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Yoshio Yazaki

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Yasushi Kaburagi; Ryo Yamashita; Yuzuru Ito; Hitoshi Okochi; Ritsuko Yamamoto-Honda; Kazuki Yasuda; Hisahiko Sekihara; Takehiko Sasazuki; Takashi Kadowaki; Yoshio Yazaki
Insulin-induced cell cycle progression is impaired in chinese hamster ovary cells overexpressing insulin receptor substrate-3.
Doubun Hayashi; Sumiyo Kudoh; Ichiro Shiojima; Yunzeng Zou; Koichiro Harada; Masaki Shimoyama; Yasushi Imai; Koshiro Monzen; Tsutomu Yamazaki; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Atrial natriuretic peptide inhibits cardiomyocyte hypertrophy through mitogen-activated protein kinase phosphatase-1.
Toshio Nagai; Mariko Tanaka-Ishikawa; Ryuichi Aikawa; Hisamitsu Ishihara; Weidung Zhu; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Cdc42 plays a critical role in assembly of sarcomere units in series of cardiac myocytes.

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All Publications

2004: Yasushi Kaburagi; Ryo Yamashita; Yuzuru Ito; Hitoshi Okochi; Ritsuko Yamamoto-Honda; Kazuki Yasuda; Hisahiko Sekihara; Takehiko Sasazuki; Takashi Kadowaki; Yoshio Yazaki
Insulin-induced cell cycle progression is impaired in chinese hamster ovary cells overexpressing insulin receptor substrate-3.
Endocrinology 2004;145(12):5862-74.
2004: Doubun Hayashi; Sumiyo Kudoh; Ichiro Shiojima; Yunzeng Zou; Koichiro Harada; Masaki Shimoyama; Yasushi Imai; Koshiro Monzen; Tsutomu Yamazaki; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Atrial natriuretic peptide inhibits cardiomyocyte hypertrophy through mitogen-activated protein kinase phosphatase-1.
Biochemical and biophysical research communications 2004;322(1):310-9.
2003: Toshio Nagai; Mariko Tanaka-Ishikawa; Ryuichi Aikawa; Hisamitsu Ishihara; Weidung Zhu; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Cdc42 plays a critical role in assembly of sarcomere units in series of cardiac myocytes.
Biochemical and biophysical research communications 2003;305(4):806-10.
2003: Tomohiro Harada; Hiroyuki Morita; Yasushi Imai; Doubun Hayashi; Norihiko Takeda; Koji Maemura; Yoshio Yazaki; Ryozo Nagai
Deficiency of protein S-mediated familial venous thrombophilia--a case report.
Angiology 2003;54(3):377-81.
2003: Yasushi Kaburagi; Shinobu Satoh; Ritsuko Yamamoto-Honda; Yuzuru Ito; Yasuo Akanuma; Hisahiko Sekihara; Kazuki Yasuda; Takehiko Sasazuki; Takashi Kadowaki; Yoshio Yazaki
Protection of insulin receptor substrate-3 from staurosporine-induced apoptosis.
Biochemical and biophysical research communications 2003;300(2):371-7.
2002: Yasushi Imai; Takayuki Shindo; Koji Maemura; Masataka Sata; Yuichiro Saito; Yukiko Kurihara; Masahiro Akishita; Jun-ichi Osuga; Shun Ishibashi; Kazuyuki Tobe; Hiroyuki Morita; Yoshio Oh-hashi; Toru Suzuki; Hiromitsu Maekawa; Kenji Kangawa; Naoto Minamino; Yoshio Yazaki; Ryozo Nagai; Hiroki Kurihara
Resistance to neointimal hyperplasia and fatty streak formation in mice with adrenomedullin overexpression.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(8):1310-5.
2002: Ryuichi Aikawa; Yuko Nitta-Komatsubara; Sumiyo Kudoh; Hiroyuki Takano; Toshio Nagai; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Reactive oxygen species induce cardiomyocyte apoptosis partly through TNF-alpha.
Cytokine 2002;18(4):179-83.
2002: Takayuki Shindo; Hiroki Kurihara; Koji Maemura; Yukiko Kurihara; Otoya Ueda; Hiramitsu Suzuki; Tomoyuki Kuwaki; Kihwan Ju; Y Wang; Aya Ebihara; Hiroaki Nishimatsu; Nobuo Moriyama; M Fukuda; Y Akimoto; H Hirano; Hiroyuki Morita; Mamoru Kumada; Yoshio Yazaki; Ryozo Nagai; K Kimura
Renal damage and salt-dependent hypertension in aged transgenic mice overexpressing endothelin-1.
Journal of molecular medicine (Berlin, Germany) 2002;80(2):105-16.
2002: Kazuo Hara; Philippe Boutin; Yasumichi Mori; Kazuyuki Tobe; Christian Dina; Kazuki Yasuda; Toshimasa Yamauchi; Shuichi Otabe; Terumasa Okada; Kazuhiro Eto; Hiroko Kadowaki; Ryoko Hagura; Yasuo Akanuma; Yoshio Yazaki; Ryozo Nagai; Matsuo Taniyama; Koichi Matsubara; Madoka Yoda; Yasuko Nakano; Motowo Tomita; Satoshi Kimura; Chikako Ito; philippe froguel; Takashi Kadowaki
Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population.
Diabetes 2002;51(2):536-40.
2001: Yoshio Oh-hashi; Takayuki Shindo; Yukiko Kurihara; Takasuke Imai; Yuhui Wang; Hiroyuki Morita; Yasushi Imai; Yuji Kayaba; Hiroaki Nishimatsu; Y Suematsu; Yasunobu Hirata; Yoshio Yazaki; Ryozo Nagai; Tomoyuki Kuwaki; Hiroki Kurihara
Elevated sympathetic nervous activity in mice deficient in alphaCGRP.
Circulation research 2001;89(11):983-90.
2001: Takayuki Shindo; Yukiko Kurihara; Hiroaki Nishimatsu; Nobuo Moriyama; Masao Kakoki; Y Wang; Yasuharu Imai; Aya Ebihara; Tomoyuki Kuwaki; Kihwan Ju; Naoto Minamino; Kenji Kangawa; T Ishikawa; M Fukuda; Y Akimoto; H Kawakami; T Imai; Hiroyuki Morita; Yoshio Yazaki; Ryozo Nagai; Yasunobu Hirata; Hiroki Kurihara
Vascular abnormalities and elevated blood pressure in mice lacking adrenomedullin gene.
Circulation 2001;104(16):1964-71.
2001: Toru Hosoda; Koshiro Monzen; Yukio Hiroi; Toru Oka; Eiki Takimoto; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
A novel myocyte-specific gene Midori promotes the differentiation of P19CL6 cells into cardiomyocytes.
The Journal of biological chemistry 2001;276(38):35978-89.
2001: Yasunobu Hirata; A Matsumoto; T Aoyagi; K Yamaoki; Issei Komuro; Takahiro Suzuki; T Ashida; T Sugiyama; Yusuke Hada; Iwao Kuwajima; M Nishinaga; H Akioka; O Nakajima; Ryozo Nagai; Yoshio Yazaki
Measurement of plasma brain natriuretic peptide level as a guide for cardiac overload.
Cardiovascular research 2001;51(3):585-91.
2001: Takahiro Suzuki; T Yamazaki; Yoshio Yazaki
The role of the natriuretic peptides in the cardiovascular system.
Cardiovascular research 2001;51(3):489-94.
2001: Yunzeng Zou; A Yao; Weidong Zhu; Sumiyo Kudoh; Yukio Hiroi; Masaki Shimoyama; Hiroki Uozumi; Osami Kohmoto; Tokiharu Takahashi; Futoshi Shibasaki; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
Isoproterenol activates extracellular signal-regulated protein kinases in cardiomyocytes through calcineurin.
Circulation 2001;104(1):102-8.
2001: Yunzeng Zou; Yukio Hiroi; Hiroki Uozumi; Eiki Takimoto; Haruhiro Toko; Weidong Zhu; Sumiyo Kudoh; Miho Mizukami; Masaki Shimoyama; Futoshi Shibasaki; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
Calcineurin plays a critical role in the development of pressure overload-induced cardiac hypertrophy.
Circulation 2001;104(1):97-101.
2001: Y Gu; Yunzeng Zou; Ryuichi Aikawa; Doubun Hayashi; Sumiyo Kudoh; Toshimasa Yamauchi; Hiroki Uozumi; Weidong Zhu; Takashi Kadowaki; Yoshio Yazaki; Issei Komuro
Growth hormone signalling and apoptosis in neonatal rat cardiomyocytes.
Molecular and cellular biochemistry 2001;223(1-2):35-46.
2001: Yukio Hiroi; Junya Hiroi; Sumiyo Kudoh; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Two distinct mechanisms of angiotensin II-induced negative regulation of the mitogen-activated protein kinases in cultured cardiac myocytes.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(4):385-94.
2001: Yukio Hiroi; S Kudoh; Koshiro Monzen; Y Ikeda; Yoshio Yazaki; Ryozo Nagai; I Komuro
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation.
Nature genetics 2001;28(3):276-80.
2001: Hiroki Uozumi; Yukio Hiroi; Yunzeng Zou; Eiki Takimoto; Haruhiro Toko; Pei Niu; Masaki Shimoyama; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
gp130 plays a critical role in pressure overload-induced cardiac hypertrophy.
The Journal of biological chemistry 2001;276(25):23115-9.
2001: Koshiro Monzen; Yukio Hiroi; Sumiyo Kudoh; Hiroshi Akazawa; Toru Oka; Eiki Takimoto; Doubun Hayashi; Toru Hosoda; M Kawabata; Kohei Miyazono; S Ishii; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation.
The Journal of cell biology 2001;153(4):687-98.
2001: Masaki Shimoyama; Doubun Hayashi; Yunzeng Zou; Eiki Takimoto; Miho Mizukami; Koshiro Monzen; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
[Calcineurin inhibitor attenuates the development and induces the regression of cardiac hypertrophy in rats with salt-sensitive hypertension].
Journal of cardiology 2001;37(2):114-8.
2001: Hiroyuki Morita; Hiroki Kurihara; S Yoshida; Yuichiro Saito; Takayuki Shindo; Yoshio Oh-hashi; Yukiko Kurihara; Yoshio Yazaki; Ryozo Nagai
Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury.
Circulation 2001;103(1):133-9.
2001: T Itoh; K Kikuchi; Y Odagawa; S Takata; K Yano; S Okada; N Haneda; Seishi Ogawa; O Nakano; Y Kawahara; H Kasai; T Nakayama; T Fukutomi; Harumizu Sakurada; A Shimizu; Yoshio Yazaki; Ryozo Nagai; Yusuke Nakamura; Toshihiro Tanaka
Correlation of genetic etiology with response to beta-adrenergic blockade among symptomatic patients with familial long-QT syndrome.
Journal of human genetics 2001;46(1):38-40.
