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Bryan Young
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39
Chaplin, Tracy
34
Lillington, Debra
25
Lister, Andrew
14
Debernardi, Silvana
12
Saha, Vaskar
10
Foot, Nicola
10
Rohatiner, Ama
8
Mao, Xin
8
Lu, Yong-Jie
8
Meerabux, Joanne
8
Amess, John
8
Russell-Jones, Robin
8
Strefford, Jon
7
Skoulakis, Spyros
7
Oliver, R T D
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All Publications
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2009: Forshew Tim; Tatevossian Ruth G; Lawson Andrew R J; Ma Jing; Neale Geoff; Ogunkolade Babatunji W; Jones Tania A; Aarum Johan; Dalton James; Bailey Simon; Chaplin Tracy; Carter Rowena L; Gajjar Amar; Broniscer Alberto; Young Bryan D; Ellison David W; Sheer Denise
Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.
The Journal of pathology 2009;218(2):172-81.
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2009: Purdie Karin J; Harwood Catherine A; Gulati Abha; Chaplin Tracy; Lambert Sally R; Cerio Rino; Kelly Gavin P; Cazier Jean-Baptiste; Young Bryan D; Leigh Irene M; Proby Charlotte M
Single nucleotide polymorphism array analysis defines a specific genetic fingerprint for well-differentiated cutaneous SCCs.
The Journal of investigative dermatology 2009;129(6):1562-8.
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2009: O'Shea Derville; O'Riain Ciarán; Gupta Manu; Waters Rachel; Yang Youwen; Wrench David; Gribben John; Rosenwald Andreas; Ott German; Rimsza Lisa M; Holte Harald; Cazier Jean-Baptiste; Johnson Nathalie A; Campo Elias; Chan Wing C; Gascoyne Randy D; Young Bryan D; Staudt Louis M; Lister T Andrew; Fitzgibbon Jude
Regions of acquired uniparental disomy at diagnosis of follicular lymphoma are associated with both overall survival and risk of transformation.
Blood 2009;113(10):2298-301.
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2009: Paulsson Kajsa; An Qian; Moorman Anthony V; Parker Helen; Molloy Gael; Davies Teresa; Griffiths Mike; Ross Fiona M; Irving Julie; Harrison Christine J; Young Bryan D; Strefford Jon C
Methylation of tumour suppressor gene promoters in the presence and absence of transcriptional silencing in high hyperdiploid acute lymphoblastic leukaemia.
British journal of haematology 2009;144(6):838-47.
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2009: Kearney Lyndal; Gonzalez De Castro David; Yeung Jenny; Procter Julia; Horsley Sharon W; Eguchi-Ishimae Minenori; Bateman Caroline M; Anderson Kristina; Chaplin Tracy; Young Bryan D; Harrison Christine J; Kempski Helena; So Chi Wai E; Ford Anthony M; Greaves Mel
Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia.
Blood 2009;113(3):646-8.
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2009: Gemenetzidis Emilios; Bose Amrita; Riaz Adeel M; Chaplin Tracy; Young Bryan D; Ali Muhammad; Sugden David; Thurlow Johanna K; Cheong Sok-Ching; Teo Soo-Hwang; Wan Hong; Waseem Ahmad; Parkinson Eric K; Fortune Farida; Teh Muy-Teck
FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation.
PloS one 2009;4(3):e4849.
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2009: Gupta Manu; Young Bryan D
Application of SNP genotype arrays to determine somatic changes in cancer.
Methods in molecular biology (Clifton, N.J.) 2009;538():179-206.
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2008: Mao Xin; Orchard Guy; Mitchell Tracey J; Oyama Noritaka; Russell-Jones Robin; Vermeer Maarten H; Willemze Rein; van Doorn Remko; Tensen Cornelis P; Young Bryan D; Whittaker Sean J
A genomic and expression study of AP-1 in primary cutaneous T-cell lymphoma: evidence for dysregulated expression of JUNB and JUND in MF and SS.
Journal of cutaneous pathology 2008;35(10):899-910.
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2008: Gupta Manu; Raghavan Manoj; Gale Rosemary E; Chelala Claude; Allen Christopher; Molloy Gael; Chaplin Tracy; Linch David C; Cazier Jean-Baptiste; Young Bryan D
Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia.
Genes, chromosomes & cancer 2008;47(9):729-39.
