Andrew Yen

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Smith James; Bunaciu Rodica P; Reiterer Gudrun; Coder David; George Thaddeus; Asaly Michael; Yen Andrew
Retinoic acid induces nuclear accumulation of Raf1 during differentiation of HL-60 cells.
Tallini Yvonne N; Greene Kai Su; Craven Michael; Spealman Alyson; Breitbach Martin; Smith James; Fisher Patricia J; Steffey Michele; Hesse Michael; Doran Robert M; Woods Ashley; Singh Babu; Yen Andrew; Fleischmann Bernd K; Kotlikoff Michael I
c-kit expression identifies cardiovascular precursors in the neonatal heart.
Shen Miaoqing; Yen Andrew
Nicotinamide cooperates with retinoic acid and 1,25-dihydroxyvitamin D(3) to regulate cell differentiation and cell cycle arrest of human myeloblastic leukemia cells.

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All Publications

2009: Smith James; Bunaciu Rodica P; Reiterer Gudrun; Coder David; George Thaddeus; Asaly Michael; Yen Andrew
Retinoic acid induces nuclear accumulation of Raf1 during differentiation of HL-60 cells.
Experimental cell research 2009;315(13):2241-8.
2009: Tallini Yvonne N; Greene Kai Su; Craven Michael; Spealman Alyson; Breitbach Martin; Smith James; Fisher Patricia J; Steffey Michele; Hesse Michael; Doran Robert M; Woods Ashley; Singh Babu; Yen Andrew; Fleischmann Bernd K; Kotlikoff Michael I
c-kit expression identifies cardiovascular precursors in the neonatal heart.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(6):1808-13.
2009: Shen Miaoqing; Yen Andrew
Nicotinamide cooperates with retinoic acid and 1,25-dihydroxyvitamin D(3) to regulate cell differentiation and cell cycle arrest of human myeloblastic leukemia cells.
Oncology 2009;76(2):91-100.
2008: Shen Miaoqing; Yen Andrew
c-Cbl interacts with CD38 and promotes retinoic acid-induced differentiation and G0 arrest of human myeloblastic leukemia cells.
Cancer research 2008;68(21):8761-9.
2008: Kauss M Ariel; Reiterer Gudrun; Bunaciu Rodica P; Yen Andrew
Human myeloblastic leukemia cells (HL-60) express a membrane receptor for estrogen that signals and modulates retinoic acid-induced cell differentiation.
Experimental cell research 2008;314(16):2999-3006.
2008: Reiterer Gudrun; Bunaciu Rodica P; Smith James L; Yen Andrew
Inhibiting the platelet derived growth factor receptor increases signs of retinoic acid syndrome in myeloid differentiated HL-60 cells.
FEBS letters 2008;582(17):2508-14.
2008: Squyres S W; Arvidson R E; Ruff S; Gellert R; Morris R V; Ming D W; Crumpler L; Farmer J D; Marais D J Des; Yen A; McLennan S M; Calvin W; Bell J F; Clark B C; Wang A; McCoy T J; Schmidt M E; de Souza P A
Detection of silica-rich deposits on Mars.
Science (New York, N.Y.) 2008;320(5879):1063-7.
2008: Wang Jianrong; Yen Andrew
A MAPK-positive feedback mechanism for BLR1 signaling propels retinoic acid-triggered differentiation and cell cycle arrest.
The Journal of biological chemistry 2008;283(7):4375-86.
2007: Reiterer Gudrun; Yen Andrew
Platelet-derived growth factor receptor regulates myeloid and monocytic differentiation of HL-60 cells.
Cancer research 2007;67(16):7765-72.
2006: Reiterer Gudrun; Yen Andrew
Inhibition of the janus kinase family increases extracellular signal-regulated kinase 1/2 phosphorylation and causes endoreduplication.
Cancer research 2006;66(18):9083-9.
2006: Lamkin Thomas J; Chin Vivian; Yen Andrew
All-trans retinoic acid induces p62DOK1 and p56DOK2 expression which enhances induced differentiation and G0 arrest of HL-60 leukemia cells.
American journal of hematology 2006;81(8):603-15.
2006: Lamkin Thomas J; Chin Vivian; Varvayanis Susi; Smith James L; Sramkoski R Michael; Jacobberger James W; Yen Andrew
Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels.
Journal of cellular biochemistry 2006;97(6):1328-38.
2006: Yen Andrew; Varvayanis Susi; Smith James L; Lamkin Thomas J
Retinoic acid induces expression of SLP-76: expression with c-FMS enhances ERK activation and retinoic acid-induced differentiation/G0 arrest of HL-60 cells.
European journal of cell biology 2006;85(2):117-32.
2004: Flaminio M Julia B F; Yen Andrew; Antczak Douglas F
The proliferation inhibitory proteins p27(Kip1) and retinoblastoma are involved in the control of equine lymphocyte proliferation.
