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Umit Yasar

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Aurel C Allabi; Jean-Claude Alvarez; André Bigot; yves horsmans; Roger K Verbeeck; Umit Yasar; Jean-Luc Gala
Acenocoumarol sensitivity and pharmacokinetic characterization of CYP2C9 *5/*8,*8/*11,*9/*11 and VKORC1*2 in black African healthy Beninese subjects.
Ersin Gumus; Ozgur Karaca; Nuray Uslu; Melih O Babaoglu; Necati Balamtekin; Gökhan Baysoy; Atilla Bozkurt; Hulya Demir; Aysel Yuce; Umit Yasar
Evaluation of lansoprazole as a probe for assessing cytochrome P450 2C19 activity and genotype-phenotype correlation in childhood.
Umit Yasar; Melih O Babaoglu; Atila Bozkurt
Disposition of a CYP2C9 phenotyping agent, losartan, is not influenced by the common 3435C > T variation of the drug transporter gene ABCB1 (MDR1).

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2012: Aurel C Allabi; Jean-Claude Alvarez; André Bigot; yves horsmans; Roger K Verbeeck; Umit Yasar; Jean-Luc Gala
Acenocoumarol sensitivity and pharmacokinetic characterization of CYP2C9 *5/*8,*8/*11,*9/*11 and VKORC1*2 in black African healthy Beninese subjects.
European journal of drug metabolism and pharmacokinetics 2012;37(2):125-32.
2012: Ersin Gumus; Ozgur Karaca; Nuray Uslu; Melih O Babaoglu; Necati Balamtekin; Gökhan Baysoy; Atilla Bozkurt; Hulya Demir; Aysel Yuce; Umit Yasar
Evaluation of lansoprazole as a probe for assessing cytochrome P450 2C19 activity and genotype-phenotype correlation in childhood.
European journal of clinical pharmacology 2012;68(5):629-36.
2008: Umit Yasar; Melih O Babaoglu; Atila Bozkurt
Disposition of a CYP2C9 phenotyping agent, losartan, is not influenced by the common 3435C > T variation of the drug transporter gene ABCB1 (MDR1).
Basic & clinical pharmacology & toxicology 2008;103(2):176-9.
2008: Ugur Unluturk; Ayla Harmanci; Melih Babaoglu; Umit Yasar; Kubilay Varli; Murat Bastepe; Miyase Bayraktar
Molecular diagnosis and clinical characterization of pseudohypoparathyroidism type-Ib in a patient with mild Albright's hereditary osteodystrophy-like features, epileptic seizures, and defective renal handling of uric acid.
The American journal of the medical sciences 2008;336(1):84-90.
2008: Nese Dericioglu; Melih O Babaoglu; Umit Yasar; I Burak Bal; Atila Bozkurt; Serap Saygi
Multidrug resistance in patients undergoing resective epilepsy surgery is not associated with C3435T polymorphism in the ABCB1 (MDR1) gene.
Epilepsy research 2008;80(1):42-6.
2007: Salih Gulsen; Servet Inci; Sinan Yuruk; Umit Yasar; Tuncalp Ozgen
Effect of raloxifene on cerebral vasospasm following experimental subarachnoid hemorrhage in rats.
Neurologia medico-chirurgica 2007;47(12):537-42; discussion 542.
2007: Abdurrahman Tufan; Melih O Babaoglu; Ali Akdogan; Umit Yasar; Meral Calguneri; Umut Kalyoncu; Omer Karadag; Mutlu Hayran; A Ihsan Ertenli; Atila Bozkurt; Sedat Kiraz
Association of drug transporter gene ABCB1 (MDR1) 3435C to T polymorphism with colchicine response in familial Mediterranean fever.
The Journal of rheumatology 2007;34(7):1540-4.
2007: Arzu Gunes; Erhan Bilir; Hakan Zengil; Melih O Babaoglu; Atila Bozkurt; Umit Yasar
Inhibitory effect of valproic acid on cytochrome P450 2C9 activity in epilepsy patients.
