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Rita Young

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Silvana A Vielma; Richard L Klein; Corinne A Levingston; M Rita I Young
Premalignant lesions skew spleen cell responses to immune modulation by adipocytes.
Anna-Maria A De Costa; Danielle N Justis; Corinne A Schuyler; M Rita I Young
Administration of a vaccine composed of dendritic cells pulsed with premalignant oral lesion lysate to mice bearing carcinogen-induced premalignant oral lesions stimulates a protective immune response.
David D Walker; Anna-Maria de Costa; Travis D Reeves; Corinne Schuyler; M Rita I Young
Immunological modulation by 1α,25-dihydroxyvitamin D3 in patients with squamous cell carcinoma of the head and neck.

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All Publications

2013: Silvana A Vielma; Richard L Klein; Corinne A Levingston; M Rita I Young
Premalignant lesions skew spleen cell responses to immune modulation by adipocytes.
Anticancer research 2013;33(5):1809-18.
2012: Anna-Maria A De Costa; Danielle N Justis; Corinne A Schuyler; M Rita I Young
Administration of a vaccine composed of dendritic cells pulsed with premalignant oral lesion lysate to mice bearing carcinogen-induced premalignant oral lesions stimulates a protective immune response.
International immunopharmacology 2012;13(3):322-30.
2012: David D Walker; Anna-Maria de Costa; Travis D Reeves; Corinne Schuyler; M Rita I Young
Immunological modulation by 1α,25-dihydroxyvitamin D3 in patients with squamous cell carcinoma of the head and neck.
Cytokine 2012;58(3):448-54.
2012: Anna-Maria A De Costa; Corinne A Schuyler; David D Walker; M Rita I Young
Characterization of the evolution of immune phenotype during the development and progression of squamous cell carcinoma of the head and neck.
Cancer immunology, immunotherapy : CII 2012;61(6):927-39.
2011: Jarrett E Walsh; M Rita I Young
TGF-beta regulation of focal adhesion proteins and motility of premalignant oral lesions via protein phosphatase 1.
Anticancer research 2011;31(10):3159-64.
2011: Anna-Maria De Costa; M Rita I Young
Immunotherapy for head and neck cancer: advances and deficiencies.
Anti-cancer drugs 2011;22(7):674-81.
2010: Jarrett E Walsh; M Rita I Young
Interrelationship between protein phosphatase 1 and TGF-{beta} in regulating motility and cytoskeletal architecture of endothelial cells.
Anticancer research 2010;30(12):4861-6.
2010: Adam W Mailloux; Anna-Maria A Clark; M Rita I Young
NK depletion results in increased CCL22 secretion and Treg levels in Lewis lung carcinoma via the accumulation of CCL22-secreting CD11b+CD11c+ cells.
International journal of cancer. Journal international du cancer 2010;127(11):2598-611.
2010: Jarrett E Walsh; Anna-Maria Clark; Terry A Day; M Boyd Gillespie; M Rita I Young
Use of alpha,25-dihydroxyvitamin D3 treatment to stimulate immune infiltration into head and neck squamous cell carcinoma.
Human immunology 2010;71(7):659-65.
2010: Jennifer K Mulligan; Steven A Rosenzweig; M Rita I Young
Tumor secretion of VEGF induces endothelial cells to suppress T cell functions through the production of PGE2.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(2):126-35.
2010: Jennifer Konopa Mulligan; M Rita I Young
Tumors induce the formation of suppressor endothelial cells in vivo.
Cancer immunology, immunotherapy : CII 2010;59(2):267-77.
2009: Joseph I Clark; Robert M Eisner; Craig Hofmeister; John Norton; Sachdev Thomas; Abdul Choudhury; Guy Petruzzelli; Deanne Lathers; M Rita I Young; Ann Lau; Bahman Emami
Phase I adjuvant radiation with docetaxel in high-risk head and neck cancer.
American journal of clinical oncology 2009;32(4):396-400.
2009: Jennifer K Mulligan; Terrence A. Day; M Boyd Gillespie; Steven A Rosenzweig; M Rita I Young
Secretion of vascular endothelial growth factor by oral squamous cell carcinoma cells skews endothelial cells to suppress T-cell functions.
Human immunology 2009;70(6):375-82.
2009: Adam W Mailloux; M Rita I Young
NK-dependent increases in CCL22 secretion selectively recruits regulatory T cells to the tumor microenvironment.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(5):2753-65.
2009: Jonathan S Kulbersh; Terrence A. Day; M Boyd Gillespie; M Rita I Young
1alpha,25-Dihydroxyvitamin D(3) to skew intratumoral levels of immune inhibitory CD34(+) progenitor cells into dendritic cells.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2009;140(2):235-40.
2008: Jennifer K Mulligan; Deanne M R Lathers; M Rita I Young
Tumors skew endothelial cells to disrupt NK cell, T-cell and macrophage functions.