2000: Koji Wakimoto; Kinji Kobayashi; Makoto Kuro-o; Atsushi Yao; Takahiro Iwamoto; Noriyuki Yanaka; Satomi Kita; A Nishida; S Azuma; Y Toyoda; Kenji Omori; H Imahie; T Oka; Sumiyo Kudoh; Osami Kohmoto; Yoshio Yazaki; Munekazu Shigekawa; Yuji Imai; Yo ichi Nabeshima; Issei Komuro
Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat.
The Journal of biological chemistry 2000;275(47):36991-8.
2000: Weidong Zhu; Ichiro Shiojima; Yukio Hiroi; Yunzeng Zou; Hiroshi Akazawa; Miho Mizukami; Haruhiro Toko; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease.
The Journal of biological chemistry 2000;275(45):35291-6.
2000: S Saito; Yukio Hiroi; Yunzeng Zou; Ryuichi Aikawa; Haruhiro Toko; Futoshi Shibasaki; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
beta-Adrenergic pathway induces apoptosis through calcineurin activation in cardiac myocytes.
The Journal of biological chemistry 2000;275(44):34528-33.
2000: Toshimasa Yamauchi; N Yamauchi; Keisuke Ueki; Takashi Sugiyama; Hironori Waki; Hiroshi Miki; Kazuyuki Tobe; S Matsuda; T Tsushima; Tadashi Yamamoto; Tomoyuki Fujita; Y Taketani; Masashi Fukayama; Satoshi Kimura; Yoshio Yazaki; Ryozo Nagai; Takashi Kadowaki
Constitutive tyrosine phosphorylation of ErbB-2 via Jak2 by autocrine secretion of prolactin in human breast cancer.
The Journal of biological chemistry 2000;275(43):33937-44.
2000: Masaki Shimoyama; Doubun Hayashi; Yunzeng Zou; Eiki Takimoto; Miho Mizukami; Koshiro Monzen; Sumiyo Kudoh; Yukio Hiroi; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Calcineurin inhibitor attenuates the development and induces the regression of cardiac hypertrophy in rats with salt-sensitive hypertension.
Circulation 2000;102(16):1996-2004.
2000: Ryuichi Aikawa; Issei Komuro; Ryozo Nagai; Yoshio Yazaki
Rho plays an important role in angiotensin II-induced hypertrophic responses in cardiac myocytes.
Molecular and cellular biochemistry 2000;212(1-2):177-82.
2000: Yukiko Kurihara; Hiroki Kurihara; H Morita; WH Cao; GY Ling; Mamoru Kumada; S Kimura; Ryozo Nagai; Yoshio Yazaki; Tomoyuki Kuwaki
Role of endothelin-1 in stress response in the central nervous system.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(2):R515-21.
2000: Nobukazu Ishizaka; Tadanori Aizawa; Ichiro Mori; Junichi Taguchi; Yoshio Yazaki; Ryozo Nagai; Minoru Ohno
Heme oxygenase-1 is upregulated in the rat heart in response to chronic administration of angiotensin II.
American journal of physiology. Heart and circulatory physiology 2000;279(2):H672-8.
2000: Yasuharu Imai; T Harada; H Yamada; Hiroki Kurihara; Yoshinori Seko; Tadashi Yamazaki; Issei Komuro; K Yamaoki; T Sugiyama; H Ashida; Shinichi Takamoto; Yoshio Yazaki
Left cervical aortic arch with aortic coarctation and saccular aneurysm.
Japanese circulation journal 2000;64(7):544-6.
2000: Hiroyuki Morita; Hiroki Kurihara; Tomoaki Kuwaki; C Hamada; M Kitaoka; S Suzuki; Yoshio Yazaki; Ryozo Nagai
Homocysteine as a risk factor for restenosis after coronary angioplasty.
Thrombosis and haemostasis 2000;84(1):27-31.
2000: Yukio Hiroi; R Chen; H Sawa; Toru Hosoda; Sumiyo Kudoh; Y Kobayashi; Hiroyuki Aburatani; K Nagashima; Ryozo Nagai; Yoshio Yazaki; M Edward Medof; Issei Komuro
Cloning of murine glycosyl phosphatidylinositol anchor attachment protein, GPAA1.
American journal of physiology. Cell physiology 2000;279(1):C205-12.
2000: Ichiro Shiojima; Toru Oka; Yukio Hiroi; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
Transcriptional regulation of human cardiac homeobox gene CSX1.
Biochemical and biophysical research communications 2000;272(3):749-57.
2000: Mineo Kurokawa; Kinuko Mitani; Tetsuya Yamagata; Tokiharu Takahashi; Koji Izutsu; Seishi Ogawa; T Moriguchi; E Nishida; Yoshio Yazaki; Hisamura Hirai
The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death.
The EMBO journal 2000;19(12):2958-68.
2000: Tomoichiro Asano; A Kanda; Hideki Katagiri; Masao Nawano; Toshio Ogihara; Kouichi Inukai; Motonobu Anai; Yasushi Fukushima; Yoshio Yazaki; Masatoshi Kikuchi; R Hooshmand-Rad; C H Heldin; Yoshitaka Oka; Masako Funaki
p110beta is up-regulated during differentiation of 3T3-L1 cells and contributes to the highly insulin-responsive glucose transport activity.
The Journal of biological chemistry 2000;275(23):17671-6.
2000: Weidong Zhu; Yunzeng Zou; Ichiro Shiojima; Sumiyo Kudoh; Ryuichi Aikawa; Doubun Hayashi; Miho Mizukami; Haruhiro Toko; Futoshi Shibasaki; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Ca2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy.
The Journal of biological chemistry 2000;275(20):15239-45.
2000: Takayuki Shindo; Hiroki Kurihara; Koji Maemura; Yukiko Kurihara; Tomoyuki Kuwaki; T Izumida; Naoto Minamino; Kihwan Ju; Hiroyuki Morita; Yoshio Oh-hashi; Mamoru Kumada; Kenji Kangawa; Ryozo Nagai; Yoshio Yazaki
Hypotension and resistance to lipopolysaccharide-induced shock in transgenic mice overexpressing adrenomedullin in their vasculature.
Circulation 2000;101(19):2309-16.
2000: Keisuke Ueki; Toshimasa Yamauchi; H Tamemoto; Kazuyuki Tobe; Ritsuko Yamamoto-Honda; Yasushi Kaburagi; Yasuo Akanuma; Yoshio Yazaki; Shin Aizawa; Ryozo Nagai; Takashi Kadowaki
Restored insulin-sensitivity in IRS-1-deficient mice treated by adenovirus-mediated gene therapy.
The Journal of clinical investigation 2000;105(10):1437-45.
2000: Takayuki Shindo; Hiroki Kurihara; K Kuno; H Yokoyama; T Wada; Yukiko Kurihara; Takasuke Imai; Yuhui Wang; M Ogata; Hiroaki Nishimatsu; Nobuo Moriyama; Yoshio Oh-hashi; Hiroyuki Morita; T Ishikawa; Ryozo Nagai; Yoshio Yazaki; Kouji Matsushima
ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function.
The Journal of clinical investigation 2000;105(10):1345-52.
2000: Eiki Takimoto; T Mizuno; Fumio Terasaki; Masaki Shimoyama; Hiroaki Honda; Ichiro Shiojima; Yukio Hiroi; Toru Oka; Doubun Hayashi; Hisamura Hirai; Sumiyo Kudoh; Haruhiro Toko; K Kawamura; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
Up-regulation of natriuretic peptides in the ventricle of Csx/Nkx2-5 transgenic mice.
Biochemical and biophysical research communications 2000;270(3):1074-9.
2000: T Oka; Ichiro Shiojima; Koshiro Monzen; S Kudoh; Yukio Hiroi; Koichiro Shiokawa; M Asashima; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
Fibroblast growth factor plays a critical role in SM22alpha expression during Xenopus embryogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(4):907-14.
2000: Yasushi Imai; Hiroyuki Morita; Hiroki Kurihara; Takao Sugiyama; N Kato; A Ebihara; C Hamada; Yukiko Kurihara; Takayuki Shindo; Yoshio Oh-hashi; Yoshio Yazaki
Evidence for association between paraoxonase gene polymorphisms and atherosclerotic diseases.
Atherosclerosis 2000;149(2):435-42.
2000: Takahiro Suzuki; K Yamaoki; O Nakajima; Tadashi Yamazaki; Y Yamada; H Akioka; Yoshio Yazaki; Ryozo Nagai
Screening for cardiac dysfunction in asymptomatic patients by measuring B-type natriuretic peptide levels.
Japanese heart journal 2000;41(2):205-14.
2000: Tetsuya Nakamoto; T Yamagata; Ryuichi Sakai; S Ogawa; Hiroaki Honda; H Ueno; Naoto Hirano; Yoshio Yazaki; Hisamura Hirai
CIZ, a zinc finger protein that interacts with p130(cas) and activates the expression of matrix metalloproteinases.
Molecular and cellular biology 2000;20(5):1649-58.
2000: M Miyao; Hiroyuki Morita; Takayuki Hosoi; Hiroki Kurihara; S Inoue; S Hoshino; Masataka Shiraki; Yoshio Yazaki; Y Ouchi
Association of methylenetetrahydrofolate reductase (MTHFR) polymorphism with bone mineral density in postmenopausal Japanese women.
Calcified tissue international 2000;66(3):190-4.
2000: Hiroaki Honda; T Ushijima; K Wakazono; H Oda; Yuji Tanaka; S i Aizawa; T Ishikawa; Yoshio Yazaki; Hisamura Hirai
Acquired loss of p53 induces blastic transformation in p210(bcr/abl)-expressing hematopoietic cells: a transgenic study for blast crisis of human CML.
Blood 2000;95(4):1144-50.
2000: N Morino; Toshihide Mimura; K Hamasaki; Hiroko Kanda; K Kikuchi; K Takehara; Yoshio Yazaki; Yoshihisa Nojima
Impaired collagen gel contraction with cultured skin fibroblasts from patients with systemic sclerosis.
Scandinavian journal of rheumatology 2000;29(2):124-6.
2000: M Horikoshi; Utako Machida; M Itikawa; S Seo; S Masuda; Mineo Kurokawa; Seishi Ogawa; Shinji Sunaga; H Honda; Katsunori Aoki; Shigeru Chiba; Kinuko Mitani; Hisamura Hirai; Yoshio Yazaki
[Essential thrombocythemia in transformation from myelodysplastic syndrome to acute myeloid leukemia with inv(3) after treatment for gastric cancer].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2000;41(1):68-71.
2000: Tokiharu Takahashi; Naoto Hirano; T Takahashi; S Chiba; Yoshio Yazaki; Hisamura Hirai
Immunogene therapy against mouse leukemia using B7 molecules.
Cancer gene therapy 2000;7(1):144-50.
2000: Tadashi Yamazaki; Yoshio Yazaki
Molecular basis of cardiac hypertrophy.
Zeitschrift für Kardiologie 2000;89(1):1-6.
1999: Masaki Shimoyama; Doubun Hayashi; Eiki Takimoto; Yunzeng Zou; Toru Oka; Hiroki Uozumi; Sumiyo Kudoh; Futoshi Shibasaki; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Calcineurin plays a critical role in pressure overload-induced cardiac hypertrophy.
