Joanne Young

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Herath Nirmitha I; Purdie David M; Kew Michael C; Smith Jeffery L; Young Joanne; Leggett Barbara A; MacDonald Graeme A
Varying etiologies lead to different molecular changes in Australian and South African hepatocellular carcinomas.
Poynter Jenny N; Haile Robert W; Siegmund Kimberly D; Campbell Peter T; Figueiredo Jane C; Limburg Paul; Young Joanne; Le Marchand Loic; Potter John D; Cotterchio Michelle; Casey Graham; Hopper John L; Jenkins Mark A; Thibodeau Stephen N; Newcomb Polly A; Baron John A;
Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status.
Kominami K; Nagasaka T; Cullings H M; Hoshizima N; Sasamoto H; Young J; Leggett B A; Tanaka N; Matsubara N
Methylation in p14(ARF) is frequently observed in colorectal cancer with low-level microsatellite instability.

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2009: Herath Nirmitha I; Purdie David M; Kew Michael C; Smith Jeffery L; Young Joanne; Leggett Barbara A; MacDonald Graeme A
Varying etiologies lead to different molecular changes in Australian and South African hepatocellular carcinomas.
International journal of oncology 2009;35(5):1081-9.
2009: Poynter Jenny N; Haile Robert W; Siegmund Kimberly D; Campbell Peter T; Figueiredo Jane C; Limburg Paul; Young Joanne; Le Marchand Loic; Potter John D; Cotterchio Michelle; Casey Graham; Hopper John L; Jenkins Mark A; Thibodeau Stephen N; Newcomb Polly A; Baron John A;
Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(10):2745-50.
2009: Kominami K; Nagasaka T; Cullings H M; Hoshizima N; Sasamoto H; Young J; Leggett B A; Tanaka N; Matsubara N
Methylation in p14(ARF) is frequently observed in colorectal cancer with low-level microsatellite instability.
The Journal of international medical research 2009;37(4):1038-45.
2009: Nakagawa Hitoshi; Nagasaka Takeshi; Cullings Harry M; Notohara Kenji; Hoshijima Naoko; Young Joanne; Lynch Henry T; Tanaka Noriaki; Matsubara Nagahide
Efficient molecular screening of Lynch syndrome by specific 3' promoter methylation of the MLH1 or BRAF mutation in colorectal cancer with high-frequency microsatellite instability.
Oncology reports 2009;21(6):1577-83.
2009: Loddo M; Kingsbury S R; Rashid M; Proctor I; Holt C; Young J; El-Sheikh S; Falzon M; Eward K L; Prevost T; Sainsbury R; Stoeber K; Williams G H
Cell-cycle-phase progression analysis identifies unique phenotypes of major prognostic and predictive significance in breast cancer.
British journal of cancer 2009;100(6):959-70.
2008: Poynter Jenny N; Siegmund Kimberly D; Weisenberger Daniel J; Long Tiffany I; Thibodeau Stephen N; Lindor Noralane; Young Joanne; Jenkins Mark A; Hopper John L; Baron John A; Buchanan Dan; Casey Graham; Levine A Joan; Le Marchand Loïc; Gallinger Steven; Bapat Bharati; Potter John D; Newcomb Polly A; Haile Robert W; Laird Peter W;
Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(11):3208-15.
2007: Poynter Jenny N; Figueiredo Jane C; Conti David V; Kennedy Kathleen; Gallinger Steven; Siegmund Kimberly D; Casey Graham; Thibodeau Stephen N; Jenkins Mark A; Hopper John L; Byrnes Graham B; Baron John A; Goode Ellen L; Tiirikainen Maarit; Lindor Noralane; Grove John; Newcomb Polly; Jass Jeremy; Young Joanne; Potter John D; Haile Robert W; Duggan David J; Le Marchand Loic;
Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry.
Cancer research 2007;67(23):11128-32.
2007: Herath Nirmitha I; Walsh Michael D; Kew Michael; Smith Jeffery L; Jass Jeremy R; Young Joanne; Leggett Barbara A; Macdonald Graeme A
Silencing of O6-methylguanine DNA methyltransferase in the absence of promoter hypermethylation in hepatocellular carcinomas from Australia and South Africa.
Oncology reports 2007;17(4):817-22.
