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Sung Su Yea

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Sung Su Yea; David A Fruman
Achieving cancer cell death with PI3K/mTOR-targeted therapies.
Sung Su Yea; David A Fruman
Cell signaling. New mTOR targets Grb attention.
Mei Hong Li; Gugan Kothandan; Seung Joo Cho; Pham Thi Thu Huong; Yong Hai Nan; Kun Yeong Lee; Song Yub Shin; Sung Su Yea; Young Jin Jeon
Magnolol Inhibits LPS-induced NF-κB/Rel Activation by Blocking p38 Kinase in Murine Macrophages.

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All Publications

2013: Sung Su Yea; David A Fruman
Achieving cancer cell death with PI3K/mTOR-targeted therapies.
Annals of the New York Academy of Sciences 2013;1280():15-8.
2011: Sung Su Yea; David A Fruman
Cell signaling. New mTOR targets Grb attention.
Science (New York, N.Y.) 2011;332(6035):1270-1.
2010: Mei Hong Li; Gugan Kothandan; Seung Joo Cho; Pham Thi Thu Huong; Yong Hai Nan; Kun Yeong Lee; Song Yub Shin; Sung Su Yea; Young Jin Jeon
Magnolol Inhibits LPS-induced NF-κB/Rel Activation by Blocking p38 Kinase in Murine Macrophages.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2010;14(6):353-8.
2010: Won Sun Park; Won-Kyo Jung; Da-Young Lee; Chisook Moon; Sung Su Yea; Sae-Gwang Park; Su-Kil Seo; Cheol Park; Yung Hyun Choi; Gi-Young Kim; Jung Sik Choi; Il-Whan Choi
Cilostazol protects mice against endotoxin shock and attenuates LPS-induced cytokine expression in RAW 264.7 macrophages via MAPK inhibition and NF-kappaB inactivation: not involved in cAMP mechanisms.
International immunopharmacology 2010;10(9):1077-85.
2010: Won-Kyo Jung; Da-Young Lee; Cheol Park; Yung Hyun Choi; Inhak Choi; Sae-Gwang Park; Su-Kil Seo; Soo-Woong Lee; Sung Su Yea; Soon-Cheol Ahn; Chang-Min Lee; Won Sun Park; Jae-Hong Ko; Il-Whan Choi
Cilostazol is anti-inflammatory in BV2 microglial cells by inactivating nuclear factor-kappaB and inhibiting mitogen-activated protein kinases.
British journal of pharmacology 2010;159(6):1274-85.
2010: You Ah Kim; Chang-Suk Kong; Sung Su Yea; Youngwan Seo
Constituents of Corydalis heterocarpa and their anti-proliferative effects on human cancer cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2010;48(2):722-8.
2009: Won-Kyo Jung; Ik-Su Park; Sang-Jun Park; Sung Su Yea; Yung Hyun Choi; Sangtaek Oh; Sae-Gwang Park; Il-Whan Choi
The 15-deoxy-Delta12,14-prostaglandin J2 inhibits LPS-stimulated AKT and NF-kappaB activation and suppresses interleukin-6 in osteoblast-like cells MC3T3E-1.
Life sciences 2009;85(1-2):46-53.
2009: You Ah Kim; Chang-Suk Kong; Young Ran Um; Sun-Young Lim; Sung Su Yea; Youngwan Seo
Evaluation of Salicornia herbacea as a potential antioxidant and anti-inflammatory agent.
Journal of medicinal food 2009;12(3):661-8.
2009: Won-Kyo Jung; Young-Wook Ahn; Sang-Hoon Lee; Yung Hyun Choi; Se-Kwon Kim; Sung Su Yea; Inhak Choi; Sae-Gwang Park; Su-Kil Seo; Soo-Woong Lee; Il-Whan Choi
Ecklonia cava ethanolic extracts inhibit lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in BV2 microglia via the MAP kinase and NF-kappaB pathways.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2009;47(2):410-7.
2008: Ki-Sun Kim; Sangtaek Oh; Sung Su Yea; Moon-Young Yoon; Dong-Eun Kim
Amplification of an RNA ligase ribozyme under alternating temperature conditions.
FEBS letters 2008;582(18):2745-52.
2008: Se-Kwon Kim; Da-Young Lee; Won-Kyo Jung; Ji-Hye Kim; Inhak Choi; Sae-Gwang Park; Su-Kil Seo; Soo-Woong Lee; Chang Min Lee; Sung Su Yea; Yung Hyun Choi; Il-Whan Choi
Effects of Ecklonia cava ethanolic extracts on airway hyperresponsiveness and inflammation in a murine asthma model: role of suppressor of cytokine signaling.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2008;62(5):289-96.