Circulation 1999;100(24):2449-54.
1999: Tomoyuki Kuwaki; GY Ling; M Onodera; Toru Ishii; Akira Nakamura; Kihwan Ju; WH Cao; Mamoru Kumada; Hiroki Kurihara; Yukiko Kurihara; Yoshio Yazaki; Takashi Ohuchi; Masashi Yanagisawa; Yasuichiro Fukuda
Endothelin in the central control of cardiovascular and respiratory functions.
Clinical and experimental pharmacology & physiology 1999;26(12):989-94.
1999: Weidong Zhu; Yunzeng Zou; Ryuichi Aikawa; K Harada; Sumiyo Kudoh; Hiroki Uozumi; Doubun Hayashi; Y Gu; Tadashi Yamazaki; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
MAPK superfamily plays an important role in daunomycin-induced apoptosis of cardiac myocytes.
Circulation 1999;100(20):2100-7.
1999: K Harada; takeshi sugaya; K Murakami; Yoshio Yazaki; Issei Komuro
Angiotensin II type 1A receptor knockout mice display less left ventricular remodeling and improved survival after myocardial infarction.
Circulation 1999;100(20):2093-9.
1999: Kiyoshi Shimizu; Shigeru Chiba; Keiki Kumano; Noriko Hosoya; Tokiharu Takahashi; Yoshinobu Kanda; Yoshio Hamada; Yoshio Yazaki; Hisamura Hirai
Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.
The Journal of biological chemistry 1999;274(46):32961-9.
1999: Ichiro Shiojima; M Aikawa; Jun-Ichi Suzuki; Yoshio Yazaki; Ryozo Nagai
Embryonic smooth muscle myosin heavy chain SMemb is expressed in pressure-overloaded cardiac fibroblasts.
Japanese heart journal 1999;40(6):803-18.
1999: Yasushi Fukushima; Y Ohmachi; Tomoichiro Asano; Masao Nawano; Masako Funaki; Motonobu Anai; Toshio Ogihara; Kouichi Inukai; Yukiko Onishi; Hideyuki Sakoda; Tatsuya Saitoh; Nobuyuki Matsuhashi; Yoshio Yazaki; K Sugano
Localization of the histamine H(2) receptor, a target for antiulcer drugs, in gastric parietal cells.
Digestion 1999;60(6):522-7.
1999: Ryuichi Tozawa; Shun Ishibashi; Jun-ichi Osuga; Hiroaki Yagyu; Toru Oka; Z Chen; Ken Ohashi; S Perrey; Futoshi Shionoiri; Naoya Yahagi; Kenji Harada; Takanari Gotoda; Yoshio Yazaki; Nobuhiro Yamada
Embryonic lethality and defective neural tube closure in mice lacking squalene synthase.
The Journal of biological chemistry 1999;274(43):30843-8.
1999: Masao Nawano; Motonobu Anai; Masako Funaki; H Kobayashi; A Kanda; Yasushi Fukushima; Kouichi Inukai; Toshio Ogihara; Hideyuki Sakoda; Yukiko Onishi; Masatoshi Kikuchi; Yoshio Yazaki; Yoshitaka Oka; Tomoichiro Asano
Imidapril, an angiotensin-converting enzyme inhibitor, improves insulin sensitivity by enhancing signal transduction via insulin receptor substrate proteins and improving vascular resistance in the Zucker fatty rat.
Metabolism: clinical and experimental 1999;48(10):1248-55.
1999: M Takaku; Yoichiro Wada; K Jinnouchi; M Takeya; K Takahashi; Hiroyuki Usuda; Makoto Naito; Hiroki Kurihara; Yoshio Yazaki; Y Kumazawa; Yuri Okimoto; Michihisa Umetani; Noriko Noguchi; Etsuo Niki; Takao Hamakubo; Tsunenori Kodama
An in vitro coculture model of transmigrant monocytes and foam cell formation.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(10):2330-9.
1999: Koshiro Monzen; Ichiro Shiojima; Yukio Hiroi; Sumiyo Kudoh; Toru Oka; Eiki Takimoto; Doubun Hayashi; Toru Hosoda; A Habara-Ohkubo; Takashi Nakaoka; T Fujita; Yoshio Yazaki; Issei Komuro
Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4.
Molecular and cellular biology 1999;19(10):7096-105.
1999: Hiroaki Yagyu; Shun Ishibashi; Z Chen; Jun-ichi Osuga; Mitsuyo Okazaki; S Perrey; Tetsuya Kitamine; M Shimada; Ken Ohashi; Kenji Harada; Futoshi Shionoiri; Naoya Yahagi; Takanari Gotoda; Yoshio Yazaki; Nobuhiro Yamada
Overexpressed lipoprotein lipase protects against atherosclerosis in apolipoprotein E knockout mice.
Journal of lipid research 1999;40(9):1677-85.
1999: Hisamura Hirai; Seishi Ogawa; Mineo Kurokawa; Yoshio Yazaki; Kinuko Mitani
Molecular characterization of the genomic breakpoints in a case of t(3;21)(q26;q22).
Genes, chromosomes & cancer 1999;26(1):92-6.
1999: Hideki Nishimura; Yoshio Yazaki
[Myocardial troponin T].
Nihon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():259-60.
1999: Hideki Nishimura; Yoshio Yazaki
[Myocardial myosin light chain].
Nihon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():256-8.
1999: Yoshinobu Kanda; Shigeru Chiba; Yuji Tanaka; Masahiro Kami; Toshiki Saito; Koji Izutsu; Takashi Asai; Koichiro Yuji; Seishi Ogawa; Hiroaki Honda; Kinuko Mitani; Kensuke Usuki; A Urabe; K Shirakawa; T Yatomi; N Nakamura; Yoshio Yazaki; Hisamura Hirai
Increased serum soluble Fas ligand associated with recurrent B-cell non-Hodgkin's lymphoma after autologous peripheral blood stem cell transplantation.
Leukemia & lymphoma 1999;34(5-6):625-8.
1999: N Morino; Toshio Matsumoto; Keisuke Ueki; Toshihide Mimura; K Hamasaki; Hiroko Kanda; T Naruse; Yoshio Yazaki; Yoshihisa Nojima
Glomerular overexpression and increased tyrosine phosphorylation of focal adhesion kinase p125FAK in lupus-prone MRL/MP-lpr/lpr mice.
Immunology 1999;97(4):634-40.
1999: Yoshinori Seko; N Takahashi; H Oshima; O Shimozato; Hisaya Akiba; Tetsuji Kobata; Hideo Yagita; Ko Okumura; Masahiko Azuma; Yoshio Yazaki
Expression of tumour necrosis factor (TNF) receptor/ligand superfamily co-stimulatory molecules CD40, CD30L, CD27L, and OX40L in murine hearts with chronic ongoing myocarditis caused by coxsackie virus B3.
The Journal of pathology 1999;188(4):423-30.
1999: S Saito; Ryuichi Aikawa; Ichiro Shiojima; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
Endothelin-1 induces expression of fetal genes through the interleukin-6 family of cytokines in cardiac myocytes.
FEBS letters 1999;456(1):103-7.
1999: Masako Funaki; Hideki Katagiri; A Kanda; Motonobu Anai; Masao Nawano; Toshio Ogihara; Kouichi Inukai; Yasushi Fukushima; Hiraku Ono; Yoshio Yazaki; Masatoshi Kikuchi; Yoshitaka Oka; Tomoichiro Asano
p85/p110-type phosphatidylinositol kinase phosphorylates not only the D-3, but also the D-4 position of the inositol ring.
The Journal of biological chemistry 1999;274(31):22019-24.
1999: Ikuo Yokoyama; Shin-ichi Momomura; Tohru Ohtake; Katsunori Yonekura; W Yang; Naoshi Kobayakawa; Teruhiko Aoyagi; Seiryo Sugiura; Nobuhiro Yamada; Kuni Ohtomo; Yasuto Sasaki; Masao Omata; Yoshio Yazaki
Improvement of impaired myocardial vasodilatation due to diffuse coronary atherosclerosis in hypercholesterolemics after lipid-lowering therapy.
Circulation 1999;100(2):117-22.
1999: Yuji Kasaoka; Takeshi Yamashita; Ei-Ichi Fukui; Noriyuki Hayami; Masayasu Inoue; K Sezaki; Yoshio Yazaki; Masao Omata; Yuji Murakawa
A wide "gap" in retrograde conduction through a concealed accessory atrioventricular pathway depending on ventricular pacing sites.
Japanese heart journal 1999;40(4):489-95.
1999: Hiroki Kurihara; Yukiko Kurihara; Ryozo Nagai; Yoshio Yazaki
Endothelin and neural crest development.
Cellular and molecular biology (Noisy-le-Grand, France) 1999;45(5):639-51.
1999: Tadashi Yamazaki; Issei Komuro; Yunzeng Zou; Yoshio Yazaki
Hypertrophic responses of cardiomyocytes induced by endothelin-1 through the protein kinase C-dependent but Src and Ras-independent pathways.
Hypertension research : official journal of the Japanese Society of Hypertension 1999;22(2):113-9.
1999: Hiroaki Honda; K Harada; I Komuro; Fumio Terasaki; Hiroo Ueno; Yuetsu Tanaka; K Kawamura; Yoshio Yazaki; Hisamura Hirai
Heart-specific activation of LTK results in cardiac hypertrophy, cardiomyocyte degeneration and gene reprogramming in transgenic mice.
Oncogene 1999;18(26):3821-30.
1999: Ikuo Yokoyama; Tohru Ohtake; Shin-ichi Momomura; Katsunori Yonekura; Naoshi Kobayakawa; Teruhiko Aoyagi; Seiryo Sugiura; Nobuhiro Yamada; Kuni Ohtomo; Yasuto Sasaki; Masao Omata; Yoshio Yazaki
Insulin action on heart and skeletal muscle FDG uptake in patients with hypertriglyceridemia.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(7):1116-21.
1999: Hideyuki Sakoda; Toshio Ogihara; Motonobu Anai; Masako Funaki; Kouichi Inukai; Hideki Katagiri; Yasushi Fukushima; Yukiko Onishi; Hiraku Ono; Yoshio Yazaki; Masatoshi Kikuchi; Yoshitaka Oka; Tomoichiro Asano
No correlation of plasma cell 1 overexpression with insulin resistance in diabetic rats and 3T3-L1 adipocytes.
Diabetes 1999;48(7):1365-71.
1999: Tadashi Yamazaki; Issei Komuro; I Shiojima; Yoshio Yazaki
The molecular mechanism of cardiac hypertrophy and failure.
Annals of the New York Academy of Sciences 1999;874():38-48.
1999: Tadashi Yamazaki; Issei Komuro; Yoshio Yazaki
Role of the renin-angiotensin system in cardiac hypertrophy.
The American journal of cardiology 1999;83(12A):53H-57H.
