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Yutaka Yatomi

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Kenichiro Enooku; Hitoshi Ikeda; Reiko Kato; Yukio Kume; Makoto Kurano; Tomoko Ono; Toru Suzuki; Tsutomu Yamazaki; Kenichi Aizawa; Haruhiko Yoshida; Yutaka Yatomi
Inverse correlations between serum ADAMTS13 levels and systolic blood pressure, pulse pressure, and serum C-reactive protein levels observed at a general health examination in a Japanese population: A cross-sectional study.
Naoko Watanabe-Okochi; Yutaka Yatomi; Hiromitsu Yokota; Akihide Yoshimi; Toshiyuki Ikeda; Toshio Kitamura; Jiro Kitaura; Keiki Kumano; Akiko Masuda; Tomohiko Sato; Yumiko Satoh; Akihito Shinohara; Koki Takahashi; Kazuki Taoka; Takako Tsuruta; Mineo Kurokawa
The shortest isoform of C/EBPβ, liver inhibitory protein (LIP), collaborates with Evi1 to induce AML in a mouse BMT model.
Hiromi Hikita; Kenichiro Enooku; Hiroaki Gotoh; Tomomi Iwai; Kazuhiko Koike; Ryota Masuzaki; Hayato Nakagawa; Masao Omata; Mamiko Sato; Yoko Soroida; Atsushi Suzuki; Ryosuke Tateishi; Yutaka Yatomi; Hiromitsu Yokota; Haruhiko Yoshida; Hitoshi Ikeda
Perihepatic lymph node enlargement is a negative predictor of liver cancer development in chronic hepatitis C patients.

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2013: Kenichiro Enooku; Hitoshi Ikeda; Reiko Kato; Yukio Kume; Makoto Kurano; Tomoko Ono; Toru Suzuki; Tsutomu Yamazaki; Kenichi Aizawa; Haruhiko Yoshida; Yutaka Yatomi
Inverse correlations between serum ADAMTS13 levels and systolic blood pressure, pulse pressure, and serum C-reactive protein levels observed at a general health examination in a Japanese population: A cross-sectional study.
Clinica chimica acta; international journal of clinical chemistry 2013;421():147-51.
2013: Naoko Watanabe-Okochi; Yutaka Yatomi; Hiromitsu Yokota; Akihide Yoshimi; Toshiyuki Ikeda; Toshio Kitamura; Jiro Kitaura; Keiki Kumano; Akiko Masuda; Tomohiko Sato; Yumiko Satoh; Akihito Shinohara; Koki Takahashi; Kazuki Taoka; Takako Tsuruta; Mineo Kurokawa
The shortest isoform of C/EBPβ, liver inhibitory protein (LIP), collaborates with Evi1 to induce AML in a mouse BMT model.
Blood 2013;121(20):4142-55.
2013: Hiromi Hikita; Kenichiro Enooku; Hiroaki Gotoh; Tomomi Iwai; Kazuhiko Koike; Ryota Masuzaki; Hayato Nakagawa; Masao Omata; Mamiko Sato; Yoko Soroida; Atsushi Suzuki; Ryosuke Tateishi; Yutaka Yatomi; Hiromitsu Yokota; Haruhiko Yoshida; Hitoshi Ikeda
Perihepatic lymph node enlargement is a negative predictor of liver cancer development in chronic hepatitis C patients.
Journal of gastroenterology 2013;48(3):366-73.
2013: Hayakazu Sumida; Kunihiko Tamaki; Keisuke Yanagida; Junken Aoki; Yoshihide Asano; Koji Igarashi; Satoshi Ishii; Takafumi Kadono; Kazuhiro Nakamura; Ryunosuke Ohkawa; Shinichi Sato; Takao Shimizu; Yutaka Yatomi
Decrease in circulating autotaxin by oral administration of prednisolone.
Clinica chimica acta; international journal of clinical chemistry 2013;415():74-80.
2013: Masanori Kawakami; Shigeki Morita; Takahide Nagase; Jun Nakajima; Nobuya Ohishi; Mitsuhiro Sunohara; Yosuke Amano; Masashi Fukayama; Emi Hamano; Rie Ishikawa; Kousuke Watanabe; Yutaka Yatomi; Daiya Takai
FER overexpression is associated with poor postoperative prognosis and cancer-cell survival in non-small cell lung cancer.
International journal of clinical and experimental pathology 2013;6(4):598-612.
2013: Yoshikazu Ono; Minoru Tozuka; Hiromitsu Yokota; Junken Aoki; Koji Igarashi; Makoto Kurano; Ryunosuke Ohkawa; Yutaka Yatomi
Sphingosine 1-phosphate release from platelets during clot formation: close correlation between platelet count and serum sphingosine 1-phosphate concentration.
Lipids in health and disease 2013;12():20.
2013: Naminatsu Takahara; Daiya Takai; Rie Uchino; Natsuyo Yamamoto; Yutaka Yatomi; Tsuyoshi Hamada; Kenji Hirano; Hideaki Ijichi; Hiroyuki Isayama; Kazumichi Kawakubo; Hirofumi Kogure; Koji Miyabayashi; Suguru Mizuno; Dai Mohri; Yousuke Nakai; Naoki Sasahira; Takashi Sasaki; Yumiko Satoh; Minoru Tada; Kazuhiko Koike
Uridine diphosphate glucuronosyl transferase 1 family polypeptide A1 gene (UGT1A1) polymorphisms are associated with toxicity and efficacy in irinotecan monotherapy for refractory pancreatic cancer.
Cancer chemotherapy and pharmacology 2013;71(1):85-92.
2013: Hitoshi Ikeda; Kazuhiko Koike; Ryunosuke Ohkawa; Kenichiro Enooku; Yutaka Yatomi
Plasma lysophosphatidic acid levels and hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2013;57(1):417-8.
2012: Nobuko Kanno; Kumiko Tanabe; Masahiro Jyona; Makoto Kaneko; Hiromitsu Yokota; Yutaka Yatomi
[Condition setting for the measurement of blood coagulation factor XIII activity using a fully automated blood coagulation analyzer, COAGTRON-350].
Rinsho byori. The Japanese journal of clinical pathology 2012;60(12):1131-8.
2012: Ryunosuke Ohkawa; Shigeo Okubo; Noboru Sakai; Kansei Uno; Hiromitsu Yokota; Hiroyuki Daida; Tomotaka Dohi; Naoto Hayashi; Hitoshi Ikeda; Tatsuya Kishimoto; Makoto Kurano; Naoto Matsuyama; Katsumi Miyauchi; Mika Nagasaki; Kazuhiro Nakamura; Takahiro Nojiri; Yutaka Yatomi
Development of an enzymatic assay for sphingomyelin with rapid and automatable performances: Analysis in healthy subjects and coronary heart disease patients.
Clinical biochemistry 2012;45(16-17):1463-70.
2012: Rie Maruo; Yumiko Sato; Kenichi Syukuya; Yuko Kageyama; Hiromitsu Yokota; Yutaka Yatomi
[Usefulness of hepatitis C virus (HCV) genotype test using direct sequencing of 5' untranslated region--application from 2003 to 2011].
Rinsho byori. The Japanese journal of clinical pathology 2012;60(10):927-31.
2012: Yuko Kageyama; Kazuhiko Koike; Takatoshi Koyama; Yoshika Kusumoto; Masakazu Nagamine; Takako Nishikawa; Natsuko Ohtomo; Yasuo Okamoto; Yumiko Satoh; Tatsuo Shimosawa; Koji Shinozaki; Yoh Takuwa; Yasushi Tanoue; Tomoaki Tomiya; Naoko Watanabe; Mitsuru Yashiro; Hitoshi Ikeda; Yukiko Inoue; Kazuhiro Ishimaru; Hiromitsu Yokota; Yutaka Yatomi
Antagonism of sphingosine 1-phosphate receptor 2 causes a selective reduction of portal vein pressure in bile duct-ligated rodents.
Hepatology (Baltimore, Md.) 2012;56(4):1427-38.
2012: Shinji Sone; Koki Takahashi; Hiromitu Yokota; Yutaka Yatomi
[Introduction of preventive measures toward contact infection without affecting the efficiency of the outpatient blood collection].
Rinsho byori. The Japanese journal of clinical pathology 2012;60(9):853-9.
2012: Kazuhiro Nakamura; Ryunosuke Ohkawa; Tetsu Yano; Junken Aoki; Koji Igarashi; Hitoshi Ikeda; Akiko Masuda; Shunsuke Nakagawa; Hiromitsu Yokota; Yutaka Yatomi
Serum autotaxin is not a useful biomarker for ovarian cancer.
Lipids 2012;47(9):927-30.
2012: Yumiko Satoh; Daiya Takai; Hiromitsu Yokota; Yutaka Yatomi
[Study on the analytical error factors and evaluation of an internal control gene for leukemia gene expression analysis].
Rinsho byori. The Japanese journal of clinical pathology 2012;60(8):740-7.
2012: Yoko Soroida; Ryosuke Tateishi; Yutaka Yatomi; Hiromitsu Yokota; Haruhiko Yoshida; Kenichiro Enooku; Tadashi Hoshino; Hiroto Kinoshita; Kazuhiko Koike; Ryota Masuzaki; Ritsuko Nagatomo; Hayato Nakagawa; Shuntaro Obi; Ryunosuke Ohkawa; Shigeo Okubo; Takahisa Sato; Yumiko Satoh; Shuichiro Shiina; Hitoshi Ikeda
Increased activity of serum mitochondrial isoenzyme of creatine kinase in hepatocellular carcinoma patients predominantly with recurrence.
Journal of hepatology 2012;57(2):330-6.
2012: Satoshi Ono; Yu Takahashi; Yosuke Tsuji; Nobutake Yamamichi; Yutaka Yatomi; Itsuko Asada-Hirayama; Mitsuhiro Fujishiro; Makoto Kaneko; Shinya Kodashima; Maki Konno-Shimizu; Rie Mikami-Matsuda; Chihiro Minatsuki; Satoshi Mochizuki; Keiko Niimi; Kazuhiko Koike
Evaluation of safety of endoscopic biopsy without cessation of antithrombotic agents in Japan.
Journal of gastroenterology 2012;47(7):770-4.