Cancer immunology, immunotherapy : CII 2008;57(7):951-61.
2008: M Rita I Young
Use of carcinogen-induced premalignant oral lesions in a dendritic cell-based vaccine to stimulate immune reactivity against both premalignant oral lesions and oral cancer.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(2):148-56.
2007: M Rita I Young; Brad W Neville; Angela C Chi; Deanne M R Lathers; M Boyd Gillespie; Terrence A. Day
Oral premalignant lesions induce immune reactivity to both premalignant oral lesions and head and neck squamous cell carcinoma.
Cancer immunology, immunotherapy : CII 2007;56(7):1077-86.
2007: Jarrett E Walsh; Deanne M R Lathers; Angela C Chi; M Boyd Gillespie; Terrence A. Day; M Rita I Young
Mechanisms of tumor growth and metastasis in head and neck squamous cell carcinoma.
Current treatment options in oncology 2007;8(3):227-38.
2007: Eugene L Kanabrocki; May D Ryan; Deanne M R Lathers; N Achille; M Rita I Young; J V Cauteren; S Foley; M C Johnson; NC Friedman; G Siegel; Bernard A Nemchausky
Circadian distribution of serum cytokines in multiple sclerosis.
La Clinica terapeutica 2007;158(2):157-62.
2007: M Rita I Young; Brad W Neville; Angela C Chi; Deanne M R Lathers; M Boyd Gillespie; Terrence A. Day
Autocrine motility-stimulatory pathways of oral premalignant lesion cells.
Clinical & experimental metastasis 2007;24(2):131-9.
2007: Rashid M Rashid; John Lee; Jawed Fareed; M Rita I Young
In vitro heparan sulfate modulates the immune responses of normal and tumor-bearing mice.
Immunological investigations 2007;36(2):183-201.
2007: M Boyd Gillespie; Marcus W Moody; Fu-Shing Lee; Lynn J Poole; Joshua D. Hornig; Deanne M R Lathers; M Rita I Young; Terrence A. Day
Head and neck cancer recurrence and mortality in nonselective cyclooxygenase inhibitor users.
Archives of otolaryngology--head & neck surgery 2007;133(1):28-31.
2006: K Lawrence Yen; Marie-Josephe D Horner; Susan G Reed; Virginie G Daguise; Susan Bolick-Aldrich; M Rita I Young; Terrence A. Day; Patricia A Wood; James R Hebert
Head and neck cancer disparities in South Carolina: descriptive epidemiology, early detection, and special programs.
Journal of the South Carolina Medical Association (1975) 2006;102(7):192-200.
2006: Bradford A Woodworth; Deanne M R Lathers; Jeffrey G Neal; Margaret L Skinner; Mary S Richardson; M Rita I Young; Rodney J Schlosser
Immunolocalization of surfactant protein A and D in sinonasal mucosa.
American journal of rhinology 2006;20(4):461-5.
2006: M Rita I Young
Cytokine-containing gelfoam implants at a postsurgical tumor excision site to stimulate local immune reactivity.
International journal of cancer. Journal international du cancer 2006;119(1):133-8.
2006: M Rita I Young
Protective mechanisms of head and neck squamous cell carcinomas from immune assault.
Head & neck 2006;28(5):462-70.
2006: M Rita I Young; Melinda Cigal
Tumor skewing of CD34+ cell differentiation from a dendritic cell pathway into endothelial cells.
Cancer immunology, immunotherapy : CII 2006;55(5):558-68.
2006: Rashid M Rashid; John Lee; Jawed Fareed; M Rita I Young
In vivo heparan sulfate treatment alters the immune response of normal and LLC-bearing mice.
Immunopharmacology and immunotoxicology 2006;28(1):67-79.
2005: M Rita I Young; Deanne M R Lathers
Combination docetaxel plus vitamin D(3) as an immune therapy in animals bearing squamous cell carcinomas.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2005;133(4):611-8.
2005: Rashid M Rashid; Nicholas J Achille; John Lee; Deanne M R Lathers; M Rita I Young
Decreased T-cell proliferation and skewed immune responses in LLC-bearing mice.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2005;24(3):175-92.
2004: Anthony Sparano; Deanne M R Lathers; Nicholas J Achille; guy petruzzelli; M Rita I Young
Modulation of Th1 and Th2 cytokine profiles and their association with advanced head and neck squamous cell carcinoma.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2004;131(5):573-6.
2004: Deanne M R Lathers; Joseph I Clark; Nicholas J Achille; M Rita I Young
Phase 1B study to improve immune responses in head and neck cancer patients using escalating doses of 25-hydroxyvitamin D3.
Cancer immunology, immunotherapy : CII 2004;53(5):422-30.
2004: M Rita I Young
Trials and tribulations of immunotherapy as a treatment option for patients with squamous cell carcinoma of the head and neck.