2007: Widschwendter Martin; Fiegl Heidi; Egle Daniel; Mueller-Holzner Elisabeth; Spizzo Gilbert; Marth Christian; Weisenberger Daniel J; Campan Mihaela; Young Joanne; Jacobs Ian; Laird Peter W
Epigenetic stem cell signature in cancer.
Nature genetics 2007;39(2):157-8.
2007: Jaskowski Lesley; Young Joanne; Jackson Leigh; Arnold Sven; Barker Melissa A; Walsh Michael D; Buchanan Daniel D; Holman Samantha; Mensink Kara A; Jenkins Mark A; Hopper John L; Thibodeau Stephen N; Jass Jeremy R; Spurdle Amanda B
Stability of BAT26 in Lynch syndrome colorectal tumours.
European journal of human genetics : EJHG 2007;15(2):139-41; author reply 141-2.
2006: Spring Kevin J; Zhao Zhen Zhen; Karamatic Rozemary; Walsh Michael D; Whitehall Vicki L J; Pike Tanya; Simms Lisa A; Young Joanne; James Michael; Montgomery Grant W; Appleyard Mark; Hewett David; Togashi Kazutomo; Jass Jeremy R; Leggett Barbara A
High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy.
Gastroenterology 2006;131(5):1400-7.
2006: Chow Elizabeth; Lipton Lara; Lynch Elly; D'Souza Rebecca; Aragona Clelia; Hodgkin Lindy; Brown Gregor; Winship Ingrid; Barker Melissa; Buchanan Daniel; Cowie Shannon; Nasioulas Steve; du Sart Desiree; Young Joanne; Leggett Barbara; Jass Jeremy; Macrae Finlay
Hyperplastic polyposis syndrome: phenotypic presentations and the role of MBD4 and MYH.
Gastroenterology 2006;131(1):30-9.
2006: Weisenberger Daniel J; Siegmund Kimberly D; Campan Mihaela; Young Joanne; Long Tiffany I; Faasse Mark A; Kang Gyeong Hoon; Widschwendter Martin; Weener Deborah; Buchanan Daniel; Koh Hoey; Simms Lisa; Barker Melissa; Leggett Barbara; Levine Joan; Kim Myungjin; French Amy J; Thibodeau Stephen N; Jass Jeremy; Haile Robert; Laird Peter W
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.
Nature genetics 2006;38(7):787-93.
2006: Wynter Coral V A; Kambara Takeshi; Walsh Michael D; Leggett Barbara A; Young Joanne; Jass Jeremy R
DNA methylation patterns in adenomas from FAP, multiple adenoma and sporadic colorectal carcinoma patients.
International journal of cancer. Journal international du cancer 2006;118(4):907-15.
2006: Simpson Fiona; Lammerts van Bueren Kelly; Butterfield Natalie; Bennetts Jennifer S; Bowles Josephine; Adolphe Christelle; Simms Lisa A; Young Joanne; Walsh Michael D; Leggett Barbara; Fowles Lindsay F; Wicking Carol
The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b.
Experimental cell research 2006;312(1):73-85.
2006: Chia June A; Simms Lisa A; Cozzi Sarah-Jane; Young Joanne; Jass Jeremy R; Walsh Michael D; Spring Kevin J; Leggett Barbara A; Whitehall Vicki L J
SnoN expression is differently regulated in microsatellite unstable compared with microsatellite stable colorectal cancers.
BMC cancer 2006;6():252.
2005: Gill Sharlene; Lindor Noralane M; Burgart Lawrence J; Smalley Regenia; Leontovich Olga; French Amy J; Goldberg Richard M; Sargent Daniel J; Jass Jeremy R; Hopper John L; Jenkins Mark A; Young Joanne; Barker Melissa A; Walsh Michael D; Ruszkiewicz Andrew R; Thibodeau Stephen N
Isolated loss of PMS2 expression in colorectal cancers: frequency, patient age, and familial aggregation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(18):6466-71.
2005: Young Joanne; Barker Melissa A; Simms Lisa A; Walsh Michael D; Biden Kelli G; Buchanan Daniel; Buttenshaw Ron; Whitehall Vicki L J; Arnold Sven; Jackson Leigh; Kambara Takeshi; Spring Kevin J; Jenkins Mark A; Walker Graeme J; Hopper John L; Leggett Barbara A; Jass Jeremy R
Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2005;3(3):254-63.
