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James Young

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Eve-Irene Lepist; Kwan H Leung; Kyla M Smith; Sylvia Y M Yao; James D Young; Jing Zhang; Vijaya L Damaraju; Wendy P Gati; Edward Karpinski; Carol E Cass
Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1.
Hamidreza Vaziri; James D Young; David G Adams; Jocelyn M Baldwin; Stephen A Baldwin; Vincent Postis
Use of molecular modelling to probe the mechanism of the nucleoside transporter NupG.
Robert J Paproski; Sylvia Y M Yao; James D Young; Carol E Cass; David Evans; Nicole Favis; Roger J Zemp
Human concentrative nucleoside transporter 3 transfection with ultrasound and microbubbles in nucleoside transport deficient HEK293 cells greatly increases gemcitabine uptake.

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2013: Eve-Irene Lepist; Kwan H Leung; Kyla M Smith; Sylvia Y M Yao; James D Young; Jing Zhang; Vijaya L Damaraju; Wendy P Gati; Edward Karpinski; Carol E Cass
Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1.
Drug metabolism and disposition: the biological fate of chemicals 2013;41(4):916-22.
2013: Hamidreza Vaziri; James D Young; David G Adams; Jocelyn M Baldwin; Stephen A Baldwin; Vincent Postis
Use of molecular modelling to probe the mechanism of the nucleoside transporter NupG.
Molecular membrane biology 2013;30(2):114-28.
2013: Robert J Paproski; Sylvia Y M Yao; James D Young; Carol E Cass; David Evans; Nicole Favis; Roger J Zemp
Human concentrative nucleoside transporter 3 transfection with ultrasound and microbubbles in nucleoside transport deficient HEK293 cells greatly increases gemcitabine uptake.
PloS one 2013;8(2):e56423.
2012: Kate Witkowska; Sylvia Y M Yao; James D Young; Edward Karpinski; Amy M L Ng; Debbie O'Neill; Kyla M Smith; Christopher I Cheeseman
Human SLC2A9a and SLC2A9b isoforms mediate electrogenic transport of urate with different characteristics in the presence of hexoses.
American journal of physiology. Renal physiology 2012;303(4):F527-39.
2012: Gerard H M Huysmans; Michael J McPherson; Vincent Postis; Svetomir B Tzokov; Sylvia Y M Yao; James D Young; Jocelyn M Baldwin; Per A Bullough; Nathan Chan; Sarah E Deacon; Stephen A Baldwin
A urea channel from Bacillus cereus reveals a novel hexameric structure.
The Biochemical journal 2012;445(2):157-66.
2012: Vijaya L Damaraju; Delores Mowles; Amy Ng; Sylvia Yao; James D Young; Carol E Cass; Zeen Tong
Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine.
Nucleosides, nucleotides & nucleic acids 2012;31(3):236-55.
2011: Sara Kost; Benedict C Albensi; Carol E Cass; Kathryn Graham; Chao Sun; Wei Xiong; James D Young; Fiona E Parkinson
Behavioral effects of elevated expression of human equilibrative nucleoside transporter 1 in mice.
Behavioural brain research 2011;224(1):44-9.
2011: Kathryn Graham; Sylvia Yao; Lorelei Johnson; Delores Mowles; Amy Ng; Jodi Wilkinson; James D Young; Carol E Cass
Nucleoside transporter gene expression in wild-type and mENT1 knockout mice.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2011;89(2):236-45.
2011: Fiona E Parkinson; Vijaya L Damaraju; Kathryn Graham; Sylvia Y M Yao; Stephen A Baldwin; Carol E Cass; James D Young
Molecular biology of nucleoside transporters and their distributions and functions in the brain.
Current topics in medicinal chemistry 2011;11(8):948-72.
2011: Vijaya L Damaraju; Kyla M Smith; Delores Mowles; Ireneusz Nowak; Edward Karpinski; James D Young; Morris J Robins; Carol E Cass
Interaction of fused-pyrimidine nucleoside analogs with human concentrative nucleoside transporters: High-affinity inhibitors of human concentrative nucleoside transporter 1.
Biochemical pharmacology 2011;81(1):82-90.
2010: Robert J Paproski; Melinda Wuest; Hans-Sonke Jans; Kathryn Graham; Wendy P Gati; Steve McQuarrie; Alexander McEwan; John Mercer; James D Young; Carol E Cass
Biodistribution and uptake of 3'-deoxy-3'-fluorothymidine in ENT1-knockout mice and in an ENT1-knockdown tumor model.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(9):1447-55.
2010: Robert J Paproski; James D Young; Carol E Cass
Predicting gemcitabine transport and toxicity in human pancreatic cancer cell lines with the positron emission tomography tracer 3'-deoxy-3'-fluorothymidine.
Biochemical pharmacology 2010;79(4):587-95.
2009: Danielle E Johnson; Hui-wang Ai; Peter Wong; James D Young; Robert E Campbell; Joseph R Casey
Red fluorescent protein pH biosensor to detect concentrative nucleoside transport.
The Journal of biological chemistry 2009;284(31):20499-511.
2009: Melissa D Slugoski; Kyla M Smith; Amy M L Ng; Sylvia Y M Yao; Edward Karpinski; Carol E Cass; Stephen A Baldwin; James D Young
Conserved glutamate residues Glu-343 and Glu-519 provide mechanistic insights into cation/nucleoside cotransport by human concentrative nucleoside transporter hCNT3.
The Journal of biological chemistry 2009;284(25):17266-80.
2009: Melissa D Slugoski; Amy M L Ng; Sylvia Y M Yao; Colin C Lin; Ras Mulinta; Carol E Cass; Stephen A Baldwin; James D Young
Substituted cysteine accessibility method analysis of human concentrative nucleoside transporter hCNT3 reveals a novel discontinuous region of functional importance within the CNT family motif (G/A)XKX3NEFVA(Y/M/F).
The Journal of biological chemistry 2009;284(25):17281-92.
2009: Vijaya L Damaraju; Michael B Sawyer; John R Mackey; James D Young; Carol E Cass
Human nucleoside transporters: biomarkers for response to nucleoside drugs.