Cancer immunology, immunotherapy : CII 2004;53(5):375-82.
2004: M Rita I Young
Tumor skewing of CD34+ progenitor cell differentiation into endothelial cells.
International journal of cancer. Journal international du cancer 2004;109(4):516-24.
2004: Deanne M R Lathers; M Rita I Young
Increased aberrance of cytokine expression in plasma of patients with more advanced squamous cell carcinoma of the head and neck.
Cytokine 2004;25(5):220-8.
2004: Alex A Romashko; M Rita I Young
Protein phosphatase-2A maintains focal adhesion complexes in keratinocytes and the loss of this regulation in squamous cell carcinomas.
Clinical & experimental metastasis 2004;21(4):371-9.
2004: M Rita I Young
Tumor-derived prostaglandin E2 and transforming growth factor-beta stimulate endothelial cell motility through inhibition of protein phosphatase-2A and involvement of PTEN and phosphatidylinositide 3-kinase.
Angiogenesis 2004;7(2):123-31.
2003: Deanne M R Lathers; Nicholas J Achille; M Rita I Young
Incomplete Th2 skewing of cytokines in plasma of patients with squamous cell carcinoma of the head and neck.
Human immunology 2003;64(12):1160-6.
2003: John John Brockenbrough; Sam J Marzo; Robert D Wurster; M Rita I Young
Bone wax prevents nystagmus after labyrinthine fenestration in guinea pigs.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2003;128(5):726-31.
2003: Jodi L Jackson; M Rita I Young
Protein phosphatase-2A regulates protein tyrosine phosphatase activity in Lewis lung carcinoma tumor variants.
Clinical & experimental metastasis 2003;20(4):357-64.
2003: James C Banich; Kristin Kolesiak; M Rita I Young
Chemoattraction of CD34+ progenitor cells and dendritic cells to the site of tumor excision as the first step of an immunotherapeutic approach to target residual tumor cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2003;26(1):31-40.
2003: Deanne M R Lathers; Nicholas J Achille; M Rita I Young
Dendritic cell development from mobilized peripheral blood CD34+ cells.
Methods in molecular biology (Clifton, N.J.) 2003;215():409-15.
2003: M Rita I Young; Shirley W Liu; Jeremy Meisinger
Protein phosphatase-2A restricts migration of Lewis lung carcinoma cells by modulating the phosphorylation of focal adhesion proteins.
International journal of cancer. Journal international du cancer 2003;103(1):38-44.
2002: M Rita I Young; Kristin Kolesiak; Jeremy Meisinger
Protein phosphatase-2A regulates endothelial cell motility and both the phosphorylation and the stability of focal adhesion complexes.
International journal of cancer. Journal international du cancer 2002;100(3):276-82.
2002: Bryan G Wachter; John P Leonetti; John Lee; Robert D Wurster; M Rita I Young
Silver nitrate injury in the rat sciatic nerve: a model of facial nerve injury.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2002;127(1):48-54.
2002: Nancy E Ziroli; Hanjo Na; James M Chow; James A Stankiewicz; Max Samter; M Rita I Young
Aspirin-sensitive versus non-aspirin-sensitive nasal polyp patients: analysis of leukotrienes/Fas and Fas-ligand expression.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2002;126(2):141-6.
2002: Lisa L Shafer; John A McNulty; M Rita I Young
Brain activation of monocyte-lineage cells: involvement of interleukin-6.
Neuroimmunomodulation 2002;10(5):295-304.
2002: Lisa L Shafer; John A McNulty; M Rita I Young
Brain activation of monocyte lineage cells: brain-derived soluble factors differentially regulate BV2 microglia and peripheral macrophage immune functions.
Neuroimmunomodulation 2002;10(5):283-94.
2002: Jodi L Jackson; M Rita I Young
Protein phosphatase-2A modulates the serine and tyrosine phosphorylation of paxillin in Lewis lung carcinoma tumor variants.
Clinical & experimental metastasis 2002;19(5):409-15.
2001: Deanne M R Lathers; J I Clark; Nicholas J Achille; M Rita I Young
Phase IB study of 25-hydroxyvitamin D(3) treatment to diminish suppressor cells in head and neck cancer patients.
Human immunology 2001;62(11):1282-93.
2001: Lisa L Shafer; John A McNulty; M Rita I Young
Assessment of melatonin's ability to regulate cytokine production by macrophage and microglia cell types.
Journal of neuroimmunology 2001;120(1-2):84-93.
2001: Deanne M R Lathers; Nicholas J Achille; Kristin Kolesiak; K Hulett; Anthony Sparano; guy petruzzelli; M Rita I Young
Increased levels of immune inhibitory CD34+ progenitor cells in the peripheral blood of patients with node positive head and neck squamous cell carcinomas and the ability of these CD34+ cells to differentiate into immune stimulatory dendritic cells.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2001;125(3):205-12.
