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Kanji Yoshida

Research Profile

Chemicals & Drugs

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Signal Transduction

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Atsushi Kumanogoh; Satoko Marukawa; Kazuhiro Suzuki; Noriko Takegahara; Chie Watanabe; Ewe Seng Ch'ng; Isao Ishida; Harutoshi Fujimura; Saburo Sakoda; Kanji Yoshida; Hitoshi Kikutani
Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2.
Atsushi Kumanogoh; Kazuhiro Suzuki; Ewe Seng Ch'ng; Chie Watanabe; Satoko Marukawa; Noriko Takegahara; Isao Ishida; Takehito Sato; Sonoko Habu; Kanji Yoshida; Wei Shi; Hitoshi Kikutani
Requirement for the lymphocyte semaphorin, CD100, in the induction of antigen-specific T cells and the maturation of dendritic cells.
Chie Watanabe; Atsushi Kumanogoh; Wei Shi; Kazuhiro Suzuki; S Yamada; Masaru Okabe; Kanji Yoshida; Hitoshi Kikutani
Enhanced immune responses in transgenic mice expressing a truncated form of the lymphocyte semaphorin CD100.

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All Publications

2002: Atsushi Kumanogoh; Satoko Marukawa; Kazuhiro Suzuki; Noriko Takegahara; Chie Watanabe; Ewe Seng Ch'ng; Isao Ishida; Harutoshi Fujimura; Saburo Sakoda; Kanji Yoshida; Hitoshi Kikutani
Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2.
Nature 2002;419(6907):629-33.
2002: Atsushi Kumanogoh; Kazuhiro Suzuki; Ewe Seng Ch'ng; Chie Watanabe; Satoko Marukawa; Noriko Takegahara; Isao Ishida; Takehito Sato; Sonoko Habu; Kanji Yoshida; Wei Shi; Hitoshi Kikutani
Requirement for the lymphocyte semaphorin, CD100, in the induction of antigen-specific T cells and the maturation of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1175-81.
2001: Chie Watanabe; Atsushi Kumanogoh; Wei Shi; Kazuhiro Suzuki; S Yamada; Masaru Okabe; Kanji Yoshida; Hitoshi Kikutani
Enhanced immune responses in transgenic mice expressing a truncated form of the lymphocyte semaphorin CD100.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4321-8.
2001: X Wang; Atsushi Kumanogoh; Chie Watanabe; Wei Shi; Kanji Yoshida; Hitoshi Kikutani
Functional soluble CD100/Sema4D released from activated lymphocytes: possible role in normal and pathologic immune responses.
Blood 2001;97(11):3498-504.
2001: Atsushi Kumanogoh; X Wang; I Lee; Chie Watanabe; Masato Kamanaka; Wei Shi; Kanji Yoshida; Takehito Sato; Sonoko Habu; Motoyuki Itoh; N Sakaguchi; S Sakaguchi; Hitoshi Kikutani
Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: a role of CD40 in regulatory T cell development.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):353-60.
2000: Wei Shi; Atsushi Kumanogoh; Chie Watanabe; Junji Uchida; X Wang; Teruhito Yasui; Kazunori Yukawa; M Ikawa; Masaru Okabe; Jane R Parnes; Kanji Yoshida; Hitoshi Kikutani
The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient mice.
Immunity 2000;13(5):633-42.
2000: Atsushi Kumanogoh; Chie Watanabe; I Lee; X Wang; Wei Shi; H Araki; H Hirata; Kota Iwahori; Junji Uchida; Teruhito Yasui; Makoto Matsumoto; Kanji Yoshida; Hidetaka Yakura; C Pan; Jane R Parnes; Hitoshi Kikutani
Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling.
Immunity 2000;13(5):621-31.
1998: X J Wang; Tetsuya Taga; Kanji Yoshida; M Saito; Tadamitsu Kishimoto; Hitoshi Kikutani
gp130, the cytokine common signal-transducer of interleukin-6 cytokine family, is downregulated in T cells in vivo by interleukin-6.
Blood 1998;91(9):3308-14.
1997: Atsushi Kumanogoh; Satoko Marukawa; T Kumanogoh; Hisao Hirota; Kanji Yoshida; I S Lee; T Yasui; K Yoshida; T Taga; Tadamitsu Kishimoto