Nucleosides, nucleotides & nucleic acids 2009;28(5):450-63.
2009: Adam N Elwi; Vijaya L Damaraju; Michelle L Kuzma; Stephen A Baldwin; James D Young; Michael B Sawyer; Carol E Cass
Human concentrative nucleoside transporter 3 is a determinant of fludarabine transportability and cytotoxicity in human renal proximal tubule cell cultures.
Cancer chemotherapy and pharmacology 2009;63(2):289-301.
2008: Robert J Paproski; Amy M L Ng; Sylvia Y M Yao; Kathryn Graham; James D Young; Carol E Cass
The role of human nucleoside transporters in uptake of 3'-deoxy-3'-fluorothymidine.
Molecular pharmacology 2008;74(5):1372-80.
2008: Melissa D Slugoski; Kyla M Smith; Ras Mulinta; Amy M L Ng; Sylvia Y M Yao; Ellen L Morrison; Queenie O T Lee; Jing Zhang; Edward Karpinski; Carol E Cass; Stephen A Baldwin; James D Young
A conformationally mobile cysteine residue (Cys-561) modulates Na+ and H+ activation of human CNT3.
The Journal of biological chemistry 2008;283(36):24922-34.
2008: Robert J Paproski; Frank Visser; Jing Zhang; Tracey Tackaberry; Vijaya Damaraju; Stephen A Baldwin; James D Young; Carol E Cass
Mutation of Trp29 of human equilibrative nucleoside transporter 1 alters affinity for coronary vasodilator drugs and nucleoside selectivity.
The Biochemical journal 2008;414(2):291-300.
2008: James D Young; Sylvia Y M Yao; L Sun; Carol E Cass; Stephen A Baldwin
Human equilibrative nucleoside transporter (ENT) family of nucleoside and nucleobase transporter proteins.
Xenobiotica; the fate of foreign compounds in biological systems 2008;38(7-8):995-1021.
2008: Melissa D Slugoski; Amy M L Ng; Sylvia Y M Yao; Kyla M Smith; Colin C Lin; Jing Zhang; Edward Karpinski; Carol E Cass; Stephen A Baldwin; James D Young
A proton-mediated conformational shift identifies a mobile pore-lining cysteine residue (Cys-561) in human concentrative nucleoside transporter 3.
The Journal of biological chemistry 2008;283(13):8496-507.
2007: Sylvia Y M Yao; Amy M L Ng; Melissa D Slugoski; Kyla M Smith; Ras Mulinta; Edward Karpinski; Carol E Cass; Stephen A Baldwin; James D Young
Conserved glutamate residues are critically involved in Na+/nucleoside cotransport by human concentrative nucleoside transporter 1 (hCNT1).
The Journal of biological chemistry 2007;282(42):30607-17.
2007: Vijaya L Damaraju; Adam N Elwi; Charlene Hunter; Pat Carpenter; Cheryl Santos; Gerry M Barron; Xuejun Sun; Stephen A Baldwin; James D Young; John R Mackey; Michael B Sawyer; Carol E Cass
Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney.
American journal of physiology. Renal physiology 2007;293(1):F200-11.
2007: Frank Visser; Lijie Sun; Vijaya L Damaraju; Tracey Tackaberry; Yunshan Peng; Morris J Robins; Stephen A Baldwin; James D Young; Carol E Cass
Residues 334 and 338 in transmembrane segment 8 of human equilibrative nucleoside transporter 1 are important determinants of inhibitor sensitivity, protein folding, and catalytic turnover.
The Journal of biological chemistry 2007;282(19):14148-57.
2007: Jing Zhang; Frank Visser; Karen M King; Stephen A Baldwin; James D Young; Carol E Cass
The role of nucleoside transporters in cancer chemotherapy with nucleoside drugs.
Cancer metastasis reviews 2007;26(1):85-110.
2007: Melissa D Slugoski; Shaun K Loewen; Amy M L Ng; Kyla M Smith; Sylvia Y M Yao; Edward Karpinski; Carol E Cass; Stephen A Baldwin; James D Young
Specific mutations in transmembrane helix 8 of human concentrative Na+/nucleoside cotransporter hCNT1 affect permeant selectivity and cation coupling.
Biochemistry 2007;46(6):1684-93.
2007: Kyla M Smith; Melissa D Slugoski; Carol E Cass; Stephen A Baldwin; Edward Karpinski; James D Young
Cation coupling properties of human concentrative nucleoside transporters hCNT1, hCNT2 and hCNT3.
Molecular membrane biology 2007;24(1):53-64.
2007: Stephen A Baldwin; Glenn A McConkey; Carol E Cass; James D Young
Nucleoside transport as a potential target for chemotherapy in malaria.
Current pharmaceutical design 2007;13(6):569-80.
2006: Adam N Elwi; Vijaya L Damaraju; Stephen A Baldwin; James D Young; Michael B Sawyer; Carol E Cass
Renal nucleoside transporters: physiological and clinical implications.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2006;84(6):844-58.
2006: Jing Zhang; Kyla M Smith; Tracey Tackaberry; Xuejun Sun; Pat Carpenter; Melissa D Slugoski; Morris J Robins; Lars P C Nielsen; Ireneusz Nowak; Stephen A Baldwin; James D Young; Carol E Cass
Characterization of the transport mechanism and permeant binding profile of the uridine permease Fui1p of Saccharomyces cerevisiae.
The Journal of biological chemistry 2006;281(38):28210-21.
2006: Kay Barnes; Halina Dobrzynski; Sophie Foppolo; Paul R Beal; Fouzia Ismat; Elspeth R Scullion; Lijie Sun; James Tellez; Mabel W L Ritzel; William C Claycomb; Carol E Cass; James D Young; Rudi Billeter-Clark; Mark R Boyett; Stephen A Baldwin
Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH.
Circulation research 2006;99(5):510-9.
2006: Anne E King; Michael A Ackley; Carol E Cass; James D Young; Stephen A Baldwin
Nucleoside transporters: from scavengers to novel therapeutic targets.
Trends in pharmacological sciences 2006;27(8):416-25.
