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Lawrence Young

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Nicholas C D'Amato; Alyssa Dawson; Jeff Delrow; Krzysztof Mrózek; Takuya Osada; Julie Hanson Ostrander; Robin E Bachelder; Katie Bell; Alexander D Borowsky; Michelle L Bowie; Robert Cardiff; Timothy M Clay; Karl Simin; Christopher Sistrunk; Lisa D Yee; Lawrence J T Young; Victoria L Seewaldt
Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system.
Maria Lorna A de Leoz; Lawrence J T Young; Hyun Joo An; Scott R Kronewitter; Jaehan Kim; Suzanne Miyamoto; Alexander D Borowsky; Helen K Chew; Carlito B Lebrilla
High-mannose glycans are elevated during breast cancer progression.
Ellen Q Ingalla; Jamie K Miller; Jessica H Wald; Heather C Workman; Rouminder P Kaur; Lily Yen; William H D Fry; Alexander D Borowsky; Lawrence J T Young; Colleen Sweeney; Kermit L Carraway
Post-transcriptional mechanisms contribute to the suppression of the ErbB3 negative regulator protein Nrdp1 in mammary tumors.

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All Publications

2012: Nicholas C D'Amato; Alyssa Dawson; Jeff Delrow; Krzysztof Mrózek; Takuya Osada; Julie Hanson Ostrander; Robin E Bachelder; Katie Bell; Alexander D Borowsky; Michelle L Bowie; Robert Cardiff; Timothy M Clay; Karl Simin; Christopher Sistrunk; Lisa D Yee; Lawrence J T Young; Victoria L Seewaldt
Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system.
PloS one 2012;7(9):e45684.
2011: Maria Lorna A de Leoz; Lawrence J T Young; Hyun Joo An; Scott R Kronewitter; Jaehan Kim; Suzanne Miyamoto; Alexander D Borowsky; Helen K Chew; Carlito B Lebrilla
High-mannose glycans are elevated during breast cancer progression.
Molecular & cellular proteomics : MCP 2011;10(1):M110.002717.
2010: Ellen Q Ingalla; Jamie K Miller; Jessica H Wald; Heather C Workman; Rouminder P Kaur; Lily Yen; William H D Fry; Alexander D Borowsky; Lawrence J T Young; Colleen Sweeney; Kermit L Carraway
Post-transcriptional mechanisms contribute to the suppression of the ErbB3 negative regulator protein Nrdp1 in mammary tumors.
The Journal of biological chemistry 2010;285(37):28691-7.
2010: Azadeh Kheirolomoom; Dustin E Kruse; Shengping Qin; Katherine E Watson; Chun-Yen Lai; Lawrence J T Young; Robert Cardiff; Katherine W Ferrara
Enhanced in vivo bioluminescence imaging using liposomal luciferin delivery system.
Journal of controlled release : official journal of the Controlled Release Society 2010;141(2):128-36.
2010: Rebecca Baker; Claire V Kent; Rachel A Silbermann; John A Hassell; Lawrence J T Young; Louise R Howe
Pea3 transcription factors and wnt1-induced mouse mammary neoplasia.
PloS one 2010;5(1):e8854.
2008: Jamie K Miller; David L Shattuck; Ellen Q Ingalla; Lily Yen; Alexander D Borowsky; Lawrence J T Young; Robert Cardiff; Kermit L Carraway; Colleen Sweeney
Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer.
Cancer research 2008;68(20):8286-94.
2008: Lawrence J T Young
Mus tales: a hands-on view.
Journal of mammary gland biology and neoplasia 2008;13(3):343-9.
2008: Joshua Miller; Alexander D Borowsky; Teresa C Marple; Erik T McGoldrick; Lisa Dillard-Telm; Lawrence J T Young; Ralph Green
Folate, DNA methylation, and mouse models of breast tumorigenesis.
Nutrition reviews 2008;66 Suppl 1():S59-64.
2008: Lionel W Hebbard; Michèle Garlatti; Lawrence J T Young; Robert Cardiff; Robert Glen Oshima; Barbara Ranscht
T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model.
Cancer research 2008;68(5):1407-16.
2008: Patrizia Damonte; J Graeme Hodgson; Jane Qian Chen; Lawrence J T Young; Robert Cardiff; Alexander D Borowsky
Mammary carcinoma behavior is programmed in the precancer stem cell.
Breast cancer research : BCR 2008;10(3):R50.
2006: Lily Yen; Zhongwei Cao; Xiuli Wu; Ellen R Q Ingalla; Colin Baron; Lawrence J T Young; Jeffrey P Gregg; Robert Cardiff; Alexander D Borowsky; Colleen Sweeney; Kermit L Carraway
Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth.