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2008: Raghavan Manoj; Smith Lan-Lan; Lillington Debra M; Chaplin Tracy; Kakkas Ioannis; Molloy Gael; Chelala Claude; Cazier Jean-Baptiste; Cavenagh James D; Fitzgibbon Jude; Lister T Andrew; Young Bryan D
Segmental uniparental disomy is a commonly acquired genetic event in relapsed acute myeloid leukemia.
Blood 2008;112(3):814-21.
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2008: Mao Xueying; Young Bryan D; Chaplin Tracy; Shipley Janet; Lu Yong-Jie
Subtle genomic alterations and genomic instability revealed in diploid cancer cell lines.
Cancer letters 2008;267(1):49-54.
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2008: Teh M T; Tilakaratne W M; Chaplin T; Young B D; Ariyawardana A; Pitiyage G; Lalli A; Stewart J E; Hagi-Pavli E; Cruchley A; Waseem A; Fortune F
Fingerprinting genomic instability in oral submucous fibrosis.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2008;37(7):430-6.
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2008: Noel Elodie E; Perry Jackie; Chaplin Tracy; Mao Xueying; Cazier Jean-Baptiste; Joel Simon P; Oliver R Tim D; Young Bryan D; Lu Yong-Jie
Identification of genomic changes associated with cisplatin resistance in testicular germ cell tumor cell lines.
Genes, chromosomes & cancer 2008;47(7):604-13.
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2008: Horsley Sharon W; Colman Susan; McKinley Mark; Bateman Caroline M; Jenney Meriel; Chaplin Tracy; Young Bryan D; Greaves Mel; Kearney Lyndal
Genetic lesions in a preleukemic aplasia phase in a child with acute lymphoblastic leukemia.
Genes, chromosomes & cancer 2008;47(4):333-40.
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2008: Harada T; Chelala C; Bhakta V; Chaplin T; Caulee K; Baril P; Young B D; Lemoine N R
Genome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays.
Oncogene 2008;27(13):1951-60.
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2007: Fitzgibbon J; Iqbal S; Davies A; O'shea D; Carlotti E; Chaplin T; Matthews J; Raghavan M; Norton A; Lister T A; Young B D
Genome-wide detection of recurring sites of uniparental disomy in follicular and transformed follicular lymphoma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(7):1514-20.
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2007: Mao Xueying; James Sharon Y; Yáñez-Muñoz Rafael J; Chaplin Tracy; Molloy Gael; Oliver R Tim D; Young Bryan D; Lu Yong-Jie
Rapid high-resolution karyotyping with precise identification of chromosome breakpoints.
Genes, chromosomes & cancer 2007;46(7):675-83.
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2007: Purdie Karin J; Lambert Sally R; Teh Muy-Teck; Chaplin Tracy; Molloy Gael; Raghavan Manoj; Kelsell David P; Leigh Irene M; Harwood Catherine A; Proby Charlotte M; Young Bryan D
Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis.
Genes, chromosomes & cancer 2007;46(7):661-9.
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2007: Mao Xueying; Young Bryan D; Lu Yong-Jie
The application of single nucleotide polymorphism microarrays in cancer research.
Current genomics 2007;8(4):219-28.
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2007: Debernardi S; Skoulakis S; Molloy G; Chaplin T; Dixon-McIver A; Young B D
MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(5):912-6.
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2007: Summers K; Stevens J; Kakkas I; Smith M; Smith L L; Macdougall F; Cavenagh J; Bonnet D; Young B D; Lister T A; Fitzgibbon J
Wilms' tumour 1 mutations are associated with FLT3-ITD and failure of standard induction chemotherapy in patients with normal karyotype AML.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(3):550-1; author reply 552.
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2006: Dunne J; Cullmann C; Ritter M; Soria N Martinez; Drescher B; Debernardi S; Skoulakis S; Hartmann O; Krause M; Krauter J; Neubauer A; Young B D; Heidenreich O
siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.
Oncogene 2006;25(45):6067-78.
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2006: Mao Xin; Orchard Guy; Vonderheid Eric C; Nowell Peter C; Bagot Martine; Bensussan Armand; Russell-Jones Robin; Young Bryan D; Whittaker Sean J
Heterogeneous abnormalities of CCND1 and RB1 in primary cutaneous T-Cell lymphomas suggesting impaired cell cycle control in disease pathogenesis.
The Journal of investigative dermatology 2006;126(6):1388-95.
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2006: Strefford Jon C; van Delft Frederik W; Robinson Hazel M; Worley Helen; Yiannikouris Olga; Selzer Rebecca; Richmond Todd; Hann Ian; Bellotti Tony; Raghavan Manoj; Young Bryan D; Saha Vaskar; Harrison Christine J
Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8167-72.