2006: Marilyn Lesley Clarke; Vijaya L Damaraju; Jing Zhang; Delores Mowles; Tracey Tackaberry; Thach Lang; Kyla M Smith; James D Young; Blake Tomkinson; Carol E Cass
The role of human nucleoside transporters in cellular uptake of 4'-thio-beta-D-arabinofuranosylcytosine and beta-D-arabinosylcytosine.
Molecular pharmacology 2006;70(1):303-10.
2006: Jing Zhang; Tracey Tackaberry; Mabel W L Ritzel; Taylor Raborn; Gerry M Barron; Stephen A Baldwin; James D Young; Carol E Cass
Cysteine-accessibility analysis of transmembrane domains 11-13 of human concentrative nucleoside transporter 3.
The Biochemical journal 2006;394(Pt 2):389-98.
2006: Jing Zhang; Xuejun Sun; Kyla M Smith; Frank Visser; Pat Carpenter; Gerry M Barron; Yunshan Peng; Morris J Robins; Stephen A Baldwin; James D Young; Carol E Cass
Studies of nucleoside transporters using novel autofluorescent nucleoside probes.
Biochemistry 2006;45(4):1087-98.
2006: Karen M King; Vijaya L Damaraju; Mark F Vickers; Sylvia Y M Yao; Thach Lang; Tracey Tackaberry; Delores Mowles; Amy M L Ng; James D Young; Carol E Cass
A comparison of the transportability, and its role in cytotoxicity, of clofarabine, cladribine, and fludarabine by recombinant human nucleoside transporters produced in three model expression systems.
Molecular pharmacology 2006;69(1):346-53.
2005: Jing Zhang; Kyla M Smith; Tracey Tackaberry; Frank Visser; Morris J Robins; Lars P C Nielsen; Ireneusz Nowak; Edward Karpinski; Stephen A Baldwin; James D Young; Carol E Cass
Uridine binding and transportability determinants of human concentrative nucleoside transporters.
Molecular pharmacology 2005;68(3):830-9.
2005: Kyla M Smith; Melissa D Slugoski; Shaun K Loewen; Amy M L Ng; Sylvia Y M Yao; Xing-Zhen Chen; Edward Karpinski; Carol E Cass; Stephen A Baldwin; James D Young
The broadly selective human Na+/nucleoside cotransporter (hCNT3) exhibits novel cation-coupled nucleoside transport characteristics.
The Journal of biological chemistry 2005;280(27):25436-49.
2005: Stephen A Baldwin; Sylvia Y M Yao; Ralph J Hyde; Amy M L Ng; Sophie Foppolo; Kay Barnes; Mabel W L Ritzel; Carol E Cass; James D Young
Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes.
The Journal of biological chemistry 2005;280(16):15880-7.
2005: Frank Visser; Jing Zhang; R Taylor Raborn; Stephen A Baldwin; James D Young; Carol E Cass
Residue 33 of human equilibrative nucleoside transporter 2 is a functionally important component of both the dipyridamole and nucleoside binding sites.
Molecular pharmacology 2005;67(4):1291-8.
2005: Laura Chow; Raymond Lai; Laith Dabbagh; Andrew R Belch; James D Young; Carol E Cass; John R Mackey
Analysis of human equilibrative nucleoside transporter 1 (hENT1) protein in non-Hodgkin's lymphoma by immunohistochemistry.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(4):558-64.
2005: Frank Visser; Stephen A Baldwin; R Elwyn Isaac; James D Young; Carol E Cass
Identification and mutational analysis of amino acid residues involved in dipyridamole interactions with human and Caenorhabditis elegans equilibrative nucleoside transporters.
The Journal of biological chemistry 2005;280(12):11025-34.
2005: Sambasivarao Damaraju; Jing Zhang; Frank Visser; Tracey Tackaberry; Jennifer Dufour; Kyla M Smith; Melissa D Slugoski; Mabel W L Ritzel; Stephen A Baldwin; James D Young; Carol E Cass
Identification and functional characterization of variants in human concentrative nucleoside transporter 3, hCNT3 (SLC28A3), arising from single nucleotide polymorphisms in coding regions of the hCNT3 gene.
Pharmacogenetics and genomics 2005;15(3):173-82.
2005: Simon G Patching; Stephen A Baldwin; Alexander D Baldwin; James D Young; Maurice P Gallagher; Peter J F Henderson; Richard B Herbert
The nucleoside transport proteins, NupC and NupG, from Escherichia coli: specific structural motifs necessary for the binding of ligands.
Organic & biomolecular chemistry 2005;3(3):462-70.
2005: John R Mackey; Carlos M Galmarini; Kathryn A Graham; Anil A Joy; Alain Delmer; Laith Dabbagh; Darryl Glubrecht; Laurence D Jewell; Raymond Lai; Thack Lang; John Hanson; James D Young; Hélène Merle-Béral; Jacques-Louis Binet; Carol E Cass; Charles Dumontet
Quantitative analysis of nucleoside transporter and metabolism gene expression in chronic lymphocytic leukemia (CLL): identification of fludarabine-sensitive and -insensitive populations.
Blood 2005;105(2):767-74.
2005: Vijaya L Damaraju; Frank Visser; Jing Zhang; Delores Mowles; Amy M L Ng; James D Young; Hiremagalur N Jayaram; Carol E Cass
Role of human nucleoside transporters in the cellular uptake of two inhibitors of IMP dehydrogenase, tiazofurin and benzamide riboside.
Molecular pharmacology 2005;67(1):273-9.
2004: Melissa D Slugoski; Shaun K Loewen; Amy M L Ng; Stephen A Baldwin; Carol E Cass; James D Young
Allelic isoforms of the H+/nucleoside co-transporter (CaCNT) from Candida albicans reveal separate high- and low-affinity transport systems for nucleosides.
Yeast (Chichester, England) 2004;21(15):1269-77.
2004: Jennifer Spratlin; Randeep Sangha; Darryl Glubrecht; Laith Dabbagh; James D Young; Charles Dumontet; Carol E Cass; Raymond Lai; John R Mackey
The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-treated pancreas adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(20):6956-61.