2001: M Rita I Young; Kristin Kolesiak; Nicholas J Achille; Jeremy Meisinger; E Gonzalez; Shirley W Liu; T Wrone-Smith; Deanne M R Lathers
Impact of aging on immune modulation by tumor.
Cancer immunology, immunotherapy : CII 2001;50(6):315-20.
2001: S S Fowler; John P Leonetti; J C Banich; John Lee; Robert D Wurster; M Rita I Young
Duration of neuronal stretch correlates with functional loss.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2001;124(6):641-4.
2001: M Rita I Young; guy petruzzelli; Kristin Kolesiak; Nicholas J Achille; Deanne M R Lathers; Dmitry I Gabrilovich
Human squamous cell carcinomas of the head and neck chemoattract immune suppressive CD34(+) progenitor cells.
Human immunology 2001;62(4):332-41.
2000: Rajiv T Pandit; Deanne M R Lathers; N M Beal; T Garrity; M Rita I Young
CD34+ immune suppressive cells in the peripheral blood of patients with head and neck cancer.
The Annals of otology, rhinology, and laryngology 2000;109(8 Pt 1):749-54.
2000: C J Witt; S P Gabel; Jeremy Meisinger; G Werra; Shirley W Liu; M Rita I Young
Interrelationship between protein phosphatase-2A and cytoskeletal architecture during the endothelial cell response to soluble products produced by human head and neck cancer.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2000;122(5):721-7.
2000: JJ Donzelli; John P Leonetti; Robert D Wurster; John Lee; M Rita I Young
Neuroprotection due to irrigation during bipolar cautery.
Archives of otolaryngology--head & neck surgery 2000;126(2):149-53.
2000: M Rita I Young; Shirley W Liu; Jeremy Meisinger
Differences in association of the serine/threonine protein phosphatase PP-2A with microtubules of metastatic and nonmetastatic tumor cells.
Clinical & experimental metastasis 2000;18(5):407-13.
2000: KM Wiers; Deanne M R Lathers; MA Wright; M Rita I Young
Vitamin D3 treatment to diminish the levels of immune suppressive CD34+ cells increases the effectiveness of adoptive immunotherapy.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2000;23(1):115-24.
1999: Deanne M R Lathers; E Lubbers; N M Beal; MA Wright; M Rita I Young
Cultures derived from peripheral blood CD34+ progenitor cells of head and neck cancer patients and from cord blood are functionally different.
Human immunology 1999;60(12):1207-15.
1999: M Rita I Young; MA Wright; K Vellody; Deanne M R Lathers
Skewed differentiation of bone marrow CD34+ cells of tumor bearers from dendritic toward monocytic cells, and the redirection of differentiation toward dendritic cells by 1alpha,25-dihydroxyvitamin D3.
International journal of immunopharmacology 1999;21(10):675-88.
1999: S Gabel; J Benefield; Jeremy Meisinger; guy petruzzelli; M Rita I Young
Protein phosphatases 1 and 2A maintain endothelial cells in a resting state, limiting the motility that is needed for the morphogenic process of angiogenesis.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1999;121(4):463-8.
1999: M Rita I Young; MA Wright; Deanne M R Lathers; Kelly A N Messingham
Increased resistance to apoptosis by bone marrow CD34(+)progenitor cells from tumor-bearing mice.
International journal of cancer. Journal international du cancer 1999;82(4):609-15.
1999: Deanne M R Lathers; E Lubbers; MA Wright; M Rita I Young
Dendritic cell differentiation pathways of CD34+ cells from the peripheral blood of head and neck cancer patients.
Journal of leukocyte biology 1999;65(5):623-8.
1999: M Rita I Young; Deanne M R Lathers
Myeloid progenitor cells mediate immune suppression in patients with head and neck cancers.
International journal of immunopharmacology 1999;21(4):241-52.
1999: M Rita I Young; Kristin Kolesiak; M A Wright; Dmitry I Gabrilovich
Chemoattraction of femoral CD34+ progenitor cells by tumor-derived vascular endothelial cell growth factor.
Clinical & experimental metastasis 1999;17(10):881-8.
1998: JJ Donzelli; John P Leonetti; R Bergstrom; Robert D Wurster; M Rita I Young
Thermoprotective mechanisms of irrigation during bipolar cautery.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1998;119(3):153-8.
1998: MA Wright; KM Wiers; K Vellody; D Djordjevic; M Rita I Young
Stimulation of immune suppressive CD34+ cells from normal bone marrow by Lewis lung carcinoma tumors.
Cancer immunology, immunotherapy : CII 1998;46(5):253-60.
1998: KM Wiers; MA Wright; K Vellody; M Rita I Young
Failure of tumor-reactive lymph node cells to kill tumor in the presence of immune-suppressive CD34+ cells can be overcome with vitamin D3 treatment to diminish CD34+ cell levels.