2004: Nagasaka Takeshi; Sasamoto Hiromi; Notohara Kenji; Cullings Harry M; Takeda Masanori; Kimura Keigo; Kambara Takeshi; MacPhee Donald G; Young Joanne; Leggett Barbara A; Jass Jeremy R; Tanaka Noriaki; Matsubara Nagahide
Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(22):4584-94.
2004: Kambara T; Simms L A; Whitehall V L J; Spring K J; Wynter C V A; Walsh M D; Barker M A; Arnold S; McGivern A; Matsubara N; Tanaka N; Higuchi T; Young J; Jass J R; Leggett B A
BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum.
Gut 2004;53(8):1137-44.
2004: Herath Nirmitha I; Walsh Michael D; Kew Michael C; Young Joanne; Leggett Barbara A; Macdonald Graeme A
Cadherin/catenin complex appears to be intact in hepatocellular carcinomas from Australia and South Africa.
Journal of gastroenterology and hepatology 2004;19(6):676-82.
2004: Mori Yuriko; Yin Jing; Sato Fumiaki; Sterian Anca; Simms Lisa A; Selaru Florin M; Schulmann Karsten; Xu Yan; Olaru Andreea; Wang Suna; Deacu Elena; Abraham John M; Young Joanne; Leggett Barbara A; Meltzer Stephen J
Identification of genes uniquely involved in frequent microsatellite instability colon carcinogenesis by expression profiling combined with epigenetic scanning.
Cancer research 2004;64(7):2434-8.
2004: Wynter C V A; Walsh M D; Higuchi T; Leggett B A; Young J; Jass J R
Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer.
Gut 2004;53(4):573-80.
2004: McGivern A; Wynter C V A; Whitehall V L J; Kambara T; Spring K J; Walsh M D; Barker M A; Arnold S; Simms L A; Leggett B A; Young J; Jass J R
Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer.
Familial cancer 2004;3(2):101-7.
2003: Mori Yuriko; Selaru Florin M; Sato Fumiaki; Yin Jing; Simms Lisa A; Xu Yan; Olaru Andreea; Deacu Elena; Wang Suna; Taylor Jennifer M; Young Joanne; Leggett Barbara; Jass Jeremy R; Abraham John M; Shibata David; Meltzer Stephen J
The impact of microsatellite instability on the molecular phenotype of colorectal tumors.
Cancer research 2003;63(15):4577-82.
2003: Jass J R; Barker M; Fraser L; Walsh M D; Whitehall V L J; Gabrielli B; Young J; Leggett B A
APC mutation and tumour budding in colorectal cancer.
Journal of clinical pathology 2003;56(1):69-73.
2002: Young Joanne; Barker Melissa; Fraser Leigh; Walsh Michael D; Spring Kevin; Biden Kelli G; Hopper John L; Leggett Barbara A; Jass Jeremy R
Mutation searching in colorectal cancer studies: experience with a denaturing high-pressure liquid chromatography system for exon-by-exon scanning of tumour suppressor genes.
Pathology 2002;34(6):529-33.
2002: Sato Fumiaki; Shibata David; Harpaz Noam; Xu Yan; Yin Jing; Mori Yuriko; Wang Suna; Olaru Andreea; Deacu Elena; Selaru Florin M; Kimos Martha C; Hytiroglou Prodromos; Young Joanne; Leggett Barbara; Gazdar Adi F; Toyooka Shinichi; Abraham John M; Meltzer Stephen J
Aberrant methylation of the HPP1 gene in ulcerative colitis-associated colorectal carcinoma.
Cancer research 2002;62(23):6820-2.
2002: Whitehall Vicki L J; Wynter Coral V A; Walsh Michael D; Simms Lisa A; Purdie David; Pandeya Nirmala; Young Joanne; Meltzer Stephen J; Leggett Barbara A; Jass Jeremy R
Morphological and molecular heterogeneity within nonmicrosatellite instability-high colorectal cancer.
Cancer research 2002;62(21):6011-4.
2002: Jass Jeremy R; Whitehall Vicki L J; Young Joanne; Leggett Barbara; Meltzer Stephen J; Matsubara Nagahide; Fishel Richard
Correspondence re: P. Laiho et al., Low-level microsatellite instability in most colorectal carcinomas. Cancer Res., 62: 1166-1170, 2002.
