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Alpha Yap

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TOP 3
Magdalene Michael; Alpha S Yap
The regulation and functional impact of actin assembly at cadherin cell-cell adhesions.
Siew-Ping Han; Alpha S Yap
An α-catenin déjà vu.
William M Brieher; Alpha S Yap
Cadherin junctions and their cytoskeleton(s).

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All Publications

2013: Magdalene Michael; Alpha S Yap
The regulation and functional impact of actin assembly at cadherin cell-cell adhesions.
Seminars in cell & developmental biology 2013;24(4):298-307.
2013: Siew-Ping Han; Alpha S Yap
An α-catenin déjà vu.
Nature cell biology 2013;15(3):238-9.
2013: William M Brieher; Alpha S Yap
Cadherin junctions and their cytoskeleton(s).
Current opinion in cell biology 2013;25(1):39-46.
2013: Aparna Ratheesh; Rashmi Priya; Alpha S Yap
Coordinating Rho and Rac: the regulation of Rho GTPase signaling and cadherin junctions.
Progress in molecular biology and translational science 2013;116():49-68.
2012: Suzie Verma; Zhe Yang; Radiya Ali; Guillermo A Gomez; Siew Ping Han; Eva M Kovacs; Magdalene Michael; Aparna Ratheesh; Rohan D Teasdale; Alpha S Yap
A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens.
Molecular biology of the cell 2012;23(23):4601-10.
2012: Aparna Ratheesh; Alpha S Yap
A bigger picture: classical cadherins and the dynamic actin cytoskeleton.
Nature reviews. Molecular cell biology 2012;13(10):673-9.
2012: Andrea I McClatchey; Alpha S Yap
Contact inhibition (of proliferation) redux.
Current opinion in cell biology 2012;24(5):685-94.
2012: Aparna Ratheesh; Samantha J Stehbens; Suzie Verma; Anna Akhmanova; Nicholas H Brown; Guillermo A Gomez; Kai Jiang; Eva M Kovacs; Rashmi Priya; Alpha S Yap
Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens.
Nature cell biology 2012;14(8):818-28.
2012: Siew Ping Han; Alpha S Yap
The cytoskeleton and classical cadherin adhesions.
Sub-cellular biochemistry 2012;60():111-35.
2011: Guillermo A Gomez; Robert W McLachlan; Alpha S Yap
Productive tension: force-sensing and homeostasis of cell-cell junctions.
Trends in cell biology 2011;21(9):499-505.
2011: Eva M Kovacs; Steven G Thomas; Suzie Verma; Alpha S Yap
Tuba and N-WASP function cooperatively to position the central lumen during epithelial cyst morphogenesis.
Cell adhesion & migration 2011;5(4):344-50.
2011: Carien M Niessen; Deborah Leckband; Alpha S Yap
Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation.
Physiological reviews 2011;91(2):691-731.
2011: Sabine Mangold; Selwin K Wu; Suzanne J Norwood; Brett M Collins; Nicholas A Hamilton; Peter Thorn; Alpha S Yap
Hepatocyte growth factor acutely perturbs actin filament anchorage at the epithelial zonula adherens.
Current biology : CB 2011;21(6):503-7.
2011: Michael Smutny; Selwin K Wu; Alpha S Yap; Guillermo A Gomez; Sabine Mangold; Nicholas A Hamilton
Multicomponent analysis of junctional movements regulated by myosin II isoforms at the epithelial zonula adherens.
PloS one 2011;6(7):e22458.
2011: Robert W McLachlan; Alpha S Yap
Protein tyrosine phosphatase activity is necessary for E-cadherin-activated Src signaling.
Cytoskeleton (Hoboken, N.J.) 2011;68(1):32-43.
2010: Michael Smutny; Hayley L Cox; Joanne M Leerberg; Eva M Kovacs; Mary Anne Conti; Charles Ferguson; Nicholas A Hamilton; Robert G Parton; Robert S Adelstein; Alpha S Yap
Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens.
Nature cell biology 2010;12(7):696-702.
2010: Michael Smutny; Alpha S Yap
Neighborly relations: cadherins and mechanotransduction.
The Journal of cell biology 2010;189(7):1075-7.
2010: Jennifer A Zallen; Alpha S Yap
Morphogenesis in Kyoto: a confluence of cell and developmental biology.
Molecular biology of the cell 2010;21(6):845-7.
2010: Jack T H Wang; Markus C Kerr; Seetha Karunaratne; Angela Jeanes; Alpha S Yap; Rohan Teasdale
The SNX-PX-BAR family in macropinocytosis: the regulation of macropinosome formation by SNX-PX-BAR proteins.
PloS one 2010;5(10):e13763.
