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Hiroshi Yao

Research Profile

Living Beings

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Kenji Fukuda; Takefumi Yuzuriha; Naoko Kinukawa; Ryo Murakawa; Yuki Takashima; Akira Uchino; Setsuro Ibayashi; Mitsuo Iida; Hiroshi Yao; Makoto Hirano
Alcohol intake and quantitative MRI findings among community dwelling Japanese subjects.
Takahiro Ohmine; Yoshikazu Miwa; Hiroshi Yao; Takefumi Yuzuriha; Yuki Takashima; Akira Uchino; Fumi Takahashi-Yanaga; Sachio Morimoto; Yoshihiko Maehara; Toshiyuki Sasaguri
Association between arterial stiffness and cerebral white matter lesions in community-dwelling elderly subjects.
Tsuneaki Sadanaga; Fumiko Sadanaga; Hiroshi Yao; Masatoshi Fujishima
An evaluation of ECG leads used to assess QT prolongation.

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2009: Kenji Fukuda; Takefumi Yuzuriha; Naoko Kinukawa; Ryo Murakawa; Yuki Takashima; Akira Uchino; Setsuro Ibayashi; Mitsuo Iida; Hiroshi Yao; Makoto Hirano
Alcohol intake and quantitative MRI findings among community dwelling Japanese subjects.
Journal of the neurological sciences 2009;278(1-2):30-4.
2008: Takahiro Ohmine; Yoshikazu Miwa; Hiroshi Yao; Takefumi Yuzuriha; Yuki Takashima; Akira Uchino; Fumi Takahashi-Yanaga; Sachio Morimoto; Yoshihiko Maehara; Toshiyuki Sasaguri
Association between arterial stiffness and cerebral white matter lesions in community-dwelling elderly subjects.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(1):75-81.
2006: Tsuneaki Sadanaga; Fumiko Sadanaga; Hiroshi Yao; Masatoshi Fujishima
An evaluation of ECG leads used to assess QT prolongation.
Cardiology 2006;105(3):149-54.
2004: Hiroshi Yao; Fumiko Sadanaga-Akiyoshi; Setsuro Ibayashi; Mitsuo Iida
Nicotinamide attenuates focal ischemic brain injury: meta-analysis or mechanism of protection.
Stroke; a journal of cerebral circulation 2004;35(12):2757-8; author reply 2758-9.
2004: Tsuneaki Sadanaga; Fumiko Sadanaga; Hiroshi Yao; Masatoshi Fujishima
Abnormal QT prolongation and psychotropic drug therapy in psychiatric patients: significance of bradycardia-dependent QT prolongation.
Journal of electrocardiology 2004;37(4):267-73.
2004: Tsuneaki Sadanaga; Fumiko Sadanaga; Hiroshi Yao; Masatoshi Fujishima
Heart rate dependent modification of the QTc cut-off values can improve accurate evaluation of QT prolongation.
The American journal of cardiology 2004;93(6):772-5.
2003: Hiroshi Yao; Hiroshi Sugimori; Kenji Fukuda; Junichi Takada; Hiroaki Ooboshi; Takanari Kitazono; Setsuro Ibayashi; Mitsuo Iida
Photothrombotic middle cerebral artery occlusion and reperfusion laser system in spontaneously hypertensive rats.
Stroke; a journal of cerebral circulation 2003;34(11):2716-21.
2003: Yuki Takashima; Hiroshi Yao; Hiroshi Koga; Koichi Endo; Takashi Matsumoto; Akira Uchino; Fumiko Sadanaga-Akiyoshi; Takefumi Yuzuriha; Yasuo Kuroda
Frontal lobe dysfunction caused by multiple lacunar infarction in community-dwelling elderly subjects.
Journal of the neurological sciences 2003;214(1-2):37-41.
