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Giles Yeo

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Physiology

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Singapore

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TOP 3
Giles S H Yeo; C Choi
Comment on authors' reply: patients' perception of risk: informed choice in prenatal testing for foetal aneuploidy.
Pawan Gulati; Heather P Harding; Paul J Lehner; Marcella Ma; Stephen O'Rahilly; Debra Rimmington; David Ron; Yi-Chun Loraine Tung; Robin Antrobus; Frances M Ashcroft; Man Ka Cheung; Chris D Church; Anthony P Coll; Roger D Cox; Giles S H Yeo
Role for the obesity-related FTO gene in the cellular sensing of amino acids.
Fiona McMurray; George Nicholson; Stephen O'Rahilly; Debra Rimmington; Lydia Teboul; Y C Loraine Tung; Sara Wells; Giles S H Yeo; Frances M Ashcroft; Fatima Bosch; Chris D Church; Anthony P Coll; Veronica Jimenez; Rachel Larder; Roger D Cox
Adult onset global loss of the fto gene alters body composition and metabolism in the mouse.

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All Publications

2013: Giles S H Yeo; C Choi
Comment on authors' reply: patients' perception of risk: informed choice in prenatal testing for foetal aneuploidy.
Singapore medical journal 2013;54(4):237-8.
2013: Pawan Gulati; Heather P Harding; Paul J Lehner; Marcella Ma; Stephen O'Rahilly; Debra Rimmington; David Ron; Yi-Chun Loraine Tung; Robin Antrobus; Frances M Ashcroft; Man Ka Cheung; Chris D Church; Anthony P Coll; Roger D Cox; Giles S H Yeo
Role for the obesity-related FTO gene in the cellular sensing of amino acids.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(7):2557-62.
2013: Fiona McMurray; George Nicholson; Stephen O'Rahilly; Debra Rimmington; Lydia Teboul; Y C Loraine Tung; Sara Wells; Giles S H Yeo; Frances M Ashcroft; Fatima Bosch; Chris D Church; Anthony P Coll; Veronica Jimenez; Rachel Larder; Roger D Cox
Adult onset global loss of the fto gene alters body composition and metabolism in the mouse.
PLoS genetics 2013;9(1):e1003166.
2012: Giles S H Yeo; Christina Choi
Comment on: patients' perception of risk: informed choice in prenatal testing for foetal aneuploidy.
Singapore medical journal 2012;53(12):853-4; author's reply p. 854.
2012: Ester Zito; Giles S H Yeo; Junichi Fujii; Henning Gram Hansen; David Ron
Endoplasmic reticulum thiol oxidase deficiency leads to ascorbic acid depletion and noncanonical scurvy in mice.
Molecular cell 2012;48(1):39-51.
2012: Tuntas Dhanardhono; Fanti Saktini; Xing Wei; Puspita Kusuma Dewi; Edwin Thia; Giles S H Yeo
Incidence and outcome of prenatally diagnosed, chromosomally normal congenital heart defects in Singapore.
Singapore medical journal 2012;53(10):643-7.
2012: Giles S H Yeo; Lora K Heisler
Unraveling the brain regulation of appetite: lessons from genetics.
Nature neuroscience 2012;15(10):1343-9.
2012: Abdella M Habib; Tom C E Morley; Helen E Parker; Frank Reimann; Paul Richards; Gareth J Rogers; Giles S H Yeo; Christopher A M Bannon; Lynne S Cairns; Fiona M Gribble
Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry.
Endocrinology 2012;153(7):3054-65.
2012: Marcella Ma; Stephen O'Rahilly; David Ron; Heather P Harding; Giles S H Yeo
Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate.
The Biochemical journal 2012;444(2):183-7.
2012: Giles S H Yeo
FTO and obesity: a problem for a billion people.
Journal of neuroendocrinology 2012;24(2):393-4.
2011: Xiaoye Shan; Giles S H Yeo
Central leptin and ghrelin signalling: comparing and contrasting their mechanisms of action in the brain.