Basic & clinical pharmacology & toxicology 2007;100(6):383-6.
2007: Sule Unal; Benan Bayrakci; Umit Yasar; Tevfik Karagoz
Successful treatment of propafenone, digoxin and warfarin overdosage with plasma exchange therapy and rifampicin.
Clinical drug investigation 2007;27(7):505-8.
2007: Tamer Elkiran; H Harputluoglu; Umit Yasar; Melih O Babaoglu; A K Dincel; Kadri Altundag; Yavuz Ozisik; Nilufer Guler; Atila Bozkurt
Differential alteration of drug-metabolizing enzyme activities after cyclophosphamide/adriamycin administration in breast cancer patients.
Methods and findings in experimental and clinical pharmacology 2007;29(1):27-32.
2006: M C Boruban; Umit Yasar; Melih O Babaoglu; Orhan Sencan; Atila Bozkurt
Tamoxifen inhibits cytochrome P450 2C9 activity in breast cancer patients.
Journal of chemotherapy (Florence, Italy) 2006;18(4):421-4.
2006: Selim Kortunay; Umit Yasar; T Isik; Atila Bozkurt; Melih O Babaoglu
Variant alleles and genotypes of alcohol dehydrogenase 3 in a Turkish population.
Methods and findings in experimental and clinical pharmacology 2006;28(4):229-31.
2006: Arzu Gunes; Ugur Coskun; Cem Boruban; Nazan Gunel; Melih O Babaoglu; Orhan Sencan; Atila Bozkurt; Anders Rane; Moustapha Hassan; Hakan Zengil; Umit Yasar
Inhibitory effect of 5-fluorouracil on cytochrome P450 2C9 activity in cancer patients.
Basic & clinical pharmacology & toxicology 2006;98(2):197-200.
2006: Mevlut Kurt; Melih O Babaoglu; Umit Yasar; Ali Shorbagi; Nilufer Guler
Capecitabine-induced severe hypertriglyceridemia: report of two cases.
The Annals of pharmacotherapy 2006;40(2):328-31.
2006: Hanjing Xie; Laimonas Griskevicius; Lars Ståhle; Zuzana Hassan; Umit Yasar; Anders Rane; Ulrika Broberg; Eva Kimby; Moustapha Hassan
Pharmacogenetics of cyclophosphamide in patients with hematological malignancies.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;27(1):54-61.
2005: Umit Yasar; Anita Annas; Jan-Olof Svensson; Lucia Lazorova; P Artursson; Ayman Al-Shurbaji
Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein.
Xenobiotica; the fate of foreign compounds in biological systems 2005;35(8):785-96.
2005: H Xie; Parvaneh Afsharian; Ylva Terelius; Rajaa A Mirghani; Umit Yasar; A-L Hagbjörk; Stefan Lundgren; Y Hu; Anders Rane; Moustapha Hassan
Cyclophosphamide induces mRNA, protein and enzyme activity of cytochrome P450 in rat.
Xenobiotica; the fate of foreign compounds in biological systems 2005;35(3):239-51.
2004: Mike Ufer; Bernd Kammerer; Rainer Kahlich; Julia Kirchheiner; Umit Yasar; Jürgen Brockmöller; Anders Rane
Genetic polymorphisms of cytochrome P450 2C9 causing reduced phenprocoumon (S)-7-hydroxylation in vitro and in vivo.
Xenobiotica; the fate of foreign compounds in biological systems 2004;34(9):847-59.
2004: Aurel C Allabi; Jean-Luc Gala; yves horsmans; Melih O Babaoglu; Atila Bozkurt; Michel Heusterspreute; Umit Yasar
Functional impact of CYP2C95, CYP2C96, CYP2C98, and CYP2C911 in vivo among black Africans.
Clinical pharmacology and therapeutics 2004;76(2):113-8.
2004: Melih O Babaoglu; Omer Karadag; Yutaka Saikawa; Kadri Altundag; Tamer Elkiran; Umit Yasar; Atila Bozkurt
Hepatotoxicity due to a possible interaction between cytosine arabinoside and dipyridamole: a case report.
