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Tamotsu Yoshimori
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17
noda, takeshi
13
Mizushima, Noboru
13
Ohsumi, Yoshinori
10
Omori, Hiroko
10
Kabeya, Yukiko
10
Yamamoto, Akitsugu
8
Nara, Atsuki
7
Amano, Atsuo
4
Nakagawa, Ichiro
4
Ohsumi, Mariko
3
Sugamura, Kazuo
3
Umebayashi, Kyohei
3
Akira, Shizuo
3
Yamakami, Megumi
3
Kirisako, T
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All Publications
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2009: Noda Takeshi; Yoshimori Tamotsu
Molecular basis of canonical and bactericidal autophagy.
International immunology 2009;21(11):1199-204.
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2009: Taguwa Shuhei; Kambara Hiroto; Omori Hiroko; Tani Hideki; Abe Takayuki; Mori Yoshio; Suzuki Tetsuro; Yoshimori Tamotsu; Moriishi Kohji; Matsuura Yoshiharu
Cochaperone activity of human butyrate-induced transcript 1 facilitates hepatitis C virus replication through an Hsp90-dependent pathway.
Journal of virology 2009;83(20):10427-36.
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2009: Furuta Nobumichi; Tsuda Kayoko; Omori Hiroko; Yoshimori Tamotsu; Yoshimura Fuminobu; Amano Atsuo
Porphyromonas gingivalis outer membrane vesicles enter human epithelial cells via an endocytic pathway and are sorted to lysosomal compartments.
Infection and immunity 2009;77(10):4187-96.
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2009: Matsunaga Kohichi; Noda Takeshi; Yoshimori Tamotsu
Binding Rubicon to cross the Rubicon.
Autophagy 2009;5(6):876-7.
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2009: Noda T; Fujita N; Yoshimori T
The late stages of autophagy: how does the end begin?
Cell death and differentiation 2009;16(7):984-90.
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2009: Matsunaga Kohichi; Saitoh Tatsuya; Tabata Keisuke; Omori Hiroko; Satoh Takashi; Kurotori Naoki; Maejima Ikuko; Shirahama-Noda Kanae; Ichimura Tohru; Isobe Toshiaki; Akira Shizuo; Noda Takeshi; Yoshimori Tamotsu
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.
Nature cell biology 2009;11(4):385-96.
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2009: Terebiznik Mauricio R; Raju Deepa; Vázquez Cristina L; Torbricki Karl; Kulkarni Reshma; Blanke Steven R; Yoshimori Tamotsu; Colombo María I; Jones Nicola L
Effect of Helicobacter pylori's vacuolating cytotoxin on the autophagy pathway in gastric epithelial cells.
Autophagy 2009;5(3):370-9.
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2009: Fujita Naonobu; Noda Takeshi; Yoshimori Tamotsu
Atg4B(C74A) hampers autophagosome closure: a useful protein for inhibiting autophagy.
Autophagy 2009;5(1):88-9.
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2009: Yoshimori Tamotsu; Amano Atsuo
Group a streptococcus: a loser in the battle with autophagy.
Current topics in microbiology and immunology 2009;335():217-26.
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2009: Kimura Shunsuke; Fujita Naonobu; Noda Takeshi; Yoshimori Tamotsu
Monitoring autophagy in mammalian cultured cells through the dynamics of LC3.
Methods in enzymology 2009;452():1-12.
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2008: Saitoh Tatsuya; Fujita Naonobu; Jang Myoung Ho; Uematsu Satoshi; Yang Bo-Gie; Satoh Takashi; Omori Hiroko; Noda Takeshi; Yamamoto Naoki; Komatsu Masaaki; Tanaka Keiji; Kawai Taro; Tsujimura Tohru; Takeuchi Osamu; Yoshimori Tamotsu; Akira Shizuo
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.
Nature 2008;456(7219):264-8.
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2008: Fujita Naonobu; Hayashi-Nishino Mitsuko; Fukumoto Hiromi; Omori Hiroko; Yamamoto Akitsugu; Noda Takeshi; Yoshimori Tamotsu
An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.
Molecular biology of the cell 2008;19(11):4651-9.
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2008: Umebayashi Kyohei; Stenmark Harald; Yoshimori Tamotsu
Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation.
Molecular biology of the cell 2008;19(8):3454-62.
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2008: Yoshimori Tamotsu; Noda Takeshi
Toward unraveling membrane biogenesis in mammalian autophagy.
Current opinion in cell biology 2008;20(4):401-7.
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2008: Noda Takeshi; Fujita Naonobu; Yoshimori Tamotsu
The Ubi brothers reunited.
Autophagy 2008;4(4):540-1.
