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T Yokota

Research Profile

Chemicals & Drugs

Disorders

Hypersensitivity

Living Beings

Mouse
Rats

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Physiology

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Basophils

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Amino Acid Sequences

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Publications

TOP 3
T Takai; H Hatanaka; S Ichikawa; T Yokota; Fuyuhiko Inagaki; Y Okumura
Effects of double mutation at two distant IgE-binding sites in the three-dimensional structure of the major house dust mite allergen Der f 2 on IgE-binding and histamine-releasing activity.
T Takai; K Takahashi; M Akagawa-Chihara; M Fukada; T Yuuki; I Shibuya; K Okumura; C Ra; T Yokota; Y Okumura
Production of humanized antibody against human high-affinity IgE receptor in a serum-free culture of CHO cells, and purification of the Fab fragments.
K Takahashi; T Takai; T Yasuhara; T Yokota; Y Okumura
Effects of site-directed mutagenesis in the cysteine residues and the N-glycosylation motif in recombinant Der f 1 on secretion and protease activity.

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All Publications

2001: T Takai; H Hatanaka; S Ichikawa; T Yokota; Fuyuhiko Inagaki; Y Okumura
Effects of double mutation at two distant IgE-binding sites in the three-dimensional structure of the major house dust mite allergen Der f 2 on IgE-binding and histamine-releasing activity.
Bioscience, biotechnology, and biochemistry 2001;65(7):1601-9.
2001: T Takai; K Takahashi; M Akagawa-Chihara; M Fukada; T Yuuki; I Shibuya; K Okumura; C Ra; T Yokota; Y Okumura
Production of humanized antibody against human high-affinity IgE receptor in a serum-free culture of CHO cells, and purification of the Fab fragments.
Bioscience, biotechnology, and biochemistry 2001;65(5):1082-9.
2001: K Takahashi; T Takai; T Yasuhara; T Yokota; Y Okumura
Effects of site-directed mutagenesis in the cysteine residues and the N-glycosylation motif in recombinant Der f 1 on secretion and protease activity.
International archives of allergy and immunology 2001;124(4):454-60.
2001: T Takai; M Akagawa-Chihara; T Yokota; Y Okumura
Reactivities of mutants of a major house dust mite allergen Der f 2 to mouse anti-Der f 2 monoclonal antibodies analyzed by immunoblotting.
Bioscience, biotechnology, and biochemistry 2001;65(3):694-7.
2001: K Takahashi; C Nishiyama; K Okumura; C Ra; Y Ohtake; T Yokota
Molecular cloning of rat USF2 cDNA and characterization of splicing variants.
Bioscience, biotechnology, and biochemistry 2001;65(1):56-62.
2001: T Takai; K Okumura; C Ra; T Yokota; Y Okumura
Expression of humanized Fab fragments that recognize the IgE-binding domain of human Fc(epsilon)RIalpha in COS and CHO cells.
Journal of biochemistry 2001;129(1):5-12.
2000: T Takai; S Ichikawa; T Yokota; H Hatanaka; Fuyuhiko Inagaki; Y Okumura
Unlocking the allergenic structure of the major house dust mite allergen der f 2 by elimination of key intramolecular interactions.
FEBS letters 2000;484(2):102-7.
2000: K Takahashi; T Takai; T Yasuhara; T Yuuki; Y Ohtake; T Yokota; Y Okumura
Production of enzymatically and immunologically active Der f 1 in Escherichia coli.
International archives of allergy and immunology 2000;122(2):108-14.
1999: C Nishiyama; T Yokota; K Okumura; C Ra
The transcription factors Elf-1 and GATA-1 bind to cell-specific enhancer elements of human high-affinity IgE receptor alpha-chain gene.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(2):623-30.
1999: M Yasue; T Yokota; H Okudaira; Y Okumura
Induction of allergic reactions in guinea pigs with purified house dust mite allergens.
Cellular immunology 1999;192(2):185-93.
1999: C Nishiyama; H Hatanaka; S Ichikawa; M Fukada; M Akagawa-Chihara; T Yuuki; T Yokota; Fuyuhiko Inagaki; Y Okumura
Analysis of human IgE epitope of Der f 2 with anti-Der f 2 mouse monoclonal antibodies.
Molecular immunology 1999;36(1):53-60.
1998: M Yasue; T Yokota; Matsunobu Suko; H Okudaira; Y Okumura
Comparison of sensitization to crude and purified house dust mite allergens in inbred mice.
Laboratory animal science 1998;48(4):346-52.
1998: M Yasue; T Yokota; M Fukada; T Takai; Matsunobu Suko; H Okudaira; Y Okumura
Hyposensitization to allergic reaction in rDer f 2-sensitized mice by the intranasal administration of a mutant of rDer f 2, C8/119S.
Clinical and experimental immunology 1998;113(1):1-9.
1998: M Yasue; S Nakamura; T Yokota; H Okudaira; Y Okumura
Experimental monkey model sensitized with mite antigen.
International archives of allergy and immunology 1998;115(4):303-11.
1998: M Yasue; T Yokota; M Yuasa; Y Kajiwara; Matsunobu Suko; H Okudaira
Effects of oral hyposensitization with recombinant Der f2 on immediate airway constriction in a murine allergic model.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;11(1):144-50.
1997: M Yasue; T Yokota; Y Kajiwara; Matsunobu Suko; H Okudaira
Inhibition of airway inflammation in rDer f 2-sensitized mice by oral administration of recombinant der f 2.
Cellular immunology 1997;181(1):30-7.
1997: T Takai; T Yokota; M Yasue; C Nishiyama; T Yuuki; A Mori; H Okudaira; Y Okumura
Engineering of the major house dust mite allergen Der f 2 for allergen-specific immunotherapy.
Nature biotechnology 1997;15(8):754-8.