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Masayuki Yoshikawa

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Toshio Morikawa; Yoshinobu Miki; Sohachiro Miyake; Kiyofumi Ninomiya; Masaki Okamoto; Masayuki Yoshikawa; Osamu Muraoka
Flavonol glycosides with lipid accumulation inhibitory activity and simultaneous quantitative analysis of 15 polyphenols and caffeine in the flower buds of Camellia sinensis from different regions by LCMS.
Seikou Nakamura; Souichi Nakashima; Shino Nishida; Yoshimi Oda; Keiko Ogawa; Tomoe Ohta; Nami Yokota; Katsuyoshi Fujimoto; Sayuri Maeda; Hisashi Matsuda; Takahiro Matsumoto; Masayuki Yoshikawa
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
Seikou Nakamura; Souichi Nakashima; Shino Nishida; Yoshimi Oda; Keiko Ogawa; Tomoe Ohta; Rika Sakuma; Genzoh Tanabe; Nami Yokota; Katsuyoshi Fujimoto; Hisashi Matsuda; Takahiro Matsumoto; Hisako Miki; Osamu Muraoka; Masayuki Yoshikawa
Alkaloid constituents from flower buds and leaves of sacred lotus (Nelumbo nucifera, Nymphaeaceae) with melanogenesis inhibitory activity in B16 melanoma cells.

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2013: Toshio Morikawa; Yoshinobu Miki; Sohachiro Miyake; Kiyofumi Ninomiya; Masaki Okamoto; Masayuki Yoshikawa; Osamu Muraoka
Flavonol glycosides with lipid accumulation inhibitory activity and simultaneous quantitative analysis of 15 polyphenols and caffeine in the flower buds of Camellia sinensis from different regions by LCMS.
Food chemistry 2013;140(1-2):353-60.
2013: Seikou Nakamura; Souichi Nakashima; Shino Nishida; Yoshimi Oda; Keiko Ogawa; Tomoe Ohta; Nami Yokota; Katsuyoshi Fujimoto; Sayuri Maeda; Hisashi Matsuda; Takahiro Matsumoto; Masayuki Yoshikawa
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
Bioorganic & medicinal chemistry 2013;21(5):1043-9.
2013: Seikou Nakamura; Souichi Nakashima; Shino Nishida; Yoshimi Oda; Keiko Ogawa; Tomoe Ohta; Rika Sakuma; Genzoh Tanabe; Nami Yokota; Katsuyoshi Fujimoto; Hisashi Matsuda; Takahiro Matsumoto; Hisako Miki; Osamu Muraoka; Masayuki Yoshikawa
Alkaloid constituents from flower buds and leaves of sacred lotus (Nelumbo nucifera, Nymphaeaceae) with melanogenesis inhibitory activity in B16 melanoma cells.
Bioorganic & medicinal chemistry 2013;21(3):779-87.
2013: Katsuyoshi Fujimoto; Hisashi Matsuda; Takahiro Matsumoto; Seikou Nakamura; Keiko Ogawa; Tomoe Ohta; Haruka Tamura; Masayuki Yoshikawa
Medicinal flowers. XXXVIII. structures of acylated sucroses and inhibitory effects of constituents on aldose reducatase from the flower buds of Prunus mume.
Chemical & pharmaceutical bulletin 2013;61(4):445-51.
2012: Yuan-Yuan Xie; Masayuki Yoshikawa; Jia-Lin Qu; Qi-Long Wang; Yan Wang; Dan Yuan
Comparative evaluation of cultivars of Chrysanthemum morifolium flowers by HPLC-DAD-ESI/MS analysis and antiallergic assay.
Journal of agricultural and food chemistry 2012;60(51):12574-83.
2012: Genzoh Tanabe; Nozomi Tsutsui; Xiaoming Wu; Weijia Xie; Masayuki Yoshikawa; Masahiro Yoshinaga; Mumen F A Amer; Kanjyun Matsuoka; Shinya Nakamura; Isao Nakanishi; Osamu Muraoka
Role of the side chain stereochemistry in the α-glucosidase inhibitory activity of kotalanol, a potent natural α-glucosidase inhibitor. Part 2.
Bioorganic & medicinal chemistry 2012;20(21):6321-34.
2012: Toshio Morikawa; Yoshinobu Miki; Sohachiro Miyake; Kiyofumi Ninomiya; Masayuki Yoshikawa; Osamu Muraoka
Quantitative analysis of acylated oleanane-type triterpene saponins, chakasaponins I-III and floratheasaponins A-F, in the flower buds of Camellia sinensis from different regional origins.
Journal of natural medicines 2012;66(4):608-13.
2012: Genzoh Tanabe; Satoshi Tsuchiya; Nozomi Tsutsui; Weijia Xie; Masayuki Yoshikawa; Junji Akaki; Gorre Balakishan; Toshio Morikawa; Shinya Nakamura; Isao Nakanishi; Kiyofumi Ninomiya; Osamu Muraoka
In silico design, synthesis and evaluation of 3'-O-benzylated analogs of salacinol, a potent α-glucosidase inhibitor isolated from an Ayurvedic traditional medicine "Salacia".
Chemical communications (Cambridge, England) 2012;48(69):8646-8.
2012: Seikou Nakamura; Tomoe Ohta; Sunmi Park; Katsuyoshi Fujimoto; Hisashi Matsuda; Takahiro Matsumoto; Toshitsugu Moriura; Masayuki Yoshikawa
Melanogenesis inhibitory and fibroblast proliferation accelerating effects of noroleanane- and oleanane-type triterpene oligoglycosides from the flower buds of Camellia japonica.
Journal of natural products 2012;75(8):1425-30.
2012: Toshio Morikawa; Saowanee Chaipech; Takao Hayakawa; Hisashi Matsuda; Tomoko Matsumoto; Kiyofumi Ninomiya; Yukiko Nomura; Yutana Pongpiriyadacha; Mayumi Sueyoshi; Mikuko Yabe; Masayuki Yoshikawa; Osamu Muraoka
Suppressive effects of coumarins from Mammea siamensis on inducible nitric oxide synthase expression in RAW264.7 cells.
Bioorganic & medicinal chemistry 2012;20(16):4968-77.
2012: Toshio Morikawa; Saowanee Chaipech; Makoto Hamao; Takao Hayakawa; Hisashi Matsuda; Kiyofumi Ninomiya; Yutana Pongpiriyadacha; Hiroki Sato; Haruka Tamura; Yohei Umeda; Masayuki Yoshikawa; Osamu Muraoka
Anti-hyperlipidemic constituents from the bark of Shorea roxburghii.
Journal of natural medicines 2012;66(3):516-24.
2012: Saowanee Chaipech; Takao Hayakawa; Toshio Morikawa; Kiyofumi Ninomiya; Yutana Pongpiriyadacha; Masayuki Yoshikawa; Osamu Muraoka
New flav-3-en-3-ol glycosides, kaempferiaosides C and D, and acetophenone glycosides, kaempferiaosides E and F, from the rhizomes of Kaempferia parviflora.
Journal of natural medicines 2012;66(3):486-92.
2012: Toshio Morikawa; Saowanee Chaipech; Makoto Hamao; Takao Hayakawa; Haruka Kon'i; Hisashi Matsuda; Kiyofumi Ninomiya; Yutana Pongpiriyadacha; Hiroki Sato; Haruka Tamura; Yohei Umeda; Masayuki Yoshikawa; Osamu Muraoka
Antidiabetogenic oligostilbenoids and 3-ethyl-4-phenyl-3,4-dihydroisocoumarins from the bark of Shorea roxburghii.
Bioorganic & medicinal chemistry 2012;20(2):832-40.
2012: Katsuyoshi Fujimoto; Hisashi Matsuda; Takahiro Matsumoto; Tomoko Miura; Seikou Nakamura; Souichi Nakashima; Tomoe Ohta; Kaoru Uno; Masayuki Yoshikawa
Medicinal flowers. XXXV. Nor-oleanane-type and acylated oleanane-type triterpene saponins from the flower buds of Chinese Camellia japonica and their inhibitory effects on melanogenesis.
Chemical & pharmaceutical bulletin 2012;60(9):1188-94.
2012: Seikou Nakamura; Souichi Nakashima; Kaoru Uno; Katsuyoshi Fujimoto; Hisashi Matsuda; Takahiro Matsumoto; Tomoko Miura; Masayuki Yoshikawa
Medicinal flowers. XXXVI.1) Acylated oleanane-type triterpene saponins with inhibitory effects on melanogenesis from the flower buds of Chinese Camellia japonica.
Chemical & pharmaceutical bulletin 2012;60(6):752-8.
2012: Hisashi Matsuda; Megumi Murata; Seikou Nakamura; Makoto Hamao; Haruka Kon'i; Masayuki Yoshikawa
Medicinal flowers. XXXIII. Anti-hyperlipidemic and anti-hyperglycemic effects of chakasaponins I-III and structure of chakasaponin IV from flower buds of Chinese tea plant (Camellia sinensis).
Chemical & pharmaceutical bulletin 2012;60(5):674-80.
2012: Mohamed-Elamir F Hegazy; Hisashi Matsuda; Tomoko Matsumoto; Seikou Nakamura; Mikuko Yabe; Masayuki Yoshikawa
Sesquiterpenes from an Egyptian herbal medicine, Pulicaria undulate, with inhibitory effects on nitric oxide production in RAW264.7 macrophage cells.
Chemical & pharmaceutical bulletin 2012;60(3):363-70.
2012: Toshio Morikawa; Osamu Muraoka; Kiyofumi Ninomiya; Chihiro Yamashita; Takao Hayakawa; Katsuya Imura; Hisashi Matsuda; Sohachiro Miyake; Masayuki Yoshikawa
Promoting the effect of chemical constituents from the flowers of Poacynum hendersonii on adipogenesis in 3T3-L1 cells.
Journal of natural medicines 2012;66(1):39-48.
2011: Ghazi Hussein; Hisashi Matsuda; Seikou Nakamura; Kouhei Tamura; Toshihito Akiyama; Masayuki Yoshikawa
Protective and ameliorative effects of maté (Ilex paraguariensis) on metabolic syndrome in TSOD mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2011;19(1):88-97.
2011: Makoto Hamao; Saori Maekubo; Hisashi Matsuda; Seikou Nakamura; Souichi Nakashima; Shunsuke Semura; Sachiyo Wakasugi; Masayuki Yoshikawa
Anti-obesity effects of the methanolic extract and chakasaponins from the flower buds of Camellia sinensis in mice.
Bioorganic & medicinal chemistry 2011;19(20):6033-41.
2011: Genzoh Tanabe; Tetsu Otani; Wenying Cong; Toshie Minematsu; Kiyofumi Ninomiya; Masayuki Yoshikawa; Osamu Muraoka
Biological evaluation of 3'-O-alkylated analogs of salacinol, the role of hydrophobic alkyl group at 3' position in the side chain on the α-glucosidase inhibitory activity.
Bioorganic & medicinal chemistry letters 2011;21(10):3159-62.
2011: Hisashi Matsuda; Yuichiro Kogami; Seikou Nakamura; Tomomi Sugiyama; Tsubasa Ueno; Masayuki Yoshikawa
Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells.
Bioorganic & medicinal chemistry 2011;19(9):2835-41.
2011: Ghazi Hussein; Hisashi Matsuda; Seikou Nakamura; Kouhei Tamura; Toshihito Akiyama; Makoto Hamao; Masayuki Yoshikawa
Mate tea (Ilex paraguariensis) promotes satiety and body weight lowering in mice: involvement of glucagon-like peptide-1.
Biological & pharmaceutical bulletin 2011;34(12):1849-55.
2011: Toshio Morikawa; Osamu Muraoka; Seikou Nakamura; Kiyofumi Ninomiya; Eriko Nishida; Makoto Hamao; Takao Hayakawa; Xuezheng Li; Hisashi Matsuda; Masayuki Yoshikawa
Medicinal Flowers. XXXII. Structures of oleanane-type triterpene saponins, perennisosides VIII, IX, X, XI, and XII, from the flowers of Bellis perennis.
Chemical & pharmaceutical bulletin 2011;59(7):889-95.
2011: Seikou Nakamura; Hisashi Matsuda; Masayuki Yoshikawa
[Search for antidiabetic constituents of medicinal food].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2011;131(6):909-15.
2011: Osamu Muraoka; Toshio Morikawa; Sohachiro Miyake; Junji Akaki; Kiyofumi Ninomiya; Yutana Pongpiriyadacha; Masayuki Yoshikawa
Quantitative analysis of neosalacinol and neokotalanol, another two potent α-glucosidase inhibitors from Salacia species, by LC-MS with ion pair chromatography.
Journal of natural medicines 2011;65(1):142-8.
2011: Toshio Morikawa; Hideo Oominami; Hisashi Matsuda; Masayuki Yoshikawa
New terpenoids, olibanumols D-G, from traditional Egyptian medicine olibanum, the gum-resin of Boswellia carterii.
Journal of natural medicines 2011;65(1):129-34.
2010: Hisashi Matsuda; Seikou Nakamura; Katsuyoshi Fujimoto; Ryo Moriuchi; Yuta Kimura; Noriko Ikoma; Yuki Hata; Osamu Muraoka; Masayuki Yoshikawa
Medicinal Flowers. XXXI. Acylated oleanane-type triterpene saponins, Sasanquasaponins I-V, with antiallergic activity from the flower buds of Camellia sasanqua.
Chemical & pharmaceutical bulletin 2010;58(12):1617-21.
2010: Toshio Morikawa; Hideo Oominami; Hisashi Matsuda; Masayuki Yoshikawa
Four new ursane-type triterpenes, olibanumols K, L, M, and N, from traditional egyptian medicine olibanum, the gum-resin of Boswellia carterii.