Cancer research 2002;62(20):5988-9; author reply 5989-90.
2002: Shibata David M; Sato Fumiaki; Mori Yuriko; Perry Kellie; Yin Jing; Wang Suna; Xu Yan; Olaru Andreea; Selaru Florin; Spring Kevin; Young Joanne; Abraham John M; Meltzer Stephen J
Hypermethylation of HPP1 is associated with hMLH1 hypermethylation in gastric adenocarcinomas.
Cancer research 2002;62(20):5637-40.
2002: Jass Jeremy R; Whitehall Vicki L J; Young Joanne; Leggett Barbara A
Emerging concepts in colorectal neoplasia.
Gastroenterology 2002;123(3):862-76.
2002: Wong Chung Fai; Liyou Nancy; Leggett Barbara; Young Joanne; Johnson Anthony; McManus Michael E
Association of the SULT1A1 R213H polymorphism with colorectal cancer.
Clinical and experimental pharmacology & physiology 2002;29(9):754-8.
2002: Mori Yuriko; Sato Fumiaki; Selaru Florin M; Olaru Andreea; Perry Kellie; Kimos Martha C; Tamura Gen; Matsubara Nagahide; Wang Suna; Xu Yan; Yin Jing; Zou Tong-Tong; Leggett Barbara; Young Joanne; Nukiwa Toshihiro; Stine O Colin; Abraham John M; Shibata David; Meltzer Stephen J
Instabilotyping reveals unique mutational spectra in microsatellite-unstable gastric cancers.
Cancer research 2002;62(13):3641-5.
2002: Jass J R; Walsh M D; Barker M; Simms L A; Young J; Leggett B A
Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability.
European journal of cancer (Oxford, England : 1990) 2002;38(7):858-66.
2002: Herath Nirmitha I; Kew Michael C; Walsh Michael D; Young Joanne; Powell Lawrie W; Leggett Barbara A; MacDonald Graeme A
Reciprocal relationship between methylation status and loss of heterozygosity at the p14(ARF) locus in Australian and South African hepatocellular carcinomas.
Journal of gastroenterology and hepatology 2002;17(3):301-7.
2002: Young J; Barker M; Robertson T; Nasioulas S; Tannenberg A; Buttenshaw R L; Knight N; Jass J R; Leggett B A
A case of myoepithelial carcinoma displaying biallelic inactivation of the tumour suppressor gene APC in a patient with familial adenomatous polyposis.
Journal of clinical pathology 2002;55(3):230-1.
2002: Jass Jereny R; Young Joanne; Leggett Barbara A
Evolution of colorectal cancer: change of pace and change of direction.
Journal of gastroenterology and hepatology 2002;17(1):17-26.
2001: Young J; Simms L A; Biden K G; Wynter C; Whitehall V; Karamatic R; George J; Goldblatt J; Walpole I; Robin S A; Borten M M; Stitz R; Searle J; McKeone D; Fraser L; Purdie D R; Podger K; Price R; Buttenshaw R; Walsh M D; Barker M; Leggett B A; Jass J R
Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis.
The American journal of pathology 2001;159(6):2107-16.
2001: Mori Y; Yin J; Rashid A; Leggett B A; Young J; Simms L; Kuehl P M; Langenberg P; Meltzer S J; Stine O C
Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability.
Cancer research 2001;61(16):6046-9.
2001: Whitehall V L; Walsh M D; Young J; Leggett B A; Jass J R
Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability.
Cancer research 2001;61(3):827-30.
2001: Leggett B A; Devereaux B; Biden K; Searle J; Young J; Jass J
Hyperplastic polyposis: association with colorectal cancer.
The American journal of surgical pathology 2001;25(2):177-84.
2001: Young J; Biden K G; Simms L A; Huggard P; Karamatic R; Eyre H J; Sutherland G R; Herath N; Barker M; Anderson G J; Fitzpatrick D R; Ramm G A; Jass J R; Leggett B A
HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(1):265-70.
2000: Jass J R; Young J; Leggett B A
Hyperplastic polyps and DNA microsatellite unstable cancers of the colorectum.
