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Ming You

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TOP 3
Yian Wang; Weidong Wen; Ruisheng Yao; Yinqiu Du; Song Gao; Ming Hu; Ronald A Lubet; Eva Szabo; Ming You
Chemopreventive effect of a mixture of Chinese Herbs (antitumor B) on chemically induced oral carcinogenesis.
Haris G Vikis; Jihong Zhu; Andrew Franklin; Andrew E Gelman; Alexander S Krupnick; Pengyuan Liu; Amy Rymaszewski; Lauren Stein; Jay W Tichelaar; Ming You
Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis.
Ramaswamy Govindan; Malachi Griffith; Krishna L Kanchi; Christopher A Maher; Elaine R Mardis; Sandra McDonald; David Ornitz; Janakiraman Subramanian; Jason Walker; John Wallis; Mark Watson; Ron Bose; Ken Chen; Nathan D Dees; Li Ding; David J Dooling; Lucinda Fulton; Robert Fulton; Donghai Xiong; Ming You; Richard K Wilson
Genomic landscape of non-small cell lung cancer in smokers and never-smokers.

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All Publications

2013: Yian Wang; Weidong Wen; Ruisheng Yao; Yinqiu Du; Song Gao; Ming Hu; Ronald A Lubet; Eva Szabo; Ming You
Chemopreventive effect of a mixture of Chinese Herbs (antitumor B) on chemically induced oral carcinogenesis.
Molecular carcinogenesis 2013;52(1):49-56.
2012: Haris G Vikis; Jihong Zhu; Andrew Franklin; Andrew E Gelman; Alexander S Krupnick; Pengyuan Liu; Amy Rymaszewski; Lauren Stein; Jay W Tichelaar; Ming You
Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis.
Molecular carcinogenesis 2012;51(12):993-1002.
2012: Ramaswamy Govindan; Malachi Griffith; Krishna L Kanchi; Christopher A Maher; Elaine R Mardis; Sandra McDonald; David Ornitz; Janakiraman Subramanian; Jason Walker; John Wallis; Mark Watson; Ron Bose; Ken Chen; Nathan D Dees; Li Ding; David J Dooling; Lucinda Fulton; Robert Fulton; Donghai Xiong; Ming You; Richard K Wilson
Genomic landscape of non-small cell lung cancer in smokers and never-smokers.
Cell 2012;150(6):1121-34.
2012: Daniel Kreisel; Jack D Bui; Beatriz M Carreno; Charuhas Deshpande; Andrew E Gelman; Ryuji Higashikubo; Xue Lin; Robert D Schreiber; Samantha M Taffner; Kelsey A Toth; Haris G Vikis; J Michael White; Wayne M Yokoyama; Ming You; Alexander S Krupnick
Strain-specific variation in murine natural killer gene complex contributes to differences in immunosurveillance for urethane-induced lung cancer.
Cancer research 2012;72(17):4311-7.
2012: Yan Lu; John Pfeifer; Ananth Sezhiyan; Liang Wang; Yian Wang; Weidong Wen; Ping Yang; Boone Goodgame; Ramaswamy Govindan; Xing Hua; Ya-fei Li; Peng-yuan Liu; Ming You
MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer.
Carcinogenesis 2012;33(5):1046-54.
2012: Yian Wang; Ming You; Lucina Rouggly; Ronald Lubet
Animal models of lung cancer characterization and use for chemoprevention research.
Progress in molecular biology and translational science 2012;105():211-26.
2011: Huijing Fu; Yan Lu; Ronald A Lubet; Jing Pan; Eva Szabo; Yian Wang; Weidong Wen; Da-Ren Chen; Ruth Chen; Jingjie Zhang; Qi Zhang; Ming You
Chemoprevention of lung carcinogenesis by the combination of aerosolized budesonide and oral pioglitazone in A/J mice.
Molecular carcinogenesis 2011;50(12):913-21.
2011: Ronald A Lubet; Yan Lu; Ann M Bode; Ming You; Zoe M Verney; Vernon E Steele; Reid Townsend; M Margaret Juliana; Clinton J Grubbs
Efficacy of the EGFr inhibitor Iressa on development of chemically-induced urinary bladder cancers: dose dependency and modulation of biomarkers.
Oncology reports 2011;25(5):1389-97.
2011: H Chen; Ming You; Yunfang Jiang; Wei Wang; Li Li
RMI1 attenuates tumor development and is essential for early embryonic survival.
Molecular carcinogenesis 2011;50(2):80-8.
2011: Qi Zhang; Jing Pan; Jingjie Zhang; Pengyuan Liu; Ruth Chen; Da-ren Chen; Ronald Lubet; Yian Wang; Ming You
Aerosolized bexarotene inhibits lung tumorigenesis without increasing plasma triglyceride and cholesterol levels in mice.
Cancer prevention research (Philadelphia, Pa.) 2011;4(2):270-6.
2011: Michael A James; Huijing Fu; Yan Liu; Da-Ren Chen; Ming You
Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis.
Molecular carcinogenesis 2011;50(1):1-7.
2010: Shenying Fang; Susan Pinney; Joan E Bailey-Wilson; Mariza de Andrade; Yafang Li; Elena Kupert; Ming You; Ann Grossbart Schwartz; Ping Yang; Marshall W Anderson; Christopher I Amos
Ordered subset analysis identifies loci influencing lung cancer risk on chromosomes 6q and 12q.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010;19(12):3157-66.
2010: Yian Wang; Michael James; Weidong Wen; Yan Lu; Eva Szabo; Ronald A Lubet; Ming You
Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice.
Molecular cancer therapeutics 2010;9(11):3074-82.
