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Josef Brock

Research Profile

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Chemicals & Drugs

Anatomy

T-Lymphocytes

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Hermann Walzel; Abdelgawad A Fahmi; Mohamed A Eldesouky; ehab Fathy aboueladab; Grit Waitz; Josef Brock; Markus Tiedge
Effects of N-glycan processing inhibitors on signaling events and induction of apoptosis in galectin-1-stimulated Jurkat T lymphocytes.
Tom Büchse; Holger Prietzsch; Tilo Sasse; Sandra Körbel; Gunnar Stigge; Simon Bogdanow; Josef Brock; Thomas Bittorf
Profiling of early gene expression induced by erythropoietin receptor structural variants.
Sandra Körbel; Tom Büchse; Holger Prietzsch; Tilo Sasse; Michael Schümann; Eberhard Krause; Josef Brock; Thomas Bittorf
Phosphoprotein profiling of erythropoietin receptor- dependent pathways using different proteomic strategies.

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2006: Hermann Walzel; Abdelgawad A Fahmi; Mohamed A Eldesouky; ehab Fathy aboueladab; Grit Waitz; Josef Brock; Markus Tiedge
Effects of N-glycan processing inhibitors on signaling events and induction of apoptosis in galectin-1-stimulated Jurkat T lymphocytes.
Glycobiology 2006;16(12):1262-71.
2006: Tom Büchse; Holger Prietzsch; Tilo Sasse; Sandra Körbel; Gunnar Stigge; Simon Bogdanow; Josef Brock; Thomas Bittorf
Profiling of early gene expression induced by erythropoietin receptor structural variants.
The Journal of biological chemistry 2006;281(12):7697-707.
2005: Sandra Körbel; Tom Büchse; Holger Prietzsch; Tilo Sasse; Michael Schümann; Eberhard Krause; Josef Brock; Thomas Bittorf
Phosphoprotein profiling of erythropoietin receptor- dependent pathways using different proteomic strategies.
Proteomics 2005;5(1):91-100.
2004: Hermann Walzel; Josef Brock; Ralf Pöhland; Jens Vanselow; Wolfgang Tomek; Falk Schneider; Ute Tiemann
Effects of galectin-1 on regulation of progesterone production in granulosa cells from pig ovaries in vitro.
Glycobiology 2004;14(10):871-81.
2004: Grit Schroeder; Kirsten Risch; Katja Kotsch; Anja Siepert; Josef Brock; Peter Nickel; Petra Reinke; Thomas Ritter; Hans-Dieter Volk; Manfred Lehmann
FTY720 prevents anti-CD4 mAb-induced tolerance but cannot reverse established tolerance in a rat kidney transplantation model.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4(6):863-71.
2002: Hermann Walzel; Matthias Blach; Jun Hirabayashi; Yoichiro Arata; Ken-ichi Kasai; Josef Brock
Galectin-induced activation of the transcription factors NFAT and AP-1 in human Jurkat T-lymphocytes.
Cellular signalling 2002;14(10):861-8.
2002: Holger Prietzsch; Josef Brock; Hans-Dieter Kleine; Stefan Liebe; Robert Jaster
Interferon-alpha inhibits cell cycle progression by Ba/F3 cells through the antagonisation of interleukin-3 effects on key regulators of G(1)/S transition.
Cellular signalling 2002;14(9):751-9.
2002: Birgit Sawitzki; Manfred Lehmann; Katrin Vogt; Martina Seifert; Kirsten Risch; Josef Brock; Jerzy W Kupiec-Weglinski; Hans-Dieter Volk
Bag-1 up-regulation in anti-CD4 mAb-treated allo-activated T cell confers resistance to activation-induced cell death (AICD).
Transplant immunology 2002;9(2-4):83-91.
2002: Birgit Sawitzki; Manfred Lehmann; Katrin Vogt; Kirsten Risch; Josef Brock; Jerzy W Kupiec-Weglinski; Hans-Dieter Volk
Bag-1 up-regulation in anti-CD4 mAb treated allo-activated T cells confers resistance to apoptosis.