Reviews in endocrine & metabolic disorders 2011;12(3):197-209.
2011: Giles S H Yeo
Where next for GWAS?
Briefings in functional genomics 2011;10(2):51.
2011: Yi-Chun Loraine Tung; Giles S H Yeo
From GWAS to biology: lessons from FTO.
Annals of the New York Academy of Sciences 2011;1220():162-71.
2011: Rachel Larder; M K Marcella Cheung; Y C Loraine Tung; Giles S H Yeo; Anthony P Coll
Where to go with FTO?
Trends in endocrinology and metabolism: TEM 2011;22(2):53-9.
2011: Man-Ka Marcella Cheung; Giles S H Yeo
FTO Biology and Obesity: Why Do a Billion of Us Weigh 3 kg More?
Frontiers in endocrinology 2011;2():4.
2011: Laura F Gumy; Giles S H Yeo; Yi-Chun Loraine Tung; Krishna H Zivraj; Dianna Willis; Giovanni Coppola; Brian Y H Lam; Jeffery L Twiss; Christine E Holt; James W Fawcett
Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization.
RNA (New York, N.Y.) 2011;17(1):85-98.
2010: Krishna H Zivraj; Yi Chun Loraine Tung; Michael Piper; Laura Gumy; James W Fawcett; Giles S H Yeo; Christine E Holt
Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(46):15464-78.
2010: Jian-Hua Chen; Jane L Tarry-Adkins; Kieran Matharu; Giles S H Yeo; Susan E Ozanne
Maternal protein restriction affects gene expression profiles in the kidney at weaning with implications for the regulation of renal function and lifespan.
Clinical science (London, England : 1979) 2010;119(9):373-84.
2010: Zorica Jovanovic; Giles S H Yeo
Central leptin signalling: beyond the arcuate nucleus.
Autonomic neuroscience : basic & clinical 2010;156(1-2):8-14.
2010: Yi-Chun Loraine Tung; Giles S H Yeo
Central melanocortin signaling regulates cholesterol.
Nature neuroscience 2010;13(7):779-80.
2010: Yi-Chun Loraine Tung; Eduard Ayuso; Xiaoye Shan; Fatima Bosch; Stephen O'Rahilly; Anthony P Coll; Giles S H Yeo
Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats.
PloS one 2010;5(1):e8771.
2010: David Meyre; Karine Proulx; Hiroko Kawagoe-Takaki; Vincent Vatin; Ruth Gutiérrez-Aguilar; Debbie Lyon; Marcella Ma; Hélène Choquet; Fritz F Horber; Wim Van Hul; Luc Van Gaal; Beverley Balkau; Sophie Visvikis-Siest; François Pattou; I Sadaf Farooqi; Vladimir Saudek; Stephen O'Rahilly; philippe froguel; Barbara Sedgwick; Giles S H Yeo
Prevalence of loss-of-function FTO mutations in lean and obese individuals.
Diabetes 2010;59(1):311-8.
2009: Adam J de Smith; Carolin Purmann; Robin G Walters; Richard J Ellis; Susan E Holder; Mieke M van Haelst; Angela F Brady; Una L Fairbrother; Mehul Dattani; Julia M Keogh; Elana Henning; Giles S H Yeo; Stephen O'Rahilly; philippe froguel; I Sadaf Farooqi; Alexandra I F Blakemore
A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism.
Human molecular genetics 2009;18(17):3257-65.
2009: Sarah Boissel; Orit Reish; Karine Proulx; Hiroko Kawagoe-Takaki; Barbara Sedgwick; Giles S H Yeo; David Meyre; Christelle Golzio; Florence Molinari; Noman Kadhom; Heather C Etchevers; Vladimir Saudek; I Sadaf Farooqi; philippe froguel; Tomas Lindahl; Stephen O'Rahilly; Arnold Munnich; Laurence Colleaux
Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations.
American journal of human genetics 2009;85(1):106-11.
