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Hiromi Yoshida
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70
Mizushina, Yoshiyuki
49
Sakaguchi, Kengo
45
Sugawara, Fumio
26
Kuriyama, Isoko
25
Takemura, Masaharu
15
Murakami, Chikako
14
Koiwai, Osamu
14
Hada, Takahiko
13
Kamisuki, Shinji
13
Yonezawa, Yuko
12
Takeuchi, Toshifumi
12
Shimazaki, Noriko
11
Oshige, Masahiko
11
Maeda, Naoki
9
Kasai, Nobuyuki
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All Publications
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2009: Matsui Yuki; Hada Takahiko; Maeda Naoki; Sato Yoshihiro; Yamaguchi Yasuhiro; Takeuchi Toshifumi; Takemura Masaharu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Structure and activity relationship of monogalactosyl diacylglycerols, which selectively inhibited in vitro mammalian replicative DNA polymerase activity and human cancer cell growth.
Cancer letters 2009;283(1):101-7.
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2009: Matsumoto Naoki; Yamada Mitsugu; Kurakata Yuma; Yoshida Hiromi; Kamitori Shigehiro; Nishikawa Atsushi; Tonozuka Takashi
Crystal structures of open and closed forms of cyclo/maltodextrin-binding protein.
The FEBS journal 2009;276(11):3008-19.
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2009: Kumamoto-Yonezawa Yuko; Sasaki Ryohei; Ota Yosuke; Suzuki Yoko; Fukushima Shoji; Hada Takahiko; Uryu Keisuke; Sugimura Kazuro; Yoshida Hiromi; Mizushina Yoshiyuki
Cell cycle arrest triggered by conjugated eicosapentaenoic acid occurs through several mechanisms including G1 checkpoint activation by induced RPA and ATR expression.
Biochimica et biophysica acta 2009;1790(5):339-46.
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2009: Kimura Takuma; Takeuchi Toshifumi; Kumamoto-Yonezawa Yuko; Ohashi Eiji; Ohmori Haruo; Masutani Chikahide; Hanaoka Fumio; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases.
Bioorganic & medicinal chemistry 2009;17(5):1811-6.
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2009: Mizushina Yoshiyuki; Manita Daisuke; Takeuchi Toshifumi; Sugawara Fumio; Kumamoto-Yonezawa Yuko; Matsui Yuki; Takemura Masaharu; Sasaki Mitsuru; Yoshida Hiromi; Takikawa Hirosato
The inhibitory action of kohamaic acid A derivatives on mammalian DNA polymerase beta.
Molecules (Basel, Switzerland) 2009;14(1):102-21.
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2008: Kuriyama Isoko; Fukudome Keishi; Kamisuki Shinji; Kuramochi Kouji; Tsubaki Kazunori; Sakaguchi Kengo; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase alpha.
International journal of molecular medicine 2008;22(6):793-9.
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2008: Maeda Naoki; Kokai Yasuo; Ohtani Seiji; Sahara Hiroeki; Kumamoto-Yonezawa Yuko; Kuriyama Isoko; Hada Takahiko; Sato Noriyuki; Yoshida Hiromi; Mizushina Yoshiyuki
Anti-tumor effect of orally administered spinach glycolipid fraction on implanted cancer cells, colon-26, in mice.
Lipids 2008;43(8):741-8.
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2008: Kurakata Yuma; Uechi Akiko; Yoshida Hiromi; Kamitori Shigehiro; Sakano Yoshiyuki; Nishikawa Atsushi; Tonozuka Takashi
Structural insights into the substrate specificity and function of Escherichia coli K12 YgjK, a glucosidase belonging to the glycoside hydrolase family 63.
Journal of molecular biology 2008;381(1):116-28.
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2008: Mizushina Yoshiyuki; Takeuchi Toshifumi; Hada Takahiko; Maeda Naoki; Sugawara Fumio; Yoshida Hiromi; Fujita Masatoshi
The inhibitory action of SQDG (sulfoquinovosyl diacylglycerol) from spinach on Cdt1-geminin interaction.
Biochimie 2008;90(6):947-56.