2004: Hao Xie; Simon G Patching; Maurice P Gallagher; Gary J Litherland; Adrian R Brough; Henrietta Venter; Sylvia Y M Yao; Amy M L Ng; James D Young; Richard B Herbert; Peter J F Henderson; Stephen A Baldwin
Purification and properties of the Escherichia coli nucleoside transporter NupG, a paradigm for a major facilitator transporter sub-family.
Molecular membrane biology 2004;21(5):323-36.
2004: Kyla M Smith; Amy M L Ng; Sylvia Y M Yao; Kathy A Labedz; Edward E Knaus; Leonard I Wiebe; Carol E Cass; Stephen A Baldwin; Xing-Zhen Chen; Edward Karpinski; James D Young
Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes.
The Journal of physiology 2004;558(Pt 3):807-23.
2004: Peter J Appleford; Mark Griffiths; Sylvia Y M Yao; Amy M L Ng; Eugene G Chomey; R Elwyn Isaac; David Coates; Ian A Hope; Carol E Cass; James D Young; Stephen A Baldwin
Functional redundancy of two nucleoside transporters of the ENT family (CeENT1, CeENT2) required for development of Caenorhabditis elegans.
Molecular membrane biology 2004;21(4):247-59.
2004: Qiang Li; Andrei Manolescu; Mabel W L Ritzel; Sylvia Yao; Melissa D Slugoski; James D Young; Xing-Zhen Chen; Chris I Cheeseman
Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(1):G236-42.
2004: Thack T Lang; James D Young; Carol E Cass
Interactions of nucleoside analogs, caffeine, and nicotine with human concentrative nucleoside transporters 1 and 2 stably produced in a transport-defective human cell line.
Molecular pharmacology 2004;65(4):925-33.
2004: Stephen A Baldwin; Paul R Beal; Sylvia Y M Yao; Anne E King; Carol E Cass; James D Young
The equilibrative nucleoside transporter family, SLC29.
Pflügers Archiv : European journal of physiology 2004;447(5):735-43.
2004: Mark F Vickers; Jing Zhang; Frank Visser; Tracey Tackaberry; Morris J Robins; Lars P C Nielsen; Ireneusz Nowak; Stephen A Baldwin; James D Young; Carol E Cass
Uridine recognition motifs of human equilibrative nucleoside transporters 1 and 2 produced in Saccharomyces cerevisiae.
Nucleosides, nucleotides & nucleic acids 2004;23(1-2):361-73.
2004: Shaun K Loewen; Sylvia Y M Yao; Melissa D Slugoski; Nadira N Mohabir; Raymond J Turner; John R Mackey; Joel Weiner; Maurice P Gallagher; Peter J F Henderson; Stephen A Baldwin; Carol E Cass; James D Young
Transport of physiological nucleosides and anti-viral and anti-neoplastic nucleoside drugs by recombinant Escherichia coli nucleoside-H(+) cotransporter (NupC) produced in Xenopus laevis oocytes.
Molecular membrane biology 2004;21(1):1-10.
2003: Jing Zhang; Frank Visser; Mark F Vickers; Thack Lang; Morris J Robins; Lars P C Nielsen; Ireneusz Nowak; Stephen A Baldwin; James D Young; Carol E Cass
Uridine binding motifs of human concentrative nucleoside transporters 1 and 3 produced in Saccharomyces cerevisiae.
Molecular pharmacology 2003;64(6):1512-20.
2003: Vijaya L Damaraju; Sambasivarao Damaraju; James D Young; Stephen A Baldwin; John Mackey; Michael B Sawyer; Carol E Cass
Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy.
Oncogene 2003;22(47):7524-36.
2003: Shaun K Loewen; Amy M L Ng; Nadira N Mohabir; Stephen A Baldwin; Carol E Cass; James D Young
Functional characterization of a H+/nucleoside co-transporter (CaCNT) from Candida albicans, a fungal member of the concentrative nucleoside transporter (CNT) family of membrane proteins.
Yeast (Chichester, England) 2003;20(8):661-75.
2003: Michael A Ackley; Ricardo J M Governo; Carol E Cass; James D Young; Stephen A Baldwin; Anne E King
Control of glutamatergic neurotransmission in the rat spinal dorsal horn by the nucleoside transporter ENT1.
The Journal of physiology 2003;548(Pt 2):507-17.
2003: Artur J Szkotak; Amy M L Ng; S F Paul Man; Stephen A Baldwin; Carol E Cass; James D Young; Marek Duszyk
Coupling of CFTR-mediated anion secretion to nucleoside transporters and adenosine homeostasis in Calu-3 cells.
The Journal of membrane biology 2003;192(3):169-79.
2002: Sylvia Y M Yao; Amy M L Ng; Mark F Vickers; Manickavasagam Sundaram; Carol E Cass; Stephen A Baldwin; James D Young
Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation.
The Journal of biological chemistry 2002;277(28):24938-48.
2002: Tony Reiman; Marilyn Lesley Clarke; Laith Dabbagh; Michaela Vsianska; Robert W Coupland; Andrew R Belch; Stephen A Baldwin; James D Young; Carol E Cass; John R Mackey
Differential expression of human equilibrative nucleoside transporter 1 (hENT1) protein in the Reed-Sternberg cells of Hodgkin's disease.
Leukemia & lymphoma 2002;43(7):1435-40.
2002: Sylvia Y M Yao; Amy M L Ng; Shaun K Loewen; Carol E Cass; Stephen A Baldwin; James D Young
An ancient prevertebrate Na+-nucleoside cotransporter (hfCNT) from the Pacific hagfish (Eptatretus stouti).
American journal of physiology. Cell physiology 2002;283(1):C155-68.
2002: Hanny Musa; Halina Dobrzynski; Z Berry; Fatima Abidi; Carol E Cass; James D Young; Stephen A Baldwin; Mark R Boyett
Immunocytochemical demonstration of the equilibrative nucleoside transporter rENT1 in rat sinoatrial node.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2002;50(3):305-9.
2002: Frank Visser; Mark F Vickers; Amy M L Ng; Stephen A Baldwin; James D Young; Carol E Cass
Mutation of residue 33 of human equilibrative nucleoside transporters 1 and 2 alters sensitivity to inhibition of transport by dilazep and dipyridamole.