Clinical & experimental metastasis 1998;16(3):275-82.
1997: T Garrity; Rajiv T Pandit; MA Wright; J Benefield; S Keni; M Rita I Young
Increased presence of CD34+ cells in the peripheral blood of head and neck cancer patients and their differentiation into dendritic cells.
International journal of cancer. Journal international du cancer 1997;73(5):663-9.
1997: guy petruzzelli; J Benefield; A D Taitz; S Fowler; J Kalkanis; S Scobercea; D West; M Rita I Young
Heparin-binding growth factor(s) derived from head and neck squamous cell carcinomas induce endothelial cell proliferations.
Head & neck 1997;19(7):576-82.
1997: M Rita I Young; MA Wright; Rajiv T Pandit
Myeloid differentiation treatment to diminish the presence of immune-suppressive CD34+ cells within human head and neck squamous cell carcinomas.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(2):990-6.
1997: KM Wiers; Y Lozano; Kelly A N Messingham; R J Metz; M Rita I Young
1alpha,25-dihydroxyvitamin D3 activates T cells of tumor bearers through protein phosphatase 2A.
Cancer immunology, immunotherapy : CII 1997;44(2):97-102.
1997: AM Vaidya; James M Chow; James A Stankiewicz; M Rita I Young; H L Mathews
Correlation of middle meatal and maxillary sinus cultures in acute maxillary sinusitis.
American journal of rhinology 1997;11(2):139-43.
1997: M Rita I Young; Y Lozano
Inhibition of tumor invasiveness by 1alpha,25-dihydroxyvitamin D3 coupled to a decline in protein kinase A activity and an increase in cytoskeletal organization.
Clinical & experimental metastasis 1997;15(2):102-10.
1997: M Rita I Young; MA Wright; Y Lozano; M M Prechel; J Benefield; J P Leonetti; S L Collins; guy petruzzelli
Increased recurrence and metastasis in patients whose primary head and neck squamous cell carcinomas secreted granulocyte-macrophage colony-stimulating factor and contained CD34+ natural suppressor cells.
International journal of cancer. Journal international du cancer 1997;74(1):69-74.
1997: J Benefield; Jeremy Meisinger; guy petruzzelli; M Rita I Young
Endothelial cell response to human head and neck squamous cell carcinomas involves downregulation of protein phosphatases-1/2A, cytoskeletal depolymerization and increased motility.
Invasion & metastasis 1997;17(4):210-20.
1997: J Jackson; Jeremy Meisinger; S Patel; Z C Lim; K Vellody; R Metz; M Rita I Young
Protein phosphatase-2A associates with the cytoskeleton to maintain cell spreading and reduced motility of nonmetastatic Lewis lung carcinoma cells: the loss of this regulatory control in metastatic cells.
Invasion & metastasis 1997;17(4):199-209.
1997: M Rita I Young; Y Lozano; A Djordjevic; G D Maier; M E Young
Tumor responsiveness to the metastasis-stimulatory effects of prostaglandin E2 is restricted by protein phosphatases.
Advances in experimental medicine and biology 1997;400A():323-8.
1997: Jeremy Meisinger; S Patel; K Vellody; R Bergstrom; J Benefield; Y Lozano; M Rita I Young
Protein phosphatase-2A association with microtubules and its role in restricting the invasiveness of human head and neck squamous cell carcinoma cells.
Cancer letters 1997;111(1-2):87-95.
1996: M Rita I Young; MA Wright; Y Lozano; J P Matthews; J Benefield; M M Prechel
Mechanisms of immune suppression in patients with head and neck cancer: influence on the immune infiltrate of the cancer.
International journal of cancer. Journal international du cancer 1996;67(3):333-8.
1996: M Rita I Young; Y Lozano; J Ihm; MA Wright; M M Prechel
Vitamin D3 treatment of tumor bearers can stimulate immune competence and reduce tumor growth when treatment coincides with a heightened presence of natural suppressor cells.
Cancer letters 1996;104(2):153-61.
1996: G D Maier; K Vellody; Jeremy Meisinger; A Djordjevic; Y Lozano; M Rita I Young
Protein kinase A regulates Lewis lung carcinoma adherence to extracellular matrix components and spontaneous metastasis.
Clinical & experimental metastasis 1996;14(3):314-22.
1996: M M Prechel; Y Lozano; MA Wright; J Ihm; M Rita I Young
Immune modulation by interleukin-12 in tumor-bearing mice receiving vitamin D3 treatments to block induction of immunosuppressive granulocyte/macrophage progenitor cells.
Cancer immunology, immunotherapy : CII 1996;42(4):213-20.
1996: M Rita I Young; MA Wright; J P Matthews; I Malik; M Prechel
Suppression of T cell proliferation by tumor-induced granulocyte-macrophage progenitor cells producing transforming growth factor-beta and nitric oxide.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(5):1916-22.
