FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Hiroshi Yasui

Research Profile

Disorders

Multiple Myeloma

Chemicals & Drugs

Anatomy

Physiology

Living Beings

SCID Mouse

Co-author Network

Publications

TOP 3
Paola Neri; Pierfrancesco Tassone; Masood Ahmad Shammas; Hiroshi Yasui; Ernestina Schipani; Ramesh Babu Batchu; Simona Blotta; Rao H Prabhala; Laurence Catley; Makoto Hamasaki; Teru Hideshima; Dharminder Chauhan; Gary S Jacob; Donald Picker; Salvatore Venuta; Kenneth C Anderson; Nikhil C Munshi
Biological pathways and in vivo antitumor activity induced by Atiprimod in myeloma.
Sonia Vallet; Noopur Raje; Kenji Ishitsuka; Teru Hideshima; klaus podar; Shweta Chhetri; Samantha Pozzi; Iris Breitkreutz; Tanyel Kiziltepe; Hiroshi Yasui; Enrique M Ocio; Norihiko Shiraishi; Janice Jin; Yutaka Okawa; Hiroshi Ikeda; Siddhartha Mukherjee; Nileshwari Vaghela; Diana Cirstea; marco ladetto; Mario Boccadoro; Kenneth C Anderson
MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts.
Teru Hideshima; Laurence Catley; Noopur Raje; Dharminder Chauhan; klaus podar; Constantine S Mitsiades; Yu-Tzu Tai; Sonia Vallet; Tanyel Kiziltepe; Enrique M Ocio; Hiroshi Ikeda; Yutaka Okawa; Hiromasa Hideshima; Nikhil C Munshi; Hiroshi Yasui; Paul G Richardson; Kenneth C Anderson
Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Hiroshi Yasui (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2007: Paola Neri; Pierfrancesco Tassone; Masood Ahmad Shammas; Hiroshi Yasui; Ernestina Schipani; Ramesh Babu Batchu; Simona Blotta; Rao H Prabhala; Laurence Catley; Makoto Hamasaki; Teru Hideshima; Dharminder Chauhan; Gary S Jacob; Donald Picker; Salvatore Venuta; Kenneth C Anderson; Nikhil C Munshi
Biological pathways and in vivo antitumor activity induced by Atiprimod in myeloma.
Leukemia 2007;21(12):2519-26.
2007: Sonia Vallet; Noopur Raje; Kenji Ishitsuka; Teru Hideshima; klaus podar; Shweta Chhetri; Samantha Pozzi; Iris Breitkreutz; Tanyel Kiziltepe; Hiroshi Yasui; Enrique M Ocio; Norihiko Shiraishi; Janice Jin; Yutaka Okawa; Hiroshi Ikeda; Siddhartha Mukherjee; Nileshwari Vaghela; Diana Cirstea; marco ladetto; Mario Boccadoro; Kenneth C Anderson
MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts.
Blood 2007;110(10):3744-52.
2007: Teru Hideshima; Laurence Catley; Noopur Raje; Dharminder Chauhan; klaus podar; Constantine S Mitsiades; Yu-Tzu Tai; Sonia Vallet; Tanyel Kiziltepe; Enrique M Ocio; Hiroshi Ikeda; Yutaka Okawa; Hiromasa Hideshima; Nikhil C Munshi; Hiroshi Yasui; Paul G Richardson; Kenneth C Anderson
Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells.
British journal of haematology 2007;138(6):783-91.
2007: Tanyel Kiziltepe; Teru Hideshima; Kenji Ishitsuka; Enrique M Ocio; Noopur Raje; Laurence Catley; Chun-Qi Li; Laura J Trudel; Hiroshi Yasui; Sonia Vallet; Jeffery L Kutok; Dharminder Chauhan; Constantine S Mitsiades; Joseph E Saavedra; Gerald N Wogan; Larry K Keefer; Paul J Shami; Kenneth C Anderson
JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells.
Blood 2007;110(2):709-18.
2007: Tanyel Kiziltepe; Teru Hideshima; Laurence Catley; Noopur Raje; Hiroshi Yasui; Norihiko Shiraishi; Yutaka Okawa; Hiroshi Ikeda; Sonia Vallet; Samantha Pozzi; Kenji Ishitsuka; Enrique M Ocio; Dharminder Chauhan; Kenneth C Anderson
5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells.
Molecular cancer therapeutics 2007;6(6):1718-27.
2007: Kumar Sukhdeo; Mala Mani; Yunyu Zhang; Jui Dutta; Hiroshi Yasui; Melissa D Rooney; Daniel E Carrasco; Mei Zheng; Haiying He; Yu-Tzu Tai; Constantine S Mitsiades; Kenneth C Anderson; Daniel R Carrasco
Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7516-21.
2007: Hiroshi Yasui; Teru Hideshima; H Ikeda; Enrique M Ocio; Tanyel Kiziltepe; Sonia Vallet; Y Okawa; Paola Neri; Kumar Sukhdeo; klaus podar; Dharminder Chauhan; Paul G Richardson; Noopur Raje; Daniel R Carrasco; Kenneth C Anderson