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2006: Young Bryan D; Debernardi Silvana; Lillington Debra M; Skoulakis Spyros; Chaplin Tracy; Foot Nicola J; Raghavan Manoj
A role for mitotic recombination in leukemogenesis.
Advances in enzyme regulation 2006;46():90-7.
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2006: Strefford J C; Lane T M; Hill A; LeRoux L; Foot N J; Shipley J; Oliver R T D; Lu Y-J; Young B D
Molecular characterisation of the t(1;15)(p22;q22) translocation in the prostate cancer cell line LNCaP.
Cytogenetic and genome research 2006;112(1-2):45-52.
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2005: Fitzgibbon Jude; Smith Lan-Lan; Raghavan Manoj; Smith Matthew L; Debernardi Silvana; Skoulakis Spyros; Lillington Debra; Lister T Andrew; Young Bryan D
Association between acquired uniparental disomy and homozygous gene mutation in acute myeloid leukemias.
Cancer research 2005;65(20):9152-4.
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2005: Lu Yong-Jie; Yang Jinshu; Noel Elodie; Skoulakis Spyros; Chaplin Tracy; Raghavan Manoj; Purkis Trisha; McIntyre Alan; Kudahetti Sakunthala C; Naase Mahmoud; Berney Dan; Shipley Janet; Oliver R Timothy D; Young Bryan D
Association between large-scale genomic homozygosity without chromosomal loss and nonseminomatous germ cell tumor development.
Cancer research 2005;65(20):9137-41.
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2005: Teh Muy-Teck; Blaydon Diana; Chaplin Tracy; Foot Nicola J; Skoulakis Spyros; Raghavan Manoj; Harwood Catherine A; Proby Charlotte M; Philpott Michael P; Young Bryan D; Kelsell David P
Genomewide single nucleotide polymorphism microarray mapping in basal cell carcinomas unveils uniparental disomy as a key somatic event.
Cancer research 2005;65(19):8597-603.
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2005: van Delft Frederik W; Bellotti Tony; Luo Zhiyuan; Jones Louise K; Patel Naina; Yiannikouris Olga; Hill Alex S; Hubank Mike; Kempski Helena; Fletcher Danielle; Chaplin Tracy; Foot Nicola; Young Bryan D; Hann Ian M; Gammerman Alex; Saha Vaskar
Prospective gene expression analysis accurately subtypes acute leukaemia in children and establishes a commonality between hyperdiploidy and t(12;21) in acute lymphoblastic leukaemia.
British journal of haematology 2005;130(1):26-35.
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2005: Wilson Charlotte; Yang Jinshu; Strefford Jon C; Summersgill Brenda; Young Bryan D; Shipley Janet; Oliver Tim; Lu Yong-Jie
Overexpression of genes on 16q associated with cisplatin resistance of testicular germ cell tumor cell lines.
Genes, chromosomes & cancer 2005;43(2):211-6.
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2005: Strefford Jon C; Stasevich Irina; Lane Tim M; Lu Yong-Jie; Oliver Tim; Young Bryan D
A combination of molecular cytogenetic analyses reveals complex genetic alterations in conventional renal cell carcinoma.
Cancer genetics and cytogenetics 2005;159(1):1-9.
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2005: Kelsell David P; Norgett Elizabeth E; Unsworth Harriet; Teh Muy-Teck; Cullup Thomas; Mein Charles A; Dopping-Hepenstal Patricia J; Dale Beverly A; Tadini Gianluca; Fleckman Philip; Stephens Karen G; Sybert Virginia P; Mallory Susan B; North Bernard V; Witt David R; Sprecher Eli; Taylor Aileen E M; Ilchyshyn Andrew; Kennedy Cameron T; Goodyear Helen; Moss Celia; Paige David; Harper John I; Young Bryan D; Leigh Irene M; Eady Robin A J; O'Toole Edel A
Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis.
American journal of human genetics 2005;76(5):794-803.
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2005: Raghavan Manoj; Lillington Debra M; Skoulakis Spyros; Debernardi Silvana; Chaplin Tracy; Foot Nicola J; Lister T Andrew; Young Bryan D
Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias.
Cancer research 2005;65(2):375-8.
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2004: Mao X; Orchard G; Lillington D M; Child F J; Vonderheid E C; Nowell P C; Bagot M; Bensussan A; Russell-Jones R; Young B D; Whittaker S J
BCL2 and JUNB abnormalities in primary cutaneous lymphomas.