Chemical & pharmaceutical bulletin 2010;58(11):1541-4.
2010: Toshio Morikawa; Yingni Pan; Kiyofumi Ninomiya; Katsuya Imura; Dan Yuan; Masayuki Yoshikawa; Takao Hayakawa; Osamu Muraoka
Iridoid and acyclic monoterpene glycosides, kankanosides L, M, N, O, and P from Cistanche tubulosa.
Chemical & pharmaceutical bulletin 2010;58(10):1403-7.
2010: Toshio Morikawa; Fengming Xu; Hisashi Matsuda; Masayuki Yoshikawa
Structures of novel norstilbene dimer, longusone A, and three new stilbene dimers, longusols A, B, and C, with antiallergic and radical scavenging activities from Egyptian natural medicine Cyperus longus.
Chemical & pharmaceutical bulletin 2010;58(10):1379-85.
2010: Osamu Muraoka; Toshio Morikawa; Sohachiro Miyake; Junji Akaki; Kiyofumi Ninomiya; Masayuki Yoshikawa
Quantitative determination of potent alpha-glucosidase inhibitors, salacinol and kotalanol, in Salacia species using liquid chromatography-mass spectrometry.
Journal of pharmaceutical and biomedical analysis 2010;52(5):770-3.
2010: Toshio Morikawa; Yuanyuan Xie; Kiyofumi Ninomiya; Masaki Okamoto; Osamu Muraoka; Dan Yuan; Masayuki Yoshikawa; Takao Hayakawa
Inhibitory effects of acylated acyclic sesquiterpene oligoglycosides from the pericarps of Sapindus rarak on tumor necrosis factor-alpha-induced cytotoxicity.
Chemical & pharmaceutical bulletin 2010;58(9):1276-80.
2010: Shinya Nakamura; Kazunori Takahira; Genzoh Tanabe; Toshio Morikawa; Mika Sakano; Kiyofumi Ninomiya; Masayuki Yoshikawa; Osamu Muraoka; Isao Nakanishi
Docking and SAR studies of salacinol derivatives as alpha-glucosidase inhibitors.
Bioorganic & medicinal chemistry letters 2010;20(15):4420-3.
2010: Toshio Morikawa; Osamu Muraoka; Masayuki Yoshikawa
[Pharmaceutical food science: search for anti-obese constituents from medicinal foods-anti-hyperlipidemic saponin constituents from the flowers of Bellis perennis].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2010;130(5):673-8.
2010: Hisashi Matsuda; Souichi Nakashima; Osama Bashir Abdel-Halim; Toshio Morikawa; Masayuki Yoshikawa
Cucurbitane-type triterpenes with anti-proliferative effects on U937 cells from an egyptian natural medicine, Bryonia cretica: structures of new triterpene glycosides, bryoniaosides A and B.
Chemical & pharmaceutical bulletin 2010;58(5):747-51.
2010: Seikou Nakamura; Gang Chen; Souichi Nakashima; Hisashi Matsuda; Yuehu Pei; Masayuki Yoshikawa
Brazilian natural medicines. IV. New noroleanane-type triterpene and ecdysterone-type sterol glycosides and melanogenesis inhibitors from the roots of Pfaffia glomerata.
Chemical & pharmaceutical bulletin 2010;58(5):690-5.
2010: Souichi Nakashima; Hisashi Matsuda; Ai Kurume; Yoshimi Oda; Seikou Nakamura; Masayuki Yamashita; Masayuki Yoshikawa
Cucurbitacin E as a new inhibitor of cofilin phosphorylation in human leukemia U937 cells.
Bioorganic & medicinal chemistry letters 2010;20(9):2994-7.
2010: Souichi Nakashima; Hisashi Matsuda; Yoshimi Oda; Seikou Nakamura; Fengming Xu; Masayuki Yoshikawa
Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells.
Bioorganic & medicinal chemistry 2010;18(6):2337-45.
2010: Toshio Morikawa; Yingni Pan; Kiyofumi Ninomiya; Katsuya Imura; Hisashi Matsuda; Masayuki Yoshikawa; Dan Yuan; Osamu Muraoka
Acylated phenylethanoid oligoglycosides with hepatoprotective activity from the desert plant Cistanche tubulosa.
Bioorganic & medicinal chemistry 2010;18(5):1882-90.
2009: Toshio Morikawa; Itadaki Yamaguchi; Hisashi Matsuda; Masayuki Yoshikawa
A new amide, piperchabamide F, and two new phenylpropanoid glycosides, piperchabaosides A and B, from the fruit of Piper chaba.
Chemical & pharmaceutical bulletin 2009;57(11):1292-5.
2009: Seikou Nakamura; Junko Iwami; Hisashi Matsuda; Hiroko Wakayama; Yutana Pongpiriyadacha; Masayuki Yoshikawa
Structures of new phenylbutanoids and nitric oxide production inhibitors from the rhizomes of Zingiber cassumunar.
Chemical & pharmaceutical bulletin 2009;57(11):1267-72.
2009: Hisashi Matsuda; Kiyofumi Ninomiya; Toshio Morikawa; Daisuke Yasuda; Itadaki Yamaguchi; Masayuki Yoshikawa
Hepatoprotective amide constituents from the fruit of Piper chaba: Structural requirements, mode of action, and new amides.
Bioorganic & medicinal chemistry 2009;17(20):7313-23.
2009: fengming xu; Hisashi Matsuda; Hiroki Hata; Kaoru Sugawara; Seikou Nakamura; Masayuki Yoshikawa
Structures of new flavonoids and benzofuran-type stilbene and degranulation inhibitors of rat basophilic leukemia cells from the Brazilian herbal medicine Cissus sicyoides.
Chemical & pharmaceutical bulletin 2009;57(10):1089-95.
2009: Masayuki Yoshikawa; Toshio Morikawa; Hideo Oominami; Hisashi Matsuda
Absolute stereostructures of olibanumols A, B, C, H, I, and J from olibanum, gum-resin of Boswellia carterii, and inhibitors of nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages.
Chemical & pharmaceutical bulletin 2009;57(9):957-64.
2009: Hisashi Matsuda; Souichi Nakashima; Yoshimi Oda; Seikou Nakamura; Masayuki Yoshikawa
Melanogenesis inhibitors from the rhizomes of Alpinia officinarum in B16 melanoma cells.
Bioorganic & medicinal chemistry 2009;17(16):6048-53.
2009: Toshio Morikawa; Li-Bo Wang; Kiyofumi Ninomiya; Seikou Nakamura; Hisashi Matsuda; Osamu Muraoka; Li-Jun Wu; Masayuki Yoshikawa
Medicinal flowers. XXX. Eight new glycosides, everlastosides F-M, from the flowers of Helichrysum arenarium.
Chemical & pharmaceutical bulletin 2009;57(8):853-9.
2009: Toshio Morikawa; Yuanyuan Xie; Yasunobu Asao; Masaki Okamoto; Chihiro Yamashita; Osamu Muraoka; Hisashi Matsuda; Yutana Pongpiriyadacha; Dan Yuan; Masayuki Yoshikawa
Oleanane-type triterpene oligoglycosides with pancreatic lipase inhibitory activity from the pericarps of Sapindus rarak.
Phytochemistry 2009;70(9):1166-72.
2009: Masayuki Yoshikawa; Sachiko Sugimoto; Yasuyo Kato; Seikou Nakamura; Tao Wang; Chihiro Yamashita; Hisashi Matsuda
Acylated oleanane-type triterpene saponins with acceleration of gastrointestinal transit and inhibitory effect on pancreatic lipase from flower buds of chinese tea plant (Camellia sinensis).
Chemistry & biodiversity 2009;6(6):903-15.
2009: Hisashi Matsuda; Yasunobu Asao; Seikou Nakamura; Makoto Hamao; Sachiko Sugimoto; Masako Hongo; Yutana Pongpiriyadacha; Masayuki Yoshikawa
Antidiabetogenic constituents from the Thai traditional medicine Cotylelobium melanoxylon.
Chemical & pharmaceutical bulletin 2009;57(5):487-94.
2009: Hisashi Matsuda; Junji Akaki; Seikou Nakamura; Yoshie Okazaki; Hiroaki Kojima; Makoto Tamesada; Masayuki Yoshikawa
Apoptosis-inducing effects of sterols from the dried powder of cultured mycelium of Cordyceps sinensis.
Chemical & pharmaceutical bulletin 2009;57(4):411-4.
2009: zhang hailong; Hisashi Matsuda; Chihiro Yamashita; Seikou Nakamura; Masayuki Yoshikawa
Hydrangeic acid from the processed leaves of Hydrangea macrophylla var. thunbergii as a new type of anti-diabetic compound.
European journal of pharmacology 2009;606(1-3):255-61.
2009: Toshio Morikawa; Haihui Xie; Tao Wang; Hisashi Matsuda; Masayuki Yoshikawa
Acylated flavonol bisdesmosides, sinocrassosides A3-A7 and B3, with aminopeptidase N inhibitory activity from Sinocrassula indica.
Chemistry & biodiversity 2009;6(3):411-20.
2009: Sachiko Sugimoto; Seikou Nakamura; Hisashi Matsuda; Niichiro Kitagawa; Masayuki Yoshikawa
Chemical constituents from seeds of Panax ginseng: structure of new dammarane-type triterpene ketone, panaxadione, and hplc comparisons of seeds and flesh.
Chemical & pharmaceutical bulletin 2009;57(3):283-7.
2009: Sachiko Sugimoto; Guihua Chi; Yasuyo Kato; Seikou Nakamura; Hisashi Matsuda; Masayuki Yoshikawa
Medicinal Flowers. XXVI. structures of acylated oleanane-type triterpene oligoglycosides, yuchasaponins A, B, C, and D, from the flower buds of Camellia oleifera-gastroprotective, aldose reductase inhibitory, and radical scavenging effects-.
Chemical & pharmaceutical bulletin 2009;57(3):269-75.
2009: Sachiko Sugimoto; Seikou Nakamura; Sachiyo Yamamoto; Chihiro Yamashita; Yoshimi Oda; Hisashi Matsuda; Masayuki Yoshikawa
Brazilian natural medicines. III. structures of triterpene oligoglycosides and lipase inhibitors from mate, leaves of ilex paraguariensis.
Chemical & pharmaceutical bulletin 2009;57(3):257-61.
2009: Yasunobu Asao; Toshio Morikawa; Yuanyuan Xie; Masaki Okamoto; Makoto Hamao; Hisashi Matsuda; Osamu Muraoka; Dan Yuan; Masayuki Yoshikawa
Structures of acetylated oleanane-type triterpene saponins, rarasaponins IV, V, and VI, and anti-hyperlipidemic constituents from the pericarps of Sapindus rarak.
Chemical & pharmaceutical bulletin 2009;57(2):198-203.
2009: Hisashi Matsuda; Sachie Kiyohara; Sachiko Sugimoto; Shin Ando; Seikou Nakamura; Masayuki Yoshikawa
Bioactive constituents from Chinese natural medicines. XXXIII. Inhibitors from the seeds of Psoralea corylifolia on production of nitric oxide in lipopolysaccharide-activated macrophages.
Biological & pharmaceutical bulletin 2009;32(1):147-9.
2009: Yang Qu; fengming xu; Seikou Nakamura; Hisashi Matsuda; Yutana Pongpiriyadacha; Lijun Wu; Masayuki Yoshikawa
Sesquiterpenes from Curcuma comosa.
Journal of natural medicines 2009;63(1):102-4.
2008: fengming xu; Seikou Nakamura; Yang Qu; Hisashi Matsuda; Yutana Pongpiriyadacha; Lijun Wu; Masayuki Yoshikawa
Structures of new sesquiterpenes from Curcuma comosa.
Chemical & pharmaceutical bulletin 2008;56(12):1710-6.
2008: Seikou Nakamura; Yoshie Okazaki; Kiyofumi Ninomiya; Toshio Morikawa; Hisashi Matsuda; Masayuki Yoshikawa
Medicinal flowers. XXIV. Chemical structures and hepatoprotective effects of constituents from flowers of Hedychium coronarium.
Chemical & pharmaceutical bulletin 2008;56(12):1704-9.
2008: Seikou Nakamura; Yang Qu; fengming xu; Hisashi Matsuda; Masayuki Yoshikawa
Structures of new monoterpenes from Thai herbal medicine Curcuma comosa.
Chemical & pharmaceutical bulletin 2008;56(11):1604-6.
2008: Toshio Morikawa; Haihui Xie; Tao Wang; Hisashi Matsuda; Masayuki Yoshikawa
Bioactive constituents from Chinese natural medicines. XXXII. aminopeptidase N and aldose reductase inhibitors from Sinocrassula indica: structures of sinocrassosides B(4), B(5), C(1), and D(1)-D(3).
Chemical & pharmaceutical bulletin 2008;56(10):1438-44.
2008: Masayuki Yoshikawa; Sachiko Sugimoto; Seikou Nakamura; Hisashi Matsuda
Medicinal flowers. XXII. Structures of chakasaponins V and VI, chakanoside I, and chakaflavonoside A from flower buds of Chinese tea plant (Camellia sinensis).
Chemical & pharmaceutical bulletin 2008;56(9):1297-303.
2008: Ai Kurume; Yasuhiro Kamata; Masayuki Yamashita; Qilong Wang; Hisashi Matsuda; Masayuki Yoshikawa; Ikuo Kawasaki; Shunsaku Ohta
Synthesis of 3-substituted isocoumarins and their inhibitory effects on degranulation of RBL-2H3 cells induced by antigen.
Chemical & pharmaceutical bulletin 2008;56(9):1264-9.
2008: Masayuki Yoshikawa; Yi Zhang; Tao Wang; Seikou Nakamura; Hisashi Matsuda
New triterpene constituents, foliasalacins A(1)-A(4), B(1)-B(3), and C, from the leaves of Salacia chinensis.