2010: Aparna Ratheesh; Alpha S Yap
Doing cell biology in embryos: regulated membrane traffic and its implications for cadherin biology.
F1000 biology reports 2010;2():.
2009: Angela Jeanes; Michael Smutny; Joanne M Leerberg; Alpha S Yap
Phosphatidylinositol 3'-kinase signalling supports cell height in established epithelial monolayers.
Journal of molecular histology 2009;40(5-6):395-405.
2009: Gang Ren; Matthew S Crampton; Alpha S Yap
Cortactin: Coordinating adhesion and the actin cytoskeleton at cellular protrusions.
Cell motility and the cytoskeleton 2009;66(10):865-73.
2009: Nicole R den Elzen; Carmen V Buttery; Madhavi P Maddugoda; Gang Ren; Alpha S Yap
Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia.
Molecular biology of the cell 2009;20(16):3740-50.
2009: Gang Ren; Falak M Helwani; Suzie Verma; Robert W McLachlan; Scott A Weed; Alpha S Yap
Cortactin is a functional target of E-cadherin-activated Src family kinases in MCF7 epithelial monolayers.
The Journal of biological chemistry 2009;284(28):18913-22.
2009: Anna Akhmanova; Samantha J Stehbens; Alpha S Yap
Touch, grasp, deliver and control: functional cross-talk between microtubules and cell adhesions.
Traffic (Copenhagen, Denmark) 2009;10(3):268-74.
2009: Samantha J Stehbens; Anna Akhmanova; Alpha S Yap
Microtubules and cadherins: a neglected partnership.
Frontiers in bioscience : a journal and virtual library 2009;14():3159-67.
2008: Anna Akhmanova; Alpha S Yap
Organizing junctions at the cell-cell interface.
Cell 2008;135(5):791-3.
2008: Eva M Kovacs; Alpha S Yap
Cell-cell contact: cooperating clusters of actin and cadherin.
Current biology : CB 2008;18(15):R667-R669.
2008: Natasha Webb; Geoff Connolly; Ross Tellam; Alpha S Yap; Rajiv Khanna
Epstein-Barr virus associated modulation of Wnt pathway is not dependent on latent membrane protein-1.
PloS one 2008;3(9):e3254.
2007: Alpha S Yap; Matthew S Crampton; Jeff Hardin
Making and breaking contacts: the cellular biology of cadherin regulation.
Current opinion in cell biology 2007;19(5):508-14.
2007: Robert W McLachlan; Astrid Kraemer; Falak M Helwani; Eva M Kovacs; Alpha S Yap
E-cadherin adhesion activates c-Src signaling at cell-cell contacts.
Molecular biology of the cell 2007;18(8):3214-23.
2007: Madhavi P Maddugoda; Matthew S Crampton; Annette M Shewan; Alpha S Yap
Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cells.
The Journal of cell biology 2007;178(3):529-40.
2007: Robert W McLachlan; Alpha S Yap
Not so simple: the complexity of phosphotyrosine signaling at cadherin adhesive contacts.
Journal of molecular medicine (Berlin, Germany) 2007;85(6):545-54.
2007: Astrid Kraemer; Marita Goodwin; Suzie Verma; Alpha S Yap; Radiya Ali
Rac is a dominant regulator of cadherin-directed actin assembly that is activated by adhesive ligation independently of Tiam1.
American journal of physiology. Cell physiology 2007;292(3):C1061-9.
2006: Carien M Niessen; Alpha S Yap
Another job for the talented p120-catenin.
Cell 2006;127(5):875-7.
2006: Jeanie A Scott; Alpha S Yap
Cinderella no longer: alpha-catenin steps out of cadherin's shadow.
Journal of cell science 2006;119(Pt 22):4599-605.
2006: Samantha J Stehbens; Andrew D Paterson; Matthew S Crampton; Annette M Shewan; Charles Ferguson; Anna Akhmanova; Robert Parton; Alpha S Yap
Dynamic microtubules regulate the local concentration of E-cadherin at cell-cell contacts.
Journal of cell science 2006;119(Pt 9):1801-11.
2006: Xin Zhang; B Starling Emerald; Svetlana Mukhina; Kumarasamypet M Mohankumar; Astrid Kraemer; Alpha S Yap; Peter D Gluckman; Kok-Onn Lee; Peter E Lobie
HOXA1 is required for E-cadherin-dependent anchorage-independent survival of human mammary carcinoma cells.
The Journal of biological chemistry 2006;281(10):6471-81.
2006: Jeanie A Scott; Annette M Shewan; Nicole R den Elzen; Joseph Loureiro; Frank B Gertler; Alpha S Yap
Ena/VASP proteins can regulate distinct modes of actin organization at cadherin-adhesive contacts.
