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Randall Yatscoff
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22
Legatt, Donald
8
Aspeslet, Launa
7
Kneteman, Norman
6
Trepanier, Daniel
5
Rajotte, Ray
5
Koshal, Arvind
5
Lakey, Jonathan
5
Freitag, Derrick
4
Gallant, Heather
4
Shapiro, James
3
Rush, David
3
Halloran, Philip
3
Audette, RJ
3
Fedorak, Richard
3
Jeffery, John
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All Publications
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2008: Gupta Aditya K; Langley Richard G; Lynde Charles; Barber Kirk; Gulliver Wayne; Lauzon Gilles; Aspeslet Launa J; Foster Robert T; Huizinga Robert B; Yatscoff Randall W
ISA247: quality of life results from a phase II, randomized, placebo-controlled study.
Journal of cutaneous medicine and surgery 2008;12(6):268-75.
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2006: Bissonnette Robert; Papp Kim; Poulin Yves; Lauzon Gilles; Aspeslet Launa; Huizinga Robert; Mayo Patrick; Foster Robert T; Yatscoff Randall W; Maksymowych Walter P;
A randomized, multicenter, double-blind, placebo-controlled phase 2 trial of ISA247 in patients with chronic plaque psoriasis.
Journal of the American Academy of Dermatology 2006;54(3):472-8.
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2005: Bîrsan Tudor; Dambrin Camille; Freitag Derrick G; Yatscoff Randall W; Morris Randall E
The novel calcineurin inhibitor ISA247: a more potent immunosuppressant than cyclosporine in vitro.
Transplant international : official journal of the European Society for Organ Transplantation 2005;17(12):767-71.
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2005: Shapiro A M James; Gallant Heather L; Hao Er Geng; Lakey Jonathan R T; McCready Tara; Rajotte Ray V; Yatscoff Randall W; Kneteman Norman M
The portal immunosuppressive storm: relevance to islet transplantation?
Therapeutic drug monitoring 2005;27(1):35-7.
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2002: Maksymowych Walter P; Jhangri Gian S; Aspeslet Launa; Abel Mark D; Trepanier Daniel J; Naicker Selvaraj; Freitag Derrick G; Cooper Bobbi-Lynn; Foster Robert T; Yatscoff Randall W
Amelioration of accelerated collagen induced arthritis by a novel calcineurin inhibitor, ISA(TX)247.
The Journal of rheumatology 2002;29(8):1646-52.
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2001: Aspeslet L; Freitag D; Trepanier D; Abel M; Naicker S; Kneteman N; Foster R; Yatscoff R
ISA(TX)247: a novel calcineurin inhibitor.
Transplantation proceedings 2001;33(1-2):1048-51.
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2000: Gallant-Haidner H L; Trepanier D J; Freitag D G; Yatscoff R W
Pharmacokinetics and metabolism of sirolimus.
Therapeutic drug monitoring 2000;22(1):31-5.
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2000: Aspeslet L J; Yatscoff R W
Requirements for therapeutic drug monitoring of sirolimus, an immunosuppressive agent used in renal transplantation.
Clinical therapeutics 2000;22 Suppl B():B86-92.
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1999: Pluhator-Murton M M; Fedorak R N; Audette R J; Marriage B J; Yatscoff R W; Gramlich L M
Trace element contamination of total parenteral nutrition. 2. Effect of storage duration and temperature.
JPEN. Journal of parenteral and enteral nutrition 1999;23(4):228-32.
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1999: Pluhator-Murton M M; Fedorak R N; Audette R J; Marriage B J; Yatscoff R W; Gramlich L M
Trace element contamination of total parenteral nutrition. 1. Contribution of component solutions.
JPEN. Journal of parenteral and enteral nutrition 1999;23(4):222-7.
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1999: Trepanier D J; Abel M D; Freitag D G; Yatscoff R W
Study of FK-binding protein: FK506-metabolite complexes by electrospray mass spectrometry: correlation to immunosuppressive activity.