Chemical & pharmaceutical bulletin 2008;56(7):915-20.
2008: zhang hailong; Hisashi Matsuda; Seikou Nakamura; Masayuki Yoshikawa
Effects of amide constituents from pepper on adipogenesis in 3T3-L1 cells.
Bioorganic & medicinal chemistry letters 2008;18(11):3272-7.
2008: Masayuki Yoshikawa; Seikou Nakamura; Xuezheng Li; Hisashi Matsuda
Reinvestigation of absolute stereostructure of (-)-rosiridol: structures of monoterpene glycosides, rosiridin, rosiridosides A, B, and C, from Rhodiola sachalinensis.
Chemical & pharmaceutical bulletin 2008;56(5):695-700.
2008: Seikou Nakamura; Masako Hongo; Sachiko Sugimoto; Hisashi Matsuda; Masayuki Yoshikawa
Steroidal saponins and pseudoalkaloid oligoglycoside from Brazilian natural medicine, "fruta do lobo" (fruit of Solanum lycocarpum).
Phytochemistry 2008;69(7):1565-72.
2008: Xuezheng Li; Seikou Nakamura; Hisashi Matsuda; Masayuki Yoshikawa
Bioactive constituents from chinese natural medicines. XXIX. Monoterpene and monoterpene glycosides from the roots of Rhodiola sachalinensis.
Chemical & pharmaceutical bulletin 2008;56(4):612-5.
2008: Masayuki Yoshikawa; Xuezheng Li; Eriko Nishida; Seikou Nakamura; Hisashi Matsuda; Osamu Muraoka; Toshio Morikawa
Medicinal flowers. XXI. Structures of perennisaponins A, B, C, D, E, and F, acylated oleanane-type triterpene oligoglycosides, from the flowers of Bellis perennis.
Chemical & pharmaceutical bulletin 2008;56(4):559-68.
2008: Yi Zhang; Seikou Nakamura; Yutana Pongpiriyadacha; Hisashi Matsuda; Masayuki Yoshikawa
Absolute structures of new megastigmane glycosides, foliasalaciosides E(1), E(2), E(3), F, G, H, and I from the leaves of Salacia chinensis.
Chemical & pharmaceutical bulletin 2008;56(4):547-53.
2008: Seikou Nakamura; Xuezheng Li; Hisashi Matsuda; Masayuki Yoshikawa
Bioactive constituents from Chinese natural medicines. XXVIII. Chemical structures of acyclic alcohol glycosides from the roots of Rhodiola crenulata.
Chemical & pharmaceutical bulletin 2008;56(4):536-40.
2008: Hisashi Matsuda; Kiyofumi Ninomiya; Toshio Morikawa; Daisuke Yasuda; Itadaki Yamaguchi; Masayuki Yoshikawa
Protective effects of amide constituents from the fruit of Piper chaba on D-galactosamine/TNF-alpha-induced cell death in mouse hepatocytes.
Bioorganic & medicinal chemistry letters 2008;18(6):2038-42.
2008: Hisashi Matsuda; Qilong Wang; Koudai Matsuhira; Seikou Nakamura; Dan Yuan; Masayuki Yoshikawa
Inhibitory effects of thunberginols A and B isolated from Hydrangeae Dulcis Folium on mRNA expression of cytokines and on activation of activator protein-1 in RBL-2H3 cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2008;15(3):177-84.
2007: Seikou Nakamura; Sachiko Sugimoto; Hisashi Matsuda; Masayuki Yoshikawa
Medicinal flowers. XVII. New dammarane-type triterpene glycosides from flower buds of American ginseng, Panax quinquefolium L.
Chemical & pharmaceutical bulletin 2007;55(9):1342-8.
2007: Masayuki Yoshikawa; Tao Wang; Toshio Morikawa; Haihui Xie; Hisashi Matsuda
Bioactive constituents from chinese natural medicines. XXIV. Hypoglycemic effects of Sinocrassula indica in sugar-loaded rats and genetically diabetic KK-A(y) mice and structures of new acylated flavonol glycosides, sinocrassosides A(1), A(2), B(1), and B(2).
Chemical & pharmaceutical bulletin 2007;55(9):1308-15.
2007: zhang hailong; Hisashi Matsuda; Akira Kumahara; Yuki Ito; Seikou Nakamura; Masayuki Yoshikawa
New type of anti-diabetic compounds from the processed leaves of Hydrangea macrophylla var. thunbergii (Hydrangeae Dulcis Folium).
Bioorganic & medicinal chemistry letters 2007;17(17):4972-6.
2007: Masayuki Yoshikawa; Sachiko Sugimoto; Seikou Nakamura; Hayaka Sakumae; Hisashi Matsuda
Medicinal flowers. XVI. New dammarane-type triterpene tetraglycosides and gastroprotective principles from flower buds of Panax ginseng.
Chemical & pharmaceutical bulletin 2007;55(7):1034-8.
2007: Genzoh Tanabe; Kazuya Yoshikai; Takanori Hatanaka; Mizuho Yamamoto; Ying Shao; Toshie Minematsu; Osamu Muraoka; Tao Wang; Hisashi Matsuda; Masayuki Yoshikawa
Biological evaluation of de-O-sulfonated analogs of salacinol, the role of sulfate anion in the side chain on the alpha-glucosidase inhibitory activity.
Bioorganic & medicinal chemistry 2007;15(11):3926-37.
2007: Kiyofumi Ninomiya; Hisashi Matsuda; Mizuho Kubo; Toshio Morikawa; Norihisa Nishida; Masayuki Yoshikawa
Potent anti-obese principle from Rosa canina: structural requirements and mode of action of trans-tiliroside.
Bioorganic & medicinal chemistry letters 2007;17(11):3059-64.
2007: Masayuki Yoshikawa; Toshio Morikawa; Yasunobu Asao; Emi Fujiwara; Seikou Nakamura; Hisashi Matsuda
Medicinal flowers. XV. The structures of noroleanane- and oleanane-type triterpene oligoglycosides with gastroprotective and platelet aggregation activities from flower buds of Camellia japonica.
Chemical & pharmaceutical bulletin 2007;55(4):606-12.
2007: Masayuki Yoshikawa; Seikou Nakamura; Yasuyo Kato; Koudai Matsuhira; Hisashi Matsuda
Medicinal flowers. XIV. New acylated oleanane-type triterpene oligoglycosides with antiallergic activity from flower buds of chinese tea plant (Camellia sinensis).
Chemical & pharmaceutical bulletin 2007;55(4):598-605.
2007: Masayuki Yoshikawa; Toshio Morikawa; Yi Zhang; Seikou Nakamura; Osamu Muraoka; Hisashi Matsuda
Megastigmanes and their glucosides from the whole plant of Sedum sarmentosum.
Journal of natural products 2007;70(4):575-83.
2007: Toshio Morikawa; Yi Zhang; Seikou Nakamura; Hisashi Matsuda; Osamu Muraoka; Masayuki Yoshikawa
Bioactive constituents from Chinese natural medicines. XXII. Absolute structures of new megastigmane glycosides, sedumosides E1, E2, E3, F1, F2, and G, from Sedum sarmentosum (Crassulaceae).
Chemical & pharmaceutical bulletin 2007;55(3):435-41.
2007: Masayuki Yoshikawa; Toshio Morikawa; Hisanori Kobayashi; Akihiko Nakamura; Koudai Matsuhira; Seikou Nakamura; Hisashi Matsuda
Bioactive saponins and glycosides. XXVII. Structures of new cucurbitane-type triterpene glycosides and antiallergic constituents from Citrullus colocynthis.
Chemical & pharmaceutical bulletin 2007;55(3):428-34.
2007: Masayuki Yoshikawa; fengming xu; Toshio Morikawa; Yutana Pongpiriyadacha; Seikou Nakamura; Yasunobu Asao; Akira Kumahara; Hisashi Matsuda
Medicinal flowers. XII.(1)) New spirostane-type steroid saponins with antidiabetogenic activity from Borassus flabellifer.
Chemical & pharmaceutical bulletin 2007;55(2):308-16.
2007: Toshio Morikawa; Seikou Nakamura; Yasuyo Kato; Osamu Muraoka; Hisashi Matsuda; Masayuki Yoshikawa
Bioactive saponins and glycosides. XXVIII. New triterpene saponins, foliatheasaponins I, II, III, IV, and V, from Tencha (the leaves of Camellia sinensis).
Chemical & pharmaceutical bulletin 2007;55(2):293-8.
2007: Qilong Wang; Hisashi Matsuda; Koudai Matsuhira; Seikou Nakamura; Dan Yuan; Masayuki Yoshikawa
Inhibitory effects of thunberginols A, B, and F on degranulations and releases of TNF-alpha and IL-4 in RBL-2H3 cells.
Biological & pharmaceutical bulletin 2007;30(2):388-92.
2007: Masayuki Yoshikawa; Seikou Nakamura; Kenichi Ozaki; Akira Kumahara; Toshio Morikawa; Hisashi Matsuda
Structures of steroidal alkaloid oligoglycosides, robeneosides A and B, and antidiabetogenic constituents from the Brazilian medicinal plant Solanum lycocarpum.
Journal of natural products 2007;70(2):210-4.
2007: Hisashi Matsuda; Kazutoshi Yoshida; Katsutoshi Miyagawa; Yasunobu Asao; Saya Takayama; Souichi Nakashima; fengming xu; Masayuki Yoshikawa
Rotenoids and flavonoids with anti-invasion of HT1080, anti-proliferation of U937, and differentiation-inducing activity in HL-60 from Erycibe expansa.
Bioorganic & medicinal chemistry 2007;15(3):1539-46.
2007: Hisashi Matsuda; Sachiko Sugimoto; Toshio Morikawa; Koudai Matsuhira; Eri Mizuguchi; Seikou Nakamura; Masayuki Yoshikawa
Bioactive constituents from Chinese natural medicines. XX. Inhibitors of antigen-induced degranulation in RBL-2H3 cells from the seeds of Psoralea corylifolia.
Chemical & pharmaceutical bulletin 2007;55(1):106-10.
2007: Masayuki Yoshikawa; Toshio Morikawa; Seikou Nakamura; Ning Li; Xian Li; Hisashi Matsuda
Bioactive saponins and glycosides. XXV. Acylated oleanane-type triterpene saponins from the seeds of tea plant (Camellia sinensis).
Chemical & pharmaceutical bulletin 2007;55(1):57-63.
2006: Masayuki Yoshikawa; Hisashi Matsuda; Toshio Morikawa; Haihui Xie; Seikou Nakamura; Osamu Muraoka
Phenylethanoid oligoglycosides and acylated oligosugars with vasorelaxant activity from Cistanche tubulosa.
Bioorganic & medicinal chemistry 2006;14(22):7468-75.
2006: Seikou Nakamura; Toshiyuki Murakami; Junko Nakamura; Hisanori Kobayashi; Hisashi Matsuda; Masayuki Yoshikawa
Structures of new cucurbitane-type triterpenes and glycosides, karavilagenins and karavilosides, from the dried fruit of Momordica charantia L. in Sri Lanka.
Chemical & pharmaceutical bulletin 2006;54(11):1545-50.
2006: Toshio Morikawa; fengming xu; Hisashi Matsuda; Masayuki Yoshikawa
Structures of new flavonoids, erycibenins D, E, and F, and NO production inhibitors from Erycibe expansa originating in Thailand.
Chemical & pharmaceutical bulletin 2006;54(11):1530-4.
2006: Toshio Morikawa; Haihui Xie; Hisashi Matsuda; Masayuki Yoshikawa
Glucosyloxybenzyl 2-Isobutylmalates from the tubers of Gymnadenia conopsea.
Journal of natural products 2006;69(6):881-6.
2006: Haihui Xie; Toshio Morikawa; Hisashi Matsuda; Seikou Nakamura; Osamu Muraoka; Masayuki Yoshikawa
Monoterpene constituents from Cistanche tubulosa--chemical structures of kankanosides A-E and kankanol-.
Chemical & pharmaceutical bulletin 2006;54(5):669-75.
2006: Hiroshi Shimoda; Junji Tanaka; Emi Yamada; Toshio Morikawa; Naoki Kasajima; Masayuki Yoshikawa
Anti type I allergic property of Japanese butterbur extract and its mast cell degranulation inhibitory ingredients.
Journal of agricultural and food chemistry 2006;54(8):2915-20.
2006: Toshio Morikawa; Haihui Xie; Hisashi Matsuda; Tao Wang; Masayuki Yoshikawa
Bioactive constituents from Chinese natural medicines. XVII. constituents with radical scavenging effect and new glucosyloxybenzyl 2-isobutylmalates from Gymnadenia conopsea.
Chemical & pharmaceutical bulletin 2006;54(4):506-13.
2006: Hisashi Matsuda; Kazutoshi Yoshida; Katsutoshi Miyagawa; Yumiko Nemoto; Yasunobu Asao; Masayuki Yoshikawa
Nuphar alkaloids with immediately apoptosis-inducing activity from Nuphar pumilum and their structural requirements for the activity.
Bioorganic & medicinal chemistry letters 2006;16(6):1567-73.
2006: Toshio Morikawa; Ning Li; Akifumi Nagatomo; Hisashi Matsuda; Xian Li; Masayuki Yoshikawa
Triterpene saponins with gastroprotective effects from tea seed (the seeds of Camellia sinensis).
Journal of natural products 2006;69(2):185-90.
2006: Masayuki Yoshikawa; Norihisa Nishida; Kiyofumi Ninomiya; Teruki Ohgushi; Mizuho Kubo; Toshio Morikawa; Hisashi Matsuda
Inhibitory effects of coumarin and acetylene constituents from the roots of Angelica furcijuga on D-galactosamine/lipopolysaccharide-induced liver injury in mice and on nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages.