2009: J Mohd; J Tan; Giles S H Yeo
Management of foetal hydrops secondary to Kell isoimmunisation via foetal blood transfusion: a Doppler-guided approach.
Singapore medical journal 2009;50(4):e143-6.
2009: Karen Tan; Irina D Pogozheva; Giles S H Yeo; Dirk Hadaschik; Julia M Keogh; Carrie Haskell-Leuvano; Stephen O'Rahilly; Henry I Mosberg; I Sadaf Farooqi
Functional characterization and structural modeling of obesity associated mutations in the melanocortin 4 receptor.
Endocrinology 2009;150(1):114-25.
2008: Y C Loraine Tung; Marcella Ma; Sarah Piper; Anthony Coll; Stephen O'Rahilly; Giles S H Yeo
Novel leptin-regulated genes revealed by transcriptional profiling of the hypothalamic paraventricular nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(47):12419-26.
2008: Anthony P Coll; Giles S H Yeo; I Sadaf Farooqi; Stephen O'Rahilly
SnapShot: the hormonal control of food intake.
Cell 2008;135(3):572.e1-2.
2008: K B L Tan; KH Tan; Giles S H Yeo
Cleft deformities in Singapore: a population-based series 1993-2002.
Singapore medical journal 2008;49(9):710-4.
2008: Daniel Lam; Magdalena J Przydzial; Simon H Ridley; Giles S H Yeo; Justin J Rochford; Stephen O'Rahilly; Lora K Heisler
Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors.
Endocrinology 2008;149(3):1323-8.
2008: K B Tan; KH Tan; S K Chew; Giles S H Yeo
Gastroschisis and omphalocele in Singapore: a ten-year series from 1993 to 2002.
Singapore medical journal 2008;49(1):31-6.
2007: Thomas Gerken; Christophe A Girard; Yi-Chun Loraine Tung; Celia J Webby; Vladimir Saudek; Kirsty S Hewitson; Giles S H Yeo; Michael McDonough; Sharon Cunliffe; Luke A McNeill; Juris Galvanovskis; Patrik Rorsman; Peter Robins; Xavier Prieur; Anthony P Coll; Marcella Ma; Zorica Jovanovic; I Sadaf Farooqi; Barbara Sedgwick; Inês Barroso; Tomas Lindahl; Chris P Ponting; Frances M Ashcroft; Stephen O'Rahilly; Christopher J Schofield
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase.
Science (New York, N.Y.) 2007;318(5855):1469-72.
2007: K Loi; C K Khoo; KH Tan; Giles S H Yeo; Kenneth Kwek
A review of 93 cases of severe preeclampsia in Singapore: are there risk factors for complications?
Singapore medical journal 2007;48(9):808-12.
2007: A Oswal; Giles S H Yeo
The leptin melanocortin pathway and the control of body weight: lessons from human and murine genetics.
Obesity reviews : an official journal of the International Association for the Study of Obesity 2007;8(4):293-306.
2007: Lora K Heisler; Nina Pronchuk; Katsunori Nonogaki; Ligang Zhou; Jacob Raber; Loraine Tung; Giles S H Yeo; Stephen O'Rahilly; William F Colmers; Joel K Elmquist; Laurence H Tecott
Serotonin activates the hypothalamic-pituitary-adrenal axis via serotonin 2C receptor stimulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(26):6956-64.
2007: Hua-Sieng Ting; Pui-See Chin; Giles S H Yeo; Kenneth Kwek
Comparison of bedside test kits for prediction of preterm delivery: phosphorylated insulin-like growth factor binding protein-1 (pIGFBP-1) test and fetal fibronectin test.
Annals of the Academy of Medicine, Singapore 2007;36(6):399-402.
2007: Gema Medina-Gomez; Sarah L Gray; Laxman Yetukuri; Kenju Shimomura; Sam Virtue; Mark Campbell; R Keira Curtis; Mercedes Jimenez-Linan; Margaret Blount; Giles S H Yeo; Miguel Lopez; Tuulikki Seppänen-Laakso; Frances M Ashcroft; Matej Oresic; Antonio Vidal-Puig
PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.
