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H Yokokura

Research Profile

Chemicals & Drugs

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Publications

TOP 3
H Yokokura; M Osawa; T Inoue; I Umezawa; Y Naito; M Ikura; H Hidaka
Symmetric covalent linkage of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) results in novel derivatives with increased inhibitory activities against calcium/calmodulin complex.
Yoshitaka Hayashi; Masashi Nishio; Y Naito; H Yokokura; Yuji Nimura; H Hidaka; Yasuo Watanabe
Regulation of neuronal nitric-oxide synthase by calmodulin kinases.
H Sakaguchi; H Yokokura; O Terada; Y Naito; Yuji Nimura; H Hidaka
Unique inhibitory action of the synthetic compound 2-[N-(2-aminoethyl)-N-(5-isoquinolinesulfonyl)] amino-N-(4-chlorocinnamyl)-N-methylbenzylamine (CKA-1306) against calcium/calmodulin-dependent protein kinase I.

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All Publications

1999: H Yokokura; M Osawa; T Inoue; I Umezawa; Y Naito; M Ikura; H Hidaka
Symmetric covalent linkage of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) results in novel derivatives with increased inhibitory activities against calcium/calmodulin complex.
Drug design and discovery 1999;16(3):203-16.
1999: Yoshitaka Hayashi; Masashi Nishio; Y Naito; H Yokokura; Yuji Nimura; H Hidaka; Yasuo Watanabe
Regulation of neuronal nitric-oxide synthase by calmodulin kinases.
The Journal of biological chemistry 1999;274(29):20597-602.
1998: H Sakaguchi; H Yokokura; O Terada; Y Naito; Yuji Nimura; H Hidaka
Unique inhibitory action of the synthetic compound 2-[N-(2-aminoethyl)-N-(5-isoquinolinesulfonyl)] amino-N-(4-chlorocinnamyl)-N-methylbenzylamine (CKA-1306) against calcium/calmodulin-dependent protein kinase I.
Biochemical pharmacology 1998;56(3):329-34.
1997: Y Naito; Yasuo Watanabe; H Yokokura; Ryotaro Sugita; Masashi Nishio; H Hidaka
Isoform-specific activation and structural diversity of calmodulin kinase I.
The Journal of biological chemistry 1997;272(51):32704-8.
1997: H Yokokura; O Terada; Y Naito; H Hidaka
Isolation and comparison of rat cDNAs encoding Ca2+/calmodulin-dependent protein kinase I isoforms.
Biochimica et biophysica acta 1997;1338(1):8-12.
1997: H Yokokura; O Terada; Y Naito; Ryotaro Sugita; H Hidaka
Cascade activation of the calmodulin kinase family.
Advances in second messenger and phosphoprotein research 1997;31():151-7.
1996: Ichiro Niki; H Yokokura; T Sudo; Masashi Kato; H Hidaka
Ca2+ signaling and intracellular Ca2+ binding proteins.
Journal of biochemistry 1996;120(4):685-98.
1996: H Yokokura; Y Okada; O Terada; H Hidaka
HMN-709, a chlorobenzenesulfonamide derivative, is a new membrane-permeable calmodulin antagonist.
Japanese journal of pharmacology 1996;72(2):127-35.
1996: N H Win; T Ishikawa; N Saito; Masashi Kato; H Yokokura; Yasuo Watanabe; Y Iida; H Hidaka
A new and potent calmodulin antagonist, HF-2035, which inhibits vascular relaxation induced by nitric oxide synthase.
European journal of pharmacology 1996;299(1-3):119-26.
1996: H Hidaka; H Yokokura
Molecular and cellular pharmacology of a calcium/calmodulin-dependent protein kinase II (CaM kinase II) inhibitor, KN-62, and proposal of CaM kinase phosphorylation cascades.
Advances in pharmacology (San Diego, Calif.) 1996;36():193-219.
1995: H Yokokura; Marina R Picciotto; Angus Nairn; H Hidaka
The regulatory region of calcium/calmodulin-dependent protein kinase I contains closely associated autoinhibitory and calmodulin-binding domains.
The Journal of biological chemistry 1995;270(40):23851-9.
1994: R Sugita; H Mochizuki; Tomomi Ito; H Yokokura; R Kobayashi; H Hidaka
Ca2+/calmodulin-dependent protein kinase kinase cascade.
Biochemical and biophysical research communications 1994;203(1):694-701.
1994: Tomomi Ito; H Yokokura; Angus Nairn; Yuji Nimura; H Hidaka
Ca2+/calmodulin-dependent protein kinase V and I may form a family of isoforms.
Biochemical and biophysical research communications 1994;201(3):1561-6.