Bioorganic & medicinal chemistry 2006;14(2):456-63.
2006: Osamu Muraoka; Kazuya Yoshikai; Hideo Takahashi; Toshie Minematsu; Guangxin Lu; Genzoh Tanabe; Tao Wang; Hisashi Matsuda; Masayuki Yoshikawa
Synthesis and biological evaluation of deoxy salacinols, the role of polar substituents in the side chain on the alpha-glucosidase inhibitory activity.
Bioorganic & medicinal chemistry 2006;14(2):500-9.
2006: Hisashi Matsuda; Shin Ando; Tomoko Kato; Toshio Morikawa; Masayuki Yoshikawa
Inhibitors from the rhizomes of Alpinia officinarum on production of nitric oxide in lipopolysaccharide-activated macrophages and the structural requirements of diarylheptanoids for the activity.
Bioorganic & medicinal chemistry 2006;14(1):138-42.
2005: Masayuki Yoshikawa; Toshio Morikawa; Ning Li; Akifumi Nagatomo; Xian Li; Hisashi Matsuda
Bioactive saponins and glycosides. XXIII. Triterpene saponins with gastroprotective effect from the seeds of Camellia sinensis--theasaponins E3, E4, E5, E6, and E7.
Chemical & pharmaceutical bulletin 2005;53(12):1559-64.
2005: Haihui Xie; Tao Wang; Hisashi Matsuda; Toshio Morikawa; Masayuki Yoshikawa; Tadato Tani
Bioactive constituents from Chinese natural medicines. XV. Inhibitory effect on aldose reductase and structures of Saussureosides A and B from Saussurea medusa.
Chemical & pharmaceutical bulletin 2005;53(11):1416-22.
2005: Masayuki Yoshikawa; Toshio Morikawa; Kaori Yamamoto; Yasuyo Kato; Akifumi Nagatomo; Hisashi Matsuda
Floratheasaponins A-C, acylated oleanane-type triterpene oligoglycosides with anti-hyperlipidemic activities from flowers of the tea plant (Camellia sinensis).
Journal of natural products 2005;68(9):1360-5.
2005: Toshio Morikawa; Shin Ando; Hisashi Matsuda; Shinya Kataoka; Osamu Muraoka; Masayuki Yoshikawa
Inhibitors of nitric oxide production from the rhizomes of Alpinia galanga: structures of new 8-9' linked neolignans and sesquineolignan.
Chemical & pharmaceutical bulletin 2005;53(6):625-30.
2005: Shin Ando; Hisashi Matsuda; Toshio Morikawa; Masayuki Yoshikawa
1'S-1'-Acetoxychavicol acetate as a new type inhibitor of interferon-beta production in lipopolysaccharide-activated mouse peritoneal macrophages.
Bioorganic & medicinal chemistry 2005;13(9):3289-94.
2005: Hisashi Matsuda; Shin Ando; Toshio Morikawa; Shinya Kataoka; Masayuki Yoshikawa
Structure-activity relationships of 1'S-1'-acetoxychavicol acetate for inhibitory effect on NO production in lipopolysaccharide-activated mouse peritoneal macrophages.
Bioorganic & medicinal chemistry letters 2005;15(7):1949-53.
2004: Hisashi Matsuda; Supinya Tewtrakul; Toshio Morikawa; Akihiko Nakamura; Masayuki Yoshikawa
Anti-allergic principles from Thai zedoary: structural requirements of curcuminoids for inhibition of degranulation and effect on the release of TNF-alpha and IL-4 in RBL-2H3 cells.
Bioorganic & medicinal chemistry 2004;12(22):5891-8.
2004: Toshio Morikawa; Hisashi Matsuda; Norihisa Nishida; Teruki Ohgushi; Masayuki Yoshikawa
Structures of new aromatics glycosides from a Japanese folk medicine, the roots of Angelica furcijuga.
Chemical & pharmaceutical bulletin 2004;52(11):1387-90.
2004: Hisashi Matsuda; Supinya Tewtrakul; Toshio Morikawa; Masayuki Yoshikawa
Anti-allergic activity of stilbenes from Korean rhubarb (Rheum undulatum L.): structure requirements for inhibition of antigen-induced degranulation and their effects on the release of TNF-alpha and IL-4 in RBL-2H3 cells.
Bioorganic & medicinal chemistry 2004;12(18):4871-6.
2004: Bohang Sun; Toshio Morikawa; Hisashi Matsuda; Supinya Tewtrakul; Li Jun Wu; Shoichi Harima; Masayuki Yoshikawa
Structures of new beta-carboline-type alkaloids with antiallergic effects from Stellaria dichotoma(1,2).
Journal of natural products 2004;67(9):1464-9.
2004: Hisashi Matsuda; Toshio Morikawa; Haihui Xie; Masayuki Yoshikawa
Antiallergic phenanthrenes and stilbenes from the tubers of Gymnadenia conopsea.
Planta medica 2004;70(9):847-55.
2004: Hisashi Matsuda; Toshio Morikawa; Shin Ando; Hideo Oominami; Toshiyuki Murakami; Ikuko Kimura; Masayuki Yoshikawa
Absolute stereostructures of polypodane- and octanordammarane-type triterpenes with nitric oxide production inhibitory activity from guggul-gum resins.
Bioorganic & medicinal chemistry 2004;12(11):3037-46.
2004: Kiyofumi Ninomiya; Hisashi Matsuda; Hiroshi Shimoda; Norihisa Nishida; Naoki Kasajima; Tomoe Yoshino; Toshio Morikawa; Masayuki Yoshikawa
Carnosic acid, a new class of lipid absorption inhibitor from sage.
Bioorganic & medicinal chemistry letters 2004;14(8):1943-6.
2004: fengming xu; Toshio Morikawa; Hisashi Matsuda; Kiyofumi Ninomiya; Masayuki Yoshikawa
Structures of new sesquiterpenes and hepatoprotective constituents from the Egyptian herbal medicine Cyperus longus.
Journal of natural products 2004;67(4):569-76.
2004: Toshio Morikawa; fengming xu; Kiyofumi Ninomiya; Hisashi Matsuda; Masayuki Yoshikawa
Nigellamines A3, A4, A5, and C, new dolabellane-type diterpene alkaloids, with lipid metabolism-promoting activities from the Egyptian medicinal food black cumin.
Chemical & pharmaceutical bulletin 2004;52(4):494-7.
2004: Toshio Morikawa; fengming xu; Yousuke Kashima; Hisashi Matsuda; Kiyofumi Ninomiya; Masayuki Yoshikawa
Novel dolabellane-type diterpene alkaloids with lipid metabolism promoting activities from the seeds of Nigella sativa.
Organic letters 2004;6(6):869-72.
2004: Toshio Morikawa; Hisashi Matsuda; Itadaki Yamaguchi; Yutana Pongpiriyadacha; Masayuki Yoshikawa
New amides and gastroprotective constituents from the fruit of Piper chaba.
Planta medica 2004;70(2):152-9.
2003: Hisashi Matsuda; Toshio Morikawa; Mamiko Oda; Yasunobu Asao; Masayuki Yoshikawa
Potent anti-metastatic activity of dimeric sesquiterpene thioalkaloids from the rhizome of Nuphar pumilum.
Bioorganic & medicinal chemistry letters 2003;13(24):4445-9.
2003: Hisashi Matsuda; Tao Wang; Hiromi Managi; Masayuki Yoshikawa
Structural requirements of flavonoids for inhibition of protein glycation and radical scavenging activities.
Bioorganic & medicinal chemistry 2003;11(24):5317-23.
2003: Hisashi Matsuda; Toshio Morikawa; Hiromi Managi; Masayuki Yoshikawa
Antiallergic principles from Alpinia galanga: structural requirements of phenylpropanoids for inhibition of degranulation and release of TNF-alpha and IL-4 in RBL-2H3 cells.
Bioorganic & medicinal chemistry letters 2003;13(19):3197-202.
2003: Masayuki Yoshikawa; Yutana Pongpiriyadacha; Akinobu Kishi; Tadashi Kageura; Tao Wang; Toshio Morikawa; Hisashi Matsuda
[Biological activities of Salacia chinensis originating in Thailand: the quality evaluation guided by alpha-glucosidase inhibitory activity].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2003;123(10):871-80.
2003: Toshio Morikawa; Akinobu Kishi; Yutana Pongpiriyadacha; Hisashi Matsuda; Masayuki Yoshikawa
Structures of new friedelane-type triterpenes and eudesmane-type sesquiterpene and aldose reductase inhibitors from Salacia chinensis.
Journal of natural products 2003;66(9):1191-6.
2003: Akinobu Kishi; Toshio Morikawa; Hisashi Matsuda; Masayuki Yoshikawa
Structures of new friedelane- and norfriedelane-type triterpenes and polyacylated eudesmane-type sesquiterpene from Salacia chinensis LINN. (S. prinoides DC., Hippocrateaceae) and radical scavenging activities of principal constituents.
Chemical & pharmaceutical bulletin 2003;51(9):1051-5.
2003: Masayuki Yoshikawa; Toshio Morikawa; Yousuke Kashima; Kiyofumi Ninomiya; Hisashi Matsuda
Structures of new dammarane-type Triterpene Saponins from the flower buds of Panax notoginseng and hepatoprotective effects of principal Ginseng Saponins.
Journal of natural products 2003;66(7):922-7.
2003: Hisashi Matsuda; Yutana Pongpiriyadacha; Toshio Morikawa; Momotaro Ochi; Masayuki Yoshikawa
Gastroprotective effects of phenylpropanoids from the rhizomes of Alpinia galanga in rats: structural requirements and mode of action.
European journal of pharmacology 2003;471(1):59-67.
2003: Toshio Morikawa; Jing Tao; Shin Ando; Hisashi Matsuda; Masayuki Yoshikawa
Absolute stereostructures of new arborinane-type triterpenoids and inhibitors of nitric oxide production from Rubia yunnanensis.
Journal of natural products 2003;66(5):638-45.
2003: Yutana Pongpiriyadacha; Hisashi Matsuda; Toshio Morikawa; Yasunobu Asao; Masayuki Yoshikawa
Protective effects of polygodial on gastric mucosal lesions induced by necrotizing agents in rats and the possible mechanisms of action.
Biological & pharmaceutical bulletin 2003;26(5):651-7.
2003: Hisashi Matsuda; Toshio Morikawa; Shin Ando; Iwao Toguchida; Masayuki Yoshikawa
Structural requirements of flavonoids for nitric oxide production inhibitory activity and mechanism of action.
Bioorganic & medicinal chemistry 2003;11(9):1995-2000.
2003: Hisashi Matsuda; Toshio Morikawa; Tomoko Ishiwada; Hiromi Managi; Masatomo Kagawa; Yoshihiko Higashi; Masayuki Yoshikawa
Medicinal flowers. VIII. Radical scavenging constituents from the flowers of Prunus mume: structure of prunose III.
Chemical & pharmaceutical bulletin 2003;51(4):440-3.
2003: Hisashi Matsuda; Yutana Pongpiriyadacha; Toshio Morikawa; Akinobu Kishi; Shinya Kataoka; Masayuki Yoshikawa
Protective effects of steroid saponins from Paris polyphylla var. yunnanensis on ethanol- or indomethacin-induced gastric mucosal lesions in rats: structural requirement for activity and mode of action.
Bioorganic & medicinal chemistry letters 2003;13(6):1101-6.
2003: Masayuki Yoshikawa; fengming xu; Toshio Morikawa; Kiyofumi Ninomiya; Hisashi Matsuda
Anastatins A and B, new skeletal flavonoids with hepatoprotective activities from the desert plant Anastatica hierochuntica.
Bioorganic & medicinal chemistry letters 2003;13(6):1045-9.
2003: Hisashi Matsuda; Iwao Toguchida; Kiyofumi Ninomiya; Tadashi Kageura; Toshio Morikawa; Masayuki Yoshikawa
Effects of sesquiterpenes and amino acid-sesquiterpene conjugates from the roots of Saussurea lappa on inducible nitric oxide synthase and heat shock protein in lipopolysaccharide-activated macrophages.
Bioorganic & medicinal chemistry 2003;11(5):709-15.
2003: Hiroshi Shimoda; Kiyofumi Ninomiya; Norihisa Nishida; Tomoe Yoshino; Toshio Morikawa; Hisashi Matsuda; Masayuki Yoshikawa
Anti-hyperlipidemic sesquiterpenes and new sesquiterpene glycosides from the leaves of artichoke (Cynara scolymus L.): structure requirement and mode of action.
Bioorganic & medicinal chemistry letters 2003;13(2):223-8.
2003: Toshio Morikawa; Jing Tao; Iwao Toguchida; Hisashi Matsuda; Masayuki Yoshikawa
Structures of new cyclic diarylheptanoids and inhibitors of nitric oxide production from Japanese folk medicine Acer nikoense.
Journal of natural products 2003;66(1):86-91.
2002: Jing Tao; Toshio Morikawa; Iwao Toguchida; Shin Ando; Hisashi Matsuda; Masayuki Yoshikawa
Inhibitors of nitric oxide production from the bark of Myrica rubra: structures of new biphenyl type diarylheptanoid glycosides and taraxerane type triterpene.
Bioorganic & medicinal chemistry 2002;10(12):4005-12.
2002: Masayuki Yoshikawa; Toshio Morikawa; Kyoko Nakano; Yutana Pongpiriyadacha; Toshiyuki Murakami; Hisashi Matsuda
Characterization of new sweet triterpene saponins from Albizia myriophylla.
Journal of natural products 2002;65(11):1638-42.