2012: Makoto Osada; Guo Ding; Hideki Fujii; Masanori Hirashima; Kazuyoshi Hirayama; Hirotake Ichise; Osamu Inoue; Toshiaki Shirai; Katsue Suzuki-Inoue; Katsuhiro Takano; Yutaka Yatomi; Yukio Ozaki
Platelet activation receptor CLEC-2 regulates blood/lymphatic vessel separation by inhibiting proliferation, migration, and tube formation of lymphatic endothelial cells.
The Journal of biological chemistry 2012;287(26):22241-52.
2012: Yutaka Yatomi
[From FAB classification to WHO classification of tumors of hematopoietic and lymphoid tissue].
Rinsho byori. The Japanese journal of clinical pathology 2012;60(6):550-2.
2012: Tomonori Sugiura; Sumiyo Yamashita; Yutaka Yatomi; Yasuaki Dohi; Yuji Hirowatari; Shiori Ito; Soichiro Iwaki; Genjiro Kimura; Yuko Mishima; Ryunosuke Ohkawa; Nobuyuki Ohte; Satoshi Fujii
Analytical evaluation of plasma serotonin and sphingosine 1-phosphate and their clinical assessment in early atherosclerosis.
Coronary artery disease 2012;23(4):234-8.
2012: Makoto Osada; Masumi Endoh; Nobuyuki Enomoto; Osamu Inoue; Makoto Kaneko; Minoru Sakamoto; Kaneo Satoh; Katsue Suzuki-Inoue; Koichi Takigawa; Yutaka Yatomi; Yukio Ozaki
Causes of thrombocytopenia in chronic hepatitis C viral infection.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2012;18(3):272-80.
2012: Kousuke Watanabe; Yutaka Yatomi; Noriko Emoto; Masashi Fukayama; Akiteru Goto; Emi Hamano; Hidenori Kage; Masanori Kawakami; Kentaro Kitano; Takahide Nagase; Jun Nakajima; Nobuya Ohishi; Mitsuhiro Sunohara; Daiya Takai
Genome structure-based screening identified epigenetically silenced microRNA associated with invasiveness in non-small-cell lung cancer.
International journal of cancer. Journal international du cancer 2012;130(11):2580-90.
2012: Koichi Kimura; Hiroyuki Morita; Jiro Ando; Aya Ebihara; Hideo Fujita; Nobuaki Fukuda; Tomoko Okano; Katsu Takenaka; Kansei Uno; Yutaka Yatomi; Ryozo Nagai
Speckle tracking global strain rate E/E' predicts LV filling pressure more accurately than traditional tissue Doppler E/E'.
Echocardiography (Mount Kisco, N.Y.) 2012;29(4):404-10.
2012: Jun Araki; Kentaro Doi; Hitomi Eto; Masahiro Jona; Harunosuke Kato; Hirotaka Suga; Yutaka Yatomi; Noriyuki Aoi; Kotaro Yoshimura
Optimized preparation method of platelet-concentrated plasma and noncoagulating platelet-derived factor concentrates: maximization of platelet concentration and removal of fibrinogen.
Tissue engineering. Part C, Methods 2012;18(3):176-85.
2012: Fumiko Kawakami-Mori; Shengyu Mu; Sayoko Ogura; Tatsuo Shimosawa; Hong Wang; Yutaka Yatomi; Toshiro Fujita
NADPH oxidase-mediated Rac1 GTP activity is necessary for nongenomic actions of the mineralocorticoid receptor in the CA1 region of the rat hippocampus.
American journal of physiology. Endocrinology and metabolism 2012;302(4):E425-32.
2012: Yumiko Satoh; Yasuhiro Seto; Hiroshi Uozaki; Yutaka Yatomi; Hiromitsu Yokota; Masashi Fukayama; Kentaro Kitano; Joji Kitayama; Kazuhiko Mori; Hirokazu Nagawa; Hiroki Sasaki; Daiya Takai
Analysis for the combination expression of CK20, FABP1 and MUC2 is sensitive for the prediction of peritoneal recurrence in gastric cancer.
Japanese journal of clinical oncology 2012;42(2):148-52.
2011: Kentaro Kitano; Tomohiro Murakawa; Takahide Nagase; Jun Nakajima; Nobuya Ohishi; Atsushi Sano; Noriko Emoto; Masashi Fukayama; Akiteru Goto; Emi Hamano; Hidenori Kage; Kousuke Watanabe; Yutaka Yatomi; Daiya Takai
CpG island methylation of microRNAs is associated with tumor size and recurrence of non-small-cell lung cancer.
Cancer science 2011;102(12):2126-31.
2011: Yutaka Yatomi
[Update information for physicians on laboratory tests: recent progress in clinical laboratory testing. Topics: II. Particulars with special emphasis on novel laboratory tests; 4. Hematological diseases, 2) Thrombosis and hemostasis laboratory tests].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(11):3240-6.
2011: Koichi Kimura; Takahide Kohro; Hiroyuki Morita; Masataka Sata; Katsu Takenaka; Kansei Uno; Yutaka Yatomi; Aya Ebihara; Hiroshi Iwata; Ryozo Nagai
Reproducibility and diagnostic accuracy of three-layer speckle tracking echocardiography in a swine chronic ischemia model.
Echocardiography (Mount Kisco, N.Y.) 2011;28(10):1148-55.
2011: Akiko Masuda; Kazuhiro Nakamura; Ryunosuke Ohkawa; Shinichi Okudaira; Junken Aoki; Tomoyuki Fujii; Koji Igarashi; Hitoshi Ikeda; Yuki Iwasawa; Shiro Kozuma; Yutaka Yatomi
Serum autotaxin measurements in pregnant women: application for the differentiation of normal pregnancy and pregnancy-induced hypertension.
Clinica chimica acta; international journal of clinical chemistry 2011;412(21-22):1944-50.
2011: Hitoshi Ikeda; Yukiko Inoue; Kazuhiko Koike; Yuji Kondo; Yukio Kume; Ryota Masuzaki; Hayato Nakagawa; Takako Nishikawa; Natsuko Ohtomo; Tomoko Ono; Shuichiro Shiina; Yasushi Tanoue; Ryosuke Tateishi; Tomoaki Tomiya; Kenichiro Enooku; Tadashi Goto; Haruhiko Yoshida; Yutaka Yatomi
Prediction of hepatocellular carcinoma development by plasma ADAMTS13 in chronic hepatitis B and C.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011;20(10):2204-11.
2011: Hayato Nakagawa; Hitoshi Ikeda; Kazuhiro Nakamura; Ryunosuke Ohkawa; Ryota Masuzaki; Ryosuke Tateishi; Haruhiko Yoshida; Naoko Watanabe; Kazuaki Tejima; Yukio Kume; Tomomi Iwai; Atsushi Suzuki; Tomoaki Tomiya; Yukiko Inoue; Takako Nishikawa; Natsuko Ohtomo; Yasushi Tanoue; Masao Omata; Koji Igarashi; Junken Aoki; Kazuhiko Koike; Yutaka Yatomi
Autotaxin as a novel serum marker of liver fibrosis.
Clinica chimica acta; international journal of clinical chemistry 2011;412(13-14):1201-6.
2011: Ritsuko Nagatomo; Yoshikazu Ono; Kojiro Ueki; Takashi Kadowaki; Makoto Kaneko; Nobuko Kanno; Kaoru Yuasa; Yutaka Yatomi
[Questionnaire survey of the POCT device antsense ROSE for blood glucose analysis on healthcare professionals--evaluation focused on preventive measures against cross-infections].
Rinsho byori. The Japanese journal of clinical pathology 2011;59(6):577-82.
2011: Yousuke Nakai; Hitoshi Ikeda; Kazuhiro Nakamura; Yukio Kume; Mitsuhiro Fujishiro; Naoki Sasahira; Kenji Hirano; Hiroyuki Isayama; Minoru Tada; Takao Kawabe; Yutaka Komatsu; Masao Omata; Junken Aoki; Kazuhiko Koike; Yutaka Yatomi
Specific increase in serum autotaxin activity in patients with pancreatic cancer.
Clinical biochemistry 2011;44(8-9):576-81.
2011: ShengYu Mu; Tatsuo Shimosawa; Sayoko Ogura; Hong Wang; Yuzaburo Uetake; Fumiko Kawakami-Mori; Takeshi Marumo; Yutaka Yatomi; David S Geller; Hirotoshi Tanaka; Toshiro Fujita
Epigenetic modulation of the renal β-adrenergic-WNK4 pathway in salt-sensitive hypertension.
Nature medicine 2011;17(5):573-80.
2011: Koichi Kimura; Katsu Takenaka; XiaoFang Pan; Aya Ebihara; Kansei Uno; Nobuaki Fukuda; Takahide Kohro; Hiroyuki Morita; Yutaka Yatomi; Ryozo Nagai
Prediction of coronary artery stenosis using strain imaging diastolic index at rest in patients with preserved ejection fraction.
Journal of cardiology 2011;57(3):311-5.
2011: Nobuko Kanno; Makoto Kaneko; Yutaka Yatomi
[Japanese Ministry of Health, Labour and Welfare DIC diagnostic criteria].
Rinsho byori. The Japanese journal of clinical pathology 2011;Suppl 147():31-5.
2011: Naomi Watanabe; Ritsuko Nagatomo; Shigeo Okubo; Hiromitsu Yokota; Hitoshi Ikeda; Yutaka Yatomi
[Evaluation of latex agglutination test for anti-treponemal antibody in comparison with chemical luminescence tests].
Rinsho byori. The Japanese journal of clinical pathology 2011;59(2):115-20.
2011: Ritsuko Nagatomo; Naomi Watanabe; Shigeo Okubo; Hiromitsu Yokota; Hitoshi Ikeda; Yutaka Yatomi
[The comparison study between UniCAP EliA and former kit for measuring the autoantibodies].
Rinsho byori. The Japanese journal of clinical pathology 2011;59(1):31-6.
2010: Katsue Suzuki-Inoue; Osamu Inoue; Guo Ding; Satoshi Nishimura; Kazuya Hokamura; Koji Eto; Hirokazu Kashiwagi; Yoshiaki Tomiyama; Yutaka Yatomi; Kazuo Umemura; Yonchol Shin; Masanori Hirashima; Yukio Ozaki
Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets.
The Journal of biological chemistry 2010;285(32):24494-507.