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2008: Fujita Naonobu; Itoh Takashi; Omori Hiroko; Fukuda Mitsunori; Noda Takeshi; Yoshimori Tamotsu
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy.
Molecular biology of the cell 2008;19(5):2092-100.
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2008: Okamoto Toru; Omori Hiroko; Kaname Yuuki; Abe Takayuki; Nishimura Yorihiro; Suzuki Tetsuro; Miyamura Tatsuo; Yoshimori Tamotsu; Moriishi Kohji; Matsuura Yoshiharu
A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replication.
Journal of virology 2008;82(7):3480-9.
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2008: Yoshimori Tamotsu
[Cellular defense by autophagy]
Gan to kagaku ryoho. Cancer & chemotherapy 2008;35(1):21-4.
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2008: Kimura Shunsuke; Noda Takeshi; Yoshimori Tamotsu
Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes.
Cell structure and function 2008;33(1):109-22.
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2008: Tsuda Kayoko; Furuta Nobumichi; Inaba Hiroaki; Kawai Shinji; Hanada Kentaro; Yoshimori Tamotsu; Amano Atsuo
Functional analysis of alpha5beta1 integrin and lipid rafts in invasion of epithelial cells by Porphyromonas gingivalis using fluorescent beads coated with bacterial membrane vesicles.
Cell structure and function 2008;33(1):123-32.
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2008: Fujibayashi Akemi; Taguchi Tomohiko; Misaki Ryo; Ohtani Masashi; Dohmae Naoshi; Takio Koji; Yamada Masashi; Gu Jianguo; Yamakami Megumi; Fukuda Mitsunori; Waguri Satoshi; Uchiyama Yasuo; Yoshimori Tamotsu; Sekiguchi Kiyotoshi
Human RME-8 is involved in membrane trafficking through early endosomes.
Cell structure and function 2008;33(1):35-50.
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2007: Uematsu Satoshi; Kaisho Tsuneyasu; Tanaka Takashi; Matsumoto Makoto; Yamakami Megumi; Omori Hiroko; Yamamoto Masahiro; Yoshimori Tamotsu; Akira Shizuo
The C/EBP beta isoform 34-kDa LAP is responsible for NF-IL-6-mediated gene induction in activated macrophages, but is not essential for intracellular bacteria killing.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5378-86.
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2007: Tamai Keiichi; Tanaka Nobuyuki; Nara Atsuki; Yamamoto Akitsugu; Nakagawa Ichiro; Yoshimori Tamotsu; Ueno Yoshiyuki; Shimosegawa Tooru; Sugamura Kazuo
Role of Hrs in maturation of autophagosomes in mammalian cells.
Biochemical and biophysical research communications 2007;360(4):721-7.
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2007: Birmingham Cheryl L; Canadien Veronica; Gouin Edith; Troy Erin B; Yoshimori Tamotsu; Cossart Pascale; Higgins Darren E; Brumell John H
Listeria monocytogenes evades killing by autophagy during colonization of host cells.
Autophagy 2007;3(5):442-51.
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2007: Kimura Shunsuke; Noda Takeshi; Yoshimori Tamotsu
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3.
Autophagy 2007;3(5):452-60.
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2007: Kato Takahiro; Tsuda Tetsuhisa; Omori Hiroko; Kato Takafumi; Yoshimori Tamotsu; Amano Atsuo
Maturation of fimbria precursor protein by exogenous gingipains in Porphyromonas gingivalis gingipain-null mutant.
FEMS microbiology letters 2007;273(1):96-102.
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2007: Yoshimori Tamotsu
Autophagy: paying Charon's toll.
Cell 2007;128(5):833-6.
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2007: Kato Takahiro; Kawai Shinji; Nakano Kazuhiko; Inaba Hiroaki; Kuboniwa Masae; Nakagawa Ichiro; Tsuda Kayoko; Omori Hiroko; Ooshima Takashi; Yoshimori Tamotsu; Amano Atsuo
Virulence of Porphyromonas gingivalis is altered by substitution of fimbria gene with different genotype.
Cellular microbiology 2007;9(3):753-65.
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2006: Amano Atsuo; Nakagawa Ichiro; Yoshimori Tamotsu
Autophagy in innate immunity against intracellular bacteria.
Journal of biochemistry 2006;140(2):161-6.
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2006: Kimura Shunsuke; Kamimoto Takahiro; Yoshimori Tamotsu
[Autophagic degradation of unfolding proteins]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2006;51(10 Suppl):1494-8.
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2006: Yoshimori Tamotsu
Autophagy vs. Group A Streptococcus.
Autophagy 2006;2(3):154-5.