2003: Fumiko Sadanaga-Akiyoshi; Hiroshi Yao; Sei-ichi Tanuma; Tatsuo Nakahara; Jong Soon Hong; Setsuro Ibayashi; Hideyuki Uchimura; Masatoshi Fujishima
Nicotinamide attenuates focal ischemic brain injury in rats: with special reference to changes in nicotinamide and NAD+ levels in ischemic core and penumbra.
Neurochemical research 2003;28(8):1227-34.
2003: Junichi Takada; Hiroaki Ooboshi; Hiroshi Yao; Takanari Kitazono; Setsuro Ibayashi; Mitsuo Iida
Adenovirus-mediated gene transfer to ischemic brain is augmented in aged rats.
Experimental gerontology 2003;38(4):423-9.
2002: Hiroshi Yao; Yasushi Okada; Setsuro Ibayashi
Therapeutic time window for YAG laser-induced reperfusion of thrombotic stroke in hypertensive rats.
Neuroreport 2002;13(8):1005-8.
2002: Hirofumi Koga; Takefumi Yuzuriha; Hiroshi Yao; K Endo; Shigeto Hiejima; Y Takashima; F Sadanaga; Toshio Matsumoto; A Uchino; Koji Ogomori; Atsushi Ichimiya; H Uchimura; N Tashiro
Quantitative MRI findings and cognitive impairment among community dwelling elderly subjects.
Journal of neurology, neurosurgery, and psychiatry 2002;72(6):737-41.
2001: Jiro Kitayama; Takanari Kitazono; Hiroshi Yao; Hiroaki Ooboshi; H Takaba; Tetsuro Ago; Masatoshi Fujishima; Setsuro Ibayashi
Inhibition of Na+/H+ exchanger reduces infarct volume of focal cerebral ischemia in rats.
Brain research 2001;922(2):223-8.
2001: Hiroshi Yao; Ryoko Takasawa; Kenji Fukuda; Daisuke Shiokawa; Fumiko Sadanaga-Akiyoshi; Setsuro Ibayashi; Sei-ichi Tanuma; Hideyuki Uchimura
DNA fragmentation in ischemic core and penumbra in focal cerebral ischemia in rats.
Brain research. Molecular brain research 2001;91(1-2):112-8.
2001: Hiroaki Ooboshi; Setsuro Ibayashi; Junichi Takada; Hiroshi Yao; Takanari Kitazono; Masatoshi Fujishima
Adenovirus-mediated gene transfer to ischemic brain: ischemic flow threshold for transgene expression.
Stroke; a journal of cerebral circulation 2001;32(4):1043-7.
2001: Hiroshi Yao; Setsuro Ibayashi; Fumiko Sadanaga-Akiyoshi; Kenji Fukuda; Junichi Takada; Hiroaki Ooboshi; Takanari Kitazono; Hideyuki Uchimura; Masatoshi Fujishima
[YAG laser-induced reperfusion of photothrombotic middle cerebral artery occlusion in rats].
Nō to shinkei = Brain and nerve 2001;53(3):253-7.
2000: Masatoshi Fujishima; Hiroshi Yao; A Terashi; K Tagawa; M Matsumoto; H Hara; I Akiguchi; K Suzuki; K Nishimaru; F Udaka; T Gyoten; J Takeuchi; R Hamada; Y Yoshida; Setsuro Ibayashi
Deep white matter lesions on MRI, and not silent brain infarcts are related to headache and dizziness of non-specific cause in non-stroke Japanese subjects.
Internal medicine (Tokyo, Japan) 2000;39(9):727-31.
2000: Kenji Fukuda; Hiroshi Yao; Setsuro Ibayashi; T Nakahara; Hideyuki Uchimura; Masatoshi Fujishima; E D Hall
Ovariectomy exacerbates and estrogen replacement attenuates photothrombotic focal ischemic brain injury in rats.
Stroke; a journal of cerebral circulation 2000;31(1):155-60.
1999: Tatsuo Nakahara; Toshihide Kuroki; Hisao Hondo; T Tsutsumi; Kenji Fukuda; Hiroshi Yao; Hideyuki Uchimura
Effects of atypical antipsychotic drugs vs. haloperidol on expression of heat shock protein in the discrete brain regions of phencyclidine-treated rats.
