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Lilián Yépez-Mulia

Research Profile

Chemicals & Drugs

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Inhibitory Concentration 50

Disorders

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Parasitic Sensitivity Tests

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Mexico

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Drug Design

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Publications

TOP 3
Félix Matadamas-Martínez; Guillermo Mendoza; Benjamín Nogueda-Torres; Javier R Ambrosio; Gabriela Andrés-Antonio; Rafael Castillo; Alicia Hernández-Campos; Francisco Hernández-Luis; Lilián Yépez-Mulia
Analysis of the effect of a 2-(trifluoromethyl)-1H-benzimidazole derivative on Trichinella spiralis muscle larvae.
Rodrigo Aguayo-Ortiz; Rafael Castillo; Francisco Hernández-Luis; Jose Medina-Franco; Oscar Méndez-Lucio; Lilián Yépez-Mulia; Alicia Hernández-Campos
Towards the identification of the binding site of benzimidazoles to β-tubulin of Trichinella spiralis: insights from computational and experimental data.
Carlos Hernández-Covarrubias; Rafael Castillo; Alicia Hernández-Campos; Gabriel Navarrete-Vázquez; Remedios Sánchez-Díaz; Miguel A Vilchis-Reyes; Lilián Yépez-Mulia; Francisco Hernández-Luis
Exploring the interplay of physicochemical properties, membrane permeability and giardicidal activity of some benzimidazole derivatives.