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2008: Nishida Masayuki; Ida Noriko; Horio Mao; Takeuchi Toshifumi; Kamisuki Shinji; Murata Hiroshi; Kuramochi Kouji; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Hymenoic acid, a novel specific inhibitor of human DNA polymerase lambda from a fungus of Hymenochaetaceae sp.
Bioorganic & medicinal chemistry 2008;16(9):5115-22.
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2008: Kimura Takuma; Nishida Masayuki; Kuramochi Kouji; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Novel azaphilones, kasanosins A and B, which are specific inhibitors of eukaryotic DNA polymerases beta and lambda from Talaromyces sp.
Bioorganic & medicinal chemistry 2008;16(8):4594-9.
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2008: Ishimaru Chisato; Yonezawa Yuko; Kuriyama Isoko; Nishida Masayuki; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effects of cholesterol derivatives on DNA polymerase and topoisomerase activities, and human cancer cell growth.
Lipids 2008;43(4):373-82.
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2008: Mizushina Yoshiyuki; Takeuchi Toshifumi; Takakusagi Yoichi; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Fujita Masatoshi
Inhibitory action of polyunsaturated fatty acids on Cdt1-geminin interaction.
International journal of molecular medicine 2008;21(3):281-90.
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2008: Naganuma Mitsuki; Nishida Masayuki; Kuramochi Kouji; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
1-deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae.
Bioorganic & medicinal chemistry 2008;16(6):2939-44.
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2008: Mizuno Masahiro; Koide Atsushi; Yamamura Akihiro; Akeboshi Hiromi; Yoshida Hiromi; Kamitori Shigehiro; Sakano Yoshiyuki; Nishikawa Atsushi; Tonozuka Takashi
Crystal structure of Aspergillus niger isopullulanase, a member of glycoside hydrolase family 49.
Journal of molecular biology 2008;376(1):210-20.
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2008: Mizushina Yoshiyuki; Takeuchi Toshifumi; Takakusagi Yoichi; Yonezawa Yuko; Mizuno Takeshi; Yanagi Ken-Ichiro; Imamoto Naoko; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Fujita Masatoshi
Coenzyme Q10 as a potent compound that inhibits Cdt1-geminin interaction.
Biochimica et biophysica acta 2008;1780(2):203-13.
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2008: Kuriyama Isoko; Mizuno Takeshi; Fukudome Keishi; Kuramochi Kouji; Tsubaki Kazunori; Usui Takeo; Imamoto Naoko; Sakaguchi Kengo; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells.
Molecules (Basel, Switzerland) 2008;13(12):2948-61.
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2007: Nakamura Ryoichi; Takeuchi Ryo; Kuramochi Kouji; Mizushina Yoshiyuki; Ishimaru Chisato; Takakusagi Yoichi; Takemura Masaharu; Kobayashi Susumu; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Chemical properties of fatty acid derivatives as inhibitors of DNA polymerases.
Organic & biomolecular chemistry 2007;5(24):3912-21.
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2007: Yonezawa Yuko; Hada Takahiko; Uryu Keisuke; Tsuzuki Tsuyoshi; Nakagawa Kiyotaka; Miyazawa Teruo; Yoshida Hiromi; Mizushina Yoshiyuki
Mechanism of cell cycle arrest and apoptosis induction by conjugated eicosapentaenoic acid, which is a mammalian DNA polymerase and topoisomerase inhibitor.
International journal of oncology 2007;30(5):1197-204.
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2007: Mizushina Yoshiyuki; Dairaku Issei; Yanaka Noriyuki; Takeuchi Toshifumi; Ishimaru Chisato; Sugawara Fumio; Yoshida Hiromi; Kato Norihisa
Inhibitory action of polyunsaturated fatty acids on IMP dehydrogenase.
Biochimie 2007;89(5):581-90.
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2007: Kamisuki Shinji; Ishimaru Chisato; Onoda Kadohiro; Kuriyama Isoko; Ida Noriko; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp.
Bioorganic & medicinal chemistry 2007;15(9):3109-14.