The Journal of biological chemistry 2002;277(1):395-401.
2002: Marilyn Lesley Clarke; John R Mackey; Stephen A Baldwin; James D Young; Carol E Cass
The role of membrane transporters in cellular resistance to anticancer nucleoside drugs.
Cancer treatment and research 2002;112():27-47.
2002: Mark F Vickers; Rakesh Kumar; Frank Visser; Jing Zhang; Jahangir Charania; R Taylor Raborn; Stephen A Baldwin; James D Young; Carol E Cass
Comparison of the interaction of uridine, cytidine, and other pyrimidine nucleoside analogues with recombinant human equilibrative nucleoside transporter 2 (hENT2) produced in Saccharomyces cerevisiae.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2002;80(5):639-44.
2002: Miguel A Cabrita; Stephen A Baldwin; James D Young; Carol E Cass
Molecular biology and regulation of nucleoside and nucleobase transporter proteins in eukaryotes and prokaryotes.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2002;80(5):623-38.
2002: James D Young; Joseph R Casey; Reinhart A F Reithmeier
Meeting report: membrane proteins in health and disease.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2002;80(5):v-xi.
2002: John R Mackey; Lori L Jennings; Marilyn Lesley Clarke; Cheryl L Santos; Laith Dabbagh; Michaela Vsianska; Sheryl L Koski; Robert W Coupland; Stephen A Baldwin; James D Young; Carol E Cass
Immunohistochemical variation of human equilibrative nucleoside transporter 1 protein in primary breast cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(1):110-6.
2001: Artur J Szkotak; Amy M L Ng; Jolanta Sawicka; Stephen A Baldwin; S F Paul Man; Carol E Cass; James D Young; Marek Duszyk
Regulation of K(+) current in human airway epithelial cells by exogenous and autocrine adenosine.
American journal of physiology. Cell physiology 2001;281(6):C1991-2002.
2001: Manickavasagam Sundaram; Sylvia Y M Yao; Jean C Ingram; Z A Berry; Fatima Abidi; Carol E Cass; Stephen A Baldwin; James D Young
Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs.
The Journal of biological chemistry 2001;276(48):45270-5.
2001: Thack Lang; M Selner; James D Young; Carol E Cass
Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells.
Molecular pharmacology 2001;60(5):1143-52.
2001: Henriette Gourdeau; Marilyn Lesley Clarke; France Ouellet; Delores Mowles; M Selner; Annie Richard; N Lee; John R Mackey; James D Young; Jacques Jolivet; R G Lafrenière; Carol E Cass
Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines.
Cancer research 2001;61(19):7217-24.
2001: S R Hamilton; Sylvia Y M Yao; Jean C Ingram; D A Hadden; Mabel W L Ritzel; Maurice P Gallagher; Peter J F Henderson; Carol E Cass; James D Young; Stephen A Baldwin
Subcellular distribution and membrane topology of the mammalian concentrative Na+-nucleoside cotransporter rCNT1.
The Journal of biological chemistry 2001;276(30):27981-8.
2001: Manickavasagam Sundaram; Sylvia Y M Yao; Amy M L Ng; Carol E Cass; Stephen A Baldwin; James D Young
Equilibrative nucleoside transporters: mapping regions of interaction for the substrate analogue nitrobenzylthioinosine (NBMPR) using rat chimeric proteins.
Biochemistry 2001;40(27):8146-51.
2001: Sylvia Y M Yao; Amy M L Ng; Manickavasagam Sundaram; Carol E Cass; Stephen A Baldwin; James D Young
Transport of antiviral 3'-deoxy-nucleoside drugs by recombinant human and rat equilibrative, nitrobenzylthioinosine (NBMPR)-insensitive (ENT2) nucleoside transporter proteins produced in Xenopus oocytes.
Molecular membrane biology 2001;18(2):161-7.
2001: Lori L Jennings; C Hao; Miguel A Cabrita; Mark F Vickers; Stephen A Baldwin; James D Young; Carol E Cass
Distinct regional distribution of human equilibrative nucleoside transporter proteins 1 and 2 (hENT1 and hENT2) in the central nervous system.
Neuropharmacology 2001;40(5):722-31.
2001: Mabel W L Ritzel; Amy M L Ng; Sylvia Y M Yao; K Graham; Shaun K Loewen; Kyla M Smith; R Gary Ritzel; Delores Mowles; Pat Carpenter; Xing-Zhen Chen; Edward Karpinski; Ralph J Hyde; Stephen A Baldwin; Carol E Cass; James D Young
Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).
The Journal of biological chemistry 2001;276(4):2914-27.
2001: Sylvia Y M Yao; Manickavasagam Sundaram; Eugene G Chomey; Carol E Cass; Stephen A Baldwin; James D Young
Identification of Cys140 in helix 4 as an exofacial cysteine residue within the substrate-translocation channel of rat equilibrative nitrobenzylthioinosine (NBMPR)-insensitive nucleoside transporter rENT2.
The Biochemical journal 2001;353(Pt 2):387-93.
2001: Mark F Vickers; James D Young; Stephen A Baldwin; Michael J Ellison; Carol E Cass
Functional production of mammalian concentrative nucleoside transporters in Saccharomyces cerevisiae.
Molecular membrane biology 2001;18(1):73-9.
2001: Mabel W L Ritzel; Amy M L Ng; Sylvia Y M Yao; K Graham; Shaun K Loewen; Kyla M Smith; Ralph J Hyde; Edward Karpinski; Carol E Cass; Stephen A Baldwin; James D Young
Recent molecular advances in studies of the concentrative Na+-dependent nucleoside transporter (CNT) family: identification and characterization of novel human and mouse proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).
Molecular membrane biology 2001;18(1):65-72.
2001: Ralph J Hyde; Carol E Cass; James D Young; Stephen A Baldwin
The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoforms.
Molecular membrane biology 2001;18(1):53-63.
2000: Mark F Vickers; Sylvia Y M Yao; Stephen A Baldwin; James D Young; Carol E Cass
Nucleoside transporter proteins of Saccharomyces cerevisiae. Demonstration of a transporter (FUI1) with high uridine selectivity in plasma membranes and a transporter (FUN26) with broad nucleoside selectivity in intracellular membranes.