European journal of immunology 2002;32(3):800-9.
2001: Hermann Walzel; Matthias Blach; P Neels; U Schulz; Karin Wollenhaupt; Josef Brock
The B-chain of mistletoe lectin I efficiently stimulates calcium signaling in human Jurkat T-cells.
Immunology letters 2001;78(2):57-66.
2001: Thomas Bittorf; Tom Büchse; Tilo Sasse; Robert Jaster; Josef Brock
Activation of the transcription factor NF-kappaB by the erythropoietin receptor: structural requirements and biological significance.
Cellular signalling 2001;13(9):673-81.
2001: Grit Schröder; M Hammer; Kirsten Risch; Alexander Flügel; Josef Brock; Manfred Lehmann; Thomas Ritter; Hans-Dieter Volk
Visualization of alloantigen-specific, EGFP-engineered T lymphocytes in a rat kidney transplantation model.
Transplantation proceedings 2001;33(1-2):607-8.
2001: Kirsten Risch; H P Strebel; R K Joshi; Jens Lutz; Josef Brock; Khusru Asadullah; Hans-Dieter Volk; Manfred Lehmann
Methyl hydrogen fumarate inhibits acute and chronic rejection in rat kidney transplantation models.
Transplantation proceedings 2001;33(1-2):545-6.
2000: Renate Claus; Thomas Bittorf; Hermann Walzel; Josef Brock; R Uhde; Doris Meiske; U Schulz; D Hobusch; K Schumacher; M Witt; F Bartel; S Hausmann
High concentration of soluble HLA-DR in the synovial fluid: generation and significance in "rheumatoid-like" inflammatory joint diseases.
Cellular immunology 2000;206(2):85-100.
2000: Thomas Bittorf; Tilo Sasse; M Wright; Robert Jaster; Livia Otte; Jens Schneider-Mergener; Josef Brock
cDNA cloning and functional analysis of a truncated STAT5a protein from autonomously growing FDCP-1 cells.
Cellular signalling 2000;12(11-12):721-30.
2000: Thomas Bittorf; Robert Jaster; M J Soares; J Seiler; Josef Brock; Klaus Friese; Heiner Müller
Induction of erythroid proliferation and differentiation by a trophoblast-specific cytokine involves activation of the JAK/STAT pathway.
Journal of molecular endocrinology 2000;25(2):253-62.
2000: Grit Schröder; Kirsten Risch; Horst Nizze; J Kolls; Petra Reinke; Josef Brock; Manfred Lehmann; Hans-Dieter Volk; Thomas Ritter
Immune response after adenoviral gene transfer in syngeneic heart transplants: effects of anti-CD4 monoclonal antibody therapy.
Transplantation 2000;70(1):191-8.
2000: Hermann Walzel; Matthias Blach; J Hirabayashi; K I Kasai; Josef Brock
Involvement of CD2 and CD3 in galectin-1 induced signaling in human Jurkat T-cells.
Glycobiology 2000;10(2):131-40.
2000: J Heinig; S Wilhelm; H Müller; Volker Briese; Thomas Bittorf; Josef Brock
Determination of cytokine mRNA-expression in term human placenta of patients with gestational hypertension, intrauterine growth retardation and gestational diabetes mellitus using polymerase chain reaction.
Zentralblatt für Gynäkologie 2000;122(8):413-8.
2000: Thomas Bittorf; J Seiler; B Lüdtke; Tom Büchse; Robert Jaster; Josef Brock
Activation of STAT5 during EPO-directed suppression of apoptosis.
Cellular signalling 2000;12(1):23-30.
1999: Thomas Ritter; Kirsten Risch; G Schroder; J Kolls; A Siegling; E Graser; Petra Reinke; Josef Brock; Manfred Lehmann; Hans-Dieter Volk
Intragraft overexpression of interleukin-4 is neither sufficient nor essential for tolerance induction to cardiac allografts in a high-responder strain combination.
Transplantation 1999;68(9):1427-31.