Therapeutic drug monitoring 1999;21(3):274-80.
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1999: Mock T; Yatscoff R; Foster R; Hyun J H; Chung I S; Shim C S; Yacyshyn B
Clinical validation of the Helikit: a 13C urea breath test used for the diagnosis of Helicobacter pylori infection.
Clinical biochemistry 1999;32(1):59-63.
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1998: Dias V C; Madsen K L; Mulder K E; Keelan M; Yatscoff R W; Thomson A B
Oral administration of rapamycin and cyclosporine differentially alter intestinal function in rabbits.
Digestive diseases and sciences 1998;43(10):2227-36.
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1998: Yatscoff R W; Aspeslet L J
The monitoring of immunosuppressive drugs: a pharmacodynamic approach.
Therapeutic drug monitoring 1998;20(5):459-63.
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1998: Ye L; Le X C; Xing J Z; Ma M; Yatscoff R
Competitive immunoassay for cyclosporine using capillary electrophoresis with laser induced fluorescence polarization detection.
Journal of chromatography. B, Biomedical sciences and applications 1998;714(1):59-67.
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1998: Trepanier D J; Gallant H; Legatt D F; Yatscoff R W
Rapamycin: distribution, pharmacokinetics and therapeutic range investigations: an update.
Clinical biochemistry 1998;31(5):345-51.
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1998: Pilarski L M; Yatscoff R W; Murphy G F; Belch A R
Drug resistance in multiple myeloma: cyclosporin A analogues and their metabolites as potential chemosensitizers.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(4):505-9.
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1998: Shapiro A M; Gallant H; Hao E; Wong J; Rajotte R; Yatscoff R; Kneteman N
Portal vein immunosuppressant levels and islet graft toxicity.
Transplantation proceedings 1998;30(2):641.
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1998: Yatscoff R W; Aspeslet L J; Gallant H L
Pharmacodynamic monitoring of immunosuppressive drugs.
Clinical chemistry 1998;44(2):428-32.
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1997: Jortani S A; Trepanier D; Yatscoff R W; Valdes R
Convergence of three methods to resolve discrepant immunoassay digitoxin results.
Clinical chemistry 1997;43(9):1805-8.
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1997: Langman L J; Nakakura H; Thliveris J A; LeGatt D F; Yatscoff R W
Pharmacodynamic monitoring of mycophenolic acid in rabbit heterotopic heart transplant model.
Therapeutic drug monitoring 1997;19(2):146-52.
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1997: Dias V C; Legatt D F; Yatscoff R W
The EMIT Cyclosporine Assay: development of application protocols for the Boehringer Mannheim Hitachi 911 and 917 analyzers.
Clinical biochemistry 1997;30(2):155-62.
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1997: Aspeslet L J; LeGatt D F; Murphy G; Yatscoff R W
Effect of assay methodology on pharmacokinetic differences between cyclosporine Neoral and Sandimmune formulations.
Clinical chemistry 1997;43(1):104-8.
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1996: Gallant H L; Yatscoff R W
P70 S6 kinase assay: a pharmacodynamic monitoring strategy for rapamycin; assay development.
Transplantation proceedings 1996;28(6):3058-61.
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1996: Yatscoff R W; Langman L J; LeGatt D F
Pharmacodynamic monitoring of immunosuppressive drugs.
Transplantation proceedings 1996;28(6):3013-5.
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1996: Pluhator-Murton M M; Fedorak R N; Audette R J; Marriage B J; Yatscoff R W
Extent of trace-element contamination from simulated compounding of total parenteral nutrient solutions.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 1996;53(19):2299-303.
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1996: Langman L J; LeGatt D F; Halloran P F; Yatscoff R W
Pharmacodynamic assessment of mycophenolic acid-induced immunosuppression in renal transplant recipients.
Transplantation 1996;62(5):666-72.