Molecular biology of the cell 2006;17(3):1085-95.
2005: Vania M M Braga; Alpha S Yap
The challenges of abundance: epithelial junctions and small GTPase signalling.
Current opinion in cell biology 2005;17(5):466-74.
2005: Annette M Shewan; Madhavi Maddugoda; Astrid Kraemer; Samantha J Stehbens; Suzie Verma; Eva M Kovacs; Alpha S Yap
Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contacts.
Molecular biology of the cell 2005;16(10):4531-42.
2005: Cara J Gottardi; Nicole R den Elzen; Alpha S Yap
When domestiques rebel: kinesins, cadherins and neuronal proliferation.
Nature cell biology 2005;7(5):445-7.
2005: Jian-Hong Pang; Astrid Kraemer; Samantha J Stehbens; Margaret C Frame; Alpha S Yap
Recruitment of phosphoinositide 3-kinase defines a positive contribution of tyrosine kinase signaling to E-cadherin function.
The Journal of biological chemistry 2005;280(4):3043-50.
2004: Marita Goodwin; Alpha S Yap
Classical cadherin adhesion molecules: coordinating cell adhesion, signaling and the cytoskeleton.
Journal of molecular histology 2004;35(8-9):839-44.
2004: Suzie Verma; Annette M Shewan; Jeanie A Scott; Falak M Helwani; Nicole R den Elzen; Hiroaki Miki; Tadaomi Takenawa; Alpha S Yap
Arp2/3 activity is necessary for efficient formation of E-cadherin adhesive contacts.
The Journal of biological chemistry 2004;279(32):34062-70.
2004: Falak M Helwani; Eva M Kovacs; Andrew D Paterson; Suzie Verma; Radiya Ali; Alan S Fanning; Scott A Weed; Alpha S Yap
Cortactin is necessary for E-cadherin-mediated contact formation and actin reorganization.
The Journal of cell biology 2004;164(6):899-910.
2003: Mark Peifer; Alpha S Yap
Traffic control: p120-catenin acts as a gatekeeper to control the fate of classical cadherins in mammalian cells.
The Journal of cell biology 2003;163(3):437-40.
2003: Kevin C Miranda; Shannon R Joseph; Alpha S Yap; Rohan Teasdale; Jennifer L Stow
Contextual binding of p120ctn to E-cadherin at the basolateral plasma membrane in polarized epithelia.
The Journal of biological chemistry 2003;278(44):43480-8.
2003: Marita Goodwin; Eva M Kovacs; Molly A Thoreson; Albert B Reynolds; Alpha S Yap
Minimal mutation of the cytoplasmic tail inhibits the ability of E-cadherin to activate Rac but not phosphatidylinositol 3-kinase: direct evidence of a role for cadherin-activated Rac signaling in adhesion and contact formation.
The Journal of biological chemistry 2003;278(23):20533-9.
2003: Andrew D Paterson; Robert Parton; Charles Ferguson; Jennifer L Stow; Alpha S Yap
Characterization of E-cadherin endocytosis in isolated MCF-7 and chinese hamster ovary cells: the initial fate of unbound E-cadherin.
The Journal of biological chemistry 2003;278(23):21050-7.
2003: Astrid Kraemer; Alpha S Yap
Coupling adhesion to actin bundles in the inner ear. Novel functions for novel cadherins.
EMBO reports 2003;4(3):244-5.
2003: Alpha S Yap; Eva M Kovacs
Direct cadherin-activated cell signaling: a view from the plasma membrane.
The Journal of cell biology 2003;160(1):11-6.
2002: Eva M Kovacs; Alpha S Yap
The web and the rock: cell adhesion and the ARP2/3 complex.
Developmental cell 2002;3(6):760-1.
2002: Tam Luan Le; Shannon R Joseph; Alpha S Yap; Jennifer L Stow
Protein kinase C regulates endocytosis and recycling of E-cadherin.
American journal of physiology. Cell physiology 2002;283(2):C489-99.
2002: Eva M Kovacs; Marita Goodwin; Radiya Ali; Andrew D Paterson; Alpha S Yap
Cadherin-directed actin assembly: E-cadherin physically associates with the Arp2/3 complex to direct actin assembly in nascent adhesive contacts.
Current biology : CB 2002;12(5):379-82.
2002: Eva M Kovacs; Radiya Ali; Ailsa J McCormack; Alpha S Yap
E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts.
The Journal of biological chemistry 2002;277(8):6708-18.
2002: Oliver Jarrett; Jennifer L Stow; Alpha S Yap; Brian Key
Dynamin-dependent endocytosis is necessary for convergent-extension movements in Xenopus animal cap explants.
The International journal of developmental biology 2002;46(4):467-73.