2010: Jay W Tichelaar; Ying Yan; Qing Tan; Yian Wang; Richard D Estensen; Matthew R Young; Nancy H Colburn; Hulian Yin; Colleen Goodin; Marshall W Anderson; Ming You
A dominant-negative c-jun mutant inhibits lung carcinogenesis in mice.
Cancer prevention research (Philadelphia, Pa.) 2010;3(9):1148-56.
2010: Haris G Vikis; Erin N Jackson; Alexander S Krupnick; Andrew Franklin; Andrew E Gelman; Qiong Chen; David Piwnica-Worms; Ming You
Strain-specific susceptibility for pulmonary metastasis of sarcoma 180 cells in inbred mice.
Cancer research 2010;70(12):4859-67.
2010: Qi Zhang; Huijing Fu; Jing Pan; Jun He; Seto Ryota; Yukihiko Hara; Yian Wang; Ronald A Lubet; Ming You
Effect of dietary Polyphenon E and EGCG on lung tumorigenesis in A/J Mice.
Pharmaceutical research 2010;27(6):1066-71.
2010: Pengyuan Liu; Ping Yang; Xifeng Wu; Haris G Vikis; Yan Lu; Yian Wang; Ann Grossbart Schwartz; Susan Pinney; Mariza de Andrade; Adi Gazdar; Colette Gaba; Diptasri Mandal; Juwon Lee; Elena Kupert; Daniela Seminara; John Minna; Joan E Bailey-Wilson; Margaret Spitz; Christopher I Amos; Marshall W Anderson; Ming You
A second genetic variant on chromosome 15q24-25.1 associates with lung cancer.
Cancer research 2010;70(8):3128-35.
2010: Christopher I Amos; Susan M Pinney; Yafang Li; Elena Kupert; Juwon Lee; Mariza A de Andrade; Ping Yang; Ann Grossbart Schwartz; Pam R Fain; Adi Gazdar; John Minna; Jonathan S Wiest; Dong Zeng; Henry Rothschild; Diptasri Mandal; Ming You; Teresa Coons; Colette Gaba; Joan E Bailey-Wilson; Marshall W Anderson
A susceptibility locus on chromosome 6q greatly increases lung cancer risk among light and never smokers.
Cancer research 2010;70(6):2359-67.
2010: Yan Lu; P Liu; M James; Haris G Vikis; H Liu; W Wen; A Franklin; Ming You
Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor.
Oncogene 2010;29(7):1041-9.
2010: Pengyuan Liu; Haris G Vikis; Yan Lu; Yian Wang; Ann Grossbart Schwartz; Susan Pinney; Ping Yang; Mariza de Andrade; Adi Gazdar; Colette Gaba; Diptasri Mandal; Juwon Lee; Elena Kupert; Daniela Seminara; John Minna; Joan E Bailey-Wilson; Christopher I Amos; Marshall W Anderson; Ming You
Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010;19(2):517-24.
2010: Jing Pan; Qi Zhang; Yian Wang; Ming You
26S proteasome activity is down-regulated in lung cancer stem-like cells propagated in vitro.
PloS one 2010;5(10):e13298.
2009: Yian Wang; Weidong Wen; Yijun Yi; Zhongqiu Zhang; Ronald A Lubet; Ming You
Preventive effects of bexarotene and budesonide in a genetically engineered mouse model of small cell lung cancer.
Cancer prevention research (Philadelphia, Pa.) 2009;2(12):1059-64.
2009: Ronald A Lubet; Ruisheng Yao; Clinton J Grubbs; Ming You; Yian Wang
Induced expression of drug metabolizing enzymes by preventive agents: role of the antioxidant response element.
Chemico-biological interactions 2009;182(1):22-8.
2009: Yan Liu; Pengyuan Liu; Weidong Wen; Michael A James; Yian Wang; Joan E Bailey-Wilson; Christopher I Amos; Susan Pinney; Ping Yang; Mariza de Andrade; Gloria M Petersen; Jonathan S Wiest; Pamela R Fain; Ann Grossbart Schwartz; Adi Gazdar; Colette Gaba; Henry Rothschild; Diptasri Mandal; Elena Kupert; Juwon Lee; Daniela Seminara; John Minna; Marshall W Anderson; Ming You
Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1.
Cancer research 2009;69(19):7844-50.
2009: Jen C Wang; Carlos Cruchaga; Nancy L Saccone; Sarah Bertelsen; Pengyuan Liu; John Budde; Weimin Duan; Louis Fox; Richard A Grucza; Jason Kern; Kevin Mayo; Oliver Reyes; John Rice; Scott F Saccone; Noah Spiegel; Joseph H Steinbach; Jerry A Stitzel; Marshall W Anderson; Ming You; Victoria L Stevens; Laura J Bierut; Alison Goate
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
Human molecular genetics 2009;18(16):3125-35.
2009: Peng-Yuan Liu; Haris G Vikis; Michael James; Yan Lu; Dao-Long Wang; Hong-Bo Liu; Wei-Dong Wen; Yian Wang; Ming You
Identification of Las2, a major modifier gene affecting the Pas1 mouse lung tumor susceptibility locus.
Cancer research 2009;69(15):6290-8.
2009: Yian Wang; Zhongqiu Zhang; Joel R Garbow; Douglas Rowland; Ronald A Lubet; Daniel Sit; Francis Law; Ming You
Chemoprevention of lung squamous cell carcinoma in mice by a mixture of Chinese herbs.
Cancer prevention research (Philadelphia, Pa.) 2009;2(7):634-40.