The Journal of biological chemistry 2000;275(34):25931-8.
2000: M D Parker; Ralph J Hyde; Sylvia Y M Yao; Louisa McRobert; Carol E Cass; James D Young; Glenn A McConkey; Stephen A Baldwin
Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy.
The Biochemical journal 2000;349(Pt 1):67-75.
2000: Kathryn A Graham; J Leithoff; IR Coe; Delores Mowles; John R Mackey; James D Young; Carol E Cass
Differential transport of cytosine-containing nucleosides by recombinant human concentrative nucleoside transporter protein hCNT1.
Nucleosides, nucleotides & nucleic acids 2000;19(1-2):415-34.
1999: John R Mackey; Sylvia Y M Yao; Kyla M Smith; Edward Karpinski; Stephen A Baldwin; Carol E Cass; James D Young
Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters.
Journal of the National Cancer Institute 1999;91(21):1876-81.
1999: Shaun K Loewen; Amy M L Ng; Sylvia Y M Yao; Carol E Cass; Stephen A Baldwin; James D Young
Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2.
The Journal of biological chemistry 1999;274(35):24475-84.
1999: Stephen A Baldwin; J R Mackey; Carol E Cass; James D Young
Nucleoside transporters: molecular biology and implications for therapeutic development.
Molecular medicine today 1999;5(5):216-24.
1999: Mark F Vickers; Rajam S Mani; Manickavasagam Sundaram; Douglas L Hogue; James D Young; Stephen A Baldwin; Carol E Cass
Functional production and reconstitution of the human equilibrative nucleoside transporter (hENT1) in Saccharomyces cerevisiae. Interaction of inhibitors of nucleoside transport with recombinant hENT1 and a glycosylation-defective derivative (hENT1/N48Q).
The Biochemical journal 1999;339 ( Pt 1)():21-32.
1999: Carol E Cass; James D Young; Stephen A Baldwin; Miguel A Cabrita; Kathryn A Graham; Mark Griffiths; Lori L Jennings; John R Mackey; Amy M L Ng; Mabel W L Ritzel; Mark F Vickers; Sylvia Y M Yao
Nucleoside transporters of mammalian cells.
Pharmaceutical biotechnology 1999;12():313-52.
1998: Rajam S Mani; J R Hammond; J M Marjan; Kathryn A Graham; James D Young; Stephen A Baldwin; Carol E Cass
Demonstration of equilibrative nucleoside transporters (hENT1 and hENT2) in nuclear envelopes of cultured human choriocarcinoma (BeWo) cells by functional reconstitution in proteoliposomes.
The Journal of biological chemistry 1998;273(46):30818-25.
1998: Mabel W L Ritzel; Sylvia Y M Yao; Amy M L Ng; John R Mackey; Carol E Cass; James D Young
Molecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine.
Molecular membrane biology 1998;15(4):203-11.
1998: John R Mackey; Rajam S Mani; M Selner; Delores Mowles; James D Young; JA Belt; CR Crawford; Carol E Cass
Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines.
Cancer research 1998;58(19):4349-57.
1998: Manickavasagam Sundaram; Sylvia Y M Yao; Amy M L Ng; Mark Griffiths; Carol E Cass; Stephen A Baldwin; James D Young
Chimeric constructs between human and rat equilibrative nucleoside transporters (hENT1 and rENT1) reveal hENT1 structural domains interacting with coronary vasoactive drugs.
The Journal of biological chemistry 1998;273(34):21519-25.
1998: Sylvia Y M Yao; WR Muzyka; John Elliott; Chris I Cheeseman; James D Young
Cloning and functional expression of a cDNA from rat jejunal epithelium encoding a protein (4F2hc) with system y+L amino acid transport activity.
The Biochemical journal 1998;330 ( Pt 2)():745-52.
1998: Sylvia Y M Yao; WR Muzyka; Carol E Cass; Chris I Cheeseman; James D Young
Evidence that the transport-related proteins BAT and 4F2hc are not specific for amino acids: induction of Na+-dependent uridine and pyruvate transport activity by recombinant BAT and 4F2hc expressed in Xenopus oocytes.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1998;76(5):859-65.
1998: CR Crawford; Carol E Cass; James D Young; JA Belt
Stable expression of a recombinant sodium-dependent, pyrimidine-selective nucleoside transporter (CNT1) in a transport-deficient mouse leukemia cell line.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1998;76(5):843-51.
1998: Carol E Cass; James D Young; Stephen A Baldwin
Recent advances in the molecular biology of nucleoside transporters of mammalian cells.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1998;76(5):761-70.
1997: Mark Griffiths; Sylvia Y M Yao; Fatima Abidi; Simon E V Phillips; Carol E Cass; James D Young; Stephen A Baldwin
Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta.
The Biochemical journal 1997;328 ( Pt 3)():739-43.
1997: Sylvia Y M Yao; Amy M L Ng; WR Muzyka; Mark Griffiths; Carol E Cass; Stephen A Baldwin; James D Young
Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues.
The Journal of biological chemistry 1997;272(45):28423-30.
1997: IR Coe; Mark Griffiths; James D Young; Stephen A Baldwin; Carol E Cass
Assignment of the human equilibrative nucleoside transporter (hENT1) to 6p21.1-p21.2.
Genomics 1997;45(2):459-60.
1997: H Boleti; IR Coe; Stephen A Baldwin; James D Young; Carol E Cass
Molecular identification of the equilibrative NBMPR-sensitive (es) nucleoside transporter and demonstration of an equilibrative NBMPR-insensitive (ei) transport activity in human erythroleukemia (K562) cells.
Neuropharmacology 1997;36(9):1167-79.
1997: A J Hirsh; Sylvia Y M Yao; James D Young; Chris I Cheeseman
Inhibition of glucose absorption in the rat jejunum: a novel action of alpha-D-glucosidase inhibitors.
Gastroenterology 1997;113(1):205-11.
1997: Mabel W L Ritzel; Sylvia Y M Yao; M Y Huang; John Elliott; Carol E Cass; James D Young
Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1).