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1996: Yatscoff R W; Chapelsky L; Morrish D
Analytical and clinical evaluation of an automated cortisol assay on the ACS:180.
Clinical biochemistry 1996;29(4):315-9.
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1996: Dias V C; Moschopedis T; Prosser C; Yatscoff R W
Evaluation of the CLINITEK ATLAS for routine macroscopic urinalysis.
Clinical biochemistry 1996;29(3):217-23.
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1996: Batiuk T D; Urmson J; Vincent D; Yatscoff R W; Halloran P F
Quantitating immunosuppression. Estimating the 50% inhibitory concentration for in vivo cyclosporine in mice.
Transplantation 1996;61(11):1618-24.
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1996: Fryer J P; Pascoe E A; Yatscoff R W; Thliveris J A
A comparison of cyclosporine A and cyclosporine G in a rabbit heterotopic cardiac transplant model: graft outcome and histological findings.
Histology and histopathology 1996;11(2):277-84.
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1996: Yatscoff R W
Pharmacokinetics of rapamycin.
Transplantation proceedings 1996;28(2):970-3.
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1996: Langman L J; Shapiro A M; Lakey J R; LeGatt D F; Kneteman N M; Yatscoff R W
Pharmacodynamic assessment of mycophenolic acid in a canine model.
Transplantation proceedings 1996;28(2):934-6.
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1996: Korbutt G S; Aspeslet L; Ao Z; Warnock G L; Ezekowitz J; Koshal A; Rajotte R V; Yatscoff R W
Porcine islet cell antigens are recognized by xenoreactive natural human antibodies of both IgG and IgM subtypes.
Transplantation proceedings 1996;28(2):837-8.
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1996: Lakey J R; Yatscoff R W; Koshal A; Rajotte R V
Prolongation of concordant islet xenografts with leflunomide.
Transplantation proceedings 1996;28(2):816.
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1996: Lucien J; Marath A; Rayat G; Thliveris J; Koshal A; Yatscoff R
Efficacy of leflunomide to reduce xenoantibody titers in vivo: an evaluation of the prolongation of discordant xenograft survival.
Transplantation proceedings 1996;28(2):704-7.
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1996: Dias V C; Yatscoff R W
An in vitro method for predicting in vivo oral bioavailability of novel immunosuppressive drugs.
Clinical biochemistry 1996;29(1):43-9.
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1996: Langman L J; Shapiro A M; Lakey J R; LeGatt D F; Kneteman N M; Yatscoff R W
Pharmacodynamic assessment of mycophenolic acid-induced immunosuppression by measurement of inosine monophosphate dehydrogenase activity in a canine model.
Transplantation 1996;61(1):87-92.
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1995: Yatscoff R W; Boeckx R; Holt D W; Kahan B D; LeGatt D F; Sehgal S; Soldin S J; Napoli K; Stiller C
Consensus guidelines for therapeutic drug monitoring of rapamycin: report of the consensus panel.
Therapeutic drug monitoring 1995;17(6):676-80.
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1995: Yatscoff R W; Wang P; Chan K; Hicks D; Zimmerman J
Rapamycin: distribution, pharmacokinetics, and therapeutic range investigations.
Therapeutic drug monitoring 1995;17(6):666-71.
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1995: Yatscoff R W; Langman L; LeGatt D F
Therapeutic drug monitoring of cyclosporin G.
Therapeutic drug monitoring 1995;17(6):655-9.
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1995: Lucien J; Dias V C; LeGatt D F; Yatscoff R W
Blood distribution and single-dose pharmacokinetics of leflunomide.
Therapeutic drug monitoring 1995;17(5):454-9.
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1995: Yatscoff R W; Chackowsky P
Quality assurance program for cyclosporin G (OG37-325).
Therapeutic drug monitoring 1995;17(4):342-7.
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1995: van Wijngaarden M; Mock T; Dinwoodie A; LeGatt D; Yatscoff R
Coma and metabolic acidosis related to the use of muscle liniment.