2002: Toshio Morikawa; Hisashi Matsuda; Iwao Toguchida; Kazuho Ueda; Masayuki Yoshikawa
Absolute stereostructures of three new sesquiterpenes from the fruit of Alpinia oxyphylla with inhibitory effects on nitric oxide production and degranulation in RBL-2H3 cells.
Journal of natural products 2002;65(10):1468-74.
2002: Hisashi Mastuda; Toshio Morikawa; Kazuho Ueda; Hiromi Managi; Masayuki Yoshikawa
Structural requirements of flavonoids for inhibition of antigen-Induced degranulation, TNF-alpha and IL-4 production from RBL-2H3 cells.
Bioorganic & medicinal chemistry 2002;10(10):3123-8.
2002: Masayuki Yoshikawa; Toshiyuki Murakami; Tomoko Ishiwada; Toshio Morikawa; Masatomo Kagawa; Yoshihiko Higashi; Hisashi Matsuda
New flavonol oligoglycosides and polyacylated sucroses with inhibitory effects on aldose reductase and platelet aggregation from the flowers of Prunus mume.
Journal of natural products 2002;65(8):1151-5.
2002: Hisashi Matsuda; Toshio Morikawa; Iwao Toguchida; Shoichi Harima; Masayuki Yoshikawa
Medicinal flowers. VI. Absolute stereostructures of two new flavanone glycosides and a phenylbutanoid glycoside from the flowers of Chrysanthemum indicum L.: their inhibitory activities for rat lens aldose reductase.
Chemical & pharmaceutical bulletin 2002;50(7):972-5.
2002: Masayuki Yoshikawa; Hiroshi Shimoda; Norihisa Nishida; Miki Takada; Hisashi Matsuda
Salacia reticulata and its polyphenolic constituents with lipase inhibitory and lipolytic activities have mild antiobesity effects in rats.
The Journal of nutrition 2002;132(7):1819-24.
2002: Hisashi Matsuda; Toshio Morikawa; Iwao Toguchida; Masayuki Yoshikawa
Structural requirements of flavonoids and related compounds for aldose reductase inhibitory activity.
Chemical & pharmaceutical bulletin 2002;50(6):788-95.
2002: Toshio Morikawa; Hisashi Matsuda; Kiyofumi Ninomiya; Masayuki Yoshikawa
Medicinal foodstuffs. XXIX. Potent protective effects of sesquiterpenes and curcumin from Zedoariae Rhizoma on liver injury induced by D-galactosamine/lipopolysaccharide or tumor necrosis factor-alpha.
Biological & pharmaceutical bulletin 2002;25(5):627-31.
2002: Masayuki Yoshikawa; Toshio Morikawa; Hisashi Matsuda; Genzoh Tanabe; Osamu Muraoka
Absolute stereostructure of potent alpha-glucosidase inhibitor, Salacinol, with unique thiosugar sulfonium sulfate inner salt structure from Salacia reticulata.
Bioorganic & medicinal chemistry 2002;10(5):1547-54.
2002: Hisashi Matsuda; Hiroshi Shimoda; Kiyofumi Ninomiya; Masayuki Yoshikawa
Inhibitory mechanism of costunolide, a sesquiterpene lactone isolated from Laurus nobilis, on blood-ethanol elevation in rats: involvement of inhibition of gastric emptying and increase in gastric juice secretion.
Alcohol and alcoholism (Oxford, Oxfordshire) 2002;37(2):121-7.
2002: Hisashi Matsuda; Norihisa Nishida; Masayuki Yoshikawa
Antidiabetic principles of natural medicines. V. Aldose reductase inhibitors from Myrcia multiflora DC. (2): Structures of myrciacitrins III, IV, and V.
Chemical & pharmaceutical bulletin 2002;50(3):429-31.
2002: Hisashi Matsuda; Kiyofumi Ninomiya; Hiroshi Shimoda; Masayuki Yoshikawa
Hepatoprotective principles from the flowers of Tilia argentea (linden): structure requirements of tiliroside and mechanisms of action.
Bioorganic & medicinal chemistry 2002;10(3):707-12.
2002: Hisashi Matsuda; Yutana Pongpiriyadacha; Toshio Morikawa; Yousuke Kashima; Kyoko Nakano; Masayuki Yoshikawa
Protective effects of polygodial and related compounds on ethanol-induced gastric mucosal lesions in rats: structural requirements and mode of action.
Bioorganic & medicinal chemistry letters 2002;12(3):477-82.
2002: Hisashi Matsuda; Toshio Morikawa; Jing Tao; Kazuho Ueda; Masayuki Yoshikawa
Bioactive constituents of Chinese natural medicines. VII. Inhibitors of degranulation in RBL-2H3 cells and absolute stereostructures of three new diarylheptanoid glycosides from the bark of Myrica rubra.
Chemical & pharmaceutical bulletin 2002;50(2):208-15.
2002: Masayuki Yoshikawa; Kiyofumi Ninomiya; Hiroshi Shimoda; Norihisa Nishida; Hisashi Matsuda
Hepatoprotective and antioxidative properties of Salacia reticulata: preventive effects of phenolic constituents on CCl4-induced liver injury in mice.
Biological & pharmaceutical bulletin 2002;25(1):72-6.
2001: Hisashi Matsuda; Toshio Morikawa; Iwao Toguchida; Kiyofumi Ninomiya; Masayuki Yoshikawa
Medicinal foodstuffs. XXVIII. Inhibitors of nitric oxide production and new sesquiterpenes, zedoarofuran, 4-epicurcumenol, neocurcumenol, gajutsulactones A and B, and zedoarolides A and B, from Zedoariae Rhizoma.
Chemical & pharmaceutical bulletin 2001;49(12):1558-66.
2001: Osamu Muraoka; S Ying; Kazuya Yoshikai; Y Matsuura; E Yamada; Toshie Minematsu; Genzoh Tanabe; Hisashi Matsuda; Masayuki Yoshikawa
Synthesis of a nitrogen analogue of salacinol and its alpha-glucosidase inhibitory activity.
Chemical & pharmaceutical bulletin 2001;49(11):1503-5.
2001: Masayuki Yoshikawa; Toshio Morikawa; K Yashiro; Toshiyuki Murakami; Hisashi Matsuda
Bioactive saponins and glycosides. XIX. Notoginseng (3): immunological adjuvant activity of notoginsenosides and related saponins: structures of notoginsenosides-L, -M, and -N from the roots of Panax notoginseng (Burk.) F. H. Chen.
Chemical & pharmaceutical bulletin 2001;49(11):1452-6.
2001: Hisashi Matsuda; Toshio Morikawa; H Ueda; Masayuki Yoshikawa
Medicinal foodstuffs. XXVII. Saponin constituents of gotu kola (2): structures of new ursane- and oleanane-type triterpene oligoglycosides, centellasaponins B, C, and D, from Centella asiatica cultivated in Sri Lanka.
Chemical & pharmaceutical bulletin 2001;49(10):1368-71.
2001: Osamu Muraoka; M Fujimoto; Genzoh Tanabe; M Kubo; Toshie Minematsu; Hisashi Matsuda; Toshio Morikawa; I Toguchida; Masayuki Yoshikawa
Absolute stereostructures of novel norcadinane- and trinoreudesmane-type sesquiterpenes with nitric oxide production inhibitory activity from Alpinia oxyphylla.
Bioorganic & medicinal chemistry letters 2001;11(16):2217-20.
2001: T Marukami; Akinobu Kishi; Masayuki Yoshikawa
Medicinal flowers. IV. Marigold. (2): Structures of new ionone and sesquiterpene glycosides from Egyptian Calendula officinalis.
Chemical & pharmaceutical bulletin 2001;49(8):974-8.
2001: Toshiyuki Murakami; K Kohno; Kiyofumi Ninomiya; Hisashi Matsuda; Masayuki Yoshikawa
Medicinal foodstuffs. XXV. Hepatoprotective principle and structures of ionone glucoside, phenethyl glycoside, and flavonol oligoglycosides from young seedpods of garden peas, Pisum sativum L.
Chemical & pharmaceutical bulletin 2001;49(8):1003-8.
2001: Hisashi Matsuda; Hiroshi Shimoda; Toshio Morikawa; Masayuki Yoshikawa
Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity.
Bioorganic & medicinal chemistry letters 2001;11(14):1839-42.
2001: Masayuki Yoshikawa; Toshiyuki Murakami; Akinobu Kishi; Tadashi Kageura; Hisashi Matsuda
Medicinal flowers. III. Marigold. (1): hypoglycemic, gastric emptying inhibitory, and gastroprotective principles and new oleanane-type triterpene oligoglycosides, calendasaponins A, B, C, and D, from Egyptian Calendula officinalis.
Chemical & pharmaceutical bulletin 2001;49(7):863-70.
2001: Toshiyuki Murakami; Akinobu Kishi; Hisashi Matsuda; M Hattori; Masayuki Yoshikawa
Medicinal foodstuffs. XXIV. Chemical constituents of the processed leaves of Apocynum venetum L.: absolute stereostructures of apocynosides I and II.
Chemical & pharmaceutical bulletin 2001;49(7):845-8.
2001: Tadashi Kageura; Hisashi Matsuda; Toshio Morikawa; Iwao Toguchida; Shoichi Harima; M Oda; Masayuki Yoshikawa
Inhibitors from rhubarb on lipopolysaccharide-induced nitric oxide production in macrophages: structural requirements of stilbenes for the activity.
Bioorganic & medicinal chemistry 2001;9(7):1887-93.
2001: Toshiyuki Murakami; K Hirano; Masayuki Yoshikawa
Medicinal foodstuffs. XXIII. Structures of new oleanane-type triterpene oligoglycosides, basellasaponins A, B, C, and D, from the fresh aerial parts of Basella rubra L.
Chemical & pharmaceutical bulletin 2001;49(6):776-9.
2001: Toshiyuki Murakami; H Oominami; Hisashi Matsuda; Masayuki Yoshikawa
Bioactive saponins and glycosides. XVIII. Nortriterpene and triterpene oligoglycosides from the fresh leaves of Euptelea polyandra Sieb. et Zucc. (2): Structures of eupteleasaponins VI, VI acetate, VII, VIII, IX, X, XI, and XII.
Chemical & pharmaceutical bulletin 2001;49(6):741-6.
2001: Hisashi Matsuda; Tadashi Kageura; M Oda; Toshio Morikawa; Y Sakamoto; Masayuki Yoshikawa
Effects of constituents from the bark of Magnolia obovata on nitric oxide production in lipopolysaccharide-activated macrophages.
Chemical & pharmaceutical bulletin 2001;49(6):716-20.
2001: Hisashi Matsuda; Toshiyuki Murakami; Akinobu Kishi; Masayuki Yoshikawa
Structures of withanosides I, II, III, IV, V, VI, and VII, new withanolide glycosides, from the roots of Indian Withania somnifera DUNAL. and inhibitory activity for tachyphylaxis to clonidine in isolated guinea-pig ileum.
Bioorganic & medicinal chemistry 2001;9(6):1499-507.
2001: Masayuki Yoshikawa; N Nishida; H Shimoda; M Takada; Y Kawahara; Hisashi Matsuda
[Polyphenol constituents from Salacia species: quantitative analysis of mangiferin with alpha-glucosidase and aldose reductase inhibitory activities].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2001;121(5):371-8.
2001: Hisashi Matsuda; Toshio Morikawa; Kiyofumi Ninomiya; Masayuki Yoshikawa
Hepatoprotective constituents from zedoariae rhizoma: absolute stereostructures of three new carabrane-type sesquiterpenes, curcumenolactones A, B, and C.
Bioorganic & medicinal chemistry 2001;9(4):909-16.
2001: Hisashi Matsuda; H Shimoda; Masayuki Yoshikawa
Dimeric sesquiterpene thioalkaloids with potent immunosuppressive activity from the rhizome of Nuphar pumilum: structural requirements of nuphar alkaloids for immunosuppressive activity.
Bioorganic & medicinal chemistry 2001;9(4):1031-5.
2001: Toshiyuki Murakami; K Kohno; Hisashi Matsuda; Masayuki Yoshikawa
Medicinal foodstuffs. XXII. Structures of oleanane-type triterpene oligoglycosides, pisumsaponins I and II, and kaurane-type diterpene oligoglycosides, pisumosides A and B, from green peas, the immature seeds of Pisum sativum L.
Chemical & pharmaceutical bulletin 2001;49(1):73-7.
2001: Hisashi Matsuda; T Ohta; A Kawaguchi; Masayuki Yoshikawa
Bioactive constituents of chinese natural medicines. VI. Moutan cortex. (2): structures and radical scavenging effects of suffruticosides A, B, C, D, and E and galloyl-oxypaeoniflorin.
Chemical & pharmaceutical bulletin 2001;49(1):69-72.
2001: Toshiyuki Murakami; A Emoto; Hisashi Matsuda; Masayuki Yoshikawa
Medicinal foodstuffs. XXI. Structures of new cucurbitane-type triterpene glycosides, goyaglycosides-a, -b, -c, -d, -e, -f, -g, and -h, and new oleanane-type triterpene saponins, goyasaponins I, II, and III, from the fresh fruit of Japanese Momordica charantia L.
Chemical & pharmaceutical bulletin 2001;49(1):54-63.
2001: Hisashi Matsuda; Toshio Morikawa; Iwao Toguchida; J Y Park; Shoichi Harima; Masayuki Yoshikawa
Antioxidant constituents from rhubarb: structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides.
Bioorganic & medicinal chemistry 2001;9(1):41-50.
2000: Hisashi Matsuda; Y Li; Masayuki Yoshikawa
Possible involvement of dopamine and dopamine2 receptors in the inhibitions of gastric emptying by escin Ib in mice.
Life sciences 2000;67(24):2921-7.