PLoS genetics 2007;3(4):e64.
2007: Jane C Goodall; L Ellis; Giles S H Yeo; J S Hill Gaston
Does HLA-B27 influence the monocyte inflammatory response to lipopolysaccharide?
Rheumatology (Oxford, England) 2007;46(2):232-7.
2007: K B L Tan; S H Tan; KH Tan; Giles S H Yeo
Anencephaly in Singapore: a ten-year series 1993-2002.
Singapore medical journal 2007;48(1):12-5.
2006: Juliette Gray; Giles S H Yeo; James Cox; Jenny Morton; Anna-Lynne R Adlam; Julia M Keogh; Jack A Yanovski; Areeg El Gharbawy; Joan C Han; Y C Loraine Tung; John R Hodges; F Lucy Raymond; Stephen O'Rahilly; I Sadaf Farooqi
Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene.
Diabetes 2006;55(12):3366-71.
2006: Shen L Goh; J V K Tan; Kenneth Kwek; Giles S H Yeo
Recurrent non-immune fetal hydrops: A case report.
Annals of the Academy of Medicine, Singapore 2006;35(10):726-8.
2006: Sarah L Gray; Edoardo Dalla Nora; Johannes Grosse; Monia Manieri; Tobias Stoeger; Gema Medina-Gomez; Keith Burling; Sigrid Wattler; Andreas Russ; Giles S H Yeo; V Krishna K Chatterjee; Stephen O'Rahilly; Peter J Voshol; Saverio Cinti; Antonio Vidal-Puig
Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor gamma function (P465L PPARgamma) in mice.
Diabetes 2006;55(10):2669-77.
2006: S L Goh; J V K Tan; Kenneth Kwek; Giles S H Yeo
Recurrent neural tube defects.
Singapore medical journal 2006;47(8):728-9.
2006: Kenneth Kwek; Giles S H Yeo
Shoulder dystocia and injuries: prevention and management.
Current opinion in obstetrics & gynecology 2006;18(2):123-8.
2006: Mark R Pett; M Trent Herdman; Roger D Palmer; Giles S H Yeo; Mahmud K K Shivji; Margaret A Stanley; Nicholas Coleman
Selection of cervical keratinocytes containing integrated HPV16 associates with episome loss and an endogenous antiviral response.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3822-7.
2006: Yung Seng Lee; Benjamin G Challis; Darren A Thompson; Giles S H Yeo; Julia M Keogh; Michael E Madonna; Vicki Wraight; Matthew Sims; Vincent Vatin; David Meyre; Julian Shield; Christine Burren; Zala Ibrahim; Tim Cheetham; Peter Swift; Anthea Blackwood; Chiao-Chien Connie Hung; Nicholas J Wareham; philippe froguel; Glenn L Millhauser; Stephen O'Rahilly; I Sadaf Farooqi
A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance.
Cell metabolism 2006;3(2):135-40.
2006: KH Tan; Kenneth Kwek; Giles S H Yeo
Epidemiology of pre-eclampsia and eclampsia at the KK Women's and Children's Hospital, Singapore.
Singapore medical journal 2006;47(1):48-53.
2005: K B L Tan; T Y T Tan; J V K Tan; Y L Yan; Giles S H Yeo
The amniotic sheet: a truly benign condition?
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2005;26(6):639-43.
2005: KH Tan; T Y T Tan; J Tan; I Tan; S K Chew; Giles S H Yeo
Birth defects in Singapore: 1994-2000.
Singapore medical journal 2005;46(10):545-52.
2005: Kenneth Kwek; Min Li Yeap; KH Tan; John Cs Tee; Giles S H Yeo
Crash caesarean section--decision-to-delivery interval.
Acta obstetricia et gynecologica Scandinavica 2005;84(9):914-5.
2005: Y K Lim; T Y T Tan; R Zuzarte; M L Daniel; Giles S H Yeo
Outcomes of twin-twin transfusion syndrome managed by a specialised twin clinic.