European journal of clinical pharmacology 2004;60(6):455-6.
2004: Melih O Babaoglu; Umit Yasar; Mia Sandberg; Erik Eliasson; Marja-Liisa Dahl; S Oguz Kayaalp; Atila Bozkurt
CYP2C9 genetic variants and losartan oxidation in a Turkish population.
European journal of clinical pharmacology 2004;60(5):337-42.
2004: Nese Dericioglu; Melih O Babaoglu; Serap Saygi; Atila Bozkurt; Umit Yasar
Warfarin resistance with poor CYP2C9 activity and CYP2C9*1*2 genotype.
The Annals of pharmacotherapy 2004;38(5):899.
2004: Omer Karadag; Melih O Babaoglu; Kadri Altundag; Tamer Elkiran; Umit Yasar; Atila Bozkurt
5-Fluorouracil-induced coronary spasm: may inhibition of hyperpolarization factors produced by CYP2C enzymes be the cause?
Oncology 2004;66(6):510-1.
2003: Umit Yasar; Anna M Bennet; Erik Eliasson; Stefan Lundgren; Björn Wiman; Ulf de Faire; Anders Rane
Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction.
Pharmacogenetics 2003;13(12):715-20.
2003: Kari Laine; Umit Yasar; Jolanta Widén; Gunnel Tybring
A screening study on the liability of eight different female sex steroids to inhibit CYP2C9, 2C19 and 3A4 activities in human liver microsomes.
Pharmacology & toxicology 2003;93(2):77-81.
2003: Pedro Dorado; Roland Berecz; Maria-Jesús Norberto; Umit Yasar; Marja-Liisa Dahl; Adrián LLerena
CYP2C9 genotypes and diclofenac metabolism in Spanish healthy volunteers.
European journal of clinical pharmacology 2003;59(3):221-5.
2003: Laimonas Griskevicius; Umit Yasar; Mia Sandberg; Mats Hidestrand; Erik Eliasson; Gunnel Tybring; Moustapha Hassan; Marja-Liisa Dahl
Bioactivation of cyclophosphamide: the role of polymorphic CYP2C enzymes.
European journal of clinical pharmacology 2003;59(2):103-9.
2003: Han-Jing Xie; Umit Yasar; Stefan Lundgren; Laimonas Griskevicius; Ylva Terelius; Moustapha Hassan; Anders Rane
Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation.
The pharmacogenomics journal 2003;3(1):53-61.
2002: Rajaa A Mirghani; Umit Yasar; Tao Zheng; James M Cook; Lars ´Gustafsson; Gunnel Tybring; Orjan Ericsson
Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(12):1368-71.
2002: Umit Yasar; Stefan Lundgren; Erik Eliasson; Anna Bennet; Björn Wiman; Ulf de Faire; Anders Rane
Linkage between the CYP2C8 and CYP2C9 genetic polymorphisms.
Biochemical and biophysical research communications 2002;299(1):25-8.
2002: Umit Yasar; Eleni Aklillu; Roberto Canaparo; Mia Sandberg; Jane Sayi; Hyung-Keun Roh; Agneta Wennerholm
Analysis of CYP2C9*5 in Caucasian, Oriental and black-African populations.
European journal of clinical pharmacology 2002;58(8):555-8.
2002: Mia Sandberg; Umit Yasar; Patrik Strömberg; Jan-Olov Höög; Erik Eliasson
Oxidation of celecoxib by polymorphic cytochrome P450 2C9 and alcohol dehydrogenase.
British journal of clinical pharmacology 2002;54(4):423-9.
2002: Umit Yasar; Marja-Liisa Dahl; Magnus Christensen; Erik Eliasson
Intra-individual variability in urinary losartan oxidation ratio, an in vivo marker of CYP2C9 activity.
British journal of clinical pharmacology 2002;54(2):183-5.
2002: Han-Jing Xie; Umit Yasar; Mia Sandberg; Anders Rane
Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity.