1999: N Takahashi; Yoshinori Seko; Eisei Noiri; Kazuyuki Tobe; Takashi Kadowaki; H Sabe; Yoshio Yazaki
Vascular endothelial growth factor induces activation and subcellular translocation of focal adhesion kinase (p125FAK) in cultured rat cardiac myocytes.
Circulation research 1999;84(10):1194-202.
1999: Shuichi Otabe; Kazuki Yasuda; Yasumichi Mori; K Shimokawa; Hiroko Kadowaki; A Jimi; K Nonaka; Yasuo Akanuma; Yoshio Yazaki; Takashi Kadowaki
Molecular and histological evaluation of pancreata from patients with a mitochondrial gene mutation associated with impaired insulin secretion.
Biochemical and biophysical research communications 1999;259(1):149-56.
1999: Yoshinori Seko; N Takahashi; Kazuyuki Tobe; Takashi Kadowaki; Yoshio Yazaki
Pulsatile stretch activates mitogen-activated protein kinase (MAPK) family members and focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes.
Biochemical and biophysical research communications 1999;259(1):8-14.
1999: Kazuhiro Maki; Kinuko Mitani; Tetsuya Yamagata; Mineo Kurokawa; Yoshinobu Kanda; Yoshio Yazaki; Hisamura Hirai
Transcriptional inhibition of p53 by the MLL/MEN chimeric protein found in myeloid leukemia.
Blood 1999;93(10):3216-24.
1999: Toru Hosoda; Issei Komuro; Ichiro Shiojima; Yukio Hiroi; M Harada; Yuji Murakawa; Yasunobu Hirata; Yoshio Yazaki
Familial atrial septal defect and atrioventricular conduction disturbance associated with a point mutation in the cardiac homeobox gene CSX/NKX2-5 in a Japanese patient.
Japanese circulation journal 1999;63(5):425-6.
1999: Hiroko Kanda; Toshihide Mimura; K Hamasaki; K Yamamoto; Yoshio Yazaki; H Hirai; Yoshihisa Nojima
Fyn and Lck tyrosine kinases regulate tyrosine phosphorylation of p105CasL, a member of the p130Cas docking protein family, in T-cell receptor-mediated signalling.
Immunology 1999;97(1):56-61.
1999: Yoshinori Seko; N Takahashi; Hideo Yagita; Ko Okumura; Masahiko Azuma; Yoshio Yazaki
Effects of in vivo administration of anti-B7-1/B7-2 monoclonal antibodies on the survival of mice with chronic ongoing myocarditis caused by Coxsackievirus B3.
The Journal of pathology 1999;188(1):107-12.
1999: Hiroaki Honda; T Inaba; Takahiro Suzuki; H Oda; Yasuhiro Ebihara; K Tsuiji; Tatsutoshi Nakahata; T Ishikawa; Yoshio Yazaki; Hisamura Hirai
Expression of E2A-HLF chimeric protein induced T-cell apoptosis, B-cell maturation arrest, and development of acute lymphoblastic leukemia.
Blood 1999;93(9):2780-90.
1999: Yasumichi Mori; H Kim-Motoyama; Yoshiaki Ito; T Katakura; Kazuki Yasuda; S Ishiyama-Shigemoto; K Yamada; Yasuo Akanuma; Y Ohashi; Satoshi Kimura; Yoshio Yazaki; Takashi Kadowaki
The Gln27Glu beta2-adrenergic receptor variant is associated with obesity due to subcutaneous fat accumulation in Japanese men.
Biochemical and biophysical research communications 1999;258(1):138-40.
1999: Yoshinobu Kanda; Yuji Tanaka; Masahiro Kami; Toshiki Saito; Takashi Asai; Koji Izutsu; Koichiro Yuji; Seishi Ogawa; Hiroaki Honda; Kinuko Mitani; Shigeru Chiba; Yoshio Yazaki; Hisamura Hirai
TT virus in bone marrow transplant recipients.
Blood 1999;93(8):2485-90.
1999: Yunzeng Zou; Issei Komuro; Tadashi Yamazaki; Sumiyo Kudoh; Hiroki Uozumi; Takashi Kadowaki; Yoshio Yazaki
Both Gs and Gi proteins are critically involved in isoproterenol-induced cardiomyocyte hypertrophy.
The Journal of biological chemistry 1999;274(14):9760-70.
1999: Yoshinobu Kanda; Shigeru Chiba; Yuji Tanaka; A Miwa; A Togawa; Takashi Kato; H Miyazaki; R Nishino; Yoshio Yazaki; Hisamura Hirai
Serial serum thrombopoietin levels in a pregnant woman with essential thrombocythaemia.
British journal of haematology 1999;105(1):271-3.
1999: Ichiro Shiojima; Issei Komuro; Toru Oka; Yukio Hiroi; T Mizuno; Eiki Takimoto; Koshiro Monzen; Ryuichi Aikawa; Hiroshi Akazawa; Tadashi Yamazaki; Sumiyo Kudoh; Yoshio Yazaki
Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx-2.5 and GATA-4.
The Journal of biological chemistry 1999;274(12):8231-9.
1999: Ryuichi Aikawa; Issei Komuro; Tadashi Yamazaki; Yunzeng Zou; Sumiyo Kudoh; W Zhu; Takashi Kadowaki; Yoshio Yazaki
Rho family small G proteins play critical roles in mechanical stress-induced hypertrophic responses in cardiac myocytes.
Circulation research 1999;84(4):458-66.
1999: Yasushi Kaburagi; Toshimasa Yamauchi; Ritsuko Yamamoto-Honda; Keisuke Ueki; Kazuyuki Tobe; Yasuo Akanuma; Yoshio Yazaki; Takashi Kadowaki
The mechanism of insulin-induced signal transduction mediated by the insulin receptor substrate family.
Endocrine journal 1999;46 Suppl():S25-34.
1999: Yoshikazu Shibasaki; H Ishihara; Yoshitaka Oka; Yoshio Yazaki
[Phosphatidylinositol 5-kinases].
Seikagaku. The Journal of Japanese Biochemical Society 1999;71(3):193-7.
1999: Hiroyuki Morita; Hiroki Kurihara; Yukiko Kurihara; Tomoyuki Kuwaki; Takayuki Shindo; Yoshio Oh-hashi; Mamoru Kumada; Yoshio Yazaki
Responses of blood pressure and catecholamine metabolism to high salt loading in endothelin-1 knockout mice.
Hypertension research : official journal of the Japanese Society of Hypertension 1999;22(1):11-6.
1999: M Itoh; Takao Aoyama; Yoshikazu Yamamura; Katsuyoshi Nakajima; K Nakamura; H Kotaki; T Matsuyama; T Saitoh; M Kami; Shigeru Chiba; Hisamura Hirai; Yoshio Yazaki; Tatsuji Iga
[Effects of the rational use of corticosteroids eye drops for the prevention of ocular toxicity in high-dose cytosine arabinoside therapy].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1999;119(3):229-35.
1999: Yoshinobu Kanda; Shigeru Chiba; Hiroaki Honda; Hisamura Hirai; Yoshio Yazaki
Long-term third chronic phase of chronic myelogenous leukemia maintained by interferon-alpha and methotrexate.
Leukemia & lymphoma 1999;33(1-2):193-7.
1999: Kenji Harada; Issei Komuro; Takeshi Sugaya; Koji Murakami; Yoshio Yazaki
Vascular injury causes neointimal formation in angiotensin II type 1a receptor knockout mice.
Circulation research 1999;84(2):179-85.
1999: Hiroyuki Morita; Hiroki Kurihara; Takao Sugiyama; K Kitamura; Shin Suzuki; Tetsuya Sumiyoshi; Yoshio Yazaki
[Genetic polymorphisms of methylenetetrahydrofolate reductase and methionine synthase: association with homocysteine metabolism and late-onset vascular diseases in the Japanese population].
Journal of cardiology 1999;33(2):106-7.
1999: Hiroyuki Morita; Hiroki Kurihara; Takao Sugiyama; C Hamada; Yukiko Kurihara; Takayuki Shindo; Yoshio Oh-hashi; Yoshio Yazaki
Polymorphism of the methionine synthase gene : association with homocysteine metabolism and late-onset vascular diseases in the Japanese population.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(2):298-302.
1999: Yoshinori Seko; Y Seko; N Takahashi; Masabumi Shibuya; Yoshio Yazaki
Pulsatile stretch stimulates vascular endothelial growth factor (VEGF) secretion by cultured rat cardiac myocytes.
Biochemical and biophysical research communications 1999;254(2):462-5.
1999: N Takahashi; T Kadowaki; Yoshio Yazaki; Graham C R Ellis-Davies; Yasushi Miyashita; Haruo Kasai
Post-priming actions of ATP on Ca2+-dependent exocytosis in pancreatic beta cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(2):760-5.
1999: H Ishihara; Teiji Wada; N Kizuki; Tomoichiro Asano; Yoshio Yazaki; Masatoshi Kikuchi; Yoshitaka Oka
Enhanced phosphoinositide hydrolysis via overexpression of phospholipase C beta1 or delta1 inhibits stimulus-induced insulin release in insulinoma MIN6 cells.
Biochemical and biophysical research communications 1999;254(1):77-82.
1999: Yoshinobu Kanda; Shigeru Chiba; Yuji Tanaka; Masahiro Kami; Toshiki Saito; Takashi Asai; Koji Izutsu; Koichiro Yuji; Seishi Ogawa; Hiroaki Honda; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
TT virus in frequently transfused patients.
The American journal of medicine 1999;106(1):116-7.
1999: N Takahashi; Yoshinori Seko; Masahiko Azuma; Hideo Yagita; Ko Okumura; Yoshio Yazaki
Evidence of cell-mediated cardiac myocyte injury involved in the heart failure of a patient with progressive systemic sclerosis.
Japanese circulation journal 1999;63(1):68-72.
1999: Yoshio Yazaki; T Matsushima; Kiyoshi Aoki
Testosterone modulates stimulation-induced calling behavior in Japanese quails.
Journal of comparative physiology. A, Sensory, neural, and behavioral physiology 1999;184(1):13-9.
1999: Tadashi Yamazaki; Yoshio Yazaki
Role of tissue angiotensin II in myocardial remodelling induced by mechanical stress.
Journal of human hypertension 1999;13 Suppl 1():S43-7; discussion S49-50.
1999: Motonobu Anai; Masako Funaki; Toshio Ogihara; A Kanda; Yukiko Onishi; Hideyuki Sakoda; Kouichi Inukai; Masao Nawano; Yasushi Fukushima; Yoshio Yazaki; Masatoshi Kikuchi; Yoshitaka Oka; Tomoichiro Asano
Enhanced insulin-stimulated activation of phosphatidylinositol 3-kinase in the liver of high-fat-fed rats.
Diabetes 1999;48(1):158-69.
1999: Y Takahashi; Yasuo Akanuma; Yoshio Yazaki; Takashi Kadowaki
Formation of distinct signalling complexes involving phosphatidylinositol 3-kinase activity with stimulation of epidermal growth factor or insulin-like growth factor-I in human skin fibroblasts.
Journal of cellular physiology 1999;178(1):69-75.