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2007: Tonozuka Takashi; Sogawa Akiko; Yamada Mitsugu; Matsumoto Naoki; Yoshida Hiromi; Kamitori Shigehiro; Ichikawa Kazuhiro; Mizuno Masahiro; Nishikawa Atsushi; Sakano Yoshiyuki
Structural basis for cyclodextrin recognition by Thermoactinomyces vulgaris cyclo/maltodextrin-binding protein.
The FEBS journal 2007;274(8):2109-20.
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2007: Ishimaru Chisato; Kuriyama Isoko; Shimazaki Noriko; Koiwai Osamu; Sakaguchi Kengo; Kato Ikuo; Yoshida Hiromi; Mizushina Yoshiyuki
Cholesterol hemisuccinate: a selective inhibitor of family X DNA polymerases.
Biochemical and biophysical research communications 2007;354(2):619-25.
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2007: Iijima Hiroshi; Kasai Nobuyuki; Chiku Hiroyuki; Takeuchi Toshifumi; Kuramochi Kouji; Hanashima Shinya; Kobayashi Susumu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Structure-activity relationship of a glycolipid, sulfoquinovosyl diacylglycerol, with the DNA binding activity of p53.
International journal of molecular medicine 2007;19(1):41-8.
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2007: Maeda Naoki; Kokai Yasuo; Ohtani Seiji; Sahara Hiroeki; Kuriyama Isoko; Kamisuki Shinji; Takahashi Shunya; Sakaguchi Kengo; Sugawara Fumio; Yoshida Hiromi; Sato Noriyuki; Mizushina Yoshiyuki
Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.
Biochemical and biophysical research communications 2007;352(2):390-6.
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2007: Maeda Naoki; Kokai Yasuo; Ohtani Seiji; Sahara Hiroeki; Hada Takahiko; Ishimaru Chisato; Kuriyama Isoko; Yonezawa Yuko; Iijima Hiroshi; Yoshida Hiromi; Sato Noriyuki; Mizushina Yoshiyuki
Anti-tumor effects of the glycolipids fraction from spinach which inhibited DNA polymerase activity.
Nutrition and cancer 2007;57(2):216-23.
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2007: Maeda Naoki; Hada Takahiko; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effect on replicative DNA polymerases, human cancer cell proliferation, and in vivo anti-tumor activity by glycolipids from spinach.
Current medicinal chemistry 2007;14(9):955-67.
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2006: Yonezawa Yuko; Hada Takahiko; Uryu Keisuke; Iijima Hiroshi; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory action of C22-fatty acids on DNA polymerases and DNA topoisomerases.
International journal of molecular medicine 2006;18(4):583-8.
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2006: Yonezawa Yuko; Kuriyama Isoko; Fukuoh Atsushi; Muta Tsuyoshi; Kang Dongchon; Takemura Masaharu; Kato Ikuo; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effect of coenzyme Q on eukaryotic DNA polymerase gamma and DNA topoisomerase II activities on the growth of a human cancer cell line.
Cancer science 2006;97(8):716-23.
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2006: Iijima Hiroshi; Kasai Nobuyuki; Chiku Hiroyuki; Murakami Shizuka; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
The inhibitory action of long-chain fatty acids on the DNA binding activity of p53.
Lipids 2006;41(6):521-7.
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2006: Mizushina Yoshiyuki; Nakanishi Rumi; Kuriyama Isoko; Kamiya Kohei; Satake Toshiko; Shimazaki Noriko; Koiwai Osamu; Uchiyama Yukinobu; Yonezawa Yuko; Takemura Masaharu; Sakaguchi Kengo; Yoshida Hiromi
Beta-sitosterol-3-O-beta-D-glucopyranoside: a eukaryotic DNA polymerase lambda inhibitor.
The Journal of steroid biochemistry and molecular biology 2006;99(2-3):100-7.
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2006: Iijima Hiroshi; Musumi Keiichi; Hada Takahiko; Maeda Naoki; Yonezawa Yuko; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effect of monogalactosyldiacylglycerol, extracted from spinach using supercritical CO2, on mammalian DNA polymerase activity.
Journal of agricultural and food chemistry 2006;54(5):1627-32.