Cancer research 2006;66(23):11279-86.
2006: Ruria Namba; Lawrence J T Young; Craig K Abbey; Lisa Kim; Patrizia Damonte; Alexander D Borowsky; Jinyi Qi; Clifford G Tepper; Carol L MacLeod; Robert Cardiff; Jeffrey P Gregg
Rapamycin inhibits growth of premalignant and malignant mammary lesions in a mouse model of ductal carcinoma in situ.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(8):2613-21.
2006: Ruria Namba; Jeannie E Maglione; Ryan R Davis; Colin A Baron; Stephenie Liu; Condie E Carmack; Lawrence J T Young; Alexander D Borowsky; Robert Cardiff; Jeffrey P Gregg
Heterogeneity of mammary lesions represent molecular differences.
BMC cancer 2006;6():275.
2005: Louise R Howe; Sung-Hee Chang; Kelly C Tolle; Rachelle Dillon; Lawrence J T Young; Robert Cardiff; Robert A Newman; Peiying Yang; Howard T Thaler; William J Muller; Clifford Hudis; Anthony M C Brown; Timothy Hla; Kotha Subbaramaiah; Andrew J Dannenberg
HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice.
Cancer research 2005;65(21):10113-9.
2005: Ruria Namba; Lawrence J T Young; Jeannie E Maglione; Erik T McGoldrick; Stephenie Liu; Gregory T Wurz; Michael W DeGregorio; Alexander D Borowsky; Carol L MacLeod; Robert Cardiff; Jeffrey P Gregg
Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ.
Breast cancer research : BCR 2005;7(6):R881-9.
2005: Alexander D Borowsky; Ruria Namba; Lawrence J T Young; Kent W Hunter; J Graeme Hodgson; Clifford G Tepper; Erik T McGoldrick; William J Muller; Robert Cardiff; Jeffrey P Gregg
Syngeneic mouse mammary carcinoma cell lines: two closely related cell lines with divergent metastatic behavior.
Clinical & experimental metastasis 2005;22(1):47-59.
2004: Derick H Lau; Linlang Guo; David R Gandara; Lawrence J T Young; Ling Xue
Is inhibition of cancer angiogenesis and growth by paclitaxel schedule dependent?
Anti-cancer drugs 2004;15(9):871-5.
2004: Ruria Namba; Jeannie E Maglione; Lawrence J T Young; Alexander D Borowsky; Robert Cardiff; Carol L MacLeod; Jeffrey P Gregg
Molecular characterization of the transition to malignancy in a genetically engineered mouse-based model of ductal carcinoma in situ.
Molecular cancer research : MCR 2004;2(8):453-63.
2004: Jeannie E Maglione; Erik T McGoldrick; Lawrence J T Young; Ruria Namba; Jeffrey P Gregg; Lin Liu; Drew Moghanaki; Lesley G Ellies; Alexander D Borowsky; Robert Cardiff; Carol L MacLeod
Polyomavirus middle T-induced mammary intraepithelial neoplasia outgrowths: single origin, divergent evolution, and multiple outcomes.
Molecular cancer therapeutics 2004;3(8):941-53.
2004: Katayoun Alavi Jessen; Stephenie Y Liu; Clifford G Tepper; Juliana Karrim; Erik T McGoldrick; Andrea Rosner; Robert Jay Munn; Lawrence J T Young; Alexander D Borowsky; Robert Cardiff; Jeffrey P Gregg
Molecular analysis of metastasis in a polyomavirus middle T mouse model: the role of osteopontin.
Breast cancer research : BCR 2004;6(3):R157-69.
2003: Albert K Man; Lawrence J T Young; John A Tynan; Jacqueline Lesperance; Mikala Egeblad; Zena Werb; Craig A Hauser; William J Muller; Robert Cardiff; Robert Glen Oshima
Ets2-dependent stromal regulation of mouse mammary tumors.
Molecular and cellular biology 2003;23(23):8614-25.
2002: Robert Cardiff; Howard A Bern; Leslie J Faulkin; Charles W Daniel; Gilbert H Smith; Lawrence J T Young; Daniel Medina; Murray B Gardner; Sefton R Wellings; Gopalan Shyamala; Raphael C Guzman; Lakshmanaswamy Rajkumar; Jason Yang; Gudmundur Thordarson; Satyabrata Nandi; Carol L MacLeod; Robert Glen Oshima; Albert K Man; Earl T Sawai; Jeffrey P Gregg; Anthony T W Cheung; Derick H Lau
Contributions of mouse biology to breast cancer research.
Comparative medicine 2002;52(1):12-31.
2001: Jeannie E Maglione; Drew Moghanaki; Lawrence J T Young; Cathyryne K Manner; Lesley G Ellies; S O Joseph; Benjamin Nicholson; Robert Cardiff; Carol L MacLeod
Transgenic Polyoma middle-T mice model premalignant mammary disease.
Cancer research 2001;61(22):8298-305.