2009: Huijing Fu; Jun He; Fan Mei; Qi Zhang; Yukihiko Hara; Seto Ryota; Ronald A Lubet; Ruth Chen; Da-Ren Chen; Ming You
Lung cancer inhibitory effect of epigallocatechin-3-gallate is dependent on its presence in a complex mixture (polyphenon E).
Cancer prevention research (Philadelphia, Pa.) 2009;2(6):531-7.
2009: Michael A James; Yan Lu; Yan Liu; Haris G Vikis; Ming You
RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway.
Cancer research 2009;69(5):2108-16.
2008: Pengyuan Liu; Haris G Vikis; Daolong Wang; Yan Lu; Yian Wang; Ann Grossbart Schwartz; Susan Pinney; Ping Yang; Mariza de Andrade; Gloria M Petersen; Jonathan S Wiest; Pamela R Fain; Adi Gazdar; Colette Gaba; Henry Rothschild; Diptasri Mandal; Teresa Coons; Juwon Lee; Elena Kupert; Daniela Seminara; John Minna; Joan E Bailey-Wilson; Xifeng Wu; Margaret R Spitz; Timothy Eisen; Richard S Houlston; Christopher I Amos; Marshall W Anderson; Ming You
Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer.
Journal of the National Cancer Institute 2008;100(18):1326-30.
2008: Yian Wang; Zhongqiu Zhang; Yan Lu; Ruisheng Yao; Dongmei Jia; Weidong Wen; MC LaRegina; Keith Crist; Ronald Lubet; Ming You
Enhanced susceptibility to chemical induction of ovarian tumors in mice with a germ line p53 mutation.
Molecular cancer research : MCR 2008;6(1):99-109.
2007: Yan Liu; Haris G Vikis; Yijun Yi; Manabu Futamura; Yian Wang; Ming You
Degradation of lung adenoma susceptibility 1, a major candidate mouse lung tumor modifier, is required for cell cycle progression.
Cancer research 2007;67(21):10207-13.
2007: Haris G Vikis; Mitsuo Sato; Michael James; Daolong Wang; Yian Wang; Min Wang; Dongmei Jia; Yan Liu; Joan E Bailey-Wilson; Christopher I Amos; Susan Pinney; Gloria M Petersen; Mariza de Andrade; Ping Yang; Jonathan S Wiest; Pamela R Fain; Ann Grossbart Schwartz; Adi F Gazdar; Colette Gaba; Henry Rothschild; Diptasri Mandal; Elena Kupert; Daniela Seminara; Avinash Viswanathan; Ramaswamy Govindan; John D Minna; Marshall W Anderson; Ming You
EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity.
Cancer research 2007;67(10):4665-70.
2007: Ying Yan; Julie Cook; Jay McQuillan; Guifang Zhang; Cory J Hitzman; Yian Wang; Timothy Scott Wiedmann; Ming You
Chemopreventive effect of aerosolized polyphenon E on lung tumorigenesis in A/J mice.
Neoplasia (New York, N.Y.) 2007;9(5):401-5.
2007: Min Wang; Zhongqiu Zhang; Zhuo Zhang; Haris G Vikis; Ying Yan; Yian Wang; Ming You
Fine mapping and candidate gene analyses of pulmonary adenoma resistance 1, a major genetic determinant of mouse lung adenoma resistance.
Cancer research 2007;67(6):2508-16.
2007: Ruisheng Yao; Yijun Yi; Clinton J Grubbs; Ronald A Lubet; Ming You
Gene expression profiling of chemically induced rat bladder tumors.
Neoplasia (New York, N.Y.) 2007;9(3):207-21.
2007: Yan Lu; Yijun Yi; Pengyuan Liu; Weidong Wen; Michael James; Daolong Wang; Ming You
Common human cancer genes discovered by integrated gene-expression analysis.
PloS one 2007;2(11):e1149.
2007: Pengyuan Liu; Haris G Vikis; Yan Lu; Daolong Wang; Ming You
Large-scale in silico mapping of complex quantitative traits in inbred mice.
PloS one 2007;2(7):e651.
2007: Min Wang; Haris G Vikis; Yian Wang; Dongmei Jia; Daolong Wang; Laura J Bierut; Joan E Bailey-Wilson; Christopher I Amos; Susan Pinney; Gloria M Petersen; Mariza de Andrade; Ping Yang; Jonathan S Wiest; Pamela R Fain; Ann Grossbart Schwartz; Adi F Gazdar; John D Minna; Colette Gaba; Henry Rothschild; Diptasri Mandal; Elena Kupert; Daniela Seminara; Yan Liu; Avinash Viswanathan; Ramaswamy Govindan; Marshall W Anderson; Ming You
Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1.
Cancer research 2007;67(1):93-9.
2006: Yan Lu; William Lemon; Peng-Yuan Liu; Yijun Yi; Carl Morrison; Ping Yang; Zhifu Sun; Janos Szoke; William L Gerald; Mark Watson; Ramaswamy Govindan; Ming You
A gene expression signature predicts survival of patients with stage I non-small cell lung cancer.
PLoS medicine 2006;3(12):e467.
2006: Ying Yan; Yan Lu; Min Wang; Haris G Vikis; Ruisheng Yao; Yian Wang; Ronald A Lubet; Ming You
Effect of an epidermal growth factor receptor inhibitor in mouse models of lung cancer.
Molecular cancer research : MCR 2006;4(12):971-81.
2006: Pengyuan Liu; Yian Wang; Haris G Vikis; Anna Maciag; Daolong Wang; Yan Lu; Yan Liu; Ming You
Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice.
Nature genetics 2006;38(8):888-95.