1998: Haruko Yokoyama; Takao Aoyama; T Matsuyama; Yoshikazu Yamamura; Katsuyoshi Nakajima; K Nakamura; Hajime Sato; H Kotaki; Shigeru Chiba; Hisamura Hirai; Yoshio Yazaki; Tatsuji Iga
[The cause of polyurethane catheter cracking during constant infusion of etoposide (VP-16) injection].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1998;118(12):581-8.
1998: Koji Murakami; Kazuyuki Tobe; Tomohiro Ide; T Mochizuki; M Ohashi; Yasuo Akanuma; Yoshio Yazaki; Takashi Kadowaki
A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats.
Diabetes 1998;47(12):1841-7.
1998: Mineo Kurokawa; Kinuko Mitani; Yoichi Imai; Seishi Ogawa; Yoshio Yazaki; Hisamura Hirai
The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-beta-mediated growth inhibition of myeloid cells.
Blood 1998;92(11):4003-12.
1998: Yukio Hiroi; Issei Komuro; Ikumi Matsushita; Hiroyuki Aburatani; Toru Hosoda; Yutaka Nakahori; M Edward Medof; Yoshio Yazaki
Assignment of the human GPAA1 gene, which encodes a product required for the attachment of glycosylphosphatidylinositols to proteins, at 8q24.
Genomics 1998;54(2):354-5.
1998: Yoichi Imai; Mineo Kurokawa; Keiichi Tanaka; Alan D Friedman; Seishi Ogawa; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
TLE, the human homolog of groucho, interacts with AML1 and acts as a repressor of AML1-induced transactivation.
Biochemical and biophysical research communications 1998;252(3):582-9.
1998: Seishi Ogawa; Akira Oku; Asako Sawano; Sachiko Yamaguchi; Yoshio Yazaki; Masabumi Shibuya
A novel type of vascular endothelial growth factor, VEGF-E (NZ-7 VEGF), preferentially utilizes KDR/Flk-1 receptor and carries a potent mitotic activity without heparin-binding domain.
The Journal of biological chemistry 1998;273(47):31273-82.
1998: Motonobu Anai; Hiraku Ono; Masako Funaki; Yasushi Fukushima; Kouichi Inukai; Toshio Ogihara; Hideyuki Sakoda; Yukiko Onishi; Yoshio Yazaki; Masatoshi Kikuchi; Yoshitaka Oka; Tomoichiro Asano
Different subcellular distribution and regulation of expression of insulin receptor substrate (IRS)-3 from those of IRS-1 and IRS-2.
The Journal of biological chemistry 1998;273(45):29686-92.
1998: GY Ling; WH Cao; M Onodera; Kihwan Ju; Hiroki Kurihara; Yukiko Kurihara; Yoshio Yazaki; Mamoru Kumada; Yasuichiro Fukuda; Tomoyuki Kuwaki
Renal sympathetic nerve activity in mice: comparison between mice and rats and between normal and endothelin-1 deficient mice.
Brain research 1998;808(2):238-49.
1998: Yasumichi Mori; H Kim-Motoyama; T Katakura; Kazuki Yasuda; Hiroko Kadowaki; Brock A Beamer; Alan R Shuldiner; Yasuo Akanuma; Yoshio Yazaki; Takashi Kadowaki
Effect of the Pro12Ala variant of the human peroxisome proliferator-activated receptor gamma 2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men.
Biochemical and biophysical research communications 1998;251(1):195-8.
1998: Yoshinobu Kanda; Yuji Tanaka; K Shirakawa; T Yatomi; N Nakamura; Masahiro Kami; Toshiki Saito; Koji Izutsu; Takashi Asai; Koichiro Yuji; Seishi Ogawa; Hiroaki Honda; Kinuko Mitani; Shigeru Chiba; Yoshio Yazaki; Hisamura Hirai
Increased soluble Fas-ligand in sera of bone marrow transplant recipients with acute graft-versus-host disease.
Bone marrow transplantation 1998;22(8):751-4.
1998: Ryuichi Aikawa; Yoshio Yazaki
[Biochemical markers for acute coronary syndromes].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(10):2569-75.
1998: Sumiyo Kudoh; Issei Komuro; Yukio Hiroi; Yunzeng Zou; Kenji Harada; Takeshi Sugaya; N Takekoshi; Koji Murakami; Takashi Kadowaki; Yoshio Yazaki
Mechanical stretch induces hypertrophic responses in cardiac myocytes of angiotensin II type 1a receptor knockout mice.
The Journal of biological chemistry 1998;273(37):24037-43.
1998: T Itoh; Toshihiro Tanaka; Ryozo Nagai; K Kikuchi; Seishi Ogawa; S Okada; S Yamagata; K Yano; Yoshio Yazaki; Yusuke Nakamura
Genomic organization and mutational analysis of KVLQT1, a gene responsible for familial long QT syndrome.
Human genetics 1998;103(3):290-4.
1998: Hiroyuki Morita; Hiroki Kurihara; S Tsubaki; Takao Sugiyama; C Hamada; Yukiko Kurihara; Takayuki Shindo; Yoshio Oh-hashi; K Kitamura; Yoshio Yazaki
Methylenetetrahydrofolate reductase gene polymorphism and ischemic stroke in Japanese.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(9):1465-9.
1998: Yoshinori Seko; N Takahashi; Masahiko Azuma; Hideo Yagita; Ko Okumura; Yoshio Yazaki
Expression of costimulatory molecule CD40 in murine heart with acute myocarditis and reduction of inflammation by treatment with anti-CD40L/B7-1 monoclonal antibodies.
Circulation research 1998;83(4):463-9.
1998: T Hayakawa; Mitsuhiko Noda; Kazuki Yasuda; H Yorifuji; Shun'ichiro Taniguchi; Ichitomo Miwa; H Sakura; Yasuo Terauchi; J Hayashi; Geoffrey W G Sharp; Y Kanazawa; Yasuo Akanuma; Yoshio Yazaki; Takashi Kadowaki
Ethidium bromide-induced inhibition of mitochondrial gene transcription suppresses glucose-stimulated insulin release in the mouse pancreatic beta-cell line betaHC9.
The Journal of biological chemistry 1998;273(32):20300-7.
1998: Ken Ohashi; Shun Ishibashi; Masayuki Yamamoto; Jun-ichi Osuga; Yoshio Yazaki; S Yukawa; Nobuhiro Yamada
A truncated species of apolipoprotein B (B-38.7) in a patient with homozygous hypobetalipoproteinemia associated with diabetes mellitus.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(8):1330-4.
1998: Takahiro Suzuki; D Hayashi; Tadashi Yamazaki; T Mizuno; Y Kanda; Issei Komuro; Masahiko Kurabayashi; K Yamaoki; K Mitani; H Hirai; Ryozo Nagai; Yoshio Yazaki
Elevated B-type natriuretic peptide levels after anthracycline administration.
American heart journal 1998;136(2):362-3.
1998: Hiroaki Honda; Hiromi Oda; Tetsuya Nakamoto; Zen-ichiro Honda; Ryuichi Sakai; Takahiro Suzuki; T Saito; Kozo Nakamura; K Nakao; T Ishikawa; M Katsuki; Yoshio Yazaki; Hisamura Hirai
Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas.
Nature genetics 1998;19(4):361-5.
1998: Jun-ichi Osuga; M Yonemoto; Nobuhiro Yamada; Hitoshi Shimano; Hiroaki Yagyu; Ken Ohashi; Kenji Harada; T Kamei; Yoshio Yazaki; Shun Ishibashi
Cholesterol lowering in low density lipoprotein receptor knockout mice overexpressing apolipoprotein E.
The Journal of clinical investigation 1998;102(2):386-94.
1998: Mineo Kurokawa; Kinuko Mitani; K Irie; T Matsuyama; Tokiharu Takahashi; Shigeru Chiba; Yoshio Yazaki; Kunio Matsumoto; Hisamura Hirai
The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3.
Nature 1998;394(6688):92-6.
1998: Takahiro Suzuki; Ryozo Nagai; Yoshio Yazaki
Mechanisms of transcriptional regulation of gene expression in smooth muscle cells.
Circulation research 1998;82(12):1238-42.
1998: Toshimasa Yamauchi; Yasushi Kaburagi; Keisuke Ueki; Y Tsuji; G R Stark; I M Kerr; T Tsushima; Yasuo Akanuma; Issei Komuro; Kazuyuki Tobe; Yoshio Yazaki; Takashi Kadowaki
Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase.
The Journal of biological chemistry 1998;273(25):15719-26.
1998: Tokiharu Takahashi; K Yamada; Toshihiro Tanaka; Keiki Kumano; Mineo Kurokawa; Naoto Hirano; Hiroaki Honda; Shigeru Chiba; Kunikazu Tsuji; Yoshio Yazaki; Tatsutoshi Nakahata; Hisamura Hirai
A potential molecular approach to ex vivo hematopoietic expansion with recombinant epidermal growth factor receptor-expressing adenovirus vector.
Blood 1998;91(12):4509-15.
1998: L Sun; Shun Ishibashi; Jun-ichi Osuga; Kenji Harada; Ken Ohashi; Takanari Gotoda; Y Fukuo; Yoshio Yazaki; Nobuhiro Yamada
Clinical features associated with the homozygous Trp64Arg mutation of the beta3-adrenergic receptor: no evidence for its association with obesity in Japanese.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(6):941-6.
1998: Yoshinori Seko; N Takahashi; Kazuyuki Tobe; K Ueki; Takashi Kadowaki; Yoshio Yazaki
Vascular endothelial growth factor (VEGF) activates Raf-1, mitogen-activated protein (MAP) kinases, and S6 kinase (p90rsk) in cultured rat cardiac myocytes.
Journal of cellular physiology 1998;175(3):239-46.
1998: K Harada; Issei Komuro; Ichiro Shiojima; Doubun Hayashi; Sumiyo Kudoh; T Mizuno; K Kijima; H Matsubara; takeshi sugaya; K Murakami; Yoshio Yazaki
Pressure overload induces cardiac hypertrophy in angiotensin II type 1A receptor knockout mice.
Circulation 1998;97(19):1952-9.
1998: Kenji Harada; Issei Komuro; Yunzeng Zou; Sumiyo Kudoh; K Kijima; H Matsubara; Takeshi Sugaya; Koji Murakami; Yoshio Yazaki
Acute pressure overload could induce hypertrophic responses in the heart of angiotensin II type 1a knockout mice.
Circulation research 1998;82(7):779-85.
1998: H Abe; Nobuhiro Yamada; K Kamata; T Kuwaki; M Shimada; Jun-ichi Osuga; Futoshi Shionoiri; Naoya Yahagi; Takashi Kadowaki; H Tamemoto; Shun Ishibashi; Yoshio Yazaki; M Makuuchi
Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1.
The Journal of clinical investigation 1998;101(8):1784-8.
1998: H Ishihara; Yoshikazu Shibasaki; N Kizuki; Teiji Wada; Yoshio Yazaki; Tomoichiro Asano; Yoshitaka Oka
Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family.
The Journal of biological chemistry 1998;273(15):8741-8.