The American journal of physiology 1997;272(2 Pt 1):C707-14.
1997: Mark Griffiths; Nick Beaumont; Sylvia Y M Yao; M Sundaram; C E Boumah; A Davies; F Y Kwong; I Coe; Carol E Cass; James D Young; Stephen A Baldwin
Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs.
Nature medicine 1997;3(1):89-93.
1996: Sylvia Y M Yao; Amy M L Ng; Mabel W L Ritzel; Wendy P Gati; C E Cass; James D Young
Transport of adenosine by recombinant purine- and pyrimidine-selective sodium/nucleoside cotransporters from rat jejunum expressed in Xenopus laevis oocytes.
Molecular pharmacology 1996;50(6):1529-35.
1996: Sylvia Y M Yao; C E Cass; James D Young
Transport of the antiviral nucleoside analogs 3'-azido-3'-deoxythymidine and 2',3'-dideoxycytidine by a recombinant nucleoside transporter (rCNT) expressed in Xenopus laevis oocytes.
Molecular pharmacology 1996;50(2):388-93.
1996: X Fang; Fiona E Parkinson; D A Mowles; James D Young; C E Cass
Functional characterization of a recombinant sodium-dependent nucleoside transporter with selectivity for pyrimidine nucleosides (cNT1rat) by transient expression in cultured mammalian cells.
The Biochemical journal 1996;317 ( Pt 2)():457-65.
1996: Douglas L Hogue; M J Ellison; James D Young; C E Cass
Identification of a novel membrane transporter associated with intracellular membranes by phenotypic complementation in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1996;271(16):9801-8.
1995: edith cline; Leonard I Wiebe; James D Young; J Samuel
Toxic effects of the novel protein UpI from the sea anemone Urticina piscivora.
Pharmacological research : the official journal of the Italian Pharmacological Society 1995;32(5):309-14.
1995: C S Cockram; S K Ho; S Q Zhu; James D Young
Insulin binding and internalization in hagfish red blood cells.
General and comparative endocrinology 1995;99(3):258-64.
1995: C S Cockram; W Kum; S K Ho; S O Zhu; James D Young
Binding and action of glucagon in cultured mouse astrocytes.
Glia 1995;13(2):141-6.
1995: Luis Felipe Barros; D L Yudilevich; S M Jarvis; N Beaumont; James D Young; Stephen A Baldwin
Immunolocalisation of nucleoside transporters in human placental trophoblast and endothelial cells: evidence for multiple transporter isoforms.
Pflügers Archiv : European journal of physiology 1995;429(3):394-9.
1994: Q Q Huang; Sylvia Y M Yao; Mabel W L Ritzel; Alan R P Paterson; C E Cass; James D Young
Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein.
The Journal of biological chemistry 1994;269(27):17757-60.
1994: C E Boumah; C M Harvey; Alan R P Paterson; Stephen A Baldwin; James D Young; C E Cass
Functional expression of the nitrobenzylthioinosine-sensitive nucleoside transporter of human choriocarcinoma (BeWo) cells in isolated oocytes of Xenopus laevis.
The Biochemical journal 1994;299 ( Pt 3)():769-73.
1994: Sylvia Y M Yao; W R Muzyka; John Elliott; Chris I Cheeseman; James D Young
Poly(A)+ RNA from the mucosa of rat jejunum induces novel Na(+)-dependent and Na(+)-independent leucine transport activities in in oocytes of Xenopus laevis.
Molecular membrane biology 1994;11(2):109-18.
1993: F Y Kwong; J S Wu; M M Shi; H E Fincham; A Davies; P J Henderson; Stephen A Baldwin; James D Young
Enzymic cleavage as a probe of the molecular structures of mammalian equilibrative nucleoside transporters.
The Journal of biological chemistry 1993;268(29):22127-34.
1993: Q Q Huang; C M Harvey; Alan R P Paterson; C E Cass; James D Young
Functional expression of Na(+)-dependent nucleoside transport systems of rat intestine in isolated oocytes of Xenopus laevis. Demonstration that rat jejunum expresses the purine-selective system N1 (cif) and a second, novel system N3 having broad specificity for purine and pyrimidine nucleosides.
The Journal of biological chemistry 1993;268(27):20613-9.
1993: Fiona E Parkinson; Alan R P Paterson; James D Young; C E Cass
Inhibitory effects of propentofylline on [3H]adenosine influx. A study of three nucleoside transport systems.
Biochemical pharmacology 1993;46(5):891-6.
1993: C M Harvey; W R Muzyka; Sylvia Y M Yao; Chris I Cheeseman; James D Young
Expression of rat intestinal L-lysine transport systems in isolated oocytes of Xenopus laevis.
The American journal of physiology 1993;265(1 Pt 1):G99-106.
1993: Sylvia Y M Yao; R George; James D Young
Reconstitution studies of amino acid transport system L in rat erythrocytes.
The Biochemical journal 1993;292 ( Pt 3)():655-60.
1992: F Y Kwong; H E Fincham; A Davies; N Beaumont; P J Henderson; James D Young; Stephen A Baldwin
Mammalian nitrobenzylthioinosine-sensitive nucleoside transport proteins. Immunological evidence that transporters differing in size and inhibitor specificity share sequence homology.
The Journal of biological chemistry 1992;267(30):21954-60.
1992: Luis Felipe Barros; N Beaumont; S M Jarvis; James D Young; P J Henderson; D L Yudilevich; C Thrasivoulou; Stephen A Baldwin
Nucleoside transporters in human placenta.
Biochemical Society transactions 1992;20(3):244S.
1992: C M Lee; W L Tung; James D Young
Tachykinin-stimulated inositol phospholipid hydrolysis and taurine release from human astrocytoma cells.
Journal of neurochemistry 1992;59(2):406-14.
1992: W Kum; S Q Zhu; S K Ho; James D Young; C S Cockram
Effect of insulin on glucose and glycogen metabolism and leucine incorporation into protein in cultured mouse astrocytes.
Glia 1992;6(4):264-8.
1991: James D Young; D A Fincham; C M Harvey
Cation and harmaline interactions with Na(+)-independent dibasic amino acid transport system y+ in human erythrocytes and in erythrocytes from a primitive vertebrate the pacific hagfish (Eptatretus stouti).
