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Mark Yore

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Tumor Cell Line

Physiology

Phenomena

Phosphorylation

Disorders

Lung Neoplasms

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Publications

TOP 3
Julie Norseen; David A Phillips; Ulf Smith; Anny Usheva; Mark M Yore; Pratik Aryal; Roger J Davis; Ann Hammarstedt; Tetsuya Hosooka; Shashi Kant; Urban A Kiernan; Bettina J Kraus; Hiroshi Maruyama; Barbara B Kahn
Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinol-independent mechanism.
Michael B Sporn; Karen T Liby; Mark M Yore; Liangfeng Fu; Justin M Lopchuk; Gordon W Gribble
New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress.
Mark M Yore; Michael B Sporn; Scott A Gerber; Arminja N Kettenbach; Karen T Liby
Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR.

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All Publications

2012: Julie Norseen; David A Phillips; Ulf Smith; Anny Usheva; Mark M Yore; Pratik Aryal; Roger J Davis; Ann Hammarstedt; Tetsuya Hosooka; Shashi Kant; Urban A Kiernan; Bettina J Kraus; Hiroshi Maruyama; Barbara B Kahn
Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinol-independent mechanism.
Molecular and cellular biology 2012;32(10):2010-9.
2011: Michael B Sporn; Karen T Liby; Mark M Yore; Liangfeng Fu; Justin M Lopchuk; Gordon W Gribble
New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress.
Journal of natural products 2011;74(3):537-45.
2011: Mark M Yore; Michael B Sporn; Scott A Gerber; Arminja N Kettenbach; Karen T Liby
Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR.
PloS one 2011;6(7):e22862.
2009: Karen Liby; Renee Risingsong; Darlene B Royce; Charlotte R Williams; Tian Ma; Mark M Yore; Michael B Sporn
Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice.
Cancer prevention research (Philadelphia, Pa.) 2009;2(12):1050-8.
2008: Karen Liby; Mark M Yore; Bill D Roebuck; Karen J Baumgartner; Tadashi Honda; Chitra Sundararajan; Hidenori Yoshizawa; Gordon W Gribble; Charlotte R Williams; Renee Risingsong; Darlene B Royce; Albena T Dinkova-Kostova; Katherine K Stephenson; Patricia A Egner; Melinda S Yates; John Groopman; Thomas W Kensler; Michael B. Sporn
A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.
Cancer research 2008;68(16):6727-33.
2008: Karen Liby; Renee Risingsong; Darlene B Royce; Charlotte R Williams; Mark M Yore; Tadashi Honda; Gordon W Gribble; William W Lamph; Nicola Vannini; Ilaria Sogno; Adriana Albini; Michael B. Sporn
Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl Ester and the rexinoid LG100268.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(14):4556-63.
2008: Karen T Liby; Candice C Black; Darlene B Royce; Charlotte R Williams; Renee Risingsong; Mark M Yore; Xi Liu; Tadashi Honda; Gordon W Gribble; William W Lamph; Thomas A Sporn; Ethan Dmitrovsky; Michael B. Sporn
The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis.
Molecular cancer therapeutics 2008;7(5):1251-7.
2007: Karen T Liby; Mark M Yore; Michael B. Sporn
Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.
Nature reviews. Cancer 2007;7(5):357-69.
2007: Karen T Liby; Darlene B Royce; Charlotte R Williams; Renee Risingsong; Mark M Yore; Tadashi Honda; Gordon W Gribble; Ethan Dmitrovsky; Thomas A Sporn; Michael B. Sporn
The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice.
Cancer research 2007;67(6):2414-9.
2006: Mark M Yore; Karen T Liby; Tadashi Honda; Gordon W Gribble; Michael B. Sporn
The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta.
Molecular cancer therapeutics 2006;5(12):3232-9.
2006: Stacey K Ogden; David J Casso; Manuel Ascano; Mark M Yore; Thomas B Kornberg; David J. Robbins
Smoothened regulates activator and repressor functions of Hedgehog signaling via two distinct mechanisms.
The Journal of biological chemistry 2006;281(11):7237-43.
2006: Melinda S Yates; Mi-Kyoung Kwak; Patricia A Egner; John Groopman; Sridevi Bodreddigari; Thomas R Sutter; Karen J Baumgartner; Bill D Roebuck; Karen T Liby; Mark M Yore; Tadashi Honda; Gordon W Gribble; Michael B. Sporn; Thomas W Kensler
Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.
Cancer research 2006;66(4):2488-94.
2005: Karen T Liby; Thomas Hock; Mark M Yore; Nanjoo Suh; Andrew E Place; Renee Risingsong; Charlotte R Williams; Darlene B Royce; Tadashi Honda; Yukiko Honda; Gordon W Gribble; Nathalie Hill-Kapturczak; Anupam Agarwal; Michael B. Sporn
The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling.
Cancer research 2005;65(11):4789-98.
2005: Kristina A White; Mark M Yore; Dexin Deng; Michael J Spinella
Limiting effects of RIP140 in estrogen signaling: potential mediation of anti-estrogenic effects of retinoic acid.
The Journal of biological chemistry 2005;280(9):7829-35.
2003: Kristina A White; Mark M Yore; Shannon L Warburton; Angelina V Vaseva; Erica Rieder; Sarah J Freemantle; Michael J Spinella
Negative feedback at the level of nuclear receptor coregulation. Self-limitation of retinoid signaling by RIP140.
The Journal of biological chemistry 2003;278(45):43889-92.