Impairment of antigen-specific antibody production in transgenic mice expressing a dominant-negative form of gp130.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2478-82.
1996: D Watanabe; R Yoshimura; M Khalil; Kanji Yoshida; Tadamitsu Kishimoto; Tetsuya Taga; Hiroshi Kiyama
Characteristic localization of gp130 (the signal-transducing receptor component used in common for IL-6/IL-11/CNTF/LIF/OSM) in the rat brain.
The European journal of neuroscience 1996;8(8):1630-40.
1996: Jennifer Nichols; D Davidson; Tetsuya Taga; Kanji Yoshida; Ian Chambers; Austin Smith
Complementary tissue-specific expression of LIF and LIF-receptor mRNAs in early mouse embryogenesis.
Mechanisms of development 1996;57(2):123-31.
1996: Hisao Hirota; Kanji Yoshida; Tetsuya Taga; Tadamitsu Kishimoto
gp130 signaling pathways: Recent advances and implications for cardiovascular disease.
Trends in cardiovascular medicine 1996;6(4):109-15.
1996: Kanji Yoshida; Tetsuya Taga; M Saito; Sachiko Suematsu; A Kumanogoh; T Tanaka; Hiromi Fujiwara; M Hirata; T Yamagami; T Nakahata; T Hirabayashi; Yoshihiro Yoneda; K Tanaka; W Z Wang; C Mori; K Shiota; N Yoshida; Tadamitsu Kishimoto
Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):407-11.
1995: S Akira; Kanji Yoshida; T Tanaka; Tetsuya Taga; Tadamitsu Kishimoto
Targeted disruption of the IL-6 related genes: gp130 and NF-IL-6.
Immunological reviews 1995;148():221-53.
1995: Kanji Yoshida; T Kasai; M R Garcia; S Sawada; T Shoji; S Shimizu; K Yamazaki; Y Komeda; A Shinmyo
Heat-inducible expression system for a foreign gene in cultured tobacco cells using the HSP18.2 promoter of Arabidopsis thaliana.
Applied microbiology and biotechnology 1995;44(3-4):466-72.
1995: Tadamitsu Kishimoto; T Tanaka; Kanji Yoshida; S Akira; Tetsuya Taga
Cytokine signal transduction through a homo- or heterodimer of gp130.
Annals of the New York Academy of Sciences 1995;766():224-34.
1995: Hisao Hirota; Kanji Yoshida; Tadamitsu Kishimoto; Tetsuya Taga
Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):4862-6.
1995: T Tanaka; S Akira; Kanji Yoshida; M Umemoto; Yoshihiro Yoneda; N Shirafuji; H Fujiwara; Sachiko Suematsu; N Yoshida; Tadamitsu Kishimoto
Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages.
Cell 1995;80(2):353-61.
1994: A Kawaoka; T Kawamoto; M Sekine; Kanji Yoshida; M Takano; A Shinmyo
A cis-acting element and a trans-acting factor involved in the wound-induced expression of a horseradish peroxidase gene.
The Plant journal : for cell and molecular biology 1994;6(1):87-97.
1994: Kanji Yoshida; T Ito; H Nozawa; J Ohkawa; A Shinmyo
Sequence requirement of 5'-upstream region of the ascorbate oxidase gene for organ-specific expression in cucumber.
Annals of the New York Academy of Sciences 1994;721():245-7.
1994: S Akira; Y Nishio; M Inoue; X J Wang; S Wei; T Matsusaka; Kanji Yoshida; T Sudo; M Naruto; Tadamitsu Kishimoto
Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway.
Cell 1994;77(1):63-71.
1994: Michiko Narazaki; bruce witthuhn; Kanji Yoshida; O Silvennoinen; K Yasukawa; James N Ihle; Tadamitsu Kishimoto; Tetsuya Taga
Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2285-9.
1994: Kanji Yoshida; Ian Chambers; Jennifer Nichols; Austin Smith; M Saito; K Yasukawa; M Shoyab; Tetsuya Taga; Tadamitsu Kishimoto
Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways.
Mechanisms of development 1994;45(2):163-71.
1992: M Saito; Kanji Yoshida; Masahiko Hibi; Tetsuya Taga; Tadamitsu Kishimoto
Molecular cloning of a murine IL-6 receptor-associated signal transducer, gp130, and its regulated expression in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(12):4066-71.