2000: Toshiyuki Murakami; J Nakamura; Tadashi Kageura; Hisashi Matsuda; Masayuki Yoshikawa
Bioactive saponins and glycosides. XVII. Inhibitory effect on gastric emptying and accelerating effect on gastrointestinal transit of tea saponins: structures of assamsaponins F, G, H, I, and J from the seeds and leaves of the tea plant.
Chemical & pharmaceutical bulletin 2000;48(11):1720-5.
2000: Toshiyuki Murakami; K Kohno; Akinobu Kishi; Hisashi Matsuda; Masayuki Yoshikawa
Medicinal foodstuffs. XIX. Absolute stereostructures of canavalioside, a new Ent-kaurane-type diterpene glycoside, and gladiatosides A1, A2, A3, B1, B2, B3, C1, and C2, new acylated flavonol glycosides, from sword bean, the seeds of Canavalia gladiata.
Chemical & pharmaceutical bulletin 2000;48(11):1673-80.
2000: Hisashi Matsuda; Toshiyuki Murakami; Norihisa Nishida; Tadashi Kageura; Masayuki Yoshikawa
Medicinal foodstuffs. XX. Vasorelaxant active constituents from the roots of Angelica furcijuga Kitagawa: structures of hyuganins A, B, C, and D.
Chemical & pharmaceutical bulletin 2000;48(10):1429-35.
2000: Masayuki Yoshikawa; T Ohta; A Kawaguchi; Hisashi Matsuda
Bioactive constituents of Chinese natural medicines. V. Radical scavenging effect of Moutan Cortex. (1): Absolute stereostructures of two monoterpenes, paeonisuffrone and paeonisuffral.
Chemical & pharmaceutical bulletin 2000;48(9):1327-31.
2000: Masayuki Yoshikawa; H Shimoda; T Uemura; Toshio Morikawa; Y Kawahara; Hisashi Matsuda
Alcohol absorption inhibitors from bay leaf (Laurus nobilis): structure-requirements of sesquiterpenes for the activity.
Bioorganic & medicinal chemistry 2000;8(8):2071-7.
2000: Masayuki Yoshikawa; Toshiyuki Murakami; H Oomiinami; Hisashi Matsuda
Bioactive saponins and glycosides. XVI. Nortriterpene oligoglycosides with gastroprotective activity from the fresh leaves of Euptelea polyandra Sieb. et Zucc. (1): structures of Eupteleasaponins I, II, III, IV, V, and V acetate.
Chemical & pharmaceutical bulletin 2000;48(7):1045-50.
2000: Masayuki Yoshikawa; T Uemura; H Shimoda; Akinobu Kishi; Y Kawahara; Hisashi Matsuda
Medicinal foodstuffs. XVIII. Phytoestrogens from the aerial part of Petroselinum crispum MIll. (Parsley) and structures of 6"-acetylapiin and a new monoterpene glycoside, petroside.
Chemical & pharmaceutical bulletin 2000;48(7):1039-44.
2000: T Murakami; A Kishi; Hisashi Matsuda; Masayuki Yoshikawa
Medicinal foodstuffs. XVII. Fenugreek seed. (3): structures of new furostanol-type steroid saponins, trigoneosides Xa, Xb, XIb, XIIa, XIIb, and XIIIa, from the seeds of Egyptian Trigonellafoenum-graecum L.
Chemical & pharmaceutical bulletin 2000;48(7):994-1000.
2000: Masayuki Yoshikawa; Toshio Morikawa; Iwao Toguchida; Shoichi Harima; Hisashi Matsuda
Medicinal flowers. II. Inhibitors of nitric oxide production and absolute stereostructures of five new germacrane-type sesquiterpenes, kikkanols D, D monoacetate, E, F, and F monoacetate from the flowers of Chrysanthemum indicum L.
Chemical & pharmaceutical bulletin 2000;48(5):651-6.
2000: Hisashi Matsuda; T Kagerura; Iwao Toguchida; H Ueda; Toshio Morikawa; Masayuki Yoshikawa
Inhibitory effects of sesquiterpenes from bay leaf on nitric oxide production in lipopolysaccharide-activated macrophages: structure requirement and role of heat shock protein induction.
Life sciences 2000;66(22):2151-7.
2000: Hisashi Matsuda; Tadashi Kageura; Toshio Morikawa; Iwao Toguchida; Shoichi Harima; Masayuki Yoshikawa
Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages.
Bioorganic & medicinal chemistry letters 2000;10(4):323-7.
2000: Hisashi Matsuda; Y Li; Masayuki Yoshikawa
Possible involvement of 5-HT and 5-HT2 receptors in acceleration of gastrointestinal transit by escin Ib in mice.
Life sciences 2000;66(23):2233-8.
2000: Hisashi Matsuda; Y Li; Masayuki Yoshikawa
Roles of endogenous prostaglandins and nitric oxide in inhibitions of gastric emptying and accelerations of gastrointestinal transit by escins Ia, Ib, IIa, and IIb in mice.
Life sciences 2000;66(3):PL 41-6.
1999: Toshiyuki Murakami; J Nakamura; Hisashi Matsuda; Masayuki Yoshikawa
Bioactive saponins and glycosides. XV. Saponin constituents with gastroprotective effect from the seeds of tea plant, Camellia sinensis L. var. assamica Pierre, cultivated in Sri Lanka: structures of assamsaponins A, B, C, D, and E.
Chemical & pharmaceutical bulletin 1999;47(12):1759-64.
1999: Hisashi Matsuda; H Shimoda; T Uemura; T Ueda; J Yamahara; Masayuki Yoshikawa
Chemical constituents from the leaves of Hydrangea macrophylla var. thunbergii (III): Absolute stereostructures of hydramacrosides A and B, secoiridoid glucoside complexes with inhibitory activity on histamine release.
Chemical & pharmaceutical bulletin 1999;47(12):1753-8.
1999: Hisashi Matsuda; Toshiyuki Murakami; A Ikebata; J Yamahara; Masayuki Yoshikawa
Bioactive saponins and glycosides. XIV. Structure elucidation and immunological adjuvant activity of novel protojujubogenin type triterpene bisdesmosides, protojujubosides A, B, and B1, from the seeds of Zizyphus jujuba var. spinosa (Zizyphi Spinosi Semen).
Chemical & pharmaceutical bulletin 1999;47(12):1744-8.
1999: Hisashi Matsuda; Toshiyuki Murakami; K Yashiro; J Yamahara; Masayuki Yoshikawa
Antidiabetic principles of natural medicines. IV. Aldose reductase and qlpha-glucosidase inhibitors from the roots of Salacia oblonga Wall. (Celastraceae): structure of a new friedelane-type triterpene, kotalagenin 16-acetate.
Chemical & pharmaceutical bulletin 1999;47(12):1725-9.
1999: Hisashi Matsuda; Tadashi Kageura; Iwao Toguchida; Toshiyuki Murakami; Akinobu Kishi; Masayuki Yoshikawa
Effects of sesquiterpenes and triterpenes from the rhizome of Alisma orientale on nitric oxide production in lipopolysaccharide-activated macrophages: absolute stereostructures of alismaketones-B 23-acetate and -C 23-acetate.
Bioorganic & medicinal chemistry letters 1999;9(21):3081-6.
1999: Hisashi Matsuda; H Shimoda; T Uemura; Masayuki Yoshikawa
Preventive effect of sesquiterpenes from bay leaf on blood ethanol elevation in ethanol-loaded rat: structure requirement and suppression of gastric emptying.
Bioorganic & medicinal chemistry letters 1999;9(18):2647-52.
1999: Y Li; Hisashi Matsuda; S Wen; J Yamahara; Masayuki Yoshikawa
Structure-related enhancing activity of escins Ia, Ib, IIa and IIb on magnesium absorption in mice.
Bioorganic & medicinal chemistry letters 1999;9(17):2473-8.
1999: Hisashi Matsuda; H Shimoda; Tadashi Kageura; Masayuki Yoshikawa
The role of thunberginol A, an isocoumarin constituent of Hydrangeae Dulcis Folium, on the signal transmission pathway for rat mast cell degranulation.
Biological & pharmaceutical bulletin 1999;22(9):925-31.
1999: Hisashi Matsuda; Y Li; Masayuki Yoshikawa
Effects of escins Ia, Ib, IIa, and IIb from horse chestnuts on gastrointestinal transit and ileus in mice.
Bioorganic & medicinal chemistry 1999;7(8):1737-41.
1999: Hisashi Matsuda; H Shimoda; J Yamahara; Masayuki Yoshikawa
Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats.
Biological & pharmaceutical bulletin 1999;22(8):870-2.
1999: Hisashi Matsuda; H Shimoda; Masayuki Yoshikawa
Structure-requirements of isocoumarins, phthalides, and stilbenes from Hydrangeae Dulcis Folium for inhibitory activity on histamine release from rat peritoneal mast cells.
Bioorganic & medicinal chemistry 1999;7(7):1445-50.
1999: Y Li; Hisashi Matsuda; Masayuki Yoshikawa
Effects of oleanolic acid glycosides on gastrointestinal transit and ileus in mice.
Bioorganic & medicinal chemistry 1999;7(6):1201-5.
1999: Hisashi Matsuda; Y Li; Masayuki Yoshikawa
Gastroprotections of escins Ia, Ib, IIa, and IIb on ethanol-induced gastric mucosal lesions in rats.
European journal of pharmacology 1999;373(1):63-70.
1999: Hisashi Matsuda; Y Li; J Yamahara; Masayuki Yoshikawa
Inhibition of gastric emptying by triterpene saponin, momordin Ic, in mice: roles of blood glucose, capsaicin-sensitive sensory nerves, and central nervous system.
The Journal of pharmacology and experimental therapeutics 1999;289(2):729-34.
1999: Hisashi Matsuda; Y Li; Toshiyuki Murakami; J Yamahara; Masayuki Yoshikawa
Effects of escins Ia, Ib, IIa, and IIb from horse chestnuts on gastric emptying in mice.
European journal of pharmacology 1999;368(2-3):237-43.
1999: Masayuki Yoshikawa; Toshio Morikawa; Toshiyuki Murakami; Iwao Toguchida; Shoichi Harima; Hisashi Matsuda
Medicinal flowers. I. Aldose reductase inhibitors and three new eudesmane-type sesquiterpenes, kikkanols A, B, and C, from the flowers of Chrysanthemum indicum L.
Chemical & pharmaceutical bulletin 1999;47(3):340-5.
1999: Hisashi Matsuda; Y Li; Toshiyuki Murakami; J Yamahara; Masayuki Yoshikawa
Structure-related inhibitory activity of oleanolic acid glycosides on gastric emptying in mice.
Bioorganic & medicinal chemistry 1999;7(2):323-7.
1999: Hisashi Matsuda; Y Li; Masayuki Yoshikawa
Roles of capsaicin-sensitive sensory nerves, endogenous nitric oxide, sulfhydryls, and prostaglandins in gastroprotection by momordin Ic, an oleanolic acid oligoglycoside, on ethanol-induced gastric mucosal lesions in rats.
Life sciences 1999;65(2):PL27-32.
1999: Masayuki Yoshikawa; Toshiyuki Murakami; K Otuki; J Yamahara; Hisashi Matsuda
[Bioactive saponins and glycosides. XIII. Horse chestnut. (3): Quantitative analysis of escins Ia, Ib, IIa, and IIb by means of high performance liquid chromatography].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1999;119(1):81-7.
1998: Hisashi Matsuda; A Ishikado; Norihisa Nishida; Kiyofumi Ninomiya; H Fujiwara; Y Kobayashi; Masayuki Yoshikawa
Hepatoprotective, superoxide scavenging, and antioxidative activities of aromatic constituents from the bark of Betula platyphylla var. japonica.
Bioorganic & medicinal chemistry letters 1998;8(21):2939-44.
1998: Masayuki Yoshikawa; Toshiyuki Murakami; J Yamahara; Hisashi Matsuda
Bioactive saponins and glycosides. XII. Horse chestnut. (2): Structures of escins IIIb, IV, V, and VI and isoescins Ia, Ib, and V, acylated polyhydroxyoleanene triterpene oligoglycosides, from the seeds of horse chestnut tree (Aesculus hippocastanum L., Hippocastanaceae).
Chemical & pharmaceutical bulletin 1998;46(11):1764-9.
1998: Hisashi Matsuda; Y Li; Toshiyuki Murakami; N Matsumura; J Yamahara; Masayuki Yoshikawa
Antidiabetic principles of natural medicines. III. Structure-related inhibitory activity and action mode of oleanolic acid glycosides on hypoglycemic activity.
Chemical & pharmaceutical bulletin 1998;46(9):1399-403.
1998: Hisashi Matsuda; Toshiyuki Murakami; Tadashi Kageura; Kiyofumi Ninomiya; Iwao Toguchida; Norihisa Nishida; Masayuki Yoshikawa
Hepatoprotective and nitric oxide production inhibitory activities of coumarin and polyacetylene constituents from the roots of Angelica furcijuga.
Bioorganic & medicinal chemistry letters 1998;8(16):2191-6.
1998: H Shimoda; Hisashi Matsuda; J Yamahara; Masayuki Yoshikawa
Development of bioactive functions in Hydrangeae Dulcis Folium. VII. Immunomodulatory activities of thunberginol A and related compounds on lymphocyte proliferation.
Biological & pharmaceutical bulletin 1998;21(8):809-13.
1998: Masayuki Yoshikawa; Toshiyuki Murakami; K Yashiro; Hisashi Matsuda
Kotalanol, a potent alpha-glucosidase inhibitor with thiosugar sulfonium sulfate structure, from antidiabetic ayurvedic medicine Salacia reticulata.
Chemical & pharmaceutical bulletin 1998;46(8):1339-40.