The British journal of dermatology 2004;151(3):546-56.
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2004: Debernardi Silvana; Lillington Debra; Young Bryan D
Understanding cancer at the chromosome level: 40 years of progress.
European journal of cancer (Oxford, England : 1990) 2004;40(13):1960-7.
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2004: Woodfine Kathryn; Fiegler Heike; Beare David M; Collins John E; McCann Owen T; Young Bryan D; Debernardi Silvana; Mott Richard; Dunham Ian; Carter Nigel P
Replication timing of the human genome.
Human molecular genetics 2004;13(2):191-202.
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2004: Liu Wai M; Strauss Sandra J; Chaplin Tracy; Shahin Sipra; Propper David J; Young Bryan D; Joel Simon P; Malpas James S
s-thalidomide has a greater effect on apoptosis than angiogenesis in a multiple myeloma cell line.
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5(3):247-54.
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2003: Hill Alexander S; MacCallum Peter K; Young Bryan D; Lillington Debra M
Molecular cloning of a constitutional t(7;22) translocation associated with risk of hematological malignancy.
Genes, chromosomes & cancer 2003;38(3):260-4.
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2003: Mao Xin; Onadim Zerrin; Price Elizabeth A; Child Fiona; Lillington Debra M; Russell-Jones Robin; Young Bryan D; Whittaker Sean
Genomic alterations in blastic natural killer/extranodal natural killer-like T cell lymphoma with cutaneous involvement.
The Journal of investigative dermatology 2003;121(3):618-27.
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2003: Mao Xin; Orchard Guy; Lillington Debra M; Russell-Jones Robin; Young Bryan D; Whittaker Sean
Genetic alterations in primary cutaneous CD30+ anaplastic large cell lymphoma.
Genes, chromosomes & cancer 2003;37(2):176-85.
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2003: Debernardi Silvana; Lillington Debra M; Chaplin Tracy; Tomlinson Simon; Amess John; Rohatiner Ama; Lister T Andrew; Young Bryan D
Genome-wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation-mediated fusion events.
Genes, chromosomes & cancer 2003;37(2):149-58.
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2003: Chambers A E; Banerjee S; Chaplin T; Dunne J; Debernardi S; Joel S P; Young B D
Histone acetylation-mediated regulation of genes in leukaemic cells.
European journal of cancer (Oxford, England : 1990) 2003;39(8):1165-75.
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2003: Mao Xin; Lillington Debra M; Czepulkowski Barbara; Russell-Jones Robin; Young Bryan D; Whittaker Sean
Molecular cytogenetic characterization of Sézary syndrome.
Genes, chromosomes & cancer 2003;36(3):250-60.
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2003: Lillington Debra M; Kingston Judith E; Coen Pietro G; Price Elizabeth; Hungerford John; Domizio Paola; Young Bryan D; Onadim Zerrin
Comparative genomic hybridization of 49 primary retinoblastoma tumors identifies chromosomal regions associated with histopathology, progression, and patient outcome.
Genes, chromosomes & cancer 2003;36(2):121-8.
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2003: Mao Xin; Orchard Guy; Lillington Debra M; Russell-Jones Robin; Young Bryan D; Whittaker Sean J
Amplification and overexpression of JUNB is associated with primary cutaneous T-cell lymphomas.
Blood 2003;101(4):1513-9.
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2003: Dunne Jenny; Drescher Bettina; Riehle Heidemarie; Hadwiger Philipp; Young Bryan D; Krauter Jürgen; Heidenreich Olaf
The apparent uptake of fluorescently labeled siRNAs by electroporated cells depends on the fluorochrome.
Oligonucleotides 2003;13(5):375-80.
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2002: Lillington D M; Goff L K; Kingston J E; Onadim Z; Price E; Domizio P; Young B D
High level amplification of N-MYC is not associated with adverse histology or outcome in primary retinoblastoma tumours.
British journal of cancer 2002;87(7):779-82.
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2002: Van Trappen P O; Ryan A; Carroll M; Lecoeur C; Goff L; Gyselman V G; Young B D; Lowe D G; Pepper M S; Shepherd J H; Jacobs I J
A model for co-expression pattern analysis of genes implicated in angiogenesis and tumour cell invasion in cervical cancer.
British journal of cancer 2002;87(5):537-44.