2006: Ruisheng Yao; Yian Wang; Yan Lu; William J Lemon; David W End; Clinton J Grubbs; Ronald A Lubet; Ming You
Efficacy of the farnesyltransferase inhibitor R115777 in a rat mammary tumor model: role of Ha-ras mutations and use of microarray analysis in identifying potential targets.
Carcinogenesis 2006;27(7):1420-31.
2006: Zhongqiu Zhang; Yian Wang; Ruisheng Yao; Jie Li; Ronald A Lubet; Ming You
p53 Transgenic mice are highly susceptible to 4-nitroquinoline-1-oxide-induced oral cancer.
Molecular cancer research : MCR 2006;4(6):401-10.
2006: Ronald A Lubet; Konstantin Christov-Tzelkov; Ming You; Ruisheng Yao; Vernon E Steele; David W End; M Margaret Juliana; Clinton J Grubbs
Effects of the farnesyl transferase inhibitor R115777 (Zarnestra) on mammary carcinogenesis: prevention, therapy, and role of HaRas mutations.
Molecular cancer therapeutics 2006;5(4):1073-8.
2006: Yian Wang; Ruisheng Yao; Anna Maciag; Clinton J Grubbs; Ronald A Lubet; Ming You
Organ-specific expression profiles of rat mammary gland, liver, and lung tissues treated with targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide.
Molecular cancer therapeutics 2006;5(4):1060-72.
2006: Yian Wang; Z Zhang; Ronald A Lubet; Ming You
A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice.
Oncogene 2006;25(8):1277-80.
2006: Yan Lu; Ruisheng Yao; Ying Yan; Yian Wang; Yukihiko Hara; Ronald A Lubet; Ming You
A gene expression signature that can predict green tea exposure and chemopreventive efficacy of lung cancer in mice.
Cancer research 2006;66(4):1956-63.
2006: Julie Clark; Ming You
Chemoprevention of lung cancer by tea.
Molecular nutrition & food research 2006;50(2):144-51.
2006: Ying Yan; Yian Wang; Qing Tan; Yukihiko Hara; Taik-Koo Yun; Ronald A Lubet; Ming You
Efficacy of polyphenon E, red ginseng, and rapamycin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice.
Neoplasia (New York, N.Y.) 2006;8(1):52-8.
2005: Ying Yan; Yian Wang; Qing Tan; Ronald A Lubet; Ming You
Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice.
Neoplasia (New York, N.Y.) 2005;7(12):1053-7.
2005: Zhongqiu Zhang; Ruisheng Yao; Jie Li; Yian Wang; Charles W Boone; Ronald A Lubet; Ming You
Induction of invasive mouse skin carcinomas in transgenic mice with mutations in both H-ras and p53.
Molecular cancer research : MCR 2005;3(10):563-74.
2005: Keith Crist; Zhongqiu Zhang; Ming You; William Gunning; Phillip B Conran; Vernon E Steele; Ronald A Lubet
Characterization of rat ovarian adenocarcinomas developed in response to direct instillation of 7,12-dimethylbenz[a]anthracene (DMBA) coated suture.
Carcinogenesis 2005;26(5):951-7.
2005: Min Wang; Manabu Futamura; Yian Wang; Ming You
Pas1c1 is a candidate for the mouse pulmonary adenoma susceptibility 1 locus.
Oncogene 2005;24(11):1958-63.
2005: Min Wang; Yian Wang; Ming You; Theodora R Devereux
Analysis of the Par2 modifier of pulmonary adenoma formation in mice.
Experimental lung research 2005;31(2):193-204.
2005: Ruisheng Yao; Yian Wang; Francesco D'Agostini; Alberto Izzotti; Ronald A Lubet; Ming You; Silvio De Flora
K-ras mutations in lung tumors from p53 mutant mice exposed to cigarette smoke.
Experimental lung research 2005;31(2):271-81.
2005: Bin Chen; Yian Wang; Ming You
Characterization of two protein-binding sites in the second intron of the mouse K-ras gene.
Experimental lung research 2005;31(2):179-92.
2005: Min Wang; Yian Wang; Ming You
Identification of genetic polymorphisms through comparative DNA sequence analysis on the K-ras gene: implications for lung tumor susceptibility.
Experimental lung research 2005;31(2):165-77.
2004: Ruisheng Yao; Yian Wang; William J Lemon; Ronald A Lubet; Ming You
Budesonide exerts its chemopreventive efficacy during mouse lung tumorigenesis by modulating gene expressions.
Oncogene 2004;23(46):7746-52.
2004: Ruisheng Yao; William J Lemon; Yian Wang; Clinton J Grubbs; Ronald A Lubet; Ming You
Altered gene expression profile in mouse bladder cancers induced by hydroxybutyl(butyl)nitrosamine.
Neoplasia (New York, N.Y.) 2004;6(5):569-77.
2004: Allison E Bonner; Yian Wang; Ming You
Gene expression profiling of mouse teratocarcinomas uncovers epigenetic changes associated with the transformation of mouse embryonic stem cells.
Neoplasia (New York, N.Y.) 2004;6(5):490-502.
2004: Joan E Bailey-Wilson; Christopher I Amos; Susan Pinney; Gloria M Petersen; Mariza de Andrade; Jonathan S Wiest; Pamela R Fain; Ann Grossbart Schwartz; Ming You; Wilbur Franklin; C Klein; Adi F Gazdar; Henry Rothschild; Diptasri Mandal; Teresa A Coons; Joshua P Slusser; J Lee; Colette Gaba; Elena Kupert; A Perez; X Zhou; D Zeng; Q Liu; Qing Zhang; Daniela Seminara; John D Minna; Marshall W Anderson
A major lung cancer susceptibility locus maps to chromosome 6q23-25.