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2006: Szeto Jason; Kaniuk Natalia A; Canadien Veronica; Nisman Rozalia; Mizushima Noboru; Yoshimori Tamotsu; Bazett-Jones David P; Brumell John H
ALIS are stress-induced protein storage compartments for substrates of the proteasome and autophagy.
Autophagy 2006;2(3):189-99.
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2006: Nakashima Akitoshi; Tanaka Nobuyuki; Tamai Keiichi; Kyuuma Masanao; Ishikawa Yoshinori; Sato Hiroyuki; Yoshimori Tamotsu; Saito Shigeru; Sugamura Kazuo
Survival of parvovirus B19-infected cells by cellular autophagy.
Virology 2006;349(2):254-63.
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2006: Birmingham Cheryl L; Smith Adam C; Bakowski Malina A; Yoshimori Tamotsu; Brumell John H
Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole.
The Journal of biological chemistry 2006;281(16):11374-83.
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2006: Shim Jae-Hyuck; Xiao Changchun; Hayden Matthew S; Lee Ki-Young; Trombetta E Sergio; Pypaert Marc; Nara Atsuki; Yoshimori Tamotsu; Wilm Bettina; Erdjument-Bromage Hediye; Tempst Paul; Hogan Brigid L M; Mellman Ira; Ghosh Sankar
CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis.
The Journal of cell biology 2006;172(7):1045-56.
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2006: Kamimoto Takahiro; Shoji Shisako; Hidvegi Tunda; Mizushima Noboru; Umebayashi Kyohei; Perlmutter David H; Yoshimori Tamotsu
Intracellular inclusions containing mutant alpha1-antitrypsin Z are propagated in the absence of autophagic activity.
The Journal of biological chemistry 2006;281(7):4467-76.
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2005: Towns Roberto; Kabeya Yukiko; Yoshimori Tamotsu; Guo Chunfang; Shangguan Yu; Hong Shuangsong; Kaplan Mariana; Klionsky Daniel J; Wiley John W
Sera from patients with type 2 diabetes and neuropathy induce autophagy and colocalization with mitochondria in SY5Y cells.
Autophagy 2005;1(3):163-70.
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2005: Yamada Takahiro; Carson Andrew R; Caniggia Isabella; Umebayashi Kyohei; Yoshimori Tamotsu; Nakabayashi Kazuhiko; Scherer Stephen W
Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast.
The Journal of biological chemistry 2005;280(18):18283-90.
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2005: Tsuda Kayoko; Amano Atsuo; Umebayashi Kyohei; Inaba Hiroaki; Nakagawa Ichiro; Nakanishi Yoshinobu; Yoshimori Tamotsu
Molecular dissection of internalization of Porphyromonas gingivalis by cells using fluorescent beads coated with bacterial membrane vesicle.
Cell structure and function 2005;30(2):81-91.
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2004: Nakagawa Ichiro; Amano Atsuo; Mizushima Noboru; Yamamoto Akitsugu; Yamaguchi Hitomi; Kamimoto Takahiro; Nara Atsuki; Funao Junko; Nakata Masanobu; Tsuda Kayoko; Hamada Shigeyuki; Yoshimori Tamotsu
Autophagy defends cells against invading group A Streptococcus.
Science (New York, N.Y.) 2004;306(5698):1037-40.
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2004: Fujita Hideaki; Umezuki Yusuke; Imamura Kanako; Ishikawa Daisuke; Uchimura Seiko; Nara Atsuki; Yoshimori Tamotsu; Hayashizaki Yoshihide; Kawai Jun; Ishidoh Kazumi; Tanaka Yoshitaka; Himeno Masaru
Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B.
Journal of cell science 2004;117(Pt 14):2997-3009.
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2004: Kabeya Yukiko; Mizushima Noboru; Yamamoto Akitsugu; Oshitani-Okamoto Satsuki; Ohsumi Yoshinori; Yoshimori Tamotsu
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation.
Journal of cell science 2004;117(Pt 13):2805-12.
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2004: Mizushima Noboru; Yamamoto Akitsugu; Matsui Makoto; Yoshimori Tamotsu; Ohsumi Yoshinori
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker.
Molecular biology of the cell 2004;15(3):1101-11.
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2004: Yoshimori Tamotsu
Autophagy: a regulated bulk degradation process inside cells.
Biochemical and biophysical research communications 2004;313(2):453-8.
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2003: Yamakami Megumi; Yoshimori Tamotsu; Yokosawa Hideyoshi
Tom1, a VHS domain-containing protein, interacts with tollip, ubiquitin, and clathrin.
The Journal of biological chemistry 2003;278(52):52865-72.