Veterinary immunology and immunopathology 2004;102(4):363-77.
2004: Yen Andrew; Fenning Robert; Chandraratna Roshantha; Walker Patricia; Varvayanis Susi
A retinoic acid receptor beta/gamma-selective prodrug (tazarotene) plus a retinoid X receptor ligand induces extracellular signal-regulated kinase activation, retinoblastoma hypophosphorylation, G0 arrest, and cell differentiation.
Molecular pharmacology 2004;66(6):1727-37.
2004: Yen Andrew; Lin David M; Lamkin Thomas J; Varvayanis Susi
retinoic acid, bromodeoxyuridine, and the Delta 205 mutant polyoma virus middle T antigen regulate expression levels of a common ensemble of proteins associated with early stages of inducing HL-60 leukemic cell differentiation.
In vitro cellular & developmental biology. Animal 2004;40(7):216-41.
2004: Wang Jianrong; Yen Andrew
A novel retinoic acid-responsive element regulates retinoic acid-induced BLR1 expression.
Molecular and cellular biology 2004;24(6):2423-43.
2002: Battle Traci E; Yen Andrew
Ectopic expression of CXCR5/BLR1 accelerates retinoic acid- and vitamin D(3)-induced monocytic differentiation of U937 cells.
Experimental biology and medicine (Maywood, N.J.) 2002;227(9):753-62.
2002: Wightman Jenifer; Roberson Mark S; Lamkin Thomas J; Varvayanis Susi; Yen Andrew
Retinoic acid-induced growth arrest and differentiation: retinoic acid up-regulates CD32 (Fc gammaRII) expression, the ectopic expression of which retards the cell cycle.
Molecular cancer therapeutics 2002;1(7):493-506.
2001: Hong H Y; Varvayanis S; Yen A
Retinoic acid causes MEK-dependent RAF phosphorylation through RARalpha plus RXR activation in HL-60 cells.
Differentiation; research in biological diversity 2001;68(1):55-66.
2001: Yen A; Placanica L; Bloom S; Varvayanis S
Polyomavirus small t antigen prevents retinoic acid-induced retinoblastoma protein hypophosphorylation and redirects retinoic acid-induced G0 arrest and differentiation to apoptosis.
Journal of virology 2001;75(11):5302-14.
2001: Yen A; Norman A W; Varvayanis S
Nongenomic vitamin D3 analogs activating ERK2 in HL-60 cells show that retinoic acid-induced differentiation and cell cycle arrest require early concurrent MAPK and RAR and RXR activation.
In vitro cellular & developmental biology. Animal 2001;37(2):93-9.
2001: Battle T E; Roberson M S; Zhang T; Varvayanis S; Yen A
Retinoic acid-induced blr1 expression requires RARalpha, RXR, and MAPK activation and uses ERK2 but not JNK/SAPK to accelerate cell differentiation.
European journal of cell biology 2001;80(1):59-67.
2000: Yen A; Varvayanis S
Retinoic acid increases amount of phosphorylated RAF; ectopic expression of cFMS reveals that retinoic acid-induced differentiation is more strongly dependent on ERK2 signaling than induced GO arrest is.
In vitro cellular & developmental biology. Animal 2000;36(4):249-55.
2000: Battle T E; Levine R A; Yen A
Retinoic acid-induced blr1 expression promotes ERK2 activation and cell differentiation in HL-60 cells.
Experimental cell research 2000;254(2):287-98.
1999: Yen A; Roberson M S; Varvayanis S
Retinoic acid selectively activates the ERK2 but not JNK/SAPK or p38 MAP kinases when inducing myeloid differentiation.
In vitro cellular & developmental biology. Animal 1999;35(9):527-32.
1999: Yen A; Cherington V; Schaffhausen B; Marks K; Varvayanis S
Transformation-defective polyoma middle T antigen mutants defective in PLCgamma, PI-3, or src kinase activation enhance ERK2 activation and promote retinoic acid-induced, cell differentiation like wild-type middle T.
Experimental cell research 1999;248(2):538-51.
1998: Yen A; Roberson M S; Varvayanis S; Lee A T
Retinoic acid induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest.
Cancer research 1998;58(14):3163-72.
1998: Yen A; Sturgill R
Hypophosphorylation of the RB protein in S and G2 as well as G1 during growth arrest.
Experimental cell research 1998;241(2):324-31.
1998: Platko J D; Forbes M E; Varvayanis S; Williams M N; Brooks S C; Cherington V; Yen A
Polyoma middle T antigen in HL-60 cells accelerates hematopoietic myeloid and monocytic cell differentiation.
Experimental cell research 1998;238(1):42-50.
1997: Brooks S C; Sturgill R; Choi J; Yen A
An RXR-selective analog attenuates the RAR alpha-selective analog-induced differentiation and non-G1-restricted growth arrest of NB4 cells.
Experimental cell research 1997;234(2):259-69.