1996: J Benefield; guy petruzzelli; S Fowler; A Taitz; J Kalkanis; M Rita I Young
Regulation of the steps of angiogenesis by human head and neck squamous cell carcinomas.
Invasion & metastasis 1996;16(6):291-301.
1996: R J Metz; K Vellody; S Patel; R Bergstrom; Jeremy Meisinger; J Jackson; MA Wright; M Rita I Young
Vitamin D3 and ceramide reduce the invasion of tumor cells through extracellular matrix components by elevating protein phosphatase-2A.
Invasion & metastasis 1996;16(6):280-90.
1996: Y Lozano; A Taitz; guy petruzzelli; A Djordjevic; M Rita I Young
Prostaglandin E2-protein kinase A signaling and protein phosphatases-1 and -2A regulate human head and neck squamous cell carcinoma motility, adherence, and cytoskeletal organization.
Prostaglandins 1996;51(1):35-48.
1995: A Taitz; guy petruzzelli; Y Lozano; R Shankar; M Rita I Young
Bi-directional stimulation of adherence to extracellular matrix components by human head and neck squamous carcinoma cells and endothelial cells.
Cancer letters 1995;96(2):253-60.
1995: M Rita I Young; J Ihm; Y Lozano; MA Wright; M M Prechel
Treating tumor-bearing mice with vitamin D3 diminishes tumor-induced myelopoiesis and associated immunosuppression, and reduces tumor metastasis and recurrence.
Cancer immunology, immunotherapy : CII 1995;41(1):37-45.
1995: M M Prechel; Y Lozano; MA Wright; J Ihm; M Rita I Young
Ineffective immune enhancement by IL-12 in tumor-bearing mice whose immune depression is mediated by suppressive granulocyte-macrophage progenitor cells.
Cancer letters 1995;92(2):235-42.
1995: A Taitz; guy petruzzelli; A S Pak; MA Wright; J P Matthews; W F Raslan; Y Lozano; M Rita I Young
Immune parameters of mice bearing human head and neck cancer.
Cancer immunology, immunotherapy : CII 1995;40(5):283-91.
1995: M Rita I Young; M Montpetit; Y Lozano; A Djordjevic; S Devata; J P Matthews; S Yedavalli; G Chejfec
Regulation of Lewis lung carcinoma invasion and metastasis by protein kinase A.
International journal of cancer. Journal international du cancer 1995;61(1):104-9.
1995: G D Maier; MA Wright; Y Lozano; A Djordjevic; J P Matthews; M Rita I Young
Regulation of cytoskeletal organization in tumor cells by protein phosphatases-1 and -2A.
International journal of cancer. Journal international du cancer 1995;61(1):54-61.
1995: A S Pak; G Ip; MA Wright; M Rita I Young
Treating tumor-bearing mice with low-dose gamma-interferon plus tumor necrosis factor alpha to diminish immune suppressive granulocyte-macrophage progenitor cells increases responsiveness to interleukin 2 immunotherapy.
Cancer research 1995;55(4):885-90.
1995: A S Pak; M A Wright; J P Matthews; S L Collins; guy petruzzelli; M Rita I Young
Mechanisms of immune suppression in patients with head and neck cancer: presence of CD34(+) cells which suppress immune functions within cancers that secrete granulocyte-macrophage colony-stimulating factor.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(1):95-103.
1995: M Rita I Young; J P Matthews
Serotonin regulation of T-cell subpopulations and of macrophage accessory function.
Immunology 1995;84(1):148-52.
1994: M Rita I Young; S Charboneau; Y Lozano; A Djordjevic; M E Young
Activation of the protein kinase a signal transduction pathway by granulocyte-macrophage colony-stimulating factor or by genetic manipulation reduces cytoskeletal organization in Lewis lung carcinoma variants.
International journal of cancer. Journal international du cancer 1994;56(3):446-51.
1994: M Rita I Young; G McCloskey; MA Wright; A S Pak
Increasing infiltration and activation of CD8+ tumor-infiltrating lymphocytes after eliminating immune suppressive granulocyte/macrophage progenitor cells with low doses of interferon gamma plus tumor necrosis factor alpha.
Cancer immunology, immunotherapy : CII 1994;38(1):9-15.
1993: M Rita I Young; J Halpin; J Wang; MA Wright; J Matthews; A S Pak
1 alpha,25-dihydroxyvitamin D3 plus gamma-interferon blocks lung tumor production of granulocyte-macrophage colony-stimulating factor and induction of immunosuppressor cells.
Cancer research 1993;53(24):6006-10.
1993: M Rita I Young; J L Kut; M P Coogan; M A Wright; M E Young; J Matthews
Stimulation of splenic T-lymphocyte function by endogenous serotonin and by low-dose exogenous serotonin.
Immunology 1993;80(3):395-400.