Histopathology 2000;37(4):295-301.
2000: Jass J R; Iino H; Ruszkiewicz A; Painter D; Solomon M J; Koorey D J; Cohn D; Furlong K L; Walsh M D; Palazzo J; Edmonston T B; Fishel R; Young J; Leggett B A
Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum.
Gut 2000;47(1):43-9.
2000: Iino H; Simms L; Young J; Arnold J; Winship I M; Webb S I; Furlong K L; Leggett B; Jass J R
DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer.
Gut 2000;47(1):37-42.
2000: Biemer-Hüttmann A E; Walsh M D; McGuckin M A; Simms L A; Young J; Leggett B A; Jass J R
Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):1909-16.
2000: Herath N I; Kew M C; Whitehall V L; Walsh M D; Jass J R; Khanna K K; Young J; Powell L W; Leggett B A; Macdonald G A
p73 is up-regulated in a subset of hepatocellular carcinomas.
Hepatology (Baltimore, Md.) 2000;31(3):601-5.
2000: Jass J R; Constable L; Sutherland R; Winterford C; Walsh M D; Young J; Leggett B A
Adenocarcinoma of colon differentiating as dome epithelium of gut-associated lymphoid tissue.
Histopathology 2000;36(2):116-20.
2000: Wilson P J; McGlinn E; Marsh A; Evans T; Arnold J; Wright K; Biden K; Young J; Wainwright B; Wicking C; Chenevix-Trench G
Sequence variants of DLC1 in colorectal and ovarian tumours.
Human mutation 2000;15(2):156-65.
1999: Macdonald G A; Tarish J; Whitehall V J; McCann S J; Mellick G D; Buttenshaw R L; Johnson A G; Young J; Leggett B A
No evidence of increased risk of colorectal cancer in individuals heterozygous for the Cys282Tyr haemochromatosis mutation.
Journal of gastroenterology and hepatology 1999;14(12):1188-91.
1999: Wynter C V; Simms L A; Buttenshaw R L; Biden K G; Young J; Leggett B A; Conrad R J; Schoch E M; Jass J R; Praga Pillay S
Angiogenic factor VEGF is decreased in human colorectal neoplasms showing DNA microsatellite instability.
The Journal of pathology 1999;189(3):319-25.
1999: Jass J R; Biden K G; Cummings M C; Simms L A; Walsh M; Schoch E; Meltzer S J; Wright C; Searle J; Young J; Leggett B A
Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways.
Journal of clinical pathology 1999;52(6):455-60.
1999: Biden K G; Simms L A; Cummings M; Buttenshaw R; Schoch E; Searle J; Gobe G; Jass J R; Meltzer S J; Leggett B A; Young J
Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability.
Oncogene 1999;18(5):1245-9.
1999: Iino H; Jass J R; Simms L A; Young J; Leggett B; Ajioka Y; Watanabe H
DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?
Journal of clinical pathology 1999;52(1):5-9.
1998: Simms L A; Radford-Smith G; Biden K G; Buttenshaw R; Cummings M; Jass J R; Young J; Meltzer S J; Leggett B A
Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers.
Oncogene 1998;17(15):2003-8.
1998: Wicking C; Simms L A; Evans T; Walsh M; Chawengsaksophak K; Beck F; Chenevix-Trench G; Young J; Jass J; Leggett B; Wainwright B
CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer.
Oncogene 1998;17(5):657-9.
1998: Jass J R; Do K A; Simms L A; Iino H; Wynter C; Pillay S P; Searle J; Radford-Smith G; Young J; Leggett B
Morphology of sporadic colorectal cancer with DNA replication errors.
Gut 1998;42(5):673-9.
1998: Young J; Simms L A; Tarish J; Buttenshaw R; Knight N; Anderson G J; Bell A; Leggett B
A family with attenuated familial adenomatous polyposis due to a mutation in the alternatively spliced region of APC exon 9.
Human mutation 1998;11(6):450-5.
1997: Wang S; Souza R F; Kong D; Yin J; Smolinski K N; Zou T T; Frank T; Young J; Flanders K C; Sugimura H; Abraham J M; Meltzer S J
Deficient transforming growth factor-beta1 activation and excessive insulin-like growth factor II (IGFII) expression in IGFII receptor-mutant tumors.