2010: Kazuhiro Nakamura; Koji Igarashi; Ryunosuke Ohkawa; Naoya Saiki; Mika Nagasaki; Kansei Uno; Naoto Hayashi; Tetsuji Sawada; Kenichi Syukuya; Hiromitsu Yokota; Hiroyuki Arai; Hitoshi Ikeda; Junken Aoki; Yutaka Yatomi
A novel enzyme immunoassay for the determination of phosphatidylserine-specific phospholipase A(1) in human serum samples.
Clinica chimica acta; international journal of clinical chemistry 2010;411(15-16):1090-4.
2010: Kazuaki Tejima; Ryota Masuzaki; Hitoshi Ikeda; Haruhiko Yoshida; Ryosuke Tateishi; Yosuke Sugioka; Yukio Kume; Tomoko Okano; Tomomi Iwai; Hiroaki Gotoh; Sachiko Katoh; Atsushi Suzuki; Yukako Koike; Yutaka Yatomi; Masao Omata; Kazuhiko Koike
Thrombocytopenia is more severe in patients with advanced chronic hepatitis C than B with the same grade of liver stiffness and splenomegaly.
Journal of gastroenterology 2010;45(8):876-84.
2010: Kazuhiro Nakamura; Yutaka Yatomi
[Lysophospholipids].
Nihon rinsho. Japanese journal of clinical medicine 2010;68 Suppl 7():853-5.
2010: Shigeo Okubo; Hiromitsu Yokota; Hitoshi Ikeda; Yutaka Yatomi
[Overview of ISO15189 and accreditation with it].
Rinsho byori. The Japanese journal of clinical pathology 2010;58(7):676-84.
2010: Yutaka Yatomi
[Clinical introduction of lysophosphatidic acid and autotaxin assays].
Rinsho byori. The Japanese journal of clinical pathology 2010;58(6):631-5.
2010: Xun Qi; Yasuo Okamoto; Tomomi Murakawa; Fei Wang; Osamu Oyama; Ryunosuke Ohkawa; Kazuaki Yoshioka; Wa Du; Naotoshi Sugimoto; Yutaka Yatomi; Noriko Takuwa; Yoh Takuwa
Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice.
European journal of pharmacology 2010;634(1-3):121-31.
2010: Hitoshi Ikeda; Ryunosuke Ohkawa; Naoko Watanabe; Kazuhiro Nakamura; Yukio Kume; Hayato Nakagawa; Haruhiko Yoshida; Shigeo Okubo; Hiromitsu Yokota; Tomoaki Tomiya; Yukiko Inoue; Takako Nishikawa; Natsuko Ohtomo; Yasushi Tanoue; Kazuhiko Koike; Yutaka Yatomi
Plasma concentration of bioactive lipid mediator sphingosine 1-phosphate is reduced in patients with chronic hepatitis C.
Clinica chimica acta; international journal of clinical chemistry 2010;411(9-10):765-70.
2010: Masashi Kusakabe; Tomoko Kutomi; Kousuke Watanabe; Noriko Emoto; Naomi Aki; Hidenori Kage; Emi Hamano; Hiroshi Kitagawa; Takahide Nagase; Atsushi Sano; Yukihiro Yoshida; Takeshi Fukami; Tomohiro Murakawa; Jun Nakajima; Shinichi Takamoto; Satoshi Ota; Masashi Fukayama; Yutaka Yatomi; Nobuya Ohishi; Daiya Takai
Identification of G0S2 as a gene frequently methylated in squamous lung cancer by combination of in silico and experimental approaches.
International journal of cancer. Journal international du cancer 2010;126(8):1895-902.
2010: Hideo Ogiso; Kazuhiro Nakamura; Yutaka Yatomi; Takao Shimizu; Ryo Taguchi
Liquid chromatography/mass spectrometry analysis revealing preferential occurrence of non-arachidonate-containing phosphatidylinositol bisphosphate species in nuclei and changes in their levels during cell cycle.
Rapid communications in mass spectrometry : RCM 2010;24(4):436-42.
2010: Yukako Koike; Koji Miyazaki; Masaaki Higashihara; Emiko Kimura; Masahiro Jona; Kinya Uchihashi; Akiko Masuda; Koji Kandabashi; Mineo Kurokawa; Yutaka Yatomi
Clinical significance of detection of immature platelets: comparison between percentage of reticulated platelets as detected by flow cytometry and immature platelet fraction as detected by automated measurement.
European journal of haematology 2010;84(2):183-4.
2009: Masashi Kusakabe; Kousuke Watanabe; Noriko Emoto; Naomi Aki; Hidenori Kage; Takahide Nagase; Jun Nakajima; Yutaka Yatomi; Nobuya Ohishi; Daiya Takai
Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists.
Biochemical and biophysical research communications 2009;390(4):1283-7.
2009: Hiromitsu Yokota; Yutaka Yatomi
[Chromosome analysis of and genetic testing for myeloid leukemia].
Nihon rinsho. Japanese journal of clinical medicine 2009;67(10):1911-5.
2009: Naoko Watanabe; Hitoshi Ikeda; Yukio Kume; Yumiko Satoh; Makoto Kaneko; Daiya Takai; Kazuaki Tejima; Masakazu Nagamine; Hirosato Mashima; Tomoaki Tomiya; Eisei Noiri; Masao Omata; Masanori Matsumoto; Yoshihiro Fujimura; Yutaka Yatomi
Increased production of ADAMTS13 in hepatic stellate cells contributes to enhanced plasma ADAMTS13 activity in rat models of cholestasis and steatohepatitis.
Thrombosis and haemostasis 2009;102(2):389-96.
2009: Yuki Iwasawa; Tomoyuki Fujii; Takeshi Nagamatsu; Kei Kawana; Shinichi Okudaira; Shiho Miura; Junko Matsumoto; Ayako Tomio; Hironobu Hyodo; Takahiro Yamashita; Katsutoshi Oda; Shiro Kozuma; Junken Aoki; Yutaka Yatomi; Yuji Taketani
Expression of autotaxin, an ectoenzyme that produces lysophosphatidic acid, in human placenta.
American journal of reproductive immunology (New York, N.Y. : 1989) 2009;62(2):90-5.
2009: Shigeo Okubo; Hiromitsu Yokota; Yutaka Yatomi
[The management of panic values in the field of clinical chemistry].
Rinsho byori. The Japanese journal of clinical pathology 2009;57(7):671-7.
2009: Hitoshi Ikeda; Naoko Watanabe; Kazuhiro Nakamura; Yukio Kume; Yousuke Nakai; Mitsuhiro Fujishiro; Masao Omata; Koji Igarashi; Hiromitsu Yokota; Yutaka Yatomi
[Significance of serum autotaxin activity in gastrointestinal disease].
Rinsho byori. The Japanese journal of clinical pathology 2009;57(5):445-9.
2009: Yosuke Masamoto; Yasuhito Nannya; Syunya Arai; Yukako Koike; Akira Hangaishi; Yutaka Yatomi; Mineo Kurokawa
Evidence for basophilic differentiation of acute promyelocytic leukaemia cells during arsenic trioxide therapy.
British journal of haematology 2009;144(5):798-9.
2009: Hitoshi Ikeda; Naoko Watanabe; Isao Ishii; Tatsuo Shimosawa; Yukio Kume; Tomoaki Tomiya; Yukiko Inoue; Takako Nishikawa; Natsuko Ohtomo; Yasushi Tanoue; Satoko Iitsuka; Ryoto Fujita; Masao Omata; Jerold Chun; Yutaka Yatomi
Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2.
Journal of lipid research 2009;50(3):556-64.
2009: Yumiko Satoh; Xin Li; Hiromitsu Yokota; Makoto Osada; Yukio Ozaki; Ryohei Katoh; Yutaka Yatomi
Regulation by sphingolipids of the fate of FRTL-5 cells.
Journal of biochemistry 2009;145(1):31-6.
2008: Atsushi Kimura; Tsukasa Ohmori; Yuji Kashiwakura; Ryunosuke Ohkawa; Seiji Madoiwa; Jun Mimuro; Kuniko Shimazaki; Yuichi Hoshino; Yutaka Yatomi; Yoichi Sakata
Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain.
Stroke; a journal of cerebral circulation 2008;39(12):3411-7.
2008: Akiko Masuda; Kazuhiro Nakamura; Koji Izutsu; Koji Igarashi; Ryunosuke Ohkawa; Masahiro Jona; Katsumi Higashi; Hiromitsu Yokota; Shinichi Okudaira; Tatsuya Kishimoto; Takuro Watanabe; Yukako Koike; Hitoshi Ikeda; Yasushi Kozai; Mineo Kurokawa; Junken Aoki; Yutaka Yatomi
Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma.
British journal of haematology 2008;143(1):60-70.
2008: Hiromitsu Yokota; Yumiko Satoh; Yoshikazu Ono; Makoto Kaneko; Hitoshi Ikeda; Shoji Tsuji; Yutaka Yatomi
[Establishment of a pharmacogenomic testing system for the realization of individual pharmacotherapy].
Rinsho byori. The Japanese journal of clinical pathology 2008;56(9):772-80.
2008: Yasuhito Nannya; Hiromitsu Yokota; Yumiko Sato; Go Yamamoto; Takashi Asai; Motoshi Ichikawa; Takuro Watanabe; Keiki Kumano; Akira Hangaishi; Tsuyoshi Takahashi; Shigeru Chiba; Yutaka Yatomi; Mineo Kurokawa
Molecular and cytogenetic response of chronic myelogenous leukemia treated with imatinib mesylate: one institutional experience in Japan.
International journal of hematology 2008;88(2):159-64.
2008: Shigemi Hosogaya; Yutaka Yatomi; Kazuhiro Nakamura; Ryunosuke Ohkawa; Shigeo Okubo; Hiromitsu Yokota; Masato Ohta; Hirokazu Yamazaki; Toru Koike; Yukio Ozaki
Measurement of plasma lysophosphatidic acid concentration in healthy subjects: strong correlation with lysophospholipase D activity.
Annals of clinical biochemistry 2008;45(Pt 4):364-8.