1998: Hisashi Matsuda; Toshiyuki Murakami; Y Li; J Yamahara; Masayuki Yoshikawa
Mode of action of escins Ia and IIa and E,Z-senegin II on glucose absorption in gastrointestinal tract.
Bioorganic & medicinal chemistry 1998;6(7):1019-23.
1998: Masayuki Yoshikawa; Toshiyuki Murakami; H Shimada; S Yoshizumi; M Saka; J Yamahara; Hisashi Matsuda
Medicinal foodstuffs. XIV. On the bioactive constituents of moroheiya. (2): New fatty acids, corchorifatty acids A, B, C, D, E, and F, from the leaves of Corchorus olitorius L. (Tiliaceae): structures and inhibitory effect on NO production in mouse peritoneal macrophages.
Chemical & pharmaceutical bulletin 1998;46(6):1008-14.
1998: Masayuki Yoshikawa; Toshiyuki Murakami; Akinobu Kishi; T Sakurama; H Matsuda; M Nomura; Hisashi Matsuda; M Kubo
Novel indole S,O-bisdesmoside, calanthoside, the precursor glycoside of tryptanthrin, indirubin, and isatin, with increasing skin blood flow promoting effects, from two Calanthe species (Orchidaceae).
Chemical & pharmaceutical bulletin 1998;46(5):886-8.
1998: Masayuki Yoshikawa; Toshiyuki Murakami; H Komatsu; Hisashi Matsuda
Medicinal foodstuffs. XII. Saponin constituents with adjuvant activity from hyacinth bean, the seeds of Dolichos lablab L. (1): Structures of lablabosides A, B, and C.
Chemical & pharmaceutical bulletin 1998;46(5):812-6.
1998: S Yoshizumi; Toshiyuki Murakami; M Kadoya; Hisashi Matsuda; J Yamahara; Masayuki Yoshikawa
[Medicinal foodstuffs. XI. Histamine release inhibitors from wax gourd, the fruits of Benincasa hispida Cogn].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1998;118(5):188-92.
1998: Masayuki Yoshikawa; Toshiyuki Murakami; K Yashiro; J Yamahara; Hisashi Matsuda; R Saijoh; O Tanaka
Bioactive saponins and glycosides. XI. Structures of new dammarane-type triterpene oligoglycosides, quinquenosides I, II, III, IV, and V, from American ginseng, the roots of Panax quinquefolium L.
Chemical & pharmaceutical bulletin 1998;46(4):647-54.
1998: Hisashi Matsuda; Kiyofumi Ninomiya; Toshio Morikawa; Masayuki Yoshikawa
Inhibitory effect and action mechanism of sesquiterpenes from Zedoariae Rhizoma on D-galactosamine/lipopolysaccharide-induced liver injury.
Bioorganic & medicinal chemistry letters 1998;8(4):339-44.
1998: Hisashi Matsuda; H Shimoda; J Yamahara; Masayuki Yoshikawa
Immunomodulatory activity of thunberginol A and related compounds isolated from Hydrangeae Dulcis Folium on splenocyte proliferation activated by mitogens.
Bioorganic & medicinal chemistry letters 1998;8(3):215-20.
1998: Hisashi Matsuda; Y Li; Toshiyuki Murakami; J Yamahara; Masayuki Yoshikawa
Protective effects of oleanolic acid oligoglycosides on ethanol- or indomethacin-induced gastric mucosal lesions in rats.
Life sciences 1998;63(17):PL245-50.
1998: Masayuki Yoshikawa; H Shimada; Norihisa Nishida; Y Li; Iwao Toguchida; J Yamahara; Hisashi Matsuda
Antidiabetic principles of natural medicines. II. Aldose reductase and alpha-glucosidase inhibitors from Brazilian natural medicine, the leaves of Myrcia multiflora DC. (Myrtaceae): structures of myrciacitrins I and II and myrciaphenones A and B.
Chemical & pharmaceutical bulletin 1998;46(1):113-9.
1997: Masayuki Yoshikawa; Toshiyuki Murakami; Hisashi Matsuda
Medicinal foodstuffs. X. Structures of new triterpene glycosides, gymnemosides-c, -d, -e, and -f, from the leaves of Gymnema sylvestre R. Br.: influence of gymnema glycosides on glucose uptake in rat small intestinal fragments.
Chemical & pharmaceutical bulletin 1997;45(12):2034-8.
1997: Masayuki Yoshikawa; Toshiyuki Murakami; M Kadoya; Y Li; N Murakami; J Yamahara; Hisashi Matsuda
Medicinal foodstuffs. IX. The inhibitors of glucose absorption from the leaves of Gymnema sylvestre R. BR. (Asclepiadaceae): structures of gymnemosides a and b.
Chemical & pharmaceutical bulletin 1997;45(10):1671-6.
1997: Hisashi Matsuda; Y Li; Toshiyuki Murakami; Kiyofumi Ninomiya; J Yamahara; Masayuki Yoshikawa
Effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L., on acute inflammation in animals.
Biological & pharmaceutical bulletin 1997;20(10):1092-5.
1997: Masayuki Yoshikawa; H Shimada; S Horikawa; Toshiyuki Murakami; H Shimoda; J Yamahara; Hisashi Matsuda
Bioactive constituents of Chinese natural medicines. IV. Rhodiolae radix. (2).: On the histamine release inhibitors from the underground part of Rhodiola sacra (Prain ex Hamet) S. H. Fu (Crassulaceae): chemical structures of rhodiocyanoside D and sacranosides A and B.
Chemical & pharmaceutical bulletin 1997;45(9):1498-503.
1997: Masayuki Yoshikawa; H Shimada; Toshio Morikawa; S Yoshizumi; N Matsumura; Toshiyuki Murakami; Hisashi Matsuda; K Hori; J Yamahara
Medicinal foodstuffs. VII. On the saponin constituents with glucose and alcohol absorption-inhibitory activity from a food garnish "Tonburi", the fruit of Japanese Kochia scoparia (L.) Schrad.: structures of scoparianosides A, B, and C.
Chemical & pharmaceutical bulletin 1997;45(8):1300-5.
1997: Masayuki Yoshikawa; Toshiyuki Murakami; A Ikebata; S Wakao; N Murakami; Hisashi Matsuda; J Yamahara
Bioactive saponins and glycosides. X. On the constituents of zizyphi spinosi semen, the seeds of Zizyphus jujuba Mill. var. spinosa Hu (1): structures and histamine release-inhibitory effect of jujubosides A1 and C and acetyljujuboside B.
Chemical & pharmaceutical bulletin 1997;45(7):1186-92.
1997: Masayuki Yoshikawa; Toshiyuki Murakami; T Ueno; K Yashiro; N Hirokawa; N Murakami; J Yamahara; Hisashi Matsuda; R Saijoh; O Tanaka
Bioactive saponins and glycosides. VIII. Notoginseng (1): new dammarane-type triterpene oligoglycosides, notoginsenosides-A, -B, -C, and -D, from the dried root of Panax notoginseng (Burk.) F.H. Chen.
Chemical & pharmaceutical bulletin 1997;45(6):1039-45.
1997: Hisashi Matsuda; Toshiyuki Murakami; H Shimada; N Matsumura; Masayuki Yoshikawa; J Yamahara
Inhibitory mechanisms of oleanolic acid 3-O-monodesmosides on glucose absorption in rats.
Biological & pharmaceutical bulletin 1997;20(6):717-9.
1997: Masayuki Yoshikawa; H Shimada; H Komatsu; T Sakurama; Norihisa Nishida; J Yamahara; H Shimoda; Hisashi Matsuda; Tadato Tani
Medicinal foodstuffs. VI. 1) Histamine release inhibitors from kidney bean, the seeds of Phaseolus vulgaris L.: chemical structures of sandosaponins A and B.
Chemical & pharmaceutical bulletin 1997;45(5):877-82.
1997: Masayuki Yoshikawa; H Shimada; M Saka; S Yoshizumi; J Yamahara; Hisashi Matsuda
Medicinal foodstuffs. V. Moroheiya. (1): Absolute stereostructures of corchoionosides A, B, and C, histamine release inhibitors from the leaves of Vietnamese Corchorus olitorius L. (Tiliaceae).
Chemical & pharmaceutical bulletin 1997;45(3):464-9.
1997: Masayuki Yoshikawa; Toshiyuki Murakami; T Ueda; S Yoshizumi; Kiyofumi Ninomiya; N Murakami; Hisashi Matsuda; M Saito; W Fujii; T Tanaka; J Yamahara
[Bioactive constituents of Chinese natural medicines. III. Absolute stereostructures of new dihydroflavonols, hovenitins I, II, and III, isolated from hoveniae semen seu fructus, the seed and fruit of Hovenia dulcis THUNB. (Rhamnaceae): inhibitory effect on alcohol-induced muscular relaxation and hepatoprotective activity].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1997;117(2):108-18.
1997: Masayuki Yoshikawa; Toshiyuki Murakami; H Komatsu; N Murakami; J Yamahara; Hisashi Matsuda
Medicinal foodstuffs. IV. Fenugreek seed. (1): structures of trigoneosides Ia, Ib, IIa, IIb, IIIa, and IIIb, new furostanol saponins from the seeds of Indian Trigonella foenum-graecum L.
Chemical & pharmaceutical bulletin 1997;45(1):81-7.
1996: Masayuki Yoshikawa; H Shimada; H Shimoda; N Murakami; J Yamahara; Hisashi Matsuda
Bioactive constituents of Chinese natural medicines. II. Rhodiolae radix. (1). Chemical structures and antiallergic activity of rhodiocyanosides A and B from the underground part of Rhodiola quadrifida (Pall.) Fisch. et Mey. (Crassulaceae).
Chemical & pharmaceutical bulletin 1996;44(11):2086-91.
1996: Masayuki Yoshikawa; Toshiyuki Murakami; E Harada; N Murakami; J Yamahara; Hisashi Matsuda
Bioactive saponins and glycosides. VII. On the hypoglycemic principles from the root cortex of Aralia elata Seem.: structure related hypoglycemic activity of oleanolic acid oligoglycoside.
Chemical & pharmaceutical bulletin 1996;44(10):1923-7.
1996: Masayuki Yoshikawa; Toshiyuki Murakami; E Harada; N Murakami; J Yamahara; Hisashi Matsuda
Bioactive saponins and glycosides. VI. Elatosides A and B, potent inhibitors of ethanol absorption, from the bark of Aralia elata SEEM. (Araliaceae): the structure-requirement in oleanolic acid glucuronide-saponins for the inhibitory activity.
Chemical & pharmaceutical bulletin 1996;44(10):1915-22.
1996: Masayuki Yoshikawa; Toshiyuki Murakami; S Yoshizumi; N Murakami; J Yamahara; Hisashi Matsuda
Bioactive saponins and glycosides. V. Acylated polyhydroxyolean-12-ene triterpene oligoglycosides, camelliasaponins A1, A2, B1, B2, C1, and C2, from the seeds of Camellia japonica L.: structures and inhibitory activity on alcohol absorption.
Chemical & pharmaceutical bulletin 1996;44(10):1899-907.
1996: Masayuki Yoshikawa; H Shimada; N Yagi; N Murakami; H Shimoda; J Yamahara; Hisashi Matsuda
Development of bioactive functions in Hydrangeae dulcis folium. VI. Syntheses of thunberginols A and F and their 3'-deoxy-derivatives using regiospecific lactonization of stilbene carboxylic acid: structures and inhibitory activity on histamine release of hydramacrophyllols A and B.
Chemical & pharmaceutical bulletin 1996;44(10):1890-8.
1996: Masayuki Yoshikawa; Toshiyuki Murakami; T Ueda; Hisashi Matsuda; J Yamahara; N Murakami
Bioactive saponins and glycosides. IV. Four methyl-migrated 16,17-seco-dammarane triterpene gylcosides from Chinese natural medicine, hoveniae semen seu fructus, the seeds and fruit of Hovenia dulcis THUNB.: absolute stereostructures and inhibitory activity on histamine release of hovenidulciosides A1, A2, B1, and B2.
Chemical & pharmaceutical bulletin 1996;44(9):1736-43.
1996: Masayuki Yoshikawa; H Shimada; Hisashi Matsuda; J Yamahara; N Murakami
Bioactive constituents of Chinese natural medicines. I. New sesquiterpene ketones with vasorelaxant effect from Chinese moxa, the processed leaves of Artemisia argyi Levl. et Vant.: moxartenone and moxartenolide.
Chemical & pharmaceutical bulletin 1996;44(9):1656-62.
1996: Masayuki Yoshikawa; Toshiyuki Murakami; Hisashi Matsuda; J Yamahara; N Murakami; I Kitagawa
Bioactive saponins and glycosides. III. Horse chestnut. (1): The structures, inhibitory effects on ethanol absorption, and hypoglycemic activity of escins Ia, Ib, IIa, IIb, and IIIa from the seeds of Aesculus hippocastanum L.
Chemical & pharmaceutical bulletin 1996;44(8):1454-64.
1996: Masayuki Yoshikawa; Hisashi Matsuda; H Shimoda; H Shimada; E Harada; Y Naitoh; A Miki; J Yamahara; N Murakami
Development of bioactive functions in hydrangeae dulcis folium. V. On the antiallergic and antimicrobial principles of hydrangeae dulcis folium. (2). Thunberginols C, D, and E, thunberginol G 3'-O-glucoside, (-)-hydrangenol 4'-o-glucoside, and (+)-hydrangenol 4'-O-glucoside.
Chemical & pharmaceutical bulletin 1996;44(8):1440-7.
1996: Masayuki Yoshikawa; Toshiyuki Murakami; Hisashi Matsuda; T Ueno; M Kadoya; J Yamahara; N Murakami
Bioactive saponins and glycosides. II. Senegae Radix. (2): Chemical structures, hypoglycemic activity, and ethanol absorption-inhibitory effect of E-senegasaponin c, Z-senegasaponin c, and Z-senegins II, III, and IV.