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2003: Saeki Kumiko; Hong Zhang; Nakatsu Masami; Yoshimori Tamotsu; Kabeya Yukiko; Yamamoto Akitsugu; Kaburagi Yasushi; Yuo Akira
Insulin-dependent signaling regulates azurophil granule-selective macroautophagy in human myeloblastic cells.
Journal of leukocyte biology 2003;74(6):1108-16.
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2003: Kanazawa Chikako; Morita Eiji; Yamada Mitsuhiro; Ishii Naoto; Miura Shigeta; Asao Hironobu; Yoshimori Tamostu; Sugamura Kazuo
Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation.
Biochemical and biophysical research communications 2003;309(4):848-56.
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2003: Katoh Keiichi; Shibata Hideki; Suzuki Hidenori; Nara Atsuki; Ishidoh Kazumi; Kominami Eiki; Yoshimori Tamotsu; Maki Masatoshi
The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting.
The Journal of biological chemistry 2003;278(40):39104-13.
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2003: Ohashi Masato; Mizushima Noboru; Kabeya Yukiko; Yoshimori Tamotsu
Localization of mammalian NAD(P)H steroid dehydrogenase-like protein on lipid droplets.
The Journal of biological chemistry 2003;278(38):36819-29.
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2003: Fujita Hideaki; Yamanaka Motoko; Imamura Kanako; Tanaka Yoshitaka; Nara Atsuki; Yoshimori Tamotsu; Yokota Sadaki; Himeno Masaru
A dominant negative form of the AAA ATPase SKD1/VPS4 impairs membrane trafficking out of endosomal/lysosomal compartments: class E vps phenotype in mammalian cells.
Journal of cell science 2003;116(Pt 2):401-14.
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2002: Mizushima Noboru; Ohsumi Yoshinori; Yoshimori Tamotsu
Autophagosome formation in mammalian cells.
Cell structure and function 2002;27(6):421-9.
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2002: Yoshimori Tamotsu
Toward and beyond lysosomes.
Cell structure and function 2002;27(6):401-2.
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2002: Nara Atsuki; Mizushima Noboru; Yamamoto Akitsugu; Kabeya Yukiko; Ohsumi Yoshinori; Yoshimori Tamotsu
SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation.
Cell structure and function 2002;27(1):29-37.
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2001: Ishihara N; Hamasaki M; Yokota S; Suzuki K; Kamada Y; Kihara A; Yoshimori T; Noda T; Ohsumi Y
Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion.
Molecular biology of the cell 2001;12(11):3690-702.
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2001: Yoshimori T
[Autophagy in mammalian cells--enter actors]
Seikagaku. The Journal of Japanese Biochemical Society 2001;73(9):1154-9.
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2001: Kihara A; Kabeya Y; Ohsumi Y; Yoshimori T
Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network.
EMBO reports 2001;2(4):330-5.
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2001: Mizushima N; Yamamoto A; Hatano M; Kobayashi Y; Kabeya Y; Suzuki K; Tokuhisa T; Ohsumi Y; Yoshimori T
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells.
The Journal of cell biology 2001;152(4):657-68.
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2000: Kabeya Y; Mizushima N; Ueno T; Yamamoto A; Kirisako T; Noda T; Kominami E; Ohsumi Y; Yoshimori T
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing.
The EMBO journal 2000;19(21):5720-8.
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2000: Kirisako T; Ichimura Y; Okada H; Kabeya Y; Mizushima N; Yoshimori T; Ohsumi M; Takao T; Noda T; Ohsumi Y
The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway.
The Journal of cell biology 2000;151(2):263-76.
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2000: Yoshimori T; Yamagata F; Yamamoto A; Mizushima N; Kabeya Y; Nara A; Miwako I; Ohashi M; Ohsumi M; Ohsumi Y
The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cells.
Molecular biology of the cell 2000;11(2):747-63.
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1999: Kirisako T; Baba M; Ishihara N; Miyazawa K; Ohsumi M; Yoshimori T; Noda T; Ohsumi Y
Formation process of autophagosome is traced with Apg8/Aut7p in yeast.
The Journal of cell biology 1999;147(2):435-46.
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1998: Mizushima N; Sugita H; Yoshimori T; Ohsumi Y
A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy.
The Journal of biological chemistry 1998;273(51):33889-92.
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1998: Mizushima N; Noda T; Yoshimori T; Tanaka Y; Ishii T; George M D; Klionsky D J; Ohsumi M; Ohsumi Y
A protein conjugation system essential for autophagy.
Nature 1998;395(6700):395-8.
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1997: Yoshimori T
[Sorting in the TGN into different transport routes to the plasma membrane in fibroblasts]
Seikagaku. The Journal of Japanese Biochemical Society 1997;69(6):410-6.
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