American journal of human genetics 2004;75(3):460-74.
2004: Zhongqiu Zhang; Yian Wang; Ruisheng Yao; Jie Li; Ying Yan; Marie La Regina; William L Lemon; Clinton J Grubbs; Ronald A Lubet; Ming You
Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models.
Oncogene 2004;23(21):3841-50.
2004: Ronald A Lubet; Zhongqiu Zhang; Yian Wang; Ming You
Chemoprevention of lung cancer in transgenic mice.
Chest 2004;125(5 Suppl):144S-7S.
2004: Christopher R Herzog; Nomar Bodon; Brian Pittman; Robert R Maronpot; Thomas E Massey; Marshall W Anderson; Ming You; Theodora R Devereux
Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression.
Oncogene 2004;23(17):3033-9.
2004: Min Wang; Theodora R Devereux; Haris G Vikis; Scott D McCulloch; Wanda Holliday; Colleen H Anna; Yian Wang; Katarzyna Bebenek; Thomas A Kunkel; Kunliang Guan; Ming You
Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia.
Cancer research 2004;64(6):1924-31.
2004: Allison E Bonner; William J Lemon; Theodora R Devereux; Ronald A Lubet; Ming You
Molecular profiling of mouse lung tumors: association with tumor progression, lung development, and human lung adenocarcinomas.
Oncogene 2004;23(5):1166-76.
2003: Qunmin Zhou; Kottil W. Rammohan; Shili Lin; Nikki Robinson; Ou Li; Xingluo Liu; Xue-Feng Bai; Lijie Yin; Bruce Scarberry; Peishuang Du; Ming You; Kunliang Guan; Pan Zheng; Yang Liu
CD24 is a genetic modifier for risk and progression of multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):15041-6.
2003: Heike Bernert; Kenji Sekikawa; Richard Radcliffe; Fuad A Iraqi; Ming You; Alvin M Malkinson
Tnfa and Il-10 deficiencies have contrasting effects on lung tumor susceptibility: gender-dependent modulation of IL-10 haploinsufficiency.
Molecular carcinogenesis 2003;38(3):117-23.
2003: Zhongqiu Zhang; Manabu Futamura; Haris G Vikis; Min Wang; Jie Li; Yian Wang; Kun-Liang Guan; Ming You
Positional cloning of the major quantitative trait locus underlying lung tumor susceptibility in mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12642-7.
2003: Zhongqiu Zhang; Yian Wang; Laura E Lantry; Elizabeth Kastens; Gongjie Liu; Andrew D Hamilton; Said M Sebti; Ronald A Lubet; Ming You
Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf.
Oncogene 2003;22(40):6257-65.
2003: Yian Wang; Zhongqiu Zhang; Elizabeth Kastens; Ronald A Lubet; Ming You
Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: differential chemopreventive effect of budesonide in wild-type and mutant A/J mice.
Cancer research 2003;63(15):4389-95.
2003: Jie Li; Zhongqiu Zhang; Zunyan Dai; Anthony P Popkie; Christoph Plass; Carl Morrison; Yian Wang; Ming You
RASSF1A promoter methylation and Kras2 mutations in non small cell lung cancer.
Neoplasia (New York, N.Y.) 2003;5(4):362-6.
2003: Min Wang; William J Lemon; Gongjie Liu; Yian Wang; Fuad A Iraqi; Alvin M Malkinson; Ming You
Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines.
Cancer research 2003;63(12):3317-24.
2003: Allison E Bonner; William J Lemon; Ming You
Gene expression signatures identify novel regulatory pathways during murine lung development: implications for lung tumorigenesis.
Journal of medical genetics 2003;40(6):408-17.
2003: Jie Li; Zhongqiu Zhang; Zunyan Dai; Christoph Plass; Carl Morrison; Yian Wang; Jonathan S Wiest; Marshall W Anderson; Ming You
LOH of chromosome 12p correlates with Kras2 mutation in non-small cell lung cancer.
Oncogene 2003;22(8):1243-6.
2003: Ruisheng Yao; Yian Wang; Ronald A Lubet; Ming You
Differential gene expression in chemically induced mouse lung adenomas.
Neoplasia (New York, N.Y.) 2003;5(1):41-52.
2002: Daolong Wang; William J Lemon; Ming You
Linkage disequilibrium mapping of novel lung tumor susceptibility quantitative trait loci in mice.
Oncogene 2002;21(44):6858-65.
2002: William J Lemon; H Bernert; H Sun; Yian Wang; Ming You
Identification of candidate lung cancer susceptibility genes in mouse using oligonucleotide arrays.
Journal of medical genetics 2002;39(9):644-55.
2002: Zhongqiu Zhang; Yian Wang; Christopher R Herzog; Gongjie Liu; Han-Woong Lee; Ronald A DePinho; Ming You
A strong candidate gene for the Papg1 locus on mouse chromosome 4 affecting lung tumor progression.
Oncogene 2002;21(38):5960-6.
2002: Ruisheng Yao; Yian Wang; Ronald A Lubet; Ming You
Differentially expressed genes associated with mouse lung tumor progression.
Oncogene 2002;21(37):5814-21.
2002: Zhongqiu Zhang; Jie Li; Laura E Lantry; Yian Wang; Roger W Wiseman; Ronald A Lubet; Ming You
p53 transgenic mice are highly susceptible to 1, 2-dimethylhydrazine-induced uterine sarcomas.
Cancer research 2002;62(11):3024-9.
2002: Susan Pohlod-Miller; James Fanning; Ping Gu; Keith Crist; Ming You
Detection of genomic alterations in human endometrial cancer by two-dimensional gel electrophoresis.