Critical care medicine 1995;23(6):1143-5.
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1995: Mock T; Morrison D; Yatscoff R
Evaluation of the i-STAT system: a portable chemistry analyzer for the measurement of sodium, potassium, chloride, urea, glucose, and hematocrit.
Clinical biochemistry 1995;28(2):187-92.
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1995: Thliveris J A; Solez K; Yatscoff R W
A comparison of the effects of rapamycin and cyclosporine on kidney and heart morphology in a rabbit heterotopic heart transplant model.
Histology and histopathology 1995;10(2):417-21.
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1995: Langman L J; LeGatt D F; Yatscoff R W
Pharmacodynamic assessment of mycophenolic acid-induced immunosuppression by measuring IMP dehydrogenase activity.
Clinical chemistry 1995;41(2):295-9.
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1995: Thliveris J A; Yatscoff R W
Effect of rapamycin on morphological and functional parameters in the kidney of the rabbit.
Transplantation 1995;59(3):427-9.
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1995: Dias V C; Lucien J; LeGatt D F; Yatscoff R W
Measurement of the active leflunomide metabolite (A77 1726) by reverse-phase high-performance liquid chromatography.
Therapeutic drug monitoring 1995;17(1):84-8.
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1994: Dias V C; Madsen K L; Yatscoff R W; Doring K; Thomson A B
Orally administered immunosuppressants modify intestinal uptake of nutrients in rabbits.
Transplantation 1994;58(11):1241-6.
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1994: Langman L J; LeGatt D F; Yatscoff R W
Blood distribution of mycophenolic acid.
Therapeutic drug monitoring 1994;16(6):602-7.
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1994: Yatscoff R W
Laboratory support for transplantation.
Clinical chemistry 1994;40(11 Pt 2):2166-73.
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1994: Langman L J; Yatscoff R W
The effect of cyclosporine G (OG37-325), cyclosporine A, and their metabolites on the release of vasoactive substances from primary renal cell lines.
Transplantation proceedings 1994;26(5):3002-5.
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1994: Batiuk T D; Yatscoff R W; Halloran P F
What is the dose-response curve for the effects of cyclosporine on calcineurin and cytokine induction in vivo?
Transplantation proceedings 1994;26(5):2835-6.
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1994: LeGatt D F; Chooi M; Simpson A I; Yatscoff R W
Application of the EMIT cyclosporine assay to the Technicon Axon System.
Transplantation proceedings 1994;26(5):2811-3.
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1994: LeGatt D F; Chooi M; Simpson A I; Yatscoff R W
EMIT cyclosporine assay: development of an application protocol for Technicon AXON System.
Clinical biochemistry 1994;27(5):387-94.
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1994: Langman L J; Yatscoff R W
Comparison of the effects of cyclosporin G (OG37-325), cyclosporin A, and their metabolites on the release of endothelin and prostacyclin from primary renal and aortic endothelial cell lines.
Therapeutic drug monitoring 1994;16(5):450-7.
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1994: Yatscoff R W; Wang S; Keenan R; Chackowsky P; Lowes N; Koshal A
Efficacy of rapamycin, RS-61443 and cyclophosphamide in the prolongation of survival of discordant pig to rabbit cardiac xenografts.
The Canadian journal of cardiology 1994;10(7):711-6.
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1994: Coates J E; Chapelsky L J; Yatscoff R W
Pediatric reference intervals for plasma renin.
Clinical biochemistry 1994;27(4):316-7.
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1994: Yatscoff R W; Wang S; Keenan R; Chackowsky P; Koshal A
Efficacy of rapamycin, RS-61443, and cyclophosphamide in the prolongation of survival of discordant pig-to-rabbit cardiac xenografts.
Transplantation proceedings 1994;26(3):1271-3.