2008: Ryunosuke Ohkawa; Kazuhiro Nakamura; Shigeo Okubo; Shigemi Hosogaya; Yukio Ozaki; Minoru Tozuka; Noriko Osima; Hiromitsu Yokota; Hitoshi Ikeda; Yutaka Yatomi
Plasma sphingosine-1-phosphate measurement in healthy subjects: close correlation with red blood cell parameters.
Annals of clinical biochemistry 2008;45(Pt 4):356-63.
2008: Hong Wang; Tatsuo Shimosawa; Hiromitsu Matsui; Tomoyo Kaneko; Sayoko Ogura; Yuzaburo Uetake; Katsu Takenaka; Yutaka Yatomi; Toshiro Fujita
Paradoxical mineralocorticoid receptor activation and left ventricular diastolic dysfunction under high oxidative stress conditions.
Journal of hypertension 2008;26(7):1453-62.
2008: Tatsuo Shimosawa; Tomoyo Kaneko; Yusaburo Uetake; Yusei Miyamoto; Hiromitsu Matsui; Hong Wang; Shengyu Mu; Rika Saito; Sayoko Ogura; Yutaka Yatomi; Toshiro Fujita
[Atherosclerosis and oxidative stress].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2008;45(3):287-90.
2008: Yumiko Satoh; Hiromitsu Yokota; Yuko Kageyama; Yoshikazu Ono; Yutaka Yatomi
[The current status of leukemia genetic testing and the trial of its standardization].
Rinsho byori. The Japanese journal of clinical pathology 2008;56(5):395-401.
2008: Ryosuke Makita; Yasunobu Uchijima; Koichi Nishiyama; Tomokazu Amano; Qin Chen; Takumi Takeuchi; Akihisa Mitani; Takahide Nagase; Yutaka Yatomi; Hiroyuki Aburatani; Osamu Nakagawa; Erin V Small; Patricia Cobo-Stark; Peter Igarashi; Masao Murakami; Junji Tominaga; Takahiro Sato; Tomoichiro Asano; Yukiko Kurihara; Hiroki Kurihara
Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.
American journal of physiology. Renal physiology 2008;294(3):F542-53.
2008: Yutaka Yatomi
Plasma sphingosine 1-phosphate metabolism and analysis.
Biochimica et biophysica acta 2008;1780(3):606-11.
2008: Kazuhiro Nakamura; Koji Igarashi; Kazufumi Ide; Ryunosuke Ohkawa; Shigeo Okubo; Hiromitsu Yokota; Akiko Masuda; Noriko Oshima; Takumi Takeuchi; Masaomi Nangaku; Shinichi Okudaira; Hiroyuki Arai; Hitoshi Ikeda; Junken Aoki; Yutaka Yatomi
Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation.
Clinica chimica acta; international journal of clinical chemistry 2008;388(1-2):51-8.
2008: Yutaka Yatomi
[Physiologically active substances derived from activated platelets: overview in clinical medicine].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2008;97(1):168-75.
2008: Kazuhiro Nakamura; Masaomi Nangaku; Ryunosuke Ohkawa; Shigeo Okubo; Hiromitsu Yokota; Hitoshi Ikeda; Junken Aoki; Yutaka Yatomi
Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2008;46(1):150-1.
2007: Sumimasa Nagai; Motoshi Ichikawa; Tsuyoshi Takahashi; Hiroyuki Sato; Hiromitsu Yokota; Kumi Oshima; Koji Izutsu; Akira Hangaishi; Yoshinobu Kanda; Toru Motokura; Shigeru Chiba; Yutaka Yatomi; Mineo Kurokawa
The origin of neoplastic mast cells in systemic mastocytosis with AML1/ETO-positive acute myeloid leukemia.
Experimental hematology 2007;35(11):1747-52.
2007: Kazuhiro Nakamura; Takumi Takeuchi; Ryunosuke Ohkawa; Shigeo Okubo; Hiromitsu Yokota; Minoru Tozuka; Junken Aoki; Hiroyuki Arai; Hitoshi Ikeda; Noriko Ohshima; Tadaichi Kitamura; Yutaka Yatomi
Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker: study on prostate cancer patients.
Annals of clinical biochemistry 2007;44(Pt 6):549-56.
2007: Atsushi Sano; H Kage; Keiki Sugimoto; Hiroshi Kitagawa; N Aki; A Goto; M Fukayama; J Nakajima; S Takamoto; Takashi Nagase; Yutaka Yatomi; Nobuya Ohishi; Daiya Takai
A second-generation profiling system for quantitative methylation analysis of multiple gene promoters: application to lung cancer.
Oncogene 2007;26(45):6518-25.
2007: Hitoshi Ikeda; Yukio Kume; Kazuaki Tejima; Tomoaki Tomiya; Takako Nishikawa; Naoko Watanabe; Natsuko Ohtomo; Masahiro Arai; Chihiro Arai; Masao Omata; Kenji Fujiwara; Yutaka Yatomi
Rho-kinase inhibitor prevents hepatocyte damage in acute liver injury induced by carbon tetrachloride in rats.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(4):G911-7.
2007: Takeshi Kawanabe; Tamihiro Kawakami; Yutaka Yatomi; Shinji Shimada; Yoshinao Soma
Sphingosine 1-phosphate accelerates wound healing in diabetic mice.
Journal of dermatological science 2007;48(1):53-60.
2007: Katsue Suzuki-Inoue; Yukinari Kato; Osamu Inoue; Mika Kato Kaneko; Kazuhiko Mishima; Yutaka Yatomi; Yasuo Yamazaki; Hisashi Narimatsu; Yukio Ozaki
Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells.
The Journal of biological chemistry 2007;282(36):25993-6001.
2007: Tatsuo Shimosawa; Kengo Gohchi; Yutaka Yatomi; Toshiro Fujita
Effectiveness of add-on low-dose diuretics in combination therapy for hypertension: losartan/hydrochlorothiazide vs. candesartan/amlodipine.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(9):831-7.
2007: Naoko Watanabe; Hitoshi Ikeda; Kazuhiro Nakamura; Ryunosuke Ohkawa; Yukio Kume; Tomoaki Tomiya; Kazuaki Tejima; Takako Nishikawa; Masahiro Arai; Mikio Yanase; Junken Aoki; Hiroyuki Arai; Masao Omata; Kenji Fujiwara; Yutaka Yatomi
Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity.
Life sciences 2007;81(12):1009-15.
2007: Makoto Osada; Yutaka Yatomi; Tsukasa Ohmori; Shinya Aoki; Shigemi Hosogaya; Yukio Ozaki
Involvement of sphingosine 1-phosphate, a platelet-derived bioactive lipid, in contraction of mesangium cells.
Journal of biochemistry 2007;142(3):351-5.
2007: Keiki Sugimoto; Hidenori Kage; Naomi Aki; Atsushi Sano; Hiroshi Kitagawa; Takashi Nagase; Yutaka Yatomi; Nobuya Ohishi; Daiya Takai
The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus.
Biochemical and biophysical research communications 2007;359(3):497-502.
2007: Kazuhiro Nakamura; Tatsuya Kishimoto; Ryunosuke Ohkawa; Shigeo Okubo; Minoru Tozuka; Hiromitsu Yokota; Hitoshi Ikeda; Noriko Ohshima; Koji Mizuno; Yutaka Yatomi
Suppression of lysophosphatidic acid and lysophosphatidylcholine formation in the plasma in vitro: proposal of a plasma sample preparation method for laboratory testing of these lipids.
Analytical biochemistry 2007;367(1):20-7.
2007: Shinya Aoki; Makoto Osada; Makoto Kaneko; Yukio Ozaki; Yutaka Yatomi
Fluid shear stress enhances the sphingosine 1-phosphate responses in cell-cell interactions between platelets and endothelial cells.
Biochemical and biophysical research communications 2007;358(4):1054-7.
2007: Naoko Watanabe; Hitoshi Ikeda; Kazuhiro Nakamura; Ryunosuke Ohkawa; Yukio Kume; Junken Aoki; Kotaro Hama; Shinichi Okudaira; Masayuki Tanaka; Tomoaki Tomiya; Mikio Yanase; Kazuaki Tejima; Takako Nishikawa; Masahiro Arai; Hiroyuki Arai; Masao Omata; Kenji Fujiwara; Yutaka Yatomi
Both plasma lysophosphatidic acid and serum autotaxin levels are increased in chronic hepatitis C.
Journal of clinical gastroenterology 2007;41(6):616-23.
2007: Yumiko Satoh; Ryunosuke Ohkawa; Kazuhiro Nakamura; Katsumi Higashi; Makoto Kaneko; Hiromitsu Yokota; Junken Aoki; Hiroyuki Arai; Yasuhito Yuasa; Yutaka Yatomi
Lysophosphatidic acid protection against apoptosis in the human pre-B-cell line Nalm-6.
European journal of haematology 2007;78(6):510-7.
2007: Shinya Aoki; Yutaka Yatomi; T Shimosawa; Hiroharu Yamashita; Joji Kitayama; Nelson H Tsuno; Koki Takahashi; Yukio Ozaki
The suppressive effect of sphingosine 1-phosphate on monocyte-endothelium adhesion may be mediated by the rearrangement of the endothelial integrins alpha(5)beta(1) and alpha(v)beta(3).
Journal of thrombosis and haemostasis : JTH 2007;5(6):1292-301.
2007: Yukio Kume; Hitoshi Ikeda; Morihiro Inoue; Kazuaki Tejima; Tomoaki Tomiya; Takako Nishikawa; Naoko Watanabe; Tatsuya Ichikawa; Makoto Kaneko; Shigeo Okubo; Hiromitsu Yokota; Masao Omata; Kenji Fujiwara; Yutaka Yatomi
Hepatic stellate cell damage may lead to decreased plasma ADAMTS13 activity in rats.
FEBS letters 2007;581(8):1631-4.
2007: Kazuhiro Nakamura; Ryunosuke Ohkawa; Shigeo Okubo; Minoru Tozuka; Mitsumasa Okada; Shinya Aoki; Junken Aoki; Hiroyuki Arai; Hitoshi Ikeda; Yutaka Yatomi
Measurement of lysophospholipase D/autotaxin activity in human serum samples.
Clinical biochemistry 2007;40(3-4):274-7.
2007: Olga Cuyun-Lira; Makoto Kaneko; Toshiro Takafuta; Kaneo Satoh; Masatoshi Ohnishi; Yutaka Yatomi; Yoshio Ozaki
Inhibitory effects of ticlopidine on platelet function as assessed by three different methods.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;30(1):21-5.
