton Finegold; Stephen R Yant; Mark A Kay; Markus Grompe
In vivo correction of murine tyrosinemia type I by DNA-mediated transposition.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(6):759-69.
2002: Stephen R Yant; Anja Ehrhardt; Jacob Giehm Mikkelsen; Leonard Meuse; Thao Pham; Mark A Kay
Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo.
Nature biotechnology 2002;20(10):999-1005.
2001: Hiroyuki Nakai; Stephen R Yant; Theresa A Storm; Sally Fuess; Leonard Meuse; Mark A Kay
Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo.
Journal of virology 2001;75(15):6969-76.
2001: Zhi-Ying Chen; Stephen R Yant; Cheng-Yi He; Leonard Meuse; S Shen; Mark A Kay
Linear DNAs concatemerize in vivo and result in sustained transgene expression in mouse liver.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(3):403-10.
2000: Stephen R Yant; Leonard Meuse; W Chiu; Z Ivics; Z Izsvak; Mark A Kay
Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system.
Nature genetics 2000;25(1):35-41.