Journal of clinical pharmacy and therapeutics 2002;27(3):229-30.
2002: Umit Yasar; Erik Eliasson; Marja-Liisa Dahl
Association of CYP2C9 genotypes leading to high enzyme activity and colorectal cancer risk.
Carcinogenesis 2002;23(4):665; author reply 667-8.
2002: Umit Yasar; Cecilia Forslund-Bergengren; Gunnel Tybring; Pedro Dorado; Adrián LLerena; Folke Sjöqvist; Erik Eliasson; Marja-Liisa Dahl
Pharmacokinetics of losartan and its metabolite E-3174 in relation to the CYP2C9 genotype.
Clinical pharmacology and therapeutics 2002;71(1):89-98.
2001: Umit Yasar; Erik Eliasson; C Forslund-Bergengren; Gunnel Tybring; M Gadd; Folke Sjöqvist; Marja-Liisa Dahl
The role of CYP2C9 genotype in the metabolism of diclofenac in vivo and in vitro.
European journal of clinical pharmacology 2001;57(10):729-35.
2001: Maria Gabriella Scordo; Eleni Aklillu; Umit Yasar; Marja-Liisa Dahl; Edoardo Spina; Magnus Ingelman-Sundberg
Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population.
British journal of clinical pharmacology 2001;52(4):447-50.
2001: Umit Yasar; Mikael Oscarson; Erik Eliasson; Folke Sjöqvist
Mutations of the CYP2C9 gene and the response to warfarin.
Surgery 2001;129(3):384.
1999: Osman Cekiç; Cosar Batman; Yüksel Totan; Umit Yasar; Nursabah E Basci; Atila Bozkurt; S Oguz Kayaalp; Orhan Zilelioglu
Aqueous humour levels of topically applied ciprofloxacin and ofloxacin in the same subjects.
Eye (London, England) 1999;13 ( Pt 5)():656-9.
1999: Osman Cekiç; Cosar Batman; Umit Yasar; Yüksel Totan; Nursabah E Basci; Atila Bozkurt; Orhan Zilelioglu; S Oguz Kayaalp
Penetration of topical, oral, and combined administered ofloxacin into the subretinal fluid.
The British journal of ophthalmology 1999;83(10):1183-5.
1999: Osman Cekiç; Cosar Batman; Umit Yasar; N E Başci; Atila Bozkurt; S Oguz Kayaalp
Human aqueous and vitreous humour levels of ciprofloxacin following oral and topical administration.
Eye (London, England) 1999;13 ( Pt 4)():555-8.
1999: Osman Cekiç; Cosar Batman; Yüksel Totan; Umit Yasar; Nursabah E Basci; Atila Bozkurt; S Oguz Kayaalp
Penetration of ofloxacin and ciprofloxacin in aqueous humor after topical administration.
Ophthalmic surgery and lasers 1999;30(6):465-8.
1999: Umit Yasar; Sevim Erdem; Meral Tuncer
Cyclosporine A preparations and their vehicles induce contraction of the guinea pig gallbladder in vitro: the role of cyclooxygenase metabolites.
Pharmacology 1999;58(6):309-18.
1999: Umit Yasar; Erik Eliasson; Marja-Liisa Dahl; I Johansson; Magnus Ingelman-Sundberg; Folke Sjöqvist
Validation of methods for CYP2C9 genotyping: frequencies of mutant alleles in a Swedish population.
Biochemical and biophysical research communications 1999;254(3):628-31.
1998: Osman Cekiç; Cosar Batman; Umit Yasar; Nursabah E Basci; Atila Bozkurt; S Oguz Kayaalp
Comparison of aqueous humour and vitreous humour levels of two 0.3% ciprofloxacin eyedrops.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 1998;33(7):373-6.
1998: O Cekic; Cosar Batman; Umit Yasar; Nursabah E Basci; Atila Bozkurt; S Oguz Kayaalp
Penetration of ofloxacin in human aqueous and vitreous humors following oral and topical administration.
Retina (Philadelphia, Pa.) 1998;18(6):521-5.