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2002: Jenner Michael J; Summers Karin E; Norton Andrew J; Amess John A; Arch Rachael S; Young Bryan D; Lister T Andrew; Fitzgibbon Jude; Goff Lindsey K
JH probe real-time quantitative polymerase chain reaction assay for Bcl-2/IgH rearrangements.
British journal of haematology 2002;118(2):550-8.
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2002: Strefford Jon C; Lillington Debra M; Steggall Martin; Lane Tim M; Nouri A M E; Young Bryan D; Oliver R T D
Novel chromosome findings in bladder cancer cell lines detected with multiplex fluorescence in situ hybridization.
Cancer genetics and cytogenetics 2002;135(2):139-46.
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2002: Debernardi Silvana; Bassini Alessandra; Jones Louise K; Chaplin Tracy; Linder Britta; de Bruijn Diederik R H; Meese Eckart; Young Bryan D
The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex.
Blood 2002;99(1):275-81.
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2002: Dalley Christopher D; Neat Michael J; Foot Nicola J; Burridge Margaret; Byrne Loretta; Amess John A; Rohatiner Ama Z S; Lister Andrew; Young Bryan D; Lillington Debra M
Comparative genomic hybridization and multiplex-fluorescence in situ hybridization: an appraisal in elderly patients with acute myelogenous leukemia.
The hematology journal : the official journal of the European Haematology Association / EHA 2002;3(6):290-8.
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2002: Lillington D M; Micallef I N M; Carpenter E; Neat M J; Amess J A L; Matthews J; Foot N J; Lister T A; Young B D; Rohatiner A Z S
Genetic susceptibility to Hodgkin's disease and secondary neoplasias: FISH analysis reveals patients at high risk of developing secondary neoplasia.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2002;13 Suppl 1():40-3.
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2001: Mao X; Lillington D M; Czepulkowski B; Young B D; Russell-Jones R; Whittaker S
A case of adult T-cell leukaemia/lymphoma characterized by multiplex-fluorescence in situ hybridization, comparative genomic hybridization, fluorescence in situ hybridization and cytogenetics.
The British journal of dermatology 2001;145(1):117-22.
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2001: Jones L K; Chaplin T; Shankar A; Neat M; Patel N; Samuel D P; Hill A S; Debernardi S; Bassini A; Young B D; Saha V
Identification and molecular characterisation of a CALM-AF10 fusion in acute megakaryoblastic leukaemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(6):910-4.
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2001: de Bruijn D R; dos Santos N R; Thijssen J; Balemans M; Debernardi S; Linder B; Young B D; Geurts van Kessel A
The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10.
Oncogene 2001;20(25):3281-9.
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2001: Lillington D M; Micallef I N; Carpenter E; Neat M J; Amess J A; Matthews J; Foot N J; Young B D; Lister T A; Rohatiner A Z
Detection of chromosome abnormalities pre-high-dose treatment in patients developing therapy-related myelodysplasia and secondary acute myelogenous leukemia after treatment for non-Hodgkin's lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(9):2472-81.
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2001: Chaplin T; Jones L; Debernardi S; Hill A S; Lillington D M; Young B D
Molecular analysis of the genomic inversion and insertion of AF10 into MLL suggests a single-step event.
Genes, chromosomes & cancer 2001;30(2):175-80.
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2001: Strefford J C; Lillington D M; Young B D; Oliver R T
The use of multicolor fluorescence technologies in the characterization of prostate carcinoma cell lines: a comparison of multiplex fluorescence in situ hybridization and spectral karyotyping data.
Cancer genetics and cytogenetics 2001;124(2):112-21.
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2001: Strefford J C; Foot N J; Chaplin T; Neat M J; Oliver R T; Young B D; Jones L K
The characterisation of the lymphoma cell line U937, using comparative genomic hybridisation and multi-plex FISH.
Cytogenetics and cell genetics 2001;94(1-2):9-14.
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2000: Lillington D M; Jaju R J; Shankar A G; Neat M; Kearney L; Young B D; Saha V
Cytogenetic and molecular evidence of marrow involvement in extramedullary acute myeloid leukaemia.
British journal of haematology 2000;110(3):547-51.
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2000: Hill A S; Foot N J; Chaplin T L; Young B D
The most frequent constitutional translocation in humans, the t(11;22)(q23;q11) is due to a highly specific alu-mediated recombination.
Human molecular genetics 2000;9(10):1525-32.
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2000: Linder B; Newman R; Jones L K; Debernardi S; Young B D; Freemont P; Verrijzer C P; Saha V
Biochemical analyses of the AF10 protein: the extended LAP/PHD-finger mediates oligomerisation.