1999: Thomas Bittorf; J Seiler; Z Zhang; Robert Jaster; Josef Brock
SHP1 protein tyrosine phosphatase negatively modulates erythroid differentiation and suppression of apoptosis in J2E erythroleukemic cells.
Biological chemistry 1999;380(10):1201-9.
1999: Robert Jaster; E Tschirch; Thomas Bittorf; Josef Brock
Interferon-alpha inhibits proliferation of Ba/F3 cells by interfering with interleukin-3 action.
Cellular signalling 1999;11(10):769-75.
1999: Robert Jaster; E Tschirch; Thomas Bittorf; Josef Brock
Role of STAT5 in interferon-alpha signal transduction in Ba/F3 cells.
Cellular signalling 1999;11(5):331-5.
1999: Hermann Walzel; U Schulz; P Neels; Josef Brock
Galectin-1, a natural ligand for the receptor-type protein tyrosine phosphatase CD45.
Immunology letters 1999;67(3):193-202.
1999: Manfred Lehmann; Kirsten Risch; Horst Nizze; G Brandenburg; Thomas Ritter; Josef Brock; Hans-Dieter Volk
Abolition of anti-CD4-induced allotransplantation tolerance by exogenous IL-2.
Transplantation proceedings 1999;31(1-2):1220-1.
1999: Thomas Ritter; Martina Seifert; Kirsten Risch; A Fretz; H Tanzmann; Josef Brock; Hans-Dieter Volk; Manfred Lehmann
Depletion of IL-4 does not prevent tolerance induction in an allogeneic rat kidney transplantation model.
Transplantation proceedings 1999;31(1-2):887-8.
1999: Beate Kuttler; K Rösing; Manfred Lehmann; Josef Brock; Hans-Jürgen Hahn
Prevention of autoimmune but not allogeneic destruction of grafted islets by different therapeutic strategies.
Journal of molecular medicine (Berlin, Germany) 1999;77(1):226-9.
1998: Tilo Sasse; P Becker; P Dorfling; T Schuhr; Josef Brock
TGF beta-1 mRNA expression and proliferation of human osteoblastic cells in nonosteoporotic and osteoporotic women under influence of TGF beta-1 and IGF-I.
Calcified tissue international 1998;62(2):140-7.
1997: Manfred Lehmann; E Graser; Kirsten Risch; W W Hancock; A Müller; Beate Kuttler; Hans-Jürgen Hahn; Jerzy W Kupiec-Weglinski; Josef Brock; Hans-Dieter Volk
Anti-CD4 monoclonal antibody-induced allograft tolerance in rats despite persistence of donor-reactive T cells.
Transplantation 1997;64(8):1181-7.
1997: O Arndt; A Johannes; K Zeise; Josef Brock
[High-risk HPV types in oral and laryngeal papilloma and leukoplakia].
Laryngo- rhino- otologie 1997;76(3):142-9.
1997: E Graser; Kirsten Risch; Peter Linsley; W W Hancock; A Müller; Josef Brock; Petra Reinke; Jerzy W Kupiec-Weglinski; Hans-Dieter Volk; Manfred Lehmann
Synergism of CTLA4-IG and anti-CD4 monoclonal antibody treatment in a rat kidney transplant model.
Transplantation proceedings 1997;29(1-2):1307-9.
1997: Kirsten Risch; G Becker; E Graser; Horst Nizze; Josef Brock; Hans-Dieter Volk; Uwe Heemann; Manfred Lehmann
Inhibition of chronic rejection after kidney transplantation by anti-CD4 treatment.
Transplantation proceedings 1997;29(1-2):328-9.
1997: Robert Jaster; Thomas Bittorf; Josef Brock
Involvement of phosphatidylinositol 3-kinase in the mediation of erythropoietin-induced activation of p70S6k.
Cellular signalling 1997;9(2):175-9.
1997: Thomas Bittorf; Robert Jaster; B Lüdtke; B Kamper; Josef Brock
Requirement for JAK2 in erythropoietin-induced signalling pathways.