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2006: Takeuchi Toshifumi; Ishidoh Tomomi; Iijima Hiroshi; Kuriyama Isoko; Shimazaki Noriko; Koiwai Osamu; Kuramochi Kouji; Kobayashi Susumu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(3):223-35.
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2006: Mizushina Yoshiyuki; Yagita Etsuko; Kuramochi Kouji; Kuriyama Isoko; Shimazaki Noriko; Koiwai Osamu; Uchiyama Yukinobu; Yomezawa Yuko; Sugawara Fumio; Kobayashi Susumu; Sakaguchi Kengo; Yoshida Hiromi
5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase.
Archives of biochemistry and biophysics 2006;446(1):69-76.
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2006: Mizushina Yoshiyuki; Nakagawa Kiyotaka; Shibata Akira; Awata Yasutoshi; Kuriyama Isoko; Shimazaki Noriko; Koiwai Osamu; Uchiyama Yukinobu; Sakaguchi Kengo; Miyazawa Teruo; Yoshida Hiromi
Inhibitory effect of tocotrienol on eukaryotic DNA polymerase lambda and angiogenesis.
Biochemical and biophysical research communications 2006;339(3):949-55.
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2005: Mizushina Yoshiyuki; Ishidoh Tomomi; Takeuchi Toshifumi; Shimazaki Noriko; Koiwai Osamu; Kuramochi Kouji; Kobayashi Susumu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi
Monoacetylcurcumin: a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography.
Biochemical and biophysical research communications 2005;337(4):1288-95.
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2005: Mizushina Yoshiyuki; Kasai Nobuyuki; Iijima Hiroshi; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
Sulfo-quinovosyl-acyl-glycerol (SQAG), a eukaryotic DNA polymerase inhibitor and anti-cancer agent.
Current medicinal chemistry. Anti-cancer agents 2005;5(6):613-25.
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2005: Kuriyama Isoko; Musumi Keiichi; Yonezawa Yuko; Takemura Masaharu; Maeda Naoki; Iijima Hiroshi; Hada Takahiko; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effects of glycolipids fraction from spinach on mammalian DNA polymerase activity and human cancer cell proliferation.
The Journal of nutritional biochemistry 2005;16(10):594-601.
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2005: Mizushina Yoshiyuki; Akihisa Toshihiro; Ukiya Motohiko; Hamasaki Yusuke; Murakami-Nakai Chikako; Kuriyama Isoko; Takeuchi Toshifumi; Sugawara Fumio; Yoshida Hiromi
Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors.
Life sciences 2005;77(17):2127-40.
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2005: Mizushina Yoshiyuki; Takikawa Hirosato; Imamura Yusuke; Sasaki Mitsuru; Mori Kenji; Yoshida Hiromi
Inhibitory effect of mispyric acid on mammalian DNA polymerases.
Bioscience, biotechnology, and biochemistry 2005;69(8):1534-8.
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2005: Yonezawa Yuko; Hada Takahiko; Uryu Keisuke; Tsuzuki Tsuyoshi; Eitsuka Takahiro; Miyazawa Teruo; Murakami-Nakai Chikako; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effect of conjugated eicosapentaenoic acid on mammalian DNA polymerase and topoisomerase activities and human cancer cell proliferation.
Biochemical pharmacology 2005;70(3):453-60.
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2005: Mizushina Yoshiyuki; Saito Akiko; Tanaka Akira; Nakajima Noriyuki; Kuriyama Isoko; Takemura Masaharu; Takeuchi Toshifumi; Sugawara Fumio; Yoshida Hiromi
Structural analysis of catechin derivatives as mammalian DNA polymerase inhibitors.
Biochemical and biophysical research communications 2005;333(1):101-9.
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2005: Mizushina Yoshiyuki; Kuramochi Kouji; Ikawa Hiroshi; Kuriyama Isoko; Shimazaki Noriko; Takemura Masaharu; Oshige Masahiko; Yoshida Hiromi; Koiwai Osamu; Sugawara Fumio; Kobayashi Susumu; Sakaguchi Kengo
Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds.
International journal of molecular medicine 2005;15(5):785-93.