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1994: Langman L J; Leichtman A B; Weitzel W F; Yatscoff R W
Steady-state concentration of cyclosporin G (OG37-325) and its metabolites in renal transplant recipients.
Clinical chemistry 1994;40(4):613-6.
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1994: Thliveris J A; Yatscoff R W; Mihatsch M J
Chronic cyclosporine-induced nephrotoxicity: a rabbit model.
Transplantation 1994;57(5):774-6.
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1994: Dembinski T C; Yatscoff R W; Blandford D E
Thyrotoxicosis and hungry bone syndrome--a cause of posttreatment hypocalcemia.
Clinical biochemistry 1994;27(1):69-74.
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1994: LeGatt D F; Coates J E; Simpson A I; Shalapay C E; Rintoul B J; Yatscoff R W
A comparison of cyclosporine assays using sequential samples from selected transplant patients.
Clinical biochemistry 1994;27(1):43-8.
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1994: Dias V C; Yatscoff R W
Investigation of rapamycin transport and uptake across absorptive human intestinal cell monolayers.
Clinical biochemistry 1994;27(1):31-6.
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1993: Yakimets W J; Lakey J R; Yatscoff R W; Katyal D; Ao Z; Finegood D T; Rajotte R V; Kneteman N M
Prolongation of canine pancreatic islet allograft survival with combined rapamycin and cyclosporine therapy at low doses. Rapamycin efficacy is blood level related.
Transplantation 1993;56(6):1293-8.
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1993: Yatscoff R W; LeGatt D F; Kneteman N M
Therapeutic monitoring of rapamycin: a new immunosuppressive drug.
Therapeutic drug monitoring 1993;15(6):478-82.
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1993: Yatscoff R; LeGatt D; Keenan R; Chackowsky P
Blood distribution of rapamycin.
Transplantation 1993;56(5):1202-6.
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1993: Yatscoff R W; Keenan R; LeGatt D F
Single-dose pharmacokinetics of the new immunosuppressant RS-61443 in the rabbit.
Therapeutic drug monitoring 1993;15(5):400-4.
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1993: Yatscoff R W; Fryer J; Thliveris J A
Comparison of the effect of rapamycin and FK506 on release of prostacyclin and endothelin in vitro.
Clinical biochemistry 1993;26(5):409-14.
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1993: Yatscoff R W; Langman L J; LeGatt D F
Cross-reactivities of cyclosporin G (NVa2 cyclosporin) and metabolites in cyclosporin A immunoassays.
Clinical chemistry 1993;39(6):1089-92.
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1993: Rayat G; Yatscoff R; Silverman R; McKenna R
A comparison of the immunosuppressive effects of cyclosporine A and cyclosporine G in vivo and in vitro.
Transplantation 1993;55(3):623-6.
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1993: Fryer J; Yatscoff R W; Pascoe E A; Thliveris J
The relationship of blood concentrations of rapamycin and cyclosporine to suppression of allograft rejection in a rabbit heterotopic heart transplant model.
Transplantation 1993;55(2):340-5.
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1993: Yatscoff R W; Honcharik N; Lukowski M; Thliveris J; Chackowsky P; Faraci C
Distribution of cyclosporin G (NVa2 cyclosporin) in blood and plasma.
Clinical chemistry 1993;39(2):213-7.
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1992: Honcharik N; Fryer J; Yatscoff R
Pharmacokinetics of rapamycin: single-dose studies in the rabbit.
Therapeutic drug monitoring 1992;14(6):475-8.
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1992: Yatscoff R W; Faraci C; Bolingbroke P
Measurement of rapamycin in whole blood using reverse-phase high-performance liquid chromatography.
Therapeutic drug monitoring 1992;14(2):138-41.
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1992: Copeland K R; Yatscoff R W
Comparison of the effects of cyclosporine and its metabolites on the release of prostacyclin and endothelin from mesangial cells.
Transplantation 1992;53(3):640-5.
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1991: Honcharik N; Yatscoff R W; Jeffery J R; Rush D N
The effect of meal composition on cyclosporine absorption.