Cellular signalling 1997;9(1):85-9.
1996: Robert Jaster; Thomas Bittorf; S Peter Klinken; Josef Brock
Inhibition of proliferation but not erythroid differentiation of J2E cells by rapamycin.
Biochemical pharmacology 1996;51(9):1181-5.
1996: Kirsten Risch; U Heemann; E Graser; Barbara Nebe; Horst Nizze; J Lacha; Josef Brock; Hans-Dieter Volk; Manfred Lehmann
Assessment of chronic rejection in permanent accepted renal allografts in anti-CD4 treated rats.
Clinical nephrology 1996;45(5):358-60.
1996: Hermann Walzel; J Hirabayashi; K Kasai; Josef Brock; P Neels
Cell calcium signalling induced by endogenous lectin carbohydrate interaction in the Jurkat T cell line.
Glycoconjugate journal 1996;13(1):99-105.
1995: Robert Jaster; Thomas Bittorf; M Markewitz; G Selig; Josef Brock
Erythropoietin induces biphasic activation of p70S6k: evidence for a different regulation of early and late phase of activation.
Cellular signalling 1995;7(4):325-30.
1995: J Altrichter; A H Guse; K Resch; Josef Brock; Marc Daëron; C Hückel
Phosphatidylinositol hydrolysis and an increase in Ca2+ concentration in the signal-transduction process triggered by murine Fc gamma RIII are not required for protein kinase C translocation.
European journal of biochemistry / FEBS 1995;228(3):587-95.
1995: Manfred Lehmann; J Havlickova; Kirsten Risch; K Pulya; J Lacha; Josef Brock; Hans-Dieter Volk
Role of the spleen in the establishment and maintenance of anti-CD4-induced transplant nonresponsiveness.
Transplantation proceedings 1995;27(1):121-2.
1995: Hermann Walzel; P Neels; H Bremer; H Köhler; N Raab; M Barten; Josef Brock
Immunohistochemical and glycohistochemical localization of the beta-galactoside-binding S-type lectin in human placenta.
Acta histochemica 1995;97(1):33-42.
1994: Hans-Dieter Volk; A Siegling; Cornelia Platzer; Josef Brock; Frank Emmrich; Manfred Lehmann
Tolerance induction by anti-CD4 MAb treatment in a rat kidney transplantation model.
Transplantation proceedings 1994;26(6):3155-6.
1994: O Arndt; K Nottelmann; Josef Brock; O G Neumann
[Inverted papilloma and its association with human papillomavirus (HPV). A study with polymerase chain reaction (PCR)].
HNO 1994;42(11):670-6.
1994: O Arndt; Josef Brock; G Kundt; A Müllender
[Detection of human papillomavirus DNA in formalin fixed invasive squamous cell carcinoma of the larynx with polymerase chain reaction (PCR)].
Laryngo- rhino- otologie 1994;73(10):527-32.
1994: Beate Kuttler; Manfred Lehmann; J Lacha; Josef Brock; Hans-Jürgen Hahn
Anti-CD4 therapy induces a donor-specific, organ-nonspecific tolerance in allogeneic kidney graft recipients.
Transplantation proceedings 1994;26(2):728-9.
1994: Thomas Bittorf; Robert Jaster; Josef Brock
Rapid activation of the MAP kinase pathway in hematopoietic cells by erythropoietin, granulocyte-macrophage colony-stimulating factor and interleukin-3.
Cellular signalling 1994;6(3):305-11.
1994: A Siegling; Manfred Lehmann; H Riedel; Cornelia Platzer; Josef Brock; Frank Emmrich; Hans-Dieter Volk
A nondepleting anti-rat CD4 monoclonal antibody that suppresses T helper 1-like but not T helper 2-like intragraft lymphokine secretion induces long-term survival of renal allografts.
Transplantation 1994;57(3):464-7.
1993: Thomas Bittorf; Robert Jaster; Josef Brock
Structural and functional characterisation of recombinant human erythropoietin analogues.
FEBS letters 1993;336(1):133-6.