Journal of molecular biology 2000;299(2):369-78.
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1999: McCullagh P; Chaplin T; Meerabux J; Grenzelias D; Lillington D; Poulsom R; Gregorini A; Saha V; Young B D
The cloning, mapping and expression of a novel gene, BRL, related to the AF10 leukaemia gene.
Oncogene 1999;18(52):7442-52.
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1999: Bigoni R; Cuneo A; Roberti M G; Moretti S; De Angeli C; Dabusti M; Campioni D; del Senno L; Biondi A; Chaplin T; Young B D; Castoldi G
Therapy-related adult acute lymphoblastic leukemia with t(4;11)(q21; q23): MLL rearrangement, p53 mutation and multilineage involvement.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(5):704-7.
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1999: Lecointe N; Meerabux J; Ebihara M; Hill A; Young B D
Molecular analysis of an unstable genomic region at chromosome band 11q23 reveals a disruption of the gene encoding the alpha2 subunit of platelet-activating factor acetylhydrolase (Pafah1a2) in human lymphoma.
Oncogene 1999;18(18):2852-9.
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1998: Gregorini A; Cinti C; Young B D
Molecular abnormalities in leukemia: the 11q23 story so far.
Journal of biological regulators and homeostatic agents 1998;12(4):95-105.
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1998: Pappa V I; Wilkes S; Salam A; Young B D; Lister T A; Rohatiner A Z
Use of the polymerase chain reaction and direct sequencing analysis to detect cells with the t(14;18) in autologous bone marrow from patients with follicular lymphoma, before and after in vitro treatment.
Bone marrow transplantation 1998;22(6):553-8.
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1998: Lillington D M; Young B D; Berger R; Martineau M; Moorman A V; Secker-Walker L M
The t(10;11)(p12;q23) translocation in acute leukaemia: a cytogenetic and clinical study of 20 patients. European 11q23 Workshop participants.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(5):801-4.
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1998: Saha V; Young B D; Freemont P S
Translocations, fusion genes, and acute leukemia.
Journal of cellular biochemistry. Supplement 1998;30-31():264-76.
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1996: Gregorini A; Sahin F I; Lillington D M; Meerabux J; Saha V; McCullagh P; Bocci M; Menevse S; Papa S; Young B D
Gene BR140, which is related to AF10 and AF17, maps to chromosome band 3p25.
Genes, chromosomes & cancer 1996;17(4):269-72.
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1996: Dyer M J; Lillington D M; Bastard C; Tilly H; Lens D; Heward J M; Stranks G; Morilla R; Monrad S; Guglielmi P; Kluin-Nelemans J C; Hagemeijer A; Young B D; Catovsky D
Concurrent activation of MYC and BCL2 in B cell non-Hodgkin lymphoma cell lines by translocation of both oncogenes to the same immunoglobulin heavy chain locus.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1996;10(7):1198-208.
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1996: Meerabux J; Yaspo M L; Roebroek A J; Van de Ven W J; Lister T A; Young B D
A new member of the proprotein convertase gene family (LPC) is located at a chromosome translocation breakpoint in lymphomas.
Cancer research 1996;56(3):448-51.
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1995: Saha V; Lillington D M; Shelling A N; Chaplin T; Yaspo M L; Ganesan T S; Young B D
AF6 gene on chromosome band 6q27 maps distal to the minimal region of deletion in epithelial ovarian cancer.
Genes, chromosomes & cancer 1995;14(3):220-2.
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1995: Beverloo H B; Le Coniat M; Wijsman J; Lillington D M; Bernard O; de Klein A; van Wering E; Welborn J; Young B D; Hagemeijer A
Breakpoint heterogeneity in t(10;11) translocation in AML-M4/M5 resulting in fusion of AF10 and MLL is resolved by fluorescent in situ hybridization analysis.
Cancer research 1995;55(19):4220-4.
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1995: Saha V; Chaplin T; Gregorini A; Ayton P; Young B D
The leukemia-associated-protein (LAP) domain, a cysteine-rich motif, is present in a wide range of proteins, including MLL, AF10, and MLLT6 proteins.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9737-41.
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1995: Chaplin T; Bernard O; Beverloo H B; Saha V; Hagemeijer A; Berger R; Young B D
The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene.
Blood 1995;86(6):2073-6.
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1995: Shamash J; Davies D C; Salam A; Rohatiner A Z; Young B D; Lister T A
Induction of CD80 expression in low-grade B cell lymphoma--a potential immunotherapeutic target.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(8):1349-52.