Transplantation 1991;52(6):1087-9.
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1991: Copeland K R; Yatscoff R W
The isolation, structural characterization, and immunosuppressive activity of cyclosporin G (NVa2-cyclosporine) metabolites.
Therapeutic drug monitoring 1991;13(4):281-8.
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1991: Thliveris J A; Yatscoff R W; Lukowski M P; Copeland K R
Cyclosporine nephrotoxicity--experimental models.
Clinical biochemistry 1991;24(1):93-5.
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1991: Yatscoff R W; Rosano T G; Bowers L D
The clinical significance of cyclosporine metabolites.
Clinical biochemistry 1991;24(1):23-35.
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1991: Thliveris J A; Yatscoff R W; Lukowski M P; Copeland K R; Jeffery J R; Murphy G F
Chronic ciclosporin nephrotoxicity: a rabbit model.
Nephron 1991;57(4):470-6.
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1990: Copeland K R; Thliveris J A; Yatscoff R W
Toxicity of cyclosporine metabolites.
Therapeutic drug monitoring 1990;12(6):525-32.
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1990: Yatscoff R W; Copeland K R; Faraci C J
Abbott TDx monoclonal antibody assay evaluated for measuring cyclosporine in whole blood.
Clinical chemistry 1990;36(11):1969-73.
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1990: Copeland K R; Yatscoff R W
Immunosuppressive activity and toxicity of cyclosporine metabolites characterized by mass spectroscopy and nuclear magnetic resonance.
Transplantation proceedings 1990;22(3):1146-9.
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1990: Copeland K; Lukowski M; Yatscoff R; Thliveris J; Honcharik N
Pharmacokinetics and biotransformation of the cyclosporine metabolite M-17 in the rabbit.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(2):226-30.
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1990: Copeland K R; Yatscoff R W; McKenna R M
Immunosuppressive activity of cyclosporine metabolites compared and characterized by mass spectroscopy and nuclear magnetic resonance.
Clinical chemistry 1990;36(2):225-9.
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1990: Copeland K R; Yatscoff R W; Mehta A E; Thliveris J A
Chronic hyperglycemia in experimental diabetes mellitus of short duration does not contribute to muscle capillary basement membrane thickening.
Acta anatomica 1990;138(4):285-92.
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1989: Copeland K R; Yatscoff R W; Jeffery J; Rush D
Longitudinal monitoring of cyclosporine using a radioimmunoassay specific for the parent drug.
Transplantation 1989;47(5):899-902.
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1989: Copeland K R; Yatscoff R W; Thliveris J A; Penner S B; Mehta A
Effect of a low protein diet on the relationship of nonenzymatic glycation to altered renal structure and function in diabetes mellitus.
The Journal of diabetic complications 1989;3(2):113-9.
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1989: Copeland K R; Yatscoff R W; Rush D; Jeffery J R
Comparison of the in vitro immunosuppressive effects of cyclosporine A and its metabolites.
Transplantation proceedings 1989;21(1 Pt 2):1449-52.
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1988: Copeland K R; Yatscoff R W
Use of a monoclonal antibody for the therapeutic monitoring of cyclosporine in plasma and whole blood.
Therapeutic drug monitoring 1988;10(4):453-8.
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1987: Copeland K R; Yatscoff R W; Thliveris J A; Mehta A; Penner B
Non-enzymatic glycation and altered renal structure and function in the diabetic rat.
Kidney international 1987;32(5):664-70.
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1987: Yatscoff R W; Mehta A; Gerrard J M; Thliveris J
Glycation of platelet protein in diabetes mellitus: lack of correlation with platelet function.
Clinical biochemistry 1987;20(5):359-63.
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1987: Yatscoff R W
Evaluation of cyclosporine kit utilizing an iodinated tracer and double antibody precipitation.
Clinical biochemistry 1987;20(3):191-5.
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