Singapore medical journal 2005;46(8):401-6.
2005: Anthony P Coll; Benjamin G Challis; Miguel López; Sarah Piper; Giles S H Yeo; Stephen O'Rahilly
Proopiomelanocortin-deficient mice are hypersensitive to the adverse metabolic effects of glucocorticoids.
Diabetes 2005;54(8):2269-76.
2005: A T Sia; Kenneth Kwek; Giles S H Yeo
The in vitro effects of clonidine and dexmedetomidine on human myometrium.
International journal of obstetric anesthesia 2005;14(2):104-7.
2005: T Y T Tan; Giles S H Yeo
Intrauterine growth restriction.
Current opinion in obstetrics & gynecology 2005;17(2):135-42.
2005: T L W Lim; KH Tan; CS Tee; Giles S H Yeo
Investigating stillbirths using a simplified obstetric events-based protocol.
Singapore medical journal 2005;46(2):63-8.
2004: J P Wong; W T Seow; Giles S H Yeo
Characteristics of six newborn infants with postnatal findings of severe intracranial haemorrhage.
Annals of the Academy of Medicine, Singapore 2004;33(6):789-92.
2004: Kenneth Kwek; C Khi; H S Ting; Giles S H Yeo
Evaluation of a bedside test for phosphorylated insulin-like growth factor binding protein-1 in preterm labour.
Annals of the Academy of Medicine, Singapore 2004;33(6):780-3.
2004: Giles S H Yeo
Inaugural College of Obstetricians & Gynaecologists Lecture: recent developments in obstetric care and maternal fetal medicine in Singapore.
Annals of the Academy of Medicine, Singapore 2004;33(6):738-42.
2004: Giles S H Yeo; Chiao-Chien Connie Hung; Justin J Rochford; Julia Keogh; Juliette Gray; Shoba Sivaramakrishnan; Stephen O'Rahilly; I Sadaf Farooqi
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay.
Nature neuroscience 2004;7(11):1187-9.
2004: Anthony P Coll; Benjamin G Challis; Giles S H Yeo; Katherine Snell; Sarah J Piper; Halsall David; Rosemary R Thresher; Stephen O'Rahilly
The effects of proopiomelanocortin deficiency on murine adrenal development and responsiveness to adrenocorticotropin.
Endocrinology 2004;145(10):4721-7.
2004: Chiao-Chien Connie Hung; Fraser Pirie; Jian'an Luan; Emma Lank; Ayesha Motala; Giles S H Yeo; Julia M Keogh; Nicholas J Wareham; Stephen O'Rahilly; I Sadaf Farooqi
Studies of the peptide YY and neuropeptide Y2 receptor genes in relation to human obesity and obesity-related traits.
Diabetes 2004;53(9):2461-6.
2004: F M Lai; C C M Ng; Giles S H Yeo
Does maternal serum screening for Down syndrome induce anxiety in younger mothers?
Singapore medical journal 2004;45(8):375-8.
2004: C C M Ng; F M Lai; Giles S H Yeo
Assessment of maternal anxiety levels before and after amniocentesis.
Singapore medical journal 2004;45(8):370-4.
2004: J Kok; KH Tan; S Koh; P S Cheng; W Y Lim; M L Yew; Giles S H Yeo
Antenatal use of a novel vaginal birth training device by term primiparous women in Singapore.
Singapore medical journal 2004;45(7):318-23.
2004: Anthony P Coll; I Sadaf Farooqi; Benjamin G Challis; Giles S H Yeo; Stephen O'Rahilly
Proopiomelanocortin and energy balance: insights from human and murine genetics.
The Journal of clinical endocrinology and metabolism 2004;89(6):2557-62.
2004: Gemma Madsen; Tamas Zakar; Ursula Manuelpillai; Euan Wallace; Kenneth Kwek; Giles S H Yeo; Roger Smith; Sam Mesiano
Intracrine control of estrogen action in human gestational tissues at parturition.
Journal of the Society for Gynecologic Investigation 2004;11(4):213-9.