1998: Takayuki Shindo; Hiroki Kurihara; N Ohishi; Hiroyuki Morita; K Maemua; Yukiko Kurihara; H Tsuneyoshi; H Chi; K Yamaoki; Yoshio Yazaki
Images in cardiovascular medicine. Cardiac sarcoidosis.
Circulation 1998;97(13):1306-7.
1998: Toshimasa Yamauchi; Keisuke Ueki; Kazuyuki Tobe; H Tamemoto; Nobuo Sekine; M Wada; M Honjo; Michio Takahashi; Tokiharu Takahashi; Hisamura Hirai; T Tsushima; Yasuo Akanuma; Tomoyuki Fujita; Issei Komuro; Yoshio Yazaki; Takashi Kadowaki
Growth hormone-induced tyrosine phosphorylation of EGF receptor as an essential element leading to MAP kinase activation and gene expression.
Endocrine journal 1998;45 Suppl():S27-31.
1998: T Itoh; Toshihiro Tanaka; Ryozo Nagai; T Kamiya; T Sawayama; T Nakayama; Hitonobu Tomoike; Harumizu Sakurada; Yoshio Yazaki; Yusuke Nakamura
Genomic organization and mutational analysis of HERG, a gene responsible for familial long QT syndrome.
Human genetics 1998;102(4):435-9.
1998: Masahiro Kami; Yoshinobu Kanda; M Sasaki; N Takeda; Yuji Tanaka; Toshiki Saito; Seishi Ogawa; Hiroaki Honda; Shigeru Chiba; Kinuko Mitani; Hisamura Hirai; Yoshio Yazaki
Phimosis as a manifestation of chronic graft-versus-host disease after allogeneic bone marrow transplantation.
Bone marrow transplantation 1998;21(7):721-3.
1998: J Terasaki; Motonobu Anai; Masako Funaki; T Shibata; Kouichi Inukai; Toshio Ogihara; H Ishihara; Hideki Katagiri; Yukiko Onishi; Hideyuki Sakoda; Yasushi Fukushima; Yoshio Yazaki; Masatoshi Kikuchi; Yoshitaka Oka; Tomoichiro Asano
Role of JTT-501, a new insulin sensitiser, in restoring impaired GLUT4 translocation in adipocytes of rats fed a high fat diet.
Diabetologia 1998;41(4):400-9.
1998: Yoshinori Seko; N Takahashi; Masahiko Azuma; Hideo Yagita; Ko Okumura; Yoshio Yazaki
Effects of in vivo administration of anti-B7-1/B7-2 monoclonal antibodies on murine acute myocarditis caused by coxsackievirus B3.
Circulation research 1998;82(5):613-8.
1998: Akira Okuno; H Tamemoto; Kazuyuki Tobe; Keisuke Ueki; Y Mori; K Iwamoto; K Umesono; Yasuo Akanuma; Toshihiko Fujiwara; H Horikoshi; Yoshio Yazaki; Takashi Kadowaki
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats.
The Journal of clinical investigation 1998;101(6):1354-61.
1998: Hiroaki Honda; H Oda; Takahiro Suzuki; Tokiharu Takahashi; Owen N Witte; Keiya Ozawa; T Ishikawa; Yoshio Yazaki; Hisamura Hirai
Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: a novel transgenic model for human Ph1-positive leukemias.
Blood 1998;91(6):2067-75.
1998: Tadashi Yamazaki; Issei Komuro; Sumiyo Kudoh; Yunzeng Zou; Ryozo Nagai; Ryuichi Aikawa; Hiroki Uozumi; Yoshio Yazaki
Role of ion channels and exchangers in mechanical stretch-induced cardiomyocyte hypertrophy.
Circulation research 1998;82(4):430-7.
1998: Y Kanda; M Kami; T Matsuyama; K Mitani; S Chiba; Yoshio Yazaki; H Hirai
Plasma concentration of itraconazole in patients receiving chemotherapy for hematological malignancies: the effect of famotidine on the absorption of itraconazole.
Hematological oncology 1998;16(1):33-7.
1998: Tokiharu Takahashi; Yoshinobu Kanda; M Mori; Toshiki Saito; Shigeru Chiba; Kinuko Mitani; Hisamura Hirai; Yoshio Yazaki
B cell lymphoma-associated hemophagocytic syndrome after PBSCT.
Bone marrow transplantation 1998;21(6):623-5.
1998: Hiroaki Honda; S Ohno; Tokiharu Takahashi; M Takatoku; Yoshio Yazaki; Hisamura Hirai
Establishment, characterization, and chromosomal analysis of new leukemic cell lines derived from MT/p210bcr/abl transgenic mice.
Experimental hematology 1998;26(3):188-97.
1998: Hiroyuki Takano; Issei Komuro; Toru Oka; Ichiro Shiojima; Yukio Hiroi; T Mizuno; Yoshio Yazaki
The Rho family G proteins play a critical role in muscle differentiation.
Molecular and cellular biology 1998;18(3):1580-9.
1998: Keiichi Tanaka; Toshihiro Tanaka; Mineo Kurokawa; Yoichi Imai; Seishi Ogawa; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
The AML1/ETO(MTG8) and AML1/Evi-1 leukemia-associated chimeric oncoproteins accumulate PEBP2beta(CBFbeta) in the nucleus more efficiently than wild-type AML1.
Blood 1998;91(5):1688-99.
1998: Keisuke Ueki; Ritsuko Yamamoto-Honda; Yasushi Kaburagi; Toshimasa Yamauchi; Kazuyuki Tobe; Boudewijn M T Burgering; Paul J Coffer; Issei Komuro; Yasuo Akanuma; Yoshio Yazaki; Takashi Kadowaki
Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis.
The Journal of biological chemistry 1998;273(9):5315-22.
1998: Yoshinobu Kanda; Kinuko Mitani; Mineo Kurokawa; Tetsuya Yamagata; Yoshio Yazaki; Hisamura Hirai
Overexpression of the MEN/ELL protein, an RNA polymerase II elongation factor, results in transformation of Rat1 cells with dependence on the lysine-rich region.
The Journal of biological chemistry 1998;273(9):5248-52.
1998: Yoshinori Seko; N Takahashi; Shigeru Ishiyama; Toshiro Nishikawa; Takeshi Kasajima; Michiaki Hiroe; Shin Suzuki; Sugao Ishiwata; S Kawai; Masahiko Azuma; Hideo Yagita; Ko Okumura; Yoshio Yazaki
Expression of costimulatory molecules B7-1, B7-2, and CD40 in the heart of patients with acute myocarditis and dilated cardiomyopathy.
Circulation 1998;97(7):637-9.
1998: Yunzeng Zou; Issei Komuro; Tadashi Yamazaki; Sumiyo Kudoh; Ryuichi Aikawa; W Zhu; Ichiro Shiojima; Yukio Hiroi; Kazuyuki Tobe; Takashi Kadowaki; Yoshio Yazaki
Cell type-specific angiotensin II-evoked signal transduction pathways: critical roles of Gbetagamma subunit, Src family, and Ras in cardiac fibroblasts.
Circulation research 1998;82(3):337-45.
1998: K Harada; Issei Komuro; Doubun Hayashi; takeshi sugaya; K Murakami; Yoshio Yazaki
Angiotensin II type 1a receptor is involved in the occurrence of reperfusion arrhythmias.
Circulation 1998;97(4):315-7.
1998: Y Kitano; Hiroki Kurihara; Yukiko Kurihara; K Maemura; Y Ryo; Yoshio Yazaki; Kiyonori Harii
Gene expression of bone matrix proteins and endothelin receptors in endothelin-1-deficient mice revealed by in situ hybridization.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(2):237-44.
1998: Yasuhiro Takahashi; Hiroko Kadowaki; A Ando; J D Quin; A C MacCuish; Yoshio Yazaki; Yasuo Akanuma; Takashi Kadowaki
Two aberrant splicings caused by mutations in the insulin receptor gene in cultured lymphocytes from a patient with Rabson-Mendenhall's syndrome.
The Journal of clinical investigation 1998;101(3):588-94.
1998: Yukio Hiroi; Issei Komuro; R Chen; Toru Hosoda; T Mizuno; Sumiyo Kudoh; S P Georgescu; M Edward Medof; Yoshio Yazaki
Molecular cloning of human homolog of yeast GAA1 which is required for attachment of glycosylphosphatidylinositols to proteins.
FEBS letters 1998;421(3):252-8.
1998: Hiroyuki Morita; Hiroki Kurihara; Yukiko Kurihara; Takayuki Shindo; Tomoyuki Kuwaki; Mamoru Kumada; Yoshio Yazaki
Systemic and renal response to salt loading in endothelin-1 knockout mice.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S557-60.
1998: Takayuki Shindo; Hiroki Kurihara; Yukiko Kurihara; Hiroyuki Morita; Yoshio Yazaki
Upregulation of endothelin-1 and adrenomedullin gene expression in the mouse endotoxin shock model.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S541-4.
1998: Yoshinobu Kanda; Shigeru Chiba; T Suzuki; Masahiro Kami; Yoshio Yazaki; Hisamura Hirai
Time course analysis of semi-quantitative PCR and antigenaemia assay for prevention of cytomegalovirus disease after bone marrow transplantation.
British journal of haematology 1998;100(1):222-5.
1998: T Yamazaki; Issei Komuro; Yunzeng Zou; Sumiyo Kudoh; Ichiro Shiojima; T Mizuno; Yukio Hiroi; Ryozo Nagai; Yoshio Yazaki
Efficient inhibition of the development of cardiac remodeling by a long-acting calcium antagonist amlodipine.
Hypertension 1998;31(1):32-8.
1998: Motonobu Anai; Masako Funaki; Toshio Ogihara; J Terasaki; Kouichi Inukai; Hideki Katagiri; Yasushi Fukushima; Yoshio Yazaki; Masatoshi Kikuchi; Yoshitaka Oka; Tomoichiro Asano
Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats.
Diabetes 1998;47(1):13-23.
1998: Hiroo Ueno; Kazuki Sasaki; Hiroaki Honda; Tetsuya Nakamoto; Tetsuya Yamagata; Kiyoshi Miyagawa; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
c-Cbl is tyrosine-phosphorylated by interleukin-4 and enhances mitogenic and survival signals of interleukin-4 receptor by linking with the phosphatidylinositol 3'-kinase pathway.
Blood 1998;91(1):46-53.
1997: Kenji Harada; Z Chen; Shun Ishibashi; Jun-ichi Osuga; Hiroaki Yagyu; Ken Ohashi; Naoya Yahagi; Futoshi Shionoiri; L Sun; Yoshio Yazaki; Nobuhiro Yamada
Apoptotic cell death in atherosclerotic plaques of hyperlipidemic knockout mice.
Atherosclerosis 1997;135(2):235-9.
1997: Yoshinori Seko; Osamu Sato; A Takagi; Yusuke Tada; H Matsuo; Hideo Yagita; Ko Okumura; Yoshio Yazaki
Perforin-secreting killer cell infiltration in the aortic tissue of patients with atherosclerotic aortic aneurysm.