1993: Manfred Lehmann; Beate Kuttler; A Siegling; A Gordalla; H Riedel; J Lacha; Hans-Jürgen Hahn; Josef Brock; Hans-Dieter Volk
Characterization of the anti-CD4-induced permanent acceptance of rat renal allografts.
Transplantation proceedings 1993;25(5):2859-60.
1993: O Arndt; K Zeise; J Bauer; Josef Brock
[Correlation between chronic hyperplastic laryngitis and infection with human papillomaviruses].
HNO 1993;41(3):123-7.
1993: J Heinig; S Wilhelm; Thomas Bittorf; H Müller; Josef Brock; Volker Briese
Semiquantitative determination of IL-1 alpha, TNF-alpha, PDGF-A, PDGF-B, and PDGF-receptor in term human placenta using polymerase chain reaction (PCR).
Zentralblatt für Gynäkologie 1993;115(7):317-22.
1992: Manfred Lehmann; F Sternkopf; F Metz; Josef Brock; W D Döcke; A Plantikow; Beate Kuttler; Hans-Jürgen Hahn; B Ringel; Hans-Dieter Volk
Induction of long-term survival of rat skin allografts by a novel, highly efficient anti-CD4 monoclonal antibody.
Transplantation 1992;54(6):959-62.
1992: O Arndt; K Zeise; I Bauer; Josef Brock
[Type 6/11 and 16/18 squamous epithelial cancers of the upper respiratory tract and digestive system. An in situ hybridization study].
Laryngo- rhino- otologie 1992;71(10):500-4.
1992: O Arndt; K Zeise; I Bauer; Josef Brock
[Detection of human papillomaviruses (HPV) in laryngeal papilloma. An in situ hybridization study].
Laryngo- rhino- otologie 1992;71(3):132-6.
1991: O Arndt; I Bauer; Josef Brock
[Use of the Dot-Blot technique in the detection of human papillomavirus(HPV) deoxyribonucleic acid (DNA) in malignant tumors of the oropharynx].
Laryngo- rhino- otologie 1991;70(8):441-4.
1991: Josef Brock; H A Schulze; P Neels; A Fischer; H Bremer; Hermann Walzel
Detection of mannose-binding proteins on mouse lymphocytes.
European journal of cell biology 1991;54(1):90-4.
1991: M Lehmann; Beate Kuttler; H Köhler; Hans-Jürgen Hahn; H D Volk; Josef Brock
The monoclonal antibody RIB5/1--a useful completion of the MRC OX-3 and OX-6 haplotype specificity.
Folia biologica 1991;37(1):55-9.
1991: J Hein; E Martens; I Bauer; P Dörfling; Josef Brock; H U Gülzow; K Breuel; I Rudolph
[Bronchoalveolar lavage--a diagnostic method in chronic nonspecific bronchopulmonary diseases in childhood? 2. Studies of cellular and humoral parameters in BAL irrigation fluid].
Zeitschrift für Erkrankungen der Atmungsorgane 1991;176(1):7-20.
1991: Hermann Walzel; H Bremer; P Neels; Ludwig Jonas; Josef Brock
Preparation of a neoglycoprotein using a homobifunctional reagent and its applicability for protein blotting and electron microscopy.
Biomedica biochimica acta 1991;50(2):151-7.
1990: Hermann Walzel; Ludwig Jonas; T Rosin; Josef Brock
Relationship between internalization kinetics and cytotoxicity of mistletoe lectin I to L1210 leukaemia cells.
Folia biologica 1990;36(3-4):181-8.
1990: J Hein; E Knippel; W Schütt; U Lenschow; H U Gülzow; K Breuel; I Bauer; Thomas Bittorf; Josef Brock
Diagnosis of cystic fibrosis by means of particle electrophoresis test.
Acta Universitatis Carolinae. Medica 1990;36(1-4):62-4.
1990: J Hein; M Seyfarth; Josef Brock; H D Kirschnick; S Schober; K Breuel; H U Gülzow
Secretory immunoglobulin A in serum of CF patients.