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2005: Kuriyama Isoko; Asano Naoki; Kato Ikuo; Ikeda Kyoko; Takemura Masaharu; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Dipeptide alcohol-based inhibitors of eukaryotic DNA polymerase alpha.
Bioorganic & medicinal chemistry 2005;13(6):2187-96.
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2005: Yonezawa Yuko; Tsuzuki Tsuyoshi; Eitsuka Takahiro; Miyazawa Teruo; Hada Takahiko; Uryu Keisuke; Murakami-Nakai Chikako; Ikawa Hiroshi; Kuriyama Isoko; Takemura Masaharu; Oshige Masahiko; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Inhibitory effect of conjugated eicosapentaenoic acid on human DNA topoisomerases I and II.
Archives of biochemistry and biophysics 2005;435(1):197-206.
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2005: Maeda Naoki; Hada Takahiko; Murakami-Nakai Chikako; Kuriyama Isoko; Ichikawa Hideki; Fukumori Yoshinobu; Hiratsuka Junichi; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Effects of DNA polymerase inhibitory and antitumor activities of lipase-hydrolyzed glycolipid fractions from spinach.
The Journal of nutritional biochemistry 2005;16(2):121-8.
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2004: Mizushina Yoshiyuki; Tsuzuki Tsuyoshi; Eitsuka Takahiro; Miyazawa Teruo; Kobayashi Kanako; Ikawa Hiroshi; Kuriyama Isoko; Yonezawa Yuko; Takemura Masaharu; Yoshida Hiromi; Sakaguchi Kengo
Inhibitory action of conjugated C18-fatty acids on DNA polymerases and DNA topoisomerases.
Lipids 2004;39(10):977-83.
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2004: Murakami-Nakai Chikako; Maeda Naoki; Yonezawa Yuko; Kuriyama Isoko; Kamisuki Shinji; Takahashi Shunya; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
The effects of dehydroaltenusin, a novel mammalian DNA polymerase alpha inhibitor, on cell proliferation and cell cycle progression.
Biochimica et biophysica acta 2004;1674(2):193-9.
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2004: Mizushina Yoshiyuki; Kasai Nobuyuki; Miura Katsumi; Hanashima Shinya; Takemura Masaharu; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta.
Biochemistry 2004;43(33):10669-77.
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2004: Ogawa Akitsu; Murakami Chikako; Kamisuki Shinji; Kuriyama Isoko; Yoshida Hiromi; Sugawara Fumio; Mizushina Yoshiyuki
Pseudodeflectusin, a novel isochroman derivative from Aspergillus pseudodeflectus a parasite of the sea weed, Sargassum fusiform, as a selective human cancer cytotoxin.
Bioorganic & medicinal chemistry letters 2004;14(13):3539-43.
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2004: Mizushina Yoshiyuki; Akihisa Toshihiro; Ukiya Motohiko; Murakami Chikako; Kuriyama Isoko; Xu Xianai; Yoshida Hiromi; Sakaguchi Kengo
A novel DNA topoisomerase inhibitor: dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos.
Cancer science 2004;95(4):354-60.
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2004: Kuriyama Isoko; Asano Naoki; Kato Ikuo; Oshige Masahiko; Sugino Akio; Kadota Yasuhiro; Kuchitsu Kazuyuki; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
L-Homoserylaminoethanol, a novel dipeptide alcohol inhibitor of eukaryotic DNA polymerase from a plant cultured cells, Nicotina tabacum L.
Bioorganic & medicinal chemistry 2004;12(5):957-62.
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2003: Mizushina Yoshiyuki; Xu Xianai; Matsubara Kiminori; Murakami Chikako; Kuriyama Isoko; Oshige Masahiko; Takemura Masaharu; Kato Norihisa; Yoshida Hiromi; Sakaguchi Kengo
Pyridoxal 5'-phosphate is a selective inhibitor in vivo of DNA polymerase alpha and epsilon.
Biochemical and biophysical research communications 2003;312(4):1025-32.