Brain research. Molecular brain research 1999;73(1-2):193-7.
1999: H Goda; Hiroshi Yao; Hiroshi Nakane; K Fukuda; Tatsuo Nakahara; Setsuro Ibayashi; Hideyuki Uchimura; Masatoshi Fujishima
Cerebral blood flow threshold and regional heterogeneity of heat shock protein 72 induction following transient forebrain ischemia in rats.
Neurochemical research 1999;24(5):679-83.
1999: Hiroshi Yao; Takefumi Yuzuriha; Hirofumi Koga; K Fukuda; K Endo; Toshio Matsumoto; A Kato; A Uchino; T Ezaki; Setsuro Ibayashi; H Uchimura; Masatoshi Fujishima
Decreased plasma tryptophan associated with deep white matter lesions in elderly subjects.
Journal of neurology, neurosurgery, and psychiatry 1999;66(1):100-3.
1998: H Cai; Hiroshi Yao; Setsuro Ibayashi; Hideyuki Uchimura; Masatoshi Fujishima
Photothrombotic middle cerebral artery occlusion in spontaneously hypertensive rats: influence of substrain, gender, and distal middle cerebral artery patterns on infarct size.
Stroke; a journal of cerebral circulation 1998;29(9):1982-6; discussion 1986-7.
1998: Hiroshi Nakane; Hiroshi Yao; Setsuro Ibayashi; Takanari Kitazono; Hiroaki Ooboshi; Hideyuki Uchimura; Masatoshi Fujishima
Protein kinase C modulates ischemia-induced amino acids release in the striatum of hypertensive rats.
Brain research 1998;782(1-2):290-6.
1997: H Takaba; Taku Nagao; Hiroshi Yao; Takanari Kitazono; Setsuro Ibayashi; Masatoshi Fujishima
An ATP-sensitive potassium channel activator reduces infarct volume in focal cerebral ischemia in rats.
The American journal of physiology 1997;273(2 Pt 2):R583-6.
1997: Hiroshi Yao; Setsuro Ibayashi; Hiroshi Nakane; H Cai; Hideyuki Uchimura; Masatoshi Fujishima
AMPA receptor antagonist, YM90K, reduces infarct volume in thrombotic distal middle cerebral artery occlusion in spontaneously hypertensive rats.
Brain research 1997;753(1):80-5.
1997: Hiroshi Nakane; Tatsuo Nakahara; Hiroshi Yao; Hiroaki Ooboshi; Setsuro Ibayashi; Hideyuki Uchimura; Masatoshi Fujishima
Age-related changes in the DNA and RNA content of the brain in spontaneously hypertensive rats.
Neurochemical research 1997;22(3):253-6.
1996: H Cai; Hiroshi Yao; Setsuro Ibayashi; H Takaba; Masatoshi Fujishima
Amlodipine, a Ca2+ channel antagonist, modifies cerebral blood flow autoregulation in hypertensive rats.
European journal of pharmacology 1996;313(1-2):103-6.
1996: Hiroshi Yao; Setsuro Ibayashi; H Sugimori; Koji Fujii; Masatoshi Fujishima
Simplified model of krypton laser-induced thrombotic distal middle cerebral artery occlusion in spontaneously hypertensive rats.
Stroke; a journal of cerebral circulation 1996;27(2):333-6.
1995: H Cai; Setsuro Ibayashi; Hiroshi Yao; H Sugimori; Seizo Sadoshima; Masatoshi Fujishima
The alpha 1-adrenoceptor antagonist, doxazosin, modulates the lower limit of autoregulation of cerebral blood flow during hemorrhagic hypotension in anesthetized hypertensive rats.
European journal of pharmacology 1995;286(3):249-53.
1995: Hiroshi Nakane; Hiroaki Ooboshi; Setsuro Ibayashi; Hiroshi Yao; Seizo Sadoshima; Masatoshi Fujishima
Isradipine, a calcium channel blocker, attenuates the ischemia-induced release of dopamine but not glutamate in rats.