2008: Won-Kyo Jung; Da-Young Lee; Yung Hyun Choi; Sung Su Yea; Inhak Choi; Sae-Gwang Park; Su K Seo; Soo-Woong Lee; Chang-Min Lee; Se-Kwon Kim; You-Jin Jeon; Il-Whan Choi
Caffeic acid phenethyl ester attenuates allergic airway inflammation and hyperresponsiveness in murine model of ovalbumin-induced asthma.
Life sciences 2008;82(13-14):797-805.
2008: Munju Cho; Seoyoung Park; Jungsug Gwak; Dong-Eun Kim; Sung Su Yea; Jae-Gook Shin; Sangtaek Oh
Bisindoylmaleimide I suppresses adipocyte differentiation through stabilization of intracellular beta-catenin protein.
Biochemical and biophysical research communications 2008;367(1):195-200.
2008: Sung Su Yea; Sang Seop Lee; Woo-Young Kim; Kwang-Hyeon Liu; Hyojin Kim; Ji-Hong Shon; In-June Cha; Jae-Gook Shin
Genetic variations and haplotypes of UDP-glucuronosyltransferase 1A locus in a Korean population.
Therapeutic drug monitoring 2008;30(1):23-34.
2008: Won-Kyo Jung; Inhak Choi; Da-Young Lee; Sung Su Yea; Yung Hyun Choi; Moon-Moo Kim; Sae-Gwang Park; Su-Kil Seo; Soo-Woong Lee; Chang-Min Lee; Yeong-Min Park; Il-Whan Choi
Caffeic acid phenethyl ester protects mice from lethal endotoxin shock and inhibits lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW 264.7 macrophages via the p38/ERK and NF-kappaB pathways.
The international journal of biochemistry & cell biology 2008;40(11):2572-82.
2008: Sae-Gwang Park; Da-Young Lee; Su K Seo; Soo-Woong Lee; Se-Kwon Kim; Won-Kyo Jung; Mi-Seon Kang; Yung Hyun Choi; Sung Su Yea; Inhak Choi; Il-Whan Choi
Evaluation of anti-allergic properties of caffeic acid phenethyl ester in a murine model of systemic anaphylaxis.
Toxicology and applied pharmacology 2008;226(1):22-9.
2007: Chun Yeon Choi; Kyung-Ran Park; Jung-Hee Lee; Young Jin Jeon; Kwang-Hyeon Liu; Sangtaek Oh; Dong-Eun Kim; Sung Su Yea
Isoeugenol suppression of inducible nitric oxide synthase expression is mediated by down-regulation of NF-kappaB, ERK1/2, and p38 kinase.
European journal of pharmacology 2007;576(1-3):151-9.
2007: Kyung-Ran Park; Jung-Hee Lee; ChunYeon Choi; Kwang-Hyeon Liu; Dae-Hyun Seog; Yong-Ho Kim; Dong-Eun Kim; Chul-Ho Yun; Sung Su Yea
Suppression of interleukin-2 gene expression by isoeugenol is mediated through down-regulation of NF-AT and NF-kappaB.
International immunopharmacology 2007;7(9):1251-8.
2007: Ki-Sun Kim; Woo-Hyung Choi; Bo-Ra Choi; Sangtaek Oh; Sung Su Yea; Moon-Young Yoon; Dong-Eun Kim
Replication of an RNA ligase ribozyme under alternating temperature condition.
FEBS letters 2007;581(21):4065-72.
2006: Seong Kook Park; Kyung Wook Heo; Hyun Jung; Sung Su Yea; Young-Il Yang
Expression of cyclooxygenase-2 and 5-lipoxygenase in nasal polyps associated with interleukin-4 promoter polymorphism -590.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2006;135(6):928-32.
2006: Sung Su Yea; Haeng-Soon Jeong; Chun Yeon Choi; Kyung-Ran Park; Sangtaek Oh; Jae-Gook Shin; Chul-Ho Yun
Inhibitory effect of anethole on T-lymphocyte proliferation and interleukin-2 production through down-regulation of the NF-AT and AP-1.
Toxicology in vitro : an international journal published in association with BIBRA 2006;20(7):1098-105.
2006: Sung Su Yea; Young-Il Yang; Seong Kook Park; Won Hee Jang; Sang Seop Lee; Dae-Hyun Seog; Yeong-Hong Park; Jin Ho Chun
Interleukin-4 C-590T polymorphism is associated with protection against nasal polyps in a Korean population.
American journal of rhinology 2006;20(5):550-3.
2006: Hyun Mi Ryu; Sung Gyoo Park; Sung Su Yea; Won Hee Jang; Young-Il Yang; Guhung Jung
Gene expression analysis of primary normal human hepatocytes infected with human hepatitis B virus.
World journal of gastroenterology : WJG 2006;12(31):4986-95.