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2003: Mizushina Yoshiyuki; Hirota Mitsuru; Murakami Chikako; Ishidoh Tomomi; Kamisuki Shinji; Shimazaki Noriko; Takemura Masaharu; Perpelescu Marinela; Suzuki Motoshi; Yoshida Hiromi; Sugawara Fumio; Koiwai Osamu; Sakaguchi Kengo
Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors.
Biochemical pharmacology 2003;66(10):1935-44.
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2003: Mizushina Yoshiyuki; Maeda Naoki; Kawasaki Miho; Ichikawa Hideki; Murakami Chikako; Takemura Masaharu; Xu Xianai; Sugawara Fumio; Fukumori Yoshinobu; Yoshida Hiromi; Sakaguchi Kengo
Inhibitory action of emulsified sulfoquinovosyl acylglycerol on mammalian DNA polymerases.
Lipids 2003;38(10):1065-74.
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2003: Murakami Chikako; Takemura Masaharu; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
Analysis of cell cycle regulation by 1-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride (SQMG), an inhibitor of eukaryotic DNA polymerases.
Biochemical pharmacology 2003;66(4):541-50.
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2003: Mizushina Yoshiyuki; Xu Xianai; Murakami Chikako; Okano Toshio; Takemura Masaharu; Yoshida Hiromi; Sakaguchi Kengo
Selective inhibition of mammalian DNA polymerase alpha by vitamin D2 and D3.
Journal of pharmacological sciences 2003;92(3):283-90.
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2003: Mizushina Yoshiyuki; Murakami Chikako; Yogi Kentaro; Ueda Katsuhiro; Ishidoh Tomomi; Takemura Masaharu; Perpelescu Marinela; Suzuki Motoshi; Oshige Masahiko; Yamaguchi Toyofumi; Saneyoshi Mineo; Yoshida Hiromi; Sakaguchi Kengo
Kohamaic acid A, a novel sesterterpenic acid, inhibits activities of DNA polymerases from deuterostomes.
Biochimica et biophysica acta 2003;1648(1-2):55-61.
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2003: Mizushina Yoshiyuki; Ikuta Akira; Endoh Kenji; Oshige Masahiko; Kasai Nobuyuki; Kamiya Kohei; Satake Toshiko; Takazawa Hiroshi; Morita Hiromasa; Tomiyasu Hiroaki; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Inhibition of DNA polymerases and DNA topoisomerase II by triterpenes produced by plant callus.
Biochemical and biophysical research communications 2003;305(2):365-73.
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2003: Mizushina Yoshiyuki; Murakami Chikako; Takikawa Hirosato; Kasai Nobuyuki; Xu Xianai; Mori Kenji; Oshige Masahiko; Yamaguchi Toyofumi; Saneyoshi Mineo; Shimazaki Noriko; Koiwai Osamu; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Molecular action mode of Hippospongic acid A, an inhibitor of gastrulation of starfish embryos.
Journal of biochemistry 2003;133(4):541-52.
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2003: Mizushina Yoshiyuki; Xu Xianai; Asano Naoki; Kasai Nobuyuki; Kato Atsushi; Takemura Masaharu; Asahara Hitomi; Linn Stuart; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
The inhibitory action of pyrrolidine alkaloid, 1,4-dideoxy-1,4-imino-D-ribitol, on eukaryotic DNA polymerases.
Biochemical and biophysical research communications 2003;304(1):78-85.
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2003: Mizushina Yoshiyuki; Ishidoh Tomomi; Kamisuki Shinji; Nakazawa Satoshi; Takemura Masaharu; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
Flavonoid glycoside: a new inhibitor of eukaryotic DNA polymerase alpha and a new carrier for inhibitor-affinity chromatography.
Biochemical and biophysical research communications 2003;301(2):480-7.
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2003: Mizushina Yoshiyuki; Xu Xianai; Asahara Hitomi; Takeuchi Ryo; Oshige Masahiko; Shimazaki Noriko; Takemura Masaharu; Yamaguchi Toyofumi; Kuroda Kazufumi; Linn Stuart; Yoshida Hiromi; Koiwai Osamu; Saneyoshi Mineo; Sugawara Fumio; Sakaguchi Kengo
A sulphoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor.
The Biochemical journal 2003;370(Pt 1):299-305.