2007: Atsushi Kimura; Tsukasa Ohmori; Ryunosuke Ohkawa; Seiji Madoiwa; Jun Mimuro; Takashi Murakami; Eiji Kobayashi; Yuichi Hoshino; Yutaka Yatomi; Yoichi Sakata
Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury.
Stem cells (Dayton, Ohio) 2007;25(1):115-24.
2006: Ryunosuke Ohkawa; Nobuo Hisano; Kazuhiro Nakamura; Shigeo Okubo; Hiromitsu Yokota; Yutaka Yatomi
Lysophospholipase D activity exists in the urine to catalyse the formation of lysophosphatidic acid.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(12):3612-3.
2006: Masayuki Tanaka; Shinichi Okudaira; Yasuhiro Kishi; Ryunosuke Ohkawa; Sachiko Iseki; Masato Ota; Sumihare Noji; Yutaka Yatomi; Junken Aoki; Hiroyuki Arai
Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid.
The Journal of biological chemistry 2006;281(35):25822-30.
2006: Yutaka Yatomi
[Elucidation of the functional roles of lysophospholipid mediators and its application in laboratory medicine].
Rinsho byori. The Japanese journal of clinical pathology 2006;54(7):720-31.
2006: Hitoshi Ikeda; Kayo Nagashima; Mikio Yanase; Tomoaki Tomiya; Masahiro Arai; Yukiko Inoue; Kazuaki Tejima; Takako Nishikawa; Naoko Watanabe; Kazuya Kitamura; Tomomi Isono; Naoya Yahagi; Eisei Noiri; Mie Inao; Satoshi Mochida; Yukio Kume; Yutaka Yatomi; Kazuhiko Nakahara; Masao Omata; Kenji Fujiwara
The herbal medicine inchin-ko-to (TJ-135) induces apoptosis in cultured rat hepatic stellate cells.
Life sciences 2006;78(19):2226-33.
2006: Hiroharu Yamashita; Joji Kitayama; Nobuko Kanno; Yutaka Yatomi; Hirokazu Nagawa
Hyperfibrinogenemia is associated with lymphatic as well as hematogenous metastasis and worse clinical outcome in T2 gastric cancer.
BMC cancer 2006;6():147.
2006: Yutaka Yatomi
Sphingosine 1-phosphate in vascular biology: possible therapeutic strategies to control vascular diseases.
Current pharmaceutical design 2006;12(5):575-87.
2006: Hiroharu Yamashita; Joji Kitayama; Dai Shida; Hironori Yamaguchi; Ken Mori; Makoto Osada; Shinya Aoki; Yutaka Yatomi; Yoh Takuwa; Hirokazu Nagawa
Sphingosine 1-phosphate receptor expression profile in human gastric cancer cells: differential regulation on the migration and proliferation.
The Journal of surgical research 2006;130(1):80-7.
2005: Ryunosuke Ohkawa; Yuji Hirowatari; Kazuhiro Nakamura; Shigeo Ohkubo; Hitoshi Ikeda; Mitsumasa Okada; Minoru Tozuka; Kazuhiko Nakahara; Yutaka Yatomi
Platelet release of beta-thromboglobulin and platelet factor 4 and serotonin in plasma samples.
Clinical biochemistry 2005;38(11):1023-6.
2005: Kazuhiro Nakamura; Yutaka Yatomi
[Lysophospholipids].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 8():809-11.
2005: Makoto Kaneko; Toshiro Takafuta; Olga Cuyun-Lira; Kaneo Satoh; Morio Arai; Yutaka Yatomi; Yukio Ozaki
Evaluation of platelet function under high shear condition in the small-sized collagen bead column.
The Journal of laboratory and clinical medicine 2005;146(2):64-75.
2005: Masato Yumoto; Maki Matsuda; Kenji Itoh; Akira Uno; Shotaro Karino; Osamu Saitoh; Yuu Kaneko; Yutaka Yatomi; Kimitaka Kaga
Auditory imagery mismatch negativity elicited in musicians.
Neuroreport 2005;16(11):1175-8.
2005: Shinya Aoki; Yutaka Yatomi; Masato Ohta; Makoto Osada; Fuminori Kazama; Kaneo Satoh; Kazuhiko Nakahara; Yukio Ozaki
Sphingosine 1-phosphate-related metabolism in the blood vessel.
Journal of biochemistry 2005;138(1):47-55.
2005: Masato Yumoto; Akira Uno; Kenji Itoh; Shotaro Karino; Osamu Saitoh; Yuu Kaneko; Yutaka Yatomi; Kimitaka Kaga
Audiovisual phonological mismatch produces early negativity in auditory cortex.
Neuroreport 2005;16(8):803-6.
2005: Tsukasa Ohmori; Yutaka Yatomi; Makoto Osada; Yoshio Ozaki
The intracellular action of sphingosine 1-phosphate in GPVI-mediated Ca2+ mobilization in platelets.
Thrombosis research 2005;115(5):409-15.
2004: Yutaka Yatomi
[Thrombomodulin].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 12():742-4.
2004: Dai Shida; Joji Kitayama; Hironori Yamaguchi; Hiroharu Yamashita; Ken Mori; Toshiaki Watanabe; Yutaka Yatomi; Hirokazu Nagawa
Sphingosine 1-phosphate transactivates c-Met as well as epidermal growth factor receptor (EGFR) in human gastric cancer cells.
FEBS letters 2004;577(3):333-8.
2004: Y Naganuma; Kaneo Satoh; Q Yi; Naoki Asazuma; Yutaka Yatomi; Yoshio Ozaki
Cleavage of platelet endothelial cell adhesion molecule-1 (PECAM-1) in platelets exposed to high shear stress.
Journal of thrombosis and haemostasis : JTH 2004;2(11):1998-2008.
2004: Yutaka Yatomi; Soichiro Yamamura; Nobuo Hisano; Kazuhiko Nakahara; Yasuyuki Igarashi; Yukio Ozaki
Sphingosine 1-phosphate breakdown in platelets.
Journal of biochemistry 2004;136(4):495-502.
2004: Hiromitsu Yokota; Yutaka Yatomi; Fumiko Mashige; Kazuhiko Nakahara
Expression of ceramide kinase in hematopoietic cells.
European journal of haematology 2004;73(4):307-8.
2004: Eiko Yokoo; Yutaka Yatomi; Toshiro Takafuta; Makoto Osada; Yoshitaka Okamoto; Yukio Ozaki
Sphingosine 1-phosphate inhibits migration of RBL-2H3 cells via S1P2: cross-talk between platelets and mast cells.
Journal of biochemistry 2004;135(6):673-81.
2004: Katsuhiro Takano; Naoki Asazuma; Kaneo Satoh; Yutaka Yatomi; Yukio Ozaki
Collagen-induced generation of platelet-derived microparticles in whole blood is dependent on ADP released from red blood cells and calcium ions.
Platelets 2004;15(4):223-9.
2004: Yutaka Yatomi; Akiko Yoneyama; Kazuhiko Nakahara
Usefulness of CD9 detection in the diagnosis of acute megakaryoblastic leukemia.
European journal of haematology 2004;72(3):229-30.
2004: Kaneo Satoh; Yutaka Yatomi; Takanori Osada; Satoshi Takeda; Naohiko Tsuyuguchi; Fumio Kubota; Yukio Ozaki
Clear visual detection of circulating platelet aggregates in acute myocardial infarction using a flow cytometer equipped with an imaging device.
Platelets 2004;15(1):61-2.
2004: Norihiko Amemiya; Yutaka Yatomi; Mitsuaki Yanagi; Takeshi Endo; Yukio Ozaki
Mixed blast crisis of chronic myelogenous leukemia involving minimally differentiated myeloblast and megakaryoblast lineages.
Laboratory hematology : official publication of the International Society for Laboratory Hematology 2004;10(4):254-5.
2003: Makoto Kaneko; Olga Cuyun-Lira; Toshiro Takafuta; Katsue Suzuki-Inoue; Kaneo Satoh; Kayoko Ohtsuki; Masatoshi Ohnishi; Morio Arai; Yutaka Yatomi; Yukio Ozaki
Mechanisms of platelet retention in the collagen-coated-bead column.
The Journal of laboratory and clinical medicine 2003;142(4):258-67.
2003: Atsushi Sugiyama; Akira Takahara; Yutaka Yatomi; Yoshioki Satoh; Yuji Nakamura; Keitaro Hashimoto
Constitutional rho-kinase regulates atrioventricular nodal conduction and ventricular repolarization of the canine heart.
Journal of cardiovascular pharmacology 2003;41(6):930-3.
2003: Yi Wu; Naoki Asazuma; Kaneo Satoh; Yutaka Yatomi; Toshiro Takafuta; Michael C Berndt; Yukio Ozaki
Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase.
Blood 2003;101(9):3469-76.
2003: Tsukasa Ohmori; Yutaka Yatomi; Makoto Osada; Fuminori Kazama; Toshiro Takafuta; Hitoshi Ikeda; Yukio Ozaki
Sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2.
Cardiovascular research 2003;58(1):170-7.
2003: Tsutomu Yuminamochi; Yutaka Yatomi; Makoto Osada; Tsukasa Ohmori; Yoshio Ishii; Kumiko Nakazawa; Shigemi Hosogaya; Yukio Ozaki
Expression of the LIM proteins paxillin and Hic-5 in human tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003;51(4):513-21.
2003: Hitoshi Ikeda; Hiroaki Satoh; Mikio Yanase; Yukiko Inoue; Tomoaki Tomiya; Masahiro Arai; Kazuaki Tejima; Kayo Nagashima; Hisato Maekawa; Naoya Yahagi; Yutaka Yatomi; Soutaro Sakurada; Yoh Takuwa; Itsuro Ogata; Satoshi Kimura; Kenji Fujiwara
Antiproliferative property of sphingosine 1-phosphate in rat hepatocytes involves activation of Rho via Edg-5.
Gastroenterology 2003;124(2):459-69.
2003: Ge Rile; Yutaka Yatomi; Toshiro Takafuta; Yukio Ozaki
Ceramide 1-phosphate formation in neutrophils.
Acta haematologica 2003;109(2):76-83.