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1995: Chaplin T; Ayton P; Bernard O A; Saha V; Della Valle V; Hillion J; Gregorini A; Lillington D; Berger R; Young B D
A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia.
Blood 1995;85(6):1435-41.
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1994: Bower M; Parry P; Carter M; Lillington D M; Amess J; Lister T A; Evans G; Young B D
Prevalence and clinical correlations of MLL gene rearrangements in AML-M4/5.
Blood 1994;84(11):3776-80.
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1994: Lastowska M A; Lillington D M; Shelling A N; Cooke I; Gibbons B; Young B D; Ganesan T S
Fluorescence in situ hybridization analysis using cosmid probes to define chromosome 6q abnormalities in ovarian carcinoma cell lines.
Cancer genetics and cytogenetics 1994;77(2):99-105.
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1994: Gibbons B; Lillington D M; Monard S; Young B D; Cheung K L; Lister T A; Kearney L
Fluorescence in situ hybridisation studies to characterise complete and partial monosomy 7 in myeloid disorders.
Genes, chromosomes & cancer 1994;10(4):244-9.
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1994: Lillington D M; Monard S; Johnson P W; Evans M L; Kearney L U; Lister T A; Young B D; Gibbons B
The t(14;18) in a patient with de novo acute lymphoblastic leukemia is associated with t(8;9).
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994;8(4):560-3.
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1994: Johnson P W; Price C G; Smith T; Cotter F E; Meerabux J; Rohatiner A Z; Young B D; Lister T A
Detection of cells bearing the t(14;18) translocation following myeloablative treatment and autologous bone marrow transplantation for follicular lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(4):798-805.
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1994: Meerabux J M; Cotter F E; Kearney L; Nizetic D; Dhut S; Gibbons B; Lister T A; Young B D
Molecular cloning of a novel 11q23 breakpoint associated with non-Hodgkin's lymphoma.
Oncogene 1994;9(3):893-8.
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1994: Bower M; Parry P; Gibbons B; Amess J; Lister T A; Young B D; Evans G A
Human trithorax gene rearrangements in therapy-related acute leukaemia after etoposide treatment.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994;8(2):226-9.
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1993: Tuszynski A; Dhut S; Young B D; Lister T A; Rohatiner A Z; Amess J A; Chaplin T; Dorey E; Gibbons B
Detection and significance of bcr-abl mRNA transcripts and fusion proteins in Philadelphia-positive adult acute lymphoblastic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1993;7(10):1504-8.
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1993: Bower M; Chaplin T; Das S; Kearney L; Gibbons B; Riley J H; Lister T A; Young B D
The isolation of a yeast artificial chromosome which spans the chromosome 11q23 region involved in a number of translocations in acute leukaemias.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1993;7 Suppl 2():S34-9.
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1993: Nacheva E; Kearney L; Bower M; Chaplin T; Douek E; Das S; Young B D
In situ hybridisation analysis of a homogeneously staining region at 11q23-24 in an acute myeloid leukaemia (M5) using yeast artificial chromosomes.
Genes, chromosomes & cancer 1993;7(3):123-7.
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1993: Parry P; Djabali M; Bower M; Khristich J; Waterman M; Gibbons B; Young B D; Evans G
Structure and expression of the human trithorax-like gene 1 involved in acute leukemias.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(10):4738-42.
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1993: Melo J V; Gordon D E; Tuszynski A; Dhut S; Young B D; Goldman J M
Expression of the ABL-BCR fusion gene in Philadelphia-positive acute lymphoblastic leukemia.
Blood 1993;81(10):2488-91.
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1992: Das S; Kearney L; Bower M; Chaplin T; Riley J H; Anand R; Young B D
Molecular cloning and analysis of chromosome band 11q23 involved in leukaemia-associated translocations.
Genes, chromosomes & cancer 1992;5(3):244-51.
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1992: Young B D
Cytogenetic and molecular analysis of chromosome 11q23 abnormalities in leukaemia.
Baillière's clinical haematology 1992;5(4):881-95.
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1992: Djabali M; Selleri L; Parry P; Bower M; Young B D; Evans G A
A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias.
Nature genetics 1992;2(2):113-8.
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1992: Suijkerbuijk R F; Matthopoulos D; Kearney L; Monard S; Dhut S; Cotter F E; Herbergs J; van Kessel A G; Young B D
Fluorescent in situ identification of human marker chromosomes using flow sorting and Alu element-mediated PCR.