Neuroscience letters 1995;188(3):151-4.
1995: Hiroaki Ooboshi; Seizo Sadoshima; Hiroshi Yao; Setsuro Ibayashi; T Matsumoto; Hideyuki Uchimura; Masatoshi Fujishima
Ischemia-induced release of amino acids in the hippocampus of aged hypertensive rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1995;15(2):227-34.
1993: Hiroshi Yao; Hiroaki Ooboshi; Setsuro Ibayashi; Hideyuki Uchimura; Masatoshi Fujishima
Cerebral blood flow and ischemia-induced neurotransmitter release in the striatum of aged spontaneously hypertensive rats.
Stroke; a journal of cerebral circulation 1993;24(4):577-80.
1993: Hiroaki Ooboshi; Seizo Sadoshima; Setsuro Ibayashi; Hiroshi Yao; Hideyuki Uchimura; Masatoshi Fujishima
Isradipine attenuates the ischemia-induced release of dopamine in the striatum of the rat.
European journal of pharmacology 1993;233(1):165-8.
1993: Hiroshi Yao; Taku Nagao; Hiroaki Ooboshi; T Matsumoto; M Hirano; Tatsuo Nakahara; Seizo Sadoshima; Hideyuki Uchimura; Masatoshi Fujishima
Ischemia-induced changes in brain monoamine metabolism in aged spontaneously hypertensive rats.
Gerontology 1993;39(3):128-35.
1992: Hiroshi Yao; Seizo Sadoshima; Setsuro Ibayashi; Yasuo Kuwabara; Y Ichiya; Masatoshi Fujishima
Leukoaraiosis and dementia in hypertensive patients.
Stroke; a journal of cerebral circulation 1992;23(11):1673-7.
1992: Hideki Hirakata; Hiroshi Yao; S Osato; Setsuro Ibayashi; K Onoyama; M Otsuka; Y Ichiya; Y Kuwabara; Y Masuda; Masatoshi Fujishima
CBF and oxygen metabolism in hemodialysis patients: effects of anemia correction with recombinant human EPO.
The American journal of physiology 1992;262(5 Pt 2):F737-43.
1992: Hiroaki Ooboshi; Seizo Sadoshima; Hiroshi Yao; Tatsuo Nakahara; Hideyuki Uchimura; Masatoshi Fujishima
Inhibition of ischemia-induced dopamine release by omega-conotoxin, a calcium channel blocker, in the striatum of spontaneously hypertensive rats: in vivo brain dialysis study.
Journal of neurochemistry 1992;58(1):298-303.
1991: Hiroshi Yao; Seizo Sadoshima; Hiroaki Ooboshi; Y Sato; Hideyuki Uchimura; Masatoshi Fujishima
Age-related vulnerability to cerebral ischemia in spontaneously hypertensive rats.
Stroke; a journal of cerebral circulation 1991;22(11):1414-8.
1991: A Nagashima; Hiroshi Yao; Y Okada; Seizo Sadoshima; Y Takada; Masatoshi Fujishima
[A case of metoclopramide-induced neuroleptic malignant syndrome with cerebrospinal fluid lactic acidosis].
Nō to shinkei = Brain and nerve 1991;43(4):387-92.
1990: Hiroshi Yao; Seizo Sadoshima; Yasuo Kuwabara; Y Ichiya; Masatoshi Fujishima
Cerebral blood flow and oxygen metabolism in patients with vascular dementia of the Binswanger type.
Stroke; a journal of cerebral circulation 1990;21(12):1694-9.
1990: Hiroshi Yao
[Monoamine contents and norepinephrine turnover in brain stem nuclei of young and adult spontaneously hypertensive and Wistar-Kyoto rats].
Fukuoka igaku zasshi = Hukuoka acta medica 1990;81(11):370-83.