2004: Stephen O'Rahilly; Giles S H Yeo; I Sadaf Farooqi
Melanocortin receptors weigh in.
Nature medicine 2004;10(4):351-2.
2004: Benjamin G Challis; Anthony P Coll; Giles S H Yeo; Scarlett B Pinnock; Suzanne Dickson; Rosemary R Thresher; Dixon John; Dirk Zahn; Justin J Rochford; A White; R L Oliver; George Millington; Samuel A J R Aparicio; William H Colledge; Andreas Russ; Mark B L Carlton; Stephen O'Rahilly
Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36).
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4695-700.
2003: Giles S H Yeo; Kenneth Siddle
Attractin' more attention - new pieces in the obesity puzzle?
The Biochemical journal 2003;376(Pt 3):e7-8.
2003: J S C Chen; Norman Q Walford; Y L Yan; C L Ong; Giles S H Yeo
Foetal intralobar lung sequestration: antenatal diagnosis and management.
Singapore medical journal 2003;44(12):630-4.
2003: Patricia A Donohoue; Ya-Xiong Tao; Malia Collins; Giles S H Yeo; Stephen O'Rahilly; Deborah L Segaloff
Deletion of codons 88-92 of the melanocortin-4 receptor gene: a novel deleterious mutation in an obese female.
The Journal of clinical endocrinology and metabolism 2003;88(12):5841-5.
2003: Thiam-Chye Tan; T Y T Tan; Kenneth Kwek; John Cs Tee; V S Rajadurai; Giles S H Yeo
Severe newborn encephalopathy unrelated to intrapartum hypoxic events: 3 case reports.
Annals of the Academy of Medicine, Singapore 2003;32(5):653-7.
2003: H H Tan; V C Tan; Giles S H Yeo
A case series of gastrointestinal abnormalities in fetuses with echogenic bowel detected during the antenatal period.
Annals of the Academy of Medicine, Singapore 2003;32(5):649-52.
2003: H Y Wee; T Y T Tan; P C Khoo; P Agarwal; Giles S H Yeo
A case series of pre-viable severe twin-twin transfusion syndrome.
Annals of the Academy of Medicine, Singapore 2003;32(5):645-8.
2003: M S Lau; J V K Tan; T Y T Tan; J M Gomez; Giles S H Yeo
Idiopathic chronic fetomaternal haemorrhage resulting in hydrops--a case report.
Annals of the Academy of Medicine, Singapore 2003;32(5):642-4.
2003: Stephen O'Rahilly; I Sadaf Farooqi; Giles S H Yeo; Benjamin G Challis
Minireview: human obesity-lessons from monogenic disorders.
Endocrinology 2003;144(9):3757-64.
2003: Norman Q Walford; Kyaw Htun; Jeanette Chen; Yan Ying Liu; Harvey Teo; Giles S H Yeo
Intralobar sequestration of the lung is a congenital anomaly: anatomopathological analysis of four cases diagnosed in fetal life.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2003;6(4):314-21.
2003: Chiao-Chien Connie Hung; I Sadaf Farooqi; Ken Ong; Jian'an Luan; Julia M Keogh; Marcus E Pembrey; Giles S H Yeo; David D Dunger; Nicholas J Wareham; Stephen O' Rahilly
Contribution of variants in the small heterodimer partner gene to birthweight, adiposity, and insulin levels: mutational analysis and association studies in multiple populations.
Diabetes 2003;52(5):1288-91.
2003: I Sadaf Farooqi; Julia M Keogh; Giles S H Yeo; Emma Lank; Tim Cheetham; Stephen O'Rahilly
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene.
The New England journal of medicine 2003;348(12):1085-95.
2003: Giles S H Yeo; Emma Lank; I Sadaf Farooqi; Julia Keogh; Benjamin G Challis; Stephen O'Rahilly
Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms.
Human molecular genetics 2003;12(5):561-74.
2003: C Y Chen; Kenneth Kwek; KH Tan; Giles S H Yeo
Our experience with eclampsia in Singapore.