Biochimica et biophysica acta 1991;1070(1):111-8.
1991: D A Fincham; M W Wolowyk; James D Young
Nucleoside uptake by red blood cells from a primitive vertebrate, the Pacific hagfish (Eptatretus stouti), is mediated by a nitrobenzylthioinosine-insensitive transport system.
Biochimica et biophysica acta 1991;1069(1):123-6.
1991: V T F Yeung; C K Lai; C S Cockram; James D Young; M G Nicholls
Binding of brain and atrial natriuretic peptides to cultured mouse astrocytes and effect on cyclic GMP.
Journal of neurochemistry 1991;56(5):1684-9.
1991: F Y Kwong; H E Fincham; A Davies; P J Henderson; Stephen A Baldwin; James D Young
Antibodies and proteases as probes of the structures of mammalian nucleoside transporters.
Advances in experimental medicine and biology 1991;309A():427-30.
1990: Wendy P Gati; Andrew N Lin; T I Wang; James D Young; Alan R P Paterson
Parasite-induced processes for adenosine permeation in mouse erythrocytes infected with the malarial parasite Plasmodium yoelii.
The Biochemical journal 1990;272(1):277-80.
1990: S Q Zhu; W Kum; S K Ho; James D Young; C S Cockram
Structure-function relationships of insulin receptor interactions in cultured mouse astrocytes.
Brain research 1990;529(1-2):329-32.
1990: Chung-Ming Tse; James D Young
Glucose transport in fish erythrocytes: variable cytochalasin-B-sensitive hexose transport activity in the common eel (Anguilla japonica) and transport deficiency in the paddyfield eel (Monopterus albus) and rainbow trout (Salmo gairdneri).
The Journal of experimental biology 1990;148():367-83.
1989: Chung-Ming Tse; James D Young
Passive and carrier-mediated permeation of different nucleosides through the reconstituted nucleoside transporter.
Biochimica et biophysica acta 1989;985(3):343-6.
1989: James D Young
Structures and functions of mammalian nucleoside transporters.
Biochemical Society transactions 1989;17(3):444-7.
1989: C M Lee; W Kum; C S Cockram; R Teoh; James D Young
Functional substance P receptors on a human astrocytoma cell line (U-373 MG).
Brain research 1989;488(1-2):328-31.
1989: R Teoh; W Kum; C S Cockram; James D Young; M G Nicholls
Mouse astrocytes possess specific ANP receptors which are linked to cGMP production.
Clinical and experimental pharmacology & physiology 1989;16(4):323-7.
1989: M W Wolowyk; D A Fincham; James D Young
The effects of furosemide, piretanide and MK-196 on volume sensitive solute transport in fish erythrocytes.
Proceedings of the Western Pharmacology Society 1989;32():309-11.
1989: W Kum; C S Cockram; S Q Zhu; R Teoh; James D Young
Insulin binding to human astrocytoma cells and its effect on uridine incorporation into nucleic acid.
Journal of neurochemistry 1989;52(1):242-7.
1988: F Y Kwong; A Davies; Chung-Ming Tse; James D Young; P J Henderson; Stephen A Baldwin
Purification of the human erythrocyte nucleoside transporter by immunoaffinity chromatography.
The Biochemical journal 1988;255(1):243-9.
1988: D A Fincham; D K Mason; James D Young
Dibasic amino acid interactions with Na+-independent transport system asc in horse erythrocytes. Kinetic evidence of functional and structural homology with Na+-dependent system ASC.
Biochimica et biophysica acta 1988;937(1):184-94.
1988: James D Young; D K Mason; D A Fincham
Topographical similarities between harmaline inhibition sites on Na+-dependent amino acid transport system ASC in human erythrocytes and Na+-independent system asc in horse erythrocytes.
The Journal of biological chemistry 1988;263(1):140-3.
1987: F Y Kwong; Chung-Ming Tse; S M Jarvis; M Y Choy; James D Young
Purification and reconstitution studies of the nucleoside transporter from pig erythrocytes.
Biochimica et biophysica acta 1987;904(1):105-16.
1987: W Kum; C S Cockram; S Q Zhu; R Teoh; J Vallance-Owen; James D Young
Insulin binding and effects on pyrimidine nucleoside uptake and incorporation in cultured mouse astrocytes.
Journal of neurochemistry 1987;49(4):1293-300.
1987: D A Fincham; D K Mason; J Y Paterson; James D Young
Heterogeneity of amino acid transport in horse erythrocytes: a detailed kinetic analysis of inherited transport variation.
The Journal of physiology 1987;389():385-409.
1987: A H Good; J D Craik; S M Jarvis; F Y Kwong; James D Young; Alan R P Paterson; C E Cass
Characterization of monoclonal antibodies that recognize band 4.5 polypeptides associated with nucleoside transport in pig erythrocytes.
The Biochemical journal 1987;244(3):749-55.
1987: D A Fincham; M W Wolowyk; James D Young
Volume-sensitive taurine transport in fish erythrocytes.
The Journal of membrane biology 1987;96(1):45-56.
1986: F Y Kwong; Stephen A Baldwin; P R Scudder; S M Jarvis; M Y Choy; James D Young
Erythrocyte nucleoside and sugar transport. Endo-beta-galactosidase and endoglycosidase-F digestion of partially purified human and pig transporter proteins.
The Biochemical journal 1986;240(2):349-56.
1986: M W Wolowyk; D A Fincham; James D Young
A simple and convenient cell model for the characterization of volume sensitive taurine and GABA transport.
Proceedings of the Western Pharmacology Society 1986;29():51-3.
1985: D A Fincham; D K Mason; James D Young
Characterization of a novel Na+-independent amino acid transporter in horse erythrocytes.
The Biochemical journal 1985;227(1):13-20.
1983: J S Wu; F Y Kwong; S M Jarvis; James D Young
Identification of the erythrocyte nucleoside transporter as a band 4.5 polypeptide. Photoaffinity labeling studies using nitrobenzylthioinosine.
The Journal of biological chemistry 1983;258(22):13745-51.