1990: Tatsuo Nakahara; M Hirano; T Matsumoto; Toshihide Kuroki; Y Tatebayashi; T Tsutsumi; K Nishiyama; Hiroaki Ooboshi; K Nakamura; Hiroshi Yao
Regional distribution of DNA and RNA in rat brain: a sensitive determination using high-performance liquid chromatography with electrochemical detection.
Neurochemical research 1990;15(6):609-11.
1990: Hiroshi Yao; Hiroaki Ooboshi; Seizo Sadoshima; K Takano; Setsuro Ibayashi; Masatoshi Fujishima
Ischemic flow threshold for striatal dopamine release in rats.
Neurochemical research 1990;15(5):547-9.
1990: Hiroshi Yao; T Matsumoto; M Hirano; Hideyuki Uchimura; Hiroaki Ooboshi; Seizo Sadoshima; Masatoshi Fujishima
Striatal glutamic acid and gamma-aminobutyric acid in transient cerebral ischemia in spontaneously hypertensive rats.
Japanese heart journal 1990;31(3):385-92.
1990: Hiroaki Ooboshi; Seizo Sadoshima; Koji Fujii; Hiroshi Yao; Setsuro Ibayashi; Masatoshi Fujishima
Acute effects of antihypertensive agents on cerebral blood flow in hypertensive rats.
European journal of pharmacology 1990;179(3):253-61.
1990: Koji Fujii; Seizo Sadoshima; Y Okada; Hiroshi Yao; Yasuo Kuwabara; Y Ichiya; Masatoshi Fujishima
Cerebral blood flow and metabolism in normotensive and hypertensive patients with transient neurologic deficits.
Stroke; a journal of cerebral circulation 1990;21(2):283-90.
1989: Seizo Sadoshima; Hiroaki Ooboshi; Y Okada; Hiroshi Yao; T Ishitsuka; Masatoshi Fujishima
Effect of thromboxane synthetase inhibitor on cerebral circulation and metabolism during experimental cerebral ischemia in spontaneously hypertensive rats.
European journal of pharmacology 1989;169(1):75-83.
1989: Hiroshi Yao; Seizo Sadoshima; Y Nishimura; Koji Fujii; M Oshima; T Ishitsuka; Masatoshi Fujishima
Cerebrospinal fluid lactate in patients with diabetes mellitus and hypoglycaemic coma.
Journal of neurology, neurosurgery, and psychiatry 1989;52(3):372-5.
1989: Koji Fujii; Seizo Sadoshima; Hiroshi Yao; F Yoshida; Masanori Iwase; Masatoshi Fujishima
Cerebral ischemia in spontaneously hypertensive rats with type 2 (noninsulin-dependent) diabetes mellitus, cerebral blood flow and tissue metabolism.
Gerontology 1989;35(2-3):78-87.
1988: Hiroshi Yao; Seizo Sadoshima; T Ishitsuka; Taku Nagao; Masatoshi Fujishima; T Tsutsumi; Hideyuki Uchimura
Massive striatal dopamine release in acute cerebral ischemia in rats.
Experientia 1988;44(6):506-8.
1988: O Shiokawa; Seizo Sadoshima; Koji Fujii; Hiroshi Yao; Masatoshi Fujishima
Impairment of cerebellar blood flow autoregulation during cerebral ischemia in spontaneously hypertensive rats.
Stroke; a journal of cerebral circulation 1988;19(5):615-22.
1987: Seizo Sadoshima; Koji Fujii; K Kusuda; O Shiokawa; Hiroshi Yao; Setsuro Ibayashi; Masatoshi Fujishima
Importance of bilateral sympathetic innervation on cerebral blood flow autoregulation in the thalamus.
Brain research 1987;413(2):297-301.
1987: Hiroshi Yao; Seizo Sadoshima; Koji Fujii; K Kusuda; T Ishitsuka; K Tamaki; Masatoshi Fujishima
Cerebrospinal fluid lactate in patients with hepatic encephalopathy.
European neurology 1987;27(3):182-7.