1997: Yen A; Sturgill R; Varvayanis S
Increasing c-FMS (CSF-1 receptor) expression decreases retinoic acid concentration needed to cause cell differentiation and retinoblastoma protein hypophosphorylation.
Cancer research 1997;57(10):2020-8.
1997: Yen A; Coder D; Varvayanis S
Concentration of RB protein in nucleus vs. cytoplasm is stable as phosphorylation of RB changes during the cell cycle and differentiation.
European journal of cell biology 1997;72(2):159-65.
1997: Platko J D; Yen A
Paxillin increases as retinoic acid or vitamin D3 induce HL-60 cell differentiation.
In vitro cellular & developmental biology. Animal 1997;33(2):84-7.
1996: Yen A; Sturgill R; Varvayanis S; Chern R
FMS (CSF-1 receptor) prolongs cell cycle and promotes retinoic acid-induced hypophosphorylation of retinoblastoma protein, G1 arrest, and cell differentiation.
Experimental cell research 1996;229(1):111-25.
1996: Yen A; Soong S
Retinoic acid-induced RB (retinoblastoma) hypophosphorylation enhanced by CGP 52411 (4,5-dianilinophthalimide), an EGF family tyrosine kinase receptor inhibitor.
European journal of cell biology 1996;69(4):327-34.
1996: Brooks S C; Kazmer S; Levin A A; Yen A
Myeloid differentiation and retinoblastoma phosphorylation changes in HL-60 cells induced by retinoic acid receptor- and retinoid X receptor-selective retinoic acid analogs.
Blood 1996;87(1):227-37.
1995: Yen A; Varvayanis S
The ratio of retinoblastoma (RB) to fos and RB to myc expression during the cell cycle.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1995;210(3):205-12.
1995: Yen A; Varvayanis S
RB phosphorylation in sodium butyrate-resistant HL-60 cells: cross-resistance to retinoic acid but not vitamin D3.
Journal of cellular physiology 1995;163(3):502-9.
1994: Yen A; Williams M; Platko J D; Der C; Hisaka M
Expression of activated RAF accelerates cell differentiation and RB protein down-regulation but not hypophosphorylation.
European journal of cell biology 1994;65(1):103-13.
1994: Yen A; Varvayanis S
Late dephosphorylation of the RB protein in G2 during the process of induced cell differentiation.
Experimental cell research 1994;214(1):250-7.
1994: Yen A; Soong S; Kwon H J; Yoshida M; Beppu T; Varvayanis S
Enhanced cell differentiation when RB is hypophosphorylated and down-regulated by radicicol, a SRC-kinase inhibitor.
Experimental cell research 1994;214(1):163-71.
1994: Yen A; French T; Russell K; Varvayanis S; Forbes M
Vitamin-regulated retinoblastoma tumor suppressor gene expression in leukemic cells.
Advances in experimental medicine and biology 1994;354():1-18.
1993: Yen A; Forbes M E; Varvayanis S; Tykocinski M L; Groger R K; Platko J D
C-FMS dependent HL-60 cell differentiation and regulation of RB gene expression.
Journal of cellular physiology 1993;157(2):379-91.
1993: Yen A; Varvayanis S; Platko J D
12-O-tetradecanoylphorbol-13-acetate and staurosporine induce increased retinoblastoma tumor suppressor gene expression with megakaryocytic differentiation of leukemic cells.
Cancer research 1993;53(13):3085-91.
1992: Yen A; Samuel V; Forbes M
Regulation of cell proliferation: late down-regulation of c-myb preceding myelo-monocytic cell differentiation.
Journal of cellular physiology 1992;153(1):147-56.
1992: Yen A; Varvayanis S
RB tumor suppressor gene expression responds to DNA synthesis inhibitors.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1992;28A(9-10):669-72.
1992: Yen A; Chandler S; Forbes M E; Fung Y K; T'Ang A; Pearson R
Coupled down-regulation of the RB retinoblastoma and c-myc genes antecedes cell differentiation: possible role of RB as a "status quo" gene.
European journal of cell biology 1992;57(2):210-21.
1992: Yen A; Chandler S
Inducers of leukemic cell differentiation cause down-regulation of RB gene expression.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1992;199(3):291-7.
1991: Yen A; Chandler S; Sturzenegger-Varvayanis S
Regulated expression of the RB "tumor suppressor gene" in normal lymphocyte mitogenesis: elevated expression in transformed leukocytes and role as a "status quo" gene.
Experimental cell research 1991;192(1):289-97.
1990: Yen A; Forbes M E
c-myc down regulation and precommitment in HL-60 cells due to bromodeoxyuridine.
Cancer research 1990;50(5):1411-20.
1989: Mihara K; Cao X R; Yen A; Chandler S; Driscoll B; Murphree A L; T'Ang A; Fung Y K
Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product.
Science (New York, N.Y.) 1989;246(4935):1300-3.

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