2002: Makoto Osada; Yutaka Yatomi; Tsukasa Ohmori; Hitoshi Ikeda; Yukio Ozaki
Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist.
Biochemical and biophysical research communications 2002;299(3):483-7.
2002: Tsukasa Ohmori; Yutaka Yatomi
[Platelet disorders].
Rinsho byori. The Japanese journal of clinical pathology 2002;Suppl 123():112-9.
2002: Makoto Osada; Yutaka Yatomi; Tsukasa Ohmori; Shigemi Hosogaya; Yukio Ozaki
Modulation of sphingosine 1-phosphate/EDG signaling by tumor necrosis factor-alpha in vascular endothelial cells.
Thrombosis research 2002;108(2-3):169-74.
2002: Kaneo Satoh; Yutaka Yatomi; Yukio Ozaki
[Detection method for platelet activation markers].
Rinsho byori. The Japanese journal of clinical pathology 2002;50(8):773-8.
2002: Kaneo Satoh; Yutaka Yatomi; Fumio Kubota; Yukio Ozaki
Small aggregates of platelets can be detected sensitively by a flow cytometer equipped with an imaging device: mechanisms of epinephrine-induced aggregation and antiplatelet effects of beraprost.
Cytometry 2002;48(4):194-201.
2002: Takamitsu Sano; Daniel Baker; Tamas Virag; Atsushi Wada; Yutaka Yatomi; Tetsuyuki Kobayashi; Yasuyuki Igarashi; Gabor Tigyi
Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood.
The Journal of biological chemistry 2002;277(24):21197-206.
2002: Norio Hanafusa; Yutaka Yatomi; Koei Yamada; Yuichi Hori; Masaomi Nangaku; Toshihiro Okuda; Toshiro Fujita; Kiyoshi Kurokawa; Masafumi Fukagawa
Sphingosine 1-phosphate stimulates rat mesangial cell proliferation from outside the cells.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(4):580-6.
2002: Atsushi Sugiyama; Yutaka Yatomi; Akira Takahara; Yoshioki Satoh; Keitaro Hashimoto
Cardiac effects of a selective rho-associated kinase inhibitor, Y-27632, assessed in canine isolated, blood-perfused heart preparations.
Japanese journal of pharmacology 2002;88(3):359-61.
2002: Yutaka Yatomi; Tsukasa Ohmori; Makoto Osada; Yukio Ozaki
[Sphingosine 1-phosphate and vascular endothelial cells].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2002;47(4 Suppl):488-95.
2001: Katsue Suzuki-Inoue; Yutaka Yatomi; Naoki Asazuma; M Kainoh; T Tanaka; Kaneo Satoh; Yoshio Ozaki
Rac, a small guanosine triphosphate-binding protein, and p21-activated kinase are activated during platelet spreading on collagen-coated surfaces: roles of integrin alpha(2)beta(1).
Blood 2001;98(13):3708-16.
2001: Tsukasa Ohmori; Yutaka Yatomi; Y Wu; M Osada; Kaneo Satoh; Yoshio Ozaki
Wheat germ agglutinin-induced platelet activation via platelet endothelial cell adhesion molecule-1: involvement of rapid phospholipase C gamma 2 activation by Src family kinases.
Biochemistry 2001;40(43):12992-3001.
2001: Yi Wu; Katsue Suzuki-Inoue; Kaneo Satoh; Naoki Asazuma; Yutaka Yatomi; Michael C Berndt; Yoshio Ozaki
Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling.
Blood 2001;97(12):3836-45.
2001: G Rile; Yutaka Yatomi; R Qi; Kaneo Satoh; Yoshio Ozaki
Potentiation of ibudilast inhibition of platelet aggregation in the presence of endothelial cells.
Thrombosis research 2001;102(3):239-46.
2001: Makoto Osada; Tsukasa Ohmori; Yutaka Yatomi; Kaneo Satoh; S Hosogaya; Yoshio Ozaki
Involvement of Hic-5 in platelet activation: integrin alphaIIbbeta3-dependent tyrosine phosphorylation and association with proline-rich tyrosine kinase 2.
The Biochemical journal 2001;355(Pt 3):691-7.
2001: Yutaka Yatomi; Yoshio Ozaki; Tsukasa Ohmori; Y Igarashi
Sphingosine 1-phosphate: synthesis and release.
Prostaglandins & other lipid mediators 2001;64(1-4):107-22.
2001: Yutaka Yatomi; Yoshio Ozaki
[New laboratory tests for detecting platelet abnormalities].
Rinsho byori. The Japanese journal of clinical pathology 2001;Suppl 115():65-73.
2001: Tsukasa Ohmori; Yutaka Yatomi; H Okamoto; Y Miura; Ge Rile; Kaneo Satoh; Yoshio Ozaki
G(i)-mediated Cas tyrosine phosphorylation in vascular endothelial cells stimulated with sphingosine 1-phosphate: possible involvement in cell motility enhancement in cooperation with Rho-mediated pathways.
The Journal of biological chemistry 2001;276(7):5274-80.
2001: R Qi; Yutaka Yatomi; Yoshio Ozaki
Effects of incubation time, temperature, and anticoagulants on platelet aggregation in whole blood.
Thrombosis research 2001;101(3):139-44.
2001: Katsue Suzuki-Inoue; Yoshio Ozaki; M Kainoh; Y Shin; Yi Wu; Yutaka Yatomi; T Ohmori; T Tanaka; Kaneo Satoh; Takashi Morita
Rhodocytin induces platelet aggregation by interacting with glycoprotein Ia/IIa (GPIa/IIa, Integrin alpha 2beta 1). Involvement of GPIa/IIa-associated src and protein tyrosine phosphorylation.
The Journal of biological chemistry 2001;276(2):1643-52.
2000: Yutaka Yatomi; Tsukasa Ohmori; Ge Rile; F Kazama; H Okamoto; T Sano; Kaneo Satoh; S Kume; G Tigyi; Y Igarashi; Yoshio Ozaki
Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells.
Blood 2000;96(10):3431-8.
2000: R Qi; F Liao; K Inoue; Yutaka Yatomi; K Sato; Yoshio Ozaki
Inhibition by diallyl trisulfide, a garlic component, of intracellular Ca(2+) mobilization without affecting inositol-1,4, 5-trisphosphate (IP(3)) formation in activated platelets.
Biochemical pharmacology 2000;60(10):1475-83.
2000: Hitoshi Ikeda; Yutaka Yatomi; Mikio Yanase; Hitoshi Satoh; Hisato Maekawa; Itsuro Ogata; Yukio Ozaki; Yoh Takuwa; Satoshi Mochida; Kenji Fujiwara
Biological activities of novel lipid mediator sphingosine 1-phosphate in rat hepatic stellate cells.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(2):G304-10.
2000: Yi Wu; Yoshio Ozaki; K Inoue; Kaneo Satoh; T Ohmori; Yutaka Yatomi; K Owadab
Differential activation and redistribution of c-Src and Fyn in platelets, assessed by MoAb specific for C-terminal tyrosine-dephosphorylated c-Src and Fyn.
Biochimica et biophysica acta 2000;1497(1):27-36.
2000: Tsukasa Ohmori; Yutaka Yatomi; K Inoue; Kaneo Satoh; Yoshio Ozaki
Tyrosine dephosphorylation, but not phosphorylation, of p130Cas is dependent on integrin alpha IIb beta 3-mediated aggregation in platelets: implication of p130Cas involvement in pathways unrelated to cytoskeletal reorganization.
Biochemistry 2000;39(19):5797-807.
2000: Kaneo Satoh; Naoki Asazuma; Yutaka Yatomi; Y Fujimura; S Miura; K Titani; Yoshio Ozaki
Activation of protein-tyrosine kinase pathways in human platelets stimulated with the A1 domain of von Willebrand factor.
Platelets 2000;11(3):171-6.
2000: Y Miura; Yutaka Yatomi; Ge Rile; Tsukasa Ohmori; Kaneo Satoh; Yoshio Ozaki
Rho-mediated phosphorylation of focal adhesion kinase and myosin light chain in human endothelial cells stimulated with sphingosine 1-phosphate, a bioactive lysophospholipid released from activated platelets.
Journal of biochemistry 2000;127(5):909-14.
2000: Tsukasa Ohmori; Yutaka Yatomi; Naoki Asazuma; Kaneo Satoh; Yoshio Ozaki
Involvement of proline-rich tyrosine kinase 2 in platelet activation: tyrosine phosphorylation mostly dependent on alphaIIbbeta3 integrin and protein kinase C, translocation to the cytoskeleton and association with Shc through Grb2.
The Biochemical journal 2000;347(Pt 2):561-9.
2000: Atsushi Sugiyama; NN Aye; Yutaka Yatomi; Y Ozaki; Keitaro Hashimoto
Effects of sphingosine 1-phosphate, a naturally occurring biologically active lysophospholipid, on the rat cardiovascular system.
Japanese journal of pharmacology 2000;82(4):338-42.
2000: Atsushi Sugiyama; Yutaka Yatomi; Y Ozaki; Keitaro Hashimoto
Sphingosine 1-phosphate induces sinus tachycardia and coronary vasoconstriction in the canine heart.
Cardiovascular research 2000;46(1):119-25.
2000: T Endo; Yutaka Yatomi; N Amemiya; A Mizoe; M Iino; H Ozawa; Shigemi Hosogaya; Yukio Ozaki
Antibody studies of factor VIII inhibitor in a case with Waldenström's macroglobulinemia.
American journal of hematology 2000;63(3):145-8.
2000: Yoshio Ozaki; R Qi; Kaneo Satoh; Naoki Asazuma; Yutaka Yatomi
Platelet activation mediated through membrane glycoproteins: involvement of tyrosine kinases.
Seminars in thrombosis and hemostasis 2000;26(1):47-51.
1999: Yutaka Yatomi
[Lysophospholipids].
Nihon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():783-5.
1999: L Yang; Yutaka Yatomi; Y Miura; Kaneo Satoh; Yoshio Ozaki
Metabolism and functional effects of sphingolipids in blood cells.
British journal of haematology 1999;107(2):282-93.
1999: R Qi; Yoshio Ozaki; Naoki Asazuma; Kaneo Satoh; Yutaka Yatomi; Che-Leung Law; T Hato; Shosaku Nomura
FcgammaRII tyrosine phosphorylation differs between FcgammaRII cross-linking and platelet-activating anti-platelet monoclonal antibodies.