1993: M Rita I Young; Y Lozano; A Djorjevic; G D Maier
Protein phosphatases limit tumor motility.
International journal of cancer. Journal international du cancer 1993;54(6):1036-41.
1993: M Rita I Young; Y Lozano; A Djordjevic; S Devata; J Matthews; M E Young; MA Wright
Granulocyte-macrophage colony-stimulating factor stimulates the metastatic properties of Lewis lung carcinoma cells through a protein kinase A signal-transduction pathway.
International journal of cancer. Journal international du cancer 1993;53(4):667-71.
1993: M Rita I Young; J Halpin; R Hussain; Y Lozano; A Djordjevic; S Devata; J P Matthews; MA Wright
Inhibition of tumor production of granulocyte-macrophage colony-stimulating factor by 1 alpha, 25-dihydroxyvitamin D3 reduces tumor motility and metastasis.
Invasion & metastasis 1993;13(4):169-77.
1992: M Rita I Young; MA Wright
Myelopoiesis-associated immune suppressor cells in mice bearing metastatic Lewis lung carcinoma tumors: gamma interferon plus tumor necrosis factor alpha synergistically reduces immune suppressor and tumor growth-promoting activities of bone marrow cells and diminishes tumor recurrence and metastasis.
Cancer research 1992;52(22):6335-40.
1992: M Rita I Young; Y Lozano; M Coogan; MA Wright; M E Young; J M Bagash
Stimulation of the metastatic properties of Lewis-lung-carcinoma cells by autologous granulocyte-macrophage colony-stimulating factor.
International journal of cancer. Journal international du cancer 1992;50(4):628-34.
1992: M Rita I Young; MA Wright; M Coogan; M E Young; J Bagash
Tumor-derived cytokines induce bone marrow suppressor cells that mediate immunosuppression through transforming growth factor beta.
Cancer immunology, immunotherapy : CII 1992;35(1):14-8.
1992: M Rita I Young; M E Young; Y Lozano; J M Bagash
Activation of protein kinase A increases the in vitro invasion, migration, and adherence to reconstituted basement membrane by Lewis lung carcinoma tumor cells.
Invasion & metastasis 1992;12(5-6):253-63.
1992: J L Kut; M Rita I Young; J W Crayton; M A Wright; M E Young
Regulation of murine T-lymphocyte function by spleen cell-derived and exogenous serotonin.
Immunopharmacology and immunotoxicology 1992;14(4):783-96.
1991: M Rita I Young; M E Young; Y Lozano; M Coogan; J M Bagash
Regulation of protein kinase A activation and prostaglandin E2-stimulated migration of Lewis lung carcinoma clones.
International journal of cancer. Journal international du cancer 1991;49(1):150-5.
1991: M Rita I Young; F Okada; M Tada; M Hosokawa; H Kobayashi
Association of increased tumor cell responsiveness to prostaglandin E2 with more aggressive tumor behavior.
Invasion & metastasis 1991;11(1):48-57.
1991: G P Duffie; M Rita I Young
Tumoricidal activity of alveolar and peritoneal macrophages of C57BL/6 mice bearing metastatic or nonmetastatic variants of Lewis lung carcinoma.
Journal of leukocyte biology 1991;49(1):8-14.
1991: M Rita I Young; MA Wright; M E Young
Antibodies to colony-stimulating factors block Lewis lung carcinoma cell stimulation of immune-suppressive bone marrow cells.
Cancer immunology, immunotherapy : CII 1991;33(3):146-52.
1990: M Rita I Young; M E Young; MA Wright
Myelopoiesis-associated suppressor-cell activity in mice with Lewis lung carcinoma tumors: interferon-gamma plus tumor necrosis factor-alpha synergistically reduce suppressor cell activity.
International journal of cancer. Journal international du cancer 1990;46(2):245-50.
1990: M Rita I Young; M E Young; MA Wright
Stimulation of immune-suppressive bone marrow cells by colony-stimulating factors.
Experimental hematology 1990;18(7):806-11.
1990: M Rita I Young; G P Duffie; Y Lozano; M E Young; MA Wright
Association of a functional prostaglandin E2-protein kinase A coupling with responsiveness of metastatic Lewis lung carcinoma variants to prostaglandin E2 and to prostaglandin E2-producing nonmetastatic Lewis lung carcinoma variants.
Cancer research 1990;50(10):2973-8.
1990: Nancy Ellis; G P Duffie; M Rita I Young; H T Wepsic
The effects of 16,16-dimethyl PGE2 and phosphodiesterase inhibitors on Con A blastogenic responses and NK cytotoxic activity of mouse spleen cells.
Journal of leukocyte biology 1990;47(4):371-7.
1989: M Rita I Young; M E Young
Effects of fish oil and corn oil diets on prostaglandin-dependent and myelopoiesis-associated immune suppressor mechanisms of mice bearing metastatic Lewis lung carcinoma tumors.