Japanese circulation journal 1997;61(12):965-70.
1997: Toshimasa Yamauchi; Keisuke Ueki; Kazuyuki Tobe; H Tamemoto; Nobuo Sekine; M Wada; M Honjo; Michio Takahashi; Tokiharu Takahashi; Hisamura Hirai; T Tushima; Yasuo Akanuma; Tomoyuki Fujita; Issei Komuro; Yoshio Yazaki; Takashi Kadowaki
Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone.
Nature 1997;390(6655):91-6.
1997: H Miura; T Miyazaki; M Kuroda; T Oka; Rikuo Machinami; Tsunenori Kodama; Masabumi Shibuya; Makuuchi Masatoshi; Yoshio Yazaki; S Ohnishi
Increased expression of vascular endothelial growth factor in human hepatocellular carcinoma.
Journal of hepatology 1997;27(5):854-61.
1997: Yoshinori Seko; N Takahashi; Kazuyuki Tobe; Takashi Kadowaki; Yoshio Yazaki
Hypoxia and hypoxia/reoxygenation activate p65PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes.
Biochemical and biophysical research communications 1997;239(3):840-4.
1997: Ichiro Manabe; Masahiko Kurabayashi; Yoshiharu Shimomura; Makoto Kuro-o; Nobukazu Watanabe; Masahiko Watanabe; M Aikawa; Takahiro Suzuki; Yoshio Yazaki; Ryozo Nagai
Isolation of the embryonic form of smooth muscle myosin heavy chain (SMemb/NMHC-B) gene and characterization of its 5'-flanking region.
Biochemical and biophysical research communications 1997;239(2):598-605.
1997: Yasushi Kaburagi; Shinobu Satoh; H Tamemoto; Ritsuko Yamamoto-Honda; Kazuyuki Tobe; K Veki; Toshimasa Yamauchi; E Kono-Sugita; Hisahiko Sekihara; Shin Aizawa; S W Cushman; Yasuo Akanuma; Yoshio Yazaki; Takashi Kadowaki
Role of insulin receptor substrate-1 and pp60 in the regulation of insulin-induced glucose transport and GLUT4 translocation in primary adipocytes.
The Journal of biological chemistry 1997;272(41):25839-44.
1997: H Kim-Motoyama; Tokio Yamaguchi; T Katakura; Masayuki Miura; Y Ohashi; Yoshio Yazaki; T Kadawaki
Serum leptin levels are associated with hyperinsulinemia independent of body mass index but not with visceral obesity.
Biochemical and biophysical research communications 1997;239(1):340-4.
1997: Toshio Ogihara; Toshiaki Isobe; Tohru Ichimura; Masato Taoka; Masako Funaki; Hideyuki Sakoda; Yukiko Onishi; Kouichi Inukai; Motonobu Anai; Yasushi Fukushima; Masatoshi Kikuchi; Yoshio Yazaki; Yoshitaka Oka; Tomoichiro Asano
14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain.
The Journal of biological chemistry 1997;272(40):25267-74.
1997: Yoshinobu Kanda; Shigeru Chiba; Naoto Hirano; Hisamura Hirai; Yoshio Yazaki
Rapid progression of chronic myelomonocytic leukemia following diaminodiphenyl sulphone treatment for dermatitis herpetiformis.
International journal of hematology 1997;66(3):383-5.
1997: Ryuichi Aikawa; Issei Komuro; T Yamazaki; Y Zou; S Kudoh; M Tanaka; Ichiro Shiojima; Yukio Hiroi; Yoshio Yazaki
Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats.
The Journal of clinical investigation 1997;100(7):1813-21.
1997: Yoshinori Seko; N Takahashi; Hideo Yagita; Ko Okumura; Yoshio Yazaki
Expression of cytokine mRNAs in murine hearts with acute myocarditis caused by coxsackievirus b3.
The Journal of pathology 1997;183(1):105-8.
1997: Tadashi Yamazaki; Issei Komuro; Yunzeng Zou; Sumiyo Kudoh; T Mizuno; Yukio Hiroi; Ichiro Shiojima; Hiroyuki Takano; Koichiro Kinugawa; Osami Kohmoto; Tokiharu Takahashi; Yoshio Yazaki
Protein kinase A and protein kinase C synergistically activate the Raf-1 kinase/mitogen-activated protein kinase cascade in neonatal rat cardiomyocytes.
Journal of molecular and cellular cardiology 1997;29(9):2491-501.
1997: Hiroko Kadowaki; Yasuhiro Takahashi; A Ando; K Momomura; Yasushi Kaburagi; J D Quin; A C MacCuish; N Koda; Yasushi Fukushima; Simeon I Taylor; Yasuo Akanuma; Yoshio Yazaki; Takashi Kadowaki
Four mutant alleles of the insulin receptor gene associated with genetic syndromes of extreme insulin resistance.
Biochemical and biophysical research communications 1997;237(3):516-20.
1997: Hiroko Kanda; Toshihide Mimura; N Morino; K Hamasaki; Tetsuya Nakamoto; Hisamura Hirai; Chikao Morimoto; Yoshio Yazaki; Yoshihisa Nojima
Ligation of the T cell antigen receptor induces tyrosine phosphorylation of p105CasL, a member of the p130Cas-related docking protein family, and its subsequent binding to the Src homology 2 domain of c-Crk.
European journal of immunology 1997;27(8):2113-7.
1997: Tadashi Yamazaki; Yoshio Yazaki
[Molecular mechanism of cardiac hypertrophy and dysfunction].
Nihon rinsho. Japanese journal of clinical medicine 1997;55(8):1988-93.
1997: Yoshinobu Kanda; Kinuko Mitani; Toshihiro Tanaka; Keiichi Tanaka; Seishi Ogawa; Yoshio Yazaki; Hisamura Hirai
Subcellular localization of the MEN, MLL/MEN and truncated MLL proteins expressed in leukemic cells carrying the t(11;19)(q23;p13.1) translocation.
International journal of hematology 1997;66(2):189-95.
1997: Yasushi Fukushima; Tomoichiro Asano; K Takata; Masako Funaki; Toshio Ogihara; Motonobu Anai; K Tsukuda; Tatsuya Saitoh; Hideki Katagiri; M Aihara; Nobuyuki Matsuhashi; Yoshitaka Oka; Yoshio Yazaki; K Sugano
Role of the C terminus in histamine H2 receptor signaling, desensitization, and agonist-induced internalization.
The Journal of biological chemistry 1997;272(31):19464-70.
1997: Naoto Hirano; Tokiharu Takahashi; T Takahashi; Masahiko Azuma; Ko Okumura; Yoshio Yazaki; Hideo Yagita; Hisamura Hirai
Protective and therapeutic immunity against leukemia induced by irradiated B7-1 (CD80)-transduced leukemic cells.
Human gene therapy 1997;8(11):1375-84.
1997: Jun-ichi Osuga; H Yagyu; Ken Ohashi; Kenji Harada; Yoshio Yazaki; Nobuhiro Yamada; Shun Ishibashi
Effects of apo E deficiency on plasma lipid levels in mice lacking APOBEC-1.
Biochemical and biophysical research communications 1997;236(2):375-8.
1997: N Takahashi; Takashi Kadowaki; Yoshio Yazaki; Yasushi Miyashita; Haruo Kasai
Multiple exocytotic pathways in pancreatic beta cells.
The Journal of cell biology 1997;138(1):55-64.
1997: Kenji Harada; Shun Ishibashi; T Miyashita; Jun-ichi Osuga; H Yagyu; Ken Ohashi; Yoshio Yazaki; Nobuhiro Yamada
Bcl-2 protein inhibits oxysterol-induced apoptosis through suppressing CPP32-mediated pathway.
FEBS letters 1997;411(1):63-6.
1997: Takanari Gotoda; M Kinoshita; Shun Ishibashi; T Inaba; Kenji Harada; M Shimada; Jun-ichi Osuga; T Teramoto; Yoshio Yazaki; Nobuhiro Yamada
Skipping of exon 14 and possible instability of both the mRNA and the resultant truncated protein underlie a common cholesteryl ester transfer protein deficiency in Japan.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(7):1376-81.
1997: M Aikawa; Yasunari Sakomura; M Ueda; Kenjiro Kimura; Ichiro Manabe; Sugao Ishiwata; N Komiyama; H Yamaguchi; Yoshio Yazaki; Ryozo Nagai
Redifferentiation of smooth muscle cells after coronary angioplasty determined via myosin heavy chain expression.
Circulation 1997;96(1):82-90.
1997: Shigeru Chiba; Tokiharu Takahashi; K Takeshita; J Minowada; Yoshio Yazaki; F H Ruddle; Hisamura Hirai
Selective expression of mRNA coding for the truncated form of erythropoietin receptor in hematopoietic cells and its decrease in patients with polycythemia vera.
Blood 1997;90(1):97-104.
1997: Tetsuya Nakamoto; Ryuichi Sakai; Hiroaki Honda; S Ogawa; H Ueno; Takahiro Suzuki; Shin Aizawa; Yoshio Yazaki; Hisamura Hirai
Requirements for localization of p130cas to focal adhesions.
Molecular and cellular biology 1997;17(7):3884-97.
1997: Hiroo Ueno; Hiroaki Honda; Tetsuya Nakamoto; Tetsuya Yamagata; Kazuki Sasaki; Kiyoshi Miyagawa; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
The phosphatidylinositol 3' kinase pathway is required for the survival signal of leukocyte tyrosine kinase.
Oncogene 1997;14(25):3067-72.
1997: Yasushi Fukushima; Tomoichiro Asano; T Saitoh; Motonobu Anai; Masako Funaki; Toshio Ogihara; Hideki Katagiri; Nobuyuki Matsuhashi; Yoshio Yazaki; K Sugano
Oligomer formation of histamine H2 receptors expressed in Sf9 and COS7 cells.
FEBS letters 1997;409(2):283-6.
1997: Hiroyuki Morita; Junichi Taguchi; Hiroki Kurihara; M Kitaoka; H Kaneda; Yukiko Kurihara; Koji Maemura; Takayuki Shindo; T Minamino; Minoru Ohno; K Yamaoki; K Ogasawara; Tadanori Aizawa; Shin Suzuki; Yoshio Yazaki
[Gene Polymorphism of 5, 10-methylenetetrahydrofolate reductase as a coronary risk factor].
Journal of cardiology 1997;29(6):309-15.
1997: Yoshinobu Kanda; Tokiharu Takahashi; Yoichi Imai; K Miyagawa; Nobuya Ohishi; T Oka; Shigeru Chiba; Hisamura Hirai; Yoshio Yazaki
Bronchiolitis obliterans organizing pneumonia after syngeneic bone marrow transplantation for acute lymphoblastic leukemia.
Bone marrow transplantation 1997;19(12):1251-3.
1997: Kinuko Mitani; Akira Hangaishi; Naoko Imamura; K Miyagawa; Seishi Ogawa; Yoshinobu Kanda; Yoshio Yazaki; Hisamura Hirai
No concomitant occurrence of the N-ras and p53 gene mutations in myelodysplastic syndromes.