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All Publications

2013: Félix Matadamas-Martínez; Guillermo Mendoza; Benjamín Nogueda-Torres; Javier R Ambrosio; Gabriela Andrés-Antonio; Rafael Castillo; Alicia Hernández-Campos; Francisco Hernández-Luis; Lilián Yépez-Mulia
Analysis of the effect of a 2-(trifluoromethyl)-1H-benzimidazole derivative on Trichinella spiralis muscle larvae.
Veterinary parasitology 2013;194(2-4):193-7.
2013: Rodrigo Aguayo-Ortiz; Rafael Castillo; Francisco Hernández-Luis; Jose Medina-Franco; Oscar Méndez-Lucio; Lilián Yépez-Mulia; Alicia Hernández-Campos
Towards the identification of the binding site of benzimidazoles to β-tubulin of Trichinella spiralis: insights from computational and experimental data.
Journal of molecular graphics & modelling 2013;41():12-9.
2012: Carlos Hernández-Covarrubias; Rafael Castillo; Alicia Hernández-Campos; Gabriel Navarrete-Vázquez; Remedios Sánchez-Díaz; Miguel A Vilchis-Reyes; Lilián Yépez-Mulia; Francisco Hernández-Luis
Exploring the interplay of physicochemical properties, membrane permeability and giardicidal activity of some benzimidazole derivatives.
European journal of medicinal chemistry 2012;52():193-204.
2012: Dylan L Díaz-Chiguer; Alicia Hernández-Campos; Javier Ambrosio; Rafael Castillo; Gloria de la Luz León-Ávila; Adrián Márquez-Navarro; Rocío Nieto-Meneses; Benjamín Nogueda-Torres; Jaime Pérez-Villanueva; Lilián Yépez-Mulia; Francisco Hernández-Luis
In vitro and in vivo trypanocidal activity of some benzimidazole derivatives against two strains of Trypanosoma cruzi.
Acta tropica 2012;122(1):108-12.
2012: Adelina Jiménez-Arellanes; Rosalba León-Díaz; Julieta Luna-Herrera; Mariana Meckes; Gloria María Molina-Salinas; Amparo Tapia; Lilián Yépez-Mulia
Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes.
Evidence-based complementary and alternative medicine : eCAM 2012;2012():593403.
2011: Jaime Pérez-Villanueva; Antonio Romo-Mancillas; Lilián Yépez-Mulia; Alicia Hernández-Campos; Francisco Hernández-Luis; Rafael Castillo
Antiprotozoal activity of proton-pump inhibitors.
Bioorganic & medicinal chemistry letters 2011;21(24):7351-4.
2011: E N Pompa-Mera; Lilián Yépez-Mulia; E A García-Zepeda; A Ocaña-Mondragón; Guadalupe Ortega-Pierres; César González-Bonilla
Trichinella spiralis: intranasal immunization with attenuated Salmonella enterica carrying a gp43 antigen-derived 30mer epitope elicits protection in BALB/c mice.
Experimental parasitology 2011;129(4):393-401.
2011: Fabian López-Vallejo; Rafael Castillo; Lilián Yépez-Mulia; José L Medina-Franco
Benzotriazoles and indazoles are scaffolds with biological activity against Entamoeba histolytica.
Journal of biomolecular screening 2011;16(8):862-8.
2011: Antonio Romo-Mancillas; Alfredo Téllez-Valencia; Lilián Yépez-Mulia; Alicia Hernández-Campos; Francisco Hernández-Luis; Rafael Castillo
The design and inhibitory profile of new benzimidazole derivatives against triosephosphate isomerase from Trypanosoma cruzi: a problem of residue motility.
Journal of molecular graphics & modelling 2011;30():90-9.
2011: Jaime Pérez-Villanueva; Lilián Yépez-Mulia; Thomas R Caulfield; Alicia Hernández-Campos; Francisco Hernández-Luis; José L Medina-Franco; Rafael Castillo
Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) of some benzimidazole derivatives with trichomonicidal activity.
European journal of medicinal chemistry 2011;46(8):3499-508.
2011: Yareli Rojas-Aguirre; Lilián Yépez-Mulia; Ivan Castillo; Fabian López-Vallejo; Olivia Soria-Arteche; Alicia Hernández-Campos; Rafael Castillo; Francisco Hernández-Luis
Studies on 6-chloro-5-(1-naphthyloxy)-2-(trifluoromethyl)-1H-benzimidazole/2-hydroxypropyl-β-cyclodextrin association: Characterization, molecular modeling studies, and in vivo anthelminthic activity.
Bioorganic & medicinal chemistry 2011;19(2):789-97.
2010: Samira Muñoz-Cruz; Argelia Gómez-García; Jarenny Millán-Ibarra; Silvia Giono Cerezo; Lilián Yépez-Mulia
Giardia lamblia: interleukin 6 and tumor necrosis factor-alpha release from mast cells induced through an Ig-independent pathway.
Experimental parasitology 2010;126(3):298-303.
2010: Francisco Hernández-Luis; Alicia Hernández-Campos; Rafael Castillo; Gabriel Navarrete-Vázquez; Olivia Soria-Arteche; Manuel Hernández-Hernández; Lilián Yépez-Mulia
Synthesis and biological activity of 2-(trifluoromethyl)-1H-benzimidazole derivatives against some protozoa and Trichinella spiralis.
European journal of medicinal chemistry 2010;45(7):3135-41.
2009: Adrián Márquez-Navarro; Benjamín Nogueda-Torres; Alicia Hernández-Campos; Olivia Soria-Arteche; Rafael Castillo; Sergio Rodríguez-Morales; Lilián Yépez-Mulia; Francisco Hernández-Luis
Anthelmintic activity of benzimidazole derivatives against Toxocara canis second-stage larvae and Hymenolepis nana adults.
Acta tropica 2009;109(3):232-5.
2009: David Valdez-Padilla; Sergio Rodríguez-Morales; Alicia Hernández-Campos; Francisco Hernández-Luis; Lilián Yépez-Mulia; Amparo Tapia-Contreras; Rafael Castillo