Cancer research 1997;57(13):2543-6.
1997: Souza R F; Yin J; Smolinski K N; Zou T T; Wang S; Shi Y Q; Rhyu M G; Cottrell J; Abraham J M; Biden K; Simms L; Leggett B; Bova G S; Frank T; Powell S M; Sugimura H; Young J; Harpaz N; Shimizu K; Matsubara N; Meltzer S J
Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors.
Cancer research 1997;57(12):2350-3.
1997: Simms L A; Zou T T; Young J; Shi Y Q; Lei J; Appel R; Rhyu M G; Sugimura H; Chenevix-Trench G; Souza R F; Meltzer S J; Leggett B A
Apparent protection from instability of repeat sequences in cancer-related genes in replication error positive gastrointestinal cancers.
Oncogene 1997;14(21):2613-8.
1997: Leggett B A; Cornwell M; Thomas L R; Buttenshaw R L; Searle J; Young J; Ward M
Characteristics of metachronous colorectal carcinoma occurring despite colonoscopic surveillance.
Diseases of the colon and rectum 1997;40(5):603-8.
1997: Biden K; Young J; Buttenshaw R; Searle J; Cooksley G; Xu D B; Leggett B
Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population.
Hepatology (Baltimore, Md.) 1997;25(3):593-7.
1997: Souza R F; Lei J; Yin J; Appel R; Zou T T; Zhou X; Wang S; Rhyu M G; Cymes K; Chan O; Park W S; Krasna M J; Greenwald B D; Cottrell J; Abraham J M; Simms L; Leggett B; Young J; Harpaz N; Meltzer S J
A transforming growth factor beta 1 receptor type II mutation in ulcerative colitis-associated neoplasms.
Gastroenterology 1997;112(1):40-5.
1997: Yin J; Kong D; Wang S; Zou T T; Souza R F; Smolinski K N; Lynch P M; Hamilton S R; Sugimura H; Powell S M; Young J; Abraham J M; Meltzer S J
Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas.
Human mutation 1997;10(6):474-8.
1996: Souza R F; Garrigue-Antar L; Lei J; Yin J; Appel R; Vellucci V F; Zou T T; Zhou X; Wang S; Rhyu M G; Cymes K; Chan O; Park W S; Krasna M J; Greenwald B D; Cottrell J; Abraham J M; Simms L; Leggett B; Young J; Harpaz N; Reiss M; Meltzer S J
Alterations of transforming growth factor-beta 1 receptor type II occur in ulcerative colitis-associated carcinomas, sporadic colorectal neoplasms, and esophageal carcinomas, but not in gastric neoplasms.
Human cell : official journal of Human Cell Research Society 1996;9(3):229-36.
1995: Leggett B; Young J; Buttenshaw R; Thomas L; Young B; Chenevix-Trench G; Searle J; Ward M
Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region.
British journal of cancer 1995;71(5):1070-3.
1995: Young J; Searle J; Buttenshaw R; Thomas L; Ward M; Chenevix-Trench G; Leggett B
An Alu VpA marker on chromosome I demonstrates that replication errors manifest at the adenoma-carcinoma transition in sporadic colorectal tumors.
Genes, chromosomes & cancer 1995;12(4):251-4.
1994: Young J; Buttenshaw R; Butterworth L; Ward M; Searle J; Leggett B; Chenevix-Trench G
Association of the SS genotype of the L-myc gene and loss of 18q sequences with a worse clinical prognosis in colorectal cancers.
Oncogene 1994;9(4):1053-6.
1993: Young J; Leggett B; Ward M; Thomas L; Buttenshaw R; Searle J; Chenevix-Trench G
Frequent loss of heterozygosity on chromosome 14 occurs in advanced colorectal carcinomas.
Oncogene 1993;8(3):671-5.
1993: Young J; Leggett B; Gustafson C; Ward M; Searle J; Thomas L; Buttenshaw R; Chenevix-Trench G
Genomic instability occurs in colorectal carcinomas but not in adenomas.
Human mutation 1993;2(5):351-4.
1990: Young J; Antalis T M; Chenevix-Trench G
BcII RFLP of the plasminogen activator inhibitor type 2 gene (PLANH) on chromosome 18q21-q23.
Nucleic acids research 1990;18(23):7196.

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