2006: Hyojin Kim; Suil Kang; Hyunmi Kim; Yune-Jung Yoon; Eun-Young Cha; Hye Suk Lee; Jeong-Han Kim; Sung Su Yea; Sang-Seop Lee; Jae-Gook Shin; Kwang-Hyeon Liu
In vitro metabolism of a new cardioprotective agent, KR-32570, in human liver microsomes.
Rapid communications in mass spectrometry : RCM 2006;20(5):837-43.
2005: Munju Cho; Jungsug Gwak; Seoyoung Park; Jaejoon Won; Dong-Eun Kim; Sung Su Yea; In-June Cha; Tae Kook Kim; Jae-Gook Shin; Sangtaek Oh
Diclofenac attenuates Wnt/beta-catenin signaling in colon cancer cells by activation of NF-kappaB.
FEBS letters 2005;579(20):4213-8.
2005: Sang Seop Lee; So-Young Kim; Woo-Young Kim; Huong Thi-Le; Young-Ran Yoon; Sung Su Yea; Jae-Gook Shin
MDR1 genetic polymorphisms and comparison of MDR1 haplotype profiles in Korean and Vietnamese populations.
Therapeutic drug monitoring 2005;27(4):531-5.
2005: Barbara L F Kaplan; Yanli Ouyang; Amy Herring; Sung Su Yea; Raj Razdan; Norbert E Kaminski
Inhibition of leukocyte function and interleukin-2 gene expression by 2-methylarachidonyl-(2'-fluoroethyl)amide, a stable congener of the endogenous cannabinoid receptor ligand anandamide.
Toxicology and applied pharmacology 2005;205(2):107-15.
2005: Sang Seop Lee; Kang Mi Kim; Huong Thi-Le; Sung Su Yea; In-June Cha; Jae-Gook Shin
Genetic polymorphism of CYP2C9 in a Vietnamese Kinh population.
Therapeutic drug monitoring 2005;27(2):208-10.
2003: Chul-Ho Yun; Hye Suk Lee; Hee-Yong Lee; Sung-Kun Yim; Keon-Hee Kim; Eunhee Kim; Sung Su Yea; F Peter Guengerich
Roles of human liver cytochrome P450 3A4 and 1A2 enzymes in the oxidation of myristicin.
Toxicology letters 2003;137(3):143-50.
2001: Sung Su Yea; Young-Il Yang; Won Hee Jang; Yong Jae Lee; H S Bae; KH Paik
Association between TNF-alpha promoter polymorphism and Helicobacter pylori cagA subtype infection.
Journal of clinical pathology 2001;54(9):703-6.
2001: Sung Su Yea; H M Kim; Hee-Mock Oh; KH Paik; Kyu-Hwan Yang
Microcystin-induced down-regulation of lymphocyte functions through reduced IL-2 mRNA stability.
Toxicology letters 2001;122(1):21-31.
2001: Won Hee Jang; Young-Il Yang; Sung Su Yea; Yong Jae Lee; J H Chun; H I Kim; M S Kim; KH Paik
The -238 tumor necrosis factor-alpha promoter polymorphism is associated with decreased susceptibility to cancers.
Cancer letters 2001;166(1):41-6.
2000: Sung Su Yea; H M Kim; Young Jin Jeon; Hee-Mock Oh; H G Jeong; Kyu-Hwan Yang
Suppression of IL-2 and IL-4 gene expression by nodularin through the reduced NF-AT binding activity.
Toxicology letters 2000;114(1-3):215-24.
2000: Sung Su Yea; Kyu-Hwan Yang; Norbert E Kaminski
Role of nuclear factor of activated T-cells and activator protein-1 in the inhibition of interleukin-2 gene transcription by cannabinol in EL4 T-cells.
The Journal of pharmacology and experimental therapeutics 2000;292(2):597-605.
1999: SH Han; Young Jin Jeon; Sung Su Yea; Kyu-Hwan Yang
Suppression of the interleukin-2 gene expression by aflatoxin B1 is mediated through the down-regulation of the NF-AT and AP-1 transcription factors.
Toxicology letters 1999;108(1):1-10.
1998: S H Han; Sung Su Yea; Young Jin Jeon; Kyu-Hwan Yang; Norbert E Kaminski
Transforming growth factor-beta 1 (TGF-beta1) promotes IL-2 mRNA expression through the up-regulation of NF-kappaB, AP-1 and NF-AT in EL4 cells.
The Journal of pharmacology and experimental therapeutics 1998;287(3):1105-12.
1998: Young Jin Jeon; S H Han; Y W Lee; Sung Su Yea; Kyu-Hwan Yang
Inhibition of NF-kappa B/Rel nuclear translocation by dexamethasone: mechanism for the inhibition of iNOS gene expression.
Biochemistry and molecular biology international 1998;45(3):435-41.