2001: K C Miranda; Tatiana Khromykh; P Christy; Tam Luan Le; Cara J Gottardi; Alpha S Yap; Jennifer L Stow; Rohan Teasdale
A dileucine motif targets E-cadherin to the basolateral cell surface in Madin-Darby canine kidney and LLC-PK1 epithelial cells.
The Journal of biological chemistry 2001;276(25):22565-72.
2001: Alpha S Yap
Initiation of cell locomotility is a morphogenetic checkpoint in thyroid epithelial cells regulated by ERK and PI3-kinase signals.
Cell motility and the cytoskeleton 2001;49(2):93-103.
2001: Alpha S Yap; SW Manley
Microtubule integrity is essential for apical polarization and epithelial morphogenesis in the thyroid.
Cell motility and the cytoskeleton 2001;48(3):201-12.
1999: Tam Luan Le; Alpha S Yap; Jennifer L Stow
Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics.
The Journal of cell biology 1999;146(1):219-32.
1998: Alpha S Yap; James M Mullin; BR Stevenson
Molecular analyses of tight junction physiology: insights and paradoxes.
The Journal of membrane biology 1998;163(3):159-67.
1998: Alpha S Yap; Carien M Niessen; Barry M Gumbiner
The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn.
The Journal of cell biology 1998;141(3):779-89.
1998: Alpha S Yap
The morphogenetic role of cadherin cell adhesion molecules in human cancer: a thematic review.
Cancer investigation 1998;16(4):252-61.
1997: Alpha S Yap; BR Stevenson; V Cooper; SW Manley
Protein tyrosine phosphorylation influences adhesive junction assembly and follicular organization of cultured thyroid epithelial cells.
Endocrinology 1997;138(6):2315-24.
1997: Alpha S Yap; WM Brieher; M Pruschy; Barry M Gumbiner
Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function.
Current biology : CB 1997;7(5):308-15.
1997: Alpha S Yap; WM Brieher; Barry M Gumbiner
Molecular and functional analysis of cadherin-based adherens junctions.
Annual review of cell and developmental biology 1997;13():119-46.
1996: W M Brieher; Alpha S Yap; Barry M Gumbiner
Lateral dimerization is required for the homophilic binding activity of C-cadherin.
The Journal of cell biology 1996;135(2):487-96.
1995: Alpha S Yap; B R Stevenson; J R Keast; SW Manley
Cadherin-mediated adhesion and apical membrane assembly define distinct steps during thyroid epithelial polarization and lumen formation.
Endocrinology 1995;136(10):4672-80.
1995: Alpha S Yap; B R Stevenson; K C Abel; E J Cragoe; SW Manley
Microtubule integrity is necessary for the epithelial barrier function of cultured thyroid cell monolayers.
Experimental cell research 1995;218(2):540-50.
1995: Alpha S Yap; B R Stevenson; M J Waters; J R Keast; SW Manley
Vinculin localization and actin stress fibers differ in thyroid cells organized as monolayers or follicles.
Cell motility and the cytoskeleton 1995;32(4):318-31.
1994: Alpha S Yap; SW Manley
Thyrotropin inhibits the intrinsic locomotility of thyroid cells organized as follicles in primary culture.
Experimental cell research 1994;214(1):408-17.
1994: Alpha S Yap; B R Stevenson; J W Armstrong; J R Keast; SW Manley
Thyroid epithelial morphogenesis in vitro: a role for bumetanide-sensitive Cl- secretion during follicular lumen development.
Experimental cell research 1994;213(2):319-26.
1994: Alpha S Yap; J R Keast; SW Manley
Thyroid cell spreading and focal adhesion formation depend upon protein tyrosine phosphorylation and actin microfilaments.
Experimental cell research 1994;210(2):306-14.
1993: Alpha S Yap; SW Manley
Contact inhibition of cell spreading: a mechanism for the maintenance of thyroid cell aggregation in vitro.
Experimental cell research 1993;208(1):121-7.
1993: Alpha S Yap; J W Armstrong; E J Cragoe; J R Bourke; G J Huxham; SW Manley
Activation of sodium transport mediates regulation of thyroid follicle volume in response to hypotonic media.
The American journal of physiology 1993;264(4 Pt 1):E644-9.
1992: Alpha S Yap; K C Abel; J R Bourke; SW Manley
Differential regulation of thyroid cell-cell and cell-substrate adhesion by thyrotropin.
Experimental cell research 1992;202(2):366-9.
1991: Alpha S Yap; J W Armstrong; E J Cragoe; J R Bourke; G J Huxham; SW Manley
Regulation of thyroid follicular volume by bidirectional transepithelial ion transport.
Molecular and cellular endocrinology 1991;82(1):R1-5.