American journal of obstetrics and gynecology 2002;186(5):855-7.
2002: Amy L McDoniels-Silvers; Caramella F Nimri; Gary D Stoner; Ronald A Lubet; Ming You
Differential gene expression in human lung adenocarcinomas and squamous cell carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(4):1127-38.
2002: Amy L McDoniels-Silvers; Gary D Stoner; Ronald A Lubet; Ming You
Differential expression of critical cellular genes in human lung adenocarcinomas and squamous cell carcinomas in comparison to normal lung tissues.
Neoplasia (New York, N.Y.) 2002;4(2):141-50.
2001: Yian Wang; L Hu; Ruisheng Yao; M Wang; Keith Crist; Clinton J Grubbs; Gary L Johanning; Ronald A Lubet; Ming You
Altered gene expression profile in chemically induced rat mammary adenocarcinomas and its modulation by an aromatase inhibitor.
Oncogene 2001;20(53):7710-21.
2001: Zhongqiu Zhang; Yian Wang; Haris G Vikis; L Johnson; G Liu; Jie Li; Marshall W Anderson; R C Sills; HL Hong; Theodora R Devereux; T Jacks; Kun-Liang Guan; Ming You
Wildtype Kras2 can inhibit lung carcinogenesis in mice.
Nature genetics 2001;29(1):25-33.
2001: Amy L McDoniels-Silvers; CR Herzog; F L Tyson; Alvin M Malkinson; Ming You
Inactivation of both Rb and p53 pathways in mouse lung epithelial cell lines.
Experimental lung research 2001;27(3):297-318.
2001: Yian Wang; Ming You; Y Wang
Alternative splicing of the K-ras gene in mouse tissues and cell lines.
Experimental lung research 2001;27(3):255-67.
2001: L Lin; Yian Wang; G Bergman; Gary J Kelloff; Ronald A Lubet; Ming You
Detection of differentially expressed genes in mouse lung adenocarcinomas.
Experimental lung research 2001;27(3):217-29.
2001: Christopher R Herzog; Keith Crist; Carol L K Sabourin; Gary J Kelloff; C W Boone; Gary D Stoner; Ming You
Chromosome 3p tumor-suppressor gene alterations in cervical carcinomas.
Molecular carcinogenesis 2001;30(3):159-68.
2000: Laura E Lantry; Zhongqiu Zhang; Keith Crist; Yian Wang; M Hara; A Zeeck; Ronald A Lubet; Ming You
Chemopreventive efficacy of promising farnesyltransferase inhibitors.
Experimental lung research 2000;26(8):773-90.
2000: R Yao; Nathalie Rioux; André Castonguay; Ming You
Inhibition of COX-2 and induction of apoptosis: two determinants of nonsteroidal anti-inflammatory drugs' chemopreventive efficacies in mouse lung tumorigenesis.
Experimental lung research 2000;26(8):731-42.
2000: J Liu; P Gu; G Bergman; Gary J Kelloff; C W Boone; Ming You; Yian Wang
Detection of genetic alterations in mouse lung adenocarcinomas by two-dimensional gel electrophoresis.
Experimental lung research 2000;26(8):651-8.
2000: Zhongqiu Zhang; Lin Lin; G Liu; M Wang; J Hill; Yian Wang; Ming You; Theodora R Devereux
Fine mapping and characterization of candidate lung tumor resistance genes for the Par2 locus on mouse chromosome 18.
Experimental lung research 2000;26(8):627-39.
2000: Ronald A Lubet; Z Zhang; R W Wiseman; Ming You
Use of p53 transgenic mice in the development of cancer models for multiple purposes.
Experimental lung research 2000;26(8):581-93.
2000: Zhongqiu Zhang; Q Liu; Laura E Lantry; Yian Wang; Gary J Kelloff; M W Anderson; R W Wiseman; Ronald A Lubet; Ming You
A germ-line p53 mutation accelerates pulmonary tumorigenesis: p53-independent efficacy of chemopreventive agents green tea or dexamethasone/myo-inositol and chemotherapeutic agents taxol or adriamycin.
Cancer research 2000;60(4):901-7.
2000: Laura E Lantry; Zhongqiu Zhang; R Yao; Keith Crist; Yian Wang; J Ohkanda; A D Hamilton; Said M Sebti; Ronald A Lubet; Ming You
Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Carcinogenesis 2000;21(1):113-6.
1999: CR Herzog; S Noh; Laura E Lantry; K L Guan; Ming You
Cdkn2a encodes functional variation of p16INK4a but not p19ARF, which confers selection in mouse lung tumorigenesis.
Molecular carcinogenesis 1999;25(2):92-8.
1999: Laura E Lantry; Zhongqiu Zhang; Keith Crist; Yian Wang; Gary J Kelloff; Ronald A Lubet; Ming You
5-Aza-2'-deoxycytidine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone-induced primary mouse lung tumor model.
Carcinogenesis 1999;20(2):343-6.
1998: Michael F W Festing; Lin Lin; Theodora R Devereux; F Gao; A Yang; Colleen H Anna; C M White; Alvin M Malkinson; Ming You
At least four loci and gender are associated with susceptibility to the chemical induction of lung adenomas in A/J x BALB/c mice.
Genomics 1998;53(2):129-36.
1998: Ming You; G Bergman
Preclinical and clinical models of lung cancer chemoprevention.
Hematology/oncology clinics of North America 1998;12(5):1037-53.