Novel etodolac analog SDX-308 (CEP-18082) induces cytotoxicity in multiple myeloma cells associated with inhibition of beta-catenin/TCF pathway.
Leukemia 2007;21(3):535-40.
2007: klaus podar; Marc S Raab; Giovanni Tonon; Martin Sattler; Daniela Barilà; Jing Zhang; Yu-Tzu Tai; Hiroshi Yasui; Noopur Raje; Ronald A DePinho; Teru Hideshima; Dharminder Chauhan; Kenneth C Anderson
Up-regulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma.
Cancer research 2007;67(4):1680-8.
2007: Hiroshi Yasui; Teru Hideshima; Hiroshi Ikeda; Janice Jin; Enrique M Ocio; Tanyel Kiziltepe; Yutaka Okawa; Sonia Vallet; klaus podar; Kenji Ishitsuka; Paul G Richardson; Christopher A Pargellis; Neil Moss; Noopur Raje; Kenneth C Anderson
BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth.
British journal of haematology 2007;136(3):414-23.
2006: klaus podar; Giovanni Tonon; Martin Sattler; Yu-Tzu Tai; Steven Legouill; Hiroshi Yasui; Kenji Ishitsuka; Shaji Kumar; Rakesh Kumar; Lini Pandite; Teru Hideshima; Dharminder Chauhan; Kenneth C Anderson
The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(51):19478-83.
2006: Hiroshi Yasui; Teru Hideshima; Kenneth C Anderson
Non-steroidal anti-inflammatory drug therapy for chronic lymphocytic leukemia.
Leukemia & lymphoma 2006;47(12):2445-6.
2006: Hiroshi Yasui; Teru Hideshima; Paul G Richardson; Kenneth C Anderson
Recent advances in the treatment of Multiple Myeloma.
Current pharmaceutical biotechnology 2006;7(5):381-93.
2006: Teru Hideshima; Paola Neri; Pierfrancesco Tassone; Hiroshi Yasui; Kenji Ishitsuka; Noopur Raje; Dharminder Chauhan; klaus podar; Constantine S Mitsiades; Lenny Dang; Nikhil C Munshi; Paul Richardson; David P Schenkein; Kenneth C Anderson
MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(19):5887-94.
2006: Noopur Raje; Shaji Kumar; Teru Hideshima; Kenji Ishitsuka; Hiroshi Yasui; Shweta Chhetri; Sonia Vallet; E Vonescu; Norihiko Shiraishi; Tanyel Kiziltepe; H L Elford; Nikhil C Munshi; Kenneth C Anderson
Didox, a ribonucleotide reductase inhibitor, induces apoptosis and inhibits DNA repair in multiple myeloma cells.
British journal of haematology 2006;135(1):52-61.
2006: Hiroshi Yasui; Teru Hideshima
[Proteasome inhibitor bortezomib as an anticancer drug].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2006;51(10 Suppl):1251-6.
2006: Paola Neri; Hiroshi Yasui; Teru Hideshima; Pierfrancesco Tassone; Noopur Raje; Laurence Catley; Catley P Laurence; Kenji Ishitsuka; Simona Blotta; Tanyel Kiziltepe; Enrique M Ocio; Mariateresa Fulciniti; Sarath Kanekal; Gary T Elliott; Nikhil C Munshi; Kenneth C Anderson
In vivo and in vitro cytotoxicity of R-etodolac with dexamethasone in glucocorticoid-resistant multiple myeloma cells.
British journal of haematology 2006;134(1):37-44.
2006: Teru Hideshima; Laurence Catley; Hiroshi Yasui; Kenji Ishitsuka; Noopur Raje; Constantine S Mitsiades; klaus podar; Nikhil C Munshi; Dharminder Chauhan; Paul G Richardson; Kenneth C Anderson
Perifosine, an oral bioactive novel alkylphospholipid, inhibits Akt and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells.
Blood 2006;107(10):4053-62.
2006: Hiroshi Yasui; Teru Hideshima; Paul G Richardson; Kenneth C Anderson
Novel therapeutic strategies targeting growth factor signalling cascades in multiple myeloma.
British journal of haematology 2006;132(4):385-97.
2006: Aldo Roccaro; Teru Hideshima; Noopur Raje; Shaji Kumar; Kenji Ishitsuka; Hiroshi Yasui; Norihiko Shiraishi; Dragana Vukasovic; Beatrice Nico; Angelo Vacca; Franco Dammacco; Paul G Richardson; Kenneth C Anderson
Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells.
Cancer research 2006;66(1):184-91.
2005: Kenji Ishitsuka; Teru Hideshima; Makoto Hamasaki; Noopur Raje; Shaji Kumar; klaus podar; Steven Le Gouill; Norihiko Shiraishi; Hiroshi Yasui; Aldo Roccaro; Yu-Zu Tai; Dharminder Chauhan; Robert Fram; Kazuo Tamura; Jugnu Jain; Kenneth C Anderson
Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway.
Oncogene 2005;24(38):5888-96.
2005: Kenji Ishitsuka; Teru Hideshima; Makoto Hamasaki; Noopur Raje; Shaji Kumar; Hiromasa Hideshima; Norihiko Shiraishi; Hiroshi Yasui; Aldo Roccaro; Paul Richardson; klaus podar; Steven Le Gouill; Dharminder Chauhan; Kazuo Tamura; Jack Arbiser; Kenneth C Anderson
Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis.
Blood 2005;106(5):1794-800.
2005: Hiroshi Yasui; Teru Hideshima; Noopur Raje; Aldo Roccaro; Norihiko Shiraishi; Shaji Kumar; Makoto Hamasaki; Kenji Ishitsuka; Yu-Tzu Tai; klaus podar; Laurence Catley; Constantine S Mitsiades; Paul G Richardson; Rainer Albert; Volker Brinkmann; Dharminder Chauhan; Kenneth C Anderson
FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance.
Cancer research 2005;65(16):7478-84.
2005: Noopur Raje; Shaji Kumar; Teru Hideshima; Aldo Roccaro; Kenji Ishitsuka; Hiroshi Yasui; Norihiko Shiraishi; Dharminder Chauhan; Nikhil C Munshi; Simon R Green; Kenneth C Anderson
Seliciclib (CYC202 or R-roscovitine), a small-molecule cyclin-dependent kinase inhibitor, mediates activity via down-regulation of Mcl-1 in multiple myeloma.
Blood 2005;106(3):1042-7.
2005: Hiroshi Yasui; Teru Hideshima; Makoto Hamasaki; Aldo Roccaro; Norihiko Shiraishi; Shaji Kumar; Pierfrancesco Tassone; Kenji Ishitsuka; Noopur Raje; Yu-Tzu Tai; klaus podar; Dharminder Chauhan; Lorenzo Leoni; Sarath Kanekal; Gary Elliott; Nikhil C Munshi; Kenneth C Anderson
SDX-101, the R-enantiomer of etodolac, induces cytotoxicity, overcomes drug resistance, and enhances the activity of dexamethasone in multiple myeloma.
Blood 2005;106(2):706-12.
2005: Shaji Kumar; Noopur Raje; Teru Hideshima; Kenji Ishitsuka; Aldo Roccaro; Norihiko Shiraishi; Makoto Hamasaki; Hiroshi Yasui; Nikhil C Munshi; Paul Richardson; W D Figg; Kenneth C Anderson
Antimyeloma activity of two novel N-substituted and tetraflourinated thalidomide analogs.
Leukemia 2005;19(7):1253-61.
2005: Makoto Hamasaki; Teru Hideshima; Pierfrancesco Tassone; Paola Neri; Kenji Ishitsuka; Hiroshi Yasui; Norihiko Shiraishi; Noopur Raje; Shaji Kumar; Donald Picker; Gary S Jacob; Paul G Richardson; Nikhil C Munshi; Kenneth C Anderson
Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivo.
Blood 2005;105(11):4470-6.
2005: Teru Hideshima; Dharminder Chauhan; Kenji Ishitsuka; Hiroshi Yasui; Noopur Raje; Shaji Kumar; klaus podar; Constantine S Mitsiades; Hiromasa Hideshima; Lynn Bonham; Nikhil C Munshi; Paul G Richardson; Jack W Singer; Kenneth C Anderson
Molecular characterization of PS-341 (bortezomib) resistance: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-beta inhibitors.
Oncogene 2005;24(19):3121-9.
2005: Hiroshi Yasui; Masaaki Adachi; Hirofumi Hamada; Kohzoh Imai
Adenovirus-mediated gene transfer of caspase-8 sensitizes human adenocarcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand.
International journal of oncology 2005;26(2):537-44.
2005: Toshiaki Hayashi; Teru Hideshima; Masaharu Akiyama; klaus podar; Hiroshi Yasui; Noopur Raje; Shaji Kumar; Dharminder Chauhan; Steve P Treon; Paul G Richardson; Kenneth C Anderson
Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application.
British journal of haematology 2005;128(2):192-203.
2004: Toshiaki Hayashi; Teru Hideshima; Aaron N Nguyen; Olivier Munoz; klaus podar; Makoto Hamasaki; Kenji Ishitsuka; Hiroshi Yasui; Paul Richardson; Sarvajit Chakravarty; Alison Murphy; Dharminder Chauhan; Linda S Higgins; Kenneth C Anderson
Transforming growth factor beta receptor I kinase inhibitor down-regulates cytokine secretion and multiple myeloma cell growth in the bone marrow microenvironment.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(22):7540-6.