Singapore medical journal 2003;44(2):88-93.
2002: Benjamin G Challis; Giles S H Yeo
Past, present and future strategies to study the genetics of body weight regulation.
Briefings in functional genomics & proteomics 2002;1(3):290-304.
2002: Benjamin G Challis; Lynn E Pritchard; John W M Creemers; Jerome Delplanque; Julia M Keogh; Jian'an Luan; Nicholas J Wareham; Giles S H Yeo; Sumit Bhattacharyya; philippe froguel; Anne White; I Sadaf Farooqi; Stephen O'Rahilly
A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism.
Human molecular genetics 2002;11(17):1997-2004.
2002: Jackie Y l Tan; Keh Chuan Loh; Giles S H Yeo; Yam Cheng Chee
Transient hyperthyroidism of hyperemesis gravidarum.
BJOG : an international journal of obstetrics and gynaecology 2002;109(6):683-8.
2002: Kenneth Kwek; Giles S H Yeo
Current understanding of pre-eclampsia.
Annals of the Academy of Medicine, Singapore 2002;31(3):320-7.
2002: Vivion E F Crowley; Giles S H Yeo; Stephen O'Rahilly
Obesity therapy: altering the energy intake-and-expenditure balance sheet.
Nature reviews. Drug discovery 2002;1(4):276-86.
2002: F M Lai; B H Woo; KH Tan; J Huang; S T Lee; T B Yan; B H Tan; S K Chew; Giles S H Yeo
Birth prevalence of Down syndrome in Singapore from 1993 to 1998.
Singapore medical journal 2002;43(2):070-6.
2001: J P Wong; Kenneth Kwek; Jackie Y l Tan; Giles S H Yeo
Fetal congenital complete heart block: prophylaxis with intravenous gammaglobulin and treatment with dexamethasone.
The Australian & New Zealand journal of obstetrics & gynaecology 2001;41(3):339-41.
2000: I Sadaf Farooqi; Giles S H Yeo; Julia M Keogh; S Aminian; Susan A Jebb; G Butler; Tim Cheetham; Stephen O'Rahilly
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency.
The Journal of clinical investigation 2000;106(2):271-9.
2000: Benjamin G Challis; Giles S H Yeo; I Sadaf Farooqi; Jian'an Luan; S Aminian; Halsall David; Julia M Keogh; Nicholas J Wareham; Stephen O'Rahilly
The CART gene and human obesity: mutational analysis and population genetics.
Diabetes 2000;49(5):872-5.
2000: A Wong; KH Tan; CS Tee; Giles S H Yeo
Seroprevalence of cytomegalovirus, toxoplasma and parvovirus in pregnancy.
Singapore medical journal 2000;41(4):151-5.
2000: Giles S H Yeo; I Sadaf Farooqi; Benjamin G Challis; Robert S Jackson; Stephen O'Rahilly
The role of melanocortin signalling in the control of body weight: evidence from human and murine genetic models.
QJM : monthly journal of the Association of Physicians 2000;93(1):7-14.
1999: C C Chan; I Malathi; Giles S H Yeo
Is the vacuum extractor really the instrument of first choice?
The Australian & New Zealand journal of obstetrics & gynaecology 1999;39(3):305-9.
1999: W L Tham; KH Tan; CS Tee; Giles S H Yeo
Confidential enquiry of stillbirths in current obstetric practice.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 1999;64(3):287-96.
1998: Giles S H Yeo; I Sadaf Farooqi; S Aminian; Halsall David; R G Stanhope; Stephen O'Rahilly
A frameshift mutation in MC4R associated with dominantly inherited human obesity.
Nature genetics 1998;20(2):111-2.
1998: Kenneth Kwek; Y G Chan; KH Tan; Giles S H Yeo
Validation of an oscillometric electronic sphygmomanometer in an obstetric population.
American journal of hypertension 1998;11(8 Pt 1):978-82.
1998: S F Loh; A Woodworth; Giles S H Yeo
Umbilical cord blood gas analysis at delivery.