1998: Ronald A Lubet; Vernon E Steele; R DeCoster; C Bowden; Ming You; M Margaret Juliana; Isao Eto; Gary J Kelloff; Clinton J Grubbs
Chemopreventive effects of the aromatase inhibitor vorozole (R 83842) in the methylnitrosourea-induced mammary cancer model.
Carcinogenesis 1998;19(8):1345-51.
1998: Q Liu; Yian Wang; Keith Crist; Z Y Wang; You-Rong Lou; M T Huang; A H Conney; Ming You
Effect of green tea on p53 mutation distribution in ultraviolet B radiation-induced mouse skin tumors.
Carcinogenesis 1998;19(7):1257-62.
1998: Carol L K Sabourin; Q S Wang; S L Ralston; J Evans; J Coate; Christopher R Herzog; S L Jones; Christopher M Weghorst; Gary J Kelloff; Ronald A Lubet; Ming You; Gary D Stoner
Expression of cell cycle proteins in 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung tumors.
Experimental lung research 1998;24(4):499-521.
1998: L Lin; Michael F W Festing; Theodora R Devereux; Keith Crist; S C Christiansen; Yian Wang; A Yang; Karen L Svenson; B Paigen; Alvin M Malkinson; Ming You
Additional evidence that the K-ras protooncogene is a candidate for the major mouse pulmonary adenoma susceptibility (Pas-1) gene.
Experimental lung research 1998;24(4):481-97.
1998: Ronald A Lubet; Gary B Gordon; Russell A Prough; X D Lei; Ming You; Yunfei Wang; Clinton J Grubbs; Vernon E Steele; Gary J Kelloff; C F Thomas; R D Moon
Modulation of methylnitrosourea-induced breast cancer in Sprague Dawley rats by dehydroepiandrosterone: dose-dependent inhibition, effects of limited exposure, effects on peroxisomal enzymes, and lack of effects on levels of Ha-Ras mutations.
Cancer research 1998;58(5):921-6.
1998: V I Oreffo; S Robinson; Ming You; M C Wu; Alvin M Malkinson
Decreased expression of the adenomatous polyposis coli (Apc) and mutated in colorectal cancer (Mcc) genes in mouse lung neoplasia.
Molecular carcinogenesis 1998;21(1):37-49.
1997: Theodora R Devereux; Colleen H Anna; Arti C Patel; C M White; Michael F W Festing; Ming You
Smad4 (homolog of human DPC4) and Smad2 (homolog of human JV18-1): candidates for murine lung tumor resistance and suppressor genes.
Carcinogenesis 1997;18(9):1751-5.
1997: S A Matzinger; B Chen; Yian Wang; Keith Crist; G D Stoner; Gary J Kelloff; Ronald A Lubet; Ming You
Tissue-specific expression of the K-ras allele from the A/J parent in (A/J x TSG-p53) F1 mice.
Gene 1997;188(2):261-9.
1997: Jürgen K Naggert; Karen L Svenson; Lin Lin; Y Cheah; Patsy M Nishina; J Mu; T R Devereux; Ming You; Beverly Paigen
An additional 136 SSLP markers typed for the AXB and BXA recombinant inbred mouse strains.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(3):209-11.
1997: Keith Crist; Yian Wang; Ronald A Lubet; Vernon E Steele; Gary J Kelloff; Ming You
Effect of early vs. late administration of 4-hydroxyphenylretinamide (4-HPR) on N-methyl-N-nitrosourea (MNU)-induced mammary tumorigenesis.
Journal of cellular biochemistry. Supplement 1997;27():92-9.
1997: Laura E Lantry; Zhongqiu Zhang; F Gao; Keith Crist; Yian Wang; Gary J Kelloff; Ronald A Lubet; Ming You
Chemopreventive effect of perillyl alcohol on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced tumorigenesis in (C3H/HeJ X A/J)F1 mouse lung.
Journal of cellular biochemistry. Supplement 1997;27():20-5.
1997: L Hu; L Lin; Keith Crist; Gary J Kelloff; Vernon E Steele; Ronald A Lubet; Ming You; Yian Wang
Detection of differentially expressed genes in methylnitrosourea-induced rat mammary adenocarcinomas.
Journal of cellular biochemistry. Supplement 1997;28-29():117-24.
1997: CR Herzog; Ronald A Lubet; Ming You
Genetic alterations in mouse lung tumors: implications for cancer chemoprevention.
Journal of cellular biochemistry. Supplement 1997;28-29():49-63.
1997: CR Herzog; Ming You
Sequence variation and chromosomal mapping of the murine Cdkn2a tumor suppressor gene.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(1):65-6.
1996: E V Soloff; CR Herzog; Ming You
The 5'-flanking region of the E1 alpha form of the murine p16INK4a (MTS1) gene.
Gene 1996;180(1-2):213-5.
1996: CR Herzog; E V Soloff; A L McDoniels; F L Tyson; A M Malkinson; A Haugen-Strano; Roger W Wiseman; M W Anderson; Ming You
Homozygous codeletion and differential decreased expression of p15INK4b, p16INK4a-alpha and p16INK4a-beta in mouse lung tumor cells.
Oncogene 1996;13(9):1885-91.
1996: CR Herzog; B Chen; Y Wang; Herman A J Schut; Ming You
Loss of heterozygosity on chromosomes 1, 11, 12, and 14 in hybrid mouse lung adenocarcinomas.
Molecular carcinogenesis 1996;16(2):83-90.
1996: Keith Crist; R D Fuller; B Chaudhuri; P Chaudhuri; Ming You
Brief communication, P53 accumulation in N-methyl-N-nitrosourea-induced rat mammary tumors.
Toxicologic pathology 1996;24(3):370-5.