Genomics 1992;13(2):355-62.
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1992: Gupta R K; Whelan J S; Lister T A; Young B D; Bodmer J G
Direct sequence analysis of the t(14;18) chromosomal translocation in Hodgkin's disease.
Blood 1992;79(8):2084-8.
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1991: Limpens J; de Jong D; van Krieken J H; Price C G; Young B D; van Ommen G J; Kluin P M
Bcl-2/JH rearrangements in benign lymphoid tissues with follicular hyperplasia.
Oncogene 1991;6(12):2271-6.
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1991: Kearney L; Watkins P C; Young B D; Sacchi N
DNA sequences of chromosome 21-specific YAC detect the t(8;21) breakpoint of acute myelogenous leukemia.
Cancer genetics and cytogenetics 1991;57(1):109-19.
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1991: Price C G; Meerabux J; Murtagh S; Cotter F E; Rohatiner A Z; Young B D; Lister T A
The significance of circulating cells carrying t(14;18) in long remission from follicular lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(9):1527-32.
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1991: Dhut S; Chaplin T; Young B D
Normal c-abl gene protein--a nuclear component.
Oncogene 1991;6(8):1459-64.
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1991: Price C G; Tuszynski A; Watt S M; Murdoch S J; Lister T A; Young B D
Detection of additional JH/BCL2 translocations in follicular lymphoma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1991;5(7):548-54.
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1991: Cotter F E; Das S; Douek E; Carter N P; Young B D
The generation of DNA probes to chromosome 11q23 by Alu PCR on small numbers of flow-sorted 22q- derivative chromosomes.
Genomics 1991;9(3):473-80.
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1991: Cotter F E; Price C; Meerabux J; Zucca E; Young B D
Direct sequence analysis of 14q+ and 18q- chromosome junctions at the MBR and MCR revealing clustering within the MBR in follicular lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1991;2 Suppl 2():93-7.
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1991: Cotter F E; Lillington D; Hampton G; Riddle P; Nasipuri S; Gibbons B; Young B D
Gene mapping by microdissection and enzymatic amplification: heterogeneity in leukaemia associated breakpoints on chromosome 11.
Genes, chromosomes & cancer 1991;3(1):8-15.
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1991: Dhut S; Gibbons B; Chaplin T; Young B D
Establishment of a lymphoblastoid cell line, SD-1, expressing the p190 bcr-abl chimaeric protein.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1991;5(1):49-55.
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1991: Das S; Cotter F E; Gibbons B; Dhut S; Young B D
CD3G is within 200 kb of the leukemic t(4;11) translocation breakpoint.
Genes, chromosomes & cancer 1991;3(1):44-7.
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1990: Dhut S; Chaplin T; Young B D
BCR-ABL and BCR proteins: biochemical characterization and localization.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1990;4(11):745-50.
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1990: Betts D R; Kingston J E; Dorey E L; Young B D; Webb D; Katz F E; Gibbons B
Monosomy 20: a nonrandom finding in childhood acute lymphoblastic leukemia.
Genes, chromosomes & cancer 1990;2(3):182-5.
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1990: Cotter F E; Hampton G M; Nasipuri S; Bodmer W F; Young B D
Rapid isolation of human chromosome-specific DNA probes from a somatic cell hybrid.
Genomics 1990;7(2):257-63.
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1990: Cotter F E; Price C; Young B D; Lister T A
Minimal residual disease in leukaemia and lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1990;1(3):167-70.
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1989: Cotter F; Nasipuri S; Lam G; Young B D
Gene mapping by enzymatic amplification from flow-sorted chromosomes.
Genomics 1989;5(3):470-4.
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1989: Price C G; Cotter F E; Curling O M; D'Ardenne A J; Rohatiner A Z; Young B D; Lister T A
Polymerase chain reaction to confirm extranodal progression of follicular lymphoma.
Lancet 1989;1(8647):1132.
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1988: Young B D
Molecular analysis of Philadelphia chromosome positive leukaemias.
The British journal of cancer. Supplement 1988;9():58-61.
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1988: Dhut S; Dorey E L; Horton M A; Ganesan T S; Young B D
Identification of two normal bcr gene products in the cytoplasm.
Oncogene 1988;3(5):561-6.
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1987: Walker L C; Ganesan T S; Dhut S; Gibbons B; Lister T A; Rothbard J; Young B D
Novel chimaeric protein expressed in Philadelphia positive acute lymphoblastic leukaemia.
Nature 1987;329(6142):851-3.
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