Synthesis and antiprotozoal activity of novel 1-methylbenzimidazole derivatives.
Bioorganic & medicinal chemistry 2009;17(4):1724-30.
2009: Roberto Cedillo-Rivera; Yelda A Leal; Lilián Yépez-Mulia; Alejandro Gómez-Delgado; Guadalupe Ortega-Pierres; Roberto Tapia-Conyer; Onofre Muñoz
Seroepidemiology of giardiasis in Mexico.
The American journal of tropical medicine and hygiene 2009;80(1):6-10.
2007: Lilián Yépez-Mulia; R Hernández-Bello; N Arizmendi-Puga; Rocío Fonseca-Liñán; Guadalupe Ortega-Pierres
Contributions to the study of Trichinella spiralis TSL-1 antigens in host immunity.
Parasite immunology 2007;29(12):661-70.
2007: Julio C Rivera; Lilián Yépez-Mulia; Alicia Hernández-Campos; Rafael Moreno-Esparza; Rafael Castillo; Gabriel Navarrete-Vázquez; Inés Fuentes-Noriega; Helgi Jung-Cook
Biopharmaceutic evaluation of novel anthelmintic (1H-benzimidazol-5(6)-yl)carboxamide derivatives.
International journal of pharmaceutics 2007;343(1-2):159-65.
2007: Fernando Calzada; Lilián Yépez-Mulia; Amparo Tapia-Contreras
Effect of Mexican medicinal plant used to treat trichomoniasis on Trichomonas vaginalis trophozoites.
Journal of ethnopharmacology 2007;113(2):248-51.
2006: Fernando Calzada; Lilián Yépez-Mulia; Abigaíl Aguilar
In vitro susceptibility of Entamoeba histolytica and Giardia lamblia to plants used in Mexican traditional medicine for the treatment of gastrointestinal disorders.
Journal of ethnopharmacology 2006;108(3):367-70.
2006: Narcy G Arizmendi-Puga; Jose Antonio Enciso; Guadalupe Ortega-Pierres; Zhongwei Zhao; Marek Duszyk; Marina Ulanova; A Dean Befus; Lilián Yépez-Mulia
Trichinella spiralis: histamine secretion induced by TSL-1 antigens from unsensitized mast cells.
Experimental parasitology 2006;114(2):67-76.
2006: Guadalupe Beatriz Rodríguez-Fuentes; Roberto Cedillo-Rivera; Rocío Fonseca-Liñán; Raúl Argüello-García; Onofre Muñoz; Guadalupe Ortega-Pierres; Lilián Yépez-Mulia
Giardia duodenalis: analysis of secreted proteases upon trophozoite-epithelial cell interaction in vitro.
Memórias do Instituto Oswaldo Cruz 2006;101(6):693-6.
2006: Gabriel Navarrete-Vázquez; María de Monserrat Rojano-Vilchis; Lilián Yépez-Mulia; Víctor Meléndez; Lucia Gerena; Alicia Hernández-Campos; Rafael Castillo; Francisco Hernández-Luis
Synthesis and antiprotozoal activity of some 2-(trifluoromethyl)-1H-benzimidazole bioisosteres.
European journal of medicinal chemistry 2006;41(1):135-41.
2005: Fernando Calzada; J Antonio Cervantes-Martínez; Lilián Yépez-Mulia
In vitro antiprotozoal activity from the roots of Geranium mexicanum and its constituents on Entamoeba histolytica and Giardia lamblia.
Journal of ethnopharmacology 2005;98(1-2):191-3.
2004: Violeta Niborski; Isabelle Vallée; Rocío Fonseca-Liñán; Pascal BOIREAU; Antonio Enciso; Guadalupe Ortega-Pierres; Lilián Yépez-Mulia
Trichinella spiralis: stimulation of mast cells by TSL-1 antigens trigger cytokine mRNA expression and release of IL-4 and TNF through an Ig-independent pathway.
Experimental parasitology 2004;108(3-4):101-8.
2004: Gabriel López-Velázquez; Dora Molina-Ortiz; Nallely Cabrera; Gloria Hernández-Alcántara; Jorge Peon-Peralta; Lilián Yépez-Mulia; Ruy Pérez-Montfort; Horacio Reyes-Vivas
An unusual triosephosphate isomerase from the early divergent eukaryote Giardia lamblia.
Proteins 2004;55(4):824-34.
2002: Mariola Andrzejewska; Lilián Yépez-Mulia; Roberto Cedillo-Rivera; Amparo Tapia; Leena Vilpo; Juhani Vilpo; Zygmunt Kazimierczuk
Synthesis, antiprotozoal and anticancer activity of substituted 2-trifluoromethyl- and 2-pentafluoroethylbenzimidazoles.
European journal of medicinal chemistry 2002;37(12):973-8.
2002: Roberto Cedillo-Rivera; Bibiana Chávez; Arturo González-Robles; Amparo Tapia; Lilián Yépez-Mulia
In vitro effect of nitazoxanide against Entamoeba histolytica, Giardia intestinalis and Trichomonas vaginalis trophozoites.
The Journal of eukaryotic microbiology 2002;49(3):201-8.
2001: Francisco Hernández-Luis; Alicia Hernández-Campos; Lilián Yépez-Mulia; Roberto Cedillo; Rafael Castillo
Synthesis and hydrolytic stability studies of albendazole carrier prodrugs.
Bioorganic & medicinal chemistry letters 2001;11(11):1359-62.
2001: N Arizmendi; Lilián Yépez-Mulia; Roberto Cedillo-Rivera; Guadalupe Ortega-Pierres; Onofre Muñoz; D Befus; J Antonio Enciso-Moreno
Interleukin mRNA changes in mast cells stimulated by TSL-1 antigens.
Parasite (Paris, France) 2001;8(2 Suppl):S114-6.
2000: Guadalupe Ortega-Pierres; C Arriaga; Lilián Yépez-Mulia
Epidemiology of trichinellosis in Mexico, Central and South America.
Veterinary parasitology 2000;93(3-4):201-25.
1999: Lilián Yépez-Mulia; R Morales-Hurtado; N Viveros-Guzmán; Roberto Cedillo-Rivera; Francisco Hernández-Luis; Rafael Castillo; Alicia Hernández-Campos; Onofre Muñoz
Evaluation of albendazole prodrugs in experimental trichinellosis.
Archives of medical research 1999;30(5):368-74.