1996: Keith Crist; K Kim; P J Goldblatt; C W Boone; Gary J Kelloff; Ming You
DNA quantification in cervical intraepithelial neoplasia thick tissue sections by confocal laser scanning microscopy.
Journal of cellular biochemistry. Supplement 1996;25():49-56.
1996: J Liu; Yian Wang; P Gu; J Patrick; Keith Crist; Carol L K Sabourin; Gary D Stoner; M F Mitchell; J D Fanning; K Kim; P J Goldblatt; Gary J Kelloff; C W Boone; Ming You
Detection of genomic alterations in human cervical cancer by two-dimensional gel electrophoresis.
Journal of cellular biochemistry. Supplement 1996;25():41-8.
1995: CR Herzog; Y Wang; Ming You
Allelic loss of distal chromosome 4 in mouse lung tumors localize a putative tumor suppressor gene to a region homologous with human chromosome 1p36.
Oncogene 1995;11(9):1811-5.
1995: S A Matzinger; Keith Crist; Gary D Stoner; M W Anderson; Michael A Pereira; V E Steele; Gary J Kelloff; Ronald A Lubet; Ming You
K-ras mutations in lung tumors from A/J and A/J x TSG-p53 F1 mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and phenethyl isothiocyanate.
Carcinogenesis 1995;16(10):2487-92.
1995: Rajendra Mehta; Jianhua Liu; Andreas I Constantinou; C F Thomas; M Hawthorne; Ming You; C Gerhüser; John M Pezzuto; Richard C Moon; Robert M Moriarty
Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage.
Carcinogenesis 1995;16(2):399-404.
1994: B Chen; L You; Yian Wang; Gary D Stoner; Ming You
Allele-specific activation and expression of the K-ras gene in hybrid mouse lung tumors induced by chemical carcinogens.
Carcinogenesis 1994;15(9):2031-5.
1994: S A Matzinger; William Gunning; Ming You; A Castonguay
Ki-ras mutations in 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-initiated and butylated hydroxytoluene-promoted lung tumors in A/J mice.
Molecular carcinogenesis 1994;11(1):42-8.
1994: CR Herzog; Roger W Wiseman; Ming You
Deletion mapping of a putative tumor suppressor gene on chromosome 4 in mouse lung tumors.
Cancer research 1994;54(15):4007-10.
1994: B Chen; L Johanson; J S Wiest; M W Anderson; Ming You
The second intron of the K-ras gene contains regulatory elements associated with mouse lung tumor susceptibility.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1589-93.
1993: B Chen; L Liu; A Castonguay; Robert R Maronpot; M W Anderson; Ming You
Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors.
Carcinogenesis 1993;14(8):1603-8.
1993: Ming You; Yian Wang; B Nash; Gary D Stoner
K-ras mutations in benzotrichloride-induced lung tumors of A/J mice.
Carcinogenesis 1993;14(6):1247-9.
1993: Yian Wang; Y Wang; G Stoner; Ming You
ras mutations in 2-acetylaminofluorene-induced lung and liver tumors from C3H/HeJ and (C3H x A/J)F1 mice.
Cancer research 1993;53(7):1620-4.
1993: CR Herzog; Herman A J Schut; Robert R Maronpot; Ming You
ras mutations in 2-amino-3-methylimidazo-[4,5-f]quinoline-induced tumors in the CDF1 mouse.
Molecular carcinogenesis 1993;8(3):202-7.
1992: M W Anderson; S H Reynolds; Ming You; R M Maronpot
Role of proto-oncogene activation in carcinogenesis.
Environmental health perspectives 1992;98():13-24.
1992: Ming You; Yian Wang; A M Lineen; William Gunning; Gary D Stoner; M W Anderson
Mutagenesis of the K-ras protooncogene in mouse lung tumors induced by N-ethyl-N-nitrosourea or N-nitrosodiethylamine.
Carcinogenesis 1992;13(9):1583-6.
1992: Ming You; Yian Wang; G Stoner; L You; Robert R Maronpot; S H Reynolds; M Anderson
Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(13):5804-8.
1992: S H Reynolds; J S Wiest; Theodora R Devereux; M W Anderson; Ming You
Protooncogene activation in spontaneously occurring and chemically induced rodent and human lung tumors.
Progress in clinical and biological research 1992;376():303-20.
1991: Ming You; Yian Wang; A Lineen; Gary D Stoner; L A You; Robert R Maronpot; M W Anderson
Activation of protooncogenes in mouse lung tumors.
Experimental lung research 1991;17(2):389-400.
1991: U Candrian; Ming You; T Goodrow; Robert R Maronpot; S H Reynolds; M W Anderson
Activation of protooncogenes in spontaneously occurring non-liver tumors from C57BL/6 x C3H F1 mice.
Cancer research 1991;51(4):1148-53.
1991: M W Anderson; Ming You; S H Reynolds
Proto-oncogene activation in rodent and human tumors.
Advances in experimental medicine and biology 1991;283():235-43.
1991: Gary D Stoner; M E Kaighn; Roger R Reddel; James Resau; D Bowman; Zenya Naito; Norio Matsukura; Ming You; A J Galati; Curtis C Harris
Establishment and characterization of SV40 T-antigen immortalized human esophageal epithelial cells.
Cancer research 1991;51(1):365-71.
1990: Yian Wang; Ming You; S H Reynolds; Gary D Stoner; M W Anderson
Mutational activation of the cellular Harvey ras oncogene in rat esophageal papillomas induced by methylbenzylnitrosamine.
Cancer research 1990;50(5):1591-5.
1989: Ming You; U Candrian; Robert R Maronpot; G D Stoner; M W Anderson
Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3070-4.