Biochimica et biophysica acta 1999;1451(2-3):353-63.
1999: L Yang; Yutaka Yatomi; Kaneo Satoh; Y Igarashi; Yoshio Ozaki
Sphingosine 1-phosphate formation and intracellular Ca2+ mobilization in human platelets: evaluation with sphingosine kinase inhibitors.
Journal of biochemistry 1999;126(1):84-9.
1999: Hiroyuki Okamoto; Noriko Takuwa; Yutaka Yatomi; Koichi Gonda; H Shigematsu; Yoh Takuwa
EDG3 is a functional receptor specific for sphingosine 1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16.
Biochemical and biophysical research communications 1999;260(1):203-8.
1999: N Hisano; Yutaka Yatomi; Kaneo Satoh; S Akimoto; Masako Mitsumata; M A Fujino; Yoshio Ozaki
Induction and suppression of endothelial cell apoptosis by sphingolipids: a possible in vitro model for cell-cell interactions between platelets and endothelial cells.
Blood 1999;93(12):4293-9.
1999: L Yang; Yutaka Yatomi; Kaneo Satoh; Yoshio Ozaki
Inhibitory effects of beraprost on platelet aggregation: comparative study utilizing two methods of aggregometry.
Thrombosis research 1999;94(1):25-32.
1999: Tsukasa Ohmori; Yutaka Yatomi; Naoki Asazuma; Kaneo Satoh; Yoshio Ozaki
Suppression of protein kinase C is associated with inhibition of PYK2 tyrosine phosphorylation and enhancement of PYK2 interaction with Src in thrombin-activated platelets.
Thrombosis research 1999;93(6):291-8.
1999: K Inoue; Yoshio Ozaki; Kaneo Satoh; Yi Wu; Yutaka Yatomi; Y Shin; Takashi Morita
Signal transduction pathways mediated by glycoprotein Ia/IIa in human platelets: comparison with those of glycoprotein VI.
Biochemical and biophysical research communications 1999;256(1):114-20.
1999: Koichi Gonda; H Okamoto; Noriko Takuwa; Yutaka Yatomi; Hiroaki Okazaki; T Sakurai; Satoshi Kimura; R Sillard; K Harii; Yoh Takuwa
The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways.
The Biochemical journal 1999;337 ( Pt 1)():67-75.
1998: Yutaka Yatomi; Yoshio Ozaki; Y Igarashi
[Signal transduction related to sphingosine 1-phosphate].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(16 Suppl):2510-5.
1998: H Okamoto; Noriko Takuwa; Koichi Gonda; Hiroaki Okazaki; K Chang; Yutaka Yatomi; H Shigematsu; Yoh Takuwa
EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition.
The Journal of biological chemistry 1998;273(42):27104-10.
1998: Hitoshi Ikeda; Yutaka Yatomi; Mikio Yanase; Hitoshi Satoh; Ayako Nishihara; M Kawabata; Kenji Fujiwara
Effects of lysophosphatidic acid on proliferation of stellate cells and hepatocytes in culture.
Biochemical and biophysical research communications 1998;248(2):436-40.
1998: N Hisano; Yutaka Yatomi; M A Fujino; Y Igarashi; S Kume; Yoshio Ozaki
Quantification of sphingosine derivatives in human platelets: inducible formation of free sphingosine.
Journal of biochemistry 1998;123(2):263-8.
1997: Naoki Asazuma; Yoshio Ozaki; Kaneo Satoh; Yutaka Yatomi; M Handa; Y Fujimura; S Miura; S Kume
Glycoprotein Ib-von Willebrand factor interactions activate tyrosine kinases in human platelets.
Blood 1997;90(12):4789-98.
1997: Yutaka Yatomi; S Yamamura; F Ruan; S Kume; Yoshio Ozaki; Y Igarashi
N,N-dimethylsphingosine 1-phosphate activates human platelets.
FEBS letters 1997;417(3):341-4.
1997: Yutaka Yatomi; Y Igarashi; L Yang; N Hisano; R Qi; Naoki Asazuma; Kaneo Satoh; Yoshio Ozaki; S Kume
Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum.
Journal of biochemistry 1997;121(5):969-73.
1997: Yutaka Yatomi; S Kume
[The measurement of platelet life span].
Nihon rinsho. Japanese journal of clinical medicine 1997;55 Suppl 1():113-6.
1997: Yutaka Yatomi; Yoshio Ozaki; Kaneo Satoh; S Kume; F Ruan; Y Igarashi
N,N-dimethylsphingosine phosphorylation in human platelets.
Biochemical and biophysical research communications 1997;231(3):848-51.
1997: N Amemiya; Yutaka Yatomi; T Endo; A Mizoe; M Yoda-Endo; Tsutomu Yuminamochi; M Yamamoto; Y Matsumoto; Yukio Ozaki; S Kume
A case of hepatocellular carcinoma with marked hyperfibrinogenemia.
Acta haematologica 1997;97(4):236-8.
1996: R Qi; Yoshio Ozaki; K Kuroda; Naoki Asazuma; Yutaka Yatomi; Kaneo Satoh; S Nomura; S Kume
Differential activation of human platelets induced by Fc gamma receptor II cross-linking and by anti-CD9 monoclonal antibody.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(12):5638-45.
1996: L Yang; Yutaka Yatomi; N Hisano; R Qi; Naoki Asazuma; Kaneo Satoh; Y Igarashi; Yoshio Ozaki; S Kume
Activation of protein-tyrosine kinase Syk in human platelets stimulated with lysophosphatidic acid or sphingosine 1-phosphate.
Biochemical and biophysical research communications 1996;229(2):440-4.
1996: Yutaka Yatomi
[Pathogenesis of erythrocyte destruction in autoimmune hemolytic anemia].
Nihon rinsho. Japanese journal of clinical medicine 1996;54(9):2397-401.
1996: Kaneo Satoh; Yoshio Ozaki; Naoki Asazuma; Yutaka Yatomi; Q Ruomei; K Kuroda; L Yang; S Kume
Differential mobilization of tyrosine kinases in human platelets stimulated with thrombin or thrombin receptor agonist peptide.
Biochemical and biophysical research communications 1996;225(3):1084-9.
1996: R Qi; Yoshio Ozaki; Kaneo Satoh; L B Yang; Naoki Asazuma; Yutaka Yatomi; S Kume
Intracellular levels of cyclic AMP and cyclic GMP differentially modify platelet aggregate size in human platelets activated with epinephrine or ADP.
Journal of cardiovascular pharmacology 1996;28(2):215-22.
1996: Naoki Asazuma; Yutaka Yatomi; Yoshio Ozaki; R Qi; K Kuroda; Kaneo Satoh; S Kume
Protein-tyrosine phosphorylation and p72syk activation in human platelets stimulated with collagen is dependent upon glycoprotein Ia/IIa and actin polymerization.
Thrombosis and haemostasis 1996;75(4):648-54.
1996: Kaneo Satoh; Yoshio Ozaki; R Qi; L Yang; Naoki Asazuma; Yutaka Yatomi; S Kume
Factors that affect the size of platelet aggregates in epinephrine-induced activation: a study using the particle counting method based upon light scattering.
Thrombosis research 1996;81(5):515-23.
1996: Yutaka Yatomi; F Ruan; T Megidish; T Toyokuni; S Hakomori; Y Igarashi
N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets.
Biochemistry 1996;35(2):626-33.
1996: R Qi; Yoshio Ozaki; Kaneo Satoh; K Kurota; Naoki Asazuma; Yutaka Yatomi; S Kume
Quantitative measurement of various 5-HT receptor antagonists on platelet activation induced by serotonin.
Thrombosis research 1996;81(1):43-54.
1995: K Kuroda; Yoshio Ozaki; R Qi; Naoki Asazuma; Yutaka Yatomi; Kaneo Satoh; S Nomura; M Suzuki; S Kume
Fc gamma II receptor-mediated platelet activation induced by anti-CD9 monoclonal antibody opens Ca2+ channels which are distinct from those associated with Ca2+ store depletion.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(9):4427-36.
1995: Yutaka Yatomi; Yoshio Ozaki; S Kume
Phosphoinositide metabolism triggered by wheat germ agglutinin in human platelets.
International journal of hematology 1995;62(3):163-73.
1995: Yutaka Yatomi; F Ruan; J Ohta; R J Welch; S Hakomori; Y Igarashi
Quantitative measurement of sphingosine 1-phosphate in biological samples by acylation with radioactive acetic anhydride.
Analytical biochemistry 1995;230(2):315-20.
1995: Yutaka Yatomi; F Ruan; S Hakomori; Y Igarashi
Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets.
Blood 1995;86(1):193-202.
1995: Karin E Bornfeldt; Lee M Graves; Elaine W Raines; Y Igarashi; Gary Wayman; S Yamamura; Yutaka Yatomi; Jaspreet S Sidhu; Edwin G Krebs; S Hakomori
Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction.
The Journal of cell biology 1995;130(1):193-206.
1995: Yoshio Ozaki; Kaneo Satoh; K Kuroda; R Qi; Yutaka Yatomi; S Yanagi; K Sada; H Yamamura; M Yanabu; S Nomura
Anti-CD9 monoclonal antibody activates p72syk in human platelets.
The Journal of biological chemistry 1995;270(25):15119-24.
1995: R Qi; Yoshio Ozaki; Kaneo Satoh; K Kurota; Naoki Asazuma; Yutaka Yatomi; S Kume
Sulphonylurea agents inhibit platelet aggregation and [Ca2+]i elevation induced by arachidonic acid.
Biochemical pharmacology 1995;49(12):1735-9.
1995: Yoshio Ozaki; Kaneo Satoh; Yutaka Yatomi; S Miura; Y Fujimura; S Kume
Protein tyrosine phosphorylation in human platelets induced by interaction between glycoprotein Ib and von Willebrand factor.
Biochimica et biophysica acta 1995;1243(3):482-8.
1995: H Ohta; EA Sweeney; A Masamune; Yutaka Yatomi; S Hakomori; Y Igarashi
Induction of apoptosis by sphingosine in human leukemic HL-60 cells: a possible endogenous modulator of apoptotic DNA fragmentation occurring during phorbol ester-induced differentiation.