Singapore medical journal 1998;39(4):151-5.
1998: F M Lai; Giles S H Yeo
Down syndrome screening in Singapore--the effectiveness of a second trimester serum screening policy modelled on 29,360 pregnancies in KK Women's and Children's Hospital.
Singapore medical journal 1998;39(2):69-75.
1997: T C Chang; T S Chew; M Pang; A C Tan; Giles S H Yeo
Cervicovaginal foetal fibronectin in the prediction of preterm labour in a low-risk population.
Annals of the Academy of Medicine, Singapore 1997;26(6):776-80.
1997: T C Chang; K T Tan; P Neow; Giles S H Yeo
Computerised analysis of foetal heart rate variation: prediction of adverse perinatal outcome in patients undergoing prostaglandin induction of labour at term.
Annals of the Academy of Medicine, Singapore 1997;26(6):772-5.
1997: CT Yeong; KH Tan; CS Tee; Giles S H Yeo
Optimising management of stillbirths in modern Singapore.
Singapore medical journal 1997;38(8):317-20.
1997: L H Chen; CT Yeong; Giles S H Yeo
Three cases of fatal pulmonary embolism in obstetrics.
Annals of the Academy of Medicine, Singapore 1997;26(3):356-9.
1996: B H Chow; S F Loh; Y L Yan; H K Ang; Giles S H Yeo
Holoprosencephaly and chromosomal anomalies.
Singapore medical journal 1996;37(4):394-7.
1996: Y Y Tan; Giles S H Yeo
Impaired glucose tolerance in pregnancy--is it of consequence?
The Australian & New Zealand journal of obstetrics & gynaecology 1996;36(3):248-55.
1995: Giles S H Yeo; KH Tan; T C Liu
The role of discriminant functions in screening for beta-thalassaemia traits during pregnancy.
Singapore medical journal 1995;36(6):615-8.
1995: Giles S H Yeo; Y W Lim; CT Yeong; T C Tan
An analysis of risk factors for the prediction of shoulder dystocia in 16,471 consecutive births.
Annals of the Academy of Medicine, Singapore 1995;24(6):836-40.
1995: L H Chen; KH Tan; Giles S H Yeo
A ten-year review of uterine rupture in modern obstetric practice.
Annals of the Academy of Medicine, Singapore 1995;24(6):830-5.
1995: Y Y Tan; P C Liauw; Giles S H Yeo
Using glucose tolerance test results to predict insulin requirement in women with gestational diabetes.
The Australian & New Zealand journal of obstetrics & gynaecology 1995;35(3):262-6.
1995: Y L Yan; Y Y Tan; T C Chang; Giles S H Yeo
Second trimester colour Doppler imaging of the uterine artery: reproducibility of the resistance index.
The Australian & New Zealand journal of obstetrics & gynaecology 1995;35(3):254-6.
1994: S A Tan; H H Cheng; Giles S H Yeo
Birth defects--the state of awareness amongst mothers.
Singapore medical journal 1994;35(5):471-4.
1994: Giles S H Yeo; W B Chan; K C Lun; F M Lai
Racial differences in fetal morphometry in Singapore.
Annals of the Academy of Medicine, Singapore 1994;23(3):371-6.
1994: Giles S H Yeo; KH Tan; T C Liu
Screening for beta thalassaemia and HbE traits with the mean red cell volume in pregnant women.
Annals of the Academy of Medicine, Singapore 1994;23(3):363-6.
1994: S A Tan; Giles S H Yeo; H H Cheng
Birth defects--the state of awareness.
Singapore medical journal 1994;35(1):67-70.
1992: Giles S H Yeo; A A Ali
The effect of prenatal diagnosis on the incidence of Down syndrome livebirths in the Singapore General Hospital.
Singapore medical journal 1992;33(1):38-41.
1991: W B Chan; Giles S H Yeo
A comparison of fetal biparietal diameter measurements between local Chinese and Caucasian populations.
Singapore medical journal 1991;32(4):214-7.