Acta Universitatis Carolinae. Medica 1990;36(1-4):169-70.
1990: J Gedschold; R Brückner; Reinhard Szibor; V Steinbicker; W Berger; K Grade; C Coutelle; I Bauer; Thomas Bittorf; Josef Brock
Distribution of RFLP haplotypes in CF in relation to clinical course.
Acta Universitatis Carolinae. Medica 1990;36(1-4):115-6.
1989: Hermann Walzel; Josef Brock; H Franz; P Ziska
Detection and quantification of ligand leakage from lectin affinity columns.
Biomedica biochimica acta 1989;48(4):221-6.
1988: C Huckel; M Sandor; H L Jenssen; Joachim Rychly; Josef Brock; J Gergely
The binding of IgG1 containing immune complexes to the FcR of allogenically activated T cells induces changes in the membrane potential and the cell surface charge.
Molecular immunology 1988;25(6):517-25.
1988: J Hein; S Schober; M Seyfarth; Josef Brock; H D Kirschnick
Secretory immunoglobulin A (sIgA) in the serum of cystic fibrosis patients.
Wiener klinische Wochenschrift 1988;100(2):57-9.
1988: C Hückel; P Kusnierczyk; E Pajtasz; Josef Brock
[Functional capacity of T-cell subpopulations of the mouse. Effect of unstimulated and allogenic stimulated T-cell subpopulations on Con A stimulation of splenic lymphocytes].
Allergie und Immunologie 1988;34(1):27-34.
1988: C Hückel; H L Jenssen; Eilhard Mix; P Kusnierczyk; E Pajtasz; Josef Brock
[The binding behavior and functional significance of Fc receptors for IgG on T lymphocytes of the mouse].
Allergie und Immunologie 1988;34(2):109-18.
1988: C Hückel; P Kusnierszyk; E Pajtasz; H A Schulze; Josef Brock
[Functional capacity of T cell subpopulations in mice. II. Effect of allogeneically stimulated T-cell subpopulations on the primary MLR].
Allergie und Immunologie 1988;34(3):159-67.
1987: M Seyfarth; Josef Brock; H Fiebig; J Edelmann; B Seidel
[Importance of secretory IgA in human body fluids. I. Development of an enzyme immunoassay for secretory IgA].
Allergie und Immunologie 1987;33(3):147-52.
1987: C Hückel; P Kusnierczyk; H L Jenssen; E Pajtasz; Josef Brock
[Relations between concanavalin A binding and cell proliferation. Comparison of Lyt-1+ and Lyt-2+ lymphocyte subpopulations from the spleen of unstimulated mice and mixed lymphocyte culture].
Allergie und Immunologie 1987;33(2):71-8.
1987: C Hückel; P Kusnierczyk; E Pajtasz; Josef Brock
Suppression of cell proliferation after incubation of allogeneically stimulated mouse lymphocytes with concanavalin A: serological analysis of cell subpopulations involved.
Folia biologica 1987;33(3):191-9.
1986: C Hückel; M Sandor; A Erdei; H L Jensen; Josef Brock; Joachim Rychly; J Gergely
[Comparative studies of Fc receptors for IgG on resting and activated mouse T lymphocytes using different methods].
Allergie und Immunologie 1986;32(1):47-56.
1985: J Hein; I Bauer; H Bremer; Josef Brock
[Lymphocytic adenosine deaminase activity in children with acute and chronic respiratory tract diseases].
Kinderärztliche Praxis 1985;53(10):499-505.
1985: C Hückel; Josef Brock; Joachim Rychly; U Schulz; H A Schulze
Qualitative and quantitative Con A binding to mouse lymphocytes, T cell enriched spleen cells and allogeneically stimulated lymphocytes.
Archivum immunologiae et therapiae experimentalis 1985;33(5):645-57.
1981: H Bremer; I Bauer; Josef Brock
[Adenosine deaminase activity and immune dysfunction (author's transl)].
Allergie und Immunologie 1981;27(1):3-13.