Cancer research 1995;55(3):691-7.
1994: H Ohta; Yutaka Yatomi; EA Sweeney; S Hakomori; Y Igarashi
A possible role of sphingosine in induction of apoptosis by tumor necrosis factor-alpha in human neutrophils.
FEBS letters 1994;355(3):267-70.
1994: Kaneo Satoh; Yoshio Ozaki; Yutaka Yatomi; S Kume
Effects of sulfonylurea agents on platelet arachidonic acid metabolism; study on platelet homogenates.
Biochemical pharmacology 1994;48(5):1053-5.
1994: Yutaka Yatomi; Yoshio Ozaki; Kaneo Satoh; S Kume
Synthesis of phosphatidylinositol 3,4-bisphosphate is regulated by protein-tyrosine phosphorylation but the p85 alpha subunit of phosphatidylinositol 3-kinase may not be a target for tyrosine kinases in thrombin-stimulated human platelets.
Biochimica et biophysica acta 1994;1212(3):337-44.
1994: Y Ozaki; K Satoh; Yutaka Yatomi; T Yamamoto; Y Shirasawa; S Kume
Detection of platelet aggregates with a particle counting method using light scattering.
Analytical biochemistry 1994;218(2):284-94.
1994: Y Koike; Yoshio Ozaki; R Qi; Kaneo Satoh; K Kurota; Yutaka Yatomi; S Kume
Phosphatase inhibitors suppress Ca2+ influx induced by receptor-mediated intracellular Ca2+ store depletion in human platelets.
Cell calcium 1994;15(5):381-90.
1994: Yutaka Yatomi; M Higashihara; K Kurokawa; Yoshio Ozaki; S Kume
Effects of the prior activation of protein kinase C on human platelet activation induced by thrombin.
International journal of hematology 1994;59(3):201-9.
1994: K Yasuda; Yutaka Yatomi; T Matsushima; Akiko Yoneyama; Masaaki Higashihara; K Kurokawa; K Nakahara
A case of POEMS syndrome with thrombocytopenia and biliverdinaemia.
British journal of haematology 1994;86(2):389-90.
1993: Yoshio Ozaki; Yutaka Yatomi; Y Jinnai; S Kume
Effects of genistein, a tyrosine kinase inhibitor, on platelet functions. Genistein attenuates thrombin-induced Ca2+ mobilization in human platelets by affecting polyphosphoinositide turnover.
Biochemical pharmacology 1993;46(3):395-403.
1993: Yutaka Yatomi; Yoshio Ozaki; Kaneo Satoh; S Kume
Anti-CD9 monoclonal antibody elicits staurosporine inhibitable phosphatidylinositol 4,5-bisphosphate hydrolysis, phosphatidylinositol 3,4-bisphosphate synthesis, and protein-tyrosine phosphorylation in human platelets.
FEBS letters 1993;322(3):285-90.
1993: Yoshio Ozaki; Y Jinnai; Yutaka Yatomi; M Tawata; T Onaya; S Kume
Effects of dilazep on platelet functions and volume change in patients with diabetes mellitus.
Arzneimittel-Forschung 1993;43(5):536-9.
1993: Yoshio Ozaki; Y Jinnai; Yutaka Yatomi; S Kume
Protein kinase C inhibitors suppress disc-sphere changes of human platelets, as assessed with the shape-change parameter.
European journal of pharmacology 1993;235(2-3):255-65.
1993: Yoshio Ozaki; Kaneo Satoh; Yutaka Yatomi; S Kume
Low concentrations of sodium fluoride inhibit Ca2+ influx induced by receptor-mediated platelet activation.
Biochimica et biophysica acta 1993;1147(1):27-34.
1993: Yutaka Yatomi; Yoshio Ozaki; Y Koike; Kaneo Satoh; S Kume
Wheat germ agglutinin-induced intracellular calcium mobilization in human platelets: suppression by staurosporine and resistance to cyclic AMP inhibition.
Biochemical and biophysical research communications 1993;191(2):453-8.
1992: Yoshio Ozaki; Yutaka Yatomi; S Kume
Effects of oral hypoglycaemic agents on platelet functions.
Biochemical pharmacology 1992;44(4):687-91.
1992: Yutaka Yatomi; Yoshio Ozaki; S Kume
Synthesis of phosphatidylinositol 3,4-bisphosphate but not phosphatidylinositol 3,4,5-trisphosphate is closely correlated with protein-tyrosine phosphorylation in thrombin-activated human platelets.
Biochemical and biophysical research communications 1992;186(3):1480-6.
1992: Yutaka Yatomi; Osamu Hazeki; S Kume; M Ui
Suppression by wortmannin of platelet responses to stimuli due to inhibition of pleckstrin phosphorylation.
The Biochemical journal 1992;285 ( Pt 3)():745-51.
1992: Yutaka Yatomi; Y Arata; S Tada; S Kume; M Ui
Phosphorylation of the inhibitory guanine-nucleotide-binding protein as a possible mechanism of inhibition by protein kinase C of agonist-induced Ca2+ mobilization in human platelet.
European journal of biochemistry / FEBS 1992;205(3):1003-9.
1992: Yoshio Ozaki; Yutaka Yatomi; S Wakasugi; Y Shirasawa; H Saito; S Kume
Thrombin-induced calcium oscillation in human platelets and MEG-01, a megakaryoblastic leukemia cell line.
Biochemical and biophysical research communications 1992;183(2):864-71.
1992: Yoshio Ozaki; Yutaka Yatomi; S Kume
Evaluation of platelet calcium ion mobilization by the use of various divalent ions.
Cell calcium 1992;13(1):19-27.
1991: T Watanabe; Yutaka Yatomi; Shinji Sunaga; I Miki; A Ishii; Akihide Nakao; Masaaki Higashihara; Yousuke Seyama; M Ogura; H Saito
Characterization of prostaglandin and thromboxane receptors expressed on a megakaryoblastic leukemia cell line, MEG-01s.
Blood 1991;78(9):2328-36.
1991: Yoshio Ozaki; Y Jinnai; Yutaka Yatomi; S Kume
Role of sodium ion gradient in facilitating extracellular calcium influx.
Thrombosis research 1991;64(2):179-90.
1991: Yoshio Ozaki; Y Matsumoto; Yutaka Yatomi; M Higashihara; S Kume
Two-step mobilization of arachidonic acid in platelet activation induced by low concentrations of TP 82, a monoclonal antibody against CD9 antigen.
European journal of biochemistry / FEBS 1991;199(2):347-54.
1991: K Moriya; N Miura; Shinji Sunaga; Ryouichi Horie; K Aoki; Yutaka Yatomi; Akiko Yoneyama; Masaaki Higashihara; A Tanabe; K Nakahara
[Acute leukemia successfully treated with natural interferon-alpha].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1991;32(2):170-2.
1990: Yoshio Ozaki; Y Matsumoto; Yutaka Yatomi; M Higashihara; T Kariya; S Kume
Effects of various inhibitors on platelet activation induced by TP 82, a CD 9 monoclonal antibody.
Biochemical pharmacology 1990;40(7):1583-8.
1990: Yutaka Yatomi; Masaaki Higashihara; Y Ozaki; S Kume; Kiyoshi Kurokawa
Intracellular ionized calcium mobilization of CD 9 monoclonal antibody-activated human platelets.
Biochemical and biophysical research communications 1990;171(1):109-15.
1990: Yoshio Ozaki; Y Matsumoto; Yutaka Yatomi; M Higashihara; S Kume
Modification of Na+/H+ exchanger in human platelets by 1,2-dioctanoylglycerol, a protein kinase C activator.
Thrombosis and haemostasis 1990;64(1):165-71.
1990: Yoshio Ozaki; Y Matsumoto; Yutaka Yatomi; M Higashihara; T Kariya; S Kume
Mastoparan, a wasp venom, activates platelets via pertussis toxin-sensitive GTP-binding proteins.
Biochemical and biophysical research communications 1990;170(2):779-85.
1990: Masaaki Higashihara; K Takahata; Yutaka Yatomi; K Nakahara; Kiyoshi Kurokawa
Purification and partial characterization of CD9 antigen of human platelets.
FEBS letters 1990;264(2):270-4.
1990: Yoshio Ozaki; Y Matsumoto; Yutaka Yatomi; M Higashihara; T Kariya; S Kume
Ionomycin, a Ca++ ionophore, increases platelet volume independently of the Na+/H+ exchanger.
Thrombosis research 1990;57(1):87-95.
1989: Yoshio Ozaki; Y Matsumoto; Yutaka Yatomi; M Higashihara; T Kariya; K Shoji
Effects of five anion channel blockers on thrombin- and ionomycin-activated platelet functions.
Biochemical pharmacology 1989;38(13):2147-52.
1988: Tsuyoshi Tange; K Nakahara; Kinuko Mitani; I Yamasaki; H Yasuda; F Tanaka; M Mizuguchi; Hideaki Oda; Yutaka Yatomi; R Takanashi
Establishment of a human megakaryoblastic cell line (T-33) from chronic myelogenous leukemia in megakaryoblastic crisis.
Cancer research 1988;48(21):6137-44.
1987: Yutaka Yatomi; Masaaki Higashihara; A Tanabe; T Ohashi; H Oka; S Kume
Synergism between subthreshold concentrations of thrombin and 12-O-tetradecanoylphorbol 13-acetate in platelet activation.
Biochemical and biophysical research communications 1987;148(3):1025-9.
1987: M Matsushima; Akiko Yoneyama; T Nakamura; Masaaki Higashihara; Yutaka Yatomi; A Tanabe; T Ohashi; H Oka; K Nakahara
A first case of complete remission of beta-interferon sensitive adult T-cell leukemia.
European journal of haematology 1987;39(3):282-7.
1986: Yutaka Yatomi; Masaaki Higashihara; A Tanabe; T Ohashi; K Takahata; T Kariya; S Kume
Separable function of platelet release reaction and clot retraction.
Biochemical and biophysical research communications 1986;140(1):329-34.
1985: Masaaki Higashihara; H Maeda; Yutaka Yatomi; K Takahata; H Oka; S Kume
The platelet protein phosphorylation induced by a monoclonal antibody against human platelets (TP82).
Biochemical and biophysical research communications 1985;133(1):306-13.