Chemical & pharmaceutical bulletin 1996;44(7):1305-13.
1996: N Murakami; M Saka; H Shimada; Hisashi Matsuda; J Yamahara; Masayuki Yoshikawa
New bioactive monoterpene glycosides from Paeoniae Radix.
Chemical & pharmaceutical bulletin 1996;44(6):1279-81.
1996: Masayuki Yoshikawa; Toshiyuki Murakami; M Kadoya; Hisashi Matsuda; O Muraoka; J Yamahara; N Murakami
Medicinal foodstuff. III. Sugar beet. (1): Hypoglycemic oleanolic acid oligoglycosides, betavulgarosides I, II, III, and IV, from the root of Beta vulgaris L. (Chenopodiaceae).
Chemical & pharmaceutical bulletin 1996;44(6):1212-7.
1996: Masayuki Yoshikawa; S Yoshizumi; Toshiyuki Murakami; Hisashi Matsuda; J Yamahara; N Murakami
Medicinal foodstuffs. II. On the bioactive constituents of the tuber of Sagittaria trifolia L. (Kuwai, Alismataceae): absolute stereostructures of trifoliones A, B, C, and D, sagittariosides a and b, and arabinothalictoside.
Chemical & pharmaceutical bulletin 1996;44(3):492-9.
1996: N Murakami; Toshiyuki Murakami; M Kadoya; Hisashi Matsuda; J Yamahara; Masayuki Yoshikawa
New hypoglycemic constituents in "gymnemic acid" from Gymnema sylvestre.
Chemical & pharmaceutical bulletin 1996;44(2):469-71.
1995: Masayuki Yoshikawa; Toshiyuki Murakami; T Ueno; M Kadoya; Hisashi Matsuda; J Yamahara; N Murakami
Bioactive saponins and glycosides. I. Senegae radix. (1): E-senegasaponins a and b and Z-senegasaponins a and b, their inhibitory effect on alcohol absorption and hypoglycemic activity.
Chemical & pharmaceutical bulletin 1995;43(12):2115-22.
1995: Masayuki Yoshikawa; S Yoshizumi; T Ueno; Hisashi Matsuda; Toshiyuki Murakami; J Yamahara; N Murakami
Medicinal foodstuffs. I. Hypoglycemic constituents from a garnish foodstuff "taranome," the young shoot of Aralia elata SEEM.: elatosides G, H, I, J, and K.
Chemical & pharmaceutical bulletin 1995;43(11):1878-82.
1995: Masayuki Yoshikawa; Y Yokokawa; Y Okuno; N Yagi; N Murakami
Syntheses, immunosuppressive activity, and structure-activity relationships of myriocin analogs, 2-epi-myriocin, 14-deoxomyriocin, Z-14-deoxyomyriocin, and nor-deoxomyriocins.
Chemical & pharmaceutical bulletin 1995;43(10):1647-53.
1995: Masayuki Yoshikawa; S Yamaguchi; H Nishisaka; J Yamahara; N Murakami
Chemical constituents of Chinese natural medicine, morindae radix, the dried roots of morinda officinalis how.: structures of morindolide and morofficinaloside.
Chemical & pharmaceutical bulletin 1995;43(9):1462-5.
1995: Masayuki Yoshikawa; H Shimada; H Shimoda; Hisashi Matsuda; J Yamahara; N Murakami
Rhodiocyanosides A and B, new antiallergic cyanoglycosides from Chinese natural medicine "si lie hong jing tian", the underground part of Rhodiola quadrifida (Pall.) Fisch. et Mey.
Chemical & pharmaceutical bulletin 1995;43(7):1245-7.
1995: J Yamahara; Hisashi Matsuda; H Shimoda; N Wariishi; N Yagi; N Murakami; Masayuki Yoshikawa
[Effects of thunberginol A contained in Hydrangeae dulcis forium on types I-IV allergies].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1995;105(5):365-79.
1995: Masayuki Yoshikawa; T Ueda; O Muraoka; H Aoyama; Hisashi Matsuda; H Shimoda; J Yamahara; N Murakami
Absolute stereostructures of hovenidulciosides A1 and A2, bioactive novel triterpene glycosides from hoveniae semen seu fructus, the seeds and fruit of Hovenia dulcis Thunb.
Chemical & pharmaceutical bulletin 1995;43(3):532-4.
1995: Masayuki Yoshikawa; Toshiyuki Murakami; T Ueno; M Kadoya; Hisashi Matsuda; J Yamahara; N Murakami
E-senegasaponins A and B, Z-senegasaponins A and B, Z-senegins II and III, new type inhibitors of ethanol absorption in rats from senegae radix, the roots of Polygala senega L. var latifolia Torrey et Gray.
Chemical & pharmaceutical bulletin 1995;43(2):350-2.
1994: Masayuki Yoshikawa; Y Yokokawa; Y Okuno; N Yagi; N Murakami
Synthesis of new immunosuppressive myriocin analogs, 2-epi-myriocin, 14-deoxomyriocin, Z-14-deoxomyriocin, and nor-deoxomyriocins: their structure-activity relationships.
Chemical & pharmaceutical bulletin 1994;42(12):2662-4.
1994: Masayuki Yoshikawa; S Yamaguchi; Hisashi Matsuda; N Tanaka; J Yamahara; N Murakami
Crude drugs from aquatic plants. V. On the constituents of alismatis rhizoma. (3). Stereostructures of water-soluble bioactive sesquiterpenes, sulfoorientalols a, b, c, and d, from Chinese alismatis rhizoma.
Chemical & pharmaceutical bulletin 1994;42(12):2430-5.
1994: Masayuki Yoshikawa; E Harada; Y Naitoh; K Inoue; Hisashi Matsuda; H Shimoda; J Yamahara; N Murakami
Development of bioactive functions in hydrangeae dulcis folium. III. On the antiallergic and antimicrobial principles of hydrangeae dulcis folium. (1). Thunberginols A, B, and F.
Chemical & pharmaceutical bulletin 1994;42(11):2225-30.
1994: Masayuki Yoshikawa; S Yamaguchi; Hisashi Matsuda; Y Kohda; H Ishikawa; N Tanaka; J Yamahara; N Murakami
Crude drugs from aquatic plants. IV. On the constituents of alismatis rhizoma. (2). Stereostructures of bioactive sesquiterpenes, alismol, alismoxide, orientalols A, B, and C, from Chinese alismatis rhizoma.
Chemical & pharmaceutical bulletin 1994;42(9):1813-6.
1994: Masayuki Yoshikawa; T Ueda; Hisashi Matsuda; J Yamahara; N Murakami
Absolute stereostructures of hydramacrosides A and B, new bioactive secoiridoid glucoside complexes from the leaves of Hydrangea macrophylla Seringe var. thunbergii Makino.
Chemical & pharmaceutical bulletin 1994;42(8):1691-3.
1994: Masayuki Yoshikawa; E Harada; Toshiyuki Murakami; Hisashi Matsuda; N Wariishi; J Yamahara; N Murakami; I Kitagawa
Escins-Ia, Ib, IIa, IIb, and IIIa, bioactive triterpene oligoglycosides from the seeds of Aesculus hippocastanum L.: their inhibitory effects on ethanol absorption and hypoglycemic activity on glucose tolerance test.
Chemical & pharmaceutical bulletin 1994;42(6):1357-9.
1994: Masayuki Yoshikawa; Hisashi Matsuda; E Harada; Toshiyuki Murakami; N Wariishi; J Yamahara; N Murakami
Elatoside E, a new hypoglycemic principle from the root cortex of Aralia elata Seem.: structure-related hypoglycemic activity of oleanolic acid glycosides.
Chemical & pharmaceutical bulletin 1994;42(6):1354-6.
1994: Masayuki Yoshikawa; S Yamaguchi; K Kunimi; Hisashi Matsuda; Y Okuno; J Yamahara; N Murakami
Stomachic principles in ginger. III. An anti-ulcer principle, 6-gingesulfonic acid, and three monoacyldigalactosylglycerols, gingerglycolipids A, B, and C, from Zingiberis Rhizoma originating in Taiwan.
Chemical & pharmaceutical bulletin 1994;42(6):1226-30.
1994: J Yamahara; Hisashi Matsuda; H Shimoda; H Ishikawa; S Kawamori; N Wariishi; E Harada; N Murakami; Masayuki Yoshikawa
[Development of bioactive functions in hydrangeae dulcis folium. II. Antiulcer, antiallergy, and cholagoic effects of the extract from hydrangeae dulcis folium].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1994;114(6):401-13.
1994: Masayuki Yoshikawa; S Yamaguchi; N Chatani; Y Nishino; T Matsuoka; J Yamahara; N Murakami; Hisashi Matsuda; M Kubo
[Crude drugs from aquatic plants. III. Quantitative analysis of triterpene constituents in alismatis rhizoma by means of high performance liquid chromatography on the chemical change of the constituents during alismatis rhizoma processing].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1994;114(4):241-7.
1994: Masayuki Yoshikawa; Y Yokokawa; Y Okuno; N Murakami
Total synthesis of a novel immunosuppressant, myriocin (thermozymocidin, ISP-I), and Z-myriocin.
Chemical & pharmaceutical bulletin 1994;42(4):994-6.
1994: Masayuki Yoshikawa; N Chatani; E Harada; Y Nishino; J Yamahara; N Murakami
[Quantitative analysis of dihydroisocoumarin constituents of Hydrangeae Dulcis Folium by means of high performance liquid chromatography. Chemical characterization of the processing, distribution in plant, and seasonal fluctuation].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1994;114(3):176-81.
1994: Masayuki Yoshikawa; E Harada; Toshiyuki Murakami; Hisashi Matsuda; J Yamahara; N Murakami
Camelliasaponins B1, B2, C1 and C2, new type inhibitors of ethanol absorption in rats from the seeds of Camellia japonica L.
Chemical & pharmaceutical bulletin 1994;42(3):742-4.
1993: Masayuki Yoshikawa; E Harada; Hisashi Matsuda; Toshiyuki Murakami; J Yamahara; N Murakami
Elatosides A and B, potent inhibitors of ethanol absorption in rats from the bark of Aralia elata Seem: the structure-activity relationships of oleanolic acid oligoglycosides.
Chemical & pharmaceutical bulletin 1993;41(11):2069-71.
1993: Masayuki Yoshikawa; S Yamaguchi; Toshiyuki Murakami; Hisashi Matsuda; J Yamahara; N Murakami
Absolute stereostructures of trifoliones A, B, C, and D, new biologically active diterpenes from the tuber of Sagittaria trifolia L.
Chemical & pharmaceutical bulletin 1993;41(9):1677-9.
1993: Masayuki Yoshikawa; Y Fukuda; S Hatakeyama; N Tanaka; Hisashi Matsuda; J Yamahara; N Murakami
Sulfoorientalols a, b, c, and d, four new biologically active sesquiterpenes from Alismatis rhizoma.
Chemical & pharmaceutical bulletin 1993;41(6):1194-6.
1993: Masayuki Yoshikawa; Y Fukuda; S Hatakeyama; N Murakami; J Yamahara; T Taniyama; T Hayashi; I Kitagawa
[Chemical fluctuation of the constituents during the drying of Ginseng radix and Ginseng radix Rubra. Crude drug processing by far-infrared treatment].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1993;113(6):460-7.
1993: Masayuki Yoshikawa; S Hatakeyama; N Chatani; Y Nishino; J Yamahara
[Qualitative and quantitative analysis of bioactive principles in Zingiberis Rhizoma by means of high performance liquid chromatography and gas liquid chromatography. On the evaluation of Zingiberis Rhizoma and chemical change of constituents during Zingiberis Rhizoma processing].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1993;113(4):307-15.
1993: Masayuki Yoshikawa; S Hatakeyama; Y Inoue; J Yamahara
Saussureamines A, B, C, D, and E, new anti-ulcer principles from Chinese Saussureae Radix.
Chemical & pharmaceutical bulletin 1993;41(1):214-6.
1992: Masayuki Yoshikawa; E Uchida; N Chatani; H Kobayashi; Y Naitoh; Y Okuno; Hisashi Matsuda; J Yamahara; N Murakami
Thunberginols C, D, and E, new antiallergic and antimicrobial dihydroisocoumarins, and thunberginol G 3'-O-glucoside and (-)-hydrangenol 4'-O-glucoside, new dihydroisocoumarin glycosides, from Hydrangeae Dulcis Folium.
Chemical & pharmaceutical bulletin 1992;40(12):3352-4.
1992: J Yamahara; S Hatakeyama; K Taniguchi; M Kawamura; Masayuki Yoshikawa
[Stomachic principles in ginger. II. Pungent and anti-ulcer effects of low polar constituents isolated from ginger, the dried rhizoma of Zingiber officinale Roscoe cultivated in Taiwan. The absolute stereostructure of a new diarylheptanoid].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1992;112(9):645-55.
1992: Masayuki Yoshikawa; E Uchida; A Kawaguchi; I Kitagawa; J Yamahara
Galloyl-oxypaeoniflorin, suffruticosides A, B, C, and D, five new antioxidative glycosides, and suffruticoside E, A paeonol glycoside, from Chinese moutan cortex.
Chemical & pharmaceutical bulletin 1992;40(8):2248-50.
1992: Masayuki Yoshikawa; S Hatakeyama; K Taniguchi; H Matuda; J Yamahara
6-Gingesulfonic acid, a new anti-ulcer principle, and gingerglycolipids A, B, and C, three new monoacyldigalactosylglycerols, from zingiberis rhizoma originating in Taiwan.
Chemical & pharmaceutical bulletin 1992;40(8):2239-41.