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2003: Murakami Chikako; Yamazaki Takayuki; Hanashima Shinya; Takahashi Shunya; Takemura Masaharu; Yoshida Shonen; Ohta Keisuke; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid.
Biochimica et biophysica acta 2003;1645(1):72-80.
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2003: Murakami Chikako; Kumagai Taeko; Hada Takahiko; Kanekazu Ui; Nakazawa Satoshi; Kamisuki Shinji; Maeda Naoki; Xu Xianai; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
Effects of glycolipids from spinach on mammalian DNA polymerases.
Biochemical pharmacology 2003;65(2):259-67.
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2002: Mizushina Yoshiyuki; Kamisuki Shinji; Kasai Nobuyuki; Ishidoh Tomomi; Shimazaki Noriko; Takemura Masaharu; Asahara Hitomi; Linn Stuart; Yoshida Shonen; Koiwai Osamu; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
Petasiphenol: a DNA polymerase lambda inhibitor.
Biochemistry 2002;41(49):14463-71.
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2002: Murakami Chikako; Yamazaki Takayuki; Hanashima Shinya; Takahashi Shunya; Ohta Keisuke; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
Structure-function relationship of synthetic sulfoquinovosyl-acylglycerols as mammalian DNA polymerase inhibitors.
Archives of biochemistry and biophysics 2002;403(2):229-36.
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2002: Murakami Chikako; Ishijima Kiyomi; Hirota Mitsuru; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases.
Biochimica et biophysica acta 2002;1596(2):193-200.
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2002: Murakami Chikako; Takemura Masaharu; Sugiyama Yuichi; Kamisuki Shinji; Asahara Hitomi; Kawasaki Miho; Ishidoh Tomomi; Linn Stuart; Yoshida Shonen; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases.
Biochimica et biophysica acta 2002;1574(1):85-92.
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2002: Kamisuki Shinji; Murakami Chikako; Ohta Keisuke; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
Actions of derivatives of dehydroaltenusin, a new mammalian DNA polymerase alpha-specific inhibitor.
Biochemical pharmacology 2002;63(3):421-7.
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2002: Mizushina Yoshiyuki; Murakami Chikako; Ohta Keisuke; Takikawa Hirosato; Mori Kenji; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Selective inhibition of the activities of both eukaryotic DNA polymerases and DNA topoisomerases by elenic acid.
Biochemical pharmacology 2002;63(3):399-407.
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2002: Watanabe Madoka; Hanashima Shinya; Mizushina Yoshiyuki; Yoshida Hiromi; Oshige Masahiko; Sakaguchi Kengo; Sugawara Fumio
Biotinylated lithocholic acids for affinity chromatography of mammalian DNA polymerases alpha and beta.
Bioorganic & medicinal chemistry letters 2002;12(3):287-90.
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2002: Mizushina Yoshiyuki; Kamisuki Shinji; Kasai Nobuyuki; Shimazaki Noriko; Takemura Masaharu; Asahara Hitomi; Linn Stuart; Yoshida Shonen; Matsukage Akio; Koiwai Osamu; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda.
The Journal of biological chemistry 2002;277(1):630-8.
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2001: Mizushina Y; Kasai N; Sugawara F; Iida A; Yoshida H; Sakaguchi K
Three-dimensional structural model analysis of the binding site of lithocholic acid, an inhibitor of DNA polymerase beta and DNA topoisomerase II.
Journal of biochemistry 2001;130(5):657-64.
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2001: Takata K; Yoshida H; Hirose F; Yamaguchi M; Kai M; Oshige M; Sakimoto I; Koiwai O; Sakaguchi K
Drosophila mitochondrial transcription factor A: characterization of its cDNA and expression pattern during development.
Biochemical and biophysical research communications 2001;287(2):474-83.
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2000: Oshige M; Yoshida H; Hirose F; Takata K I; Inoue Y; Aoyagi N; Yamaguchi M; Koiwai O; Matsukage A; Sakaguchi K
Molecular cloning and expression during development of the Drosophila gene for the catalytic subunit of DNA polymerase epsilon.
Gene 2000;256(1-2):93-100.
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