Cancer research 1989;49(8):1931-6.
1989: M Rita I Young; S Aquino; M E Young
Differential induction of hematopoiesis and immune suppressor cells in the bone marrow versus in the spleen by Lewis lung carcinoma variants.
Journal of leukocyte biology 1989;45(3):262-73.
1988: M Rita I Young; M E Young; K Kim
Regulation of tumor-induced myelopoiesis and the associated immune suppressor cells in mice bearing metastatic Lewis lung carcinoma by prostaglandin E2.
Cancer research 1988;48(23):6826-31.
1988: M Rita I Young; M E Young; H T Wepsic
The effect of recombinant murine interferon-gamma on the hematopoietic and immunological parameters of mice bearing metastatic Lewis lung carcinoma tumors.
Experimental hematology 1988;16(4):295-301.
1988: G P Duffie; R R Romanelli; Nancy Ellis; M Rita I Young; H T Wepsic
The effects of E series prostaglandins on blastogenic responses in vitro and graft vs. host responses in vivo.
Immunopharmacology and immunotoxicology 1988;10(4):597-615.
1987: M Rita I Young; R A Endicott; G P Duffie; H T Wepsic
Suppressor alveolar macrophages in mice bearing metastatic Lewis lung carcinoma tumors.
Journal of leukocyte biology 1987;42(6):682-8.
1987: D A Nikcevich; G P Duffie; M Rita I Young; Nancy Ellis; G E Kaufman; H T Wepsic
Stimulation of suppressor cells in the bone marrow and spleens of high dose cyclophosphamide-treated C57Bl/6 mice.
Cellular immunology 1987;109(2):349-59.
1987: M Rita I Young; M E Young; H T Wepsic
Effect of prostaglandin E2-producing nonmetastatic Lewis lung carcinoma cells on the migration of prostaglandin E2-responsive metastatic Lewis lung carcinoma cells.
Cancer research 1987;47(14):3679-83.
1987: M Rita I Young; Nancy Ellis; M E Young; H T Wepsic
Stimulation of hematopoiesis and bone marrow suppressor cells by the subcutaneous injection of linoleic acid.
Cellular immunology 1987;107(1):238-48.
1987: M Rita I Young; G P Duffie; M Newby
Adhesiveness and morphology of Lewis lung carcinoma variants influence their sensitivity to natural killer cytolysis and their metastatic capacity.
Invasion & metastasis 1987;7(2):96-108.
1987: M Rita I Young; M Newby; H T Wepsic
Hematopoiesis and suppressor bone marrow cells in mice bearing large metastatic Lewis lung carcinoma tumors.
Cancer research 1987;47(1):100-5.
1986: M Rita I Young; M Newby
Differential induction of suppressor macrophages by cloned Lewis lung carcinoma variants in mice.
Journal of the National Cancer Institute 1986;77(6):1255-60.
1986: Nancy Ellis; M Rita I Young; D A Nikcevich; M Newby; R Plioplys; H T Wepsic
Stimulation of prostaglandin-dependent macrophage suppressor cells by the subcutaneous injection of polyunsaturated fatty acids.
Cellular immunology 1986;102(2):251-60.
1986: M Rita I Young; C S Hoover
Inhibition of spleen cell cytotoxic capacity toward tumor by elevated prostaglandin E2 levels in mice bearing Lewis lung carcinoma.
Journal of the National Cancer Institute 1986;77(2):425-9.
1986: M Rita I Young; E Wheeler; M Newby
Macrophage-mediated suppression of natural killer cell activity in mice bearing Lewis lung carcinoma.
Journal of the National Cancer Institute 1986;76(4):745-50.
1986: D A Nikcevich; M Rita I Young; Nancy Ellis; M Newby; H T Wepsic
Stimulation of hematopoiesis in untreated and cyclophosphamide treated mice by the inhibition of prostaglandin synthesis.
Journal of immunopharmacology 1986;8(3):299-313.
1986: M Rita I Young; M Newby
Enhancement of Lewis lung carcinoma cell migration by prostaglandin E2 produced by macrophages.
Cancer research 1986;46(1):160-4.
1985: M Rita I Young; M Newby; J Meunier
Relationships between morphology, dissemination, migration, and prostaglandin E2 secretion by cloned variants of Lewis lung carcinoma.
Cancer research 1985;45(8):3918-23.
1984: M Rita I Young; S Knies
Prostaglandin E production by Lewis lung carcinoma: mechanism for tumor establishment in vivo.
Journal of the National Cancer Institute 1984;72(4):919-22.
1982: M Rita I Young; G Sundharadas; W D Cantarow; P R Kumar
Purification and functional characterization of a low molecular weight immune modulating factor produced by Lewis lung carcinoma.
International journal of cancer. Journal international du cancer 1982;30(4):517-24.