Leukemia 1997;11(6):863-5.
1997: Hiroaki Honda; Keiya Ozawa; Yoshio Yazaki; Hisamura Hirai
Identification of PU.1 and Sp1 as essential transcriptional factors for the promoter activity of mouse tec gene.
Biochemical and biophysical research communications 1997;234(2):376-81.
1997: Toshio Ogihara; B C Shin; Motonobu Anai; Hideki Katagiri; Kouichi Inukai; Masako Funaki; Yasushi Fukushima; H Ishihara; K Takata; Masatoshi Kikuchi; Yoshio Yazaki; Yoshitaka Oka; Tomoichiro Asano
Insulin receptor substrate (IRS)-2 is dephosphorylated more rapidly than IRS-1 via its association with phosphatidylinositol 3-kinase in skeletal muscle cells.
The Journal of biological chemistry 1997;272(19):12868-73.
1997: Jun-ichi Osuga; Shun Ishibashi; Hitoshi Shimano; T Inaba; M Kawamura; Yoshio Yazaki; Nobuhiro Yamada
Suppression of neutral cholesterol ester hydrolase activity by antisense DNA of hormone-sensitive lipase.
Biochemical and biophysical research communications 1997;233(3):655-7.
1997: Hiroki Kurihara; Yukiko Kurihara; Koji Maemura; Yoshio Yazaki
The role of endothelin-1 in cardiovascular development.
Annals of the New York Academy of Sciences 1997;811():168-76; discussion 176-7.
1997: Hiroyuki Morita; Junichi Taguchi; Hiroki Kurihara; M Kitaoka; H Kaneda; Yukiko Kurihara; Koji Maemura; Takayuki Shindo; T Minamino; Minoru Ohno; K Yamaoki; K Ogasawara; Tadanori Aizawa; Shin Suzuki; Yoshio Yazaki
Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease.
Circulation 1997;95(8):2032-6.
1997: H Odai; Kazuki Sasaki; A Iwamatsu; Tetsuya Nakamoto; Hiroo Ueno; Tetsuya Yamagata; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
Purification and molecular cloning of SH2- and SH3-containing inositol polyphosphate-5-phosphatase, which is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor, erythropoietin, and Bcr-Abl.
Blood 1997;89(8):2745-56.
1997: Naoto Hirano; Tokiharu Takahashi; T Takahashi; Masahiko Azuma; Yoshio Yazaki; Hideo Yagita; Hisamura Hirai
Protective and therapeutic immunity against leukemia induced by irradiated B7-1 (CD80)-transduced leukemic cells.
Leukemia 1997;11 Suppl 3():577-81.
1997: H Odai; Y Hanazono; Kazuki Sasaki; A Iwamatu; Yoshio Yazaki; Hisamura Hirai
The signal transduction through Grb2/Ash in hematopoietic cells.
Leukemia 1997;11 Suppl 3():405-7.
1997: Hisamura Hirai; Seishi Ogawa; Akira Hangaishi; Tokiharu Takahashi; Mineo Kurokawa; Kinuko Mitani; R Ueda; Yoshio Yazaki
Recent progress in molecular mechanisms of leukemogenesis: the cyclin-dependent kinase 4-inhibitor gene in human leukemias.
Leukemia 1997;11 Suppl 3():358-60.
1997: Toshihiro Tanaka; Keiichi Tanaka; Seishi Ogawa; Mineo Kurokawa; Kinuko Mitani; Yoshio Yazaki; Y Shibata; Hisamura Hirai
An acute myeloid leukemia gene, AML1, regulates transcriptional activation and hemopoietic myeloid cell differentiation antagonistically by two alternative spliced forms.
Leukemia 1997;11 Suppl 3():299-302.
1997: Tomoyuki Kuwaki; Hiroki Kurihara; WH Cao; Yukiko Kurihara; M Unekawa; Yoshio Yazaki; Mamoru Kumada
Physiological role of brain endothelin in the central autonomic control: from neuron to knockout mouse.
Progress in neurobiology 1997;51(5):545-79.
1997: H Kim-Motoyama; Kazuki Yasuda; Tokio Yamaguchi; Nobuhiro Yamada; T Katakura; Alan R Shuldiner; Yasuo Akanuma; Y Ohashi; Yoshio Yazaki; Takashi Kadowaki
A mutation of the beta 3-adrenergic receptor is associated with visceral obesity but decreased serum triglyceride.
Diabetologia 1997;40(4):469-72.
1997: Yasuhiro Takahashi; Hiroko Kadowaki; K Momomura; Yasushi Fukushima; T Orban; T Okai; Yuji Taketani; Yasuo Akanuma; Yoshio Yazaki; Takashi Kadowaki
A homozygous kinase-defective mutation in the insulin receptor gene in a patient with leprechaunism.
Diabetologia 1997;40(4):412-20.
1997: Hiroo Ueno; Kazuki Sasaki; Kiyoshi Miyagawa; Hiroaki Honda; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
Antisense repression of proto-oncogene c-Cbl enhances activation of the JAK-STAT pathway but not the ras pathway in epidermal growth factor receptor signaling.
The Journal of biological chemistry 1997;272(13):8739-43.
1997: Kouichi Inukai; Masako Funaki; Toshio Ogihara; Hideki Katagiri; A Kanda; Motonobu Anai; Yasushi Fukushima; T Hosaka; Masato Suzuki; B C Shin; K Takata; Yoshio Yazaki; Masatoshi Kikuchi; Yoshitaka Oka; Tomoichiro Asano
p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin.
The Journal of biological chemistry 1997;272(12):7873-82.
1997: Yoshikazu Shibasaki; H Ishihara; N Kizuki; Tomoichiro Asano; Yoshitaka Oka; Yoshio Yazaki
Massive actin polymerization induced by phosphatidylinositol-4-phosphate 5-kinase in vivo.
The Journal of biological chemistry 1997;272(12):7578-81.
1997: Toshihide Mimura; S Minota; Yoshihisa Nojima; N Morino; K Hamasaki; H Furuya; Yoshio Yazaki
Constitutive tyrosine phosphorylation of the vav proto-oncogene product in MRL/Mp-lpr/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(6):2977-83.
1997: Tadashi Yamazaki; Issei Komuro; Yunzeng Zou; Sumiyo Kudoh; Ichiro Shiojima; Yukio Hiroi; T Mizuno; Ryuichi Aikawa; Hiroyuki Takano; Yoshio Yazaki
Norepinephrine induces the raf-1 kinase/mitogen-activated protein kinase cascade through both alpha 1- and beta-adrenoceptors.
Circulation 1997;95(5):1260-8.
1997: S P Georgescu; Issei Komuro; Yukio Hiroi; T Mizuno; Sumiyo Kudoh; Tadashi Yamazaki; Yoshio Yazaki
Downregulation of polo-like kinase correlates with loss of proliferative ability of cardiac myocytes.
Journal of molecular and cellular cardiology 1997;29(3):929-37.
1997: Yasuo Terauchi; K Iwamoto; H Tamemoto; Kajuro Komeda; Chiaki Ishii; Y Kanazawa; N Asanuma; T Aizawa; Yasuo Akanuma; Kazuki Yasuda; Tatsuhiko Kodama; Kazuyuki Tobe; Yoshio Yazaki; Takashi Kadowaki
Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease.
The Journal of clinical investigation 1997;99(5):861-6.
1997: Akira Hangaishi; Seishi Ogawa; Kinuko Mitani; Noriko Hosoya; Shigeru Chiba; Yoshio Yazaki; Hisamura Hirai
Mutations and loss of expression of a mismatch repair gene, hMLH1, in leukemia and lymphoma cell lines.
Blood 1997;89(5):1740-7.
1997: Noriko Hosoya; K Miyagawa; T Mimura; S Hoshide; H Akazawa; Yoshinobu Kanda; N Takahashi; Hisamura Hirai; Kazuhiko Maekawa; Yoshio Yazaki
Malignant hyperthermia induced by general anesthesia for bone marrow harvesting.
Bone marrow transplantation 1997;19(5):509-11.
1997: Toshihiro Tanaka; Ryozo Nagai; Hitonobu Tomoike; S Takata; K Yano; K Yabuta; N Haneda; O Nakano; A Shibata; T Sawayama; H Kasai; Yoshio Yazaki; Yusuke Nakamura
Four novel KVLQT1 and four novel HERG mutations in familial long-QT syndrome.
Circulation 1997;95(3):565-7.
1997: Hideki Katagiri; Tomoichiro Asano; Kouichi Inukai; Toshio Ogihara; H Ishihara; Yoshikazu Shibasaki; T Murata; J Terasaki; Masatoshi Kikuchi; Yoshio Yazaki; Yoshitaka Oka
Roles of PI 3-kinase and Ras on insulin-stimulated glucose transport in 3T3-L1 adipocytes.
The American journal of physiology 1997;272(2 Pt 1):E326-31.
1997: Yasuhiro Takahashi; Kazuyuki Tobe; Hiroko Kadowaki; D Katsumata; Yasushi Fukushima; Yoshio Yazaki; Yasuo Akanuma; Takashi Kadowaki
Roles of insulin receptor substrate-1 and Shc on insulin-like growth factor I receptor signaling in early passages of cultured human fibroblasts.
Endocrinology 1997;138(2):741-50.
1997: T Minamino; Hiroki Kurihara; M Takahashi; K Shimada; Koji Maemura; H Oda; T Ishikawa; T Uchiyama; K Tanzawa; Yoshio Yazaki
Endothelin-converting enzyme expression in the rat vascular injury model and human coronary atherosclerosis.
Circulation 1997;95(1):221-30.
1997: Toru Oka; Issei Komuro; Ichiro Shiojima; Yukio Hiroi; T Mizuno; Ryuichi Aikawa; Hiroshi Akazawa; T Yamazaki; Yoshio Yazaki
Autoregulation of human cardiac homeobox gene CSX1: mediation by the enhancer element in the first intron.
Heart and vessels 1997;Suppl 12():10-4.
1997: K Hamasaki; Toshihide Mimura; Hiroko Kanda; N Morino; Yoshio Yazaki; Yoshihisa Nojima
Development of systemic lupus erythematosus in a rheumatoid arthritis patient with anti-ribosomal P protein antibody.
Lupus 1997;6(9):734-6.
1997: Sumiyo Kudoh; Issei Komuro; T Mizuno; Tadashi Yamazaki; Yunzeng Zou; Ichiro Shiojima; N Takekoshi; Yoshio Yazaki
Angiotensin II stimulates c-Jun NH2-terminal kinase in cultured cardiac myocytes of neonatal rats.
Circulation research 1997;80(1):139-46.
1995: Takashi Kadowaki; Yasumichi Mori; Shuichi Otabe; H Sakura; Kazuki Yasuda; Yasuo Akanuma; Ryoko Hagura; Hiroko Kadowaki; Yoshio Yazaki
A subtype of diabetes mellitus associated with a mutation in the mitochondrial gene.
Muscle & nerve. Supplement 1995;(3):S137-41.